Cephalotaxus
Harringtonines
Sequence Inversion
A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana. (1/8)
A novel C-methylated biflavone, taiwanhomoflavone-B (1), together with known compounds, 7,4',7"-tri-O-methylamentoflavone, 6-C-methylnaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of 1 was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively. (+info)Investigation of the essential oils from three Cephalotaxus species. (2/8)
Essential oils from leaves of Cephalotaxus fortunei Hook., Cephalotaxus haningtonia K. Koch., Cephalotaxus sinensis Li. and variety Cephalotaxus harringtonia var. drupacea Koidz. underwent qualitative and quantitative analysis. The content of the oils obtained by hydrodistillation in the investigated species was 0.01 - 0.22% v/w. Gas chromatography (GC-MS) with flame ionisation detector (FID) showed generally 47 components in the essential oils. In all investigated species the presence of a-pinene varying from 18.4% to 35.1%, as well as sesquiterpene hydrocarbon beta-caryophyllene up to 22% at Cephalotaxus fortunei were revealed as the main components. (+info)Antihyperglycemic effect of Cephalotaxus sinensis leaves and GLUT-4 translocation facilitating activity of its flavonoid constituents. (3/8)
The objectives of this study were to investigate the antihyperglycemic effect of Cephalotaxus sinensis leaves and to identify the active components. The antihyperglycemic effect of various fractions (FA, FB, FC, FD) of the 80% ethanol extract of the leaves was evaluated in streptozotocin (STZ)-induced diabetic rats. Among the tested fractions, FC was the most active. FC (0.48 g/kg) given orally for 10 d reduced significantly (p<0.001) the blood glucose of STZ-induced diabetic rats. The food and water intakes of FC (0.48 g/kg)-treated diabetic rats were reduced significantly (p<0.001) when compared to the 0.5% carboxymethyl cellulose (CMC)-treated diabetic rats. The activity-guided fractionation of the ethanol extract of C. sinensis leaves furnished three flavonoid compounds, apigenin-5-O-[alpha-L-rhamnopyranosyl-(1-->4)-6-O-beta-D-acetylglucopyranoside] (1), apigenin (2), and apigenin-5-O-[alpha-L-rhamnopyranosyl-(1-->4)-6-O-beta-D-glucopyranoside] (3). The elevation of GLUT-4 protein level in membrane preparations from mice adipocytes was detected by Western blot analysis after adipocytes were pre-incubated with FC (0.1, 1, 10 mg/ml), apigenin (0.1, 2 mg/ml) and apigenin-5-O-[alpha-L-rhamnopyranosyl-(1-->4)-6-O-beta-D-acetylglucopyranoside] (0.1, 2 mg/ml), respectively. Phytochemical investigation and HPLC-DAD analysis of FC indicated that the flavonoids were the major constituents in this fraction. These results suggest that the fraction from C. sinensis leaves is a promising drug for the treatment of diabetes, and that the flavonoids from this plant are the active constituents. (+info)Actinopolymorpha cephalotaxi sp. nov., a novel actinomycete isolated from rhizosphere soil of the plant Cephalotaxus fortunei. (4/8)
(+info)Development of microsatellite loci for Cephalotaxus oliveri (Cephalotaxaceae) and cross-amplification in Cephalotaxus. (5/8)
(+info)Antioxidant, antibacterial, cytotoxic, and apoptotic activity of stem bark extracts of Cephalotaxus griffithii Hook. f. (6/8)
(+info)Chemical communication between the endophytic fungus Paraconiothyrium variabile and the phytopathogen Fusarium oxysporum. (7/8)
(+info)The complete chloroplast genome sequence of Cephalotaxus oliveri (Cephalotaxaceae): evolutionary comparison of cephalotaxus chloroplast DNAs and insights into the loss of inverted repeat copies in gymnosperms. (8/8)
(+info)"Cephalotaxus" is a genus of evergreen coniferous trees and shrubs, also known as "plum yews." They belong to the family Cephalotaxaceae. These plants are native to eastern Asia, particularly in regions of China, Japan, and Korea.
The bark, leaves, and seeds of some Cephalotaxus species have been used in traditional medicine for various purposes. For instance, an alkaloid extract from the bark and leaves, called "harringtonine," has shown anticancer properties and is being investigated as a potential cancer treatment. However, it's important to note that using these plants or their extracts for medicinal purposes should only be done under the guidance of a healthcare professional, as they can have toxic effects if not used properly.
