Combretum
Medicine, East Asian Traditional
Medicine, African Traditional
Cardiovascular effects of mollic acid glucoside, a 1alpha-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf. (1/13)
The cardiovascular effects of mollic acid glucoside (MAG), a 1alpha-hydroxycycloartenoid saponin extractive from Combretum molle R Br ex G Don (Combretaceae) leaf, have been investigated in some experimental animal paradigms. The plant extract (MAG, 5-80 microg/ml) produced concentration-dependent, significant (p < 0.05-0.001) negative inotropic and negative chronotropic effects on guinea pig isolated electrically driven left, and spontaneously beating right atrial muscle preparations, respectively. MAG also significantly reduced (p < 0.05-0.001) or abolished, in a concentration-dependent manner, the rhythmic, spontaneous contractions of portal veins isolated from healthy, normal Wistar rats. Like acetylcholine (ACh, 10-(8)-10-(5) M), the plant extract (5-80 microg/ml) produced concentration-related relaxations of rat isolated endothelium-containing thoracic aortic rings pre-contracted with noradrenaline (NA, 10-10(-10)-(5) M). The vasorelaxant effects of MAG in the aortic rings were markedly inhibited or annulled by N(G)-nitro-L-arginine methyl ester (L-NAME, 10(-5) M), a nitric oxide synthase inhibitor. Furthermore, MAG (2.5-40 mg/kg iv) caused dose-related, transient but significant reductions (p < 0.05-0.001) in the systemic arterial blood pressures and heart rates of anaesthetised normotensive and hypertensive rats. The results of this laboratory animal study indicate that MAG caused bradycardia, vasorelaxation and hypotension in the mammalian experimental models used. The vasorelaxant action of MAG was endothelium dependent, and was therefore possibly dependent on the synthesis and release of nitric oxide (NO). The findings of this study suggest that Combretum molle leaf may be used as a natural supplementary remedy in essential hypertension and in certain cases of cardiac dysfunctions in rural African communities. (+info)Bioactive pentacyclic triterpenes from the stems of Combretum laxum. (2/13)
(+info)Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. (3/13)
(+info)Antinociceptive effect on mice of the hydroalcoholic fraction and (-) epicatechin obtained from Combretum leprosum Mart & Eich. (4/13)
(+info)The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. (5/13)
(+info)Inhibitory and bactericidal potential of crude acetone extracts of Combretum molle (Combretaceae) on drug-resistant strains of Helicobacter pylori. (6/13)
Infection with Helicobacter pylori is strongly associated with a number of gastroduodenal pathologies. Antimicrobial resistance to commonly-used drugs has generated a considerable interest in the search for novel therapeutic compounds from medicinal plants. As an ongoing effort of this search, the susceptibility of 32 clinical strains of H. pylori and a reference strain-NCTC 11,638-was evaluated against five solvent extracts of Combretum molle, a plant widely used for the treatment of gastric ulcers and other stomach-related morbidities in South Africa. The extracts were screened for activity by the agar-well diffusion method, and the most active one of them was tested against the same strains by micro-broth dilution and time kill assays. Metronidazole and amoxicillin were included in these experiments as positive control antibiotics. The solvent extracts all demonstrated anti-H. pylori activity with zone diameters of inhibition between 0 and 38 mm. The most potent anti-H. pylori activity was demonstrated by the acetone extract, to which 87.5% of the clinical strains were susceptible. The minimum inhibitory concentration (MIC90) values for this extract ranged from 1.25 to 5.0 mg/mL while those for amoxicillin and metronidazole ranged from 0.001 to 0.94 mg/mL and from 0.004 to 5.0 mg/mL respectively. The acetone extract was highly bactericidal at a concentration of 2.5 and 5.0 mg/mL, with complete elimination of the test organisms in 24 hours. Its inhibitory activity was better than that of metronidazole (p<0.05) as opposed to amoxicillin (p<0.05). The results demonstrate that C. molle may contain therapeutically-useful compounds against H. pylori, which are mostly concentrated in the acetone extract. (+info)Anti-inflammatory effect of triterpene 3beta, 6beta, 16beta-trihydroxylup-20(29)-ene obtained from Combretum leprosum Mart & Eich in mice. (7/13)
(+info)Mechanisms of the antinociceptive action of (-) epicatechin obtained from the hydroalcoholic fraction of Combretum leprosum Mart & Eic in rodents. (8/13)
(+info)"Combretum" is a genus of flowering plants in the family Combretaceae, also known as the shrubs and small trees commonly found in tropical and subtropical regions around the world. These plants have various medicinal uses in different cultures. The active compounds in some species have been studied for potential anti-inflammatory, antimicrobial, and antimalarial properties. However, it's important to note that using herbal remedies can involve risks, and it's crucial to consult with a healthcare provider before starting any new treatment.
