Bryonia
Arnica
Encyclopedias as Topic
Urtica dioica
Naval Medicine
Evaluation of anti-inflammatory activity of chloroform extract of Bryonia laciniosa in experimental animal models. (1/4)
The anti-inflammatory effect of the leaves of Bryonia laciniosa was evaluated using carrageenan, dextran, histamine, serotonin induced rat paw oedema and cotton pellet induced granuloma (chronic) models in rats. In mice, carrageenan peritonitis test was performed for the extract by oral administration. The chloroform extract of Bryonia laciniosa (CEBL) exhibited significant anti-inflammatory effect at the dose 50, 100 and 200 mg/kg. Maximum inhibition (52.4%) was noted at the dose of 200 mg/kg after 3 h of drug treatment in carrageenan induced paw oedema, whereas the indomethacin (standard drug) produced 62.1% of inhibition. The extract exhibited significant anti-inflammatory activity in dextran induced paw oedema in a dose dependent manner. The extract also exhibited significant inhibition on the hind paw oedema in rats caused by histamine and serotonin respectively. In the chronic model (cotton pellet induced granuloma) the CEBL (200 mg/kg) and standard drug showed decreased formation of granuloma tissue by 50.1 and 57.3% (p<0.001) respectively. The extract also inhibited peritoneal leukocyte migration in mice. Thus, the present study revealed that the chloroform extract of Bryonia laciniosa exhibited significant anti-inflammatory activity in the tested models. (+info)Plant-based formulation in the management of chronic obstructive pulmonary disease: a randomized double-blind study. (2/4)
BACKGROUND: A randomized double-blind placebo controlled clinical study was undertaken to investigate the safety and efficacy of a plant-based formulation (DCBT1234-Lung KR), which earlier through 2 trials was found to improve FEV1 and the quality of life of COPD patients. OBJECTIVE: The efficacy of DCBT1234-Lung KR was assessed using pulmonary function tests, arterial blood gas (ABG) analyses and the clinical symptoms of COPD in a 6-month study period against a matching placebo and a biomedical drug combination (salbutamol+theophylline+bromhexine). METHODS: One hundred and five subjects aged between 35 and 85 years with a smoking history of more than 20 pack years, showing little or no improvement in FEV1 upon a bronchial challenge of 200 microg of inhaled salbutamol and exhibiting ABG percentage of less than 85% of oxygen saturation were taken up for the study. The study had 3 arms viz., the plant-based formulation (DCBT1234-Lung KR), placebo and salbutamol (12 mg/day) plus theophylline (300 mg/day) plus bromhexine (24 mg/day). The end point of the study was determined as an improvement of FEV1 by 200 mL and/or increased ABG values (>90% PaO2) and clinical symptoms like dyspnoea, wheezing, cough, expectoration, disability, and sleep disturbances. RESULTS: DCBT1234-Lung KR patients showed statistically significant (95% level) improvement in FEV1 and PaO2 in comparison with salbutamol+theophylline+bromhexine and placebo patients. Twenty-three per cent of DCBT1234-Lung KR patients, 19% of salbutamol+theophylline+bromhexine group and 12% of placebo group patients showed the desired 200 mL improvement in FEV1 values in comparison with the other 2 arms. Improved PaO2 was observed in 15.4% of the DCBT1234-Lung KR patients while no improvement was seen with patients in any other arms. Symptoms like dyspnoea, wheezing, cough, expectoration, disability and sleep disturbances also significantly reduced in DCBT1234-Lung KR and the biomedical group patients, but not in the placebo arm. CONCLUSIONS: DCBT1234-Lung KR was equivalent, if not better than the present day treatment with salbutamol, theophylline and bromhexine combination in COPD patients and this was ascertained using FEV1 and ABG values. (+info)No effect of a homoeopathic combination of Arnica montana and Bryonia alba on bleeding, inflammation, and ischaemia after aortic valve surgery. (3/4)
(+info)Cucurbitane-type triterpenes with anti-proliferative effects on U937 cells from an egyptian natural medicine, Bryonia cretica: structures of new triterpene glycosides, bryoniaosides A and B. (4/4)
The 90% aqueous ethanol extract of an Egyptian natural medicine, the roots of Bryonia cretica L., was found to exhibit a strong inhibitory effect on the proliferation of human leukemia U937 cells. By bioassay-guided fractionation, we isolated two new cucurbitane-type triterpene glycosides, bryoniaosides A and B, were isolated from the roots of Bryonia cretica L. together with 16 known cucurbitane-type triterpenes and glycosides. The chemical structures of bryoniaosides A and B were determined on the basis of chemical and spectroscopic evidence. Effects of principal cucurbitane-type triterpenes (cucurbitacins B, D, E, and J, 23,24-dihydrocucurbitacins B and E, and hexanorcucurbitacin D) on proliferation of the cells were examined. Cucurbitacins