Commiphora
Medicine, Ayurvedic
Resins, Plant
Pregnenediones
A safe, effective, herbal antischistosomal therapy derived from myrrh. (1/27)
Schistosomiasis is a widespread helminthic disease. Treatment of schistosomiasis is based on chemotherapy with praziquantel, which is the drug of choice. Since resistance to praziquantel has been demonstrated, alternative drugs must be considered. Myrrh is an oleo-gum resin from the stem of the plant Commiphora molmol. This study was carried out on 204 patients with schistosomiasis. The drug was given at a dose of 10 mg/kg of body weight/day for three days, and induced a cure rate of 91.7%. Re-treatment of cases who did not respond with a dose of 10 mg/kg of body weight/day for six days gave a cure rate of 76.5%, increasing the overall cure rate to 98.09%. The drug was well tolerated, and side effects were mild and transient. Twenty cases provided biopsy specimens six months after treatment and none of them showed living ova. (+info)Further bisabolenes and dammarane triterpenes of Commiphora kua resin. (2/27)
From the resins of Commiphora kua a novel bisabolene; 6-hydroxy-2-methyl-5-(5'-hydroxy-1'(R),5'-dimethylhex-3'-enyl)-phenol together with two new dammarane triterpenes, 3beta,16beta,20(S),25-tetrahydroxydammar-23-ene and 3beta-acetoxy-16beta,20(S),25-trihydroxydammar-23-ene, have been isolated. In addition, being reported are known compounds identified as 2-methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol, 2-acetoxyfuranodienone, 2-methoxyfuranodienone, 3beta,16beta,20(R)-trihydroxydammar-24-ene and its acetate derivative, 3beta-acetoxy-16beta,20(R)-dihydroxydammar-24-ene, and beta-amyrin and its acetate derivative. 2-Methyl-5-(4'(S)-hydroxy-1'(R),5'-dimethylhex-5'-enyl)-phenol displayed fungicidal activity against Cladosporium cucumernum on TLC assay. (+info)Dammarane triterpenes of Commiphora confusa resin. (3/27)
Fractionation of a steam distilled residue of Commiphora confusa resin has yielded four novel dammarane triterpenes characterised as (20S)-3beta-acetoxy-12beta,16beta-trihydroxydammar-24-ene, (20S)-12beta,16beta-trihydroxydammar-24-ene-3beta-O-beta-glucopyranoside, (20S)-3beta-acetoxy-12beta,16beta,25-tetrahydroxydammar-23-ene, and (20S)-3beta,12beta,16beta,25-pentahydroxydammar-23-ene. The known compounds beta-amyrin, 3beta-amyrinacetate, 2-methoxyfuranodienone, 2-acetoxyfuranodienone, (20R)-3beta-acetoxy-16beta-dihydroxydammar-24-ene, (20R)-3beta,16beta-trihydroxydammar-24-ene, 3beta-acetoxy-16beta-hydroxydammar-24-ene, 3beta-hydroxydammar-24-ene, 3beta-acetoxydammar-24-ene, and beta-sistosterol were also isolated from the same extract. The structures of the compounds were determined using spectroscopic, physical, and chemical methods. (+info)Absolute stereostructures of polypodane-type triterpenes, myrrhanol A and myrrhanone A, from guggul-gum resin (the resin of Balsamodendron mukul). (4/27)
Two new polypodane-type triterpenes, myrrhanol A and myrrhanone A, were isolated from the 50% aqueous methanolic extract of guggul-gum resin [the resin of Balsamodendron (=Commiphora) mukul HOOK]. The structures of the new constituents, including their absolute configurations, were determined on the basis of chemical and physicochemical evidence. (+info)Myrrh--Commiphora chemistry. (5/27)
Myrrh and opopanax has been used throughout history in incense and as a perfume. Since Bible times it has been used for the treatment of wounds. The first attempts to identify content compounds were almost 100 years ago. In this review we discuss the present state of knowledge in the chemistry of substances of Commiphora spp. (+info)Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak. (6/27)
