Inhibition of glutathione S-transferases by photoactive calix[4]arene α-ketophosphonic acids (2022) Bioorganic and Medicinal Chemistry Letters, 77, статья № 129019. (org.ua)
MicroM3
Enhancing this component with 5 microM BAY K 8644 exaggerated the effects of hypoxia, and when the component was inhibited (100 microM Cd2+ or 5 microM nifedipine) hypoxic effects were abolished. (nih.gov)
Fluorescence of Fura 2-loaded cells increased when 50 microM extracellular Cd2+ was added and fluorescence of Quin 2-loaded cells decreased. (nih.gov)
TPEN had little effect on fluorescence of Fura 2-loaded GH3 and C6 cells not exposed to Cd2+ but decreased fluorescence of cells that had been incubated with 1-10 microM Cd2+. (nih.gov)
MeSH1
Piromidic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (childrensmercy.org)
Pharmacology1
1 Department of Pharmacology, University of Rochester School of Medicine and Dentistry, New York 14642. (nih.gov)
TOTAL1
This graph shows the total number of publications written about "Piromidic Acid" by people in this website by year, and whether "Piromidic Acid" was a major or minor topic of these publications. (childrensmercy.org)
Beta3
Carvedilol (0.3 mg/kg, iv) produced a significant inhibition of the beta 1 adrenoceptor mediated positive chronotropic response to isoproterenol. (nih.gov)
This same dose of carvedilol also inhibited, but to a lesser degree, the beta 2 adrenoceptor mediated vasodepressor response to salbutamol in pithed rats whose blood pressure was elevated by a constant intravenous infusion of angiotensin II. (nih.gov)
Thus, carvedilol blocks both beta 1 and beta 2 adrenoceptors at antihypertensive doses, with modest selectivity being observed for the beta 1 adrenoceptor subtype. (nih.gov)
Effect1
Carvedilol produced significant inhibition of the alpha 1 adrenoceptor mediated pressor response to cirazoline in the pithed rat, but had no effect on the alpha 2 adrenoceptor mediated pressor response to B-HT 933, suggesting that carvedilol is also an alpha 1 adrenoceptor antagonist at antihypertensive doses. (nih.gov)