A fungal infection that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.
A genus of onygenacetous mitosporic fungi whose perfect state is Ajellomyces (see ONYGENALES). The species Blastomyces dermatitidis (perfect state Ajellomyces dermatitidis) causes blastomycosis.
Pulmonary diseases caused by fungal infections, usually through hematogenous spread.
MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME).
Infection resulting from inhalation or ingestion of spores of the fungus of the genus HISTOPLASMA, species H. capsulatum. It is worldwide in distribution and particularly common in the midwestern United States. (From Dorland, 27th ed)
whoa, buddy! I'm just a friendly AI and I don't have access to real-time databases or personal data, so I can't provide medical definitions or any other specific information about individuals, places, or things. But I can tell you that I couldn't find any recognized medical definition for "Wisconsin" - it's a state in the United States, not a medical term!
Substances of fungal origin that have antigenic activity.
A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.
Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
Superficial infections of the skin or its appendages by any of various fungi.
A mycosis affecting the skin, mucous membranes, lymph nodes, and internal organs. It is caused by Paracoccidioides brasiliensis. It is also called paracoccidioidal granuloma. Superficial resemblance of P. brasiliensis to Blastomyces brasiliensis (BLASTOMYCES) may cause misdiagnosis.
Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.

Blastomycosis acquired occupationally during prairie dog relocation--Colorado, 1998. (1/191)

On August 31, 1998, two suspected cases of fungal pneumonia were reported to the Boulder County (Colorado) Health Department (BCHD). Both patients were immunocompetent, otherwise healthy adults working for the City of Boulder Open Space (CBOS) program on a prairie dog relocation project. This report summarizes the epidemiologic investigation by BCHD, the Colorado Department of Public Health and Environment, and CDC; the findings indicate that these two persons acquired blastomycosis in Colorado, which is outside the area where the disease is endemic.  (+info)

Targeted gene disruption reveals an adhesin indispensable for pathogenicity of Blastomyces dermatitidis. (2/191)

Systemic fungal infections are becoming more common and difficult to treat, yet the pathogenesis of these infectious diseases remains poorly understood. In many cases, pathogenicity can be attributed to the ability of the fungi to adhere to target tissues, but the lack of tractable genetic systems has limited progress in understanding and interfering with the offending fungal products. In Blastomyces dermatitidis, the agent of blastomycosis, a respiratory and disseminated mycosis of people and animals worldwide, expression of the putative adhesin encoded by the WI-1 gene was investigated as a possible virulence factor. DNA-mediated gene transfer was used to disrupt the WI-1 locus by allelic replacement, resulting in impaired binding and entry of yeasts into macrophages, loss of adherence to lung tissue, and abolishment of virulence in mice; each of these properties was fully restored after reconstitution of WI-1 by means of gene transfer. These findings establish the pivotal role of WI-1 in adherence and virulence of B. dermatitidis yeasts. To our knowledge, they offer the first example of a genetically proven virulence determinant among systemic dimorphic fungi, and underscore the value of reverse genetics for studies of pathogenesis in these organisms.  (+info)

Endemic mycoses: a treatment update. (3/191)

Endemic mycoses remain a major public health problem in several countries and they are becoming increasingly frequent with the spread of HIV infection. Amphotericin B remains the drug of choice during the acute stage of life-threatening endemic mycoses occurring in both immunocompetent and immunocompromised hosts. Ketoconazole is effective in non-AIDS patients with non-life-threatening histoplasmosis, blastomycosis, or paracoccidioidomycosis. Itraconazole is the treatment of choice for non-life-threatening Histoplasma capsulatum or Blastomyces dermatitidis infections occurring in immunocompetent individuals and is the most efficient secondary prophylaxis of histoplasmosis in AIDS patients. Itraconazole is also effective in lymphocutaneous and visceral sporotrichosis, in paracoccidioidomycosis, for Penicillum marneffei infection, and is an alternative to amphotericin B for Histoplasma duboisii infection. Coccidioidomycosis may be effectively treated with prolonged and sometimes life-long itraconazole or fluconazole therapy. Fluconazole has relatively poor efficacy against histoplasmosis, blastomycosis and sporotrichosis. New antifungal agents have been tested in vitro or in animal models and may soon be evaluated in clinical trials.  (+info)

Thoracic blastomycosis and empyema. (4/191)

Blastomycosis is endemic in river valley areas of the southeastern and Midwestern United States. Pulmonary manifestations include chronic cough and pleuritic pain. Radiographic appearance of the infection can mimic bronchogenic lung carcinoma. Pleural effusion is rarely associated with this pulmonary infection, and empyema has not been previously reported. We report a case of pulmonary and pleural Blastomyces dermatitidis infection presenting as empyema thoracis. Diagnosis and treatment were attained with video-assisted thoracoscopic (VATS) pleural and lung biopsy and debridement.  (+info)

Disseminated blastomycosis in a rhesus monkey (Macaca mulatta). (5/191)

An 8-year-old male rhesus monkey (Macaca mulatta) died following a 6-day illness consisting of progressive depression, anorexia, labored abdominal breathing, coughing, and tachypnea. Gross necropsy findings included severe multifocal (miliary) granulomatous pneumonia, granulomatous splenitis, and multifocal cerebral abscesses. Histologic examination revealed 10-15-microm broad-based budding organisms within pyogranulomatous inflammatory lesions in the lung, tracheobronchial lymph node, brain, spleen, and liver. The distribution of extrapulmonary lesions was intermediate between that described for dogs and that described for humans. These findings were consistent with blastomycosis, which is previously unreported in nonhuman primates.  (+info)

T-Cell epitopes and human leukocyte antigen restriction elements of an immunodominant antigen of Blastomyces dermatitidis. (6/191)

Humans infected with the dimorphic fungus Blastomyces dermatitidis develop strong T-lymphocyte responses to WI-1, an immunodominant antigen that has been shown to elicit protective immunity in mice. In the present study, the T-cell epitopes of WI-1 and human leukocyte antigen (HLA) restricting elements that display them were investigated. Peripheral blood mononuclear cells (PBMC) from 37 patients with a confirmed history of blastomycosis were tested for a response to WI-1 in primary proliferation assays; PBMC from 35 (95%) responded. Six patients whose PBMC proliferated strongly in response to WI-1 (defined as a stimulation index greater than 50) were tested further for responses to subcloned, recombinant fragments of the antigen. These patients responded chiefly to sequences within the N terminus and the 25-amino-acid tandem repeat. Cloned CD4(+) T cells from an infected individual were used to delineate more precisely the peptide epitopes in the fragments and HLA restricting elements that present them. A majority of the T-cell clones recognized an epitope spanning amino acids 149 to 172 within the N terminus, displayed by HLA-DR 15. A minority of the clones, which have been shown to perform a cytolytic function in vitro, recognized an epitope in the tandem repeat displayed by HLA-DPw4, an uncommon restricting element. Tandem repeat epitopes required display by the beta chain of DPw4 heterodimers. Thus, human T cells with different functions in vitro also recognize distinct regions of WI-1, raising the possibility that HLA restricting elements that present them could modulate immunity during blastomycosis by selection and display of WI-1 peptides.  (+info)

