Antitumour activity of Angelica archangelica leaf extract. (1/4)
BACKGROUND: The purpose of this study was to examine the effect of a leaf extract from A. archangelica on the growth of Crl mouse breast cancer cells in vitro and in vivo. MATERIALS AND METHODS: The antiproliferative activity of the extract was measured by 3H-thymidine uptake in the Crl cells in vitro. Twenty mice were injected with the Crl cells, and 11 of them were fed A. archangelica leaf extract, and the progress of the tumours was followed. RESULTS: The leaf extract was mildly antiproliferative on the Crl cells with an EC50 of 87.6 microg/ml The antitumour activity of the extract was expressed in the mice by marked reduction in tumour growth. In the experimental animals, 9 out of 11 mice developed no or very small tumours, whereas control animals, not receiving the extract, developed significantly larger tumours (p<0.01), as estimated by Mann-Whitney U-test. The antitumour activity of the leaf extract could not be explained by the antiproliferative activity of furanocoumarins present in the extract. CONCLUSION: The results demonstrate the antiproliferative activity in vitro and antitumour activity in vivo of a leaf extract from A. archangelica (+info)The cytotoxic effect of two chemotypes of essential oils from the fruits of Angelica archangelica L. (2/4)
BACKGROUND: The aim of this work was to study the constituents and cytotoxicity of the essential oils from the fruits of Angelica archangelica growing in Iceland. MATERIALS AND METHODS: Three samples of essential oils were prepared by steam distillation. Their composition was established with GC/MS. The effects of the oils were examined in PANC-1 human pancreas cancer cells and Crl mouse breast cancer cells in concentrations ranging from 10-400 microg/ml, measuring the reduction of the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl) -5- (3-carboxymethoxyphenyl)-2- (4-sulphophenyl) -2H-tetrazolium (MTS) by mitochondrial enzymes. RESULTS: Two types of essential oils were found, differing mainly in the absence or presence of beta-phellandrene. The ED50 of the oils ranged from 48.6 microg/ml to 108.3 microg/ml for PANC-1 and 48.0 microg/ml to 91.8 microg/ml for Crl cells. CONCLUSION: The cytotoxic activity of the essential oils was independent of the quantity of their main components. (+info)Anti-anxiety activity of successive extracts of Angelica archangelica Linn. on the elevated T-maze and forced swimming tests in rats. (3/4)
OBJECTIVE: Angelica archangelica Linn. is widely used in food and liquor preparations and also in Kashmiri folk medicine to reduce anxiety. We evaluated the anxiolytic effect of successive extracts of A. archangelica linn. (SAE) on rats tested in the elevated T-maze test (an animal model of generalized anxiety) at doses that exhibit antidepressant-like activity in humans. METHODS: A. archangelica (1 kg) was subjected to successive extraction in a soxhlet apparatus with solvents [petroleum ether (40-60 degrees C), chloroform, ethyl acetate, methanol and decoction with water] in order of increasing polarity (yield: 6.9%, 7.3%, 5.1%, 11.88% and 8.2% w/w, respectively). SAE were evaluated for anxiolytic effects using the elevated T-maze and forced swimming tests in rats. RESULTS: Oral dosing of diazepam (1 mg/kg) and extracts (50, 100 and 200 mg/kg) clearly showed an anxiolytic-like profile in the elevated T-maze test: it increased one-way escape and decreased inhibitory avoidance on the first, third and seventh day. In the forced swimming test, imipramine and SAE showed antidepressant- and anxiolytic-like effects as reflected by increased climbing time, swimming time and decreased immobility time on the first, third and seventh day. Aqueous and methanol extracts showed the most, petroleum ether (40-60 degrees C) and chloroform intermediate, and ethyl acetate the least anxiolytic activity (*P<0.05, **P<0.01, ***P< 0.001) in both models. CONCLUSIONS: These results suggest the anti-anxiety activity of various extracts of A. archangelica and strongly justify its use in traditional Indian medicine for the treatment of anxiety. (+info)A parallel, randomized, double-blind, placebo-controlled study to investigate the effect of SagaPro on nocturia in men. (4/4)
(+info)'Angelica archangelica' is the botanical name for a plant species also known as Garden Angelica or Wild Celery. It belongs to the family Apiaceae and is native to temperate regions of Europe, northern Asia, and Greenland. The plant can grow up to 2 meters tall and has large, bright green, compound leaves and umbels of small white flowers.
The root, seeds, and stems of 'Angelica archangelica' have been used in traditional medicine and cooking for centuries. In herbal medicine, the root is often used to treat digestive problems such as gas, bloating, and loss of appetite, while the seeds are used to alleviate menstrual cramps and respiratory issues. The plant contains several bioactive compounds, including essential oils, coumarins, and furanocoumarins, which contribute to its medicinal properties.
However, it is important to note that 'Angelica archangelica' can interact with certain medications and may cause adverse effects in some individuals. Therefore, it is recommended to consult a healthcare professional before using this plant for medicinal purposes.