East Asian traditional medicine (ETAM) refers to the traditional medical systems that have been practiced in China, Japan, Korea, and other countries in this region for centuries. The most well-known forms of ETAM are Traditional Chinese Medicine (TCM), Kampo (Japanese traditional medicine), and Korean traditional medicine (KTM).
TCM is a comprehensive medical system that includes acupuncture, moxibustion, herbal medicine, dietary therapy, tuina (Chinese massage), and qigong (breathing exercises) among its modalities. TCM is based on the concept of balancing the flow of qi (vital energy) through a system of channels or meridians in the body.
Kampo is a Japanese adaptation of Chinese medicine that emphasizes the use of herbal formulas to treat illness and maintain health. Kampo practitioners often prescribe individualized herbal formulas based on the patient's unique pattern of symptoms, which are determined through careful diagnosis and examination.
KTM is a traditional Korean medical system that combines elements of Chinese and Japanese medicine with indigenous Korean practices. KTM includes acupuncture, moxibustion, herbal medicine, cupping, and various forms of manual therapy.
While ETAM has been practiced for centuries and has a rich cultural heritage, it is important to note that its safety and efficacy have not always been rigorously studied using modern scientific methods. As such, it is essential to consult with a qualified healthcare provider before pursuing any form of traditional medicine.
African traditional medicine (ATM) refers to the practices and beliefs regarding both physical and spiritual health and well-being that are indigenous to Africa. It includes various forms of healing, such as herbalism, spiritualism, and ancestral veneration, which may be practiced by traditional healers, including herbalists, diviners, and traditional birth attendants. These practices are often closely intertwined with the cultural, religious, and social beliefs of the community. It's important to note that the specific practices and beliefs can vary widely among different African cultures and communities.
A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.
Combretum - Wikipedia
combretum family - Encyclopedia of Life
COMBRETUM MICRANTHUM: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews
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Tree Species of Queen Elizabeth National Park
Combretaceae6
- Combretum, the bushwillows or combretums, make up the type genus of the family Combretaceae. (wikipedia.org)
- Combretaceae (Combretum Family) is a family of plants . (eol.org)
- Antihyperglycaemic activity of aqueous leaf extract of Combretum micranthum (Combretaceae) in normal and alloxan-induced diabetic rats. (webmd.com)
- Evaluation of the anti-inflammatory property of the extract of Combretum micranthum G. Don (Combretaceae). (webmd.com)
- Combretum , bushwillow atanapi kombretum , kalebet jinis genus tina kulawarga Combretaceae . (wikipedia.org)
- Combretum zeyheri , belongs to the family Combretaceae and is one of the most popular herbal plants in tropical and subtropical countries. (biomedcentral.com)
Bushwillow3
- citation needed] Typhlodromus combretum, a mite of the family Phytoseiidae, was discovered on a bushwillow plant and is named after this genus. (wikipedia.org)
- The class of chemical compounds known as combretastatins were first isolated from South African Bushwillow (Combretum caffrum), from which they get their name. (wikipedia.org)
- Combretum mossambicense , commonly known as the knobbly climbing bushwillow , is a scandent, often multi-stemmed shrub that spreads, reaching heights from 2 m to 3 m. (operationwildflower.org.za)
Species6
