Acute Generalized Exanthematous Pustulosis
Exanthema
Drug Eruptions
Skin Diseases, Vesiculobullous
Erythema
Stevens-Johnson Syndrome
Acquired Hyperostosis Syndrome
Sternocostal Joints
Hyperostosis, Sternocostoclavicular
Sternoclavicular Joint
Psoriasis
Localized acute generalized exanthematous pustulosis with amoxicillin and clavulanic acid. (1/6)
Acute generalized exanthematous pustulosis (AGEP) is a rare skin disorder, characterized by acute development of numerous, pin-head sized, nonfollicular pustules on erythematous skin, with high fever and neutrophilia. The condition is frequently caused by hypersensitivity reaction to drugs or viral infections. Diagnosis is established according to clinical and histological criteria. Herein, we report a 17-year-old girl with localized AGEP related to the use of amoxicillin-clavulanate. (+info)Acute generalized exanthematous pustulosis due to oral use of blue dyes. (2/6)
(+info)A recent update of pharmacogenomics in drug-induced severe skin reactions. (3/6)
In some adverse drug reactions (ADRs), genetic predisposition plays a significant role in pathogenesis, and the skin is the most frequently reported target. These severe cutaneous ADRs include bullous fixed drug eruptions (FDE), acute generalized exanthematous pustulosis (AGEP), drug-induced hypersensitivity syndrome (HSS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). The putative contribution of individual effector cells in drug hypersensitivity is briefly mentioned. To trigger these drug hypersensitivities, certain class I HLA alleles (e.g., HLA-A and HLA-B alleles) and certain class II HLA alleles (e.g., HLA-DR alleles) have been recently found to be the genetic determinants. One of the best characterized examples mentioned in this article is HLA-B*1502 to determine the incidence of carbamazepine-induced SJS. How drugs are processed and presented by these HLA alleles to activate immune responses has been explained by several hypotheses. Further implication of pharmagenomic findings to prevent drug-induced severe skin reactions can be achieved by pre-screening putative risk HLA alleles before using drugs. (+info)Two cases of acute generalized exanthematous pustulosis related to oral terbinafine and an analysis of the clinical reaction pattern. (4/6)
Acute generalized exanthematous pustulosis (AGEP) is a clinical reaction pattern characterized by the rapid appearance of widespread sterile, nonfollicular pustules arising within edematous erythematous skin. This aseptic pustular eruption is commonly accompanied by leukocytosis and fever and usually follows recent administration of oral or parenteral drugs. We report two cases of terbinafine-induced AGEP in male patients. Both patients developed a generalized erythroderma with scaling and pruritic pustules 7 and 14 days following initiation of oral terbinafine. With immediate discontinuation of terbinafine and various treatment protocols, both patients demonstrated recovery followed by skin desquamation during the subsequent weeks. Terbinafine is the most frequently used systemic antimycotic and antifungal medication, reflecting its superior efficacy for dermatophyte infections. Despite the appealing drug profile, an awareness of terbinafine-induced AGEP is important given the 5 percent mortality associated with AGEP. Additionally, distinguishing the characteristics of AGEP from those associated with toxic epidermal necrolysis, Stevens-Johnson syndrome, and generalized pustular psoriasis allows for prompt dermatologic evaluation, accurate diagnosis, and appropriate treatment. (+info)Acute generalized exanthematous pustulosis with multiple organ dysfunction syndrome. (5/6)
(+info)Acute generalized exanthematous pustulosis due to dextromethorphan. (6/6)
Acute generalized exanthematous pustulosis (AGEP) is a rare, severe, pustular, cutaneous reaction. We report a case in which a patient developed AGEP after the intake of 3 different antitussive agents containing dextromethorphan as the only ingredient in common. (+info)Acute Generalized Exanthematous Pustulosis (AGEP) is a severe cutaneous adverse reaction that typically occurs within 48 hours after the initiation of medication. It is characterized by the rapid development of widespread sterile pustules on an erythematous and edematous base, often accompanied by systemic symptoms such as fever and neutrophilia.
The most common triggers for AGEP are antibiotics (such as beta-lactams, macrolides, and fluoroquinolones), antifungals, and calcium channel blockers. The diagnosis of AGEP is based on clinical presentation, histopathological findings, and the exclusion of other causes of pustular eruptions.