The present study was undertaken to gain insights into the molecular mechanism of cell death (apoptosis) by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, using PC-3 human prostate cancer cells as a model. The viability of PC-3 cells, but not a normal prostate epithelial cell line (PrEC), was reduced significantly on treatment with guggulsterone in a concentration-dependent manner. Guggulsterone-mediated suppression of PC-3 cell proliferation was not due to perturbation in cell cycle progression but caused by apoptosis induction characterized by appearance of subdiploid cells and cytoplasmic histone-associated DNA fragmentation. Guggulsterone-induced apoptosis was associated with induction of multidomain proapoptotic Bcl-2 family members Bax and Bak. Interestingly, the expression of antiapoptotic proteins Bcl-2 and Bcl-xL was initially increased in guggulsterone-treated PC-3 cells but declined markedly following a 16- to 24-hour treatment with guggulsterone. Ectopic expression of Bcl-2 in PC-3 cells failed to confer significant protection against guggulsterone-induced cell death. On the other hand, SV40 immortalized mouse embryonic fibroblasts derived from Bax-Bak double knockout mice were significantly more resistant to guggulsterone-induced cell killing compared with wild-type cells. Guggulsterone treatment resulted in cleavage (activation) of caspase-9, caspase-8, and caspase-3, and guggulsterone-induced cell death was significantly attenuated in the presence of general caspase inhibitor as well as specific inhibitors of caspase-9 and caspase-8. In conclusion, the present study indicates that caspase-dependent apoptosis by guggulsterone is mediated in part by Bax and Bak. (+info)Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni. (7/27)
This work has been carried out to investigate the effect of Schistosoma mansoni infection on mice livers after treatment with the ethanolic extract of Citrus reticulata root or the oleo-resin extract from Myrrh of Commiphora molmol tree (Mirazid), as a new antishistosomal drug. Marker enzymes for different cell organelles were measured; succinate dehydrogenase (SDH); lactate dehydrogenase (LDH) and its isoenzymes; glucose-6-phosphatase (G-6-Pase); acid phosphatase (AP) and 5'- nucleotidase. Liver function enzymes; aspartate aminotransferase (AST); alanine aminotransferase (ALT), and alkaline phosphatase (ALP) were also estimated. Parasitological studies through ova count and worm burden will also be taken into consideration. The results showed a marked reduction in SDH, LDH, AST, and ALT enzyme activities and a significant increase in G-6-Pase, AP, 5'- nucleotidase, and ALP after S. mansoni infection. A noticeable alteration in LDH subunits were also noticed. Treatment with C. reticulata or Mirazid improved all the previous enzyme activities with a noticeable reduction in ova count and worm burden. (+info)Guggulsterone inhibits osteoclastogenesis induced by receptor activator of nuclear factor-kappaB ligand and by tumor cells by suppressing nuclear factor-kappaB activation. (8/27)
Bone resorption is commonly associated with aging and with certain types of cancer, including multiple myeloma and breast cancer. What induces bone resorption is not fully understood, but the role of osteoclasts is well established. Recently, receptor activator of nuclear factor-kappaB (NF-kappaB) ligand (RANKL), a member of the tumor necrosis factor superfamily, was implicated as a major mediator of bone resorption, suggesting that agents that can suppress RANKL signaling have the potential to inhibit bone resorption or osteoclastogenesis. Guggulsterone [4,17(20)-pregnadiene-3,16-dione], isolated from the guggul tree Commiphora mukul and used to treat osteoarthritis and bone fractures, was recently shown to antagonize the farnesoid X receptor, decrease the expression of bile acid-activated genes, and suppress the NF-kappaB activation induced by various carcinogens. We investigated whether guggulsterone could modulate RANKL signaling and osteoclastogenesis induced by RANKL or tumor cells. We found that treatment of monocytes with guggulsterone suppressed RANKL-activated NF-kappaB activation (as indicated by gel-shift assay) and that this suppression correlated with inhibition of IkappaBalpha kinase and phosphorylation and degradation of IkappaBalpha, an inhibitor of NF-kappaB. Guggulsterone also suppressed the differentiation of monocytes to osteoclasts in a dose-dependent and time-dependent manner. Suppression of osteoclastogenesis by the NF-kappaB-specific inhibitory peptide implies a link between NF-kappaB and osteoclastogenesis. Finally, differentiation