Jorge Lobo's disease: experimental inoculation in Swiss mice. (7/191)

Sixty-four isogenic Swiss mice were intradermically inoculated in both hind foot pads. The inocula, consisting of fungal suspensions from biopsies obtained from Jorge Lobo's Disease patients, had the total number of fungi and the viability index determined using a Neubauer chamber and the fluorescein diacetate-ethidium bromide technique (FD-EB), respectively. The animals were sacrificed at times ranging from ten days to eighteen months after inoculation. The cellular infiltrate, mainly consisting of macrophages containing fungi, increased progressively up to end of the study; however, no macroscopic alterations were observed in the inoculated feet. After nine months, small numbers of Langhans' giant cells started to appear in the infiltrate. A considerable number of fungi was observed at the end of the experimental period, but only a few were viable when stained by the FD-EB technique. This fact suggests that there is a multiplication of fungal cells, which are destroyed by the macrophages but remain in the tissue for a long time due perhaps to the difficulties in their elimination. These findings led us to conclude that in spite of the maintenance of the infection in these animals, Swiss mice cannot be considered an ideal model to study Jorge Lobo's Disease. However, the authors call attention to the possibility of other mouse strains being more susceptible to Paracoccidioides loboi.  (+info)

Molecular epidemiology of Blastomyces dermatitidis. (8/191)

The inhalation of conidia of Blastomyces dermatitidis, a fungus found in soil, causes disease in humans and animals. We studied the genetic diversity of this pathogen by extracting DNA yeasts and analyzing them with a polymerase chain reaction (PCR)-based typing system we developed, which used restriction fragment analysis of amplicons from the regions between the rDNA repeats and allowed us to class isolates into 3 major groups. Strains were further differentiated by use of PCR fingerprinting with 3 different primers. Fifty-nine isolates collected over 35 years from 15 regions (United States, India, Africa, Canada) were analyzed. Genotypic groups A, B, and C contained 17, 23, and 19 isolates, which were divided into 5, 15, and 12 types, respectively. All 16 isolates from North America in group A were from the upper midwestern United States or Canada, whereas 0 of 20 isolates from the southeastern United States were in group A. Studies of the largest collection from 1 locale (Eagle River, WI), revealed that the soil isolates studied were not responsible for the majority of cases in this outbreak, as previously proposed, and that >1 strain was present in the environment and in patients. Overall, these results provide a tool for the epidemiological study of blastomycosis and illuminate the genetic and geographic diversity of this important pathogen.  (+info)

Blastomycosis is a fungal infection caused by the inhalation of spores of the fungus Blastomyces dermatitidis. It primarily affects the lungs but can also spread to other parts of the body, such as the skin, bones, and central nervous system. The initial symptoms of blastomycosis may include cough, fever, chest pain, and difficulty breathing. If left untreated, the infection can become severe and potentially life-threatening. Treatment typically involves antifungal medications, such as itraconazole or amphotericin B.

"Blastomyces" is a genus of fungi that can cause a pulmonary or systemic infection known as blastomycosis in humans and animals. The fungus exists in the environment, particularly in damp soil and decomposing organic matter, and is typically found in certain regions of North America. Infection occurs when a person inhales spores of the fungus, which can lead to respiratory symptoms such as cough, fever, and chest pain. The infection can also disseminate to other parts of the body, causing various symptoms depending on the organs involved.

Fungal lung diseases, also known as fungal pneumonia or mycoses, refer to a group of respiratory disorders caused by the infection of fungi in the lungs. These fungi are commonly found in the environment, such as soil, decaying organic matter, and contaminated materials. People can develop lung diseases from fungi after inhaling spores or particles that contain fungi.

There are several types of fungal lung diseases, including:

1. Aspergillosis: This is caused by the Aspergillus fungus and can affect people with weakened immune systems. It can cause allergic reactions, lung infections, or invasive aspergillosis, which can spread to other organs.
2. Cryptococcosis: This is caused by the Cryptococcus fungus and is usually found in soil contaminated with bird droppings. It can cause pneumonia, meningitis, or skin lesions.
3. Histoplasmosis: This is caused by the Histoplasma capsulatum fungus and is commonly found in the Ohio and Mississippi River valleys. It can cause flu-like symptoms, lung infections, or disseminated histoplasmosis, which can spread to other organs.
4. Blastomycosis: This is caused by the Blastomyces dermatitidis fungus and is commonly found in the southeastern and south-central United States. It can cause pneumonia, skin lesions, or disseminated blastomycosis, which can spread to other organs.
5. Coccidioidomycosis: This is caused by the Coccidioides immitis fungus and is commonly found in the southwestern United States. It can cause flu-like symptoms, lung infections, or disseminated coccidioidomycosis, which can spread to other organs.

Fungal lung diseases can range from mild to severe, depending on the type of fungus and the person's immune system. Treatment may include antifungal medications, surgery, or supportive care. Prevention measures include avoiding exposure to contaminated soil or dust, wearing protective masks in high-risk areas, and promptly seeking medical attention if symptoms develop.

Central nervous system (CNS) fungal infections refer to invasive fungal diseases that affect the brain and/or spinal cord. These types of infections are relatively uncommon but can be serious and potentially life-threatening, especially in individuals with weakened immune systems due to conditions such as HIV/AIDS, cancer, or organ transplantation.

There are several types of fungi that can cause CNS infections, including:

1. Candida species: These are yeast-like fungi that can cause a range of infections, from superficial to systemic. When they invade the CNS, they can cause meningitis or brain abscesses.
2. Aspergillus species: These are mold-like fungi that can cause invasive aspergillosis, which can affect various organs, including the brain.
3. Cryptococcus neoformans: This is a yeast-like fungus that primarily affects people with weakened immune systems. It can cause meningitis or brain abscesses.
4. Coccidioides species: These are mold-like fungi that can cause coccidioidomycosis, also known as Valley Fever. While most infections are limited to the lungs, some people may develop disseminated disease, which can affect the CNS.
5. Histoplasma capsulatum: This is a mold-like fungus that causes histoplasmosis, which primarily affects the lungs but can disseminate and involve the CNS.

Symptoms of CNS fungal infections may include headache, fever, altered mental status, seizures, stiff neck, and focal neurologic deficits. Diagnosis typically involves a combination of clinical evaluation, imaging studies (such as MRI or CT), and laboratory tests (such as cerebrospinal fluid analysis or fungal cultures). Treatment usually involves long-term antifungal therapy, often with a combination of drugs, and may also include surgical intervention in some cases.

Histoplasmosis is a pulmonary and systemic disease caused by the dimorphic fungus Histoplasma capsulatum. It is typically acquired through the inhalation of microconidia from contaminated soil, particularly in areas associated with bird or bat droppings. The infection can range from asymptomatic to severe, depending on factors like the individual's immune status and the quantity of inhaled spores.

