AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Neoplasm MetastasisLymphatic MetastasisLung NeoplasmsLiver NeoplasmsPancreatic NeoplasmsNeoplasm InvasivenessNeoplasmsSkin NeoplasmsBreast NeoplasmsCell Line, TumorNeoplasm StagingImmunohistochemistryAdenocarcinomaKidney NeoplasmsMelanomaPrognosisColorectal NeoplasmsTumor Markers, BiologicalNeoplasm TransplantationThyroid NeoplasmsNeoplasms, Cystic, Mucinous, and SerousNeoplasms, Multiple PrimaryGene Expression Regulation, NeoplasticCarcinomaMice, NudeNeoplasm Recurrence, LocalRetrospective StudiesStomach NeoplasmsBrain NeoplasmsSpinal NeoplasmsColonic NeoplasmsNeoplasm ProteinsTomography, X-Ray ComputedNeoplasms, ExperimentalLymph NodesProstatic NeoplasmsCarcinoma, PapillaryCell MovementAdenocarcinoma, MucinousNeoplasms, Second PrimaryOvarian NeoplasmsSplenic NeoplasmsFatal OutcomeDNA, NeoplasmDisease ProgressionTreatment OutcomeGastrointestinal NeoplasmsSoft Tissue NeoplasmsSurvival RateMelanoma, ExperimentalNeovascularization, PathologicEye NeoplasmsCarcinoma, Squamous CellMammary Neoplasms, ExperimentalParotid NeoplasmsMuscle NeoplasmsSurvival AnalysisHeart NeoplasmsCarcinoma, Pancreatic DuctalAdenocarcinoma, PapillaryTumor Cells, CulturedAntineoplastic AgentsAntigens, NeoplasmCombined Modality TherapyPeritoneal NeoplasmsMeningeal NeoplasmsBone Marrow NeoplasmsTransplantation, HeterologousAbdominal NeoplasmsMyeloproliferative DisordersAppendiceal NeoplasmsOsteosarcomaLymph Node ExcisionEndocrine Gland NeoplasmsCell ProliferationNeoplasm SeedingHepatectomyTesticular NeoplasmsIntestinal NeoplasmsSkull NeoplasmsMouth NeoplasmsLiver Neoplasms, ExperimentalBile Duct NeoplasmsMice, SCIDSalivary Gland NeoplasmsMammary Neoplasms, AnimalUterine NeoplasmsCystadenomaCarcinoma, Renal CellTongue NeoplasmsFollow-Up StudiesAdenomaRectal NeoplasmsMice, Inbred BALB CNeoplasms, Glandular and EpithelialMandibular NeoplasmsReverse Transcriptase Polymerase Chain ReactionNeoplasms, Connective and Soft TissueEpithelial-Mesenchymal TransitionNeoplasms, Plasma Cell
MalignantRecurrencePrognosisHead and NeckLungTumor growth and metastasisTumorsMelanomaAdenocarcinomaRisk of metastasisPancreasNeuroendocrineNodal MetastasisBrain metastasesOsseous MetastasesCarcinomaSpinalOncologyResectionDistantSystemicBonePrimaryParotidPancreaticHistologicalPatientsDiagnosisSurvivalLymph nodesGlioblastomaBreastOrganPredominantlyCervicalSurgicalThyroidInvasion
Malignant11
  • A malignant neoplasm (abnormal growth) located on the ovaries. (medlineplus.gov)
  • Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). (wikipedia.org)
  • Glioblastoma multiforme is the most common malignant primary central nervous system neoplasm in adults. (hindawi.com)
  • Deuterium oxide (D2O) induces early stress response gene expression and impairs growth and metastasis of experimental malignant melanoma. (cdc.gov)
  • These data demonstrate for the first time that systemic D2O administration impairs growth and metastasis of malignant melanoma through the pharmacological induction of deuterium (2H)-stress. (cdc.gov)
  • Thyroid metastases are not an exceptional finding at autopsy, and they are encountered in 2% to 9% of the patients with malignant neoplasm. (hindawi.com)
  • Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor of uncertain malignant potential, predominantly affecting young adult females. (cytojournal.com)
  • Solid pseudopapillary neoplasm (SPN) is an indolent epithelial tumor with a low malignant potential that occurs predominantly in females with a mean age of 28 years. (cytojournal.com)
  • Therefore, the identification of hypoxia-inducible protein targets responsible for cancer progression, malignant transformation and metastasis is needed for deepening our understanding of OS biology. (nature.com)
  • About 10% are malignant with tendency to form metastases especially to the liver then therapy requires various medical technics. (nel.edu)
  • The cytoplasmic tail of the podoplanin can bind to ezrin, a protein that have been associated with metastasis and lower survival rate in patients with malignant neoplasms. (usp.br)
Recurrence4
  • During follow-up, no patient died of PNENs, two died of other diseases , three had lymph node metastases , and one experienced recurrence after surgical resection. (bvsalud.org)
