Amnesia
Amnesia, Retrograde
Amnesia, Anterograde
Amnesia, Transient Global
Korsakoff Syndrome
Memory
Alcohol Amnestic Disorder
Retention (Psychology)
Ischemic Attack, Transient
Pyrithiamine
Diencephalon
Scopolamine Hydrobromide
Neuropsychological Tests
Confusion
Unconsciousness
Hippocampus
Temporal Lobe
Autobiography as Topic
Thalamic Diseases
Memory Disorders
Midazolam
Craniocerebral Trauma
Learning
Anisomycin
Mamillary Bodies
Paired-Associate Learning
Magnetic Resonance Imaging
Thiamine Deficiency
Preanesthetic Medication
Recognition (Psychology)
Brain Damage, Chronic
Anterior Thalamic Nuclei
Calcium
Multiple Personality Disorder
Encyclopedias as Topic
Lack of evidence of acute ischemic tissue change in transient global amnesia on single-shot echo-planar diffusion-weighted MRI. (1/30)
BACKGROUND AND PURPOSE: There is uncertainty concerning the etiology of transient global amnesia (TGA). Previous CT and MRI studies have indicated that permanent structural abnormality is rare in TGA. Diffusion-weighted (DW) MRI is very sensitive to early ischemic parenchymal changes and has recently demonstrated embolic infarction in the posterior cerebral artery territory in 2 TGA patients. We report the findings of DW MRI in 8 patients in acute stages of TGA. METHODS: Conventional and echo-planar DW MRI was performed in 2 patients in the active phase and 6 patients in the recovery phase (1 to 8 hours after cessation of anterograde memory dysfunction) of spontaneously occurring TGA. RESULTS: None of the patients showed signs of hyperintensity on DW images or hypointensity on quantitative apparent diffusion coefficient (ADC) maps to suggest regional decreases of water mobility or acute T2 changes on transverse or coronal slices. CONCLUSIONS: We were unable to detect ADC or acute T2 changes with echo-planar DW MRI in patients with TGA, which suggests that mechanisms other than ischemic infarction may cause TGA. We did not identify spreading depression-associated changes of the ADC. Further refinement of MRI sequences may be necessary to detect subtle or transient signal change in brain parenchyma. (+info)Relationship between migraine and cardiac and pulmonary right-to-left shunts. (2/30)
A relationship between migraine with aura and the presence of right-to-left shunts has been reported in two studies. Right-to-left shunts are also associated with some forms of decompression illness. While conducting research in divers with decompression illness, it was our impression that divers with a large shunt often had a history of migraine with aura in everyday life and after dives. Therefore we routinely asked all divers about migraine symptoms. The medical records of the last 200 individuals referred for investigation of decompression illness were reviewed to determine the association between right-to-left shunts and migraine aura after diving, and migraine in daily life unconnected with diving. Migraine with aura in daily life unconnected with diving occurred significantly more frequently in individuals who had a large shunt which was present at rest (38 of 80; 47.5%) compared with those who had a shunt which was smaller or only seen after a Valsalva manoeuvre (four of 40; 10%) or those with no shunt (11 of 80; 13.8%) (P<0.001). Hemiplegic migraine occurred in 10 divers, each of whom had a shunt that was present at rest; in eight of these cases the shunt was large. The prevalence of migraine without aura was similar in all groups. Post-dive migraine aura was significantly more frequent in individuals who had a large shunt present at rest (21 of 80; 26.3%) compared with those who had a shunt that was smaller or only seen after a Valsalva manoeuvre (five of 40; 12.5%) or no shunt (one of 80; 1.3%) (P<0.001). Thus individuals with a large right-to-left shunt have an increased prevalence of migraine with aura in daily life unconnected with diving, and they also have an increased incidence of migraine aura after dives, but only when the dives liberate venous bubbles. These data suggest the possibility that, in some individuals, right-to-left shunts have a role in the aetiology of migraine with aura. The observations suggest that paradoxical gas embolism may precipitate migraine with aura. (+info)Contrast study on cognitive function with MRI and positron emission tomography imaging in transient global amnesia. (3/30)
OBJECTIVE: To study cognitive function and cerebral metabolic changes in patients with transient global amnesia (TGA). METHODS: Three patients with TGA were given mini-mental state examination (MMSE), revised Wechsler memory scale (WMS-R) examination and magnetic resonance imaging (MRI) scans after they had been diagnosed as TGA. Using (18)F labelled deoxyglucose as tracer, patients were given a positron emission tomography (PET) examination at different periods during recovery. RESULTS: No obvious abnormality was found in MMSE and MRI scans in the three patients. However, WMS-R examination and cerebral PET imaging displayed cognitive dysfunction of varying degrees and low metabolism in local areas related to memory in 2 of 3 patients. CONCLUSIONS: In TGA patients, cognitive function and cerebral metabolic levels are closely correlated with duration of symptoms. It is necessary to stop the TGA attack as quickly as possible early time. (+info)Working memory and executive functions in transient global amnesia. (4/30)
Transient global amnesia (TGA) is usually considered to produce a profound impairment of long-term episodic memory, while at the same time sparing working memory. However, this neuropsychological dissociation has rarely been examined in detail. While a few studies have assessed some components of working memory in TGA, the results that have been obtained are far from conclusive. To clarify this issue, we carried out a comprehensive investigation of working memory in 10 patients during a TGA attack. In the first study, we report the results from three patients examined with a battery of neuropsychological tests designed to assess each of the three subcomponents of Baddeley's model of working memory. In a second study, seven different patients underwent neuropsychological investigations that focused specifically on the central executive system, using a protocol derived from a study by Miyake and colleagues. Our findings showed that subcomponents of working memory, such as the phonological loop and visuo-spatial sketch pad, were spared in TGA patients. Specific executive functions that entailed inhibitory control, dual task performance, updating and shifting mechanisms were also found to be normal. However, we found significantly impaired performance for the Brown-Peterson test, and that TGA patients were significantly impaired in the recollection of their episodic memories. They also made reduced numbers of 'remember' compared with 'know' judgments in the episodic memory test several days after TGA. On the basis of our findings, it would appear that the episodic memory deficit during TGA is not related to elementary aspects of executive functioning. Our data also highlight the nature of the cognitive mechanisms involved in the Brown-Peterson task, which may well depend on long-term memory (such as the process of semantic encoding). Lastly, the selective deficit in recollective episodic memories observed in TGA may be principally related to medial temporal lobe abnormalities that have been reported in this syndrome. (+info)The dynamic time course of memory recovery in transient global amnesia. (5/30)
AIMS: To investigate the dynamic time course of transient global amnesia (TGA)--that is, the process of recovery and the interindividual variability--by testing four patients during the day of TGA itself (on three occasions) and at follow up (on two occasions). METHODS: A specially designed protocol focusing on semantic (both conceptual and autobiographical knowledge) and episodic (both anterograde and retrograde components) memory. RESULTS: Every patient showed marked impairment of both anterograde and retrograde episodic memory during the acute phase, with a relative preservation of personal and conceptual semantic knowledge. During the following phase, the authors observed similarities and differences among the patients' patterns of recovery. In general, retrograde amnesia recovered before the anterograde amnesia and anterograde episodic memory was recovered gradually in every case. In contrast, shrinkage of retrograde amnesia was more heterogeneous. In two of the patients, this shrinkage followed a chronological gradient and the most remote events were recovered first. In the two other patients, it depended more on the strength of the trace, and there was no temporal gradient. For the latter, an executive deficit could account for difficulties in accessing both conceptual knowledge and autobiographical memories. CONCLUSIONS: This profile of recovery suggests a "neocortical to medial temporal" process in every case, and the possibility of an additional frontal dysfunction in some cases. Hence, the acute phase seems to be characterised by a common episodic impairment. This variability between subjects appears in the recovery phase with two different patterns of impairment. (+info)Internal jugular vein valve incompetence and intracranial venous anatomy in transient global amnesia. (6/30)
