A permanent ashen-gray discoloration of the skin, conjunctiva, and internal organs resulting from long-continued use of silver salts. (Dorland, 27th ed)

Longitudinal medical surveillance showing lack of progression of argyrosis in a silver refiner. (1/14)

Silver is a recognized cause of argyrosis and argyria. This case report describes blood silver levels and longitudinal ophthalmological examination in a previously reported case of argyrosis over a 5-year period.  (+info)

Long-term effects of Ag-containing alloys on mucous tissue present in biopsy samples. (2/14)

The aim of this study was to investigate the long-term effects of alloys containing silver (mainly Ag-Sn alloy) on oral mucous tissue. We observed biopsy tissue specimens from patients diagnosed as having amalgam tattoo and/or metal pigmentation by light and electron microscopy and electron-probe microanalysis (EPMA). In most cases, Ag-Sn alloy was present in the tissue but it could not be confirmed if the alloy originated from amalgam. Distributions of both Ag-S and Ag-Sn have typical patterns. Most Ag forms Ag2S and is stably deposited in three patterns along the collagen, basement membrane, and fibrous cells without inducing any host reaction. On the other hand, Sn forms large granules that contain Ag, S, C, N, P, and Ca, and is in soft state in the tissue. Tissue reactions to the alloy become weaker as time passes.  (+info)

Immunolocalization of HLA-DR and metallothionein on amalgam tattoos. (3/14)

Despite studies concerning toxic reactions related to amalgam components in the literature, few studies have been devoted to evaluate local noxious effects of amalgam tattoos (AT) on biological tissues. In addition, little is known about activation of inflammatory cells by mucosa-implanted amalgam debris. Tissue reaction to AT depends on the particle size. Human leukocyte antigen DR (HLA-DR) is an activation marker of inflammatory cells associated with antigen presentation. Metallothioneins (MT) are proteins involved with metal detoxication, including mercury and silver. The purpose of the present study was to investigate the immunolocalization of HLA-DR and MT in AT with large or powdered particles. Paraffin-embedded AT tissue blocks were sectioned and subjected to immunohistochemistry for HLA-DR and MT localization. The results demonstrated a dense mononuclear inflammatory infiltrate associated with large and powdered debris and positivity for HLA-DR and MT in inflammatory cells. While blood vessel walls and connective fibers impregnated with powdered particles were negative for HLA-DR, they were positive for MT. In addition, wherever epithelial basement membrane impregnation by powdered amalgam particles was observed, a strong positivity for MT was detected. These findings demonstrate that residual elements of AT still have noxious local effects over tissues.  (+info)

Exposure-related health effects of silver and silver compounds: a review. (4/14)

A critical review of studies examining exposures to the various forms of silver was conducted to determine if some silver species are more toxic than others. The impetus behind conducting this review is that several occupational exposure limits and guidelines exist for silver, but the values for each depend on the form of silver as well as the individual agency making the recommendations. For instance, the American Conference of Governmental Industrial Hygienists has established separate threshold limit values for metallic silver (0.1 mg/m3) and soluble compounds of silver (0.01 mg/m3). On the other hand, the permissible exposure limit (PEL) recommended by the Occupational Safety and Health Administration and the Mine Safety and Health Administration and the recommended exposure limit set by the National Institute for Occupational Safety and Health is 0.01 mg/m3 for all forms of silver. The adverse effects of chronic exposure to silver are a permanent bluish-gray discoloration of the skin (argyria) or eyes (argyrosis). Most studies discuss cases of argyria and argyrosis that have resulted primarily from exposure to the soluble forms of silver. Besides argyria and argyrosis, exposure to soluble silver compounds may produce other toxic effects, including liver and kidney damage, irritation of the eyes, skin, respiratory, and intestinal tract, and changes in blood cells. Metallic silver appears to pose minimal risk to health. The current occupational exposure limits do not reflect the apparent difference in toxicities between soluble and metallic silver; thus, many researchers have recommended that separate PELs be established.  (+info)

