Chronobiology Phenomena
Chronobiology Discipline
Chronotherapy
Efficacy of bright light and sleep/darkness scheduling in alleviating circadian maladaptation to night work. (1/96)
We tested the hypothesis that circadian adaptation to night work is best achieved by combining bright light during the night shift and scheduled sleep in darkness. Fifty-four subjects participated in a shift work simulation of 4 day and 3 night shifts followed by a 38-h constant routine (CR). Subjects received 2,500 lux (Bright Light) or 150 lux (Room Light) during night shifts and were scheduled to sleep (at home in darkened bedrooms) from 0800 to 1600 (Fixed Sleep) or ad libitum (Free Sleep). Dim light melatonin onset (DLMO) was measured before and after the night shifts. Both Fixed Sleep and Bright Light conditions significantly phase delayed DLMO. Treatments combined additively, with light leading to larger phase shifts. Free Sleep subjects who spontaneously adopted consistent sleep schedules adapted better than those who did not. Neither properly timed bright light nor fixed sleep schedules were consistently sufficient to shift the melatonin rhythm completely into the sleep episode. Scheduling of sleep/darkness should play a major role in prescriptions for overcoming shift work-related phase misalignment. (+info)beta(1)-adrenergic antagonists improve sleep and behavioural disturbances in a circadian disorder, Smith-Magenis syndrome. (2/96)
Smith-Magenis syndrome (SMS) is a clinically recognisable contiguous gene syndrome ascribed to interstitial deletions of chromosome 17p11.2. Patients have a phase shift of their circadian rhythm of melatonin with a paradoxical diurnal secretion of the hormone. Serum melatonin levels and day-night behaviour were studied in nine SMS children (aged 4 to 17 years) given acebutolol, a selective beta(1)-adrenergic antagonist (10 mg/kg early in the morning). Cardiac examination, serum melatonin, motor activity recordings, and sleep diaries were monitored before and after drug administration. The present study shows that a single morning dose of acebutolol suppressed the inappropriate secretion of melatonin in SMS. A significant improvement of inappropriate behaviour with increased concentration, delayed sleep onset, increased hours of sleep, and delayed waking were also noted. These results suggest that beta(1)-adrenergic antagonists help to manage hyperactivity, enhance cognitive performance, and reduce sleep disorders in SMS. (+info)Hypothalamic involvement in chronic migraine. (3/96)
OBJECTIVES: Chronic migraine (CM), previously called transformed migraine, is a frequent headache disorder that affects 2%-3% of the general population. Analgesic overuse, insomnia, depression, and anxiety are disorders that are often comorbid with CM. Hypothalamic dysfunction has been implicated in its pathogenesis, but it has never been studied in patients with CM. The aim was to analyze hypothalamic involvement in CM by measurement of melatonin, prolactin, growth hormone, and cortisol nocturnal secretion. METHODS: A total of 338 blood samples (13/patient) from 17 patients with CM and nine age and sex matched healthy volunteers were taken. Melatonin, prolactin, growth hormone, and cortisol concentrations were determined every hour for 12 hours. The presence of comorbid disorders was also evaluated. RESULTS: An abnormal pattern of hypothalamic hormonal secretion was found in CM. This included: (1) a decreased nocturnal prolactin peak, (2) increased cortisol concentrations, (3) a delayed nocturnal melatonin peak in patients with CM, and (4) lower melatonin concentrations in patients with CM with insomnia. Growth hormone secretion did not differ from controls. CONCLUSION: These results support hypothalamic involvement in CM, shown by a chronobiologic dysregulation, and a possible hyperdopaminergic state in patients with CM. Insomnia might be an important variable in the study findings. (+info)Heart rate and energy expenditure of incubating wandering albatrosses: basal levels, natural variation, and the effects of human disturbance. (4/96)
We studied the changes in heart rate (HR) associated with metabolic rate of incubating and resting adult wandering albatrosses (Diomedea exulans) on the Crozet Islands. Metabolic rates of resting albatrosses fitted with external HR recorders were measured in a metabolic chamber to calibrate the relationship between HR and oxygen consumption (V(O(2))) (V(O(2))=0.074 x HR+0.019, r(2)=0.567, P<0.001, where V(O(2)) is in ml kg(-1) min(-1) and HR is in beats min(-1)). Incubating albatrosses were then fitted with HR recorders to estimate energy expenditure of albatrosses within natural field conditions. We also examined the natural variation in HR and the effects of human disturbance on nesting birds by monitoring the changes in HR. Basal HR was positively related to the mass of the individual. The HR of incubating birds corresponded to a metabolic rate that was 1.5-fold (males) and 1.8-fold (females) lower than basal metabolic rate (BMR) measured in this and a previous study. The difference was probably attributable to birds being stressed while they were held in the