The management of AGEP includes immediate discontinuation of the offending medication, supportive care, and sometimes systemic corticosteroids. The prognosis is generally good with most patients recovering within 2 weeks, although recurrences may occur upon re-exposure to the causative agent.
An exanthem is a skin eruption or rash that often occurs as a symptom of various diseases, such as infectious illnesses. It can appear in different forms, including maculopapular (consisting of both macules and papules), vesicular (small fluid-filled blisters), petechial (small purple or red spots caused by bleeding under the skin), or erythematous (reddened). The rash can be localized to certain areas of the body or generalized, covering large parts or the entire body. Exanthems are usually accompanied by other symptoms related to the underlying disease, such as fever, cough, or muscle aches.
A "drug eruption" is a general term used to describe an adverse skin reaction that occurs as a result of taking a medication. These reactions can vary in severity and appearance, and may include symptoms such as rash, hives, itching, redness, blistering, or peeling of the skin. In some cases, drug eruptions can also cause systemic symptoms such as fever, fatigue, or joint pain.
The exact mechanism by which drugs cause eruptions is not fully understood, but it is thought to involve an abnormal immune response to the medication. There are many different types of drug eruptions, including morphilliform rashes, urticaria (hives), fixed drug eruptions, and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), which is a severe and potentially life-threatening reaction.
If you suspect that you are experiencing a drug eruption, it is important to seek medical attention promptly. Your healthcare provider can help determine the cause of the reaction and recommend appropriate treatment. In some cases, it may be necessary to discontinue the medication causing the reaction and switch to an alternative therapy.
Vesiculobullous skin diseases are a group of disorders characterized by the formation of blisters (vesicles) and bullae (larger blisters) on the skin. These blisters form when there is a separation between the epidermis (outer layer of the skin) and the dermis (layer beneath the epidermis) due to damage in the area where they join, known as the dermo-epidermal junction.
There are several types of vesiculobullous diseases, each with its own specific causes and symptoms. Some of the most common types include:
1. Pemphigus vulgaris: an autoimmune disorder where the immune system mistakenly attacks proteins that help to hold the skin together, causing blisters to form.
2. Bullous pemphigoid: another autoimmune disorder, but in this case, the immune system attacks a different set of proteins, leading to large blisters and inflammation.
3. Dermatitis herpetiformis: a skin condition associated with celiac disease, where gluten ingestion triggers an immune response that leads to the formation of itchy blisters.
4. Pemphigoid gestationis: a rare autoimmune disorder that occurs during pregnancy and causes blisters on the abdomen and other parts of the body.
5. Epidermolysis bullosa: a group of inherited disorders where there is a fragile skin structure, leading to blistering and wound formation after minor trauma or friction.
Treatment for vesiculobullous diseases depends on the specific diagnosis and may include topical or systemic medications, such as corticosteroids, immunosuppressants, or antibiotics, as well as wound care and prevention of infection.
Erythema is a term used in medicine to describe redness of the skin, which occurs as a result of increased blood flow in the superficial capillaries. This redness can be caused by various factors such as inflammation, infection, trauma, or exposure to heat, cold, or ultraviolet radiation. In some cases, erythema may also be accompanied by other symptoms such as swelling, warmth, pain, or itching. It is a common finding in many medical conditions and can vary in severity from mild to severe.
Stevens-Johnson Syndrome (SJS) is a rare, serious and potentially life-threatening skin reaction that usually occurs as a reaction to medication but can also be caused by an infection. SJS is characterized by the detachment of the epidermis (top layer of the skin) from the dermis (the layer underneath). It primarily affects the mucous membranes, such as those lining the eyes, mouth, throat, and genitals, causing painful raw areas that are prone to infection.
SJS is considered a severe form of erythema multiforme (EM), another skin condition, but it's much more serious and can be fatal. The symptoms of SJS include flu-like symptoms such as fever, sore throat, and fatigue, followed by a red or purplish rash that spreads and blisters, eventually leading to the detachment of the top layer of skin.
The exact cause of Stevens-Johnson Syndrome is not always known, but it's often triggered by medications such as antibiotics, anti-convulsants, nonsteroidal anti-inflammatory drugs (NSAIDs), and antiretroviral drugs. Infections caused by herpes simplex virus or Mycoplasma pneumoniae can also trigger SJS.
Treatment for Stevens-Johnson Syndrome typically involves hospitalization, supportive care, wound care, and medication to manage pain and prevent infection. Discontinuing the offending medication is crucial in managing this condition. In severe cases, patients may require treatment in a burn unit or intensive care unit.