'Angelica' is a common name that refers to several plant species in the genus Angelica. The most commonly used medicinally is Angelica archangelica, also known as garden angelica or wild celery. This herb has been used in traditional medicine for various purposes, such as:
1. Digestive aid: It is believed to stimulate appetite, ease digestion, and reduce gas and bloating.
2. Respiratory health: Angelica has been used to treat respiratory conditions like bronchitis, colds, and coughs.
3. Menstrual discomfort: Some people use it to alleviate menstrual cramps and PMS symptoms.
4. Nervous system: It may help reduce anxiety and promote relaxation.
5. Skin issues: The herb has been used topically for skin irritations, wounds, and insect bites.
However, it is essential to note that while angelica has potential health benefits, it can also have side effects and interact with certain medications. Pregnant women should avoid using this herb, as it may stimulate uterine contractions and lead to miscarriage. Always consult a healthcare professional before starting any new supplement or medication.
'Angelica sinensis', also known as Dong Quai or Chinese Angelica, is a herbaceous plant native to China. It has been used in traditional Chinese medicine for centuries for various purposes, such as promoting menstruation and blood circulation, alleviating menopausal symptoms, and treating anemia, among others.
The roots of the plant are typically harvested and dried before being used in various forms, including powders, capsules, and teas. Some studies suggest that 'Angelica sinensis' may have medicinal properties due to its high content of essential oils, phytochemicals, and other bioactive compounds. However, more research is needed to fully understand its potential health benefits and risks.
It is important to note that while some natural remedies can be beneficial, they should not be used as a substitute for professional medical advice or treatment. It is always recommended to consult with a healthcare provider before starting any new supplement regimen.
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Officinalis3
- Synonyms include Archangelica officinalis Hoffm. (wikipedia.org)
- and Angelica officinalis Moench. (wikipedia.org)
- Angelica officinalis subsp. (wikimedia.org)
Apiaceae2
- Angelica archangelica, commonly known as angelica, garden angelica, wild celery, and Norwegian angelica, is a biennial plant from the family Apiaceae, a subspecies of which is cultivated for its sweetly scented edible stems and roots. (wikipedia.org)
- Angelica plants are in the Apiaceae family (formerly the Umbelliferae family) which makes it related to Dill , Chervil, Caraway, Queen's Anne Lace and Lovage . (mountainvalleygrowers.com)
Garden angelica1
- Angelica Leaf (Angelica archangelica ) is sometimes known as Wild Parsnip, Holy Ghost Root, Garden Angelica, Wild Celery, and Norwegian Angelica is used extensively in herbal medicine. (luminescents.net)
Sinensis2
- We now know that the Chinese have been using Angelica sinensis or Dong Quai for centuries. (mountainvalleygrowers.com)
- It is a cousin to the Chinese herb known as Dong Quai ( Angelica sinensis ). (emsherbals.com)
Seeds6
- Angelica Archangelica Seeds Mainly cultivated in France in the "Marais Poitevin", a marsh region close to Niort in the department of Deux-Sevres, known for the excellence of its dairy products, especially butter. (lepicerie.com)
- Angelica seeds and angelica roots are used in liqueur making, such as Chartreuse, Benedictine, Vermouth and Dubonnet, but also sometimes in absinthe. (lepicerie.com)
- Other uses: Burn angelica seeds to perfume a room! (lepicerie.com)
- After only a few weeks, the germination rate for Angelica seeds declines dramatically. (mountainvalleygrowers.com)
- Angelica archangelica (Angelica): Seeds and Plants available to buy. (jekkas.com)
- For example, Ojala 15 observed that seed mass and germination percentage of Angelica archangelica were higher in seeds on the primary umbel than in those on secondary, tertiary, and quaternary umbels. (nature.com)
Subsp2
- The water root extract of A. archangelica subsp. (wikipedia.org)
- Angelica archangelica subsp. (wikimedia.org)
Tincture1
- Angelica Tincture. (octoberfields.com)
Litoralis1
- Angelica litoralis (Wahlenb. (wikimedia.org)
Plants2
- Angelica archangelica L." Plants of the World Online. (wikipedia.org)
- Some angelica plants flower white blossoms or more rarely, pale-purple flowers. (herb-basics.com)
Herbs1
- Like most biennials in the world of herbs, Angelica is a fairly flat mass of a few large leaves the first year. (mountainvalleygrowers.com)
Atropurpurea3
- Masterwort (A. atropurpurea) also called angelica. (herb-basics.com)
- Below are the main rubriks (i.e strongest indications or symptoms) of Angelica Atropurpurea in traditional homeopathic usage , not approved by the FDA. (abchomeopathy.com)
- Angelica Atropurpurea is not available to buy over the counter. (abchomeopathy.com)
Biennial1
- Angelica is a biennial producing foliage the first year and stems and flowers the second. (herb-basics.com)