  • No deaths, tumor progression, lymph node metastases , distant metastases , or recurrence were noted in patients with PNENs ≤ 1 cm (n = 36). (bvsalud.org)
  • It is considered to be a low-grade indolent neoplasm, because of rare recurrence and metastasis. (ispub.com)
  • Three months later, an anterior resection of the rectum was performed because of anastomotic recurrence and pelvic metastasis positioning on the sigmoid mesenterium. (hindawi.com)
Prognosis5
  • Comparison of prognosis between observation and surgical resection groups with small sporadic non-functional pancreatic neuroendocrine neoplasms without distant metastasis. (bvsalud.org)
  • In this study, we observed that the lncRNA-activated by TGF-β (lncRNA-ATB) was upregulated in hepatocellular carcinoma (HCC) metastases and associated with poor prognosis. (nih.gov)
  • Glioblastoma multiforme (GBM) is a common primary central nervous system (CNS) neoplasm in adults with a very aggressive natural history and grim prognosis [ 1 , 2 ]. (hindawi.com)
  • Type II endometrial cancer is described as non-endometrioid, mutant gene (P53,P16, etc.)harbored, which is associated with a higher risk of metastasis and a poor prognosis[ 5 ]. (jcancer.org)
  • Background Metastasis dominates the prognosis of eyelid sebaceous carcinoma (SC). (bmj.com)
Head and Neck1
Lung4
  • Symptoms often are related to breast or lung metastases or lymphoma in a generalized plexus involvement, sometimes with a lower trunk predominance. (medscape.com)
  • The most common causes of NBP are metastatic lesions from breast or lung cancer , and the clinician also should be aware of possible concurrent cervical spine metastases. (medscape.com)
  • We present a very unique case of colon carcinoma metastasis to the right thyroid lobe and lung five years after colon resection, with reoccurrence two years later in the contralateral thyroid lobe. (hindawi.com)
  • However, gastrointestinal and particularly colonic metastases to the thyroid are extremely rare and usually associated with lung and liver metastasis [ 3 ]. (hindawi.com)
Tumor growth and metastasis2
  • Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer. (nih.gov)
  • Moreover, we have examined the efficacy of D2O-based pharmacological intervention in murine models of human melanoma tumor growth and metastasis. (cdc.gov)
Tumors2
  • They are not true neoplasms ( tumors ), but they are invasive, spreading into nearby tissue. (ivis.org)
  • Solid tumors are characterized by intratumoral hypoxia, and hypoxic cells are associated with the transformation to aggressive phenotype and metastasis. (nature.com)
Melanoma1
  • Feasibility of D2O-based chemotherapeutic intervention (drinking water (30% w/w)) was demonstrated in a severe combined immunodeficiency (SCID) mouse melanoma metastasis model using luciferase-expressing A375-Luc2 cells. (cdc.gov)
Adenocarcinoma2
  • Especially for adenocarcinoma the distribution of lymph node metastases has not yet been described in large series. (mdanderson.org)
  • Colon adenocarcinoma metastasized to the thyroid is rare, usually detected years following colectomy, and most commonly is associated with metastasis to organs such as lungs and liver. (hindawi.com)
Risk of metastasis1
  • Primary thyroid neoplasms are far more common than secondary lesions, but in the presence of other history of malignancy, the risk of metastasis is probably higher. (hindawi.com)
Pancreas2
  • The patient then underwent distal pancreatectomy and splenectomy for a presumptive diagnosis of a cystic neoplasm of the pancreas. (medscape.com)
  • Subsequent 18FDG PET-CT revealed metastases to the regional lymph nodes and the liver and suggested the presence of a primary lesion in the tail of the pancreas which was confirmed in EUS. (nel.edu)
Neuroendocrine4
  • The treatment of small (≤ 2 cm), sporadic localized non-functional pancreatic neuroendocrine neoplasms (PNENs) is often controversial. (bvsalud.org)
  • This article provides a guide to the performance and interpretation of 68 Ga-DOTATATE PET/CT and describes its role in the diagnostic algorithm of neuroendocrine neoplasms and its overall utility in their management. (snmjournals.org)