In acute histoplasmosis, symptoms may include fever, cough, fatigue, chest pain, and headache. Chronic or disseminated forms of the disease can affect various organs, such as the liver, spleen, adrenal glands, and central nervous system, leading to more severe complications. Diagnosis often involves serological tests, cultures, or histopathological examination of tissue samples. Treatment depends on the severity and dissemination of the disease, with antifungal medications like itraconazole or amphotericin B being commonly used for moderate to severe cases.

I'm sorry for any confusion, but "Wisconsin" is a U.S. state located in the Midwest and is not a medical term or condition. If you have any medical questions or terms you would like defined, I'd be happy to help with those!

Fungal antigens are substances found on or produced by fungi that can stimulate an immune response in a host organism. They can be proteins, polysaccharides, or other molecules that are recognized as foreign by the host's immune system. Fungal antigens can be used in diagnostic tests to identify fungal infections, and they can also be targets of immune responses during fungal infections. In some cases, fungal antigens may contribute to the pathogenesis of fungal diseases by inducing inflammatory or allergic reactions. Examples of fungal antigens include the cell wall components of Candida albicans and the extracellular polysaccharide galactomannan produced by Aspergillus fumigatus.

Itraconazole is an antifungal medication used to treat various fungal infections, including blastomycosis, histoplasmosis, aspergillosis, and candidiasis. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting the integrity and function of these membranes. Itraconazole is available in oral and intravenous forms for systemic use and as a topical solution or cream for localized fungal infections.

Medical Definition:
Itraconazole (i-tra-KON-a-zole): A synthetic triazole antifungal agent used to treat various fungal infections, such as blastomycosis, histoplasmosis, aspergillosis, and candidiasis. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes, leading to disruption of their integrity and function. Itraconazole is available in oral (capsule and solution) and intravenous forms for systemic use and as a topical solution or cream for localized fungal infections.

Coccidioidomycosis is a fungal infection caused by the inhalation of spores of the Coccidioides species, mainly C. immitis and C. posadasii. These fungi are commonly found in the soil of dry regions such as the southwestern United States, Mexico, and Central and South America.

The infection often begins when a person inhales the microscopic spores, which can lead to respiratory symptoms resembling a common cold or pneumonia. Some people may develop more severe symptoms, especially those with weakened immune systems. The infection can disseminate to other parts of the body, causing skin lesions, bone and joint inflammation, meningitis, or other complications in rare cases.

Diagnosis typically involves a combination of clinical evaluation, imaging studies, and laboratory tests such as fungal cultures, histopathological examination, or serological tests to detect antibodies against Coccidioides antigens. Treatment depends on the severity of the infection and the patient's immune status. Antifungal medications like fluconazole, itraconazole, or amphotericin B are commonly used for treating coccidioidomycosis. Preventive measures include avoiding inhaling dust in endemic areas, especially during excavation or construction activities.

Antifungal agents are a type of medication used to treat and prevent fungal infections. These agents work by targeting and disrupting the growth of fungi, which include yeasts, molds, and other types of fungi that can cause illness in humans.

There are several different classes of antifungal agents, including:

1. Azoles: These agents work by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. Examples of azole antifungals include fluconazole, itraconazole, and voriconazole.
2. Echinocandins: These agents target the fungal cell wall, disrupting its synthesis and leading to fungal cell death. Examples of echinocandins include caspofungin, micafungin, and anidulafungin.
3. Polyenes: These agents bind to ergosterol in the fungal cell membrane, creating pores that lead to fungal cell death. Examples of polyene antifungals include amphotericin B and nystatin.
4. Allylamines: These agents inhibit squalene epoxidase, a key enzyme in ergosterol synthesis. Examples of allylamine antifungals include terbinafine and naftifine.
5. Griseofulvin: This agent disrupts fungal cell division by binding to tubulin, a protein involved in fungal cell mitosis.

Antifungal agents can be administered topically, orally, or intravenously, depending on the severity and location of the infection. It is important to use antifungal agents only as directed by a healthcare professional, as misuse or overuse can lead to resistance and make treatment more difficult.

Dermatomycoses are a group of fungal infections that affect the skin, hair, and nails. These infections are caused by various types of fungi, including dermatophytes, yeasts, and molds. Dermatophyte infections, also known as tinea, are the most common type of dermatomycoses and can affect different areas of the body, such as the scalp (tinea capitis), beard (tinea barbae), body (tinea corporis), feet (tinea pedis or athlete's foot), hands (tinea manuum), and nails (tinea unguium or onychomycosis). Yeast infections, such as those caused by Candida albicans, can lead to conditions like candidal intertrigo, vulvovaginitis, and balanitis. Mold infections are less common but can cause skin disorders like scalded skin syndrome and phaeohyphomycosis. Dermatomycoses are typically treated with topical or oral antifungal medications.

Paracoccidioidomycosis is a deep fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis, which is endemic in certain regions of Central and South America. The infection primarily affects the lungs but can disseminate to other organs such as the lymph nodes, mucous membranes, skin, and central nervous system.

The disease typically manifests in two clinical forms: acute/subacute (also known as juvenile) and chronic. The acute form tends to occur in younger individuals and is characterized by widespread dissemination of the fungus throughout the body, often leading to severe symptoms and a higher mortality rate. The chronic form, on the other hand, typically affects adult males and presents with pulmonary lesions and slow-growing granulomatous skin or mucosal ulcers.

Diagnosis of paracoccidioidomycosis is usually made by identifying the characteristic "pilot's wheel" or "Mickey Mouse ear" shaped yeast cells in tissue samples, sputum, or other bodily fluids using direct examination, culture, or histopathological methods. Treatment typically involves antifungal therapy with medications such as trimethoprim-sulfamethoxazole, itraconazole, or amphotericin B, depending on the severity and extent of infection.

Amphotericin B is an antifungal medication used to treat serious and often life-threatening fungal infections. It works by binding to the ergosterol in the fungal cell membrane, creating pores that lead to the loss of essential cell components and ultimately cell death.

The medical definition of Amphotericin B is:

A polyene antifungal agent derived from Streptomyces nodosus, with a broad spectrum of activity against various fungi, including Candida, Aspergillus, Cryptococcus, and Histoplasma capsulatum. Amphotericin B is used to treat systemic fungal infections, such as histoplasmosis, cryptococcosis, candidiasis, and aspergillosis, among others. It may be administered intravenously or topically, depending on the formulation and the site of infection.

Adverse effects associated with Amphotericin B include infusion-related reactions (such as fever, chills, and hypotension), nephrotoxicity, electrolyte imbalances, and anemia. These side effects are often dose-dependent and may be managed through careful monitoring and adjustment of the dosing regimen.

