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Sequence Homology, Amino AcidAmino Acid SequenceAmino AcidsSequence Homology, Nucleic AcidMolecular Sequence DataCloning, MolecularBase SequenceSequence AlignmentAmino Acid SubstitutionSequence HomologyEscherichia coliDNA, ComplementaryBinding SitesDNAModels, MolecularRestriction MappingMutationProtein Structure, TertiaryGenesProtein ConformationAmino Acids, EssentialRecombinant ProteinsGenes, BacterialAmino Acid MotifsBacterial ProteinsSequence Analysis, DNAAmino Acid Transport SystemsPeptide FragmentsPlasmidsProtein BindingPhylogenyMolecular WeightSpecies SpecificityMutagenesis, Site-DirectedRNA, MessengerSubstrate SpecificityKineticsCell LineNucleic Acid HybridizationConserved SequenceOpen Reading FramesStructure-Activity RelationshipPeptidesRecombinant Fusion ProteinsDNA Restriction EnzymesProteinsCarrier ProteinsGene LibraryElectrophoresis, Polyacrylamide GelProtein Structure, SecondaryDNA, BacterialTranscription, GeneticDNA PrimersPolymerase Chain ReactionMultigene FamilyAmino Acids, AromaticSaccharomyces cerevisiaeLeucineCattleStructural Homology, ProteinAmino Acids, Branched-ChainBlotting, NorthernMembrane ProteinsAmino Acids, SulfurCyanogen BromideTrypsinsrc Homology DomainsChromatography, High Pressure LiquidChromosome MappingTransfectionCodonBlotting, SouthernViral ProteinsPlant ProteinsSequence AnalysisProtein BiosynthesisGene ExpressionGenes, ViralDNA-Binding ProteinsAlanineSequence DeletionMacromolecular SubstancesGenetic Complementation TestSequence Analysis, ProteinMutagenesisBiological EvolutionRepetitive Sequences, Nucleic AcidFungal ProteinsEvolution, MolecularLysineCOS CellsBiological TransportGenes, FungalCrystallography, X-RayChickensCysteineRabbitsRNADNA, ViralTranscription Factors
ProteinsEncodes a proteinGENOMICReceptorsNucleic AciSimilarityResidues in lengthIsolatesTerminusMonomerCDNAMolecularTranscriptionGenetic relatednessNucleotide sequenceReceptorPolypeptidePrecursorPrimersSpeciesAnalysisMutationsHumanFamilyStructuralSignal sequenceDomainsConformationMethionineEnzymeDisplayMice
Proteins6
  • A sequence comparison of piscivorin and other CRISP family proteins suggests that the Glu186 residue is the crucial site for the blocking of the calcium channels. (wikipedia.org)
  • The products of PI 3-kinase activation, PtdIns(3,4,5)P3 and its immediate breakdown product PtdIns(3,4)P2, trigger physiological processes, by interacting with proteins possessing pleckstrin homology (PH) domains. (nih.gov)
  • Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. (rndsystems.com)
  • The specificity of the proteins is determined by the sequences outside the repeats themselves. (embl.de)
  • We chose proteins that include amino and carboxyl extensions as well as proteins that are made up entirely of WD-repeats. (embl.de)
  • They usually appear in multidomain proteins, together with catalytic domains, or other protein binding modules, such as Src homology 3 (SH3), phosphotyrosine binding (PTB) or pleckstrin homology (PH) domains. (lu.se)
Encodes a protein3
GENOMIC3
  • We mined the zebrafish genomic sequence database and identified contigs containing segments of several dopamine receptor genes. (zfin.org)
  • In this study 67 kb of genomic DNA, corresponding to a deletion interval containing at least part of the Kallmann gene, were sequenced. (embl-heidelberg.de)
  • The Human Genome Variation Society (HGVS) has established a sequence variant nomenclature , an international standard used to report variation in genomic, transcript and protein sequences. (ucsc.edu)
Receptors2
  • The sequencing of the human genome lead to the cloning, de-orphanization, and characterization of many novel G protein-coupled receptors. (frontiersin.org)
  • Of these receptors, the latter shares high sequence homology with the family of P2Y purinoreceptors. (frontiersin.org)
Nucleic Aci1
Similarity3
  • A member of the DtxR/MntR family of metalloregulators, ScaR shares sequence similarity with other family members, and many metal-binding residues are conserved. (duke.edu)
