• Serum cytokines were analyzed by bead-based immunologic assays. (cdc.gov)
  • A diagnosis of PANS or PANDAS may be supported by the Cunningham Panel, a commercially available set of immunologic assays currently in clinical use. (diva-portal.org)
  • The Virology, Immunology & Microbiology Core Laboratory is a group of established investigators and very experienced technologists who provide a high level of expertise in state of the art technologies for processing human specimens, running HIV virologic and immunologic assays, running microbiological assays for associated STDs, providing access to state-of-the-art equipment for laboratory use, and developing new experimental protocols. (unccfar.org)
  • CAP inhibition assays (solid phase goat and sheep, tolerant vs non-tolerant sera pools, CM as inhibitor) without significant differences although in the tolerant pool a greater inhibition is observed. (biomedcentral.com)
  • beta-Internexin also shares some degree of homology with alpha-internexin, an intermediate filament-associated protein isolated and purified from rat spinal cord, which accounts for the immunologic cross-reactivity displayed by these polypeptides. (rupress.org)
  • The clinical presentation of so-called "atypical" CAP often is subacute and frequently is indolent. (medscape.com)
  • Historical clues and physical examination findings may suggest a causative pathogen, but the clinical signs and symptoms of CAP are not sufficiently specific to reliably differentiate the exact etiologic agent. (medscape.com)
  • Pediatric antiphospholipid syndrome: clinical and immunologic features of 121 patients in an international registry. (medscape.com)
  • The clinical and serologic phenotype of SLE patients with elevated levels of CB-CAPs has not been well described. (bmj.com)
  • Herein, we assessed the demographics, clinical manifestations, medical therapy, and laboratory variables of SLE patients with and without elevated CB-CAPs. (bmj.com)
  • Fisher's exact test and Kruskal-Wallis test were used to analyze differences in clinical and laboratory variables between CB-CAPs positive and CB-CAPs negative patients. (bmj.com)
  • Conclusion Narrowing the heterogenous clinical and immunologic features of SLE into endotypical subgroups is a crucial step toward precision medicine and personalized care in SLE. (bmj.com)
  • Hematopoietic stem cell transplantation rescues the immunologic phenotype and 22:262-5. (ehd.org)
  • Heparin-induced thrombocytopenia Platelet destruction can develop because of immunologic causes (viral infection, drugs, connective tissue or lymphoproliferative disorders, blood transfusions) or nonimmunologic causes (sepsis. (msdmanuals.com)
  • Community-acquired pneumonia (CAP) is one of the most common infectious diseases and an important cause of mortality and morbidity worldwide. (medscape.com)
  • The authors evaluated blood cell parameters and markers of platelet activation in mice exposed to concentrated ambient particulate matter (CAPs) from the San Joaquin Valley of California, a region with severe particulate matter (PM) pollution episodes. (cdc.gov)
  • Background Cell-bound complement activation products (CB-CAPs), including erythrocyte-bound C4d (EC4d) and B-lymphocyte-bound C4d (BC4d), in a multi-analyte assay with algorithm (MAP) represent an important addition to the diagnostic armamentarium of SLE. (bmj.com)
  • Tutorial in undercooked pork or immunologic diseases. (pixelflyte.com)
  • With the capabilities of acting as antiatherosclerotic, immunologic, antimicrobial, and antiviral agents, as well as potent antioxidants, proanthocyanidins are being considered as potential therapeutics to alleviate various chronic diseases. (ucdavis.edu)
  • Bristol-Myers Squibb is a one of the leading global specialty biopharmaceutical companies focused on the development of treatments targeting serious diseases like cancer, inflammatory, immunologic, cardiovascular or fibrotic diseases. (macrotrends.net)
  • Data from an early-stage study showed that Icosavax's (ICVX) investigational RSV vaccine exhibited sustained immunologic response following six months of dose administration. (checkman.com)
  • Results Sixty-six patients were screened and 19 enrolled of whom 14 received at least 3 doses of the vaccine and thus evaluated for the primary immunologic endpoint. (bmj.com)
  • However, with the advent of novel diagnostic technologies, viral respiratory pathogens are increasingly being identified as frequent etiologies of CAP. (medscape.com)
  • The most common viral pathogens recovered from hospitalized patients admitted with CAP include human rhinovirus and influenza . (medscape.com)
  • However, with the advent of novel diagnostic technologies, viral respiratory tract infections are being identified as common etiologies of CAP. (medscape.com)
  • First, a full-length functional ZIKV cDNA clone was engineered as a bacterial artificial chromosome, with each reporter gene under the cap-independent translational control of a cardiovirus-derived internal ribosome entry site inserted downstream of the single open reading frame of the viral genome. (mdpi.com)
  • Lactobacillus rhamnosus has been found to modulate and enhance immunity and fortify intestinal immunologic barrier function. (unovita.com)
  • [ 6 ] Therefore, additional testing remains necessary to identify the pathogen and to optimize therapy in CAP. (medscape.com)
