Mice inbred cba. Medical search. Frequent questions

The CBA/CaJ (CB) and C57BL/6J (B6) inbred strains of mice were exposed for 1 h to noise intensities between 98 and 119 dB SPL. (cdc.gov)
The inbred C57BL/6J-mice (B6) and hybrid B6D2F1-mice demonstrated extensive permanent threshold shift and subsequent onset of AHL. (cdc.gov)
These mice were subsequently bred onto a C57BL/6 genetic background and obtained by Dr. Ulrich Mueller (The Scripps Research Institute). (mmrrc.org)
There, mice were backcrossed to C57BL/6J inbred mice for more than ten generations prior to sending to the MMRRC. (mmrrc.org)
When maintained as a live colony,hemizygous mice may be bred with wildtype (noncarrier) mice from the colony or with C57BL/6J inbred mice (Jax Stock No. 000664 ). (mmrrc.org)
Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA). (prosci-inc.com)
Work in our laboratory has shown that young adult CBA/J mice are more vulnerable to cochlear noise injury than are similar-aged mice of other well-studied strains such as C57BL/6J (B6). (wustl.edu)
Study Sample: The study included 52 CBA/J, 59 C57BL/6J (B6), and 45 (B6 3 CBA/J) F1 hybrid mice, aged 6 wk at time of noise exposure. (wustl.edu)
HET3 mice used in this program are (F2) offspring of CByB6F1/J and C3D2F1/J (combining BALB/cBy, C57BL/6, C3H, and DBA/2) strains. (jax.org)
J:235854 lists J:27148 as the reference for these mice but then describes them as "B6C3F1" when the mice in the given reference were C57BL/6J mice fostered on C3Hf/Nctr mice. (jax.org)
METHODS: Th0, Th1, and Th2 cell lines specific for the class II MHC molecule H2IAb were adoptively transferred into T cell deficient, syngeneic, diabetic mice before transplantation of fully allogeneic C57BL/10 (H2b) or (CBKxBALB/c)F1 (H2k/d+Kb) islet grafts. (ox.ac.uk)
Mice, Inbred C57BL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
This graph shows the total number of publications written about "Mice, Inbred C57BL" by people in this website by year, and whether "Mice, Inbred C57BL" was a major or minor topic of these publications. (uchicago.edu)
Below are the most recent publications written about "Mice, Inbred C57BL" by people in Profiles. (uchicago.edu)

The segregation pattern of chromosomes 14 and 18 were analysed in recombinant inbred strains of mice developed from KE and CBA/Kw strains. (edu.pl)
Quantitative measure of genetic differences in susceptibility to noise -induced hearing loss in two strains of mice. (cdc.gov)
The current study was designed to determine dose-response curves for NIHL over the ranges of intensities of noise that would characterize the B6 and CB inbred strains of mice. (cdc.gov)
The inbred CBA/CaJ (CB) and hybrid CBB6F1 strains of mice exhibited only temporary threshold shift with rapid recovery after exposure to 110 decibels for 1 or 2 hours, and they exhibited no evidence of any AHL. (cdc.gov)
The findings demonstrated the advantages of using inbred and F1 hybrid strains of mice which are genetically well defined, numerous and readily available. (cdc.gov)
Alveolar chord length (CL) in 34 inbred strains of mice was measured after 6 months of exposure to cigarette smoke. (bvsalud.org)

The percentage of total plasma MM present in the low-molecular-weight fraction did not differ statistically between the CFW and CBA J strains. (psu.edu)

IgG1, IgG2b, and IgG3 titers against diphtheria toxoid (DT), pertussis toxin (PT), filamentous hemagglutinin (FHA), and pertactin (Prn) were measured in mice from 28 different inbred and wild-derived strains vaccinated with an aluminum hydroxide-adjuvanted DTaP vaccine. (bvsalud.org)

Protective immunity to malaria: studies with cloned lines of Plasmodium chabaudi chabaudi in CBA/Ca mice. (ox.ac.uk)

Genetics of age-related hearing loss in mice. (cdc.gov)

Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss. (cdc.gov)
We aimed to expand our knowledge about the variable susceptibility of inbred strains to this model and test for genetic variants associated with this trait. (bvsalud.org)
To that end, we sought to measure differential susceptibility to cigarette smoke-induced emphysema in the mouse, identify genetic loci associated with this quantitative trait, and find homologous human genes associated with COPD. (bvsalud.org)

Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. (lookformedical.com)

The number of LPS- and of lipoprotein-reactive B cells in spleen was dependent upon the age of the mouse. (silverchair.com)