metabolic chamber or wearing a mask. Thus, previous measurements of metabolic rate under basal conditions or for incubating wandering albatrosses are likely to be overestimates. Combining the relationship between HR and metabolic rate for both sexes, we estimate that wandering albatrosses expend 147 kJ kg(-1) day(-1) to incubate their eggs. In addition, the cost of incubation was assumed to vary because (i) HR was higher during the day than at night, and (ii) there was an effect of wind chill (<0 degrees C) on basal HR. The presence of humans in the vicinity of the nest or after a band control was shown to increase HR for extended periods (2-3 h), suggesting that energy expenditure was increased as a result of the disturbance. Lastly, males and females reacted differently to handling in terms of HR response: males reacted more strongly than females before handling, whereas females took longer to recover after being handled. (+info)Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. (5/96)
Mammalian free-running circadian rhythms are entrained to the external light/dark cycle by photic signaling to the suprachiasmatic nuclei via the retinohypothalamic tract (RHT). We investigated the circadian entrainment and clock properties of math5-/- mutant mice. math5 is a critical regulator of retinal ganglion cell development; math5-/- mice show severe optic nerve hypoplasia. By anterograde cholera toxin B tracing, we find that math5-/- mice do not develop an identifiable RHT pathway. This appears to be attributable to agenesis or dysgenesis of the majority of RHT-projecting retinal ganglion cells. math5-/- mice display free-running circadian rhythms with a period approximately 1 hr longer than B6/129 controls (24.43 +/- 0.10 vs 23.62 +/- 0.19 hr; p < 0.00001). The free-running period of heterozygote mice is indistinguishable from that of controls. math5-/- mice show no entrainment to light/dark cycles, whereas heterozygote mice show normal entrainment to both 12 hr light/dark cycles and to a 1 hr skeletal photoperiod. math5-/- mice show reduced ability to entrain their rhythms to the nonphotic time cue of restricted running wheel access but demonstrate both free-running behavior and entrained anticipation of wheel unlocking in these conditions, suggesting the presence of a second diurnal oscillatory system in math5-/- animals. These results demonstrate that retinal ganglion cell input is not necessary for the development of a free-running circadian timekeeping system in the suprachiasmatic nucleus but is important for both photic entrainment and determination of the free-running period. (+info)Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo. (6/96)
BACKGROUND: Decreased heart rate variability (HRV) and increased blood pressure variability (BPV), determined in part by nitric oxide (NO)-dependent endothelial dysfunction, are correlated with adverse prognosis in cardiovascular diseases. We examined potential alterations in BPV and HRV in genetically dyslipidemic, apolipoprotein (apo) E-/-, and control mice and the effect of chronic statin treatment on these parameters in relation to their NO synthase (NOS)-modifying properties. METHODS AND RESULTS: BP and HR were recorded in unrestrained, nonanesthetized mice with implanted telemetry devices with or without rosuvastatin. Cardiac and aortic expression of endothelial NOS and caveolin-1 were measured by immunoblotting. Both systolic BP and HR were elevated in apoE-/- mice, with abolition of their circadian cycles. Spectral analysis showed an increase in their systolic BPV in the very-low-frequency (+17%) band and a decrease in HRV in the high-frequency (-57%) band, reflecting neurohumoral and autonomic dysfunction. Decreased sensitivity to acute injection of atropine or an NOS inhibitor indicated basal alterations in both parasympathetic and NOS regulatory systems in apoE-/- mice. Aortic caveolin-1 protein, an inhibitor of endothelial NOS, was also increased in these mice by 2.0-fold and correlated positively with systolic BPV in the very-low-frequency band. Rosuvastatin treatment corrected the hemodynamic and caveolin-1 expression changes despite persisting elevated plasma cholesterol levels. CONCLUSIONS: Rosuvastatin decreases caveolin-1 expression and promotes NOS function in apoE-/-, dyslipidemic mice in vivo, with concurrent improvements in BPV and HRV. This highlights the beneficial effects of rosuvastatin on cardiovascular function beyond those attributed to lipid lowering. (+info)An abrupt shift in the day/night cycle causes desynchrony in the mammalian circadian center. (7/96)
The suprachiasmatic nucleus (SCN) is the neuroanatomical locus of the mammalian circadian pacemaker. Here we demonstrate that an abrupt shift in the light/dark (LD) cycle disrupts the synchronous oscillation of circadian components in the rat SCN. The phases of the RNA cycles of the period genes Per1 and Per2 and the cryptochrome gene Cry1 shifted rapidly in the ventrolateral, photoreceptive region of the SCN, but were relatively slow to shift in the dorsomedial region. During the period of desynchrony, the animals displayed increased nighttime rest, the timing of which was inversely correlated with the expression of Per1 mRNA in the dorsomedial SCN. Molecular resynchrony required approximately 6 d after a 10 hr delay and 9 approximately 13 d after a 6 hr advance of the LD cycle and was accompanied by the reemergence of normal rest-activity patterns. This dissociation and slow resynchronization of endogenous oscillators within the SCN after an LD cycle shift suggests a mechanism for the physiological symptoms that constitute jet lag. (+info)Loss of circadian rhythm of blood pressure following acute stroke. (8/96)