Acquired hyperostosis syndrome is not a widely recognized medical term, and it may refer to several different conditions that involve abnormal bone growth or hardening. One possible condition that might be referred to as acquired hyperostosis syndrome is diffuse idiopathic skeletal hyperostosis (DISH).
Diffuse idiopathic skeletal hyperostosis is a non-inflammatory condition that affects the spine and other parts of the body. It is characterized by the calcification and ossification of ligaments and entheses, which are the sites where tendons or ligaments attach to bones. This process can lead to the formation of bony spurs or growths, called osteophytes, along the spine and other affected areas.
The exact cause of DISH is not known, but it is more common in older adults, males, and people with certain medical conditions such as diabetes and obesity. The symptoms of DISH can vary widely depending on the severity and location of the bone growths. Some people may experience stiffness, pain, or limited mobility in the affected areas, while others may have no symptoms at all.
It is important to note that there are many other conditions that can cause abnormal bone growth or hardening, so a proper medical evaluation is necessary to determine the underlying cause of any symptoms. If you have concerns about acquired hyperostosis syndrome or any other medical condition, you should speak with your healthcare provider for further guidance.
Osteitis is a medical term that refers to the inflammation of bone tissue. It can occur as a result of various conditions, such as infection (osteomyelitis), trauma, or autoimmune disorders. The symptoms of osteitis may include pain, swelling, warmth, and redness in the affected area, as well as fever and general malaise. Treatment typically involves addressing the underlying cause of the inflammation, which may involve antibiotics for infection or anti-inflammatory medications for other causes. In some cases, surgery may be necessary to remove infected or damaged bone tissue.
The sternocostal joints are the articulations between the sternum (breastbone) and the costal cartilages of the true ribs (the first seven pairs of ribs). Specifically, the manubrium (the superior portion of the sternum) articulates with the second to seventh costal cartilages, while the body of the sternum articulates with the lower costal cartilages of the fifth to seventh ribs. These joints are synovial joints and allow for some degree of movement during respiration, contributing to the expansion and contraction of the thoracic cavity. The primary motion at these joints is a gliding or sliding motion.
Hyperostosis, sternocostoclavicular, is a medical condition characterized by the abnormal thickening and hardening of the bone tissue in the sternocostoclavicular joint and surrounding areas. The sternocostoclavicular joint is where the clavicle (collarbone) meets the sternum (breastbone) and manubrium, and costae (ribs). This condition can result in pain, stiffness, and limited range of motion in the affected area. The exact cause of hyperostosis, sternocostoclavicular, is not fully understood, but it may be associated with trauma, inflammation, or genetic factors. In some cases, this condition may be asymptomatic and only discovered during imaging studies performed for other reasons. Treatment options typically include pain management, physical therapy, and in some cases, surgery to remove the excess bone growth.
The sternoclavicular joint is the joint where the clavicle (collarbone) meets the sternum (breastbone). It is the only joint that connects the upper limb to the trunk of the body. This joint allows for movement in multiple directions, including elevation and depression of the shoulder, as well as some degree of protraction and retraction. The sternoclavicular joint is supported by several ligaments, which provide stability and strength to the joint.
Foot dermatoses refer to various skin conditions that affect the feet. These can include inflammatory conditions like eczema and psoriasis, infectious diseases such as athlete's foot (tinea pedis), fungal infections, bacterial infections, viral infections (like plantar warts caused by HPV), and autoimmune blistering disorders. Additionally, contact dermatitis from irritants or allergens can also affect the feet. Proper diagnosis is essential to determine the best course of treatment for each specific condition.
Suppuration is the process of forming or discharging pus. It is a condition that results from infection, tissue death (necrosis), or injury, where white blood cells (leukocytes) accumulate to combat the infection and subsequently die, forming pus. The pus consists of dead leukocytes, dead tissue, debris, and microbes (bacteria, fungi, or protozoa). Suppuration can occur in various body parts such as the lungs (empyema), brain (abscess), or skin (carbuncle, furuncle). Treatment typically involves draining the pus and administering appropriate antibiotics to eliminate the infection.
Psoriasis is a chronic skin disorder that is characterized by recurrent episodes of red, scaly patches on the skin. The scales are typically silvery-white and often occur on the elbows, knees, scalp, and lower back, but they can appear anywhere on the body. The exact cause of psoriasis is unknown, but it is believed to be related to an immune system issue that causes skin cells to grow too quickly.