BACKGROUND: Recently a causal relation between internal jugular vein valve incompetence (IJVVI) and transient global amnesia (TGA) has been suggested. IJVVI is postulated to provoke a transient mesiotemporal ischaemia by venous congestion. This mechanism requires a patent venous pathway from the affected IJV through the transverse sinus, confluens, straight sinus (SS), vein of Galen into the basal vein of Rosenthal and the internal cerebral veins. OBJECTIVE: To study IJVVI in TGA patients in relation to the intracranial venous anatomy. METHODS: IJVVI was defined if a repeated Valsalva manoeuvre (VM) led to a retrograde jugular flow detected by extracranial duplex ultrasound. Non-contrast venous MR angiography (MRA) was performed to analyse intracranial drainage patterns of the SS in relation to the side of the IJVVI. SS drainage was differentiated into three groups: predominantly right, left, and bilateral drainage. Ultrasound studies were performed in 25 TGA patients and 85 age matched controls. Twenty patients underwent venous MRA. RESULTS: Sixty eight per cent of patients and 33% of controls showed unilateral or bilateral IJVVI (p = 0.0025). In 36% of patients a TGA preceding VM was reported. Drainage pattern of SS and side of IJVVI corresponded in five of eight patients (63%) with VM and four of 12 patients without VM (33%, p = 0.0994). CONCLUSION: Our study confirms the significantly higher prevalence of IJVVI in TGA patients. However, no specific IJVVI related intracranial venous drainage patterns could be found to further support the hypothesis of a direct causal relation between IJVVI and TGA. (+info)What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases. (7/30)
Since the first reports of transient global amnesia (TGA) were published in 1956, several neuropsychological and functional imaging studies have shed light on different aspects of this neurological syndrome. By establishing diagnostic criteria, Hodges and Warlow (1990b) have made it far easier to identify clinical TGA-related features. However, no comprehensive survey has been yet carried out in order to validate their criteria/findings or provide information about previously unknown features. In the present paper, (i) we review the literature published since Hodges and Warlow's study and seek to characterize the demographic and clinical features of TGA more accurately, (ii) we report 142 personal TGA cases, with supplementary information regarding both episodes and patients, such as precipitating events, associated symptoms and personality, and (iii) we suggest the existence of different groups of TGA patients, on the basis of a hierarchical cluster analysis. This revealed that in women, episodes are mainly associated with an emotional precipitating event, a history of anxiety and a pathological personality. In men, they occur more frequently after a physical precipitating event. In younger patients, a history of headaches may constitute an important risk factor. No link was found with vascular risk factors. The relevance of each of the above-mentioned variables is discussed in the light of our classification. An extensive description of cases from both the literature and our patient population allows us to refine the characterization of clinical TGA features. (+info)Selective affection of hippocampal CA-1 neurons in patients with transient global amnesia without long-term sequelae. (8/30)
The aetiology, pathomechanisms and anatomical correlates of transient global amnesia (TGA) still remain obscure. Recently, focal MR-signal diffusion-weighted imaging (DWI) changes in the hippocampus have been described in patients with TGA, but the exact localization, long term outcome and pathophysiological nature of these lesions still remain unknown. The topography and time course of hippocampal DWI lesions in 41 TGA patients was studied using serial 3 T high-resolution MR-imaging and correlated to clinical and neuropsychometric results. Of these, 29 patients showed 36 DWI lesions with corresponding T(2) lesions in the hippocampus within a time window of 48 h after onset. Almost all lesions (94%; 34/36) were selectively found in the CA-1 sector (Sommer sector) of the hippocampal cornu ammonis. Most DWI lesions (8/10) were already detectable in the peri-acute phase <6 h after onset of symptoms. A follow-up study 4-6 months after the episode did not show evidence for residual structural sequelae of these lesions (n = 20/20). A venous MR angiography of the intracranial dural sinus showed an asymmetric venous drainage in 21/24 (88%) patients. In 11/16 (69%) patients with unilateral lesions, the asymmetry corresponded to the side of the DWI lesion. Significant episodic verbal memory deficits in the acute phase (n = 14/18) were associated with lesions of the dominant hemisphere while impairment of visuospatial memory was associated with lesions of the non-dominant hemisphere. Persistent neuropsychological sequelae were not detected 4-6 months after the episode (n = 16). This is the first prospective study combining high-resolution imaging and neuropsychometry analysing the detailed functional anatomy and outcome of hippocampal DWI/T(2) lesions in TGA supporting the view the TGA being a benign transient disorder. The TGA can be considered a model for a focal transient perturbation of memory circuits in the temporo-mesial region. (+info)Amnesia is a condition characterized by memory loss, which can be temporary or permanent. It may result from brain damage or disease, and it can affect various aspects of memory, such as the ability to recall past events (retrograde amnesia), the ability to form new memories (anterograde amnesia), or both. Amnesia can also affect a person's sense of identity and their ability to learn new skills.
There are several types of amnesia, including:
1. Anterograde amnesia: This type of amnesia affects the ability to form new memories after an injury or trauma. People with anterograde amnesia may have difficulty learning new information and remembering recent events.
2. Retrograde amnesia: Retrograde amnesia affects the ability to recall memories that were formed before an injury or trauma. People with retrograde amnesia may have trouble remembering events, people, or facts from their past.
3. Transient global amnesia: This is a temporary form of amnesia that usually lasts for less than 24 hours. It is often caused by a lack of blood flow to the brain, and it can be triggered by emotional stress, physical exertion, or other factors.
4. Korsakoff's syndrome: This is a type of amnesia that is caused by alcohol abuse and malnutrition. It is characterized by severe memory loss, confusion, and disorientation.
5. Dissociative amnesia: This type of amnesia is caused by psychological factors, such as trauma or stress. People with dissociative amnesia may have trouble remembering important personal information or events that are emotionally charged.
The treatment for amnesia depends on the underlying cause. In some cases, memory may improve over time, while in other cases, it may be permanent. Treatment may involve medication, therapy, or rehabilitation to help people with amnesia cope with their memory loss and develop new skills to compensate for their memory impairments.
Retrograde amnesia is a form of memory loss where an individual cannot recall information, events, or facts from their personal past before a specific point in time. This type of amnesia is caused by damage to the brain, often as a result of head injury, stroke, infection, or certain medical conditions. The extent and duration of retrograde amnesia can vary widely, depending on the severity and location of the brain injury. In some cases, memory function may return over time as the brain heals, while in other cases the memory loss may be permanent.
