Ischemia or infarction of the spinal cord in the distribution of the anterior spinal artery, which supplies the ventral two-thirds of the spinal cord. This condition is usually associated with ATHEROSCLEROSIS of the aorta and may result from dissection of an AORTIC ANEURYSM or rarely dissection of the anterior spinal artery. Clinical features include weakness and loss of pain and temperature sensation below the level of injury, with relative sparing of position and vibratory sensation. (From Adams et al., Principles of Neurology, 6th ed, pp1249-50)
Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.
DUODENAL OBSTRUCTION by the superior mesenteric artery (MESENTERIC ARTERY, SUPERIOR) which travels in the root of the MESENTERY and crosses over the DUODENUM. The syndrome is characterized by the dilated proximal duodenum and STOMACH, bloating, ABDOMINAL CRAMPS, and VOMITING. Often it is observed in patient with body casts after spinal surgery.
Pathological processes involving any of the BLOOD VESSELS feeding the SPINAL CORD, such as the anterior and paired posterior spinal arteries or their many branches. Disease processes may include ATHEROSCLEROSIS; EMBOLISM; and ARTERIOVENOUS MALFORMATIONS leading to ISCHEMIA or HEMORRHAGE into the spinal cord (hematomyelia).
Surgical formation of an opening into the DUODENUM.
The first branch of the SUBCLAVIAN ARTERY with distribution to muscles of the NECK; VERTEBRAE; SPINAL CORD; CEREBELLUM; and interior of the CEREBRUM.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Absent or reduced sensitivity to cutaneous stimulation.
The vessels carrying blood away from the heart.
Radiography of blood vessels after injection of a contrast medium.
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.
Surgical formation of an opening through the ABDOMINAL WALL into the JEJUNUM, usually for enteral hyperalimentation.
A characteristic symptom complex.
Creation of an artificial external opening or fistula in the intestines.

The crossing of the spinothalamic tract. (1/5)

The question whether the spinothalamic and spinoreticular fibres cross the cord transversely or diagonally was investigated in cases of anterolateral cordotomy and in a case of thrombosis of the anterior spinal artery. The pattern of sensory loss following transection of the anterolateral quadrant of the cord consists of a narrow area of decreased nociception and thermanalgesia at the level of the incision; it extends for 1-2 segments cranial and cordal to the incision. This area is immediately cranial to the area of total loss of these modalities. This pattern of sensory loss is explained as follows. The cordotomy incision transects two groups of fibres: those that are already within the anterior and anterolateral funiculi and those that are crossing the cord. The area of total thermanaesthesia and analgesia is due to transection of fibres that are already within this region. The area of partial sensory loss is due to transection of the fibres that are crossing the cord at that level. Owing to the craniocaudal extent of the branches of the dorsal roots, there is an overlap of their collaterals that results in every spinothalamic neurone receiving an input from several dorsal roots. The narrow cordotomy incision thus divides the few fibres crossing at that level, causing diminished noxious and thermal sensibility over a few segments above and below the incision. These facts can be accounted for only on the assumption that these spinothalamic fibres are crossing the cord transversely. This evidence of transverse crossing was found in the cervical, thoracic and lumbar segments. There were three of 63 cordotomies for which this explanation of the partial sensory loss could not be maintained. Although no explanation has been suggested, this is unlikely to be due to the fibres crossing the cord diagonally.  (+info)

Anterior spinal artery syndrome in a girl with Down syndrome: case report and literature review. (2/5)