BACKGROUND: Epidemiology of acute stroke in developing countries differs from that in the developed world, for example, the age at stroke, risk factors, subtypes of stroke and prognosis. Hypertension remains a dominant risk factor and prognostic indicator in patients with stroke in all communities. The risk of stroke is directly related to elevations of blood pressure. A number of clinical studies have shown that the control of hypertension leads to a reduction in the incidence of stroke in a community. However there is still considerable controversy surrounds the changes in blood pressure in various subtypes of strokes and problem of management of elevated BP after stroke. We studied the circadian rhythm of blood pressure in patients following acute stroke. METHODS: To study the circadian rhythm of blood pressure, fifty consecutive patients with an acute stroke who were admitted to medical emergency within 120 hours of onset were included in the study. After a detailed history and clinical examination, a continuous blood pressure monitor (Spacelab 90207) was attached on the side ipsilateral to intracranial lesion (unaffected arm). The blood pressure was recorded for 24 hours at 15 minutes interval during daytime (6.00 am-6.00 pm) and 20 minutes interval overnight (6 pm to 6 am). RESULTS: Risk factors for stroke in 50 patients included hypertension in 31(62%), diabetes mellitus in 4 (8%), smoking in 13 (26%) and previous history of transient ischemic attack in 7 (14%) patients. Mean systolic pressure and diastolic pressure at admission were higher in patients with hemorrhagic stroke -29 patients (177 +/- 24 mmHg and 105 +/- 19 mmHg respectively) compared to patients with ischemic strokes-21 patients (150 +/- 36 mm Hg and 89 +/- 18 mm Hg respectively, p value <0.01 in both comparisons). The normal diurnal variation in blood pressure (night time dipping of more than 10%) was abolished in 44 (88%) of patients. Out of 44 nondippers, 29 patients showed reverse dipping i.e. rise of BP during night time compared to day time levels. None of the risk factors, clinical or laboratory variables, type of stroke or blood pressure changes differed significantly between these two groups. CONCLUSIONS: Therefore, we showed a pathologically reduced or abolished circadian BP variation after stroke. Absence of normal dipping results in a higher 24 hour blood pressure load and may have more target organ damage than those with normal diurnal variation of blood pressure. (+info)Chronobiology is the study of biological rhythms and their synchronization with environmental cycles. It examines how various biological processes in living organisms, including humans, are regulated by endogenous (internal) and exogenous (external) factors that recur over a specific time period. These rhythmic phenomena are known as circadian, ultradian, and infradian rhythms.
Circadian rhythms have a periodicity of approximately 24 hours and regulate many physiological processes such as sleep-wake cycles, body temperature, hormone secretion, and metabolism. Ultradian rhythms are shorter than 24 hours and include processes like heart rate variability, brain wave activity during sleep, and digestive enzyme release. Infradian rhythms have a longer periodicity, ranging from days to years, and include menstrual cycles in women and seasonal variations in animals.
Chronobiology phenomena are crucial for understanding the timing of various physiological processes and how they can be influenced by external factors like light-dark cycles, social cues, and lifestyle habits. This knowledge has applications in fields such as medicine, agriculture, and environmental science.
Chronobiology disorders are a group of conditions that involve disruptions in the body's internal biological clock, which regulates various physiological processes such as sleep-wake cycles, hormone release, and metabolism. These disorders can result in a variety of symptoms, including difficulty sleeping, changes in mood and energy levels, and problems with cognitive function.
Some common examples of chronobiology disorders include:
1. Delayed Sleep Phase Syndrome (DSPS): This condition is characterized by a persistent delay in the timing of sleep, so that an individual's preferred bedtime is significantly later than what is considered normal. As a result, they may have difficulty falling asleep and waking up at socially acceptable times.
2. Advanced Sleep Phase Syndrome (ASPS): In this condition, individuals experience an earlier-than-normal timing of sleep, so that they become sleepy and wake up several hours earlier than most people.