Anterograde amnesia is a specific type of memory loss where a person has difficulty forming new memories or learning and retaining new information after the onset of the amnesia. It is often caused by damage to certain parts of the brain, such as the hippocampus and surrounding structures, which play a crucial role in the formation of new memories.
In anterograde amnesia, people may have trouble remembering events that occurred after the onset of their memory impairment, while their ability to recall remote memories or those that were formed before the onset of the amnesia is typically preserved. The severity of anterograde amnesia can vary widely, from mild difficulty with learning new information to a complete inability to form any new memories.
Anterograde amnesia can be caused by various factors, including brain injury, infection, stroke, alcohol or drug abuse, seizures, and certain medical conditions such as Wernicke-Korsakoff syndrome, which is often associated with chronic alcoholism. Treatment for anterograde amnesia depends on the underlying cause and may involve medication, rehabilitation, or other interventions to help improve memory function.
Transient global amnesia (TGA) is a sudden, temporary episode of memory loss that cannot be explained by a more common neurological or medical condition. It is characterized by an inability to form new memories (anterograde amnesia) and to recall past events or personal information (retrograde amnesia). These memory gaps typically last for several hours, but may persist for up to 24 hours.
TGA usually affects people over the age of 50 and is more common in men than women. The exact cause of TGA is not known, although it has been associated with various triggers such as emotional stress, physical exertion, sudden immersion in cold water, sexual activity, and medical procedures.
During a TGA episode, individuals often repeat the same questions or statements due to their inability to form new memories. They may also appear confused or disoriented, but they typically remain conscious and maintain their ability to perform familiar tasks. Most people with TGA do not experience any long-term memory loss or other neurological symptoms after the episode resolves.
The diagnosis of TGA is based on the characteristic symptoms, a normal physical examination, and the exclusion of other potential causes of amnesia through medical testing. Treatment for TGA is generally supportive, focusing on reassuring the individual and providing a safe environment during the episode. Recurrent episodes of TGA are uncommon but can occur in some individuals.
Korsakoff syndrome is a neuropsychiatric disorder typically caused by alcohol abuse, specifically thiamine (vitamin B1) deficiency in the brain. It's often associated with Wernicke encephalopathy, and the two together are referred to as Wernicke-Korsakoff syndrome.
The main features of Korsakoff syndrome include severe memory impairment, particularly anterograde amnesia (inability to form new memories), confabulation (making up stories due to gaps in memory), and a lack of insight into their condition. Other cognitive functions like intelligence and perception are usually preserved.
The syndrome is believed to result from damage to the mammillary bodies and other structures in the diencephalon, particularly the thalamus. Treatment involves abstinence from alcohol, thiamine replacement, and a balanced diet. The prognosis varies but often includes some degree of permanent memory impairment.
In the context of medical and clinical neuroscience, memory is defined as the brain's ability to encode, store, retain, and recall information or experiences. Memory is a complex cognitive process that involves several interconnected regions of the brain and can be categorized into different types based on various factors such as duration and the nature of the information being remembered.
The major types of memory include:
1. Sensory memory: The shortest form of memory, responsible for holding incoming sensory information for a brief period (less than a second to several seconds) before it is either transferred to short-term memory or discarded.
2. Short-term memory (also called working memory): A temporary storage system that allows the brain to hold and manipulate information for approximately 20-30 seconds, although this duration can be extended through rehearsal strategies. Short-term memory has a limited capacity, typically thought to be around 7±2 items.
3. Long-term memory: The memory system responsible for storing large amounts of information over extended periods, ranging from minutes to a lifetime. Long-term memory has a much larger capacity compared to short-term memory and is divided into two main categories: explicit (declarative) memory and implicit (non-declarative) memory.
Explicit (declarative) memory can be further divided into episodic memory, which involves the recollection of specific events or episodes, including their temporal and spatial contexts, and semantic memory, which refers to the storage and retrieval of general knowledge, facts, concepts, and vocabulary, independent of personal experience or context.
Implicit (non-declarative) memory encompasses various forms of learning that do not require conscious awareness or intention, such as procedural memory (skills and habits), priming (facilitated processing of related stimuli), classical conditioning (associative learning), and habituation (reduced responsiveness to repeated stimuli).
Memory is a crucial aspect of human cognition and plays a significant role in various aspects of daily life, including learning, problem-solving, decision-making, social interactions, and personal identity. Memory dysfunction can result from various neurological and psychiatric conditions, such as dementia, Alzheimer's disease, stroke, traumatic brain injury, and depression.
Alcohol Amnestic Disorder is not listed as a separate disorder in the current edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), which is used by mental health professionals to diagnose mental conditions. However, it was previously included in earlier editions as a subtype of Amnestic Disorder due to the effects of substance use or exposure to toxins.
Alcohol Amnestic Disorder is characterized by significant memory impairment that is directly caused by alcohol consumption. This disorder can result in anterograde amnesia, which is the inability to form new memories after drinking, and/or retrograde amnesia, which involves forgetting previously learned information or personal experiences.
The diagnosis of Alcohol Amnestic Disorder typically requires a comprehensive medical and neuropsychological evaluation to determine the extent and nature of memory impairment, as well as to rule out other potential causes for cognitive decline. Treatment usually involves a combination of abstinence from alcohol, pharmacotherapy, and psychosocial interventions to address substance use disorder and any co-occurring mental health conditions.
A Transient Ischemic Attack (TIA), also known as a "mini-stroke," is a temporary period of symptoms similar to those you'd get if you were having a stroke. A TIA doesn't cause permanent damage and is often caused by a temporary decrease in blood supply to part of your brain, which may last as little as five minutes.
Like an ischemic stroke, a TIA occurs when a clot or debris blocks blood flow to part of your nervous system. However, unlike a stroke, a TIA doesn't leave lasting damage because the blockage is temporary.
Symptoms of a TIA can include sudden onset of weakness, numbness or paralysis in your face, arm or leg, typically on one side of your body. You could also experience slurred or garbled speech, or difficulty understanding others. Other symptoms can include blindness in one or both eyes, dizziness, or a severe headache with no known cause.
Even though TIAs usually last only a few minutes, they are a serious condition and should not be ignored. If you suspect you or someone else is experiencing a TIA, seek immediate medical attention. TIAs can be a warning sign that a full-blown stroke is imminent.
"Mental recall," also known as "memory recall," refers to the ability to retrieve or bring information from your memory storage into your conscious mind, so you can think about, use, or apply it. This process involves accessing and retrieving stored memories in response to certain cues or prompts. It is a fundamental cognitive function that allows individuals to remember and recognize people, places, events, facts, and experiences.
In the context of medical terminology, mental recall may be used to assess an individual's cognitive abilities, particularly in relation to memory function. Impairments in memory recall can be indicative of various neurological or psychological conditions, such as dementia, Alzheimer's disease, or amnesia.
Avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It is a form of learning that occurs when an organism changes its behavior to avoid a negative outcome or situation. This can be seen in both animals and humans, and it is often studied in the field of psychology and neuroscience.