Silver deposition and tissue staining associated with wound dressings containing silver. (5/14)

Argyria is the general term used to denote a clinical condition in which excessive administration and deposition of silver causes a permanent irreversible gray-blue discoloration of the skin or mucous membranes. The amount of discoloration usually depends on the route of silver delivery (ie, oral or topical administration) along with the body's ability to absorb and excrete the administered silver compound. Argyria is accepted as a rare dermatosis but once silver particles are deposited, they remain immobile and may accumulate during the aging process. Topical application of silver salts (eg, silver nitrate solution) may lead to transient skin staining. To investigate their potential to cause skin staining, two silver-containing dressings (Hydrofiber and nanocrystalline) were applied to human skin samples taken from electively amputated lower limbs. The potential for skin discoloration was assayed using atomic absorption spectroscopy. When the dressings were hydrated with water, a significantly higher amount of silver was released from the nanocrystalline dressing compared to the Hydrofiber dressing (P <0.005), which resulted in approximately 30 times more silver deposition. In contrast, when saline was used as the hydration medium, the release rates were low for both dressings and not significantly different (silver deposition was minimal). Controlling the amount of silver released from silver-containing dressings should help reduce excessive deposition of silver into wound tissue and minimize skin staining.  (+info)

Quantitative near infrared spectroscopic analysis of Q-Switched Nd:YAG treatment of generalized argyria. (6/14)

 (+info)

Argyria -- case report. (7/14)

 (+info)

Argyria mimicking a blue nevis: dermoscopy features. (8/14)

 (+info)

Argyria is a rare, cosmetic condition that results from excessive exposure to silver and its compounds, leading to the accumulation of silver particles in various tissues of the body, particularly the skin. The most noticeable symptom of argyria is the development of a blue-gray or slate-gray discoloration of the skin, mucous membranes, and eyes. This condition is usually permanent and not harmful to one's health, but it can cause significant psychological distress due to its impact on appearance.

The primary causes of argyria are long-term use or misuse of silver-containing medications, dietary supplements, or topical products that contain silver compounds like silver nitrate, silver sulfadiazine, and colloidal silver. Prolonged exposure to silver dust in occupational settings can also lead to argyria.

It is important to note that argyria should not be confused with generalized silver toxicity or acute silver poisoning, which can have more severe health consequences.