3. Non-24-Hour Sleep-Wake Rhythm Disorder: This disorder is characterized by a persistent mismatch between the individual's internal biological clock and the 24-hour day, resulting in irregular sleep-wake patterns that can vary from day to day.
4. Irregular Sleep-Wake Rhythm Disorder: In this condition, individuals experience a lack of consistent sleep-wake patterns, with multiple periods of sleep and wakefulness throughout the 24-hour day.
5. Shift Work Sleep Disorder: This disorder is caused by the disruption of normal sleep-wake patterns due to working irregular hours, such as night shifts or rotating schedules.
6. Jet Lag Disorder: This condition occurs when an individual travels across time zones and experiences a temporary mismatch between their internal biological clock and the new local time.
Treatment for chronobiology disorders may include lifestyle changes, such as adjusting sleep schedules and exposure to light, as well as medications that can help regulate sleep-wake cycles. In some cases, cognitive-behavioral therapy (CBT) may also be helpful in managing these conditions.
Chronobiology is the scientific discipline that studies the rhythmic patterns and cycles in living organisms (including humans) in relation to their environment, particularly in relation to the 24-hour day and longer seasonal cycles. It examines how various physiological processes and behaviors are synchronized with these external time cues, also known as zeitgebers.
Examples of areas studied within chronobiology include:
1. Circadian rhythms: These are the internal biological clocks that regulate many aspects of human physiology and behavior over a 24-hour period, such as sleep-wake cycles, body temperature, hormone release, and metabolism.
2. Seasonal affective disorder (SAD): This is a type of depression that occurs in response to changes in seasons, typically during the winter months when there is less natural light available.
3. Jet lag: This is a temporary disruption of circadian rhythms caused by rapid travel across time zones, resulting in symptoms such as fatigue, insomnia, and difficulty concentrating.
4. Shift work disorder: This is a condition that affects people who work irregular hours or night shifts, causing disturbances in sleep patterns and other physiological processes.
5. Menstrual cycle regulation: Chronobiology studies the hormonal changes and rhythms associated with the menstrual cycle to better understand reproductive health and potential treatments for related disorders.
Overall, chronobiology seeks to understand how these internal and external time cues interact and influence various aspects of human health and disease.
Chronotherapy is a medical treatment strategy that involves adjusting the timing of medication or other treatments based on the body's internal clock or circadian rhythms. The goal of chronotherapy is to optimize the effectiveness and minimize the side effects of treatments by administering them at specific times when they are most likely to be beneficial and well-tolerated.
For example, certain medications may be more effective when given at night because the body's metabolism slows down during sleep, allowing the drug to remain in the system longer. Similarly, some cancer treatments may be more effective when administered in the morning or evening based on the patient's circadian rhythms.
Chronotherapy can also involve adjusting lifestyle factors such as diet, exercise, and light exposure to help regulate the body's internal clock and improve overall health. This approach has been shown to be effective in treating a variety of conditions, including insomnia, depression, asthma, and cardiovascular disease.
A circadian rhythm is a roughly 24-hour biological cycle that regulates various physiological and behavioral processes in living organisms. It is driven by the body's internal clock, which is primarily located in the suprachiasmatic nucleus (SCN) of the hypothalamus in the brain.
The circadian rhythm controls many aspects of human physiology, including sleep-wake cycles, hormone secretion, body temperature, and metabolism. It helps to synchronize these processes with the external environment, particularly the day-night cycle caused by the rotation of the Earth.
Disruptions to the circadian rhythm can have negative effects on health, leading to conditions such as insomnia, sleep disorders, depression, bipolar disorder, and even increased risk of chronic diseases like cancer, diabetes, and cardiovascular disease. Factors that can disrupt the circadian rhythm include shift work, jet lag, irregular sleep schedules, and exposure to artificial light at night.
Sleep in bipolar disorder
Phase response curve
Diurnal mood variation
Seasonal affective disorder
Metabolic syndrome
Chronobiotic
Biology of bipolar disorder
Delayed sleep phase disorder
Advanced sleep phase disorder
Familial sleep traits
Non-24-hour sleep-wake disorder
Light effects on circadian rhythm
Entrainment (chronobiology)
Circadian rhythm
Irregular sleep-wake rhythm disorder
Computer vision syndrome
Suprachiasmatic nucleus
Circadian rhythm sleep disorder
List of cycles
Morningness-eveningness questionnaire
Depopulation of cockroaches in post-Soviet states
Sato Honma
Jürgen Aschoff
Lynne Lamberg
Night owl
Johanna Meijer
Jrk
Thomas Wehr
Melatonin
Shift work
Chronobiology Disorders | Profiles RNS
Sleep in bipolar disorder - Wikipedia
Scandinavian Journal of Work, Environment & Health - Does outdoor work during the winter season protect against depression and....