In avoidance learning, the individual learns to associate a particular cue or stimulus with the unpleasant experience. Over time, they learn to perform an action to escape or avoid the cue, thereby preventing the negative outcome from occurring. For example, if a rat receives an electric shock every time it hears a certain tone, it may eventually learn to press a lever to turn off the tone and avoid the shock.
Avoidance learning can be adaptive in some situations, as it allows individuals to avoid dangerous or harmful stimuli. However, it can also become maladaptive if it leads to excessive fear or anxiety, or if it interferes with an individual's ability to function in daily life. For example, a person who has been attacked may develop a phobia of public places and avoid them altogether, even though this limits their ability to engage in social activities and live a normal life.
In summary, avoidance learning is a type of conditioning in which an individual learns to act in a certain way to avoid experiencing an unpleasant or aversive stimulus. It can be adaptive in some situations but can also become maladaptive if it leads to excessive fear or anxiety or interferes with daily functioning.
Pyrithiamine is not typically considered a medical term, but it is a chemical compound that has been used in scientific research. It's an antivitamin, specifically an analog of thiamine (vitamin B1), which means it can interfere with the metabolism of thiamine in the body.
Here's a more specific definition from a biochemical perspective:
Pyrithiamine is a synthetic organic compound with the formula C6H7N2O2S. It is an analog of thiamine, where the aminomethyl group of thiamine is replaced by a pyridine ring. This structural modification makes pyrithiamine unable to act as a vitamin, but it can still interact with the enzymes and transport proteins involved in thiamine metabolism. As a result, pyrithiamine has been used as a tool to study thiamine deficiency and its effects on various organisms, including mammals.
Please note that pyrithiamine is not a term commonly used in clinical medicine or patient care. If you have any concerns about vitamins, nutrition, or health-related topics, it's best to consult a healthcare professional for accurate information and advice tailored to your specific situation.
The diencephalon is a term used in anatomy to refer to the part of the brain that lies between the cerebrum and the midbrain. It includes several important structures, such as the thalamus, hypothalamus, epithalamus, and subthalamus.
The thalamus is a major relay station for sensory information, receiving input from all senses except smell and sending it to the appropriate areas of the cerebral cortex. The hypothalamus plays a crucial role in regulating various bodily functions, including hunger, thirst, body temperature, and sleep-wake cycles. It also produces hormones that regulate mood, growth, and development.
The epithalamus contains the pineal gland, which produces melatonin, a hormone that helps regulate sleep-wake cycles. The subthalamus is involved in motor control and coordination.
Overall, the diencephalon plays a critical role in integrating sensory information, regulating autonomic functions, and modulating behavior and emotion.
Scopolamine hydrobromide is a synthetic anticholinergic drug, which means it blocks the action of acetylcholine, a neurotransmitter in the nervous system. It is primarily used for its anti-motion sickness and anti-nausea effects. It can also be used to help with symptoms of Parkinson's disease, such as muscle stiffness and tremors.
In medical settings, scopolamine hydrobromide may be administered as a transdermal patch, which is placed behind the ear to allow for slow release into the body over several days. It can also be given as an injection or taken orally in the form of tablets or liquid solutions.
It's important to note that scopolamine hydrobromide can have various side effects, including dry mouth, blurred vision, dizziness, and drowsiness. It may also cause confusion, especially in older adults, and should be used with caution in patients with glaucoma, enlarged prostate, or certain heart conditions.
Neuropsychological tests are a type of psychological assessment that measures cognitive functions, such as attention, memory, language, problem-solving, and perception. These tests are used to help diagnose and understand the cognitive impact of neurological conditions, including dementia, traumatic brain injury, stroke, Parkinson's disease, and other disorders that affect the brain.
The tests are typically administered by a trained neuropsychologist and can take several hours to complete. They may involve paper-and-pencil tasks, computerized tasks, or interactive activities. The results of the tests are compared to normative data to help identify any areas of cognitive weakness or strength.
Neuropsychological testing can provide valuable information for treatment planning, rehabilitation, and assessing response to treatment. It can also be used in research to better understand the neural basis of cognition and the impact of neurological conditions on cognitive function.
Confusion is a state of bewilderment or disorientation in which a person has difficulty processing information, understanding their surroundings, and making clear decisions. It can be caused by various medical conditions such as infections, brain injury, stroke, dementia, alcohol or drug intoxication or withdrawal, and certain medications. Confusion can also occur in older adults due to age-related changes in the brain.
In medical terms, confusion is often referred to as "acute confusional state" or "delirium." It is characterized by symptoms such as difficulty paying attention, memory loss, disorientation, hallucinations, and delusions. Confusion can be a serious medical condition that requires immediate evaluation and treatment by a healthcare professional.
Unconsciousness is a state of complete awareness where a person is not responsive to stimuli and cannot be awakened. It is often caused by severe trauma, illness, or lack of oxygen supply to the brain. In medical terms, it is defined as a lack of response to verbal commands, pain, or other stimuli, indicating that the person's brain is not functioning at a level necessary to maintain wakefulness and awareness.
Unconsciousness can be described as having different levels, ranging from drowsiness to deep coma. The causes of unconsciousness can vary widely, including head injury, seizure, stroke, infection, drug overdose, or lack of oxygen supply to the brain. Depending on the cause and severity, unconsciousness may last for a few seconds or continue for an extended period, requiring medical intervention and treatment.
The hippocampus is a complex, curved formation in the brain that resembles a seahorse (hence its name, from the Greek word "hippos" meaning horse and "kampos" meaning sea monster). It's part of the limbic system and plays crucial roles in the formation of memories, particularly long-term ones.
This region is involved in spatial navigation and cognitive maps, allowing us to recognize locations and remember how to get to them. Additionally, it's one of the first areas affected by Alzheimer's disease, which often results in memory loss as an early symptom.
Anatomically, it consists of two main parts: the Ammon's horn (or cornu ammonis) and the dentate gyrus. These structures are made up of distinct types of neurons that contribute to different aspects of learning and memory.
The temporal lobe is one of the four main lobes of the cerebral cortex in the brain, located on each side of the head roughly level with the ears. It plays a major role in auditory processing, memory, and emotion. The temporal lobe contains several key structures including the primary auditory cortex, which is responsible for analyzing sounds, and the hippocampus, which is crucial for forming new memories. Damage to the temporal lobe can result in various neurological symptoms such as hearing loss, memory impairment, and changes in emotional behavior.
An autobiography is a type of literature that describes the personal life experiences of an individual, written by that individual. It typically includes details about their upbringing, education, career, relationships, and other significant events in their life. The author may also reflect on their thoughts, feelings, and motivations during these experiences, providing insight into their personality and character.
Autobiographies can serve various purposes, such as sharing one's story with others, leaving a legacy for future generations, or exploring one's personal growth and development. They can be written in different styles, from straightforward and factual to introspective and reflective.
It is important to note that autobiographies are not always entirely accurate, as memory can be selective or distorted. Additionally, some individuals may choose to embellish or exaggerate certain aspects of their lives for dramatic effect or to protect the privacy of others. Nonetheless, autobiographies remain a valuable source of information about an individual's life and experiences.