BACKGROUND/OBJECTIVE: Anterior spinal artery syndrome is an extremely rare cause of acute ischemic cord infarction in children. It is caused by hypoperfusion of the anterior spinal artery, leading to ischemia in the anterior two thirds of the spinal cord. The presentation is usually with an acute and painful myelopathy with impaired bladder and bowel control. Pain and temperature sensation below the lesion are lost, whereas vibration and position sense is intact because of the preservation of the posterior columns. METHODS: Case report. RESULTS: A 16-year-old girl with Down syndrome presented with urinary retention and acute complete flaccid paralysis of the legs with absent deep tendon and abdominal reflexes. Magnetic resonance imaging showed a signal abnormality in the anterior half of the thoracic cord from T5 to T12, consistent with anterior spinal artery infarction. CONCLUSIONS: Pediatricians should consider anterior spinal artery syndrome in the child who presents with acute, painful myelopathy. We summarize the etiology, neurological findings and outcomes of 19 children found in the literature with anterior spinal artery syndrome.  (+info)

Association of vascular risk factors with cervical artery dissection and ischemic stroke in young adults. (3/5)

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Arnold-Chiari malformation type 1 complicated by sudden onset anterior spinal artery thrombosis, tetraparesis and respiratory arrest. (4/5)

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Anterior spinal cord syndrome in a patient with Behcet's disease. (5/5)

Although neurological involvement in Behcet's disease is not so uncommon, isolated spinal cord disease is quite rare and reported to be observed in about 2% of all cases with neurological involvement. Here we report a Behcet's patient with spinal cord disease presented with anterior spinal cord syndrome. This rare syndrome is caused by hypoperfusion of the anterior spinal artery and to our knowledge has not been previously reported in patients with Behcet's disease. This report defines the characteristic clinical features of this entity and emphasizes the importance of early immunosuppressive treatment and initiation of rehabilitation.  (+info)

Anterior Spinal Artery Syndrome (ASAS) is a medical condition that affects the blood supply to the anterior portion of the spinal cord. This results in a lack of oxygen and nutrients being delivered to the affected area, causing damage to the nerves and tissues.

The anterior spinal artery is responsible for supplying blood to the front two-thirds of the spinal cord, which includes the corticospinal tracts (responsible for motor function) and the spinothalamic tracts (responsible for pain, temperature, and touch sensation).

ASAS can be caused by various conditions that affect the blood flow in the anterior spinal artery, such as atherosclerosis, embolism, vasculitis, or trauma. The symptoms of ASAS depend on the severity and location of the injury but may include:

* Paralysis or weakness in the legs (paraplegia) or all four limbs (tetraplegia)
* Loss of pain and temperature sensation below the level of the injury
* Absent or reduced reflexes
* Autonomic dysfunction, such as bladder and bowel incontinence or sexual dysfunction
* Muscle spasticity or rigidity

The diagnosis of ASAS is typically made based on clinical examination, imaging studies (such as MRI or CT angiography), and sometimes cerebrospinal fluid analysis. Treatment for ASAS focuses on addressing the underlying cause, managing symptoms, and promoting rehabilitation and recovery.

Infarction is the term used in medicine to describe the death of tissue (also known as an "area of necrosis") due to the lack of blood supply. This can occur when a blood vessel that supplies oxygen and nutrients to a particular area of the body becomes blocked or obstructed, leading to the deprivation of oxygen and nutrients necessary for the survival of cells in that region.

The blockage in the blood vessel is usually caused by a clot (thrombus) or an embolus, which is a small particle that travels through the bloodstream and lodges in a smaller vessel. The severity and extent of infarction depend on several factors, including the size and location of the affected blood vessel, the duration of the obstruction, and the presence of collateral circulation (alternative blood vessels that can compensate for the blocked one).

Common examples of infarctions include myocardial infarction (heart attack), cerebral infarction (stroke), and pulmonary infarction (lung tissue death due to obstruction in the lung's blood vessels). Infarctions can lead to various symptoms, depending on the affected organ or tissue, and may require medical intervention to manage complications and prevent further damage.

Superior Mesenteric Artery (SMA) Syndrome, also known as Wilkie's syndrome, is a rare vascular compression disorder. It occurs when the superior mesenteric artery and the abdominal aorta compress the third part of the duodenum, resulting in partial or complete duodenal obstruction. This compression is often caused by a loss of the normal fat pad that separates these vessels and the duodenum, which can be due to significant weight loss, surgery, or other conditions. Symptoms may include abdominal pain, nausea, vomiting, early satiety, and weight loss. The diagnosis is typically made with imaging studies such as an upper GI series or CT scan. Treatment options range from dietary modifications and medical management to surgical intervention.

