Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.
A group of DITERPENES cyclized into 3-ring PHENANTHRENES.
A group of DITERPENES cyclized into 2-rings with a side-chain.
A group of DITERPENES cyclized into four rings.
A large plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. They have a milky sap and a female flower consisting of a single pistil, surrounded by numerous male flowers of one stamen each. Euphorbia hirta is rarely called milkweed but that name is normally used for ASCLEPIAS.
A plant genus of the family FABACEAE. The common name of "Bird-Of-Paradise" is also used for other plants such as Heliconia (HELICONIACEAE) and Strelitzia (STRELITZIACEAE) and some birds. The common name of "Cat's-Claw" is more often used with UNCARIA. The common name of "Pernambuco" also refers to a state in Brazil. Furanoditerpenoid lactones and caesalpin are produced by members of this genus.
A genus in the mint family (LAMIACEAE).
A plant family of the order Lamiales, subclass Asteridae, class Magnoliopsida. The leaves are opposite or whorled. The flowers are aggregated in spikes, clusters, or racemes.
A plant genus of the family CUPRESSACEAE which should not be confused with other cedar and cypress trees of THUJA or CUPRESSUS genera.
A plant genus of the family CISTACEAE. The common name of rock rose is also sometimes used with the closely related Helianthemum genus (CISTACEAE).
A plant family of the order Pinales, class Pinopsida, division Coniferophyta (conifers). They are mainly resinous, aromatic evergreen trees.
The outer layer of the woody parts of plants.
A plant genus of the family LAMIACEAE that contains pimarane-type diterpenes. Several species of Orthosiphon are also called Java tea.
A plant genus of the family ANNONACEAE. Members contain 8-oxopolyalthiaine.
A plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mainly trees and shrubs. Many members contain mucilage and COUMARINS.
A plant genus of the family ASTERACEAE. Members contain scandenolide (a sesquiterpene lactone) and germacranolides.
Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard.
The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.
The above-ground plant without the roots.
A plant genus of the family CUPRESSACEAE.
A class in the phylum CNIDARIA, comprised mostly of corals and anemones. All members occur only as polyps; the medusa stage is completely absent.
A plant genus of the family TAXODIACEAE. Its POLLEN is one of the major ALLERGENS.
A plant genus in the family CAPRIFOLIACEAE. The common name derives from its traditional use for menstrual cramps. It is a source of viburnine, valerianic acid, vibsanin, and ursolic acid. Note that true cranberry is VACCINIUM MACROCARPON.
SESQUITERPENES cyclized into two adjoining rings, one being 7-carbons and the other is 5-carbons.
A plant genus of the family FLACOURTIACEAE. Members contain casearins which are clerodane type DITERPENES.
A plant genus of the family Plantaginaceae. Members contain thyrsiflorin and other scopadulane (labdane) type DITERPENES.
A class of compounds composed of repeating 5-carbon units of HEMITERPENES.
Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).
A plant species of the Salvia genus known as a spice and medicinal plant.
A plant family of the order Ranunculales, subclass Magnoliidae, class Magnoliopsida. Members are mostly vines and shrubs and they contain isoquinoline alkaloids, some of which have been used as arrow poisons.
Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals.
Flammable, amorphous, vegetable products of secretion or disintegration, usually formed in special cavities of plants. They are generally insoluble in water and soluble in alcohol, carbon tetrachloride, ether, or volatile oils. They are fusible and have a conchoidal fracture. They are the oxidation or polymerization products of the terpenes, and are mixtures of aromatic acids and esters. Most are soft and sticky, but harden after exposure to cold. (From Grant & Hackh's Chemical Dictionary, 5th ed & Dorland, 28th ed)
The figwort plant family of the order Lamiales. The family is characterized by bisexual flowers with tubular corollas (fused petals) that are bilaterally symmetrical (two-lips) and have four stamens in most, two of which are usually shorter.
A division of predominantly marine EUKARYOTA, commonly known as brown algae, having CHROMATOPHORES containing carotenoid PIGMENTS, BIOLOGICAL. ALGINATES and phlorotannins occur widely in all major orders. They are considered the most highly evolved algae because of their well-developed multicellular organization and structural complexity.
A plant genus of the family LILIACEAE. Members of this genus produce imperialine, a steroidal alkaloid which acts at muscarinic receptors.
I'm sorry for any confusion, but "Paraguay" is not a medical term and does not have a medical definition. Paraguay is a country located in the central part of South America, bordered by Argentina to the south and southwest, Bolivia to the north and west, and Brazil to the east and northeast. If you have any questions related to medical terminology or health-related topics, I would be happy to help!