IJMS | Special Issue : Overcoming Brain Barriers
Seasonal Affective Disorder and the Power of Positive Self-Talk - iRunFar
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Individual differences in light sensitivity affect sleep and circadian rhythms
Molecular Vision: A standardized method to assess the endogenous activity and the light-response of the retinal clock in mammals
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Seasonal Depression (Seasonal Affective Disorder) Symptoms, Causes, Treatments
book - Centre for Chronobiology
Pediatric Sleep Disorders: Practice Essentials, Background, Pathophysiology
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Michael J. Thorpy - Publications - Albert Einstein College of Medicine
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BWH Press Release - Brigham and Women's Hospital
Medicine, Endocrinology Division - Research Output - Northwestern Scholars
Serena Roney-Dougal
Chronobiology: working at your own optimum | KONICA MINOLTA
Anette Harris | University of Bergen
DeCS - New terms
DeCS - Termos Novos
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DeCS - Términos Nuevos
Medical Chronobiology Program4
- 1 Medical Chronobiology Program, Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women's Hospital, Boston, MA. (nih.gov)
- We wanted to test the mechanisms that may explain why late eating increases obesity risk," explained senior author Frank A. J. L. Scheer, PhD, Director of the Medical Chronobiology Program in the Brigham's Division of Sleep and Circadian Disorders . (brighamandwomens.org)
- said first author Nina Vujovic, PhD, a researcher in the Medical Chronobiology Program in the Brigham's Division of Sleep and Circadian Disorders. (brighamandwomens.org)
- Frank Scheer is a senior author and the director of the Brigham's Division of Sleep and Circadian Disorders' Medical Chronobiology Program. (coherentmarketinsights.com)
Affective Disorders1
- Chronotherapeutics for Affective Disorders. (chronobiology.ch)
Depressive Disorder1
- Bipolar disorder and major depressive disorder are recurrent mood disorders which have a huge impact on a person's life and their ability to function. (newsroom.co.nz)
Insomnia3
- Alex and his guest, a leading music and media effect researcher and award winning music producer will discuss the science of rhythms in biological processes and the use of chronobiological music treatments than could contribute to the management of different disorders such as essential hypertension, insomnia and depression. (advancedbrain.com)
- How Does Insomnia Affect Depression and Anxiety in Patients With Insomnia Disorder? (chronobiologyinmedicine.org)
- Delayed sleep-wake phase disorder may disguise itself as insomnia, attention deficit disorder, emotional or affective disorder, or maladjustment, and it can be somewhat similar to the schedule seen in restless legs syndrome. (medlink.com)
Depression11
- If so, you might have seasonal depression , also known as seasonal affective disorder (SAD). (webmd.com)
- Seasonal depression is a mood disorder that happens every year at the same time. (webmd.com)
- It's not a separate mood disorder but a type of major depression or bipolar disorder , sometimes called manic depression . (webmd.com)
- The type of treatment you get also depends on whether you have another type of depression or bipolar disorder. (webmd.com)
- It brings about sleep problems, depression and cardiovascular disorders. (konicaminolta.eu)
- After 40 years at the frontline, the University of Otago's Professor Marie Crowe discusses her research on treatments beyond medicine to alleviate symptoms of mood disorders like bipolar and depression. (newsroom.co.nz)
- We initially used this psychotherapy for bipolar disorder but are now using it in studies of any recurrent depression and have found indications that in conjunction with medication it significantly improves the person's ability to function at home with family, at work, with friends and with social activities. (newsroom.co.nz)
- Low serotonin levels are associated with depression and seasonal affective disorder (SAD). (instantdaylite.com)
- Two years ago, the Chronobiology and Chronotherapy Task Force of the International Society of Bipolar Disorders reviewed all the clinical studies done on each type of chronotherapy to determine its effectiveness and tolerability in the acute and maintenance treatment of bipolar depression and mania. (cet.org)
- People can often suffer from more than one form of anxiety, and those with anxiety disorders often suffer from depression, eating disorders or substance abuse as well. (issuu.com)
- For this reason, we completed a pilot study in women with stable depression in the context of bipolar disorder. (medscape.com)
Neurological5
- Functional Neurological Disorder. (harvard.edu)
- Bi-allelic variants in INTS11 are associated with a complex neurological disorder. (harvard.edu)
- This problem has led to the emergence of novel strategies to treat neurological disorders, like the development of nanoformulations to deliver therapeutic agents to the brain. (bvsalud.org)