Harringtonines are a group of alkaloids isolated from the plant *Cephalotaxus harringtonia* (also known as Platycladus orientalis), which has been used in traditional Chinese medicine. These compounds have been found to exhibit antitumor and anti-leukemic activities, and they are believed to work by inhibiting the formation of microtubules, which are critical for cell division.
Specifically, harringtonines bind to tubulin, a protein that makes up microtubules, and prevent it from forming stable structures. This leads to disruption of the mitotic spindle, which is necessary for chromosome separation during cell division. As a result, cells are unable to divide properly and undergo apoptosis (programmed cell death).
Harringtonines have been studied in clinical trials as potential cancer treatments, but their use is limited due to their narrow therapeutic index and significant side effects, including neurotoxicity and myelosuppression. Further research is needed to develop more targeted and less toxic therapies based on these compounds.
'Sequence inversion' is not a commonly used term in medicine, but it can be found in the context of genetics and genomics. It refers to a type of genetic variation where a segment of DNA is reversed end-to-end, resulting in a sequence that is identical to the original but in reverse order. This type of rearrangement can have various consequences, depending on its location and the function of the genes involved. In some cases, it may lead to changes in gene expression or protein structure, which could potentially contribute to the development of genetic disorders or other health conditions. However, it is important to note that not all sequence inversions have pathological consequences, as many can occur without any noticeable effects on an individual's health.
Flame Ionization is not a medical term, but rather a scientific technique used in analytical chemistry to detect and measure the presence of certain organic compounds. It is based on the principle that when an organic compound is introduced into a flame, it breaks down into ions and electrons, creating an electrical current that can be measured. This technique is often used in gas chromatography to identify and quantify volatile organic compounds (VOCs) in biological samples such as breath, blood, or urine. However, it is not typically used as a diagnostic tool in medicine.
Cephalotaxus
Cephalotaxus oliveri
Cephalotaxus koreana
Cephalotaxus wilsoniana
Cephalotaxus hainanensis
Cephalotaxus mannii
Cephalotaxus alkaloids
Cephalotaxus latifolia
Cephalotaxus griffithii
Cephalotaxus lanceolata
Cephalotaxus sinensis
Cephalotaxus harringtonii
Cephalotaxus fortunei
List of near threatened plants
Yew
List of least concern plants
Wojsławice Arboretum
List of endangered plants
Paleobiota of the London Clay
Catechin-7-O-glucoside
Hainan
Pliocene flora of Frankfurt am Main
Omacetaxine mepesuccinate
Nakai-Nam Theun National Park
Actinopolymorpha
Yangmingshan National Forest Park
Flora of Japan
List of the Cenozoic life of Washington
Glen Saint Mary Nurseries Company
Taxaceae
Cephalotaxus - Wikipedia
Cephalotaxus harringtonia, Japanese Plum Yew, Harrington's Cephalotaxus, Cowtail Pine
Japanese Plum Yew (Cephalotaxus harringtonia 'Prostrata')
I Love Cephalotaxus harringtonia 'Fastigiata' aka upright Japanese Plum Yew | GardenLady.com
Effects of Different Treatments on Physiological Characteristics of Cephalotaxus sinensis Seeds
Cephalotaxus sinensis - Wikipedia
Cephalotaxus Archives - Moon Nurseries
Søjleblommetaks - Cephalotaxus harringtonia Fastigiata
Cephalotaxus harringtonia 'Fastigiata' (Japanese Plum Yew)
Cephalotaxus harringtonia 'Korean Gold' - Outdoor Design & Living Store
Spreading Japanese Plum Yew | Cephalotaxus h. 'Prostrata' - Revolutionary Gardens
Duke Gardens Japanese Plum Yew - Cephalotaxus harringtonia 'Duke Gardens' - ServeScape
Cephalotaxus harringtonia Duke Gardens Plum Yew from Pleasant Run Nursery
Cephalotaxus ha. 'Duke Gardens' C3.5 25-30 - Van der Hoek Boomkwekerij
Family: Cephalotaxaceae - Genus: Cephalotaxus - Taxon: koreana (High Resolution image - Identification Key)
Csonth jas ltiszafa (Cephalotaxus harringtonia var. drupacea) gondoz sa, szapor t sa
Prostrate Japanese Plum Yew (Cephalotaxus harringtonia 'Prostrata') in Oklahoma City Edmond Norman Moore Oklahoma OK at TLC...
Ekkehard Winterfeldt (1932 - 2014) - ChemistryViews
Search Use
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Image Search | Arnold Arboretum...