- As of April 2021, there are 272 accepted species of Combretum: Combretum aculeatum Vent. (wikipedia.org)
- The environments in which many combretum family species are known to live. (eol.org)
- Select an environment to see its combretum family species checklist. (eol.org)
- It is not a climbing species, unlike other Combretum species. (feedipedia.org)
- In Africa, Combretum species are well known in traditional medicine and used for various ailments and diseases ranging from heart and worm remedies to wound dressings, treatment of the mentally ill, scorpion stings and snake bites, to fever and microbial infections [ 9 ]. (biomedcentral.com)
- Among the park's vegetation, iconic tree species like Acacia albida, Ficus natalensis, Terminalia superba, Albizia coriaria, and Combretum molle, thrive and play vital roles in the park's ecosystem. (jewelsafaris.com)
Engl17
- Combretum alfredi Hance Combretum andongense Engl. (wikipedia.org)
- ex Kurz Combretum aphanopetalum Engl. (wikipedia.org)
- ex M.A.Lawson Combretum assimile Eichler Combretum atropurpureum Engl. (wikipedia.org)
- Diels Combretum aureonitens Engl. (wikipedia.org)
- Gilg Combretum auriculatum Engl. (wikipedia.org)
- Dalziel Combretum baumii Engl. (wikipedia.org)
- Gilg Combretum bipindense Engl. (wikipedia.org)
- Diels Combretum blepharopetalum Wickens Combretum boinensis Jongkind Combretum bracteatum (M.A.Lawson) Engl. (wikipedia.org)
- Diels Combretum brassiciforme Exell Combretum brevistylum Eichler Combretum brunneum Engl. (wikipedia.org)
- Kuntze Combretum camporum Engl. (wikipedia.org)
- ex M.A.Lawson Combretum chinense G.Don Combretum chionanthoides Engl. (wikipedia.org)
- Diels Combretum cinnabarinum Engl. (wikipedia.org)
- Combretum comosum G.Don Combretum conchipetalum Engl. (wikipedia.org)
- M.A.Lawson Combretum contractum Engl. (wikipedia.org)
- Combretum padoides Engl. (malawiflora.com)
- Combretum pisoniiflorum Engl. (malawiflora.com)
- Combretum menyhartii Engl. (zambiaflora.com)
Indicum1
- Combretum indicum L. (planterandforester.com)
Kraussii1
- Combretum kraussii Hochst. (co.zw)
Collinum1
- Combretum collinum Fresen. (wikipedia.org)
Steud3
- Combretum acutifolium Exell Combretum acutum M.A.Lawson Combretum adenogonium Steud. (wikipedia.org)
- Combretum punctatum Steud. (monaconatureencyclopedia.com)
- Combretum adenogonium Steud. (mozambiqueflora.com)
Seeds1
- Five new triterpene glucosides, quadranosides I−V (1−5), have been isolated from a MeOH extract of the seeds of Combretum quadrangulare, together with 13 known compounds. (canada.ca)
Loefl1
- Mitotic Studies on Combretum Loefl. (scirp.org)
Caffrum1
- Combretum cacoucia Exell ex Sandwith Combretum caffrum (Eckl. (wikipedia.org)
Micranthum17
- Combretum micranthum is a type of shrub that is used as a beverage or as medicine in parts of Western Africa. (webmd.com)
- Combretum micranthum might stimulate bile flow, which is important in digestion. (webmd.com)
- People use Combretum micranthum for high blood pressure , stomach upset, and many other conditions, but there is no scientific evidence to support these uses. (webmd.com)
- Combretum micranthum is possibly safe when used for up to 6 months. (webmd.com)
- There isn't enough reliable information to know if Combretum micranthum is safe to use when pregnant or breast-feeding. (webmd.com)
- Combretum micranthum leaf might lower blood sugar levels. (webmd.com)
- Taking Combretum micranthum along with diabetes medications might cause blood sugar to drop too low. (webmd.com)
- Taking Combretum micranthum along with medications that lower blood pressure might cause blood pressure to go too low. (webmd.com)
- Combretum micranthum leaf can decrease potassium levels. (webmd.com)
- Taking Combretum micranthum along with "water pills" might make potassium levels drop too low. (webmd.com)