There are several types of psoriasis, including plaque psoriasis (the most common form), guttate psoriasis, inverse psoriasis, pustular psoriasis, and erythrodermic psoriasis. The symptoms and severity of the condition can vary widely from person to person, ranging from mild to severe.
While there is no cure for psoriasis, various treatments are available that can help manage the symptoms and improve quality of life. These may include topical medications, light therapy, and systemic medications such as biologics. Lifestyle measures such as stress reduction, quitting smoking, and avoiding triggers (such as certain foods or alcohol) may also be helpful in managing psoriasis.
Hand dermatoses is a general term used to describe various inflammatory skin conditions that affect the hands. These conditions can cause symptoms such as redness, swelling, itching, blistering, scaling, and cracking of the skin on the hands. Common examples of hand dermatoses include:
1. Irritant contact dermatitis: A reaction that occurs when the skin comes into contact with irritants such as chemicals, soaps, or detergents.
2. Allergic contact dermatitis: A reaction that occurs when the skin comes into contact with allergens, such as nickel, rubber, or poison ivy.
3. Atopic dermatitis (eczema): A chronic skin condition characterized by dry, itchy, and inflamed skin.
4. Psoriasis: A chronic skin condition characterized by red, scaly patches that can occur anywhere on the body, including the hands.
5. Dyshidrotic eczema: A type of eczema that causes small blisters to form on the sides of the fingers, palms, and soles of the feet.
6. Lichen planus: An inflammatory skin condition that can cause purple or white patches to form on the hands and other parts of the body.
7. Scabies: A contagious skin condition caused by mites that burrow into the skin and lay eggs, causing intense itching and a rash.
Treatment for hand dermatoses depends on the specific diagnosis and may include topical creams or ointments, oral medications, phototherapy, or avoidance of triggers.
Acute generalized exanthematous pustulosis - Wikipedia
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Category:Acute generalised exanthematous pustulosis pathology - NC Commons
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AGEP11
- Acute generalized exanthematous pustulosis (AGEP) (also known as pustular drug eruption and toxic pustuloderma) is a rare skin reaction that in 90% of cases is related to medication. (wikipedia.org)
- AGEP is an acute drug eruption characterized by numerous small, primarily non-follicular, sterile skin pustules arising within large areas of red swollen skin usually within days of taking an inciting drug. (wikipedia.org)
- Acute generalized exanthematous pustulosis (AGEP) is a rare skin eruption most commonly caused by medications. (nebraska.edu)
- Acute generalized exanthematous pustulosis (AGEP) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. (biomedcentral.com)
- Acute generalized exanthematous pustulosis (AGEP): Characterized by a widespread rash evolving into pustules, AGEP is associated with a prescribed drug in over 90% of cases. (medscape.com)
- AGEP is associated with IL36RN mutations similar to those found in pustular psoriasis, palmoplantar pustulosis, and acrodermatitis continua of Hallopeau, which is not surprising given the similarities in clinical and immunologic features of these diseases. (medscape.com)
- Like GPP (described above), acute generalized exanthematous pustulosis (AGEP), is characterized by a rash and pustules over a large area of the body, typically triggered by antibiotics or other medications. (medlineplus.gov)
- The less dangerous skin disease is acute generalized exanthematous pustulosis (AGEP), which usually resolves itself within two weeks once acetaminophen is stopped. (time.com)
- There have been rare reports of serious life-threatening skin reactions including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP) with symptoms such as skin redness, rash , and blisters . (medicinenet.com)
- The agency cited three published reports in which individuals developed Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), or acute generalized exanthematous pustulosis (AGEP) following administration of acetaminophen, and later showed skin reactions when rechallenged with the drug. (medpagetoday.com)
- Diagnosis and treatment of mesothelioma can induce changes on the skin Acute generalized exanthematic pustulosis (AGEP) after Pemextred (folate antagonist) use Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. (globale-dermatologie.com)
Pustular psoriasis12
