Approximately 20-30% of patients chronically infected with hepatitis C virus (HCV) have persistently normal alanine transaminase (PNALT) levels. (medscape.com)
Controversies about the histological features of chronic HCV patients with persistently normal alanine transaminase levels: what can be done about the present definition? (pasteur.fr)
Improved Performance of Serum Alpha-Fetoprotein for Hepatocellular Carcinoma Diagnosis in HCV Cirrhosis with Normal Alanine Transaminase. (nih.gov)
Aminotransferase5
It is also called alanine aminotransferase (ALT or ALAT) and was formerly called serum glutamate-pyruvate transaminase or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues. (wikipedia.org)
In 2000, the American Association for Clinical Chemistry determined that the appropriate terminology for AST and ALT are aspartate aminotransferase and alanine aminotransferase. (wikipedia.org)
Serum triglyceride (TG), total-cholesterol (T-cho), glucose (Glu), alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), geranylgeranyltransferase (GGT) and albumin (Alb) levels were measured. (spandidos-publications.com)
First, look at liver enzymes: alanine transaminase (ALT) or aspartate aminotransferase (AST). (nih.gov)
Plasma alanine aminotransferase levels, hepatic expression of tumor necrosis factor-α, interleukin-6, fatty acid synthesis-related genes, oxidative stress biomarker 8-hydroxydeoxyguanosine (8-OHdG), and apoptosis marker terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL)-positive cells in the liver were decreased in the HW and PGZ groups. (researchgate.net)
Aspartate transaminase3
Serum ALT level, serum AST (aspartate transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. (wikipedia.org)
Hepatotoxicity: Monitor liver laboratory tests every 2 weeks during the first 3 months of treatment, then once a month and as clinically indicated, with more frequent testing in patients who develop transaminase and bilirubin elevations. (nih.gov)
Serum1
Is Serum Alanine Transaminase Level a Reliable Marker of Histological Disease in Chronic Hepatitis C Infection? (medscape.com)
Pyruvate2
ALT catalyzes the transfer of an amino group from L-alanine to α-ketoglutarate, the products of this reversible transamination reaction being pyruvate and L-glutamate. (wikipedia.org)
citation needed] L-alanine + α-ketoglutarate ⇌ pyruvate + L-glutamate ALT (and all aminotransferases) require the coenzyme pyridoxal phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid. (wikipedia.org)
Enzyme2
Alanine transaminase (ALT) is a transaminase enzyme (EC 2.6.1.2). (wikipedia.org)
The alanine transaminase (ALT) blood test measures the level of the enzyme ALT in the blood. (medlineplus.gov)
Liver disease1
The term transaminase is outdated and no longer used in liver disease. (wikipedia.org)
Level3
Alanine Transaminase Level: Reliable Marker of HCV Histological Disease? (medscape.com)
An elevated alanine transaminase (ALT) level is indicative of hepatocellular necrosis and has been used as a surrogate marker of liver injury. (medscape.com)
Liver function tests showed a depressed level of alanine transaminase and an abnormal HDL: LDL. (open.ac.uk)
Protein1
Alanine transaminase (ALT) is used by your body to metabolize protein. (healthline.com)
Blood1
Their blood was used to measure alanine transaminase (ALT), asparagine transaminase (AST), cholesterol, creatinine and glycosylated haemoglobin (HbA 1 C). (aaem.pl)
Activity1
We conducted Western blotting, real-time polymerase chain reaction (PCR), 3-(4,5-dimethylthiazol-2-yl)-2,5-triphenyl tetrazolium bromide (MTT) assays, liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) analysis, alanine transaminase (ALT) activity, histopathological analysis, and rotarod test. (nih.gov)
Increase1
This study determined whether 12 weeks of treatment with acetaminophen at half the maximum recommended daily dose causes an increase in alanine transaminase (ALT) in healthy adults participating in a clinical trial of the effect of acetaminophen on asthma control and severity. (nih.gov)
Greater1
This research is being done to determine if men with rising PSA after initial therapy for localized prostate cancer who display the Alanine/Alanine SOD2 genotype of MnSOD and supplement their diet with MPX have greater decrease in PSA slope following treatment compared to men that do not supplement with MPX. (dana-farber.org)