... was first described by Thomas Caspar Gilchrist in 1894, as a skin disease. Because of this, blastomycosis is ... Less frequently, blastomycosis also occurs in Africa, the Middle East, India, and western North America. Blastomycosis also ... However, the overall risk of blastomycosis in cats is 28 to 100 times lower than in dogs. Cases of blastomycosis have also been ... Although blastomycosis is especially dangerous for those with weak immune systems, most people diagnosed with blastomycosis ...
... is a cutaneous condition characterized by large verrucous plaques with elevated borders and ... multiple pustules.: 255, 272 List of cutaneous conditions pyoderma blastomycosis Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo ...
Ferri, Fred (2015). "Blastomycosis". Ferri's Clinical Advisor. Philadelphia: Mosby (Elsevier). pp. 198.e2-198.e4. ISBN ... which cause blastomycosis, that do not tend to stimulate acute inflammation. Alternatively, cold abscesses are typical in ...
With F. C. Bocobo.) Cryptococcosis and blastomycosis. Ann. New York Acad. Sci. 50: 1299-1314. 1950. The Laboratory of Medical ... Hopkins.) The fungi of blastomycosis and coccidioidal granuloma. Arch. Derm. Syph. 30: 385-400. 1934. The terminology of the ... Benham, Rhoda W. (September 1950). "Cryptococcosis and Blastomycosis". Annals of the New York Academy of Sciences. 50 (10): ...
Dwight, P.J.; Naus, M; Sarsfield, P; Limerick, B (2000). "An outbreak of human blastomycosis: the epidemiology of blastomycosis ... Blastomycosis is generally readily treatable with systemic antifungal drugs once it is correctly diagnosed; however, delayed ... The Canadian range of B. dermatitidis shows an abundance of blastomycosis in broad areas north and south of the St. Lawrence ... The internal organs of the mice are then checked microscopically for evidence of blastomycosis. Needless to say, the cost and ...
February 2006). "Blastomycosis in Ontario, 1994-2003". Emerging Infectious Diseases. 12 (2): 274-9. doi:10.3201/eid1202.050849 ... lakes or rivers that infect otherwise healthy visitors with the often deadly disease blastomycosis. His most cited works are on ...
Crich A (June 1932). "Blastomycosis of the Gingiva and Jaw". Canadian Medical Association Journal. 26 (6): 662-5. PMC 402380. ...
North American blastomycosis James, William D.; Elston, Dirk; Treat, James R.; Rosenbach, Misha A.; Neuhaus, Isaac (2019). "13 ... Paracoccidioidomycosis (PCM), also known as South American blastomycosis, is a fungal infection that can occur as a mouth and ...
Furcolow, Michael L.; Balows, A.; Menges, R. W.; Pickar, D.; McClellan, J. T.; Saliba, A. (1966). "Blastomycosis: An important ... "Some Factors Affecting Survival in Systemic Blastomycosis". Diseases of the Chest. 54: 285-291. doi:10.1378/chest.54.Supplement ...
Blastomycosis, caused by Blastomyces species including Blastomyces dermatitidis, is a fungal disease that affects both dogs and ... Probst, Sarah (1999). "Blastomycosis-Fungal Disease Common in Outdoor Dogs". Pet Columns. UIUC College of Veterinary Medicine. ...
Linder KA, Kauffman CA, Miceli MH (2023). "Blastomycosis: A review of mycological and clinical aspects". J Fungi (Basel). 9 (1 ... They are the causative agents of blastomycosis, a systemic mycosis in immunocompromised patients. Blastomyces Gilchrist & W.R. ...
... of fungi in blastomycosis and histoplasmosis. Arch Pathol Lab Med 1982; 106:440-41. Ziehl-Neelsen protocol (PDF ...
This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. It may be given by ... It is also licensed for use in blastomycosis, sporotrichosis, histoplasmosis, and onychomycosis. Itraconazole is over 99% ...
Blastomycosis-like pyoderma List of cutaneous conditions Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). ...
Fungal infections may lead to chromoblastomycosis, blastomycosis, mucormycosis, and dermatophytosis. Other numerous arthropod, ...
This includes candidiasis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and tinea ...
... the cause of North American blastomycosis, and blastomyces brasiliensis, the cause of South American blastomycosis." A portion ... the cause of North American blastomycosis, and blastomyces brasiliensis, the cause of South American blastomycosis (PhD). Duke ... Friedman, L; Conant, N.F. (1953). "Immunological studies on the etiologic agents of North and South American blastomycosis". ... of her research, "Immunological studies on the etiologic agents of North and South American blastomycosis" was published in ...
Restrepo, M; Restrepo A (1970). "Paracoccidiomycosis (South American blastomycosis): a study of 39 cases observed in Medellin, ... The pathological features of paracoccidioidomycosis are similar to those seen in coccidioidomycosis and blastomycosis. However ... Blastomycosis dermatitidis. The yeast-like form of P. brasiliensis contains multiple nuclei, a porous two-layered nuclear ... bone and prostate set the clinical picture of paracoccidioidomycosis apart from that of blastomycosis. Martinez, Roberto; ...
Histoplasmosis, like blastomycosis, may disseminate haematogenously to infect internal organs and tissues, but it does so in a ... Unlike blastomycosis, histoplasmosis is a recognized AIDS-defining illness in people with HIV infection; disseminated ...
In his early part of career, he undertook research at Northwestern University on blastomycosis. He later worked on Rocky ...
Endemic mycoses such as histoplasmosis, blastomycosis, coccidiomycosis and paracoccidioidomycosis can cause a fever of unknown ... Disseminated granulomatoses such as tuberculosis, histoplasmosis, coccidioidomycosis, blastomycosis and sarcoidosis are ...
Meningitis is an unusual manifestation of blastomycosis and can be very difficult to diagnose. Cryptococcus (Cryptococcal ...
Some types such as blastomycosis, cryptococcus, coccidioidomycosis and histoplasmosis, affect people who live or visit certain ... Some fungal infections such as coccidioidomycosis, histoplasmosis, and blastomycosis can present with fever, cough, and ... ICD-11 codes include: 1F20 Aspergillosis 1F21 Basidiobolomycosis 1F22 Blastomycosis 1F23 Candidosis 1F24 Chromoblastomycosis ... Systemic fungal infections include histoplasmosis, cryptococcosis, coccidioidomycosis, blastomycosis, mucormycosis, ...
In the early part of his career, Ricketts undertook research at Northwestern University on blastomycosis. He later worked in ...
Blastomycosis* is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans. Dogs are ten times ...
... blastomycosis, and cat-scratch disease. Examples of noninfectious[clarification needed] granulomatous diseases are sarcoidosis ... and granulomas with numerous neutrophils suggest blastomycosis, granulomatosis with polyangiitis, aspiration pneumonia, or cat- ...
In this phase, it can be confused with fungal infections such as blastomycosis and chromoblastomycosis.[citation needed] The ...
Other conditions that appear similar include tuberculosis, blastomycosis, sporotrichosis, chicken pox, Kaposi's sarcoma and ...
"North American Blastomycosis"). Entamoeba histolytica, a parasitic protozoan, is sometimes known to cause mouth ulcers through ...
The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, ...
Blastomycosis was first described by Thomas Caspar Gilchrist in 1894, as a skin disease. Because of this, blastomycosis is ... Less frequently, blastomycosis also occurs in Africa, the Middle East, India, and western North America. Blastomycosis also ... However, the overall risk of blastomycosis in cats is 28 to 100 times lower than in dogs. Cases of blastomycosis have also been ... Although blastomycosis is especially dangerous for those with weak immune systems, most people diagnosed with blastomycosis ...
Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. The fungus is found in decaying wood ... Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. The fungus is found in decaying wood ... You can get blastomycosis by contact with moist soil, most commonly where there is rotting wood and leaves. The fungus enters ... Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. The fungus is found in decaying wood ...
Visit blastomycosis resources from various state health and hospital systems. ... Louisiana Department of Health and Hospitals - Blastomycosis pdf icon[PDF - 3 pages]external icon ... Minnesota Department of Health - Blastomycosis (Blastomyces dermatitidis)external icon. *Wisconsin Department of Health ... Michigan Department of Community Health - Blastomycosis pdf icon[PDF - 2 pages]external icon ...
Blastomycosis is a fungal infection caused by inhalation of aerosolized conidia (spores) of Blastomyces dermatitidis. Clinical ... blastomycosis is often referred to as North American blastomycosis, which is an obsolete term. The term European blastomycosis ... Blastomycosis can be endemic or sporadic. Most cases of blastomycosis occur in the United States and Canada, although ... Likewise, South American blastomycosis (ie, Brazilian blastomycosis) is an older name for paracoccidioidomycosis, a chronic, ...
Blastomycosis, hereafter called blasto, is an infection caused by the fungus Blastomyces dermatitidis (B. dermatitidis). ...
Blastomycosis [blasʺto-mi-koʹsis]. From the Greek blastós ("germ, sprout") and mykēs ("fungus, mushroom"), this invasive fungal ... Clinical and laboratory update on blastomycosis. Clin Microbiol Rev. 2010;23:367-81 . DOIPubMedGoogle Scholar ... Etymologia: Blastomycosis. Volume 20, Number 11-November 2014. Article Views: 214. Data is collected weekly and does not ... Henry R. Etymologia: Blastomycosis. Emerging Infectious Diseases. 2014;20(11):1794. doi:10.3201/eid2011.et2011.. ...
The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that ... Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of ... Calls/Webinars - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis​, Thursday ... Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis. *Preparing for the ...
Blastomycosis, 2015. Blastomycosis is caused by the dimorphic fungus Blastomyces dermatitidis, which exists as a mold in the ... Twenty-four (71%) cases were hospitalized for a median of 6.5 days (range, 2 to 53 days). In 1 case, blastomycosis was a ... In 2015, there were 34 reported blastomycosis cases. This is similar to the 32 cases reported in 2014, and 34 in 2013. The ... For up to date information see,, Blastomycosis (Blastomyces dermatitidis). *Full issue,, Annual Summary of Communicable ...
Blastomycosis in Africa: a new case from Tunisia. M Jerray, A Hayouni, M Benzarti, N Klabi, A Garrouche ... Blastomycosis in Africa: a new case from Tunisia Message Subject (Your Name) has sent you a message from European Respiratory ... Although blastomycosis is prevalent in the North American continent, it occurs only sporadically in Africa. We describe a 42 yr ... The diagnosis of pulmonary blastomycosis was made at thoracotomy. This rather unusual disease in our areas caused a ...
The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that ... Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of ... Calls/Webinars - Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis​, Thursday ... Algorithms for Diagnosing the Endemic Mycoses Blastomycosis, Coccidioidomycosis, and Histoplasmosis. *Preparing for the ...
Blastomycosis occurs most commonly in humans, dogs, and cats, but cases have also been reported in a variety of non-domestic ... Fatal disseminated blastomycosis in a free-ranging American black bear (Ursus americanus). J Vet Diagn Infest. 2012;24:1125- ... Fatal blastomycosis in a captive walrus (Odobenus rosmarus, divergens). Proc Am Assoc Zoo Vet. 2002;1:399. ... Medical Management of Blastomycosis in a Wild-Born Young Polar Bear (Ursus maritimus) ...
Blastomycosis-like pyoderma: Novel use of potassium iodide ... Erratum: Blastomycosis-like pyoderma: Novel use of potassium ... Erratum: Blastomycosis-like pyoderma: Novel use of potassium iodide. Indian J Dermatol Venereol Leprol 2018;84:523. ... Borra SK, Peter DC, Balakrishnan N, Pulimood S, Bhindra M. Blastomycosis-like pyoderma: Novel use of potassium iodide. Indian J ... In the article titled "Blastomycosis-like pyoderma: Novel use of potassium iodide", published on pages 720-721, Issue 6, Volume ...
Blastomycosis - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional ... Symptoms and Signs of Blastomycosis Pulmonary blastomycosis Pulmonary blastomycosis may be asymptomatic or cause an acute, self ... Blastomycosis (Gilchrist Disease; North American Blastomycosis). By Paschalis Vergidis , MD, MSc, Mayo Clinic College of ... Extrapulmonary Blastomycosis (Bullae). Extrapulmonary blastomycosis may manifest in the skin or genitals. Skin lesions manifest ...
Computed tomography (CT) findings in a dog with intracranial blastomycosis were marked periventricular contrast enhancement of ... This is particularly true in dogs with systemic or ocular blastomycosis, which appear to be at higher risk of developing CNS ... CT is therefore recommended as a screening test for intracranial blastomycosis in dogs and also as an imaging modality for ... Computed tomography (CT) findings in a dog with intracranial blastomycosis were marked periventricular contrast enhancement of ...
Access Blastomycosis case definitions; uniform criteria used to define a disease for public health surveillance. ...
Blastomycosis is a fungal infection caused by inhalation of aerosolized conidia (spores) of Blastomyces dermatitidis. Clinical ... Blastomycosis has a propensity to mimic carcinoma. Pulmonary blastomycosis may resemble lung cancer, and blastomycosis ... encoded search term (Blastomycosis) and Blastomycosis What to Read Next on Medscape ... Blastomycosis Differential Diagnoses. Updated: Feb 18, 2015 * Author: Chidinma Chima-Okereke, MD; Chief Editor: Zab Mosenifar, ...
You should be aware of the symptoms of Blastomycosis. If you think your pet has this condition, you should see your family ...
Here you will find the medication for blastomycosis. ... Blastomycosis is a lung infection caused by the fungus ...
Blastomycosis. Blastomycosis is a systemic pyogranulomatous infection that primarily involves the lungs and arises after ... Blastomycosis of the central nervous system: a multicenter review of diagnosis and treatment in the modern era. Clin Infect Dis ... Vertebral blastomycosis with paravertebral abscess: report of eight cases and review of the literature. Clin Infect Dis. 1998; ... Blastomycosis of bone. A report of six cases. J Bone Joint Surg. 1982;64(7):1097-1101. ...
Izimpawu ze-Blastomycosis ezinjeni zingahluka kakhulu, kuye ngezitho ezithintekile. Nazi ezinye izimpawu ezivamile: ... Ukuxilongwa kwe-Blastomycosis Ezinjeni. *Ukwelashwa kanye nokubikezelwa kweCanine Blastomycosis*Ukuvimbela Blastomycosis ... Iyini i-Blastomycosis?. I-Blastomycosis i-systemic fungal infection ebangelwa umzimba I-Blastomyces dermatitidis. Isikhunta ... 4. Ingabe i-Blastomycosis ingenzeka ezinjeni?. Yebo, i-Blastomycosis ingaphinda ibuyele ezinjeni, ikakhulukazi uma inkambo ...