- Cutaneous lesions characteristic of psoriasis vulgaris can be present before, during, or after an acute pustular episode, but are not required for diagnosis of pustular psoriasis. (medscape.com)
- Generalized pustular psoriasis is a chronic and relapsing condition that presents with a sudden onset of rash and pustules located on nonacral skin. (medscape.com)
- Generalized pustular psoriasis also commonly presents with systemic symptoms, including fever, pain, and malaise, the severity of which vary case-by-case, as well as psoriasis vulgaris. (medscape.com)
- The annular (or circinate) type is also known as subacute generalized pustular psoriasis. (medscape.com)
- Palmoplantar pustulosis is a localized form of pustular psoriasis and presents with chronic pustular eruptions of the palms and soles. (medscape.com)
- Pregnancy-associated impetigo herpetiformis: Occurring predominately in the third trimester, this is a variant of acute pustular psoriasis that carries an increased risk of subsequent stillbirth or fetal abnormalities. (medscape.com)
- Sneddon-Wilkinson syndrome or subcorneal pustular dermatosis (SCPD): The disease follows a relapsing and remitting course that may develop into generalized pustular psoriasis. (medscape.com)
- Generalized pustular psoriasis (GPP) is a rare, chronic, and severe inflammatory skin disorder characterized by sudden eruption of sterile pustules, often accompanied by systemic inflammation. (springer.com)
- The MEDLINE database was searched via PubMed to retrieve relevant articles on generalized pustular psoriasis (GPP), using appropriate controlled vocabulary. (springer.com)
- More than a dozen IL36RN gene mutations have been found to increase susceptibility to a serious skin disorder called generalized pustular psoriasis (GPP). (medlineplus.gov)
- We have the generalized pustular psoriasis, also known as GPP. (reachmd.com)
- Generalized pustular psoriasis - it is an innate immune inflammation, neutrophilic. (reachmd.com)
Eruption3
- It is characterized by fever and the acute eruption of non-follicular pustules overlying erythrodermic skin. (nebraska.edu)
- however, some cases have also shown extravasated erythrocytes, neutrophils, and eosinophils with mild dermal edema and slight spongiosis Rarely, the pathology can mimic acute generalized pustular dermatosis, bullous drug eruptions (such as erythema multiforme and fixed drug eruption), lichenoid dermatitis, leukocytoclastic vasculitis, or neutrophilic dermatoses (1). (aad.org)
- The differential diagnosis of SDRIFE includes fixed drug eruption, toxic erythema of chemotherapy, acute generalized exanthematous pustulosis, and drug rash with eosinophilia (DRESS). (aad.org)
Palmoplantar2
- For example, palmoplantar pustulosis affects the hands and feet, and acrodermatitis continua of Hallopeau affects the tips of the fingers and toes. (medlineplus.gov)
- And then we have palmoplantar pustulosis. (reachmd.com)
Pustules3
- A Plethora of Pustules: Acute Generalized Exanthematous Pustulosis. (bvsalud.org)
- Sampson MM, Klinkova O, Vitko J, Casanas B. A Plethora of Pustules: Acute Generalized Exanthematous Pustulosis. (moffitt.org)
- Acute generalised exanthematous pustulosis is a severe cutaneous adverse reaction characterised by the rapid development of nonfollicular, sterile pustules on an erythematous base. (medicaldialogues.in)
Bullous1
- The differential diagnosis for SJS/TEN includes erythema multiforme (EM), autoimmune bullous diseases (including linear IgA dermatosis), autoimmune disease (including bullous lupus erythematosus), staphylococcal scalded skin syndrome (SSSS), graft-vs-host disease (GVHD), generalized fixed bullous drug eruption, and acute generalized exanthematous pustulosis (AGEP). (clinicaladvisor.com)
Severe2
- Prophylaxis of venous thromboembolic disease in medical patients with an acute illness (such as acute heart failure, respiratory insufficiency, severe infections or rheumatic diseases) and reduced mobility at increased risk of venous thromboembolism. (medicines.org.uk)
- These meds are used to treat moderate-to-severe acute pain and chronic pain. (kelleycom.com)
Syndrome4
- Epitheloid Granulomatous reaction [Generalized epithelioid granulomatous reaction with myeloproliferative syndrome associated with pleural mesothelioma and Kaposi's sarcoma]. (globale-dermatologie.com)
- The overall objective of the guidelines is to provide up-to-date, evidence-based recommendations for the diagnosis and management of the full spectrum of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and SJS-TEN overlap in adults during the acute phase of the disease. (medscape.com)
- 4. Patients with SAPHO (Synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome. (who.int)