It may take the form of generalized argyria or local argyria. Generalized argyria affects large areas over much of the visible ... The terms argyria and argyrosis have long been used interchangeably, with argyria being used more frequently. Argyrosis has ... "Rosemary's Story." Rosemary Jacobs explains her argyria; includes photographs. Accessed February 24, 2007. "Systemic Argyria ... Local argyria shows in limited regions of the body, such as patches of skin, parts of the mucous membrane or the conjunctiva. ...
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Argyria is a skin condition due to exposure to silver. Argyria may also refer to: Argyria (moth), a genus of moth Argyria ( ... Pontus), a town of ancient Pontus, now in Turkey Argyria (Troad), a town of the ancient Troad, now in Turkey This ... disambiguation page lists articles associated with the title Argyria. If an internal link led you here, you may wish to change ...
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... is a moth in the family Crambidae. It was described by Harrison Gray Dyar Jr. in 1913. It is found in Brazil ...
... is a moth in the family Crambidae. It was described by Harrison Gray Dyar Jr. in 1914. It is found in Panama ...
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... , the mother-of-pearl moth, is a moth in the family Crambidae. It was described by Zeller in 1872. It is ... Argyriini (Lepidoptera: Crambidae) of Mississippi and Alabama with a redescription of Argyria rufisignella (Zeller). Jl. Lep. ...
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... is a moth in the family Crambidae. It was described by Zeller in 1877. It is found in Panama. "global ...
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... is a moth in the family Crambidae. It was described by Arthur Gardiner Butler in 1878, and is found in Jamaica ...
Argyria (Ancient Greek: Ἀργυρία) was a town located in the ancient Troad on the right bank of the Aesepus River (modern Gönen ... 1854-1857). "Argyria". Dictionary of Greek and Roman Geography. London: John Murray. 39°45′01″N 27°13′20″E / 39.750179°N ... Gustav Hirschfeld: Argyria 1.(in German) In: Realencyclopädie der classischen Altertumswissenschaft (RE). Vol. II,1, Stuttgart ...
... is a moth in the family Crambidae. It was described by Schaus in 1922. It is found in Cuba. "global ...
... is a moth in the family Crambidae. It was described by Stanisław Błeszyński in 1962. It is found in Paraná, ...
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... is a moth in the family Crambidae. It was described by Zeller in 1839. It is found in Brazil. "global ...
Argyria argyrodis Dyar, 1914 Argyria argyrostola (Hampson, 1919) Argyria centrifugens Dyar, 1914 Argyria contiguella (Zeller, ... Argyria subtilis C. Felder, R. Felder & Rogenhofer, 1875 Argyria supposita Dyar, 1914 Argyria tripsacas (Dyar, 1921) Argyria ... 1913 Argyria multifacta Dyar, 1914 Argyria nummulalis Hübner, 1818 Argyria opposita Zeller, 1877 Argyria oxytoma Meyrick, 1932 ... 1913 Argyria divisella Walker, 1866 Argyria hannemanni Błeszyński, 1960 Argyria heringi Błeszyński, 1960 Argyria insons C. ...
It may take the form of generalized argyria or local argyria. Generalized argyria affects large areas over much of the visible ... The terms argyria and argyrosis have long been used interchangeably, with argyria being used more frequently. Argyrosis has ... "Rosemarys Story." Rosemary Jacobs explains her argyria; includes photographs. Accessed February 24, 2007. "Systemic Argyria ... Local argyria shows in limited regions of the body, such as patches of skin, parts of the mucous membrane or the conjunctiva. ...
Argyria is characterized by gray to gray-black staining of the skin and mucous membranes produced by silver deposition. ... Argyria results from prolonged contact with or ingestion of silver salts. ... Argyria results from prolonged contact with or ingestion of silver salts. Argyria is characterized by gray to gray-black ... encoded search term (Argyria) and Argyria What to Read Next on Medscape ...
Argyria » Argyria gonogramma - Hodges#5463.1 (Argyria gonogramma) ... Species Argyria gonogramma - Hodges#5463.1. The information below is based on images submitted and identified by contributors. ...
Argyria centrifugens Dyar, 1914. Taxonomic Notes:. Argyria centrifugens Dyar, 1914 is now recognized within the North American ... Argyria gonogramma Dyar, 1915 has labial palpi white dorsally; the subapical coastal dash is not followed by a subapical ... Argyria lacteella (Fabricius, 1794) has labial palpi white dorsally; a subapical coastal dash is followed by a subapical ... The identity of Argyria lacteella (Fabricius, 1794) (Lepidoptera, Pyraloidea, Crambinae), synonyms, and related species ...