A genus of trees in the Lamiaceae family containing assorted flavonoids with possible analgesic and antineoplastic properties. The fruit of these trees is used in herbal preparations.
A plant division. They are simple plants that lack vascular tissue and possess rudimentary rootlike organs (rhizoids). Like MOSSES, liverworts have alternation of generations between haploid gamete-bearing forms (gametophytes) and diploid spore-bearing forms (sporophytes).
A plant genus in the family PINACEAE, order Pinales, class Pinopsida, division Coniferophyta.
A plant genus of the family ARISTOLOCHIACEAE. Species of this genus have been used in traditional medicine but they contain aristolochic acid which is associated with nephropathy. These are sometimes called 'snakeroot' but that name is also used with a number of other plants such as POLYGALA; SANICULA; ASARUM; ARISTOLOCHIA; AGERATINA; and others.
The characteristic three-dimensional shape of a molecule.
A plant genus of the LAMIACEAE family. It is known as a spice and medicinal plant.
A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of "daisy" refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.
A mass spectrometric technique that is used for the analysis of a wide range of biomolecules, such as glycoalkaloids, glycoproteins, polysaccharides, and peptides. Positive and negative fast atom bombardment spectra are recorded on a mass spectrometer fitted with an atom gun with xenon as the customary beam. The mass spectra obtained contain molecular weight recognition as well as sequence information.
A plant genus of the family EUPHORBIACEAE. The common name of dragon's blood is also used for DRACAENA and Daemonorops (ARECACEAE). Croton tiglium is the source of CROTON OIL.
A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
Spectrophotometry in the infrared region, usually for the purpose of chemical analysis through measurement of absorption spectra associated with rotational and vibrational energy levels of molecules. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
A product of hard secondary xylem composed of CELLULOSE, hemicellulose, and LIGNANS, that is under the bark of trees and shrubs. It is used in construction and as a source of CHARCOAL and many other products.
Sesquiterpenes are a class of terpenes consisting of three isoprene units, forming a 15-carbon skeleton, which can be found in various plant essential oils and are known for their diverse chemical structures and biological activities, including anti-inflammatory, antimicrobial, and cytotoxic properties.
Expanded structures, usually green, of vascular plants, characteristically consisting of a bladelike expansion attached to a stem, and functioning as the principal organ of photosynthesis and transpiration. (American Heritage Dictionary, 2d ed)
A republic stretching from the Indian Ocean east to New Guinea, comprising six main islands: Java, Sumatra, Bali, Kalimantan (the Indonesian portion of the island of Borneo), Sulawesi (formerly known as the Celebes) and Irian Jaya (the western part of New Guinea). Its capital is Djakarta. The ethnic groups living there are largely Chinese, Arab, Eurasian, Indian, and Pakistani; 85% of the peoples are of the Islamic faith.
Phenanthrenes are aromatic hydrocarbons consisting of three benzene rings fused together in a linear arrangement, commonly found in various plants and some animals, and can act as precursors for certain steroid hormones or exhibit pharmacological activities with potential therapeutic uses.
The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Parts of plants that usually grow vertically upwards towards the light and support the leaves, buds, and reproductive structures. (From Concise Dictionary of Biology, 1990)
Methods of investigating the effectiveness of anticancer cytotoxic drugs and biologic inhibitors. These include in vitro cell-kill models and cytostatic dye exclusion tests as well as in vivo measurement of tumor growth parameters in laboratory animals.
Changing an open-chain hydrocarbon to a closed ring. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
Any compound that contains a constituent sugar, in which the hydroxyl group attached to the first carbon is substituted by an alcoholic, phenolic, or other group. They are named specifically for the sugar contained, such as glucoside (glucose), pentoside (pentose), fructoside (fructose), etc. Upon hydrolysis, a sugar and nonsugar component (aglycone) are formed. (From Dorland, 28th ed; From Miall's Dictionary of Chemistry, 5th ed)
Substances that are destructive to protozoans.
Determination of the spectra of ultraviolet absorption by specific molecules in gases or liquids, for example Cl2, SO2, NO2, CS2, ozone, mercury vapor, and various unsaturated compounds. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
The usually underground portions of a plant that serve as support, store food, and through which water and mineral nutrients enter the plant. (From American Heritage Dictionary, 1982; Concise Dictionary of Biology, 1990)
A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5.

