AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceHealth Care
Adoptive TransferImmunotherapy, AdoptiveImmunization, PassiveMice, Inbred C57BLGene Transfer TechniquesSpleenCD4-Positive T-LymphocytesT-LymphocytesMice, Inbred BALB CCD8-Positive T-LymphocytesEmbryo TransferGene Transfer, HorizontalMice, KnockoutLymphocyte ActivationMice, TransgenicT-Lymphocytes, RegulatoryLymphocyte TransfusionT-Lymphocyte SubsetsImmune ToleranceOvalbuminMice, SCIDDendritic CellsFlow CytometryInterferon-gammaLymph NodesTransfer (Psychology)T-Lymphocytes, CytotoxicImmunologic MemoryEncephalomyelitis, Autoimmune, ExperimentalCytokinesTh1 CellsDisease Models, AnimalAutoimmune DiseasesCells, CulturedFluorescence Resonance Energy TransferCytotoxicity, ImmunologicMelanoma, ExperimentalImmunity, CellularEpitopes, T-LymphocyteMice, Inbred NODB-LymphocytesGenetic VectorsReceptors, Antigen, T-CellRats, Inbred LewHypersensitivity, DelayedRNA, TransferTh2 CellsAntigensLymphocyte DepletionPatient TransferPhospholipid Transfer ProteinsInterleukin-2Mice, Inbred StrainsImmunity, Maternally-AcquiredMolecular Sequence DataImmunizationTransduction, GeneticMyelin-Oligodendrocyte GlycoproteinCell MovementTransfer FactorCell ProliferationKiller Cells, NaturalLymphocytes, Tumor-InfiltratingImmunosuppressionInterleukin-2 Receptor alpha SubunitInterleukin-10Forkhead Transcription FactorsSkin TransplantationImmunophenotypingClone CellsGenetic TherapyTime FactorsConjugation, GeneticImmunotherapyAntigens, CD8Dose-Response Relationship, ImmunologicAutoimmunityInterleukin-17Transplantation, HomologousCholesterol Ester Transfer ProteinsLymphopeniaAntigens, NeoplasmNuclear Transfer TechniquesAutoantigensElectron TransportCell DifferentiationRetinitisTh17 CellsIsoantigensCell SeparationT-Lymphocytes, Helper-InducerAntigens, CD11cRadiation ChimeraThymectomyMice, Inbred CBATendon TransferMice, Inbred DBAAdenoviridaeAmino Acid SequenceLung
ImmunotherapyLymphocytesAdoptively transferredFosterAntigen-specificTherapiesTregSyngeneicMurineCancerMelanomaCellularBiologicalTransplantationTumorCytotoxicityImmuneCytomegalovirusFamiliesVivoClinicalAdoptionParentsTherapeuticTumorsEmbryoCell receptorParentSearchChildrenTreatmentFindCells into a patientIncludeHumanNaturalSystemFamilyIndividualDesignsDataDays
Immunotherapy16
Lymphocytes9
  • Syngeneic lymphocytes were transferred from rodents heavily immunized against the tumor to inhibit growth of small established tumors, becoming the first example of ACT. (wikipedia.org)
  • In 2002, lymphodepletion using a nonmyeloablative chemotherapy regimen administered immediately before TIL transfer increased cancer regression, as well as the persistent oligoclonal repopulation of the host with the transferred lymphocytes. (wikipedia.org)
  • 3 Autologous lymphocytes genetically modified with the TCR for MART-1/Melan-A have been adoptively transferred to patients with advanced melanoma. (haematologica.org)
  • Although human CD20 has previously been described as functional selection marker and suicide gene after retroviral transfer to T lymphocytes, 9 , 10 the specificities of these T cells were unknown, and therefore a potential effect of CD20 on antigen-specific T-cell functions could not be investigated. (haematologica.org)
  • Moreover, lymphocytes collected from recipients transferred by lymphocytes from transgenic mice revealed less proliferative potential than lymphocytes obtained from control recipients. (diabetesjournals.org)
  • For tumors such as melanoma, in which tumor-specific T cells can be readily identified and isolated, the adoptive transfer of "tumor-infiltrating lymphocytes" (TILs) already appears to offer significant patient benefit and this approach now warrants further development. (eur.nl)
  • The transfer of lymphocytes or ethylene di-isocyanate (HDI), which are used in a serum from sensitized mice can cause clinical disease in naive variety of industries including polyurethane foam mice. (cdc.gov)
  • Transfer of immunity from immunized to non-immune host by administration of serum antibodies, or transplantation of lymphocytes (ADOPTIVE TRANSFER). (bvsalud.org)
  • Intravesical adoptive cell therapy (ACT) with tumor infiltrating lymphocytes (TIL) can potentially induce durable responses in bladder cancer while maximizing T cells at the tumor site. (bvsalud.org)
Adoptively transferred1
  • We also tested our hypothesis that intratumoral (i.t.) delivery of dendritic cells that had been transduced with IFN-alpha cDNA (DC-IFN-alpha) would enhance the tumor-homing and antitumor effectiveness of adoptively transferred Tc1 via induction of an IFN-gamma-inducible protein 10 (IP-10). (nih.gov)