Spinal cord vascular diseases refer to a group of disorders that affect the blood vessels of the spinal cord. These conditions can result in insufficient blood supply to the spinal cord tissue, leading to ischemia (lack of oxygen) and infarction (tissue death). There are several types of spinal cord vascular diseases, including:

1. Spinal Cord Infarction: This is a rare condition that occurs due to the blockage or narrowing of the arteries supplying blood to the spinal cord. It can result in sudden onset of weakness, numbness, or paralysis in parts of the body served by the affected spinal cord region.
2. Spinal Cord Aneurysm: This is a localized dilation or bulging of a weakened area in the wall of a blood vessel that supplies the spinal cord. If an aneurysm ruptures, it can cause bleeding into the spinal cord tissue, leading to neurological deficits.
3. Spinal Cord Arteriovenous Malformations (AVMs): These are abnormal connections between the arteries and veins in the spinal cord. AVMs can lead to bleeding, ischemia, or both, resulting in various neurological symptoms.
4. Spinal Cord Dural Arteriovenous Fistulas (dAVFs): These are abnormal communications between the spinal artery and a vein located outside the dura mater (the protective covering of the spinal cord). dAVFs can cause venous congestion, leading to ischemia and neurological dysfunction.
5. Spinal Cord Vasculitis: This is an inflammation of the blood vessels in the spinal cord, which can lead to narrowing or blockage of the affected vessels. It can result in various neurological symptoms, such as weakness, numbness, or pain.

Treatment for spinal cord vascular diseases depends on the specific condition and its severity. Treatment options may include medications, surgery, endovascular procedures, or a combination of these approaches.

Duodenostomy is a surgical procedure that creates an opening (stoma) into the duodenum, which is the first part of the small intestine. This procedure is typically performed to divert the flow of digestive secretions and contents away from a diseased or obstructed area of the gastrointestinal tract.

A duodenostomy may be created as a temporary measure to allow a portion of the intestine to heal or as a permanent solution for conditions such as chronic inflammatory bowel disease, cancer, or congenital abnormalities. The stoma can be located on the abdominal wall, allowing for the external drainage of digestive secretions and contents into a collection bag.

It is important to note that the specific medical definition and indications for duodenostomy may vary based on individual clinical context and patient needs. Therefore, it is always best to consult with a healthcare professional or medical expert for accurate information.

The vertebral artery is a major blood vessel that supplies oxygenated blood to the brain and upper spinal cord. It arises from the subclavian artery, then ascends through the transverse processes of several cervical vertebrae before entering the skull through the foramen magnum. Inside the skull, it joins with the opposite vertebral artery to form the basilar artery, which supplies blood to the brainstem and cerebellum. The vertebral artery also gives off several important branches that supply blood to various regions of the brainstem and upper spinal cord.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

Hyperesthesia is a medical term that refers to an increased sensitivity to sensory stimuli, including touch, pain, or temperature. It can affect various parts of the body and can be caused by different conditions, such as nerve damage, multiple sclerosis, or complex regional pain syndrome. Hyperesthesia can manifest as a heightened awareness of sensations, which can be painful or uncomfortable, and may interfere with daily activities. It is essential to consult a healthcare professional for an accurate diagnosis and appropriate treatment if experiencing symptoms of hyperesthesia.

Arteries are blood vessels that carry oxygenated blood away from the heart to the rest of the body. They have thick, muscular walls that can withstand the high pressure of blood being pumped out of the heart. Arteries branch off into smaller vessels called arterioles, which further divide into a vast network of tiny capillaries where the exchange of oxygen, nutrients, and waste occurs between the blood and the body's cells. After passing through the capillary network, deoxygenated blood collects in venules, then merges into veins, which return the blood back to the heart.