Familial generalized argyria.. Luca Bianchi, Augusto Orlandi, Alessandro Di Stefani, Roberto Ricci, Sergio Chimenti. Archives ...
BACKGROUND: Localized argyria is uncommon and presents clinically as asymptomatic slate gray macules or blue macules resembling ... OBJECTIVE: The purpose of this study is to report a series of 5 patients with localized argyria with the histologic feature of ... Localized argyria with pseudo-ochronosis.. Leslie Robinson-Bostom, David Pomerantz, Caroline Wilkel, Russell Mader, Lisa Lerner ... RESULTS: All 5 patients presented with the typical clinical and histologic features of localized argyria. Ochre swollen and ...
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A Cure for Argyria: The Formula. 3 Vitamin E 1000 mg 100% Natural d-alpha Tocopheryl 1 Selenium 100mcg yeast free 2 vegetarian ... He also reversed the argyria. Many have long discussed the possibility of using Vitamin E, Selenium, and other supplements with ... By ingesting large amounts of a high concentration silver salt, the individual acquired argyria. It was likely a bit more ... The link will be readily found from our current document on Argyria. - Jason ...
About Argyria. Copyright © 2014 W.G.Peters/cgcsforum.com. Argyria is the gray/blue discoloration of the skin caused by the ... Many purveyors of colloidal silver say that ionic silver cannot cause argyria because ions are the smallest size and cannot get ... This difference in electric charge is very important in understanding how argyria occurs. Human cells require certain ions for ...
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Curve-lined Argyria. Argyria auratella. Observation date: July 07, 2022 Submitted by: robpendergast ...
Argyria There is a general concern that the use of colloidal silver may cause a condition known as argyria. Argyria is the ...
Diagnosis: Argyria. Were not sure how to diagnose Roger Klotzs reverse Oompa Loompa syndrome, so well just blame that on too ... Lo and behold, Argyria, a condition caused by the ingestion of unfathomable amounts of silver, can actually turn people blue. ...
It is likely that many exposures to silver are necessary to develop argyria. Once you have argyria, it is permanent. However, ... Doctors call this condition "argyria." Argyria occurs in people who eat or breathe in silver compounds over a long period ( ... Argyria that covers the entire body is not seen following skin contact with silver compounds, although the skin may change ... However, the level of silver in the air and the length of exposure that caused argyria in these workers is not known. It is ...
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The request was prompted by concerns about one employee who had been diagnosed as having argyria, a blue-grey discoloration of ... it is unlikely that the lesion represents localized argyria. NIOSH investigators concluded that employees in the PMR facility ... revealed health effects thought to be related to exposures at OmniSource other than the one worker with a diagnosis of argyria ...
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Kwon, H.B.; Lee, J.H.; Lee, S.H.; Lee, A.Y.; Choi, J.S.; Ahn, Y.S. A case of argyria following colloidal silver ingestion. Ann ... Ah, E.; Lee, W.S.; Kim, K.M.; Kim, S.Y. Occupational generalized argyria after exposure to aerosolized silver. J. Dermatol. ... The most common condition is argyria in which silver is stored under the skin, leaving it with a grayish tinge [128-130]. ... Mayr, M.; Kim, M.J.; Warner, D.; Hopfer, H.; Schroeder, J.; Mihatsch, M.J. Argyria and decreased kidney function: Are silver ...
Argyria and Decreased Kidney Function: Are Silver Compounds Toxic to the Kidney?;. Kidney Involvement in Multicentric Castleman ...
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Argyria. Argyria or argyrosis is a condition caused by excessive exposure to chemical compounds of the element silver, or to ...
argyria - A discoloration of the skin wherein the skin turns a blue-grey color as a result of over exposure to certain forms of ... Due to the high concentration of large silver particles these products are known to cause argyria, a condition that causes the ... Argyria is known to be caused by ingesting; 1) silver salts (compounds) such as silver nitrate, 2) high concentrations of ionic ... "Argyria is not caused by true silver colloids which consist of nanometer sized particles of silver in pure water. ...
Silver compounds can be absorbed in the circulatory system and cause argyria. ...