Thalamic diseases refer to conditions that affect the thalamus, which is a part of the brain that acts as a relay station for sensory and motor signals to the cerebral cortex. The thalamus plays a crucial role in regulating consciousness, sleep, and alertness. Thalamic diseases can cause a variety of symptoms depending on the specific area of the thalamus that is affected. These symptoms may include sensory disturbances, motor impairment, cognitive changes, and altered levels of consciousness. Examples of thalamic diseases include stroke, tumors, multiple sclerosis, infections, and degenerative disorders such as dementia and Parkinson's disease. Treatment for thalamic diseases depends on the underlying cause and may include medications, surgery, or rehabilitation therapy.
Memory disorders are a category of cognitive impairments that affect an individual's ability to acquire, store, retain, and retrieve memories. These disorders can be caused by various underlying medical conditions, including neurological disorders, psychiatric illnesses, substance abuse, or even normal aging processes. Some common memory disorders include:
1. Alzheimer's disease: A progressive neurodegenerative disorder that primarily affects older adults and is characterized by a decline in cognitive abilities, including memory, language, problem-solving, and decision-making skills.
2. Dementia: A broader term used to describe a group of symptoms associated with a decline in cognitive function severe enough to interfere with daily life. Alzheimer's disease is the most common cause of dementia, but other causes include vascular dementia, Lewy body dementia, and frontotemporal dementia.
3. Amnesia: A memory disorder characterized by difficulties in forming new memories or recalling previously learned information due to brain damage or disease. Amnesia can be temporary or permanent and may result from head trauma, stroke, infection, or substance abuse.
4. Mild cognitive impairment (MCI): A condition where an individual experiences mild but noticeable memory or cognitive difficulties that are greater than expected for their age and education level. While some individuals with MCI may progress to dementia, others may remain stable or even improve over time.
5. Korsakoff's syndrome: A memory disorder often caused by alcohol abuse and thiamine deficiency, characterized by severe short-term memory loss, confabulation (making up stories to fill in memory gaps), and disorientation.
It is essential to consult a healthcare professional if you or someone you know experiences persistent memory difficulties, as early diagnosis and intervention can help manage symptoms and improve quality of life.
Midazolam is a medication from the class of drugs known as benzodiazepines. It works by enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA), which has a calming effect on the brain and nervous system. Midazolam is often used for its sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties.
Medically, midazolam is used for various purposes, including:
1. Preoperative medication (sedation before surgery)
2. Procedural sedation (for minor surgical or diagnostic procedures)
3. Treatment of seizures (status epilepticus)
4. Sedation in critically ill patients
5. As an adjunct to anesthesia during surgeries
6. Treatment of alcohol withdrawal symptoms
7. To induce amnesia for certain medical or dental procedures
Midazolam is available in various forms, such as tablets, intravenous (IV) solutions, and intranasal sprays. It has a rapid onset of action and a short duration, making it suitable for brief, intermittent procedures. However, midazolam can cause side effects like drowsiness, confusion, respiratory depression, and memory impairment. Therefore, its use should be carefully monitored by healthcare professionals.
Craniocerebral trauma, also known as traumatic brain injury (TBI), is a type of injury that occurs to the head and brain. It can result from a variety of causes, including motor vehicle accidents, falls, sports injuries, violence, or other types of trauma. Craniocerebral trauma can range in severity from mild concussions to severe injuries that cause permanent disability or death.
The injury typically occurs when there is a sudden impact to the head, causing the brain to move within the skull and collide with the inside of the skull. This can result in bruising, bleeding, swelling, or tearing of brain tissue, as well as damage to blood vessels and nerves. In severe cases, the skull may be fractured or penetrated, leading to direct injury to the brain.
Symptoms of craniocerebral trauma can vary widely depending on the severity and location of the injury. They may include headache, dizziness, confusion, memory loss, difficulty speaking or understanding speech, changes in vision or hearing, weakness or numbness in the limbs, balance problems, and behavioral or emotional changes. In severe cases, the person may lose consciousness or fall into a coma.
Treatment for craniocerebral trauma depends on the severity of the injury. Mild injuries may be treated with rest, pain medication, and close monitoring, while more severe injuries may require surgery, intensive care, and rehabilitation. Prevention is key to reducing the incidence of craniocerebral trauma, including measures such as wearing seat belts and helmets, preventing falls, and avoiding violent situations.
In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.
For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.
Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.
Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.
In the context of medicine and healthcare, learning is often discussed in relation to learning abilities or disabilities that may impact an individual's capacity to acquire, process, retain, and apply new information or skills. Learning can be defined as the process of acquiring knowledge, understanding, behaviors, and skills through experience, instruction, or observation.
Learning disorders, also known as learning disabilities, are a type of neurodevelopmental disorder that affects an individual's ability to learn and process information in one or more areas, such as reading, writing, mathematics, or reasoning. These disorders are not related to intelligence or motivation but rather result from differences in the way the brain processes information.
It is important to note that learning can also be influenced by various factors, including age, cognitive abilities, physical and mental health status, cultural background, and educational experiences. Therefore, a comprehensive assessment of an individual's learning abilities and needs should take into account these various factors to provide appropriate support and interventions.
Anisomycin is an antibiotic derived from the bacterium Streptomyces griseolus. It is a potent inhibitor of protein synthesis and has been found to have antitumor, antiviral, and immunosuppressive properties. In medicine, it has been used experimentally in the treatment of some types of cancer, but its use is limited due to its significant side effects, including neurotoxicity.
In a medical or scientific context, 'anisomycin' refers specifically to this antibiotic compound and not to any general concept related to aniso- (meaning "unequal" or "asymmetrical") or -mycin (suffix indicating a bacterial antibiotic).
The mamillary bodies are a pair of small, round structures located in the hypothalamus region of the brain. They play a crucial role in the limbic system, which is involved in emotions, memory, and learning. Specifically, the mamillary bodies are part of the circuit that forms the Papez circuit, a neural network responsible for memory and cognitive functions.
The mamillary bodies receive inputs from several brain regions, including the hippocampus, anterior thalamic nuclei, and cingulate gyrus. They then project this information to the thalamus, which in turn sends it to the cerebral cortex for further processing.
Damage to the mamillary bodies can result in memory impairment, as seen in patients with Korsakoff's syndrome, a condition often associated with chronic alcohol abuse.
Paired-associate learning is a form of implicit or non-declarative memory task that involves learning and remembering the association between two unrelated items, such as a word and an object, or a taste and a sound. In this type of learning, the individual learns to respond appropriately when presented with one member of the pair, due to its association with the other member. This process is often used in various fields including cognitive psychology, neuroscience, and education to study memory, learning, and brain function.
Medical Definition:
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.
Thiamine deficiency, also known as beriberi, is a condition that results from inadequate intake or impaired absorption of thiamine (vitamin B1), which is essential for energy metabolism and nerve function. This deficiency can lead to various symptoms such as peripheral neuropathy, muscle weakness, heart failure, and in severe cases, Wernicke-Korsakoff syndrome, a neurological disorder associated with alcoholism. Thiamine deficiency is commonly found in populations with poor nutrition, alcohol dependence, and gastrointestinal disorders affecting nutrient absorption.