Foster2
  • Upon acceptance of the receiving agency and the execution of the JFS 01334 "Recommendation for Transfer of a Foster or Adoptive Home" the sending agency is relieved of all responsibilities related to the approved adoptive family. (ohio.gov)
  • The National Training and Development Curriculum for Foster and Adoptive Parents (NTDC) was funded through a 5-year cooperative agreement with the U.S. Department of Health and Human Services, Administration for Children and Families, Children's Bureau. (hhs.gov)
Antigen-specific2
  • T-cell receptor (TCR) gene transfer is an attractive strategy for rapid in vitro generation of high numbers of antigen specific T cells. (haematologica.org)
  • Here we demonstrate how to activate antigen-specific TEM cells, induce adoptive DTH in Lewis rats and monitor the inflammatory response. (jove.com)
Therapies3
  • How are adoptive cellular therapies used in cancer treatment? (richardvigilantebooks.com)
  • These methods and results can help us to better understand immune reconstitution following hematopoietic cell transplantation, leading to future studies on the clinical application of adoptive T-cell therapies. (nature.com)
  • A better and deeper understanding of immune reconstitution following allo-HCT is required for further clinical application of these adoptive T-cell therapies. (nature.com)
Treg6
  • Adoptive transfer of induced-treg cells effectively attenuates murine airway allergic inflammation. (ca.gov)
  • In order to determine whether adoptive transfer of induced Treg cells generated in vitro can be used as an effective therapeutic approach to suppress airway allergic inflammation, exogenously induced Treg cells were infused into ovalbumin-sensitized mice prior to or during intranasal ovalbumin challenge. (ca.gov)
  • The results showed that adoptive transfer of induced Treg cells prior to allergen challenge markedly reduced airway hyperresponsiveness, eosinophil recruitment, mucus hyper-production, airway remodeling, and IgE levels. (ca.gov)
  • Moreover, adoptive transfer of induced Treg cells during allergen challenge also effectively attenuate airway inflammation and improve airway function, which are comparable to those by natural Treg cell infusion. (ca.gov)
  • Therefore, adoptive transfer of in vitro induced Treg cells may be a promising therapeutic approach to prevent and treat severe asthma. (ca.gov)
  • Treg deletion accelerates the development of atherosclerosis, and adoptive transfer Treg suppresses atherosclerosis [ 10 ]. (hindawi.com)
Syngeneic1
  • To establish a murine model in which a completely syngeneic lymphoma could be treated by adoptive transfer of syngeneic CAR-transduced T cells, we developed a CAR that could specifically recognize murine CD19. (ashpublications.org)
Murine1
  • To evaluate anti-CD19-CAR-transduced T cells in a murine model of adoptive T-cell therapy, we developed a CAR that specifically recognized murine CD19. (ashpublications.org)
Cancer5
  • The aim of adoptive T-cell therapy of cancer is to selectively confer immunity against tumor cells. (haematologica.org)
  • vivo activation and expansion of T cells or NK cells and passive transfer of these cells into the cancer patient. (richardvigilantebooks.com)
  • Adoptive T-cell therapy with T cells expressing chimeric antigen receptors (CARs) is an active area of cancer research. (ashpublications.org)
  • Their approach involves a twist on conventional adoptive T-cell therapy (ACT), in which the patient's own T cells are removed from the body and in some cases modified or engineered to recognise cancer cells. (ecancer.org)
  • Adoptive cellular therapy provides the promise of a potentially powerful general treatment for cancer. (eur.nl)
Melanoma1
  • Using C57BL/6 mice bearing intracranial (i.c.) ovalbumin-transfected melanoma (M05), we evaluated the efficacy and tumor homing of i.v. transferred type 1 or 2 CTLs (Tc1 or Tc2, respectively) prepared from ovalbumin-specific T-cell receptor-transgenic OT-1 mice. (nih.gov)
Cellular1
Biological7
  • Adoption permanently transfers parental rights and responsibilities from the biological parents to the adoptive parents. (fwjustice.org)
  • Once the adoption is finalized, the adoptive parents have the same legal rights and obligations as biological parents. (fwjustice.org)
  • We use data on stock market participation of Swedish adoptees and relate this to the investment behavior of both their biological and adoptive parents. (lu.se)
  • However, once we condition on having positive financial wealth, we find that nurture has a much stronger influence on risk-taking by children, and the evidence of a relationship between stock-holding of biological parents and their adoptive children becomes weaker. (lu.se)
