Longitudinal medical surveillance showing lack of progression of argyrosis in a silver refiner. (1/14)
Silver is a recognized cause of argyrosis and argyria. This case report describes blood silver levels and longitudinal ophthalmological examination in a previously reported case of argyrosis over a 5-year period. (+info)Long-term effects of Ag-containing alloys on mucous tissue present in biopsy samples. (2/14)
The aim of this study was to investigate the long-term effects of alloys containing silver (mainly Ag-Sn alloy) on oral mucous tissue. We observed biopsy tissue specimens from patients diagnosed as having amalgam tattoo and/or metal pigmentation by light and electron microscopy and electron-probe microanalysis (EPMA). In most cases, Ag-Sn alloy was present in the tissue but it could not be confirmed if the alloy originated from amalgam. Distributions of both Ag-S and Ag-Sn have typical patterns. Most Ag forms Ag2S and is stably deposited in three patterns along the collagen, basement membrane, and fibrous cells without inducing any host reaction. On the other hand, Sn forms large granules that contain Ag, S, C, N, P, and Ca, and is in soft state in the tissue. Tissue reactions to the alloy become weaker as time passes. (+info)Immunolocalization of HLA-DR and metallothionein on amalgam tattoos. (3/14)
Despite studies concerning toxic reactions related to amalgam components in the literature, few studies have been devoted to evaluate local noxious effects of amalgam tattoos (AT) on biological tissues. In addition, little is known about activation of inflammatory cells by mucosa-implanted amalgam debris. Tissue reaction to AT depends on the particle size. Human leukocyte antigen DR (HLA-DR) is an activation marker of inflammatory cells associated with antigen presentation. Metallothioneins (MT) are proteins involved with metal detoxication, including mercury and silver. The purpose of the present study was to investigate the immunolocalization of HLA-DR and MT in AT with large or powdered particles. Paraffin-embedded AT tissue blocks were sectioned and subjected to immunohistochemistry for HLA-DR and MT localization. The results demonstrated a dense mononuclear inflammatory infiltrate associated with large and powdered debris and positivity for HLA-DR and MT in inflammatory cells. While blood vessel walls and connective fibers impregnated with powdered particles were negative for HLA-DR, they were positive for MT. In addition, wherever epithelial basement membrane impregnation by powdered amalgam particles was observed, a strong positivity for MT was detected. These findings demonstrate that residual elements of AT still have noxious local effects over tissues. (+info)Exposure-related health effects of silver and silver compounds: a review. (4/14)
A critical review of studies examining exposures to the various forms of silver was conducted to determine if some silver species are more toxic than others. The impetus behind conducting this review is that several occupational exposure limits and guidelines exist for silver, but the values for each depend on the form of silver as well as the individual agency making the recommendations. For instance, the American Conference of Governmental Industrial Hygienists has established separate threshold limit values for metallic silver (0.1 mg/m3) and soluble compounds of silver (0.01 mg/m3). On the other hand, the permissible exposure limit (PEL) recommended by the Occupational Safety and Health Administration and the Mine Safety and Health Administration and the recommended exposure limit set by the National Institute for Occupational Safety and Health is 0.01 mg/m3 for all forms of silver. The adverse effects of chronic exposure to silver are a permanent bluish-gray discoloration of the skin (argyria) or eyes (argyrosis). Most studies discuss cases of argyria and argyrosis that have resulted primarily from exposure to the soluble forms of silver. Besides argyria and argyrosis, exposure to soluble silver compounds may produce other toxic effects, including liver and kidney damage, irritation of the eyes, skin, respiratory, and intestinal tract, and changes in blood cells. Metallic silver appears to pose minimal risk to health. The current occupational exposure limits do not reflect the apparent difference in toxicities between soluble and metallic silver; thus, many researchers have recommended that separate PELs be established. (+info)Silver deposition and tissue staining associated with wound dressings containing silver. (5/14)
Argyria is the general term used to denote a clinical condition in which excessive administration and deposition of silver causes a permanent irreversible gray-blue discoloration of the skin or mucous membranes. The amount of discoloration usually depends on the route of silver delivery (ie, oral or topical administration) along with the body's ability to absorb and excrete the administered silver compound. Argyria is accepted as a rare dermatosis but once silver particles are deposited, they remain immobile and may accumulate during the aging process. Topical application of silver salts (eg, silver nitrate solution) may lead to transient skin staining. To investigate their potential to cause skin staining, two silver-containing dressings (Hydrofiber and nanocrystalline) were applied to human skin samples taken from electively amputated lower limbs. The potential for skin discoloration was assayed using atomic absorption spectroscopy. When the dressings were hydrated with water, a significantly higher amount of silver was released from the nanocrystalline dressing compared to the Hydrofiber dressing (P <0.005), which resulted in approximately 30 times more silver deposition. In contrast, when saline was used as the hydration medium, the release rates were low for both dressings and not significantly different (silver deposition was minimal). Controlling the amount of silver released from silver-containing dressings should help reduce excessive deposition of silver into wound tissue and minimize skin staining. (+info)Quantitative near infrared spectroscopic analysis of Q-Switched Nd:YAG treatment of generalized argyria. (6/14)
(+info)Argyria -- case report. (7/14)
(+info)Argyria mimicking a blue nevis: dermoscopy features. (8/14)
(+info)Argyria is a rare, cosmetic condition that results from excessive exposure to silver and its compounds, leading to the accumulation of silver particles in various tissues of the body, particularly the skin. The most noticeable symptom of argyria is the development of a blue-gray or slate-gray discoloration of the skin, mucous membranes, and eyes. This condition is usually permanent and not harmful to one's health, but it can cause significant psychological distress due to its impact on appearance.