The presence of the BXSB-Y in all of the consomic mice was confirmed by crossing the consomic mice with BXSB females and demonstrating accelerated disease in the male offspring. (aai.org)

the abrupt transition in NIHL between 113 and 116 dB for the CB mice is consistent with an ototraumatic structural injury. (cdc.gov)
The purpose of this study was to test the hypothesis that putative genotypes for age related hearing loss (AHL) may make mice more susceptible to noise induced hearing loss (NIHL). (cdc.gov)

An inbred strain of mouse that is widely used in BIOMEDICAL RESEARCH . (nih.gov)
An inbred strain of mouse. (ouhsc.edu)

No LPS-reactive cells but normal frequencies of lipoprotein-reactive cells were found in C3H/HeJ mice, genetically nonreactive to LPS. (silverchair.com)
The use of induced and spontaneous mutant mice and genetically engineered mice (and combinations thereof) to study cancers and other aging phenotypes to advance improved functional human life spans will involve studies of aging mice. (jax.org)
Increased recognition of expected phenotypes, experimental variables that influence phenotypes and research outcomes, and experimental design options and rationales can maximize the utility of genetically engineered mice (GEM) models to translational research on aging. (jax.org)

The severe-combined immunodeficient (SCID) mice have been exploited as a model for onchocerciasis and are permissive to mf of O. lienalis [ 12 ]. (biomedcentral.com)

Using confocal microscopy we have examined in detail the temporal and spatial pattern of green fluorescent protein expression following sub-retinal injection of recombinant adeno-associated virus (rAAV) in the mouse and have determined the effect of viral titre on the number and type of cells transduced. (nih.gov)

Administering TNF to malaria-infected mice did not cause cerebral symptoms nor breakdown of the blood-brain barrier, which is the hallmark of P. berghei ANKA cerebral malaria and is generally absent in human cerebral malaria. (ox.ac.uk)
It induced more reactive nitrogen intermediates in malaria-infected mice than in normal mice, and appreciably more was in the form of nitrate than was in the form of nitrite. (ox.ac.uk)

CBA/Ca mice may be made tolerant to minor histoincompatible B10.BR skin grafts by treatment with a short course of non-depleting anti-mouse CD4 and CD8 monoclonal antibodies (mAb), during the transplantation period. (ox.ac.uk)

and CBA and A/J. Very similar frequencies are found for lipoprotein-reactive B cells in BALB/c, BALB/c ν/ν, C3H/Tif, and C3H/HeJ mice. (silverchair.com)
Mf of O. ochengi were injected subcutaneously at the nape of Syrian hamsters ( Mesocricetus auratus ) and BALB/c mice. (biomedcentral.com)
The Syrian hamsters were found to be the more permissive to O. ochengi mf as fully viable mf were recovered from them on day 30, compared to BALB/c mice where such mf were recovered on day 15, but not 30. (biomedcentral.com)
The abortion rate could be boosted, however, by ultrasonic noise stress of high abortion rate CBA/J, and preimmunization using BALB/c (H‐2 d ) splenocytes protected. (mcmaster.ca)
A similar boosting of loss in low abortion rate BALB/k mice was ameliorated (albeit not completely) by preimmunization with allogeneic paternal but not syngeneic splenocytes. (mcmaster.ca)

We have successively localized the hph-1 mutation to a congenic interval of 1.6-2.8 Mb, containing the GCH gene encoding GTP cyclohydrolase I (GTP-CH I). We used these data to establish a PCR method for genotyping wild type, hph-1 and heterozygote mice, and found that heterozygote animals have partial tetrahydrobiopterin deficiency. (ox.ac.uk)

Subsequently, mice were immunized with either the purified AS or CB antigens in Freund's complete adjuvant (FCA). (ox.ac.uk)
METHOD: The effects of alloimmunization against paternal strain antigens were tested in pregnant mice subjected to stress. (mcmaster.ca)

RESULTS: Restraint stress boosted the resorption rate assessed on day 13.5 of pregnancy in DBA/2‐mated C3H/HeJ mice with an optimal effect on day 4.5 of pregnancy, and premating alloimmunization greatly reduced the effect. (mcmaster.ca)
A/J mice mated to DBA/2 or C3H/HeJ males showed reduced fertility, perhaps due to failure of pregnancy immediately after the stress, but this was not corrected by alloimmunization with either DBA/2 [class I + class II major histocompatibility complex (MHC) immunogen] or C3H/HeJ (class I MHC immunogen) splenocytes. (mcmaster.ca)

Annotation of mouse strain CBA/J genome assembly provided by GENCODE consortium. (jax.org)
J:259852 Mouse Genome Informatics and the WTSI Mouse Genomes Project, MGI Strain Genome Feature and Gene Model Load. (jax.org)
A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeat expansions in mice. (uchicago.edu)