  • Neuroendocrine neoplasms exhibit variable symptomatology, such as tumor mass effects or the biologic consequences of the bioactive amine secretion, frequently delaying diagnosis. (snmjournals.org)
  • Somatostatin receptor (SSR) imaging offers an opportunity to identify receptor-expressing neuroendocrine neoplasms (NENs) ( 2 , 3 ). (snmjournals.org)
Nodal Metastasis6
  • This study aimed to explore risk factors for nodal metastasis and develop a nomogram to predict nodal metastasis in patients with eyelid SC. (bmj.com)
  • Results Forty patients (12.5%) developed nodal metastasis during a median follow-up of 48.0 months, and the median period between the initial treatment and first nodal metastasis was 18.5 months (range 6.0-80.0 months). (bmj.com)
  • The 1-year, 3-year and 5-year nodal metastasis rates were 5.5%, 12.5% and 15.4%, respectively. (bmj.com)
  • A nomogram that integrated these four factors had a C-index of 0.785, demonstrating a strong power in predicting nodal metastasis of eyelid SC. (bmj.com)
  • Conclusions We identified risk factors for nodal metastasis and developed a nomogram to provide individualised estimates of nodal metastasis for eyelid SC patients and guide postoperative management. (bmj.com)
  • The predictors for nodal metastasis of eyelid SC are multifactorial and include a prolonged diagnostic delay, 10 11 involvement of both the upper and lower eyelids, 12 large tumour size, 6 12 13 multicentric origin, 12 diffuse pattern, 11 12 perivascular invasion, 10 a non-lobular pattern, 12 orbital involvement 10 and an advanced T category. (bmj.com)
Brain metastases1
  • The controversy involves whether patients with a limited number of brain metastases should undergo whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS) delivered only to the radiographically visible tumours. (bmj.com)
Osseous Metastases1
  • Osseous metastases from renal cell carcinoma: embolization and surgery for restoration of function. (ajnr.org)
Carcinoma8
  • Aim of the present study is to evaluate the distribution of lymph node metastases in esophageal carcinoma specimens following transthoracic esophagectomy with at least a 2-field lymphadenectomy. (mdanderson.org)
  • Hyalinizing clear cell carcinoma (HCCC) is a neoplasm that predominantly affects the oral cavity in adult females. (ispub.com)
  • Bone metastases from renal cell carcinoma: preoperative embolization. (ajnr.org)
  • A literature search identified 34 reported cases of colon carcinoma metastasis to the thyroid. (hindawi.com)
  • The final pathological report suggested metastasis of colon carcinoma. (hindawi.com)
  • My research interest is utilizing ultrasound for early detection of primary oropharyngeal squamous cell carcinoma and lymph node metastasis in patients who have been exposed to human papilloma virus (HPV 16 and 18). (mdanderson.org)
  • Technical refinement of ultrasound-guided transoral resection of parapharyngeal/retropharyngeal thyroid carcinoma metastases. (mdanderson.org)
  • Acinic cell carcinoma (ACC) accounts for only 1% of all parotid neoplasms. (surgicalneurologyint.com)
Spinal2
Oncology2
  • To disentangle the effects of WBRT on neurocognition from the effects inherent to the underlying disease, we analysed the results from randomised controlled studies of prophylactic cranial irradiation in oncology patients as well as studies where patients with limited cerebral metastasis were randomised to SRS versus SRS+WBRT. (bmj.com)
  • 3 , 4 The management of patients with cerebral metastasis remains a major challenge in general and neurological oncology. (bmj.com)
Resection1
  • The mean overall survival time was 63.2 +/- 7.7 months and survival time was shorter for younger patients with palliative resection, lymph node metastasis and peritoneal nodules. (who.int)
Distant2
  • 1 2 It exhibits locally invasive behaviour and performs regional lymph node and distant organ metastasis, leading to a 1.6%-31.0% disease-specific mortality. (bmj.com)
  • DFSP is an uncommon neoplasm with low metastatic potential, carrying a 2%-5% risk of distant metastasis. (logicalimages.com)
Systemic1
  • The spine is the most frequent area of bone metastasis in patients with systemic neoplastic disease. (bvsalud.org)