  • The degree of similarity between sequences. (usda.gov)
  • The degree of similarity between sequences of amino acids. (bvsalud.org)
Residues in length2
  • The heavy chain of HPlm consists of five repeating triple-disulfide-linked peptide regions, c. 80 amino acid residues in length, termed kringles (K), that are responsible for interactions of HPlg and HPlm with substrates, inhibitors and regulators of HPlg activation. (embl.de)
  • The Src homology 2 (SH2) domains are about 100 residues in length with an average of 28% pairwise residue identity (Pfam code PF00017). (lu.se)
Isolates3
  • Both the N terminus and C terminus were similar intraserotypically with the exception of serotype-4 isolates which could be divided into A and B subgroups on the basis of their C terminus sequences, which were not known previously. (nih.gov)
  • Sequencing of the N gene of TOSV isolates from patients and vectors indicated 87%-88% and 100% homology at the nucleotide and amino acid levels, respectively, compared to the Italian strain. (cdc.gov)
  • Phylogenetic analysis of short polymerase chain reaction (PCR) products from the L segment showed that nucleotide sequences of TOSV isolates from Granada differ significantly from the Italian strain ISS Phl.3 ( 17 ). (cdc.gov)
Terminus8
  • Two parts of the capsid region, N terminus and C terminus, were sequenced. (nih.gov)
  • No. NP_115776), with exception of the C-terminus, which is 12 amino acids shorter in rodents (Figure 1 ). (frontiersin.org)
  • As for all GPCRs, SUCNR1 has an extracellularly located N-terminus, which contains a consensus sequence for N-linked glycosylation at Asn4. (frontiersin.org)
  • One group of the CXC chemokines have the characteristic three amino acid sequence ELR (glutamic acid-leucine-arginine) motif immediately preceding the first cysteine residue near the amino terminus. (rndsystems.com)
  • The carboxy terminus of Spc110p, which binds calmodulin, resides at the central plaque, and the amino terminus resides at the inner plaque from which nuclear microtubules originate. (sdbonline.org)
  • Region I is located at the amino terminus. (sdbonline.org)
  • Overexpression of SPC98 suppresses the temperature sensitivity conferred by mutations in region I but not the phenotypes conferred by mutations in the other two regions, suggesting that the amino terminus of Spc110p is involved in an interaction with the gamma-tubulin complex composed of Spc97p, Spc98p, and Tub4p. (sdbonline.org)
  • The resulting HPlm contains a heavy chain of 561 amino acid residues, originating from the N-terminus of HPlg, doubly disulfide-linked to a light chain of 230 amino acid residues. (embl.de)
Monomer1
CDNA4
  • The nucleotide sequence of piscivorin cDNA spans 1323 bp, containing an open reading frame of 240 codons. (wikipedia.org)
  • The CgPKAR gene and its corresponding cDNA have been cloned and sequenced. (scialert.net)
  • The amino acid sequence of a major human epididymis-specific protein was deduced from the nucleotide sequence of its cloned cDNA. (embl-heidelberg.de)
  • Two candidate exons, identified by multiparameter computer programs, were found in a cDNA encoding a protein of 679 amino acids. (embl-heidelberg.de)
Molecular2
  • The NcCyP has high sequence homology (86%) with the T. gondii (Tg) 18 kDa CyP (C-18) with a calculated molecular weight (Mr.) of 19.4 kDa. (usda.gov)
  • The expression cassette was generated using standard molecular biology methods, and included a T. reesei signal sequence, the endo-1,4-β-xylanase gene, and the Aspergillus nidulans amdS gene as a selectable marker. (fda.gov)
Transcription1
  • A possible function in sperm maturation as indicated by amino acid similarities to extracellular proteinase inhibitors of genital tract mucous secretions is discussed in the context of its tissue-specific transcription. (embl-heidelberg.de)
Genetic relatedness1
