Caplan Syndrome
Serum protein fractions in rheumatoid pneumoconiosis without arthritis. (1/4)
Fractionation of the serum proteins by filter-paper electrophoresis in 14 coal-miners who had the characteristic radiological opacities of rheumatoid pneumoconiosis but no evidence of rheumatoid arthritis showed a reduction in the mean level of albumin and increases in the alpha-2 and gamma-globulins compared with the values in non-arthritic miners with simple coal-workers' pneumoconiosis and in normal subjects. The changes were smaller than those found in miners with both rheumatoid arthritis and the radiological appearances of rheumatoid pneumoconiosis (Caplan's syndrome) and the mean levels did not differ significantly from those found in non-arthritic miners with progressive massive fibrosis. It is concluded that estimation of the serum protein fractions, unlike tests for rheumatoid factors, is unlikely to help in the differential diagnosis of unusual opacities seen on chest radiographs of miners without arthritis. (+info)Rheumatoid pneumoconiosis (Caplan's syndrome) with a classical presentation. (2/4)
(+info)Pulmonary manifestations of collagen diseases. (3/4)
(+info)Pulmonary function in coal workers with Caplan's syndrome and non-rheumatoid complicated pneumosoniosis. (4/4)
This retrospective study compares the pulmonary function of 24 coal workers with Caplan's syndrome with that of 36 subjects with non-rheumatoid progressive massive fibrosis (PMF). Allowing for differences in radiographical category, age, years worked underground, and smoking, obstruction to air flow as reflected in the one-second forced expiratory volume, the vital capacity, and the ratio of residual volume to total lung capacity, was significantly less in subjects with Caplan's syndrome. No significant differences in transfer factor were found. These findings may be explained by the different pathological features of the two entities. Selection bias does not appear to be responsible for the differences observed between the groups, but studies designed to eliminate this would be desirable. (+info)Caplan syndrome, also known as Caplan's syndrome or pneumoconiosis with rheumatoid nodules, is a rare condition characterized by the presence of multiple round, well-circumscribed nodules in the lungs. These nodules are similar to those seen in rheumatoid arthritis and are typically found in individuals who have been exposed to coal dust or other types of mineral dust.
The syndrome was first described in 1953 by Dr. Anthony Caplan, a Welsh physician who observed the association between pneumoconiosis (a lung disease caused by inhaling mineral dust) and rheumatoid nodules in coal miners. The condition is most commonly seen in coal miners, but it has also been reported in other occupations with exposure to mineral dust, such as stone cutters and sandblasters.
Caplan syndrome is thought to occur when the immune system's response to mineral dust exposure triggers an inflammatory reaction that leads to the formation of rheumatoid nodules in the lungs. The presence of these nodules can cause symptoms such as cough, shortness of breath, and chest pain. In severe cases, Caplan syndrome can lead to lung scarring and decreased lung function.
Diagnosis of Caplan syndrome typically involves a combination of medical history, physical examination, imaging studies (such as chest X-rays or CT scans), and laboratory tests (such as blood tests for rheumatoid arthritis). Treatment may include medications to manage the symptoms of rheumatoid arthritis and reduce inflammation in the lungs. In some cases, surgery may be necessary to remove severely damaged lung tissue.
A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.
For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.
It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.
Caplan's syndrome
HLA-A1
Rheumatoid arthritis
Black lung disease
Pneumoconiosis
Rheumatoid nodule
XYY syndrome
Felty's syndrome
False Memory Syndrome Foundation
Caplan (disambiguation)
Alien hand syndrome
Da Costa's syndrome
Parental alienation syndrome
Cerebellar stroke syndrome
Post viral cerebellar ataxia
Syndrome of inappropriate antidiuretic hormone secretion
Occupational lung disease
Posterior reversible encephalopathy syndrome
List of diseases (C)
List of MeSH codes (C08)
Rheumatoid lung disease
List of MeSH codes (C17)
List of MeSH codes (C21)
List of diagnoses characterized as pseudoscience
Dissociative identity disorder
List of syndromes
Nonverbal learning disorder
Louis R. Caplan
List of MeSH codes (C05)
Amygdalohippocampectomy
Caplan's syndrome - Wikipedia
Caplan syndrome | Multimedia Encyclopedia | Health Information | St. Luke's Hospital
Rheumatoid pneumoconiosis: MedlinePlus Medical Encyclopedia
Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) Medication: Corticosteroids, Pulmonary, Tyrosine...
Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD): Background, Pathophysiology, Epidemiology
Rheumatoid Arthritis: Common Questions About Diagnosis and Management | AAFP
Colinet-Caplan Syndrome: History of an Outbreak of Autoimmune Disease in Scouring Powder Workers. | Ann Intern Med;176(2): 260...
urofacial syndrome - Ontology Browser - Rat Genome Database
Paul Blanc, MD, MSPH | Center for Tobacco Control Research and Education
Frontiers | The Relation Between College Students' Social Anxiety and Mobile Phone Addiction: The Mediating Role of Regulatory...
Medial lenticulostriate arteries | Radiology Reference Article | Radiopaedia.org
Caplan, Jason P | Creighton University
Legit Internal Hacks | Wallhack, Skin Changer, RageBot - Spinnerstown Hotel
Homeopathic Remedies for Rheumatism - Robert Medhurst
Viral Bronchitis: Treatment, Causes, Symptoms, Investigations
Guideline for the management of patients with acute coronary syndromes without persistent ECG ST segment elevation | Heart
Byssinosis: Treatment, Causes, Symptoms, Signs, Prognosis
March 23-Take Action All In One Place - Take Action Canada
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
DeCS 2009 - Changed terms
Anthony Caplan2
- The syndrome is named after Dr. Anthony Caplan, a physician on the Cardiff Pneumoconiosis Panel, who identified the constellation of findings as a distinct entity in a 1953 publication. (wikipedia.org)
- The first modern description linking rheumatoid arthritis to occupational dust exposure is generally attributed to the British physician Anthony Caplan. (bvsalud.org)
Caplan's2
- Caplan's syndrome (or Caplan disease or rheumatoid pneumoconiosis) is a combination of rheumatoid arthritis (RA) and pneumoconiosis that manifests as intrapulmonary nodules, which appear homogeneous and well-defined on chest X-ray. (wikipedia.org)
- 8 arthritis, juvenile rheumatoid/ 9 caplan's syndrome.tw. (arthritisdaily.net)
Diagnosis2
Rheumatoid pneumoconiosis1
- Rheumatoid pneumoconiosis (RP, also known as Caplan syndrome) is swelling (inflammation) and scarring of the lungs. (medlineplus.gov)
19532
- Caplan, Anthony (1953). (wikipedia.org)
- In 1953, Caplan reported on a "peculiar" nodular pattern on chest radiographs of Welsh coal miners with rheumatoid arthritis that differed from the typical coal workers ' pneumoconiosis . (bvsalud.org)
Symptoms6
- Call for an appointment with your provider if you have symptoms of Caplan syndrome. (stlukes-stl.com)
- Approaches to psychiatric symptoms in Parkinson plus syndromes. (creighton.edu)
- Patients with a suspected acute coronary syndrome should be observed, with repeat 12 lead ECG recording, during symptoms if the opportunity arises. (bmj.com)
- This group was evaluated for the risk factors, presenting symptoms, killip class, type of acute coronary syndrome (STEMI vs NSTEMI), time to presentation to hospital, treatment received (medical management/thrombolysis/PCI/CABG), cardiac arrhythmias, mean ejection fraction, HRCT chest (CORADS grading), any complications and immediate outcome. (scialert.net)
- 8 Proven Sjogren's Syndrome Natural Treatments If you are one of the millions of people living with Sjogren's syndrome, you know how challenging it can be to manage the symptoms. (caplanhealthinstitute.com)
- Finding Catatonia Requires Knowing What to Look for Unlike common psychiatric syndromes, such as major depression, that are characterized by self-report of symptoms, catatonia is identified chiefly by empirically evaluated signs on clinical evaluation. (medscape.com)
Nodular1
- Caplan syndrome is a nodular condition of the lung occurring in dust-exposed persons with either a history of rheumatoid arthritis (RA) or who subsequently develop RA within the following 5-10 years. (wikipedia.org)
Acute8
- Patients with a confirmed acute coronary syndrome should be admitted to a cardiac care unit or high dependency unit with continuous ECG rhythm monitoring. (bmj.com)
- Confirmed acute coronary syndrome. (bmj.com)
- Patients who have had ischaemic ECG changes, or cardiac troponin release or raised CK-MB enzyme demonstrated at any time during admission, have a confirmed acute coronary syndrome. (bmj.com)
- However, it resulted in decreased hospitalization for acute coronary syndrome, delayed presentation and change in decision making. (scialert.net)
- In this study, done at tertiary care centre, patients of acute coronary syndrome over last 4 months underwent RT-PCR for SARS-CoV-2 and HRCT chest prior to admission. (scialert.net)
