New phenylethanoid glycosides from Bacopa monniera. (1/20)
Three new phenylethanoid glycosides, viz. monnierasides I-III (1-3) along with the known analogue plantainoside B were isolated from the glycosidic fraction of Bacopa monniera. Their structures were elucidated mainly on the basis of two dimensional (2D) NMR spectral analyses. (+info)Bacopasides III-V: three new triterpenoid glycosides from Bacopa monniera. (2/20)
Three new saponins, designated as bacopasides III, IV and V have been isolated from Bacopa monniera WETTST. and their structures have been elucidated as 3-O-alpha-L-arabinofuranosyl (1-->2)-beta-D-glucopyranosyl jujubogenin (1), 3-O-beta-D-glucopyranosyl (1-->3)-alpha-L-arabinopyranosyl jujubogenin (2) and 3-O-beta-D-glucopyranosyl (1-->3)-alpha-L-arabinopyranosyl pseudojujubogenin (3) mainly on the basis of two dimensional (2D) NMR and other spectral analyses. (+info)Bacosterol glycoside, a new 13,14-seco-steroid glycoside from Bacopa monnieri. (3/20)
A new sterol glycoside, bacosterol-3-O-beta-D-glucopyranoside along with bacopasaponin-C, bacopaside-I, bacopaside-II, bacosterol, bacosine and luteolin-7-O-beta-glucopyranoside have been isolated from Bacopa monnieri. Their structures were elucidated mainly on the basis of IR, 1D, 2D NMR (HMQC, HMBC, COSY), HR-ESI-QTOF-MS and EI mass spectral studies. (+info)Estimation of twelve bacopa saponins in Bacopa monnieri extracts and formulations by high-performance liquid chromatography. (4/20)
A simple and sensitive reversed phase high performance liquid chromatographic (HPLC) method has been developed for the simultaneous determination of twelve bacopa saponins present in the extracts of the Indian Medicinal Plant, Bacopa monnieri. The separation was achieved on a reversed phase C(18) column (Luna C(18)), 5 microm by isocratic elution with 0.05 M sodium sulphate buffer (pH 2.3) and acetonitrile (68.5 : 31.5, v/v) as the mobile phase at a flow rate of 1.0 ml/min with an operating temperature of 30 degrees C. The method was validated for linearity, precision, intra- and inter-day precision and accuracy. Several Bacopa samples (plant materials, extracts and commercial formulations) were successfully analyzed. Major bacopasaponins were bacosides A(3) (3), bacopaside II (4), bacopaside I (5), bacopaside X (6), bacopasaponin C (7), bacopaside N2 (9) and the minor components were bacopasaponin F (1), bacopasaponin E (2), bacopaside N1 (8) bacopaside III (10), bacopaside IV (11) and bacopaside V (12). The total saponin content in the samples, plant materials and extracts varied from 5.1 to 22.17% and 1.47 to 66.03 mg/capsule or tablet in the commercial formulations. (+info)Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. (5/20)
(+info)Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans. (6/20)
(+info)Effect of induced oxidative stress and herbal extracts on acid phosphatase activity in lysosomal and microsomal fractions of midgut tissue of the silkworm, Bombyx mori. (7/20)
(+info)Enhancement of basolateral amygdaloid neuronal dendritic arborization following Bacopa monniera extract treatment in adult rats. (8/20)
(+info)Bacopa, also known as Bacopa monnieri or water hyssop, is a medicinal herb that has been used in traditional Ayurvedic medicine for centuries. It is native to wetlands in southern and eastern India, Australia, Europe, Africa, and North and South America.
The active compounds in bacopa are called bacosides, which have been shown to have antioxidant, anti-inflammatory, and neuroprotective properties. Bacopa has been traditionally used to improve memory, learning, and concentration, and is also believed to have calming and anxiety-reducing effects.
Clinical studies on bacopa have shown mixed results, with some studies suggesting that it may improve cognitive function in tasks that require sustained attention and working memory, while other studies have found no significant benefits. However, bacopa is generally considered safe when taken at recommended doses, and may be worth trying as a natural supplement for cognitive enhancement or stress relief.
It's important to note that bacopa should not be used as a substitute for conventional medical treatment, and anyone considering taking it should first consult with their healthcare provider.