Medicinal2
- From the 10th century on, angelica was cultivated as a vegetable and medicinal plant, and achieved popularity in Scandinavia in the 12th century and is used especially in Sámi culture. (wikipedia.org)
- What are the Medicinal Properties of Wild Celery ( Angelica Archangelica)? (wikipedia.org)
Herbal2
- In a Modern Herbal , Maude Grieve gives us a recipe for concocting your own Angelica liqueur, delicious and good for the digestive system. (mountainvalleygrowers.com)
- Click here to be notified by email when Angelica herbal extract becomes available. (octoberfields.com)
Extract5
- Background: The purpose of this study was to examine the effect of a leaf extract from A. archangelica on the growth of Crl mouse breast cancer cells in vitro and in vivo. (iiarjournals.org)
- Twenty mice were injected with the Crl cells, and 11 of them were fed A. archangelica leaf extract, and the progress of the tumours was followed. (iiarjournals.org)
- Angelica archangelica 1 :1 extract hat noch keine Rezensionen. (avalonmagicplants.com)
- Start with Angelica extract and add anything else you want to it. (herbies-herbs.com)
- Angelica Root Extract 1 oz. 50% pure grain alcohol base. (lifebalm.com)
Roots2
- Angelica archangelica roots are among the most common botanicals used in gin distillation, often used in concert with juniper berries and coriander as a chief aromatic characteristic for gin. (wikipedia.org)
- The essential oil content of angelica root varies based on the age of the roots. (wikipedia.org)
Umbelliferae1
- Angelica is unique among the Umbelliferae for its pervading aromatic odor, a pleasant perfume entirely different from fennel, parsley, anise, caraway, or chervil. (wikipedia.org)
Stems1
- The hollow stems of Angelica archangelica may be eaten. (wikipedia.org)
Herb4
- One of the most unusual uses for any herb has to be candied Angelica stalks. (mountainvalleygrowers.com)
- Angelica makes an interesting addition to our Gourmet Herb Garden Six Pack and a tasty addition to our Edible Flower Herb Garden Six Pack . (mountainvalleygrowers.com)
- Magical Properties: A potent protective herb, Angelica offers a barrier against negative energy while simultaneously attracting positive energy. (tragicbeautiful.com)
- this relative of Angelica is a widely used herb in traditional Chinese medicine. (tradewindsfruit.com)
Grows1
- Angelica grows only in damp soil, preferably near rivers or deposits of water. (wikipedia.org)
Gigas1
- A. gigas (Korean angelica) is an exquisite ornamental introduced to the United States in the early 1980's. (herb-basics.com)
Grieve1
- In the 1930's, Maude Grieve also wrote that A. archangelica is the only species employed medicinally. (mountainvalleygrowers.com)
Freshly2
- An ounce of freshly gathered stem of Angelica is chopped up and steeped in 2 pints of Good Brandy (none of that cheep stuff) with 1 ounce of bitter almonds reduced to a pulp for five days. (mountainvalleygrowers.com)
- The flavor of Angelica is similar to licorice, used in teas either freshly harvested or dried. (marysheirloomseeds.com)
Liqueur1
- Chopped Angelica root was added to the notorious addictive liqueur Absinthe (banned in this country from 1913 to 2007), probably to tame the taste of the acrid Wormwood . (mountainvalleygrowers.com)
Intestinal gas1
- Excessive intestinal gas, heartburn is relieved with Angelica. (shophomeo.com)
Celery1
- Like Lovage, there is a slight celery flavor in the leaves of Angelica and they can be used as a substitute for this in recipes. (mountainvalleygrowers.com)
Stalk1
- The second year the Angelica plant rises to a towering four feet as it puts forth its flowering stalk. (mountainvalleygrowers.com)
Grown1
- Angelica has been grown as a food and medicine for over a thousand years. (emsherbals.com)
Species1
- There are about 30 species of Angelica. (mountainvalleygrowers.com)
Leaf1
- An infusion of Angelica leaf, used as a wash for the face, is said to prevent acne. (luminescents.net)
Regular1
- Regular users of Angelica root develop a distaste for alcoholic beverages. (herb-basics.com)
Stimulate1
- Angelica is useful to stimulate the circulation. (shophomeo.com)
Cramps1
- Angelica is useful in abdominal cramps, indicated for nausea, in colics. (shophomeo.com)
Flavor2
- Angelica has also been used to flavor Vermouth and Chartreuse. (mountainvalleygrowers.com)
- Angelica has a way of enhancing the flavor of some fruits, rhubarb in particular has been paired with young Angelica leaves to reduce the acidity of the rhubarb. (mountainvalleygrowers.com)
Nervous1
- Indian and Chinese medicine employ A. archangelica to treat nervous conditions including migraine, anorexia, and anxiety . (emsherbals.com)
Soil3
- Angelica can grow 5 to 8 feet tall, needs rich, moist, well-drained soil in partial shade. (herb-basics.com)
- GROWING: Angelica needs rich, moist garden soil in partial shade. (herb-basics.com)
- Angelica is a flowering perennial plant, found growing wild in damp soil in northern and central parts of Eurasia, and cultivated mainly in France and eastern Europe. (emsherbals.com)