Fasciola hepatica is one of the largest flukes of the world, reaching a length of 30 mm and a width of 13 mm (Fasciola gigantica, though, is even bigger and can reach up to 75 mm). (wikipedia.org)
Fascioliasis is a zoonotic disease caused by the foodborne trematode F. hepatica or F. gigantica , which has a complex life cycle and mainly affects sheep and cattle ( 2 ). (cdc.gov)
It belongs to the family Fasciolidae, which includes another species of liver fluke, Fasciola gigantica. (paraedu.ir)
Humoral response of sheep to F. gigantica was compared with the well known humoral response to F. hepatica , in order to explain the difference of susceptibility of sheep to these two parasites. (parasite-journal.org)
In this work, a lesser susceptibility of sheep to F. gigantica than to F. hepatica infection was confirmed. (parasite-journal.org)
In FhESP and FgESP, F. hepatica infected sheep serum reacted only with the lower molecular mass antigens, while F. gigantica infected sheep serum reacted with the lower and the higher molecular mass antigens. (parasite-journal.org)
Further investigation must be done to study the mechanism of resistance between the sheep infected with F. hepatica or F. gigantica . (parasite-journal.org)
La réponse humorale du Mouton induite par F. gigantica a été comparée à celle induite par F. hepatica , bien connue, afin d'expliquer les différences de sensibilité du Mouton à ces deux parasites. (parasite-journal.org)
Dans cette étude, la moindre sensibilité du Mouton à F. gigantica par rapport à F. hepatica a été confirmée. (parasite-journal.org)
La quantité d'IgG des moutons infestés par F. gigantica augmente dès la 2 ème semaine après infestation (SPI2) et atteint un pic en SPI13. (parasite-journal.org)
Dans les deux PES, les sérums des moutons Infestés par F. hepatica réagissent uniquement avec les antigènes majeurs de bas poids moléculaires alors que ceux des moutons infestés par F. gigantica réagissent avec les antigènes majeurs de bas et de hauts poids moléculaires. (parasite-journal.org)
D'autres investigations seraient nécessaires pour étudier les mécanismes de résistance des moutons infestés par F. hepatica ou par F. gigantica . (parasite-journal.org)
Geneetiliselt väga sarnane Fasciola gigantica esineb aga peamiselt vaid Aafrikas ja Aasias , kuna see liik eelistab soojemat kliimat. (wikipedia.org)
Parasite9
F. hepatica, which is distributed worldwide, has been known as an important parasite of sheep and cattle for decades and causes significant economic losses in these livestock species, up to £23 million in the UK alone. (wikipedia.org)
Although several lymnaeid species susceptible to F. hepatica have been described, the parasite develops only in one or two major species on each continent. (wikipedia.org)
Fasciola hepatica is a parasite that causes on average 3.2 million in losses in the agricultural sector every year worldwide. (sciencedaily.com)
origin, Colombia) with allopatric isolates of Fasciola hepatica from France or Fascioloides magna from the Czech Republic were carried out during five successive snail generations to determine if this lymnaeid might sustain complete larval development of either parasite. (cambridge.org)
The trematode Fasciola hepatica , or sheep liver fluke or common liver fluke, is a parasite that infects humans, cows and sheep. (wormbase.org)
The zoonotic worm parasite Fasciola hepatica secretes an abundance of cathepsin L peptidases that are associated with virulence, invasiveness, feeding and migration. (biomedcentral.com)
The helminth parasite Fasciola hepatica secretes cathepsin L cysteine proteases to invade its host, migrate through tissues and digest haemoglobin, its main source of amino acids. (maynoothuniversity.ie)
The liver fluke fasciola hepatica is a significant parasite of both cattle and sheep. (farmersguardian.com)
Host-parasite relationships of Fasciola hepatica in the White Mouse. (unc.edu)
Experimentally infected1
Several other lymnaeid snails may be naturally or experimentally infected with F. hepatica, but their role in transmission of the fluke is low. (wikipedia.org)
Liver flukes3
Differences in the compatibility of infection between the liver flukes Fascioloides magna and Fasciola hepatica in a Colombian population of the snail Galba sp. (cambridge.org)