- A total of 25 (5.8%) patients with acute coronary syndrome who had evidence of COVID-19 infection were enrolled in the study. (scialert.net)
- In this study, 5.8% patients of acute coronary syndrome had evidence of COVID-19 infection. (scialert.net)
- More severe presentations include pneumonia and acute respiratory distress syndrome. (scialert.net)
Psychiatric3
- Caplan JP, Stoner SC, Livezey S. Case studies and conundrums: practical management of tardive dyskinesia for neurologic and psychiatric pharmacists. (creighton.edu)
- Caplan JP, Heinrich T, Lee HB, Sharpe M, Wulsin L. Debate: Resolved: proactive psychiatric consultation should be the standard of practice for inpatient psychiatric consultation services in general hospitals. (creighton.edu)
- Should "premenstrual syndrome" be called a psychiatric abnormality? (bvsalud.org)
Patients6
- Caplan syndrome occurs only in patients with both RA and pneumoconiosis related to mining dust (coal, asbestos, silica). (wikipedia.org)
- Because Colinet never clearly described the specific occupational context of his cases, Caplan syndrome has been misconstrued as uniquely a disease of coal miners .We attempted to reconstruct the working conditions of Colinet's patients and found that they were packing Vim, a silica -based scouring powder , at the Savonneries Lever Frères factory in Brussels, Belgium . (bvsalud.org)
- Immunoassay Detects Salivary Anti-SSA/Ro-52 Autoantibodies in Seronegative Patients with Primary Sjögren's Syndrome. (harvard.edu)
- Chronic pain syndrome and pain disorder are diagnostic labels frequently applied to patients who are thought to be demonstrating delayed recovery as a consequence of social reinforcement. (bcmj.org)
- Among them, three patients had Lateral Medullary Syndrome (LMS) with Ondine's curse. (biomedres.info)
- Brain diffusion-weighted imaging of lateral medullary syndrome with Ondine's curse of three patients. (biomedres.info)
Sjogren's Syndrome3
- Sjogren's Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
- This graph shows the total number of publications written about "Sjogren's Syndrome" by people in Harvard Catalyst Profiles by year, and whether "Sjogren's Syndrome" was a major or minor topic of these publication. (harvard.edu)
- Below are the most recent publications written about "Sjogren's Syndrome" by people in Profiles. (harvard.edu)
Cough1
- Caplan syndrome presents with cough and shortness of breath in conjunction with features of rheumatoid arthritis, such as painful joints and morning stiffness. (wikipedia.org)
Respiratory2
- Ondine's curse, also known as Central Alveolar Hypoventilation (CAH) syndrome is a rare clinical condition characterized by the loss of automatic respiratory drive, mostly during sleep but also during wakefulness. (biomedres.info)
- A 'Small Airway Disease Syndrome' provides a mechanism for respiratory disease following WTC dust exposure even in subjects with normal screening spirometry. (cdc.gov)
Progressive massive1
- Caplan syndrome was originally described in coal miners with progressive massive fibrosis. (wikipedia.org)
Lungs1
- Caplan syndrome is swelling (inflammation) and scarring of the lungs. (stlukes-stl.com)
Coal miners1
- Caplan syndrome is a rare disorder, but can attack coal miners suffering from rheumatic arthritis. (healthbeautyidea.com)
Dust3
- Caplan syndrome is caused by breathing in coal mining dust. (stlukes-stl.com)
- Minimal lung inflammation is normally seen in the inhalation fevers (e.g., organic dust toxic syndrome, metal fume fever and polymer fume fever ). (symptoma.com)
- ODTS is also called Toxic Organic Dust Syndrome (TODS), grain fever , or pulmonary mycotoxicosis. (symptoma.com)
Lupus-like syndrome1
- Cordrey EO, Benford DM, Caplan JP: Altered mental status due to golimumab: a case of TNF-alpha inhibitor induced lupus-like syndrome. (creighton.edu)
20011
- It can be observed from the relevant literature (see the review of random and controlled trials by O'Connor and Olson, 2001:271-290) that the literature on Fetal Alcohol Syndrome actually branches into the FAS developing as a consequence of prenatal exposure for the infant as well as the post natal attitude of the alcoholic mother to the child contributing to the effects of the FAS. (writemyessay.co.uk)
Felty's1
- 10 felty's syndrome.tw. (arthritisdaily.net)
Disorder3