Preanesthetic medication, also known as premedication, refers to the administration of medications before anesthesia to help prepare the patient for the upcoming procedure. These medications can serve various purposes, such as:
1. Anxiolysis: Reducing anxiety and promoting relaxation in patients before surgery.
2. Amnesia: Causing temporary memory loss to help patients forget the events leading up to the surgery.
3. Analgesia: Providing pain relief to minimize discomfort during and after the procedure.
4. Antisialagogue: Decreasing saliva production to reduce the risk of aspiration during intubation.
5. Bronchodilation: Relaxing bronchial smooth muscles, which can help improve respiratory function in patients with obstructive lung diseases.
6. Antiemetic: Preventing or reducing the likelihood of postoperative nausea and vomiting.
7. Sedation: Inducing a state of calmness and drowsiness to facilitate a smooth induction of anesthesia.
Common preanesthetic medications include benzodiazepines (e.g., midazolam), opioids (e.g., fentanyl), anticholinergics (e.g., glycopyrrolate), and H1-antihistamines (e.g., diphenhydramine). The choice of preanesthetic medication depends on the patient's medical history, comorbidities, and the type of anesthesia to be administered.
Chronic brain damage is a condition characterized by long-term, persistent injury to the brain that results in cognitive, physical, and behavioral impairments. It can be caused by various factors such as trauma, hypoxia (lack of oxygen), infection, toxic exposure, or degenerative diseases. The effects of chronic brain damage may not be immediately apparent and can worsen over time, leading to significant disability and reduced quality of life.
The symptoms of chronic brain damage can vary widely depending on the severity and location of the injury. They may include:
* Cognitive impairments such as memory loss, difficulty concentrating, trouble with problem-solving and decision-making, and decreased learning ability
* Motor impairments such as weakness, tremors, poor coordination, and balance problems
* Sensory impairments such as hearing or vision loss, numbness, tingling, or altered sense of touch
* Speech and language difficulties such as aphasia (problems with understanding or producing speech) or dysarthria (slurred or slow speech)
* Behavioral changes such as irritability, mood swings, depression, anxiety, and personality changes
Chronic brain damage can be diagnosed through a combination of medical history, physical examination, neurological evaluation, and imaging studies such as MRI or CT scans. Treatment typically focuses on managing symptoms and maximizing function through rehabilitation therapies such as occupational therapy, speech therapy, and physical therapy. In some cases, medication or surgery may be necessary to address specific symptoms or underlying causes of the brain damage.
Verbal learning is a type of learning that involves the acquisition, processing, and retrieval of information presented in a verbal or written form. It is often assessed through tasks such as list learning, where an individual is asked to remember a list of words or sentences after a single presentation or multiple repetitions. Verbal learning is an important aspect of cognitive functioning and is commonly evaluated in neuropsychological assessments to help identify any memory or learning impairments.
The anterior thalamic nuclei are a group of nuclei in the thalamus, which is a part of the brain. The thalamus serves as a relay station for sensory and motor signals to the cerebral cortex. The anterior thalamic nuclei, specifically, are involved in various functions such as memory, navigation, and arousal. They receive inputs from the hippocampus and other limbic structures and project to the cingulate gyrus and other areas of the cerebral cortex. The anterior thalamic nuclei have been implicated in several neurological and psychiatric conditions, including epilepsy, Alzheimer's disease, and schizophrenia.
Calcium is an essential mineral that is vital for various physiological processes in the human body. The medical definition of calcium is as follows:
Calcium (Ca2+) is a crucial cation and the most abundant mineral in the human body, with approximately 99% of it found in bones and teeth. It plays a vital role in maintaining structural integrity, nerve impulse transmission, muscle contraction, hormonal secretion, blood coagulation, and enzyme activation.
Calcium homeostasis is tightly regulated through the interplay of several hormones, including parathyroid hormone (PTH), calcitonin, and vitamin D. Dietary calcium intake, absorption, and excretion are also critical factors in maintaining optimal calcium levels in the body.
Hypocalcemia refers to low serum calcium levels, while hypercalcemia indicates high serum calcium levels. Both conditions can have detrimental effects on various organ systems and require medical intervention to correct.
Multiple Personality Disorder (MPD) is currently referred to as Dissociative Identity Disorder (DID) in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). It's a complex dissociative disorder involving the presence of two or more distinct identities or personality states that recurrently take control of an individual's behavior.
In DID, each identity, or 'alter', may have its own unique name, personal history, characteristics, and mannerisms. The switching between these identities is often triggered by stressful situations or traumatic memories.
This disorder typically develops as a coping mechanism in response to severe, prolonged trauma during early childhood, such as emotional, physical, or sexual abuse. It's important to note that this condition should be diagnosed and managed by mental health professionals with expertise in dissociative disorders.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Venous valves are one-way flaps made of thin, flexible tissue that lie inside your veins. They allow blood to flow towards the heart but prevent it from flowing backward. These valves are especially important in the veins of the legs, where they help to counteract the force of gravity and ensure that blood flows back up to the heart. When venous valves become damaged or weakened, blood can pool in the veins, leading to conditions such as varicose veins or chronic venous insufficiency.
Transient global amnesia
Retrograde amnesia
Hippocampus
Valsalva maneuver
Anterograde amnesia
Jet lag
Amnesia
Transient epileptic amnesia
Trip Gabriel
Memory
The Forgotten Day
Duane Graveline
Papez circuit
Fabrice Bartolomei
Self-knowledge (psychology)
Dissociative amnesia
Facing Windows
Patient N.A.
Atrial septal defect
List of ICD-9 codes 390-459: diseases of the circulatory system
Raymond Delacy Adams
TGA
List of diseases (T)
Moorgate tube crash
List of MeSH codes (C23)
Ronn Owens
List of MeSH codes (F01)
List of MeSH codes (C10)
Oxazepam
List of MeSH codes (F03)
Transient global amnesia - Wikipedia
Transient Global Amnesia: Background, Pathophysiology, Epidemiology
My Experience with Transient Global Amnesia (TGA) | Psychology Today
Transient Global Amnesia Clinical Presentation: History, Physical, Causes
Evaluation of Patients with Transient Global Amnesia | AAFP
Understanding Transient Global Amnesia (TGA): An In-Depth Exploration
This New Years' Day, I Learned About Transient Global Amnesia in a Very Personal Way : ScienceAlert
Transient Global Amnesia - Neurologic Disorders - MSD Manual Professional Edition
Mimics and Severe Comorbidity in Clinically Suspected Transient Global Amnesia | PracticeUpdate
Transient global amnesia (TGA)
Transient global amnesia (TGA)
EEG in Dementia and Encephalopathy: Overview, Dementia, Vascular Dementia
Transient global amnesia associated with bilateral restricted diffusion in the lateral hippocampus - Nuffield Department of...
global transient amnesia<...
Transient Global Amnesia - Brain, Spinal Cord, and Nerve Disorders - MSD Manual Consumer Version
Cerebellar Hypoperfusion during Transient Global Amnesia: An MRI and Oculographic Study. | Read by QxMD
Long-Term Risk of Stroke After Transient Global Amnesia in Two Prospective Cohorts. - Oxford Neuroscience
Time trends, frequency, characteristics and prognosis of short-duration transient global amnesia - Radcliffe Department of...