Antagonistic effects of extract from leaves of ginkgo biloba on glutamate neurotoxicity. (1/2175)

AIM: To determine whether the extract of leaves of Ginkgo biloba L (EGb) and several active constituents of EGb have protective effects against glutamate (Glu)-induced neuronal damage. METHODS: Microscopy and image analysis of nucleus areas in the arcuate nuclei (AN) of mice were made. The neuronal viability in primary cultures from mouse cerebral cortex was assessed using MTT [3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide] staining and the intracellular free calcium concentration ([Ca2+]i) of single neuron was measured using Fura-2. RESULTS: EGb (2.5 mg.L-1) and its constituent ginkgolide B (Gin B, 2 mg.L-1) protected the neuronal viability against Glu-induced injury, and prevented the Glu-induced elevation in [Ca2+]i. EGb (3-10 mg.kg-1) attenuated the decrease of nucleus areas in arcuate nuclei induced by Glu (1 g.kg-1, s.c.). CONCLUSION: EGb and Gin B prevent neurons from Glu neurotoxicity through reduction of the rise in [Ca2+]i.  (+info)

A common pharmacophore for cytotoxic natural products that stabilize microtubules. (2/2175)

Taxol (paclitaxel), a complex diterpene obtained from the Pacific yew, Taxus brevifolia, is arguably the most important new drug in cancer chemotherapy. The mechanism of cytotoxic action for paclitaxel-i.e., the stabilization of microtubules leading to mitotic arrest-is now shared by four recently identified natural products, eleutherobin, epothilones A and B, and discodermolide. Their ability to competitively inhibit [3H]paclitaxel binding to microtubules strongly suggests the existence of a common binding site. Recently, we have developed nonaromatic analogues of paclitaxel that maintain high cytotoxicity and tubulin binding (e.g., nonataxel). We now propose a common pharmacophore that unites paclitaxel, nonataxel, the epothilones, eleutherobin, and discodermolide, and rationalizes the extensive structure-activity relationship data pertinent to these compounds. Insights from the common pharmacophore have enabled the development of a hybrid construct with demonstrated cytotoxic and tubulin-binding activity.  (+info)

On the complexities of ceramide changes in cells undergoing apoptosis: lack of evidence for a second messenger function in apoptotic induction. (3/2175)

The generation of cellular ceramides as a second messenger has been implicated as a regulatory and required step for the induction of apoptosis. In this study, we have applied a recently developed mass spectrometric technique to the determination of changes in physiological ceramide levels during apoptosis induced by tumor necrosis factor plus cycloheximide in U937 cells and the chemical agents anisomycin or geranylgeraniol in HL-60 cells. The mass spectrometric method has significant advantages over traditional methods for ceramide quantitation in that it determines the relative abundance of all ceramide species present in complex biological lipid mixtures individually and simultaneously. We quantitiated ceramides ranging from C14 to C26, finding that their basal levels and relative distribution varied significantly, both within and between different cell types. However, we were not able to detect any significant changes in either total ceramide content or species distribution until 1 h or more post-stimulation with any of these treatments, by which time the cells were in an advanced stage of apoptosis. Differences were also seen between all three treatments in the ceramide species distribution observed in these late stages of apoptosis. These data indicate that in vivo ceramide generation occurs as a consequence of apoptosis rather than as an essential second messenger involved in its induction. They also pose new questions about the potential roles that certain ceramide species may play in the late stages of apoptosis, and demonstrate a clear need to utilize the resolving power of mass spectrometry-based assays in any future investigations into the biological function of ceramides.  (+info)

Inhibition of GABA-gated chloride channels by 12,14-dichlorodehydroabietic acid in mammalian brain. (4/2175)