Blastomycosis (Blastomyces dermatitidis) is a systemic fungal infection acquired from soil, most notably in river valleys of ... Treatment of Blastomycosis predominantly relies on azole medications and is often prolonged, lasting months. The prognosis is ... Blastomycosis. In: Infectious Disease of the Dog and Cat, 3rd ed., 2006, p. 569-576 ... Antigen and antibody testing for the diagnosis of blastomycosis in dogs. J Vet Intern Med 2008;22:839-843. ...
Acute blastomycosis is typically found only in North America, and the clinical presentation of blastomycosis in nonendemic ... Sullivan D.C., & Nolan, III R.L. Sullivan, Donna C., and Rathel L. Nolan, III.BLASTOMYCOSIS. In: Kasper DL, Fauci AS. Kasper D. ... Sullivan D.C., & Nolan, III R.L. Sullivan, Donna C., and Rathel L. Nolan, III. "BLASTOMYCOSIS." Harrisons Infectious Diseases ... Sullivan D.C., & Nolan, III R.L. Sullivan, Donna C., and Rathel L. Nolan, III. (2017). Blastomycosis. Kasper DL, Fauci AS. ...
Blastomycosis. 6836 Blindness: see also. Vision and Anatomical Loss Both eyes, only light perception. 6062 ...
Paracoccidioides brasiliensis • South American Blastomycosis - endemic area Brazil, Venezuela, Columbia • Inhale infectious ... Well demarcated skin lesions are often seen in disseminated Blastomycosis. • Skin lesions are full of yeast cells. ...
Canine Ringworm is caused by an infectious fungus in hot, humid climates. Symptoms in Dogs vary and include small hairless lesions commonly found on the head. Treatment includes topical cream or oral antifungal medication.
Diagnostic Kit for Blastomycosis Blastomyces dermatitidis is a soil fungus found throughout the world, and is especially ...
Histoplasmosis, blastomycosis, and coccidioidomycosis. In: Steinbach WJ, Green MD, Michaels MG, Danziger-Isakov LA, Fisher BT, ...
fungal: blastomycosis (Blastomyces dermatitidis); candidiasis (Candida albicans); coccidioidomycosis (Coccidioides immitis/ ...
Blastomycosis. Discoid lupus erythematosus. Cutaneous anthrax. Histoplasmosis. Eczema. Lethal midline granuloma. Fungal skin ...
  • Because the symptoms are variable and nonspecific, blastomycosis is often not even considered in differential diagnosis until antibacterial treatment has failed, unless there are known risk factors or skin lesions. (wikipedia.org)
  • Blastomycosis should be considered in the differential diagnosis of an atypical pulmonary infection in regions where it is endemic, even in urban areas. (medscape.com)
  • Delays in diagnosis of pulmonary blastomycosis can be reduced if a higher clinical suspicion exists and there is earlier use of sputum potassium hydroxide (KOH) fungal smear, especially after a course of antibiotics has failed to result in clinical improvement. (medscape.com)
  • Blastomyces antigen detection for diagnosis and management of Blastomycosis. (medscape.com)
  • Participants will also be introduced to new clinical diagnostic algorithms to address these challenges and improve the timely diagnosis of blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
  • The patient received a diagnosis of primary cutaneous blastomycosis, which is caused by blastomyces species, dimorphic fungi found in the eastern half of the United States that typically grow in soil and detritus from wooded areas. (medizzy.com)
  • Culture and cytopathology are the gold standard for the diagnosis of blastomycosis. (medscape.com)
  • Blasto can affect virtually every system in a dog's body, so observation and a physical exam, including blood tests, are unlikely to point a veterinarian in the direction of a blastomycosis diagnosis. (medpdfarticles.com)
  • However, there are many cases that the disease is too advanced by the time we see the pet, and the medication can't kick in quick enough to save the dogDogs with suspected cases of blastomycosis need a thorough workup to arrive at the diagnosis as quickly as possible. (millcreekanimal.com)
  • We report the case of a 32-year-old man who after visiting Chicago, Illinois, USA, returned to India and received treatment for tuberculosis for 12 months before receiving the correct diagnosis of blastomycosis. (cdc.gov)
  • Diagnosis of blastomycosis involves identifying the fungal organism, and identifying organs that are affected. (vetster.com)
  • In regions where blastomycosis is endemic, the diagnosis should be considered in patients with pulmonary disease. (cdc.gov)
  • Pulmonary blastomycosis may resemble lung cancer, and blastomycosis osteomyelitis may resemble bony metastasis. (medscape.com)
  • Blastomycosis can be a subclinical illness with subsequent protection against progressive infection afforded by cellular immune mechanisms, but it may present with progressive disease with either pulmonary or extrapulmonary disease or both. (nih.gov)
  • Pulmonary blastomycosis. (nih.gov)
  • Blastomycosis organisms have a predilection for the respiratory tract, and pulmonary disease is the most common sign (88-94% of canine cases). (vin.com)
  • Chronic pulmonary blastomycosis is often misdiagnosed and treated as tuberculosis in disease-endemic and non-disease-endemic areas. (cdc.gov)
  • To report a case of possible amphotericin B-induced hepatotoxicity in a patient with pulmonary blastomycosis. (nih.gov)
  • A 26-year-old white man with life-threatening pulmonary blastomycosis developed elevation of his liver enzymes after the addition of amphotericin B to his initial itraconazole therapy. (nih.gov)
  • Histoplasmosis and blastomycosis. (medscape.com)
  • The endemic mycoses blastomycosis, coccidioidomycosis (Valley fever), and histoplasmosis are environmental fungal diseases that are frequently misdiagnosed. (cdc.gov)
  • Describe the epidemiology of blastomycosis, coccidioidomycosis, and histoplasmosis in the United States and the impact of delayed and underdiagnosed cases. (cdc.gov)
  • Discuss diagnostic challenges associated with blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
  • Identify populations clinicians should consider testing for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
  • Describe diagnostic tests clinicians should consider initially and after a negative test for blastomycosis, coccidioidomycosis, and histoplasmosis. (cdc.gov)
  • In some parts of the United States and the world, it is difficult to avoid breathing in fungal spores that cause infections like histoplasmosis, blastomycosis, or Valley fever. (cdc.gov)
  • The purpose of this Funding Opportunity Announcement is to support research activities that will contribute to the overall understanding of coccidioidomycosis, commonly known as Valley Fever, and other select endemic fungal diseases including histoplasmosis and blastomycosis. (nih.gov)
  • Blastomycosis is an infection caused by a fungus called Blastomyces . (cdc.gov)
  • Blastomycosis is an endemic fungal infection of North America that is caused by the thermally dimorphic fungus, Blastomyces dermatitidis . (medscape.com)
  • Blastomycosis is an infection caused by breathing in the Blastomyces dermatitidis fungus. (medlineplus.gov)
  • Blastomycosis is an endemic mycoses in the central United States caused by a dimorphic fungus, Blastomyces dermatitidis, that exists in nature in mycelial phase and converts to yeast phase at body temperature. (nih.gov)
  • Blastomycosis is a rare fungal infection caused by the fungus Blastomyces dermatitidis , which thrives in decomposing matter like leaves and wood or moist soil. (naturalpedia.com)
  • Symptoms of blastomycosis may not manifest until three to four weeks after the fungus is inhaled. (naturalpedia.com)
