• citation needed] Prostacyclin, which has a half-life of 42 seconds, is broken down into 6-keto-PGF1, which is a much weaker vasodilator. (wikipedia.org)
  • Even at physiological pH, prostacyclin can rapidly form the inactive hydration product 6-keto-prostaglandin F1α. (wikipedia.org)
  • Distribution of prostacyclin synthase, 6-ketoprostaglandin F1 alpha, and 15-hydroxy-prostaglandin dehydrogenase in the normal and persistent ductus arteriosus of the dog. (edu.pl)
  • A tendency towards increased plasma 6-keto-prostaglandin F1 alpha concentration and decreased serum thromboxane B2 concentration was found during the period of regular exercise, but prostaglandin E2 concentrations remained unchanged. (nih.gov)
  • The Alcohol can be monitored by changes in plasma levels of prostanoids such as thromboxane, 6-keto prostaglandin F1 alpha, catecholamines, serotonin, cyclic nucleotides such as cyclic adenosine monophosphate-cAMP, cyclic guanosine monophosphate-cGMP, and platelet aggregation post-alcohol [2]. (lupinepublishers.com)
  • 2018, Article ID 6187245, 6 pp. (edu.pl)
  • The increase in plasma 6-keto-prostaglandin F1 alpha concentration was associated with an increase in serum HDL2 cholesterol concentration in the group taking regular exercise. (nih.gov)
  • We describe a highly specific RIA for blood and urine 6-keto-PGF1 alpha, the principal metabolite of PGI2. (psu.edu)
  • Furosemide increases urine 6-keto-prostaglandin F1 alpha. (musc.edu)
  • Significant elevations of blood 6-keto-PGF1 alpha were found in a high proportion of cancer patients with various solid tumor malignancies. (psu.edu)
  • Although glutathione at concentrations up to 1 mM had no effect on explant function, glutathione did prevent the effects of cadmium on 6-keto-PGF1 alpha. (nih.gov)
  • Description: This rabbit polyclonal antibody is specific to 6-Keto-Prostaglandin F1 and is provided as antiserum. (eaglebio.com)
  • Following two 12-h exposures, 6-keto-PGF1 alpha production by placental explants was 74.8 and 39.9% of unexposed tissue values at 40 and 100 microM cadmium, respectively, with no significant effect on TxB2. (nih.gov)
  • The effect of glutathione on placental TxB2 and 6-keto-PGF1 alpha production was also examined. (nih.gov)
  • Endothelin administration plus nitric oxide inhibition reversed this effect, resulting in an increase in myeloperoxidase and 6-keto-prostaglandin F1alpha. (bvsalud.org)