Amnesia on Statins - RxISK
Thieme E-Journals - Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery / Full Text
Migraine in Children: Practice Essentials, Overview, Phases of a Migraine Attack
Papilledema: Causes, Symptoms, and Treatments
Montgomery, Roy: End | Midheaven Mailorder
Memory loss: MedlinePlus Medical Encyclopedia
Author Rowan Hisayo Buchanan on Writing for the Love of Words - The Aspen Institute
The ethics of molecular memory modification | Journal of Medical Ethics
IJMS | Free Full-Text | Human Brain Organoids in Migraine Research: Pathogenesis and Drug Development
These highlights do not include all the information needed to use TADALAFIL TABLETS safely and effectively. See full...
These highlights do not include all the information needed to use TADALAFIL TABLETS safely and effectively. See full...
Retrograde amnesia12
- with an inability to remember events or people from the past few minutes, hours or days (retrograde amnesia) and has working memory of only the past few minutes or less, thus they cannot retain new information or form new memories beyond that period of time (anterograde amnesia). (wikipedia.org)
- This characteristic of TGA, where the length of time affected by retrograde amnesia shortens (i.e. older memories return first, followed by more recent memories) is commonly seen. (wikipedia.org)
- In a fugue state, people not only suffer from retrograde amnesia (an inability to recall the past), but they also have erased all biographical information from their memory. (psychologytoday.com)
- Retrograde amnesia occurs when one cannot recall events from one's own past. (psychologytoday.com)
- Sometimes, retrograde amnesia occurs following a blow to the head that results in the loss of events that occurred just prior to the injury, but the memory loss can be much more extensive and debilitating if there has been severe brain damage. (psychologytoday.com)
- There are many well-known cases of individuals who have experienced these types of amnesia, with one of the most famous being that of Clive Wearing , a gifted British musician who developed both profound anterograde and retrograde amnesia, resulting in a desperate existence. (psychologytoday.com)
- Transient global amnesia is characterized by sudden-onset anterograde and retrograde amnesia that typically lasts up to 24 hours. (msdmanuals.com)
- But a less severe retrograde amnesia may be the presenting symptom. (msdmanuals.com)
- Is it possible that Christie suffered from what is called retrograde amnesia as a result of an automobile accident and was no longer capable of remembering the event? (scientificamerican.com)
- Although affected persons may be as attentive and awake as ever, their access to previously acquired memories may be disturbed (retrograde amnesia). (scientificamerican.com)
- Rarely, do anterograde and retrograde amnesia impact the person at the same time. (howtohacklifeaffairs.com)
- During a TGA episode, a person cannot form new memories (a condition called anterograde amnesia) and has difficulty recalling recent memories (a condition called retrograde amnesia). (web.app)
Diagnosis of transient2
- If any lateralizing or focal findings are noted on the examination, then the diagnosis of transient global amnesia should be questioned. (medscape.com)
- Following a negative MRI the following day, the diagnosis of transient global amnesia was made. (newmediaexplorer.org)
Benign3
- The authors conclude that transient global amnesia is a benign syndrome with a low risk of subsequent neurologic or vascular disease. (aafp.org)
- We understand that Jim had an episode of transient global amnesia , a benign condition as mysterious as it is uncommon. (sciencealert.com)
- Background and Purpose- Transient global amnesia (TGA) is known as a benign syndrome, but recent data from neuroradiological studies support an ischemic cause in some cases, which might suggest an increased susceptibility to cerebrovascular events. (ox.ac.uk)
Neurological4
- Transient global amnesia (TGA) is a neurological disorder whose key defining characteristic is a temporary but almost total disruption of short-term memory with a range of problems accessing older memories. (wikipedia.org)
- This is the conundrum of transient global amnesia (TGA) , a neurological phenomenon that remains largely enigmatic. (localquoter.net)
- Although there have been hundreds of reported cases of transient global amnesia in the medical literature, the cause is still unknown, and it is regarded as one of the most mysterious of all the neurological conditions," says Baird. (sciencealert.com)
- We obtained a total of 3.89% complications: 2.33% reflection vasovagal, 0.56% allergic skin reaction, anaphylactic shock 0.07%, 0.27% femoral hematoma, 0.26% transient neurological deficit, 0.12% permanent neurological deficit and no case of death. (thieme-connect.de)
20202
- The etiology of this form of amnesia 8 Dec 2020 Introduction. (web.app)
- Podcasts & Event Recordings Colonial Amnesia and Racial Justice in Europe 14 maj 2020 - Idlib, the last redoubt of Syrian rebels fighting President Bashar al-Assad's regime, presents an international political conundrum that threatens When Langdon wakes up in an Italian hospital with amnesia, he teams up with the unleashing a global virus that would wipe out half of the world's population. (web.app)
Syndrome5
- The differences are sufficiently meaningful that transient amnesia may be considered a heterogeneous clinical syndrome with multiple etiologies, corresponding mechanisms, and differing prognoses. (wikipedia.org)
- As the syndrome resolves, the amnesia improves, but the patient may be left with a distinct lapse of recollection for events during the attack. (medscape.com)
- Transient global amnesia (TGA) is a well-described syndrome, but one whose exact etiology is not yet completely understood. (medscape.com)
- Transient semantic amnesia: a new syndrome? (bmj.com)
- Transient global amnesia (TGA) is a mysterious syndrome causing a relatively brief inability to form new memories. (web.app)
Case of amnesia2
- In her novel The Lost Days of Agatha Christie, American therapist Carole Owens doubts this was a case of amnesia because the author clearly remembered the name of her husband's lover, at least to the extent that she used it in Harrogate. (scientificamerican.com)
- For every case of amnesia, thousands of cases of extreme forgetfullness, incapacitating confusion and profound disorientation have been and are being reported. (newmediaexplorer.org)
Type of amnesia2
- This type of amnesia may be caused by severe emotional stress, but in such cases, people almost always retain knowledge of who they are and of those with whom they are close. (scientificamerican.com)
- The person could have more than one type of amnesia condition, and it could be long-lasting and temporary. (howtohacklifeaffairs.com)
Etiology1
- The etiology of transient global amnesia is not clear. (msdmanuals.com)
Ischemic2
- Although confusion is sometimes reported, others consider this an imprecise observation, but an elevated emotional state (compared to patients experiencing Transient Ischemic Attack, or TIA) is common. (wikipedia.org)
- Medical recertification is possible for pilots who have had a stroke, transient ischemic attack, transient global amnesia, or other disturbance of consciousness. (aopa.org)
Recurrent2
- There is no increased incidence of vascular deaths or epilepsy in patients with an episode of transient global amnesia, but a significantly greater proportion of persons with recurrent episodes of transient global amnesia go on to experience epilepsy than do control subjects. (aafp.org)
- Stroke morbidity is not increased in patients with transient global amnesia, and the risk of a recurrent attack of transient global amnesia within five years ranges from 3 to 20 percent. (aafp.org)
Memories6
- Anterograde amnesia is the inability to form new memories, and it may result from damage to the hippocampus that has occurred through accident or disease. (psychologytoday.com)