  • Blastomycosis, called blasto for short, is caused by fungus blastomyces dermatitidis . (medpdfarticles.com)
  • Simply put, blastomycosis is a very serious and potentially deadly illness that's caused by a fungus typically found in the soil near water ways or swampy areas. (medpdfarticles.com)
  • Blastomycosis is a disease in animals and people caused by the fungus Blastomyces dermatitidis. (millcreekanimal.com)
  • The blasto fungus like the eyes, as 20-50% of dogs with blastomycosis have eye lesions and these can quickly lead to blindness. (millcreekanimal.com)
  • Blastomycosis is a fungal infection in cats caused by the fungus Blastomyces dermatitidis , which is commonly found in soil around bodies of water. (vetster.com)
  • The causative agent of blastomycosis is the fungus Blastomyces dermatitidis . (vetster.com)
  • These individuals' symptoms began in January and February and early tests suggested that their illnesses might be blastomycosis, an infection caused by a fungus in the genus Blastomyces . (livescience.com)
  • In addition to these confirmed cases, the team has identified 74 probable cases, meaning people who showed blastomycosis symptoms and tested positive for antigen - identifiable bits of fungus in their blood - or antibodies - immune molecules that latch onto the fungus. (livescience.com)
  • exposed to areas where the fungus could be found, it might be important to ask your doctor to test for blastomycosis. (cdc.gov)
  • Blastomyces dermatitidis is the causal agent of blastomycosis , an invasive and often serious fungal infection found occasionally in humans and other animals in regions where the fungus is endemic. (wikidoc.org)
  • Lung symptoms are common, because the lungs are infected in 79% of blastomycosis cases. (wikipedia.org)
  • less than 50% of healthy people with blastomycosis have symptoms, while immunocompromised patients are especially likely to have the disease spread beyond the lungs to other organs like the skin and bones. (wikipedia.org)
  • Blastomycosis in the lungs may present a variety of symptoms, or no symptoms at all. (wikipedia.org)
  • Contact your provider if you have symptoms of blastomycosis. (medlineplus.gov)
  • Individuals infected with blastomycosis confined to the lungs and who are not suffering from severe symptoms often don't require treatment. (naturalpedia.com)
  • Sometimes blastomycosis of the lungs causes no symptoms or causes symptoms that disappear quickly and are not recognized. (msdmanuals.com)
  • Even then, symptoms of blastomycosis can get worse before they get better if there are massive amounts of dead yeast in the dog's system that the body must expel. (medpdfarticles.com)
  • ARDS is an uncommon but dangerous manifestation of blastomycosis. (wikipedia.org)
  • Chronic pneumonia is the dominant clinical manifestation of blastomycosis, although extrapulmonary disease is common, usually involving skin and subcutaneous tissue, bones and joints, the prostate gland, and the central nervous system (CNS). (medscape.com)
  • There are no routine measures to prevent blastomycosis, although there is promising experimental data involving the use of a live, attenuated vaccine. (medscape.com)
  • Blastomycosis: fungal infections of the lung update: 1989. (nih.gov)
  • Unlike most fungal infections, blastomycosis is not more common among people with AIDS. (msdmanuals.com)
  • Blastomycosis can cause skin, bone, muscle and brain infections. (millcreekanimal.com)
  • This case illustrates the imaging similarities between spinal blastomycosis, spinal tuberculosis, and other fungal infections as well as the need for biopsy to differentiate. (elsevierpure.com)
  • Development of a highly sensitive and specific blastomycosis antibody enzyme immunoassay using Blastomyces dermatitidis surface protein BAD-1. (medscape.com)
  • Blastomycosis, caused by Blastomyces dermatitidis , is a systemic fungal infection that affects dogs and cats. (vin.com)
  • Blastomycosis is a systemic pyogranulomatous infection usually caused by the inhalation of (spores) conidia of Blastomyces dermatitidis . (medscape.com)
  • Diana Khuu] Blastomycosis is a fungal disease caused by blastomyces dermatitidis. (cdc.gov)
  • Diana Khuu] We decided to do this study because, even though we know quite a bit about the biology and risk factors of infection by Blastomyces dermatitidis , the public health burden of blastomycosis deaths in the United States was unknown. (cdc.gov)
  • Blastomyces dermatitidis is the causal agent of blastomycosis , a potentially very serious disease that typically begins with a characteristically subtle pneumonia-like infection that may progress, after 1-6 months, to a disseminated phase that causes lesions to form in capillary beds throughout the body, most notably the skin, internal organs, central nervous system and bone marrow. (wikidoc.org)
  • Amphotericin B via intravenous administration is the suggested drug for severe or life-threatening blastomycosis (e.g. (naturalpedia.com)
  • Oral azoles, usually itraconazole or amphotericin B, are first-line treatment for blastomycosis depending on the severity of the disease, its clinical form, and the host's immune status. (medscape.com)
  • The hepatotoxicity resolved rapidly with discontinuation of the amphotericin B, and the blastomycosis was successfully treated with itraconazole alone. (nih.gov)
  • This case illustrates an unusual occurrence of hepatotoxicity associated with a short course of amphotericin B. Liver biopsy was compatible with drug-induced changes and showed no evidence of blastomycosis. (nih.gov)
  • People can get blastomycosis after breathing in the microscopic fungal spores from the air. (cdc.gov)
  • People can catch blastomycosis by breathing in Blastomyces spores from the air, but most people who breathe in the spores don't actually get sick, according to the CDC. (livescience.com)
  • In disseminated blastomycosis, the large Blastomyces yeast cells translocate from the lungs and are trapped in capillary beds elsewhere in the body, where they cause lesions. (wikipedia.org)
  • The typical verrucous or ulcerative cutaneous lesions of blastomycosis may mimic skin cancers, such as basal cell carcinoma and squamous cell carcinoma. (medscape.com)
  • The term North American blastomycosis , a commonly uses synonym, evolved to distinguish this disorder from the clinically similar South American blastomycosis, a disease caused by Paracoccidioides brasiliensis . (medscape.com)
  • Blastomycosis of the colon resembling clinically ulcerative colitis. (bmj.com)
  • Chronic blastomycosis should always be treated with systemic antifungal therapy, and oral itraconazole is the drug of choice for mild to moderate forms of the disease. (medscape.com)
  • Most cases of blastomycosis are usually diagnosed after the infection has become chronic. (cdc.gov)
  • Blastomycosis is a chronic infection characterized by a granulomatous and suppurative lesion. (mold-help.org)
  • Fine needle aspiration (FNA) of the adrenal mass and a subsequent vocal cord biopsy confirmed chronic widely disseminated blastomycosis. (globethics.net)
  • Individuals can get blastomycosis once the microscopic and airborne fungal spores are inhaled. (naturalpedia.com)
  • Blastomycosis has existed for millions of years but was first described by Thomas Caspar Gilchrist in 1894. (wikipedia.org)
  • Gilchrist first described blastomycosis in 1894, mistakenly attributing the disease to a protozoan. (medscape.com)