Angiography is a medical procedure in which an x-ray image is taken to visualize the internal structure of blood vessels, arteries, or veins. This is done by injecting a radiopaque contrast agent (dye) into the blood vessel using a thin, flexible catheter. The dye makes the blood vessels visible on an x-ray image, allowing doctors to diagnose and treat various medical conditions such as blockages, narrowing, or malformations of the blood vessels.

There are several types of angiography, including:

* Cardiac angiography (also called coronary angiography) - used to examine the blood vessels of the heart
* Cerebral angiography - used to examine the blood vessels of the brain
* Peripheral angiography - used to examine the blood vessels in the limbs or other parts of the body.

Angiography is typically performed by a radiologist, cardiologist, or vascular surgeon in a hospital setting. It can help diagnose conditions such as coronary artery disease, aneurysms, and peripheral arterial disease, among others.

Paraplegia is a medical condition characterized by partial or complete loss of motor function and sensation in the lower extremities, typically affecting both legs. This results from damage to the spinal cord, often due to trauma such as accidents, falls, or gunshot wounds, or from diseases like spina bifida, polio, or tumors. The specific area and extent of the injury on the spinal cord determine the severity and location of paralysis. Individuals with paraplegia may require assistive devices for mobility, such as wheelchairs, and may face various health challenges, including pressure sores, urinary tract infections, and chronic pain.

Duodenal obstruction is a medical condition characterized by the blockage or impediment of the normal flow of contents through the duodenum, which is the first part of the small intestine. This blockage can be partial or complete and can be caused by various factors such as:

1. Congenital abnormalities: Duodenal atresia or stenosis, where there is a congenital absence or narrowing of a portion of the duodenum.
2. Inflammatory conditions: Duodenitis, Crohn's disease, or tumors that cause swelling and inflammation in the duodenum.
3. Mechanical obstructions: Gallstones, tumors, strictures, or adhesions (scar tissue) from previous surgeries can physically block the duodenum.
4. Neuromuscular disorders: Conditions like progressive systemic sclerosis or amyloidosis that affect the neuromuscular function of the intestines can lead to duodenal obstruction.

Symptoms of duodenal obstruction may include nausea, vomiting (often with bilious or fecal matter), abdominal pain, distention, and decreased bowel movements. Diagnosis typically involves imaging studies such as X-rays, CT scans, or upper gastrointestinal series to visualize the blockage. Treatment depends on the underlying cause but may involve surgery, endoscopic procedures, or medications to manage symptoms and address the obstruction.

A jejunostomy is a surgical procedure where an opening (stoma) is created in the lower part of the small intestine, called the jejunum. This stoma allows for the passage of nutrients and digestive enzymes from the small intestine into a tube or external pouch, bypassing the mouth, esophagus, stomach, and upper small intestine (duodenum).

Jejunostomy is typically performed to provide enteral nutrition support in patients who are unable to consume food or liquids by mouth due to various medical conditions such as dysphagia, gastroparesis, bowel obstruction, or after certain surgical procedures. The jejunostomy tube can be used for short-term or long-term nutritional support, depending on the patient's needs and underlying medical condition.

A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.

For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.

It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.

An enterostomy is a surgical procedure that creates an opening from the intestine to the abdominal wall, which allows for the elimination of waste from the body. This opening is called a stoma and can be temporary or permanent, depending on the individual's medical condition. There are several types of enterostomies, including colostomy, ileostomy, and jejunostomy, which differ based on the specific location in the intestine where the stoma is created.

The purpose of an enterostomy may vary, but it is often performed to divert the flow of waste away from a diseased or damaged section of the intestine, allowing it to heal. Common reasons for an enterostomy include inflammatory bowel disease, cancer, trauma, and birth defects.

After the surgery, patients will need to wear a pouching system over the stoma to collect waste. They will also require specialized care and education on how to manage their stoma and maintain their overall health. With proper care and support, individuals with an enterostomy can lead active and fulfilling lives.

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