B and E showed the greater cytotoxic effects with IC(50) values of 9.2 and 16 nM after 72 h, and their IC(50) values were equivalent to that of camptothecin. An alpha,beta-conjugated ketone moiety at the 22-24-positions and an acetoxy group at the 25-position are essential for the strong activity. (+info)"Bryonia" is the medical term for a homeopathic remedy that is derived from the Bryonia alba or Bryonia dioica plants, which are types of wild vines also known as "white bryony" and "red bryony," respectively. The remedy is made from the plant's root, and it is used in homeopathic medicine to treat a variety of symptoms, particularly those that are worse with motion or touch and are accompanied by a desire for coolness and isolation. Some of the conditions that may be treated with Bryonia include respiratory illnesses, digestive disorders, and joint pain. It's important to note that homeopathic remedies are highly diluted and are not evaluated for safety or effectiveness by regulatory agencies such as the FDA.
Arnica (Arnica montana) is a plant that is native to the mountains of Europe and North America. It has been used in traditional medicine for centuries to treat various medical conditions, particularly those involving inflammation and pain. The flowers of the Arnica plant contain several active compounds, including sesquiterpene lactones, helenalin, and dihydrohelenalin, which are believed to be responsible for its medicinal properties.
Arnica is often applied topically as a cream, ointment, or salve to treat conditions such as bruises, sprains, muscle aches, and joint pain. It is thought to work by stimulating the flow of blood to the affected area, reducing inflammation, and promoting healing. Arnica may also have anti-inflammatory, antimicrobial, and analgesic effects.
However, it's important to note that Arnica can be toxic if taken internally in large doses or for extended periods of time. It should not be used on broken or damaged skin, and pregnant or breastfeeding women should avoid using it altogether. As with any medication or herbal remedy, it's always best to consult with a healthcare provider before using Arnica to ensure its safe and appropriate use.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
"Urtica dioica," also known as stinging nettle, is a plant species native to Europe, Asia, North Africa, and North America. While it doesn't have a formal medical definition, it is widely used in herbal medicine. The leaves and stems of the plant contain various compounds, including histamine, acetylcholine, serotonin, and forms of nitrogen like formic acid, which can cause a stinging sensation when they come into contact with human skin.
In medical contexts, Urtica dioica extracts are sometimes used to treat conditions such as allergies, joint pain, and urinary tract infections. However, it's important to note that the scientific evidence supporting these uses is generally limited, and more research is needed to confirm their effectiveness and safety. As with any medical treatment or supplement, individuals should consult with a healthcare provider before using Urtica dioica for therapeutic purposes.
I believe there may be some confusion in your question. "Moths" are not a medical term, but rather they are a group of insects closely related to butterflies. They belong to the order Lepidoptera and are characterized by their scales covering their wings and body. If you have any questions about moths or if you meant to ask something else, please let me know!
Naval medicine, also known as marine medicine or maritime medicine, is a branch of medicine that deals with the prevention and treatment of diseases and injuries that occur in naval or maritime environments. This can include conditions related to sea travel, such as motion sickness, decompression sickness, and infectious diseases spread through contaminated water or food. It also covers occupational health concerns for naval personnel, including hearing loss from exposure to loud noises, respiratory problems from inhaling fumes, and musculoskeletal injuries from heavy lifting. Additionally, naval medicine may address the unique mental health challenges faced by naval personnel, such as those related to isolation, stress, and combat.
"Butterflies" is not a medical term, but rather a colloquial or informal term that is often used to describe a feeling of nervousness or excitement in the stomach. It is thought to be due to the release of adrenaline and the increased heart rate and breathing that can occur when someone is anxious or excited. The sensation may be caused by the contraction of the muscles in the stomach, which can feel like fluttering or flips. This feeling is not a medical condition and does not typically require treatment, but if it is severe or persistent, it may be helpful to speak with a healthcare provider to address any underlying anxiety or stress.