  • The fastest way to diagnose blastomycosis is direct identification of the broad based budding yeast forms under microscopy. (medscape.com)
  • Blastomycosis, also known as Gilchrist's disease, is a fungal infection, typically of the lungs, which can spread to brain, stomach, intestine and skin, where it appears as crusting purplish warty plaques with a roundish bumpy edge and central depression. (wikipedia.org)
  • Blastomycosis also affects a broad range of non-human mammals, and dogs in particular are an order of magnitude more likely to contract the disease than humans. (wikipedia.org)
  • The signature image of blastomycosis in textbooks is the indolent, verrucous or ulcerated dermal lesion seen in disseminated disease. (wikipedia.org)
  • Canine blastomycosis as a harbinger of human disease. (medscape.com)
  • Humans and animals like dogs, rats, and cats may contract blastomycosis, but the disease is rarely transmitted from human-to-human or animal-to-human. (naturalpedia.com)
  • As a result, the illness has usually progressed beyond the point of treatment and recovery by the time other illnesses or disease are ruled out and blastomycosis is diagnosed. (medpdfarticles.com)
  • His right eye looked normal at this visit.We collected a urine sample to test for a disease called blastomycosis. (millcreekanimal.com)
  • The human members of the family will be discussing blastomycosis with their physician to watch for any signs that they may have the disease. (millcreekanimal.com)
  • The clearer resulting identification of risk factors from national data may raise provider and community awareness of blastomycosis to make blastomycosis a diagnostic consideration in patients with lung disease. (cdc.gov)
  • For clinical aspects of the disease, see Blastomycosis . (wikidoc.org)
  • 1. Laryngeal carcinoma--or is it laryngeal blastomycosis. (nih.gov)
  • 2. Treatment of isolated laryngeal blastomycosis with ketoconazole. (nih.gov)
  • 9. Laryngeal presentation of blastomycosis. (nih.gov)
  • A case of blastomycosis with laryngeal involvement. (nih.gov)
  • A doctor diagnoses blastomycosis by sending a sample of sputum or infected tissue to a laboratory to be examined under a microscope and cultured. (msdmanuals.com)
  • Blastomycosis typically affects the lungs, causing difficulty breathing. (vetster.com)
  • A blastomycosis outbreak in Michigan's Upper Peninsula has sickened dozens of paper mill workers. (insider.com)
  • An unprecedented outbreak of the fungal infection blastomycosis among employees in a papermill in Michigan. (cdc.gov)
  • In the acute stage, blastomycosis may be misdiagnosed as bacterial pneumonia and sometimes as another illness. (cdc.gov)
  • Clinical and laboratory update on blastomycosis. (medscape.com)
  • Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America. (medscape.com)
  • Endemic blastomycosis in Mississippi: epidemiological and clinical studies. (medscape.com)
  • From Blastomycosis to Neuroblastoma, graduating seniors from the UW-Stevens Point clinical laboratory science program presented case and research studies at the annual CLS Capstone Day. (uwsp.edu)
  • Blastomycosis manifests as a primary lung infection in about 79% of cases. (wikipedia.org)
  • Diana Khuu is an author on the article, "Blastomycosis Mortality Rates, United States, 1990 to 2010. (cdc.gov)
  • After looking at blastomycosis deaths from 1990 to 2010 death certificate data, we found that blastomycosis deaths were more likely in older people, men, and Native Americans, or blacks. (cdc.gov)
  • It was not until 1951, following the detailed pathologic description of blastomycosis by Schwarz and Baum, [ 9 ] that it was discovered that most cases of the disorder were acquired via the respiratory, not cutaneous, route of inoculation. (medscape.com)
  • It is a common infection among dogs, especially in areas where blastomycosis is widespread. (naturalpedia.com)
  • Although blastomycosis is especially dangerous for those with weak immune systems, most people diagnosed with blastomycosis have healthy immune systems. (wikipedia.org)
  • When a patient, especially one with a weakened immune system, has severe blastomycosis, the infection can spread from the lungs to other parts of the body like the skin, bones and joints, and the central nervous system (CNS), or to the brain and the spinal cord. (naturalpedia.com)
  • Composite photomicrograph of a tissue specimen from a patient with blastomycosis infection shows an abundance of large budding cells that had been configured in chains. (medscape.com)
  • Patient with blastomycosis, India, 2014. (cdc.gov)
  • Blastomycosis can occur in people who have a normal immune system. (msdmanuals.com)
  • Because of strong suspicion of a fungal infection, probably blastomycosis, and considering the patient's stay in Chicago, anti-TB therapy was replaced with itraconazole at a dose of 200 mg 2×/d. (cdc.gov)
  • Blastomycosis medication » Which medications for blastomycosis? (compharms.com)
  • Patients with mild to moderate disseminated blastomycosis without central nervous system involvement should be treated for 6 months. (medscape.com)
  • Blastomycosis requires prolonged treatment. (medscape.com)
  • For that reason, we sent Spike for a visit with a veterinary ophthalmologist (yes veterinary medicine has many specialty fields….these veterinarians have gone through an additional 3-4 years of intense education to earn their specialty degrees).The ophthalmologist agreed that the biggest concern was blastomycosis, so aggressive treatment was initiated that day. (millcreekanimal.com)
  • A few days later, the test came back positive for blastomycosis, and we were already a couple days ahead of the game….our treatment plan was on course. (millcreekanimal.com)
  • Blastomycosis is difficult to treat, and many treatment protocols require several months of antifungal therapy. (vetster.com)
  • Blastomycosis is an uncommon infection that primarily affects outdoor cats. (vetster.com)
  • If untreated, many cases progress over a period of months to years to become disseminated blastomycosis. (wikipedia.org)
  • It was seen in 9 of 72 blastomycosis cases studied in northeast Tennessee. (wikipedia.org)
  • Notes from the field: Blastomycosis cases occurring outside of regions with known endemicity - New York, 2007-2017. (medscape.com)
  • Most cases of blastomycosis primarily affect the lungs. (vetster.com)
  • Health officials have reported 19 confirmed cases and 74 probable cases of blastomycosis linked to a paper mill. (livescience.com)
  • In states where blastomycosis is reportable, each year there are about 1 to 2 cases reported per 100,000 people. (livescience.com)
  • After PHDM learned of the initial cases of blastomycosis among paper mill employees, the department launched an investigation. (livescience.com)
  • As of April 7, the investigators had identified 19 confirmed cases of blastomycosis. (livescience.com)
  • Establishing blastomycosis as the cause of pneumonia is often difficult, and most patients received multiple antibiotic courses before being diagnosed. (medscape.com)
  • Thus, blastomycosis affects primarily the lungs, but the fungi occasionally spread through the bloodstream to other areas of the body, most commonly the skin. (msdmanuals.com)
  • Other forms of blastomycosis include draining skin sores or abscesses, swollen lymph nodes, and seizures. (vetster.com)
  • Blastomycosis may affect the skin, eyes, and nervous system of cats. (vetster.com)