to osteoclasts induced by coincubating human breast tumor cells (MDA-MB-468) or human multiple myeloma (U266) cells with monocytes was also completely suppressed by guggulsterone. Collectively, our results indicate that guggulsterone suppresses RANKL and tumor cell-induced osteoclastogenesis by suppressing the activation of NF-kappaB. (+info)'Commiphora' is a genus of shrubs and trees in the family Burseraceae, commonly known as myrrh trees. They are native to dry regions of Africa and Arabia. The bark and resin of several species have been used traditionally for medicinal purposes, such as treating wounds, skin infections, and digestive disorders. Myrrh oil is also used in aromatherapy and as a flavoring agent in foods and beverages. Some studies suggest that myrrh extracts may have anti-inflammatory, antimicrobial, and antioxidant properties, but more research is needed to confirm these effects and determine their safety and efficacy.
Ayurvedic medicine, also known as Ayurveda, is a traditional system of medicine that has been practiced in India for thousands of years. It is based on the belief that health and wellness depend on a delicate balance between the mind, body, and spirit. The goal of Ayurvedic medicine is to promote good health, rather than fight disease.
In Ayurveda, each person has a unique constitution, or dosha, that is determined by the balance of three energies: Vata (air and space), Pitta (fire and water), and Kapha (water and earth). These doshas are believed to govern all physical and mental processes and to be responsible for an individual's physical and mental health.
Ayurvedic treatments may include herbal remedies, special diets, detoxification programs, meditation, yoga, and massage therapy. The aim of Ayurvedic medicine is to cleanse the body of toxins, balance the doshas, and promote good health and well-being.
It's important to note that while some people find Ayurvedic practices helpful for maintaining their overall health, there is limited scientific evidence supporting the safety and effectiveness of many Ayurvedic treatments. Additionally, some Ayurvedic products may contain harmful levels of heavy metals, such as lead, mercury, and arsenic, which can be toxic if ingested or absorbed through the skin. It's important to consult with a qualified healthcare provider before starting any new treatment regimen, including Ayurvedic medicine.
In a medical context, "resins, plant" refer to the sticky, often aromatic substances produced by certain plants. These resins are typically composed of a mixture of volatile oils, terpenes, and rosin acids. They may be present in various parts of the plant, including leaves, stems, and roots, and are often found in specialized structures such as glands or ducts.
Plant resins have been used for centuries in traditional medicine and other applications. Some resins have antimicrobial, anti-inflammatory, or analgesic properties and have been used to treat a variety of ailments, including skin conditions, respiratory infections, and pain.
Examples of plant resins with medicinal uses include:
* Frankincense (Boswellia spp.) resin has been used in traditional medicine to treat inflammation, arthritis, and asthma.
* Myrrh (Commiphora spp.) resin has been used as an antiseptic, astringent, and anti-inflammatory agent.
* Pine resin has been used topically for its antimicrobial and anti-inflammatory properties.
It's important to note that while some plant resins have demonstrated medicinal benefits, they should be used with caution and under the guidance of a healthcare professional. Some resins can have adverse effects or interact with medications, and it's essential to ensure their safe and effective use.
Pregnenediones are a class of steroid hormones that contain a pregnane structure, which is a skeleton formed by four fused cyclohexane rings. Specifically, pregnenediones are characterized by having a ketone group (a carbonyl group, -C=O) at the 20th carbon position of this pregnane structure. They can be further classified into various subgroups based on the presence and location of other functional groups in the molecule.