The primary causes of argyria are long-term use or misuse of silver-containing medications, dietary supplements, or topical products that contain silver compounds like silver nitrate, silver sulfadiazine, and colloidal silver. Prolonged exposure to silver dust in occupational settings can also lead to argyria.
It is important to note that argyria should not be confused with generalized silver toxicity or acute silver poisoning, which can have more severe health consequences.
Argyria
Argyria interrupta
Argyria argyrodis
Argyria supposita
Argyria heringi
Argyria sericina
Argyria (disambiguation)
Argyria pontiella
Argyria mesogramma
Argyria xanthoguma
Argyria sordipes
Argyria polyniphas
Argyria lusella
Argyria rufisignella
Argyria multifacta
Argyria opposita
Argyria tunuistrigella
Argyra argyria
Argyria schausella
Argyria divisella
Argyria vestalis
Argyria (Troad)
Argyria venatella
Argyria vesta
Argyria croceicinctella
Argyria centrifugens
Argyria oxytoma
Argyria plumbolinealis
Argyria lucidellus
Argyria (moth)
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Discoloration of the skin4
- Argyria is the gray/blue discoloration of the skin caused by the ingestion of certain types of silver preparations. (wgpeters.com)
- The request was prompted by concerns about one employee who had been diagnosed as having argyria, a blue-grey discoloration of the skin, mucous membranes, and/or eyes resulting from prolonged silver exposure. (cdc.gov)
- argyria - A discoloration of the skin wherein the skin turns a blue-grey color as a result of over exposure to certain forms of silver. (silver-colloids.com)
- The most common is argyria, a build-up of silver in the body's tissues causing a bluish-gray discoloration of the skin, which is usually permanent. (nih.gov)
Colloidal silver8
- Chronic ingestion or inhalation of silver preparations (especially colloidal silver) can lead to argyria in the skin and other organs. (wikipedia.org)
- Argyria following the use of dietary supplements containing colloidal silver protein. (medscape.com)
- Many purveyors of colloidal silver say that ionic silver cannot cause argyria because ions are the smallest size and cannot get 'stuck' within cells. (wgpeters.com)
- Argyria There is a general concern that the use of colloidal silver may cause a condition known as argyria. (highppmsilver.com)
- Gaul LE, Staud AH: Seventy cases of generalized argyria following organic and colloidal silver medication, including biospectrometric analysis of ten cases. (rosemaryjacobs.com)
- This will tell you how many DROPS (i.e., from an eye dropper) of colloidal silver you can take each day, safely, for a lifetime, without fear of ending up with argyria (i.e., skin-staining). (blogspot.com)
- Once you end up with argyria - the blue-gray skin-staining that typifies long-term excessive usage of colloidal silver - you can't switch gears and start blaming others for it. (blogspot.com)
- As far as scientists can tell, those deposits may just be like the blue skin people get when they consume too much colloidal silver - the skin color may help doctors diagnose a person with argyria but giving the patient a spray tan isn't going to improve their health. (skepchick.org)
Cannot cause argyria1
- Your product allegedly contains silver and water yet you tell me it cannot cause argyria. (rosemaryjacobs.com)
Lead to argyria1
- Prolonged use of SSD cream may lead to argyria. (escholarship.org)
Diagnosis2
- The diagnosis of argyria is established by skin biopsy with formaldehyde-fixed paraffin-embedded sections stained with hematoxylin-eosin. (medscape.com)
- Of the three workers interviewed, none revealed health effects thought to be related to exposures at OmniSource other than the one worker with a diagnosis of argyria. (cdc.gov)
Conjunctiva3
- Local argyria shows in limited regions of the body, such as patches of skin, parts of the mucous membrane or the conjunctiva. (wikipedia.org)
- Argyrosis has been used particularly in referring to argyria of the conjunctiva, but the usage has never been consistent and cannot be relied on except where it has been explicitly specified. (wikipedia.org)
- Localized argyria occurs in the conjunctiva or oral mucous membrane after long-term topical treatment with silver salt solutions or short-contact acupuncture. (medscape.com)
Crambinae1
- The identity of Argyria lacteella (Fabricius, 1794) (Lepidoptera, Pyraloidea, Crambinae), synonyms, and related species revealed by morphology and DNA capture in type specimens. (msstate.edu)
Salts3
- Argyria results from prolonged contact with or ingestion of silver salts. (medscape.com)
- Universal argyria can develop after long-term systemic treatment with drugs that contain silver salts. (medscape.com)
- An intake of elemental silver, silver dust or silver compounds, over exposure to silver salts - typically industrial exposure or medication causes Argyria. (naturalcurefor.com)
Exposure5
- Argyria or argyrosis is a condition caused by excessive exposure to chemical compounds of the element silver, or to silver dust. (wikipedia.org)