- The conjugation of nanoformulations with chronobiology for neurological disorders is still unexplored. (bvsalud.org)
- For respiratory indications, PSG is a standard indication for obstructive sleep apnea evaluation, following adenotonsillectomy for obstructive sleep apnea syndrome (OSAS), craniofacial anomalies that disrupt the upper airway, and neurological disorders (trisomy 21, Prader-Willi syndrome, and myelomeningocele). (medscape.com)
Michael Wieden2
- Generation Y expect a work environment that takes their individual needs into account,' explains Michael Wieden, author of Chronobiologie im Personalmanagement (Chronobiology in HR Management). (konicaminolta.eu)
- Innovation in shift planning - At the beginning there was a lecture by me (Michael Wieden) on the subject of"Chronobiology in personnel scheduling" and subsequently a joint workshop with managers from the Wartenberg Clinic. (chronocollege.de)
Disturbances4
- Other related sleep disturbances are delayed sleep phase syndrome, circadian-rhythm sleep disorder, sleep apnea, REM sleep abnormalities and irregular sleep-wake schedules. (wikipedia.org)
- It has been shown that sleep disturbances can have an influence on the suicidality of patients with bipolar disorder. (wikipedia.org)
- Therefore, sleep disturbances in bipolar disorder could also have a genetic basis. (wikipedia.org)
- Sleep disturbances in bipolar disorder are also an important marker for relapse. (wikipedia.org)
Seasonal affectiv9
- What is seasonal affective disorder (SAD) and its effects on running and how can they be overcome? (irunfar.com)
- Seasonal affective disorder, or SAD, affects a half million people each year, according to the National Alliance on Mental Illness. (irunfar.com)
- In general, though, seasonal affective disorder starts in fall or winter and ends in spring or early summer. (webmd.com)
- the best evidence to date that light is an effective antidepressant in seasonal affective disorder (SAD). (instantdaylite.com)
- We hope the guidelines will help physicians to explain some of the many questions that patients and family members ask about Seasonal Affective Disorder. (instantdaylite.com)
- We recommend that bright-light exposure be scheduled immediately on awakening in the treatment of most patients with seasonal affective disorder. (instantdaylite.com)
- Timed exposure to daylight-intensity light has become the treatment of choice for Seasonal Affective Disorder. (instantdaylite.com)
- You may have heard people referring to this as seasonal affective disorder (SAD), but the winter blues and SAD are two different things. (cmhakelowna.com)
- BLT is indicated by the American Psychiatric Association for the treatment of seasonal affective disorder. (medscape.com)
Biological3
- There is evidence that relapse in these disorders is associated with interplay between biological factors associated with the circadian pacemaker (a part of the brain that controls sleep and many other aspects of bodily function which change according to the time of day) and psychosocial factors. (newsroom.co.nz)
- Chronobiology is how clock systems impact us from a physiological and biological standpoint. (libsyn.com)
- Delayed sleep-wake phase disorder (DSWPD) is characterized by late bedtime and wake times and an inherent delay of biological rhythms compared to the natural daylight. (medlink.com)
Obsessive-Compulsi1
- There are many manifestations of anxiety disorders, some of which include panic disorders, phobias, obsessive compulsive disorder, and post-traumatic stress disorder. (issuu.com)
Chronotypes2
- However, the researchers at UCSF use the term ASP and appear to avoid labeling advanced sleepers or extreme morning chronotypes as having a so-called "disorder. (psychologytoday.com)
- We regularly publish news, articles and studies on chronobiology and chronotypes. (chronocollege.de)
Laboratory1
- Patients' home and the University of California San Diego, General Clinical Research Center, J. Christian Gillin Laboratory of Sleep and Chronobiology. (nih.gov)
Anxiety Disorders3
- Anxiety disorders are the most prevalent of mental health issues, with an estimated 1 in 10 Canadians affected by them [1]. (issuu.com)
- Anxiety disorders affect behavior, thoughts, emotions, and physical health, and are thought to be caused by a combination of neurobiological, genetic, and personal circumstances, combined with social and economic factors. (issuu.com)
- Fortunately, in many cases, anxiety disorders can be successfully treated and managed once they are recognized. (issuu.com)
Bipolar Disorders4
- Home Mood Bipolar Disorder Do Circadian-Modifying Treatments Work for Bipolar Disorders? (cet.org)
- Of all the conditions for which chronotherapy has been applied, bipolar disorders might be an especially rich intervention. (cet.org)
- Last, clinical and basic research demonstrate that individuals with bipolar disorders are unusually sensitive to changes in light exposure and timing. (cet.org)