Pregnenediones are not typically used as medications, but they do play important roles in the human body. For example, progesterone is a naturally occurring pregnenedione that plays a crucial role in maintaining pregnancy and preparing the uterus for childbirth. Other pregnenediones may also have hormonal activity or serve as intermediates in the synthesis of other steroid hormones.
A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.
Commiphora
Commiphora angolensis
Commiphora wightii
Commiphora aprevalii
Commiphora schimperi
Commiphora kataf
Commiphora africana
Commiphora madagascariensis
Commiphora gileadensis
Commiphora socotrana
Commiphora guidottii
Commiphora saxicola
Commiphora kua
Commiphora caudata
Commiphora myrrha
Somali Acacia-Commiphora bushlands and thickets
Northern Acacia-Commiphora bushlands and thickets
Southern Acacia-Commiphora bushlands and thickets
Alphonse Révillon d'Apreval
Curzerene
Balm of Gilead
List of Ngorongoro Crater plants
Opopanax (perfumery)
List of plants of Burkina Faso
List of trifoliate plants
Myrrha
Spathionema
Burseraceae
Onycha
Amyris
Commiphora - Wikipedia
Commiphora Myrrha Resin (myrhová pryskyřice) | LUSH
Guggul Uses & Benefits of Guggul, Commiphora Mukul
Flora of Zimbabwe: Cultivated plants: genus page: Commiphora
Flora of Zimbabwe: Species information: individual images: Commiphora edulis
Preliminary study of therapeutic efficacy of a new fasciolicidal drug derived from Commiphora molmol (myrrh). in: The American...
Reactive Oxygen Species-Dependent Apoptosis by Gugulipid Extract of Ayurvedic Medicine Plant Commiphora mukul in Human Prostate...
Commiphora habessinica subsp. tanganyikensis J.B.Gillett | Plants of the World Online | Kew Science
Flora of Malawi: Individual record no: 119041: Commiphora mossambicensis
Commiphora harveyi
Commiphora grandifolia Engl.
Central Tanzania
Commiphora playfairii var. benadirensis
Guggul (Commiphora mukul) - Supaveda
commiphora myrrha Archives - NYC Aromatica
Myrrh, Commiphora Myrrha | My Site
Myrrh (Commiphora myrrha) - HAWAII PHARM
Commiphora africana | Henriette's Herbal Homepage
MYRRH Commiphora myrrha, 5ml. - Naturales
Commiphora gileadensis Images - Useful Tropical Plants
Commiphora saxicola (Burseraceae) image 43473 at
Guggul živica - Commiphora mukul - PredajBylín.sk
Myrrh Oil Commiphora myrrha - Forest Clay
Commiphora madagascariensis Jacq. [ Amyris commiphora Roxb.]
Myrrh (Commiphora myrrha) Essential Oil - Wingsets
Buy South-Indian Commiphora, Green commiphora Online
Myrrh - Commiphora Wightii extract - Naturalia Beauty UK
Commiphora mukul (Guggla) - VCA Healthcare Pvt Ltd
Guggulu - Commiphora Wightii pure Exporter from Rajkot
Myrrha8
- Commiphora myrrha (Nees) Engl. (llifle.com)
- Decrease quantity for MYRRH Commiphora myrrha, 5ml. (naturales.no)
- Increase quantity for MYRRH Commiphora myrrha, 5ml. (naturales.no)
- Dry best quality resin of Commiphora myrrha in a base of organic alcohol. (parisvitamin.com)
- Commiphora myrrha (Nees) Engler, fam. (theoilshoppe.com)
- Myrrh, like frankincense is harvested from Commiphora myrrha trees. (bakhoorstoreincense.com)
- You might wonder how Commiphora Erythraea stacks up against its close relative, Commiphora Myrrha. (igneousproducts.com)
- Myrrh is a Biblically significant, reddish-brown Resin from the thorny Commiphora Myrrha tree, native to East Africa. (aromafume.com)
Engl26
- Commiphora alaticaulis J.B.Gillett & Vollesen Commiphora anacardiifolia Dinter & Engl. (wikipedia.org)