... and when you understand how argyria develops in the first place, it makes sense that you wouldnt get argyria from AgNPs ... He did not turn blue or get argyria.. I myself have been using AgNPs as needed for years and I have not turned blue. Even ... The person who is famous for argyria is Paul Karason, but at the time that he was popular, he was making his own silver at home ... What ever he was making, it was capable of causing argyria, but he was taking massive amounts of it everyday. He kept taking ...
Colloidal silver (and other silver products) can cause argyria, a permanent blue-gray discoloration of the skin and other ...
Hill WR, Montgomery H: Argyria Arch Derm Syphil 1941;44:588-99. Hill WR, Pillsbury DM: Argyria: The Pharmacology of Silver, ... Site Index , Argyria Photos , Silver Fraud , My Story , Naturopaths , FAQs , Links , E-mail Copyright © 1998 Rosemary Jacobs. ... Bryant BL: Argyria resulting from intranasal medication. Arch Otolaryngol 31:127-139, 1940. Collosols - British Colloids ... Harker JM, Hunter D: Occupational Argyria British J Derm & Syphil Nov. 1935 p. 441-455. Hartman RJ: Colloid Chemistry lst ...
  • Argyria is the gray/blue discoloration of the skin caused by the ingestion of certain types of silver preparations. (wgpeters.com)
  • The request was prompted by concerns about one employee who had been diagnosed as having argyria, a blue-grey discoloration of the skin, mucous membranes, and/or eyes resulting from prolonged silver exposure. (cdc.gov)
  • argyria - A discoloration of the skin wherein the skin turns a blue-grey color as a result of over exposure to certain forms of silver. (silver-colloids.com)
  • The most common is argyria, a build-up of silver in the body's tissues causing a bluish-gray discoloration of the skin, which is usually permanent. (nih.gov)
  • Chronic ingestion or inhalation of silver preparations (especially colloidal silver) can lead to argyria in the skin and other organs. (wikipedia.org)
  • Argyria following the use of dietary supplements containing colloidal silver protein. (medscape.com)
  • Many purveyors of colloidal silver say that ionic silver cannot cause argyria because ions are the smallest size and cannot get 'stuck' within cells. (wgpeters.com)
  • Argyria There is a general concern that the use of colloidal silver may cause a condition known as argyria. (highppmsilver.com)
  • Gaul LE, Staud AH: Seventy cases of generalized argyria following organic and colloidal silver medication, including biospectrometric analysis of ten cases. (rosemaryjacobs.com)
  • This will tell you how many DROPS (i.e., from an eye dropper) of colloidal silver you can take each day, safely, for a lifetime, without fear of ending up with argyria (i.e., skin-staining). (blogspot.com)
  • Once you end up with argyria - the blue-gray skin-staining that typifies long-term excessive usage of colloidal silver - you can't switch gears and start blaming others for it. (blogspot.com)
  • As far as scientists can tell, those deposits may just be like the blue skin people get when they consume too much colloidal silver - the skin color may help doctors diagnose a person with argyria but giving the patient a spray tan isn't going to improve their health. (skepchick.org)
  • Your product allegedly contains silver and water yet you tell me it cannot cause argyria. (rosemaryjacobs.com)
  • The diagnosis of argyria is established by skin biopsy with formaldehyde-fixed paraffin-embedded sections stained with hematoxylin-eosin. (medscape.com)
  • Of the three workers interviewed, none revealed health effects thought to be related to exposures at OmniSource other than the one worker with a diagnosis of argyria. (cdc.gov)
  • Local argyria shows in limited regions of the body, such as patches of skin, parts of the mucous membrane or the conjunctiva. (wikipedia.org)
  • Argyrosis has been used particularly in referring to argyria of the conjunctiva, but the usage has never been consistent and cannot be relied on except where it has been explicitly specified. (wikipedia.org)
  • Localized argyria occurs in the conjunctiva or oral mucous membrane after long-term topical treatment with silver salt solutions or short-contact acupuncture. (medscape.com)
  • The identity of Argyria lacteella (Fabricius, 1794) (Lepidoptera, Pyraloidea, Crambinae), synonyms, and related species revealed by morphology and DNA capture in type specimens. (msstate.edu)
  • Argyria results from prolonged contact with or ingestion of silver salts. (medscape.com)
  • Universal argyria can develop after long-term systemic treatment with drugs that contain silver salts. (medscape.com)
  • An intake of elemental silver, silver dust or silver compounds, over exposure to silver salts - typically industrial exposure or medication causes Argyria. (naturalcurefor.com)
  • Argyria or argyrosis is a condition caused by excessive exposure to chemical compounds of the element silver, or to silver dust. (wikipedia.org)