  • Serologic activity emerged as a hallmark of CB-CAPs positivity. (bmj.com)
  • Serologic markers of disease activity including elevated levels of anti-dsDNA and decreased C3 or C4 also tracked with CB-CAPs positivity (table 2). (bmj.com)
  • CB-CAPs positive patients represent an important subset of patients who are characterized by greater serologic activity and internal organ pathology. (bmj.com)
  • In addition, false-positive test results are observed when nonspecific serologic reactions occur among uninfected persons who have immunologic disturbances or who have had analyses of licensed anti-HIV EIA test kits have found similar or slightly lower sensitivity and specificity (2-5). (cdc.gov)
  • In addition, false-positive test results are observed when nonspecific serologic reactions occur among uninfected persons who have immunologic disturbances or who have had multiple transfusions. (cdc.gov)
  • Aloe Ferox Bitter Caps supports normal, daily, healthy bowel function with a higher concentration of the bitter extract compared to our original formula Whole Leaf Caps. (mcssl.com)
  • In the treatment of warts, a mild irritant reaction, which may render the virus more prone to immunologic stimulation or response, may add to the mechanical removal of infected cells. (brennanspharmacy.com)
  • We conclude that IRV-IPV dMNP did not interfere with each other in triggering an immunologic response and were highly immunogenic in rats. (cdc.gov)
  • In addition, patients with atypical CAP may present with more subtle pulmonary findings, nonlobar infiltrates on radiography, and various extrapulmonary manifestations (eg, diarrhea, otalgia). (medscape.com)
  • When infants develop this significant scalp rash, it's often known as "cradle cap. (thehealthy.com)
  • Numerically more CB-CAPs positive patients had SLEDAI rash and met SLEDAI renal criteria. (bmj.com)
  • A case series of 64 patient-reported outcomes subsequent to use of a silver-threaded cap designed to protect the brain and brain stem from microwave Electrosmog resulted in 90 % reporting "definite" or "strong" changes in their disease symptoms. (springer.com)
  • Further studies are needed to assess the effects of targeted therapeutics and the long-term outcomes of the CB- CAPs positive endotype. (bmj.com)
  • Patients with typical CAP classically present with fever, a productive cough with purulent sputum, dyspnea, and pleuritic chest pain. (medscape.com)
  • The diagnosis of CAPS should be considered in patients with multiorgan failure (dysfunction of three or more organs) who have positive laboratory test results for APS. (msdmanuals.com)
  • CB-CAPs positive patients were younger, but there were no differences in sex, ethnicity, race, or mean length of disease between CB-CAPs positive and negative patients. (bmj.com)
  • Although almost all patients met both SLICC and ACR/EULAR classification criteria, the total ACR/EULAR classification score was greater for CB-CAPs positive patients. (bmj.com)
  • Higher rates of nephritis, serositis, alopecia and hematologic criteria were observed in the CB-CAPs positive patients. (bmj.com)
  • CB-CAPs positive patients were more likely to have positive ANA, anti-Sm, anti-U1RNP, anti-RNP70, anti-C1q and anti-phospholipid antibodies than those who were CB-CAPs negative (table 2). (bmj.com)
  • CB-CAPs positivity could provide both diagnostic and prognostic information with implications for improved disease monitoring. (bmj.com)
  • Flow cytometric analysis of unstimulated platelets from CAPs-exposed mice indicated size and shape changes, and platelets from CAPs-exposed animals had a 54% increase in fibrinogen binding indicative of platelet priming. (cdc.gov)
  • CB-CAPs were determined by flow cytometry. (bmj.com)
  • Typical bacterial pathogens that cause CAP include Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis . (medscape.com)
  • The term "typical" CAP refers to a bacterial pneumonia caused by pathogens such as S pneumoniae , H influenzae , and M catarrhalis . (medscape.com)
  • The new VIM Core will continue to provide our users with state-of-the-art HIV, and now STD, testing in CAP/CLIA laboratories, and continues the aims of providing laboratory support and facilitating AIDS research among CFAR investigators at the University of North Carolina at Chapel Hill, FHI 360, and RTI International. (unccfar.org)
  • Platelets were the only peripheral blood cells that were significantly elevated in number in CAPs-exposed mice. (cdc.gov)
  • Additionally, CB-CAPs positive patient demonstrated evidence of SLE disease activity with significantly higher SLEDAI scores. (bmj.com)
  • Stimulation of platelets by thrombin resulted in up-regulation of LAMP-1 expression in CAPs-exposed animals and an increased microparticle population relative to control animals. (cdc.gov)
  • The fund tracks a market-cap-weighted index of companies in the global nuclear energy industry. (baumaschinen-knell.de)
  • The authors exposed mice to an average of 88.5 microg/m(3) of CAPs in a size range less than 2.5 microm for 6 h/day for 5 days per week for 2 weeks. (cdc.gov)
  • Moreover, the cumulative burden of SLE activity is greater in those with CB-CAPS positivity, as measured by the ACR/EULAR criteria score. (bmj.com)
  • The antigen is also observed to collapse with the vimentin reticulum during the formation of a juxtanuclear cap induced by colchicine treatment. (rupress.org)