In this article, we will explore the morphology of Fasciola hepatica, how it differs from other liver flukes, and how it can be identified. (paraedu.ir)
How does Fasciola hepatica differ from other liver flukes? (paraedu.ir)
Trematode1
Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes. (wikipedia.org)
Fasciolosis4
Fasciola hepatica is the causative agent of fasciolosis, a worldwide neglected and re-emerging zoonotic disease [ 1 ]. (biomedcentral.com)
Despite the pivotal role of leukocytes during fasciolosis in vivo, very little is known on early interactions between PMN and F. hepatica [ 11 ], even though PMN are the first granulocytes to be recruited to infection sites [ 13 ]. (biomedcentral.com)
Snails of the family Lymnaeidae act as intermediate hosts in the biological cycle of Fasciola hepatica, which is a biological agent of fasciolosis, a parasitic disease of medical importance for humans and animals. (fiocruz.br)
63.6% of total livers found to be positive for bovine fasciolosis were infected with F.hepatica where as F.giantica , mixed infection and immature or unidentified form of fasciola species recovered was 24.3%, 7.14% and 5%, respectively. (ispub.com)
Cattle6
however, fascioliasis acquired in the Netherlands has been reported only sporadically ( 4 ), even though F. hepatica infection in sheep and cattle is prevalent there ( 5 ). (cdc.gov)
Fasciola hepatica is distributed worldwide, especially in regions where sheep or cattle are raised. (paraedu.ir)
Correlation between climate data and land altitude for Fasciola hepatica infection in cattle in Santa Catarina, Brazil. (bvsalud.org)
First phenotypic and genotypic description of Fasciola hepatica infecting highland cattle in the state of Mexico, Mexico. (wikipedia.org)
These results indicate that F. hepatica wa s the most common liver fluke species that leads to high liver condemnation rates in cattle slaughtered, resulting into financial loss in the study area. (ispub.com)
The definitive hosts for F. hepatica are most mammals, among which sheep and cattle are the most important once. (ispub.com)
Daubneyi1
Untersuchung möglicher Zwischenwirte von Calicophoron daubneyi und Fasciola hepatica mittels Multiplex-PCR. (uni-muenchen.de)
Species2
Chlonorchis sinensis , Opisthorcis species, and Fasciola hepatica . (acsh.org)
Miracidial host-finding in Fasciola hepatica and Trichobilharzia ocellata is stimulated by species-specific glycoconjugates released from the host snails. (mpg.de)
Metacercariae2
In humans, the time taken for F. hepatica to mature from metacercariae into an adult fluke is roughly 3 to 4 months. (wikipedia.org)
Following ingestion of the encysted infective stage of F. hepatica (metacercariae), the parasites emerge in the intestine as newly excysted juveniles (NEJs). (biomedcentral.com)
Fecal samples5
Subsequently, F. hepatica eggs were detected in fecal samples. (cdc.gov)
however, fecal samples remained positive for F. hepatica eggs. (cdc.gov)
In this study, we evaluate the MM3-COPRO method for detection of Fasciola coproantigens in human fecal samples, and the usefulness of a new preservative/diluent, CoproGuard, developed for preservation of Fasciola coproantigens. (qxmd.com)
The MM3-COPRO assay was evaluated with 213 samples from healthy patients, 30 Fasciola positive fecal samples (according to the Kato-Katz method), and 83 samples from patients with other parasitic infections. (qxmd.com)
The use of CoproGuard enhanced coproantigen extraction without affecting the detection limit of the assay, and the antigenicity of Fasciola coproantigens in fecal samples stored at 37 degrees C was retained throughout the entire observation period (120 days). (qxmd.com)
Abstract1
Abstract - The phenotype of the hepatic inflammatory infiltrate and hepatic lymph nodes (HLN) was analysed in lambs primarily and challenge infected with Fasciola hepatica . (vetres.org)
Fascioliasis1
Fascioliasis is a food -borne parasitic disease that affects a range of animals , including humans caused by Fasciola hepatica . (bvsalud.org)
Protein3
Fasciola hepatica were collected from fresh beef livers and particulate fractions of whole flukes, 'tails' or 'heads' (anterior ends) assayed for adenylate cyclase (AC) activity and cyclic AMP concentration using a protein binding assay. (erowid.org)