  • Argyria worsens and builds up as exposure to silver continues, and does not resolve once exposure stops because the silver molecules cannot be removed from the skin and other tissues. (wikipedia.org)
  • However, the level of silver in the air and the length of exposure that caused argyria in these workers is not known. (wikipedia.org)
  • [ 7 , 8 ] Great individual variability exists in the length of exposure and total dose needed to result in argyria. (medscape.com)
  • Argyria has become a rare dermatosis, mainly because of the avoidance of silver-containing compounds as medicinals and a decrease in occupational exposure in the silver industry. (medscape.com)
  • Argyria occurs in people who ingest or inhale silver in large quantities over a long period (several months to many years). (wikipedia.org)
  • A permanent and irreversible metallic tinge occurs in the skin of patients with argyria. (medscape.com)
  • This difference in electric charge is very important in understanding how argyria occurs. (wgpeters.com)
  • The most dramatic symptom of argyria is that the skin turns blue or blue-grey. (wikipedia.org)
  • The most evident symptom if Argyria is that the skin turns to blue or bluish-grey colored. (naturalcurefor.com)
  • The most evident symptom of Argyria is grey or black staining of skin. (naturalcurefor.com)
  • Bianchi et al report a possible genetic predisposition for argyria. (medscape.com)
  • Argyria secondary to ingestion of homemade silver solution. (medscape.com)
  • Lo and behold, Argyria , a condition caused by the ingestion of unfathomable amounts of silver, can actually turn people blue. (flavorwire.com)
  • Tanita Y, Kato T, Hanada K, Tagami H. Blue macules of localized argyria caused by implanted acupuncture needles. (medscape.com)
  • [ 9 ] Argyria also happens as an occupational disease in workers who prepare artificial pearls or who are employed in the cutting and polishing of silver (absorption of silver dust). (medscape.com)
  • Harker JM, Hunter D: Occupational Argyria British J Derm & Syphil Nov. 1935 p. 441-455. (rosemaryjacobs.com)
  • Certain research suggests that excess intake of improperly made silver products may result in argyria, which is a skin condition where the skin turns blue. (wrinkle-free-skin-tips.com)
  • Tissues such as those found in the skin and eyes can become gray permanently in a process called argyria. (wbir.com)
  • Long-term use of drugs containing silver can cause some areas of the skin and other body tissues, including in the eye, to permanently turn gray or blue-gray, which is called "argyria. (fda.gov)
  • Localised argyria often results from topical use of substances containing silver, such as some kinds of eye drops. (wikipedia.org)
  • Selenium and kidney deposits in experimental argyria. (cdc.gov)
  • All 5 patients presented with the typical clinical and histologic features of localized argyria. (qxmd.com)
  • the smallest amount of silver reported to produce generalized argyria in humans ranges from 4-5 g to 20-40 g. (medscape.com)
  • Generalized argyria results from chronically swallowing or inhaling silver compounds, either for home medicinal purposes, or as a result of working with silver or silver compounds. (wikipedia.org)
  • Argyria is characterized by gray to gray-black staining of the skin and mucous membranes produced by silver deposition. (medscape.com)
  • Localized argyria is uncommon and presents clinically as asymptomatic slate gray macules or blue macules resembling blue nevi. (qxmd.com)
  • The histologic features of localized argyria include swollen and homogenized collagen bundles resembling ochronosis, "pseudo-ochronosis," which may be more common than previously recognized. (qxmd.com)
  • The purpose of this study is to report a series of 5 patients with localized argyria with the histologic feature of "pseudo-ochronosis. (qxmd.com)
  • It may take the form of generalized argyria or local argyria. (wikipedia.org)
  • Generalized argyria affects large areas over much of the visible surface of the body. (wikipedia.org)
  • There is a whole body of medical literature on argyria and silver. (rosemaryjacobs.com)
  • The terms argyria and argyrosis have long been used interchangeably, with argyria being used more frequently. (wikipedia.org)
  • Argyria has also been attributed to surgical and dental procedures such as silver amalgam-tattooing, silver sutures used in abdominal surgery, and silver-coated large prostheses. (medscape.com)
  • By ingesting large amounts of a high concentration silver salt, the individual acquired argyria. (lifeguardimmuneshop.com)
  • Isn't argyria only caused by large particles of silver? (rosemaryjacobs.com)