  • To provide insight into this question, we take advantage of a unique feature of the Swedish adoption system whereby we observe both the biological and adoptive parents of adopted children. (lu.se)
  • We use administrative data on the portfolio choices of a large sample of adopted children born between 1950 and 1980 merged with similar information for their biological and adoptive parents--as well as corresponding data on own-birth children. (lu.se)
  • biological and adoptive parents. (lu.se)
Transplantation2
  • 4 In addition, TCRs for minor histocompatibility antigens, including HA-1 and HA-2, have been transferred to donor-derived virus-specific T cells to treat patients with hematologic malignancies after allogeneic stem cell transplantation. (haematologica.org)
  • and T-cell proliferation, adoptive transfer, and islet transplantation were performed to evaluate the PD-L1 transgene-mediated immune-protective mechanisms. (diabetesjournals.org)
Tumor3
  • These data suggest that Tc1-based adoptive transfer therapy may represent an effective modality for CNS tumors, particularly when combined with strategies that promote a type 1 polarized tumor microenvironment. (nih.gov)
  • Transfer of HSV-tk to DLI preserves the beneficial anti-tumor effect and allows in vivo elimination of donor T cells if severe GvHD occurs. (haematologica.org)
  • Adoptive transfer of lung APCs from nCB-exposed wild type to susceptible mice increased tumor incidence and caused early metastasis. (cdc.gov)
Cytotoxicity1
  • CD20-transduced T cells with and without co-transferred T-cell receptor were efficiently eliminated by complement dependent cytotoxicity induced by therapeutic anti-CD20 antibody rituximab. (haematologica.org)
Immune1
  • Vertical Transfer of Maternal Immune Cells - Maternal microchimeric cells promote fetal immune development and are linked to a lower number of respiratory infections in early life. (immunologypodcast.com)
Cytomegalovirus1
  • In this study, we investigated the use of CD20 as safety switch after retroviral transfer to T cells with different cytomegalovirus (CMV) specificities, and conclude that CD20 may be broadly applicable as safeguard in adoptive T-cell therapy. (haematologica.org)
Families4
  • In a courtroom at the Ramsey County Juvenile and Family Justice Center in St. Paul, a judge will finalize Ashley's adoption and that of nine other children to three other families from Ramsey County at an event meant to spotlight the urgent need for adoptive parents, particularly families of color. (tcdailyplanet.net)
  • Ashley is one of 348 so-called "waiting" children from around the state in need of adoptive families, children officials removed from unhealthy and dangerous living situations, terminating their parents' natural rights to parent them. (tcdailyplanet.net)
  • We would like to have a pool of prospective adoptive families that reflect the diversity of children in out-of-home placement. (tcdailyplanet.net)
  • Most dogs transferred are placed with adoptive families within a few days of becoming available for adoption at partner shelters. (shelbycountyreporter.com)
Vivo1
  • In vivo, i.v. transferred Tc1 trafficked efficiently into i.c. (nih.gov)
Clinical2
  • Co-transfer of a suicide gene would provide a desirable safety switch in clinical TCR gene therapy. (haematologica.org)
  • 12 , 13 Clinical trials in which patients with advanced B-cell malignancies receive T cells expressing anti-CD19 CARs are in early stages, and it is not known whether adoptive transfer of T cells targeting this self-antigen will be an effective therapy for B-cell malignancies. (ashpublications.org)
Adoption3
  • 1) "Sharing an adoptive homestudy" means forwarding an approved adoptive homestudy to a public children services agency (PCSA), private child placing agency (PCPA), or comparable agency in another state for consideration of potential adoption matches, or receiving an approved adoptive homestudy from a PCSA, PCPA, private non-custodial agency (PNA) or comparable agency in another state for the same purpose. (ohio.gov)
  • A copy of the adoption homestudy shall not be accepted directly from the approved adoptive parent or other individual. (ohio.gov)
  • Legal guardianship is a temporary arrangement that grants custodial rights, while adoption permanently transfers parental rights. (fwjustice.org)
Parents2
  • it was 'til-death-do-us-part," she said in telling an emotional story of how she and her husband, a physician, welcomed Ashley into their home in the belief God was backing them every step of the way to becoming adoptive parents. (tcdailyplanet.net)