- People with Transient global amnesia (TGA) does not lose consciousness , but does lose the ability to form new lasting memories. (psychology-lexicon.com)
- People with transient global amnesia suddenly but temporarily become unable to store new memories or to recall events that occurred during the episode. (msdmanuals.com)
- People with transient global amnesia suddenly but temporarily lose the ability to recall events that happened after or before the amnesia occurred and to store new memories. (msdmanuals.com)
- Temporary amnesia caused by alcohol or a drug, like transient global amnesia, can impair concentration, the ability to think clearly, and the ability to form and store new memories. (msdmanuals.com)
- The main sign of amnesia is losing memory and the incapability of the person to develop new memories. (howtohacklifeaffairs.com)
Episodic4
- Episodic memory in transient global amnesia: encoding, storage, or retrieval deficit? (bmj.com)
- This argument, however, is less than cogent because we know today that partial amnesia can occur and that it can affect certain memory systems such as episodic memory (of events) while leaving semantic (factual) memory intact. (scientificamerican.com)
- Transient global amnesia (TGA) is an episodic memory disorder that affects the hippocampus (Eustache et al. (web.app)
- The purpose of this study is to establish a diagnosis in transient global amnesia (TGA) in assessing three episodic memory's abilities (mental simulation throught Kliniska prövningar på Transient Global Amnesia. (web.app)
Symptom1
- Fortunately there is no suggestion that Jim's temporary brush with amnesia is a symptom of ill health. (sciencealert.com)
Brain6
- Amnesia resulting from physical problems with the brain are more common. (psychologytoday.com)
- Amnesia is when you lose a large chunk of memory in the long term because of psychological trauma, brain injury, or illness. (howtohacklifeaffairs.com)
- Global hypoxia-ischemia interrupts oxygen delivery and blood flow to the entire brain. (cdc.gov)
- Previous studies of global brain hypoxia ischemia have primarily focused on injury to the cerebral cortex and to the hippocampus. (cdc.gov)
- We therefore investigated the impact of global brain hypoxia-ischemia on the thalamic circuit function in the somatosensory system of young rats. (cdc.gov)
- Global brain hypoxia-ischemia during cardiac arrest has a long-term impact on processing and transfer of sensory information by thalamic circuitry. (cdc.gov)
Symptoms2
- Doctors diagnose this amnesia based mainly on symptoms and certain magnetic resonance imaging findings. (msdmanuals.com)
- Doctors usually diagnose transient global amnesia based mainly on symptoms. (msdmanuals.com)
Episodes2
Temporary3
- Transient global amnesia is a sudden, temporary loss of memory for events before, during, and after the event that caused the amnesia. (msdmanuals.com)
- What causes transient global amnesia is not known, but a similar, temporary loss of memory can result from drinking too much alcohol or taking certain drugs. (msdmanuals.com)
- It is temporary amnesia, but the duration relies on the severity of the injury. (howtohacklifeaffairs.com)
Cognitive2
- There was an absence of clouding of consciousness or other cognitive impairment other than amnesia. (wikipedia.org)
- This cerebral complication of malaria is implicated particularly with lasting cognitive deficits that owing to the high prevalence of disease worldwide may contribute significantly to the global burden of psychiatric morbidity [ 1 ]. (biomedcentral.com)
Dissociative1
- The type that perhaps comes to mind most quickly is the amnesia that accompanies a dissociative fugue state . (psychologytoday.com)
Severe1
- These tests can help rule out other possible causes of the amnesia (eg, severe anemia, clotting disorders). (msdmanuals.com)
Unclear1
- The exact mechanism that produces transient global amnesia is unclear. (medscape.com)
Sudden-onset1
- Transient global amnesia (TGA) is a condition characterized by sudden onset of memory loss and confusion. (web.app)
Occur1
- In addition, short-term memory lapses such as transient global amnesia lasting no more than 24 hours are known to occur. (scientificamerican.com)
Clinical2
- The diagnostic criteria for TGA, as defined for purposes of clinical research, include: The attack was witnessed by a capable observer and reported as being a definite loss of recent memory (anterograde amnesia). (wikipedia.org)
- Detailed work-ups are unproductive in patients who have all of the features of transient global amnesia unless other clinical indications are present. (aafp.org)
Impairment1
- And the amnesia is just the tip of the iceberg of the true incidence of memory impairment associated with Lipitor, Mevacor and Zocor. (newmediaexplorer.org)
Stroke1
- Long-Term Risk of Stroke After Transient Global Amnesia in Two Prospective Cohorts. (ox.ac.uk)
Confusional1
- These include acute confusional states such as toxin-induced memory loss, psychogenic amnesia and transient complex partial seizures that present in the postictal state. (aafp.org)
Disorders1
- However, several disorders may be misdiagnosed as transient global amnesia. (aafp.org)
Inability1
- Transient global amnesia involves the sudden loss of memory of recent events and a transient inability to retain new information. (aafp.org)
Incidence1
- The annual incidence of transient global amnesia is between 3.4 and 10.4/100 000. (msdmanuals.com)
Hours1
- Six weeks later I descended again into the black pit of amnesia, this time for an extraordinary 12 hours. (newmediaexplorer.org)
Diagnose1
- When diagnostic criteria are properly applied, transient global amnesia is not difficult to diagnose because it is a unique entity. (aafp.org)
Profound1
- The degree of amnesia is profound, and, in the interval during which the individual is aware of his or her condition, is often accompanied by anxiety. (wikipedia.org)
Stressful1
- Whether a cancer diagnosis, a severely stressful life event, Q: Transient Global Amnesia. (web.app)
Occurs1
- Transient global amnesia usually occurs in people aged 50 to 70. (msdmanuals.com)
Morbidity1
- Yet similarly, anti-malarial drugs, particularly of the quinine-like class of quinolines commonly used in treatment and prevention of disease, are also increasingly recognized to exert potentially chronic psychiatric adverse effects that may also contribute to this global burden of morbidity [ 2 ]. (biomedcentral.com)
Condition4
- Therein lies the 'transient' nature of this condition. (localquoter.net)
- Thus, the transient nature of TGA is an integral part of the condition. (localquoter.net)
- This condition is known as transient global amnesia, now known to be associated with statin drug use. (newmediaexplorer.org)
- Transient global amnesia (TGA) is a rare medical condition in which a person experiences a sudden episode of memory loss. (web.app)
Phenomenon1
- Transient global amnesia (TGA) has been a well-described phenomenon for more than 40 years. (medscape.com)
Disorder1
- Transient Global Amnesia (TGA) is a rare disorder of unknown cause. (medicine-opera.com)
Loss of mem1
- Clinically, it manifests with a paroxysmal, transient loss of memory function. (medscape.com)
Emotional1
- Most cases of transient global amnesia are preceded by an emotional stress, intense pain or cold, or strenuous physical activity. (aafp.org)
Episode1
- Most people with transient global amnesia have only one episode in a lifetime, unless the cause is seizures or migraines. (msdmanuals.com)
Mysterious1
- Was Agatha Christie's Mysterious Amnesia Real or Revenge on Her Cheating Spouse? (scientificamerican.com)
Alcohol1
- Usually, amnesia recurs only if they drink the same amount of alcohol or take the same amount of the drug. (msdmanuals.com)
People1
- Amnesia Ibiza The Best Global Club People From Ibiza party 2009 Djs Les Schmitz Caal Smile Performances Micah Ruben Mora Lorena Tena Zircaos. (web.app)