Bone2
  • The purpose of this study is to evaluate the effectiveness of the investigational radioisotope Radium-223 in treatment of men with prostate cancer and bone metastases that no longer respond to hormonal treatment. (bayer.com)
  • Embolization of bone metastases. (ajnr.org)
Primary2
  • Less common primary neoplasms may occur and present as limb pain and/or a tender mass, causing radiating paresthesias upon palpation. (medscape.com)
  • The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. (bvsalud.org)
Parotid1
Pancreatic1
  • Based on the potential for a cystic pancreatic neoplasm, this was pursued further with exploratory laparoscopy. (medscape.com)
Histological1
  • Final histological summation reported colonic metastasis to the left lobe of the thyroid. (hindawi.com)
Patients6
  • Thus, these findings suggest that lncRNA-ATB, a mediator of TGF-β signaling, could predispose HCC patients to metastases and may serve as a potential target for antimetastatic therapies. (nih.gov)
  • Metastasis is the leading cause of death for cancer patients. (nottingham.ac.uk)
  • A fundamental question in this debate involves quantifying the effect of WBRT in patients with cerebral metastasis. (bmj.com)
  • However, there are insufficient data to resolve the controversy of upfront WBRT versus SRS in the management of patients with limited cerebral metastases. (bmj.com)
  • 2 Between 9% and 17% of all cancer patients will develop cerebral metastases during their clinical course. (bmj.com)
  • 5 As the population of patients at risk for cancer increases, the number of patients at risk for brain metastasis increases. (bmj.com)
Diagnosis1
  • The median survival time from metastasis diagnosis is short (∼14 months) [ 3 - 5 ]. (hindawi.com)
Survival2
  • Conclusion: TIGER will provide a roadmap of the location of lymph node metastases in relation to tumor histology, tumor location, invasion depth, number of lymph nodes and lymph node metastases, pre-operative diagnostics, neo-adjuvant therapy and survival. (mdanderson.org)
  • Cox analyses were employed to investigate predictors of metastasis-free survival (MFS), and a nomogram was established and validated by the bootstrap method. (bmj.com)
Lymph nodes1
  • Metastases to axillary lymph nodes are commonly and readily confirmed by fine needle aspiration cytology (FNAC). (karger.com)
Glioblastoma1
  • Herein, we report a case of glioblastoma multiforme with metastases to the bones and a poor outcome. (hindawi.com)
Breast1
  • The presence of papillary pattern, particularly in the absence of a clinically detectable breast lesion, should raise the possibility of a metastasis. (karger.com)
Organ2
  • Metastasis is the spread of cancer cells from one area body (such as an organ) to another. (healthdaily.me)
  • There have been reports describing a thyroid mass as an initial presentation and thyroid metastasis without other organ involvement, but these reports are rare [ 5 , 6 ]. (hindawi.com)
Predominantly1
  • In conclusion, obese dogs have several comorbidities, predominantly locomotor changes and neoplasms. (vin.com)
Cervical1
  • I have expertise in evaluating thyroid cancers, parathyroid adenomas, cancers of the oropharynx and larynx, cervical lymphomas, and skin cancer metastases to the neck. (mdanderson.org)
Surgical2
  • Surgical strategy depends on the distribution pattern of nodal metastases but consensus on the extent of lymphadenectomy differs worldwide. (mdanderson.org)
  • Usually these neoplasms are benign and single with surgical excision as a treatment of choice. (nel.edu)
Thyroid2
  • Microscopic metastasis to the thyroid gland is not rare, having been found in 4%-9% of autopsy studies [ 1 ]. (hindawi.com)
  • To the best of our knowledge, metachronous colon metastasis to the thyroid has never been reported previously. (hindawi.com)
Invasion3
  • Globally, lncRNA-ATB promotes the invasion-metastasis cascade. (nih.gov)
  • Cluster analysis will be performed to identify patterns of metastases in relation to tumor location, tumor histology, tumor invasion depth and neoadjuvant therapy. (mdanderson.org)
  • He studied on cancer invasion and metastasis and earned Ph.D. at 1992. (rochester.edu)