  • Studies of amino acid and nucleotide sequences provide useful information about the genetic relatedness of certain species. (usda.gov)
Nucleotide sequence1
  • Nucleotide sequence homology was 99%-100% in TOSV from vectors and patients and 80%-81% compared to the Italian strain ISS Phl.3. (cdc.gov)
Receptor3
  • At the same time, a second and structurally related receptor, GPR99, was shown to be activated by another citric acid cycle intermediate α-ketoglutarate (or oxoglutarate). (frontiersin.org)
  • Sequence analysis revealed a strong homology between the ligand-binding domain (LBD) of the human mineralocorticoid receptor (hMR) and glucocorticoid receptor (hGR). (aspetjournals.org)
  • The hMR activation process is discussed in the light of the hMR-LBD homology model based on the structural data of the human progesterone receptor LBD. (aspetjournals.org)
Polypeptide2
  • The mature form of the zymogen, human plasminogen (HPlg), contains 791 amino acids present in a single polypeptide chain. (embl.de)
  • [ 4 ] It is also important to understand that the same polypeptide sequence can produce many different patterns of interresidue or intraresidue interactions. (medscape.com)
Precursor1
  • Within the first day after chlorella cells treated with TDPH were illuminated, photodestruction of MgPP(E) was observed, and production of the first specific precursor of chlorophyll (Chl), 5-aminolevulinic acid (ALA), in the cells declined. (researchgate.net)
Primers1
  • The psbA gene that encodes the D1 protein of the PSII fraction was isolated from both isoproturon resistant and susceptible biotypes by PCR amplification using specific primers designed from psbA gene sequence for amaranthus given in the database. (weedscience.com)
Species1
  • The best clarification of the relative structures of the mouse and human CFH gene clusters, at the levels of nucleotide and amino acid sequence and the relative homology of CFH and its related genes within the two species, can be found in an article by Hellwage et al. (molvis.org)
Analysis2
  • tauschii into synthetic hexaploid facilitates the analysis of puroindoline sequence polymorphism and other genetic effects on kernel texture, using testing methods designed for hexaploid wheat, such as the Perten single kernel characterization system (SKCS). (cgiar.org)
  • Sequence analysis revealed that CgPKAR contains one intron located at position -475 to -539 from the start codon (ATG). (scialert.net)
Mutations1
  • To dissect the functions of Spc110p, temperature-sensitive mutations were created in the amino and carboxy termini. (sdbonline.org)
Human4
Family2
  • Members of the chemokine family exhibit from 20% to over 90% identity in their predicted amino acid sequences. (rndsystems.com)
  • Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. (peprotech.com)
Structural1
  • The amino acid residues important in these kringle/ligand binding interactions have been proposed by structural determinations, and their relative importance quantified by site-directed mutagenesis experimentation. (embl.de)
Signal sequence1
Domains1
  • SH2 domains mediate intramolecular recognition and intermolecular protein-protein association almost invariably by binding to phosphorylated tyrosine (pY) residues in specific sequence contexts. (lu.se)
Conformation1
  • Native or wild-type quaternary protein structure is usually born from a single translated protein sequence with one ordered conformation with downstream protein interactions. (medscape.com)
Methionine1
Enzyme1
  • The enzyme 2-hydroxychromene-2-carboxylic acid (HCCA) isomerase catalyzes the glutathione (GSH)-dependent interconversion (Keq = 1.5) of HCCA and trans-o-hydroxybenzylidene pyruvic acid (tHBPA) in the naphthalene catabolic pathway of Pseudomonas putida. (nih.gov)
Display1
Mice1
  • TLR3-deficient (TLR3-/-) mice showed reduced responses to polyinosine-polycytidylic acid (poly(I:C)), resistance to the lethal effect of poly(I:C) when sensitized with d-galactosamine (d-GalN), and reduced production of inflammatory cytokines. (nih.gov)