  • The Saxes met Ashley in February at a special round-robin event designed to allow prospective adoptive parents and children to meet in a casual setting. (tcdailyplanet.net)
Therapeutic2
  • Administration of IL-2 after cell transfer enhanced therapeutic potential. (wikipedia.org)
  • Our study indicates that IL-27 or adoptive transfer of IL-27 loaded tDCs may be a new therapeutic approach in atherosclerosis. (hindawi.com)
Tumors1
  • Using single-cell sequencing, biophysical measurements of T cell receptor affinity, genetic engineering, and structural immunobiology, the Klebanoff lab aims to adapt adoptive T cell transfer for advanced solid tumors. (immunologypodcast.com)
Embryo2
Cell receptor1
  • T cell receptor (TCR) transfer experiments indicate that a major part of avidity is hardwired within the structure of the TCR. (mdc-berlin.de)
Parent6
  • An adoptive parent may provide other information to the receiving agency that the parent considers to be relevant. (ohio.gov)
  • 1) An agency shall not release or accept a homestudy for sharing or transferring purposes if it has been determined that the homestudy or a supporting document contains a false statement knowingly made by the adoptive parent. (ohio.gov)
  • a) Contact staff from the current recommending agency and the adoptive parent(s) to determine the reasons why the request to transfer is being made at this time. (ohio.gov)
  • b) Make at least one visit to the home and conduct a face-to-face meeting with each adoptive parent and all other household members. (ohio.gov)
  • c) Receive three new personal references for the adoptive parent(s) from persons who do not live with the family. (ohio.gov)
  • JAY, Okla. - An Oklahoma woman who was formerly named DHS Adoptive Parent of the Year received prison time in connection to a child abuse case. (kfor.com)
Search1
  • If the request is to transfer the homestudy, then the most recent report of the alleged perpetrator search of child abuse and neglect information from the statewide automated child welfare information system (SACWIS) shall also be forwarded to the receiving agency with the homestudy and related materials. (ohio.gov)
Children1
  • Spaulding for Children offers limited consultation to assist agencies with this transfer. (hhs.gov)
Treatment1
  • The challenges of adoptive cell transfer in the treatment of human renal cell carcinoma. (endourology.ph)
Find1
  • We recommend testing your press in multiple areas with a heat gun and practicing with extra transfers to find your "sweet spot. (bkdesignsandblanks.com)
Cells into a patient1
  • Adoptive cell transfer (ACT) is the transfer of cells into a patient. (wikipedia.org)
Include1
  • This would include adoptive, step and in-law versions of these. (findagrave.com)
Human1
  • ii) enhances the recognition and elimination of tumour cells by human gd T cells and (iii) drives expression of PD-L1 and its impact on adoptive cell transfer using novel CAR-T designs or gd T cells. (uni-freiburg.de)
Natural1
  • Some REs may even allow you to complete a natural cycle transfer with no birth control or medications. (nightlight.org)
System1
Family3
  • B) An agency shall not solicit homestudies or transfers from other agencies for the purpose of locating a family of a specific race, color or national origin. (ohio.gov)
  • D) If the approved adoptive family has signed a release of information the agency shall make the homestudy available to any other agency requesting a copy of the homestudy for sharing or transferring. (ohio.gov)
  • If you request an edit on a memorial that we created, who isn't in our family, we will sometimes transfer it to your safe keeping. (findagrave.com)
Individual1
  • Cells for adoptive therapy can be obtained either from the patient or from a separate individual. (richardvigilantebooks.com)
Designs1
  • BK Designs & Blanks, LLC is not responsible for operator or machine error when applying screen print, DTF, or sublimation transfers. (bkdesignsandblanks.com)
Data1
  • The data support the broad value of CD20 as safety switch in adoptive T-cell therapy. (haematologica.org)
Days1
  • F) If the agency in receipt of the homestudy determines that the homestudy or a supporting document contains a knowingly false statement, the agency in receipt of the homestudy shall not consider the homestudy in any matching conference or for consideration of a transfer and shall notify the sending agency in writing of the false statement within three days of the determination of the false statement. (ohio.gov)