- A.Weeks & Gostel Commiphora angolensis Engl. (wikipedia.org)
- Commiphora antunesii Engl. (wikipedia.org)
- Commiphora aprevalii Guillaumin, endemic to Madagascar Commiphora arafy H.Perrier Commiphora arenaria Thulin Commiphora baluensis Engl. (wikipedia.org)
- Commiphora boranensis Vollesen Commiphora brevicalyx H.Perrier Commiphora buruxa Swanepoel Commiphora caerulea Burtt Commiphora campestris Engl. (wikipedia.org)
- Commiphora cervifolia Van der Walt Commiphora chaetocarpa J.B.Gillett Commiphora chevalieri Engl. (wikipedia.org)
- Commiphora chiovendana J.B.Gillett ex Thulin Commiphora ciliata Vollesen Commiphora coleopsis H.Perrier Commiphora confusa Vollesen Commiphora corrugata J.B.Gillett & Vollesen Commiphora crenatoserrata Engl. (wikipedia.org)
- Commiphora dinteri Engl. (wikipedia.org)
- Commiphora discolor Mendes Commiphora drake-brockmanii Sprague Commiphora dulcis Engl. (wikipedia.org)
- Commiphora edulis (Klotzsch) Engl. (wikipedia.org)
- Commiphora erlangeriana Engl. (wikipedia.org)
- Commiphora fulvotomentosa Engl. (wikipedia.org)
- Commiphora glandulosa Schinz Commiphora glaucescens Engl. (wikipedia.org)
- Commiphora gracilifrondosa Dinter ex Van der Walt Commiphora grandifolia Engl. (wikipedia.org)
- Commiphora grosswelleri Engl. (wikipedia.org)
- Commiphora guerichiania Engl. (wikipedia.org)
- Commiphora guillauminii H.Perrier Commiphora gurreh Engl. (wikipedia.org)
- Commiphora grandifolia Engl. (plantillustrations.org)
- 2 267678 Commiphora grandifolia Engl. (plantillustrations.org)
- Commiphora coriacea Engl. (llifle.com)
- Commiphora molmol (Engl. (llifle.com)
- Commiphora rivae Engl. (llifle.com)
- Commiphora agallocha Engl. (plantillustrations.org)
- Commiphora spondioides Engl. (mozambiqueflora.com)
- Commiphora fischeri Engl. (zambiaflora.com)
- Commiphora opobalsamum (L.) Engl. (plantillustrations.org)
Mukul2
- Guggul is a yellowish resin, which is secreted by a small, thorny mukul myrrh tree called commiphora mukul. (iloveindia.com)
- Gugulipid (GL), extract of Indian Ayurvedic medicinal plant Commiphora mukul , has been used to treat a variety of ailments. (aspetjournals.org)
Resin3
- Myrrh (from the stem of the Commiphora molmol tree) is an oleo gum resin that may prove efficacious for the treatment of fascioliasis. (ajtmh.org)
- Myrrh is a resin that is derived from the bark of the Commiphora tree, which is native to Africa and the Middle East. (hawaiipharm.eu)
- Derived from the resin of the Commiphora Erythraea tree, native to the Arabian Peninsula and northeastern Africa, this precious substance has woven its way through cultural, spiritual, and medicinal traditions. (igneousproducts.com)
Burseraceae2
- The genus of the myrrhs, Commiphora, is the most species-rich genus of flowering plants in the frankincense and myrrh family, Burseraceae. (wikipedia.org)
- Encyclopedia/TREES/Family/Burseraceae/23261/Commiphora_playfairii_var. (llifle.com)
Wightii2
- Providing you the best range of commiphora wightii pure with effective & timely delivery. (faithangelgroup.in)
- Customers can avail Commiphora wightii From us. (faithangelgroup.in)
Species3
- Products from many species of Commiphora have been used for various purposes, sometimes as timber, building material, and natural fencing, but more often valued for the aromatic resins produced by several members of the genus. (wikipedia.org)
- 181 species are accepted: Commiphora acuminata Mattick Commiphora africana (A.Rich. (wikipedia.org)