- The use of the chronotherapies to treat the different mood states of bipolar disorders is thus a work in progress. (cet.org)
Delayed sleep ph1
- Prior names include delayed sleep phase syndrome and circadian rhythm sleep disorder, delayed sleep phase type. (medlink.com)
Parasomnias2
- [ 3 ] The DSM-IV-TR divided sleep disorders into 3 categories: Dyssomnias, Parasomnias, and Medical Psychiatric Disorders. (medscape.com)
- In children with non-REM (NREM) parasomnias, epilepsy, or nocturnal enuresis, PSG is a guideline recommendation if there is suspicion of sleep-disordered breathing or periodic limb movement disorder. (medscape.com)
Periodic1
- For nonrespiratory indications, standard use of PSG is indicated in children suspected of having periodic limb movement disorder (or RLS). (medscape.com)
Patients10
- Patients with bipolar disorder often have a less stable and more variable circadian activity. (wikipedia.org)
- It is also reported as a major problem by patients with borderline personality disorder (BPD) and is present in a surprising 14% of the general population in whom it appears to be a risk factor for a variety of negative psychiatric outcomes, including suicide 3 . (nature.com)
- In patients with circadian rhythm disorders, melatonin agonists may be used. (medscape.com)
- Exposure to bullying behaviours, resilience, and return to work self-efficacy in patients with common mental disorders. (uib.no)
- Clinical characteristics of patients seeking treatment for common mental disorders presenting with workplace bullying experiences. (uib.no)
- It aims to achieve optimal outcomes for patients with sleep disorders through integrated quality patient care, clinical education and research. (singhealthdukenus.com.sg)
- Studies have reported that 33% to 70% of patients with Alzheimer's disease (AD) have sleep-disordered breathing (SDB). (nih.gov)
- Patients with delayed sleep-wake phase disorder have otherwise normal sleep except that the sleep occurs later in the night and waking occurs later in the morning or early afternoon. (medlink.com)
- In patients with delayed sleep-wake phase disorder, the circadian rhythm is delayed when compared to the typical day-night schedule, and therefore, sleep onset and the natural wake time is delayed, usually by more than 2 hours, in relation to conventional or socially acceptable time. (medlink.com)
- Even so, patients with bipolar disorder are susceptible to environmental cues that alter circadian rhythms and trigger relapse. (medscape.com)
Apnea1
- Guideline recommendations are present for use of PSG in the assessment of congenital central alveolar hypoventilation syndrome, sleep-related hypoventilation related to neuromuscular disorders or chest wall deformities, and selected cases of primary sleep apnea of infancy. (medscape.com)
Cognitive Behavio1
- Six sections focused on each of the chronotherapeutic treatments: bright light therapy, sleep deprivation, dark therapy, melatonin, IPSRT, and cognitive behavioral therapy adapted for bipolar disorder (CBTI-BP). (cet.org)
Narcolepsy1
- It may be useful for treating pediatric attention deficit hyperactivity disorder (ADHD), as well as enuresis and, possibly, pediatric-onset narcolepsy. (medscape.com)
Psychiatric4
- Variable mood is an important feature of psychiatric disorders. (nature.com)
- Elevated rates of sleep problems exist among children and adolescents with neurodevelopmental, nonpsychiatric medical conditions and psychiatric disorders. (medscape.com)
- Reciprocal relationships occur between sleep disorders and comorbid psychiatric disorders. (medscape.com)
- Some investigators have considered delayed sleep-wake phase disorder as a marker or precursor for psychiatric and possibly neurologic issues. (medlink.com)
Exposure1
- Neurologic disorders caused by exposure to toxic substances through ingestion, injection, cutaneous application, or other method. (nih.gov)
Various sleep disorders1
- The diagnosis of a bipolar disorder is linked to various sleep disorders. (wikipedia.org)
Relapse1
- Relapse rates for these disorders are high and have consequent high costs for the individual, their family, mental health services and New Zealand society. (newsroom.co.nz)
People4
- This graph shows the total number of publications written about "Chronobiology Disorders" by people in this website by year, and whether "Chronobiology Disorders" was a major or minor topic of these publications. (sdsu.edu)
- Below are the most recent publications written about "Chronobiology Disorders" by people in Profiles. (sdsu.edu)
- With knowledge of chronobiology, in future people could individually manage their performance curve at work - for optimal results in their job. (konicaminolta.eu)
- If New Zealand is serious about improving the lives of people who experience serious mental disorders there needs to be funding of evidence-based psychotherapies to improve the costs to individuals, their families and wider society. (newsroom.co.nz)
Diagnosis1
- [ 1 ] Further investigation is needed to develop empirically based diagnosis and treatment of pediatric sleep disorders. (medscape.com)