- Argyria worsens and builds up as exposure to silver continues, and does not resolve once exposure stops because the silver molecules cannot be removed from the skin and other tissues. (wikipedia.org)
- However, the level of silver in the air and the length of exposure that caused argyria in these workers is not known. (wikipedia.org)
- [ 7 , 8 ] Great individual variability exists in the length of exposure and total dose needed to result in argyria. (medscape.com)
- Argyria has become a rare dermatosis, mainly because of the avoidance of silver-containing compounds as medicinals and a decrease in occupational exposure in the silver industry. (medscape.com)
Occurs3
- Argyria occurs in people who ingest or inhale silver in large quantities over a long period (several months to many years). (wikipedia.org)
- A permanent and irreversible metallic tinge occurs in the skin of patients with argyria. (medscape.com)
- This difference in electric charge is very important in understanding how argyria occurs. (wgpeters.com)
Symptom3
- The most dramatic symptom of argyria is that the skin turns blue or blue-grey. (wikipedia.org)
- The most evident symptom if Argyria is that the skin turns to blue or bluish-grey colored. (naturalcurefor.com)
- The most evident symptom of Argyria is grey or black staining of skin. (naturalcurefor.com)
Bianchi1
- Bianchi et al report a possible genetic predisposition for argyria. (medscape.com)
Ingestion2
- Argyria secondary to ingestion of homemade silver solution. (medscape.com)
- Lo and behold, Argyria , a condition caused by the ingestion of unfathomable amounts of silver, can actually turn people blue. (flavorwire.com)
Acupuncture1
- Tanita Y, Kato T, Hanada K, Tagami H. Blue macules of localized argyria caused by implanted acupuncture needles. (medscape.com)
Occupational2
- [ 9 ] Argyria also happens as an occupational disease in workers who prepare artificial pearls or who are employed in the cutting and polishing of silver (absorption of silver dust). (medscape.com)
- Harker JM, Hunter D: Occupational Argyria British J Derm & Syphil Nov. 1935 p. 441-455. (rosemaryjacobs.com)
Intake1
- Certain research suggests that excess intake of improperly made silver products may result in argyria, which is a skin condition where the skin turns blue. (wrinkle-free-skin-tips.com)
Medication1
- Bryant BL: Argyria resulting from intranasal medication. (rosemaryjacobs.com)
Cure1
- Is there a cure for argyria? (rosemaryjacobs.com)
Tissues2
- Tissues such as those found in the skin and eyes can become gray permanently in a process called argyria. (wbir.com)
- Long-term use of drugs containing silver can cause some areas of the skin and other body tissues, including in the eye, to permanently turn gray or blue-gray, which is called "argyria. (fda.gov)
Drops1
- Localised argyria often results from topical use of substances containing silver, such as some kinds of eye drops. (wikipedia.org)
Deposits1
- Selenium and kidney deposits in experimental argyria. (cdc.gov)
Clinical1
- All 5 patients presented with the typical clinical and histologic features of localized argyria. (qxmd.com)
Smallest1
- the smallest amount of silver reported to produce generalized argyria in humans ranges from 4-5 g to 20-40 g. (medscape.com)
Result1
- Generalized argyria results from chronically swallowing or inhaling silver compounds, either for home medicinal purposes, or as a result of working with silver or silver compounds. (wikipedia.org)
People2
- Have people gotten argyria from 'modern CS? (rosemaryjacobs.com)
- Also people who have Argyria. (inherentlyfunny.com)
Gray2
- Argyria is characterized by gray to gray-black staining of the skin and mucous membranes produced by silver deposition. (medscape.com)
- Localized argyria is uncommon and presents clinically as asymptomatic slate gray macules or blue macules resembling blue nevi. (qxmd.com)
Start1
- Argyria may start as generalized or local Argyria. (naturalcurefor.com)
Common1
- The histologic features of localized argyria include swollen and homogenized collagen bundles resembling ochronosis, "pseudo-ochronosis," which may be more common than previously recognized. (qxmd.com)
Patients1
- The purpose of this study is to report a series of 5 patients with localized argyria with the histologic feature of "pseudo-ochronosis. (qxmd.com)
Local1
- It may take the form of generalized argyria or local argyria. (wikipedia.org)
Body2
- Generalized argyria affects large areas over much of the visible surface of the body. (wikipedia.org)
- There is a whole body of medical literature on argyria and silver. (rosemaryjacobs.com)
Long1
- The terms argyria and argyrosis have long been used interchangeably, with argyria being used more frequently. (wikipedia.org)
Large3
- Argyria has also been attributed to surgical and dental procedures such as silver amalgam-tattooing, silver sutures used in abdominal surgery, and silver-coated large prostheses. (medscape.com)
- By ingesting large amounts of a high concentration silver salt, the individual acquired argyria. (lifeguardimmuneshop.com)
- Isn't argyria only caused by large particles of silver? (rosemaryjacobs.com)