JYX - Synthetic studies on 1-azabicyclo[5.3.0]decane alkaloids (full record)
Nageia - Wikipedia, frjálsa alfræðiritið
Sheffield's Seed Company
Sheffield's Seed Company
Harringtonines | Semantic Scholar
Taylor's Nursery
Harringtonia6
- Cephalotaxus harringtonia 'Fastigiata' is an upright columnar form. (toptropicals.com)
- Why do I love spreading Japanese plum yew ( Cephalotaxus harringtonia 'Prostrata' )? (revolutionarygardens.com)
- Cephalotaxus harringtonia 'Duke Gardens' has dark evergreen foliage and a tight, compact form. (pleasantrunnursery.com)
- Csonth jas ltiszafa (Cephalotaxus harringtonia var. (botanikaland.hu)
- A new Cephalotaxus alkaloid, cephastigiamide A ( 1 ), has been isolated from the leaves of Cephalotaxus harringtonia forma fastigiata and the structure was elucidated by 2D NMR analysis and chemical degradation. (heterocycles.jp)
- The Yucca recurvifolia (Curve Leaf Yucca) blooming next to the Waterwise Deck is magnificent in full bloom next to a yellow-foliaged Cephalotaxus harringtonia cv. (arboretumfriends.org)
Plum yew2
- Cephalotaxus, commonly called plum yew or cowtail pine, is a genus of conifers comprising 11 species, either considered the only member of the family Cephalotaxaceae, or in the Taxaceae when that family is considered in a broad sense. (wikipedia.org)
- Baisha is home to precious animals and plants including the Cephalotaxus hainanensis Li or Hainan plum-yew, Hainan Eld's deer and Hainan black-crested gibbons. (cgtn.com)
Cephalotaxaceae1
- An Cephalotaxus sinensis in nahilalakip ha genus nga Cephalotaxus , ngan familia nga Cephalotaxaceae . (wikipedia.org)
Alkaloids1
- Structure-activity relationship for antiplasmodial activity of isolated Cephalotaxus alkaloids was also discussed. (heterocycles.jp)
Sinensis seeds1
- Cephalotaxus sinensis seeds can't germinate even in the appropriate environment. (scirp.org)
Duke Gardens1
- They planted Distytlium 'Vintage Jade' and Cephalotaxus 'Duke Gardens. (burlingtonnc.gov)
Seeds2
- To investigate the effect of cold stratification and different concentrations of exogenous GA 3 on dormancy breaking in seeds of Cephalotaxus sinensis, we monitored germination rates and changes in soluble sugar, starch, amylase, soluble protein, free amino acid during cold stratification. (scirp.org)
- Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. (semanticscholar.org)
Cephalotaxine1
- Cephalotaxus species produce cephalotaxine, an alkaloid. (wikipedia.org)
Defined using character1
- The taxonomy of Cephalotaxus is difficult, because the species have been defined using characteristics that intergrade with each other, such as the length and shape of needles, bark, and stomatal band color. (wikipedia.org)
Species2
- Cephalotaxus species have often been separated geographically rather than morphologically. (wikipedia.org)
- An Cephalotaxus sinensis [2] in uska species han Plantae in nahilalakip ha punoan nga Tracheophyta , ngan nga syahan ginhulagway ni Alfred Rehder ngan Ernest Henry Wilson , ngan ginhatag han pagkayana nga asya nga ngaran ni Hui Lin Li . (wikipedia.org)
Date1
- The youngest fossils of Cephalotaxus in Europe date to the Pliocene, and remains are also known from the Miocene of western North America. (wikipedia.org)
Studies1
- Molecular studies place Cephalotaxus as the most basal member of the Taxaceae, having a very ancient divergence from them during the late Triassic. (wikipedia.org)
Fortunei1
- Inside the park there are grotesque rocks, dense forest, rare plants (e.g. gingko trees, cephalotaxus fortunei) and animals (e.g. macaque, musk deer, giant salamanders), crystal streams here and there, which are introduced to visitors because of the hot springs. (visitourchina.com)
Plum2
- Cephalotaxus, commonly called plum yew or cowtail pine, is a genus of conifers comprising 11 species, either considered the only member of the family Cephalotaxaceae, or in the Taxaceae when that family is considered in a broad sense. (wikipedia.org)
- 1 Fastigiate Japanese Plum Yew (Cephalotaxus h. (blogspot.com)
Arboretum1
- To see a collection of several different types of Cephalotaxus , visit the JC Raulston Arboretum at NC State (4415 Beryl Rd, Raleigh, NC 27606). (myattlandscaping.com)
Plant1
- Genetic Diversity of Cephalotaxus mannii, a Rare and Endangered Plant [J]. J Integr Plant Biol. (jipb.net)