- There is little merit to employing certain diagnostic labels such as chronic pain syndrome or pain disorder to explain persistence of pain and disability behaviors. (bcmj.org)
- One notable condition found in Pfizer's data is 1p36 deletion syndrome, which the National Library of Medicine describes as "a disorder that typically causes severe intellectual disability. (bigleaguepolitics.com)
- Childhood disintegrative (or disintegration) disorder, also known as Heller syndrome, and now subsumed under the Autism Spectrum Disorders (ASDs) category in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM5), is characterized by a loss of previously acquired language and social skills and results in a persistent delay in these areas. (medscape.com)
Idiopathic1
- Unclassifiable ILDs, autoimmune ILDs, chronic hypersensitivity pneumonitis, sarcoidosis, myositis, Sjögren syndrome, coal worker pneumoconiosis, and idiopathic forms of interstitial pneumonias (eg, idiopathic nonspecific interstitial pneumonia [NSIP]) are among the diseases that may develop a progressive form of chronic fibrosing ILD. (medscape.com)
Clinical3
- To analyse the clinical characteristic of Lateral Medullary Syndrome (LMS) with Ondine's curse. (biomedres.info)
- S2 Episode 4: Schizophrenia, Clinical High-risk Syndrome, and Psychosis Drs John M. Kane and Scott W. Woods discuss clinical high-risk syndrome and schizophrenia, including assessment methods, interventions, and risk indicators for future psychosis. (medscape.com)
- Ciguatera fish poisoning is a clinical syndrome caused by eating contaminated fish ( 1 ). (cdc.gov)
Disease3
- There is no specific treatment for Caplan syndrome, other than treating any lung and joint disease. (stlukes-stl.com)
- Colinet-Caplan Syndrome: History of an Outbreak of Autoimmune Disease in Scouring Powder Workers. (bvsalud.org)
- It is possible to track not the whole disease progress but only the part of it, but more thoroughly, for example the joint syndrome. (visualrheumatology.ru)
Diseases1
- A handout on this topic is available at http://familydoctor.org/familydoctor/en/diseases-conditions/rheumatoid-arthritis.html . (aafp.org)
Exposure1
- Exposure to environmental air pollutants as a risk factor for primary Sjögren's syndrome. (harvard.edu)
Lung1
- Caplan syndrome rarely causes serious breathing trouble or disability due to lung problems. (stlukes-stl.com)
Chronic2
- Many chronic whiplash cases are consistent with the key features of chronic pain syndromes and pain disorders, and thus constitute psychosocioeconomic problems. (bcmj.org)
- The chronic pain syndrome construct was delineated in 1987 when it was argued that chronic pain syndrome, as opposed to chronic pain, "has the added component of certain recognizable psychological and socioeconomic influences. (bcmj.org)
Epidemiology1
- Post-COVID-19 syndrome: epidemiology, diagnostic criteria and pathogenic mechanisms involved. (nih.gov)
Autoantibodies1
- [ 1 ] Many experts include the antineutrophil cytoplasmic autoantibody (ANCA)-related vasculitides and Goodpasture syndrome in this group because of the presence of autoantibodies. (medscape.com)
Condition1
- Although this condition initially was called Colinet- Caplan syndrome in the Francophone biomedical literature , Colinet's name was later dropped from the eponym . (bvsalud.org)
Rare1
- Caplan syndrome is very rare in the United States. (stlukes-stl.com)
Specific1
- For specific medical diagnoses and uncertainties, consult a specialist like Dr. Caplan at the CED Clinic to ensure safe and tailored care. (caplancannabis.com)
People1
- It's Wise to Hospitalize Mentally Ill Homeless People: Ethicist Arthur L. Caplan, PhD, discusses a movement to identify and treat severely mentally ill homeless individuals. (medscape.com)
Institute1
- Southwest Patient and Medical Professional Education Day - Focus on Parkinson Plus Syndromes, Barrow Neurological Institute, Phoenix, Arizona. (creighton.edu)
Form1
- The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. (harvard.edu)
Term1
- Jones and Smith (1973) were the first in medical academia to refer to use the term FAS (fetal alcohol syndrome), which collectively referred to mental and physical impairments of the fetus in later life after being pre-natally exposed to alcohol. (writemyessay.co.uk)
Medical1
- I'm Art Caplan, head of medical ethics at the New York University School of Medicine. (medscape.com)