- Life-threatening complications mainly include, but are not limited to, cardiovascular/cytokine driven shock, pulmonary distress syndrome, or acute renal failure. (who.int)
Patients3
- Reserve use of ciprofloxacin for patients with no alternative treatment options for an acute exacerbation of chronic bronchitis or acute sinusitis. (drugs.com)
- Treatment of acute ST-segment elevation myocardial infarction (STEMI) including patients to be managed medically or with subsequent percutaneous coronary intervention (PCI). (medicines.org.uk)
- Because fluoroquinolones, including CIPRO XR, have been associated with serious adverse reactions [see WARNINGS AND PRECAUTIONS ] and for some patients uncomplicated UTI (acute cystitis) is self-limiting, reserve CIPRO XR for treatment of uncomplicated UTIs (acute cystitis) in patients who have no alternative treatment options. (globalrph.com)
Acetaminophen2
- and an estimated 458 deaths due to acute liver failure.2 In fact, acetaminophen is the number one cause of acute liver failure-placing it above viral hepatitis as a cause. (kelleycom.com)
- Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. (drugs.com)
Sinusitis2
Skin1
- 2 Systemic manifestations of this acute skin failure may include pulmonary, renal, and gastrointestinal involvement. (clinicaladvisor.com)
Reactions2
- New Delhi: The Indian Pharmacopoeia Commission (IPC) has recently issued a drug safety alert for the month of September, revealing that Dimethyl Fumarate is linked to adverse drug reaction alopecia and Cefazolin, a cephalosporin antibiotic, is associated with Acute Generalized Exanthematous Pustulosis.This came after preliminary analysis of Adverse Drug Reactions (ADRs) from the. (medicaldialogues.in)
- Following the preliminary analysis of adverse drug reactions (ADRs) from the PvPI database, it is reported that cefazolin is associated with the adverse reaction, Acute Generalized Exanthematous Pustulosis. (medicaldialogues.in)
Shock1
- On initial evaluation, the patient was intubated in the context of an important vasoplegic shock with acute kidney failure. (biomedcentral.com)
Treatment1
- Acute pain is considered necessary, even beneficial-alerting our bodies to danger or injury, and prompting us to protect ourselves or get treatment. (kelleycom.com)
Palmoplantar pustulosis1
- For example, palmoplantar pustulosis affects the hands and feet, and acrodermatitis continua of Hallopeau affects the tips of the fingers and toes. (medlineplus.gov)
Maculopapular2
- Pruritic generalized maculopapular erythematous eruptions were observed over the entire body. (nih.gov)
- Ideally, this patch test will be used to determine the causes of generalized eczema, systemic contact dermatitis, maculopapular rash, acute generalized exanthematous pustulosis, and fixed drug eruption. (news-medical.net)
Fever1
- Typically, within 48 hours of ingesting the causative medication, there is acute onset of fever and pustulosis with leukocytosis. (unboundmedicine.com)
Chronic2
- Also, CIPRO IV is indicated for the treatment of acute exacerbations of chronic bronchitis caused by Moraxella catarrhalis [see Limitation of Use ]. (globalrph.com)
- Chagas disease has an acute phase and a chronic phase. (benznidazoletablets.com)
Fixed drug eruptions1
- Additional case presentations Dr. Michelleti discussed included acute generalized exanthematous pustulosis, drug-induced SCLE, linear IgA bullous dermatitis, and fixed drug eruptions. (dermcast.tv)
Systemic1
- This medicine may cause serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS). (mayoclinic.org)
Drug1
- These findings point, without doubt, to paracetamol as the drug responsible for inducing acute generalized exanthematous pustulosis in this case. (medscape.com)
Kidney1
- These could be symptoms of a serious kidney problem called acute interstitial nephritis. (mayoclinic.org)
Neck1
- A 32-year-old woman, 18 weeks pregnant, presented to the gynecologic emergency room with an acute fine pustular eruption on her neck and back. (medscape.com)
Options1
- This article will review the various types of generalized rashes, corresponding treatment options, and how to best field questions brought to the community pharmacist. (uspharmacist.com)
Variety1
- A community pharmacist may encounter a variety of generalized rashes. (uspharmacist.com)
Risk1
- Risk of acute hypertensive episode. (medscape.com)
Phase2
- In the acute phase, moist dressings and antiseptic solutions can be beneficial. (clinicaladvisor.com)
- The acute phase occurs immediately after infection and may last up to the first few weeks or months of infection. (benznidazoletablets.com)
Determine1
- There are various types of generalized rashes that pharmacists can quickly assess to determine appropriate self-treatment. (uspharmacist.com)