Accordingly, we evaluated both noise vulnerability and the extent of protection from noise by low-dose KM in 6-wk-old F1 hybrids derived from a B6 3 CBA/J cross. (wustl.edu)
The problem we have been concerned with is to find an in vitro correlate with tumorigenicity in a system of cell hybrids in the mouse. (biologists.com)
Previous studies have demonstrated that the Y chromosome of the BXSB mouse can lead to accelerated autoimmunity in inbred BXSB mice and in F1 hybrids. (aai.org)

The B6-mice had normal auditory evoked brainstem response thresholds from 1 to 2 months of age, but they show gradual progressive elevation of thresholds for high frequencies. (cdc.gov)

MRSA strains successfully colonize the urinary tract of female CBA mice with selective induction of inflammation in the kidneys but not the bladder. (tamu.edu)
Transgenic (GCH-Tg) mice demonstrated selective augmentation of endothelial BH4 levels. (ox.ac.uk)

The analysis was possible owing to the fact that the C-band on chromosomes 14 of the CBA/Kw strain and that of chromosome 18 of the KE strain show size polymorphism: while the CBA/Kw mice have a small sized C-band on chromosome 14, the KE mice show small C-bands on chromosome 18. (edu.pl)
Studies of consomic mice bearing the Y chromosome of the BXSB mouse. (aai.org)
To additionally study the effects of the BXSB-Y, we have studied three sets of Y-consomic mice, NZB.BXSB-Y, NZW.BXSB-Y, and CBA/J.BXSB-Y, each consisting of background genes from the non-BXSB parent and the Y chromosome from the BXSB mouse. (aai.org)

The authors conclude that the major differences observed for permanent threshold shift in the B6 and B6D2F1-mice and the minimal temporary threshold shifts in the CB and CBB6F1-mice support the hypothesis for a major genetic difference among these strains. (cdc.gov)
We found that the CBA/J.BXSB-Y mice showed few differences from control CBA/J males. (aai.org)

Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: Observation of a positive response. (cdc.gov)

LPS-reactive B cells yielding IgM- and IgG-PFC responses could be found in mesenteric lymph nodes, bone marrow, thymus, thoracic duct, and peripheral blood of 6- to 8-wk old mice. (silverchair.com)

The significantly higher urinary GS excretion in CFW mice was accompanied by a 1.6-fold lower urinary γ-glutamyltranspeptidase (γ-GTP) activity in this strain. (psu.edu)
Results: The "threshold" noise exposure duration for NIPTS in F1 hybrid mice was similar to that in CBA/J. Like CBA/J mice, F1 mice were also significantly protected from noise by KM although the protection appeared less robust than in the CBA/J parent strain. (wustl.edu)
SJL mice had significantly lower frequencies of LPS- and of lipoprotein-reactive B cells (1 in approximately 30 B cells). (silverchair.com)
This work demonstrates that the genetic background contributes significantly to the magnitude and longevity of vaccine-induced IgG1, IgG2b, and IgG3 titers in mice. (bvsalud.org)

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. (mmrrc.org)

We have now investigated the importance and mechanisms of BH4 availability in vivo using a novel transgenic mouse model with endothelial-targeted overexpression of the rate-limiting enzyme in BH4 synthesis, guanosine triphosphate-cyclohydrolase I (GTPCH). (ox.ac.uk)
Gene expression of ANT2 is reduced in lung tissue from COPD patients and in a mouse smoking model, and overexpression of ANT1 and ANT2 resulted in enhanced oxidative respiration and ATP flux. (bvsalud.org)
Chronic cigarette smoke exposure in the mouse is a commonly used animal model of COPD. (bvsalud.org)
The current work examines this phenomenon in more detail using CBA/Ca mice receiving rat antimouse CD8 mAbs as a model system. (ox.ac.uk)
The hph-1 ENU-mutant mouse provides a model of tetrahydrobiopterin deficiency for studying hyperphenylalaninaemia, dopa-response dystonia, and vascular dysfunction. (ox.ac.uk)
Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. (ouhsc.edu)
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. (uchicago.edu)

These are independent clonal derivatives of a spontaneous malignant melanoma tumour in the mouse. (biologists.com)

Only homologous challenge of the mice immunized with CB antigen produced statistically significant modification of the initial parasitaemia. (ox.ac.uk)

This strain is commonly used as genetic background for transgenic mouse models. (uchicago.edu)

Mice, Inbred DBA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)

In contrast, NZW.BXSB-Y males had accelerated renal and cardiac disease and early death, resembling that previously reported for (NZW X BXSB)F1 mice. (aai.org)
By contrast, CBA/J and A/J mice proved resistant to abortion boosting by restraint stress. (mcmaster.ca)