Clinical1
- In infants with clinical evidence of sleep-related breathing disorder, PSG is a guideline recommendation for those with an apparent life-threatening event. (medscape.com)
Treat sleep disorders2
- Studies of the use of sedative-hypnotics to treat sleep disorders are limited to adults, and no FDA indications are approved for children younger than 18 years. (medscape.com)
- Using therapeutic light to treat sleep disorders often resolves or mitigates the mood problem. (instantdaylite.com)
Program1
- Since 2015, the Penn Chronobiology Program, now the Chronobiology and Sleep Institute (CSI) , has partnered with the the the Penn Sleep Centers and Division of Sleep Medicine to host the joint Annual Research Retreat . (upenn.edu)
Etiology3
- Sleep is known to play an important role in the etiology and maintenance of bipolar disorder. (wikipedia.org)
- Current research on circadian and sleep-wake processes shows that they play an important role in the etiology and maintenance of bipolar disorder. (wikipedia.org)
- The entire section has been renamed Sleep-Wake Disorders to highlight that etiology may be based in the inability to maintain alertness during the waking period. (medscape.com)
Causation1
- These categorical differences were eliminated in the DSM-5 to encourage the understanding that medical disorders and sleep disorders are intertwined and primary causation is usually not important. (medscape.com)
Mood disorder1
- SAD is actually a mood disorder related to seasonal changes in sunlight. (irunfar.com)
Phase disorder4
- Some experts refer to adults who tend to fall asleep between 7 to 9 P.M. and have trouble staying up until 10 P.M. as having a "disorder" and refer to this syndrome as advanced sleep phase disorder or ASPD. (psychologytoday.com)
- Delayed sleep-wake phase disorder may significantly impede academic and occupational achievements. (medlink.com)
- Delayed sleep-wake phase disorder must be distinguished from other sleep disorders as the treatment approach is different. (medlink.com)
- The circadian rhythm in delayed sleep-wake phase disorder is shifted later when compared to the social norms. (medlink.com)
Pediatric3
- Pediatric sleep disorders require careful, extended evaluation that includes interviewing care givers, the child, and assigning and reviewing sleep diaries. (medscape.com)
- Pediatric sleep disorders should be a primary consideration in all children. (medscape.com)
- Pediatric sleep disorders increasingly interfere with daily patient and family functioning. (medscape.com)
Instability2
- The social zeitgeber hypothesis therefore proposes that in bipolar disorder the fundamental circadian instability can be moderated by the stabilization of daily rhythms and zeitgeber. (wikipedia.org)
- Mood instability in BD disorder has been widely shown. (nature.com)
Study3
- A recent study also suggests that bipolar disorder is linked with an enhanced sensitivity to light. (wikipedia.org)
- Changes in work schedule affect the prevalence of shift work disorder among Norwegian nurses-a two year follow-up study. (uib.no)
- Medscape: What motivated you to study light therapy in bipolar disorder in the first place? (medscape.com)
Treatment5
- The authors conclude that light therapy is possibly an effective augmentation strategy in the treatment of bipolar disorder. (wikipedia.org)
- Healing the wounds of workplace bullying: Evaluating mental health and workplace participation among victims seeking treatment for common mental disorders. (uib.no)
- Benefits of music interventions for the treatment of psychosomatic disorders. (advancedbrain.com)
- Highly individualised psychotherapy treatment is helping those with recurrent mood disorders. (newsroom.co.nz)
- At the moment, treatment of recurrent mood disorders in New Zealand involves treatment of an acute episode of mood disturbance and a period of "stabilisation" in mental health services, and then discharge to general practice. (newsroom.co.nz)
MeSH1
- Chronobiology Disorders" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
Rhythm4
- Chronobiology, the science of rhythm and timing. (advancedbrain.com)
- There are a range of effective psychotherapies for recurrent mood disorders, one of which is Interpersonal and Social Rhythm Therapy. (newsroom.co.nz)
- Interpersonal and Social Rhythm Therapy is based on the evidence from chronobiology (circadian rhythm processes) and interpersonal therapy. (newsroom.co.nz)
- You've probably heard of the circadian rhythm , a term used in the science of chronobiology to describe the roughly 24-hour cycle followed by a wide variety of metabolic and physiological processes. (chronobiology.com)
Suicidal1
- Bipolar disorder is also linked with higher rates of suicidal ideation and suicidal attempts. (wikipedia.org)
Treatments1
- Marty was always looking for new scientific evidence and medical treatments that would help treat severe disorders," said David Dinges, chief of the division of sleep and chronobiology in Penn's psychiatry department. (sfn.org)