It is characterized by multifocal congenital dilatations of the intrahepatic bile ducts, which may be diffuse or limited, presenting in a sack form that produces cystic structures, which communicate with the biliary tree. (e-cmh.org)
Regional dilatation of intrahepatic bile ducts without tumor-induced obstruction was characteristic in diagnostic imaging. (nih.gov)
Pathological examination found chronic bile duct injury with DNA damage, precancerous/preinvasive lesions such as biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct in various sites of the large bile ducts, and invasive cholangiocarcinoma such as mass-forming type and intraductal growth-type intrahepatic cholangiocarcinoma and mainly papillary-type extrahepatic cholangiocarcinoma. (nih.gov)
The authors evaluated 128 bile duct carcinomas, 88 of the distal common bile duct and 40 of more proximal origin (28 perihilar carcinomas, 12 intrahepatic carcinomas), immunohistochemically for abnormalities in the expression of the products of the DPC4 and p53 tumor-suppressor genes. (umn.edu)
The patients with HCV infection exhibited an increased risk of liver cancer (HR: 25.10, 95 % CI: 20.9-30.2), gallbladder and extrahepatic bile duct cancer (HR: 2.60, 95 % CI: 1.42-4.73), ovarian cancer (HR: 5.15, 95 % CI: 1.98-13.4), and non-Hodgkin's lymphoma (HR: 2.30, 95 % CI: 1.34-3.96). (tmu.edu.tw)
Cholangiocarcinoma6
Bile duct neoplasms generally develop through a multistep process, involving different precursor pathways, ranging from the initial lesion, detectable only microscopically, i.e. biliary intraepithelial neoplasia, to the distinctive grades of IPNB until the final stage represented by invasive cholangiocarcinoma. (nih.gov)
To our knowledge, this is the eighth reported case of a cholangiocarcinoma associated with multiple bile duct hamartomas. (nih.gov)
Cholangiocarcinoma (CCA) is an aggressive cancer of the bile ducts. (nih.gov)
2. Primary follicular lymphoma of the extrahepatic bile duct mimicking a hilar cholangiocarcinoma: case report and review of the literature. (nih.gov)
Cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts ( COMMON HEPATIC DUCT ). (nih.gov)
Tumors7
Intraductal papillary neoplasms of the bile duct (IPNBs) represent a rare variant of biliary tumors characterized by a papillary growth within the bile duct lumen. (nih.gov)
They are not true neoplasms ( tumors ), but they are invasive, spreading into nearby tissue. (ivis.org)
For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. (icd10data.com)
The ISGACA collaboration focuses on the management of tumors in the bile duct, its mouth and in the duodenum. (liu.se)
A number of retrospective multicenter studies have already been done and the prospective ADAPTA study will investigate the choice of chemotherapy for tumors in the bile duct mouth. (liu.se)
The broad range of procedures includes minimally invasive intra-abdominal gastrointestinal surgery, endocrine tumors, retroperitoneal and extremity soft tissue neoplasms, as well as the entire range of skin tumors. (doctorwebsitedesign.com)
In addition, our experts focus on the management of thyroid tumor, breast benign and malignant neoplasms, retroperitoneal and extremity sarcomas, as well as the entire range of common and complex skin tumors. (doctorwebsitedesign.com)
Pancreas2
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified ( C25.9 ). (icd10data.com)
A malignant endocrine neoplasm arising from islets of langerhans of the pancreas. (icd10data.com)
There was not any finding of duodenal obstruction or pancreatic head neoplasm. (ispub.com)
Computed tomography demonstrated no mass effect, a normal pancreatic duct and a dilated common bile duct. (sages.org)
A primary malignant neoplasm of the pancreatic islet cells. (icd10data.com)
These results demonstrate that abnormalities in DPC4 and p53 gene expression are frequent in distal common bile duct carcinomas, just as they are in pancreatic ductal adenocarcinoma, suggesting that these two tumor types might share a similar molecular pathogenesis. (umn.edu)
Obstruction1
An 88-year-old man with biliary obstruction was diagnosed as having distal bile duct cancer using imaging examinations and endoscopic biopsy . (bvsalud.org)
Cancer3
Intraductal papillary neoplasm of the bile duct, also known as intraductal papillary biliary neoplasm, is a rare type of liver cancer. (wikipedia.org)