Horizontal optokinetic nystagmus (OKN) evoked by a random dot pattern moving at a constant speed around the animal was investigated in wildtype mice and "Weaver" mutants (cerebellar impairment) by means of chronically implanted EOG-electrodes. (nih.gov)

In the periphery, the antigen is found on a few percent of lymph node and not on splenic T cells, and it is absent in nude mice. (jax.org)

Pax2 mutant mice display increase. (unige.ch)
Its absence, as assessed in Pax2(1Neu) mutant mice, results in a two- to threefold increase in the average pancreas volume occupied by the islets in both heterozygous and homozygous mutant mice with a gene-dependent dosage effect. (unige.ch)
Importantly, relative fitness of the MRSA mutant lacking the ACME region is further decreased in mice that receive supplemental copper compared to the parental strain. (tamu.edu)

abstract = "The present studies attempted to identify the mechanism for the elevated urinar excretion rate for methyl mercury (MM) previously reported in CFW Swiss mice. (psu.edu)

Tumor necrosis factor has been reported to generate nitric oxide in vitro, so we have measured levels of this molecule and its products in the plasma of mice after they have received an injection of tumor necrosis factor, lymphotoxin, interleukin-1, gamma interferon, or interleukin-6, all of which have been reported to be increased in malaria. (ox.ac.uk)

In diabetic GCH-Tg mice, superoxide production from the endothelium was markedly reduced compared with that of WT mice, endothelial BH4 levels were maintained despite some oxidative loss of BH4, and NO-mediated vasodilatation was preserved. (ox.ac.uk)
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. (ox.ac.uk)

In WT mice, induction of diabetes with streptozotocin (STZ) increased vascular oxidative stress, resulting in oxidative loss of BH4, forming BH2 and biopterin. (ox.ac.uk)

Founder line B was established and maintained on a mixed B6;CBA genetic background. (mmrrc.org)

The shape of OKN in the homozygotic Weaver mouse was clearly different from that in normal mice. (nih.gov)

Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models. (uchicago.edu)

Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. (ouhsc.edu)

Pathobiology of aging mice and GEM: background strains and experimental design. (jax.org)

NEW METHOD: Here we investigate the animal movement associated with a startle in mouse (CBA/CaJ). (omeka.net)

The CamKII-tTA transgene was designed by Dr. Mark Mayford (Columbia University, New York) with 8.5 kb of the mouse CaMKIIalpha promoter placed upstream of the tetracycline-regulated transactivator (tTA or "Tet-Off") gene (flanked by an artificial intron and splice sites at the 5' end and by a polyadenylation signal from SV40 at the 3' end). (mmrrc.org)

The titers and duration of vaccine-specific IgG subclass responses were different among mouse strains, indicating that genetic factors contribute to this variation. (bvsalud.org)

Purpose: We hypothesize that young CBA/J and B6 mice carry different alleles at unknown loci that mediate their characteristic sensitivities to noise and responses to kanamycin. (wustl.edu)

Previous studies indicated that the B6 mice exhibited permanent threshold shifts (PTS) after 1 h exposure to 110 dB, whereas the CB mice did not exhibit any PTS. (cdc.gov)
Intervention: For experiments aimed at noise vulnerability, B6 and F1 mice were exposed to loud broadband noise (4-45 kHz, 110 dB SPL) for varying durations, and the resulting noise-induced permanent threshold shifts (NIPTSs, measured 2 wk postnoise) were compared with previous data from CBA/J mice. (wustl.edu)

Effects of Depilatory Cream Formulation and Contact Time on Mouse Skin. (uchicago.edu)

These mice are a "Tet-Off" tool that allow the inducible expression of genes in forebrain neurons. (mmrrc.org)

Segregation of mouse hemopoietic progenitor cells using the monoclonal antibody, YBM/42. (ox.ac.uk)

Anatomy2

Organisms7

Diseases5

Chemicals and Drugs1

Phenomena and Processes3

C57BL14

Strains of mice6

Molecular Weight1

Different inbred1

Plasmodium1

Genetics1

Susceptibility3

Species1

Spleen1

Male1

NIHL2

Strain of mouse2

Genetically3

Scid1

Recombinant1

Malaria-infected mice2

Transplantation1

BALB5

Animals1

Antigens2

Pregnancy2

Genome3

Hybrids3

Auditory1

Selective2

Chromosome3

Differences2

Assay1

BONE MARROW1

Significantly4

Females1

Model7

Spontaneous1

Statistically1

Transgenic mouse1

MeSH1

Contrast2

Wildtype1

Splenic1

Mutant3

Abstract1

Plasma1

Endothelial2

Induction1

Genetic background1

Normal mice1

Models1

Humans1

Experimental1

Animal1

Transgene1

Factors1

Loci1

Threshold2

Effects1

Genes1

Segregation1