- Combretum micranthum has most often been used by adults in doses of 200 mg by mouth twice daily for 6 months. (webmd.com)
- Hypertension treatment with Combretum micranthum or Hibiscus sabdariffa, as decoction or tablet: a randomized clinical trial. (webmd.com)
- In vitro activity of a Combretum micranthum extract against herpes simplex virus types 1 and 2. (webmd.com)
- Antioxidant and nephroprotection activities of Combretum micranthum: A phytochemical, in-vitro and ex-vivo studies. (webmd.com)
- Nephroprotective effect of Combretum micranthum G. Don in nicotinamide-streptozotocin induced diabetic nephropathy in rats: In-vivo and in-silico experiments. (webmd.com)
- Clinical efficacy of African traditional medicines in hypertension: A randomized controlled trial with Combretum micranthum and Hibiscus sabdariffa. (webmd.com)
- Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and thei" by C. Welch, J. Zhen et al. (jfda-online.com)
Apiculatum6
- Diels Combretum apiculatum Sond. (wikipedia.org)
- Red bush willow ( Combretum apiculatum Sond. (feedipedia.org)
- Combretum apiculatum is a deciduous, small to medium-sized tree growing to a height of 10 m. (feedipedia.org)
- A simulation of goat browsing indicated that browsing by mammals enhanced shoot growth and leaf production of Combretum apiculatum ( Rooke, 2003 ). (feedipedia.org)
- In South Africa, Combretum apiculatum was reported to be an indicator of mixed veld, an intermediary form of natural rangeland between sweetveld, which is palatable year-round, and sourveld, which is poorly palatable during winter ( Macaskill, 2016 ). (feedipedia.org)
- Combretum apiculatum foliage may contain high amounts of condensed tannins, though a proper quantification is needed (Lukhele et al. (feedipedia.org)
Trifoliatum1
- Annona muricata and Combretum trifoliatum were investigated against Acanthamoeba triangularis. (ua.pt)
Exell4
- Diels Combretum andradae Exell & J.G.García Combretum angolense Welw. (wikipedia.org)
- Diels Combretum barbatum G.Don Combretum batesii Exell Combretum bauchiense Hutch. (wikipedia.org)
- Exell Combretum capituliflorum Fenzl ex Schweinf. (wikipedia.org)
- Combretum capuronii Jongkind Combretum carringtonianum Exell & J.G.García Combretum caudatisepalum Exell & J.G.García Combretum celastroides Welw. (wikipedia.org)
Bertol2
- Combretum argenteum Bertol. (wikipedia.org)
- Diels Combretum butyrosum (G.Bertol. (wikipedia.org)
Hochst1
- Diels Combretum bracteosum (Hochst. (wikipedia.org)
Willow1
- Features Bush Willow (Combretum purpureum) flowers. (finevintageart.com)
Diels3
- Diels Combretum clarense Jongkind Combretum coccineum (Sonn. (wikipedia.org)
- Diels Combretum confertum (Benth. (wikipedia.org)
- Diels Combretum coursianum (H.Perrier) Jongkind Combretum cuspidatum Planch. (wikipedia.org)
Africa1
- Savannahs in Africa, in particular those growing on granitic soils, are often dominated by Combretum and its close relative Terminalia. (wikipedia.org)
Argyrotrichum1
- Combretum argyrotrichum Welw. (wikipedia.org)
Lawson2
- ex M.A.Lawson Combretum angustipetalum Chiov. (wikipedia.org)
- M.A.Lawson Combretum × confusum Merr. (wikipedia.org)
Aubl1
- Combretum laxum Aubl. (monaconatureencyclopedia.com)
Decandrum1
- Combretum decandrum Jacq. (wikipedia.org)
Family1
- Known occurrences, collected specimens and observations of combretum family. (eol.org)
Leaves1
- The leaves of Combretum zeyheri have been used as herbal medicine and have been reported to have pharmacological activity which includes anti-bacterial, anti-fungal, anticancer and antioxidant properties. (biomedcentral.com)
Rich1
- The Combretum rotundifolium Rich. (monaconatureencyclopedia.com)
Wild2
- Combretum capitatum De Wild. (wikipedia.org)
- Combretum demeusei De Wild. (wikipedia.org)