Mixed neuroendocrine-non-neuroendocrine neoplasm with mucinous adenocarcinoma and amphicrine carcinoma components in the bile duct: an autopsy case. (bvsalud.org)
Intraductal3
Here we report a rare case of Caroli's disease limited to one liver segment, which was initially misdiagnosed as an intraductal papillary neoplasm of the bile duct. (e-cmh.org)
In this report, we present a case of Caroli's disease that was misdiagnosed as an intraductal papillary neoplasm of the bile duct (IPNB) and was treated with segmentectomy. (e-cmh.org)
Abdominal CT ( Fig. 1A, B ) performed at the other hospital and abdominal magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP) ( Fig. 1C, D ) performed at our hospital revealed a localized bile duct dilatation measuring 2.0×0.8 cm in liver segment 5 without a demonstrable intraductal mass lesion and underlying steatosis of the liver. (e-cmh.org)
Dilatation2
Assuming that the lesion of the localized bile duct dilatation in liver segment 5 was due to an IPNB, we decided to perform surgery after consultation with the general surgery department because the possibility of malignancy with IPNB could not be excluded. (e-cmh.org)
We considered this bile-ducts dilatation as the consequence of external compression from the cysts. (ispub.com)
Conclusions With accurate preoperative risk assessment and strict treatment of basic diseases for elderly patients, if the stones in the common bile duct were cleared in laparoscopic surgery, the primary suture in elderly patients is feasible, safe, and valid. (researchsquare.com)
The tumor was unrelated to Caroli disease, primary sclerosing cholangitis, ulcerative colitis, or nonbiliary cirrhosis, as demonstrated by further clinical and histopathologic investigations, but probably was associated with the presence of multiple bile duct hamartomas. (nih.gov)
This study was designed to retrospective analysis the primary suture of the common bile duct and the T-tube drainage after laparoscopic choledochotomy to study the merits and demerits between primary suture and T-tube drainage in elderly patients. (researchsquare.com)
After clearing the stones, primary suture of the common bile duct could protect the patients from long-term T-tube drainage 12 . (researchsquare.com)
The primary suture of the common bile duct had been reported in previous studies, which showed that it was feasible 13-15 . (researchsquare.com)
In this retrospect study, we analyzed the feasibility of laparoscopic primary suture of the common bile duct in elderly patients, in order to improve their postoperative living quality. (researchsquare.com)
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. (icd10data.com)
Tumor-suppr1
They also show that proximal and distal bile duct carcinomas have different patterns of inactivation of tumor-suppressor genes, indicating that they often arise through different molecular mechanisms likely reflecting their differing etiologies. (umn.edu)
Recurrence1
Postoperative recurrence from multicentric origins occurred in some patients, as DNA-injured bile ducts have high carcinogenic potential. (nih.gov)
SCTR expression is upregulated during extrahepatic cholestasis induced by bile duct ligation and closely associated with cholangiocyte proliferative responses. (tamu.edu)
Hepatocellular1
By 4-weeks of age much of the liver is replaced by areas of ductular formation, cholangial neoplasms, and hepatocellular neoplasms in AL-TAg x AL-myc mice. (nih.gov)
Mucinous1
We report the first case of bile duct mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) that had a mucinous carcinoma component. (bvsalud.org)
Ductal1
Although an obstructing lesion was not found on the images, we considered the duct obstructed with a mass or parasite proximal to the dilated ductal area because size of the dilated ductal site was very limited and could not find any evidence of other bile duct disease. (e-cmh.org)
Diagnosis2
Complex and advanced investigations, mainly relying on magnetic resonance imaging (MRI) and cholangioscopy, are required to reach a correct diagnosis and to define an adequate bile duct mapping, which supports proper treatment. (nih.gov)
Pathology revealed absence of small terminal bile ducts affecting up to 60% of sampled portal tracts and senescence of many of the remaining small bile ducts, in keeping with a diagnosis of acute vanishing bile duct syndrome. (nih.gov)