- Commiphora species are deciduous and for most of the year the trees are without leaves, making identification difficult. (africa-seeds.com)
Genus2
- Commiphora can serve as a model genus for understanding plant evolution in the drier regions of the Old World tropics, particularly in eastern continental Africa and Madagascar, where diversity in the genus is concentrated. (wikipedia.org)
- The closely related sister genus to Commiphora, Bursera, has been used as a model genus to study patterns of evolution in the New World seasonally dry tropical forests. (wikipedia.org)
Jacq2
- 4151.000 Commiphora Jacq. (co.zw)
- 6 267735 Commiphora madagascariensis Jacq. (plantillustrations.org)
Edulis1
- Commiphora edulis subsp. (mozambiqueflora.com)
Africana1
- Commiphora africana (A. Rich. (henriettes-herb.com)
Gileadensis2
- Commiphora gardoensis J.B.Gillett ex Thulin Commiphora gariepensis Swanepoel Commiphora giessii Van der Walt Commiphora gileadensis (L.) C.Chr. (wikipedia.org)
- Commiphora gileadensis (L.) C.Chr. (plantillustrations.org)
Subsp4
- Commiphora habessinica subsp. (kew.org)
- Cited as Commiphora habessinica subsp. (kew.org)
- Commiphora eminii subsp. (mozambiqueflora.com)
- Commiphora pyracanthoides subsp. (mozambiqueflora.com)
Mossambicensis1
- Commiphora mossambicensis (Oliv. (malawiflora.com)
Molmol1
- Preliminary study of therapeutic efficacy of a new fasciolicidal drug derived from Commiphora molmol (myrrh). (ajtmh.org)
Caudata1
- Commiphora caudata (Wight & Arn. (wikipedia.org)
Erythraea6
- What is Commiphora Erythraea Used For? (igneousproducts.com)
- Commiphora Erythraea, commonly known as myrrh, has fascinated civilizations for centuries with its rich history, captivating aroma, and versatile applications. (igneousproducts.com)
- In this comprehensive article, we delve into the multifaceted world of Commiphora Erythraea and explore its diverse uses across various domains. (igneousproducts.com)
- Its versatility and subtle differences make Commiphora Erythraea an excellent choice for various purposes. (igneousproducts.com)
- Commiphora Erythraea has been revered for its potential health benefits since ancient times. (igneousproducts.com)
- How is Commiphora Erythraea used in aromatherapy? (igneousproducts.com)
Guidottii1
- Commiphora guidottii Chiov. (wikipedia.org)
Habessinica1
- Commiphora habessinica var. (llifle.com)
Opobalsamum1
- Commiphora opobalsamum), producing balsam of Mecca. (wikipedia.org)
Chiov6
- Used indirectly by the San bushmen to poison their arrow tips for hunting Commiphora alata Chiov. (wikipedia.org)
- Commiphora benguelensis Swanepoel Commiphora berardellii Chiov. (wikipedia.org)
- Commiphora cuneifolia Baker Commiphora cyclophylla Chiov. (wikipedia.org)
- Commiphora engleri Guillaumin Commiphora enneaphylla Chiov. (wikipedia.org)
- Commiphora gorinii Chiov. (wikipedia.org)
- Commiphora cuspidata Chiov. (llifle.com)
Amyris1
- Amyris commiphora Roxb. (plantillustrations.org)
Extract1
- Paracress Extract, Commiphora and Wakame gently relaxes skin to appear plumper and youthful looking. (lamav.com)
Page1
- Cite this page: "Commiphora playfairii var. (llifle.com)
Essential1
- Commiphora Erythraea's aroma can be enjoyed through essential oil diffusers, inhalation from a cloth, or by incorporating myrrh-infused products into the environment for a soothing ambiance. (igneousproducts.com)
Rarely1
- Leaves in Commiphora are pinnately compound (or very rarely unifoliolate). (wikipedia.org)