Protein coding genes were predicted from the masked assembly using a combination of Snap , Fgenesh , Augustus , and the MAKER annotation pipeline using evidence from assembled transcripts, ESTs (GenBank EST database), and protein sequences from F. hepatica and related organisms. (wormbase.org)
2010). FH8 - A small EF-hand protein from Fasciola hepatica . (up.pt)
Clonorchis1
Fasciola hepatica is similar to another liver fluke, Clonorchis sinensis, which is also known as the Chinese liver fluke or the oriental liver fluke. (paraedu.ir)
Snails4
Intermediate hosts of F. hepatica are air-breathing freshwater snails from the family Lymnaeidae. (wikipedia.org)
In snails exposed to F. hepatica , 7 of 400 snails harboured several rediae and only two snails contained a small number of free cercariae on day 50 post-exposure. (cambridge.org)
The present work aimed to update and map the spatial distribution of the intermediate host snails of F. hepatica in Brazil. (fiocruz.br)
In Guilan Province, from the total of 4,830 different snails studied, only seven (0.35%) of L. gedrosiana were found to be infected with larvae stages of Fasciola sp. (scialert.net)
Parasites3
In the UK, Fasciola is generally common in farmed livestock which graze upon wetland pastures where the parasites intermediate snail host thrives. (wormbase.org)
All Fasciola positive specimens were detected with the MM3-COPRO assay (100% sensitivity) and there was no cross-reactivity with other common parasites present in the clinical specimens analyzed (100% specificity). (qxmd.com)
Despite this, our understanding of RNAi dynamics in many flatworm parasites, such as the temperate liver fluke (Fasciola hepatica), remains rudimentary. (aber.ac.uk)
Zoonotic1
Fasciola hepatica causes liver fluke disease, a worldwide neglected and re-emerging zoonotic disease, leading to hepatitis in humans and livestock. (biomedcentral.com)
ELISA1
MM3-ELISA detection of Fasciola hepatica coproantigens in preserved human stool samples. (qxmd.com)
Eggs4
Feces remained positive for F. hepatica eggs after each treatment. (cdc.gov)
Still, his feces remained positive for F. hepatica eggs. (cdc.gov)
Fasciola hepatica eggs are broadly ellipsoidal, operculated (having a lid-like structure), and measure 130-۱۵۰ μm by 60-۹۰ µm. (paraedu.ir)
The eggs are indistinguishable from those of Fasciola hepatica . (msdmanuals.com)
Humans1
Fasciola hepatica is a parasitic flatworm that infects the livers of various mammals, including humans. (paraedu.ir)
Stages2
The life cycle of F. hepatica goes through the intermediate host and several environmental larval stages. (wikipedia.org)
Firstly, all life stages examined possess, and express, core candidate RNAi effectors encouraging the hypothesis that all life stages of F. hepatica are RNAi competent. (aber.ac.uk)
Beef1
Fasciola hepatica , beef liver fluke, ova w.m. (flinnsci.com)
Immune2
We investigated for the first time whether F. hepatica soluble antigens ( Fh Ag) can also trigger NETosis and innate immune reactions in exposed ovine PMN. (biomedcentral.com)
The initial infection control against F. hepatica is provided by host innate immune leukocytes such as polymorphonuclear neutrophils (PMN), monocytes, eosinophils, and macrophages. (biomedcentral.com)
Iran1
The susceptibility of L. gedrosiana to F. hepatica under laboratory conditions has been reported in Iran. (scialert.net)
Host3
Fasciola hepatica occurs in the liver of a definitive host and its lifecycle is indirect. (wikipedia.org)
The FhCL3 peptidase involved in host invasion by F. hepatica is produced as a zymogen in the NEJs gut. (biomedcentral.com)
The genus Lymnea in general and L. Truncatula in particular are the most common intermediate host for F. hepatica. (ispub.com)
Humoral response to F. hepatica infection is similar to that previously described by several authors. (parasite-journal.org)
Similar biochemical diversity has been seen in the CaBP proteins from Fasciola hepatica. (brighton.ac.uk)
Main1
This research on sheep, one of the main victims of Fasciola hepatica, could mean an important step toward improving the effectiveness of vaccines in the future. (sciencedaily.com)
Finally, in vivo histopathological analysis on F. hepatica -parasitized liver tissue sections of sheep showed multifocal infiltration of inflammatory cells within liver parenchyma, and further fluorescence microscopy analyses confirmed NETs formation in vivo. (biomedcentral.com)