1. 12,14-dichlorodehydroabietic acid (12,14-Cl2DHA) reduced GABA-stimulated uptake of 36Cl- into mouse brain synaptoneurosomes suggesting inhibition of mammalian GABA(A) receptor function. 2. 12,14-Cl2DHA did not affect the binding of [3H]-muscimol to brain membranes but displaced specifically bound [3H]-EBOB. The inhibitory effect on [3H]-EBOB binding was not reversible. 12,14-Cl2DHA reduced the availability of [3H]-EBOB binding sites (Bmax) without changing the KD of the radioligand for remaining sites. 12,14-Cl2DHA did not affect the rate of association of [3H]-EBOB with its chloride channel receptor, but increased the initial rate of [3H]-EBOB dissociation. 3. 12,14-Cl2DHA enhanced the incidence of EPSCs when rapidly applied to cultured rat cortical neurones. Longer exposures produced block of IPSCs with marked increases in the frequency of EPSCs and min EPSCs. 12,14-Cl2DHA also irreversibly suppressed chloride currents evoked by pulses of exogenous GABA in these cells. 4. Ultimately, 12,14-Cl2DHA inhibited all synaptic traffic and action currents in current clamped cells indicating that, in contrast to picrotoxinin (which causes paroxysmal bursting), it is not fully selective for the GABA(A) receptor-chloride channel complex. 5. The depolarizing block seen with 12,14-Cl2DHA in amphotericin-perforated preparations implicates loss of Ca2+ buffering in the polarity change and this may account for inhibition of spontaneous action potentials. 6. Our investigation demonstrates that 12,14-Cl2DHA blocks GABA-dependent chloride entry in mammalian brain and operates as a non-competitive insurmountable GABA(A) antagonist. The mechanism likely involves either irreversible binding of 12,14-Cl2DHA to the trioxabicyclooctane recognition site or a site that is allosterically coupled to it. We cannot exclude, however, the possibility that 12,14-Cl2DHA causes localized proteolysis or more extensive conformational change within a critical subunit of the chloride channel.  (+info)

A non-pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors. (5/2175)

1. A [3H]-resiniferatoxin (RTX) binding assay utilizing rat spinal cord membranes was employed to identify novel vanilloids in a collection of natural products of fungal origin. Of the five active compounds found (scutigeral, acetyl-scutigeral, ovinal, neogrifolin, and methyl-neogrifolin), scutigeral (Ki=19 microM), isolated from the edible mushroom Albatrellus ovinus, was selected for further characterization. 2. Scutigeral induced a dose-dependent 45Ca uptake by rat dorsal root ganglion neurons with an EC50 of 1.6 microM, which was fully inhibited by the competitive vanilloid receptor antagonist capsazepine (IC50=5.2 microM). 3. [3H]-RTX binding isotherms were shifted by scutigeral (10-80 microM) in a competitive manner. The Schild plot of the data had a slope of 0.8 and gave an apparent Kd estimate for scutigeral of 32 microM. 4. Although in the above assays scutigeral mimicked capsaicin, it was not pungent on the human tongue up to a dose of 100 nmol per tongue, nor did it provoke protective wiping movements in the rat (up to 100 microM) upon intraocular instillation. 5. In accord with being non-pungent, scutigeral (5 microM) did not elicit a measurable inward current in isolated rat dorsal root ganglion neurons under voltage-clamp conditions. It did, however, reduce the proportion of neurons (from 61 to 15%) that responded to a subsequent capsaicin (1 microM) challenge. In these neurons, scutigeral both delayed (from 27 to 72 s) and diminished (from 5.0 to 1.9 nA) the maximal current evoked by capsaicin. 6. In conclusion, scutigeral and its congeners form a new chemical class of vanilloids, the triprenyl phenols. Scutigeral promises to be a novel chemical lead for the development of orally active, non-pungent vanilloids.  (+info)

A novel aromatic-ring-hydroxylating dioxygenase from the diterpenoid-degrading bacterium Pseudomonas abietaniphila BKME-9. (6/2175)

Pseudomonas abietaniphila BKME-9 is able to degrade dehydroabietic acid (DhA) via ring hydroxylation by a novel dioxygenase. The ditA1, ditA2, and ditA3 genes, which encode the alpha and beta subunits of the oxygenase and the ferredoxin of the diterpenoid dioxygenase, respectively, were isolated and sequenced. The ferredoxin gene is 9. 2 kb upstream of the oxygenase genes and 872 bp upstream of a putative meta ring cleavage dioxygenase gene, ditC. A Tn5 insertion in the alpha subunit gene, ditA1, resulted in the accumulation by the mutant strain BKME-941 of the pathway intermediate, 7-oxoDhA. Disruption of the ferredoxin gene, ditA3, in wild-type BKME-9 by mutant-allele exchange resulted in a strain (BKME-91) with a phenotype identical to that of the mutant strain BKME-941. Sequence analysis of the putative ferredoxin indicated that it is likely to be a [4Fe-4S]- or [3Fe-4S]-type ferredoxin and not a [2Fe-2S]-type ferredoxin, as found in all previously described ring-hydroxylating dioxygenases. Expression in Escherichia coli of ditA1A2A3, encoding the diterpenoid dioxygenase without its putative reductase component, resulted in a functional enzyme. The diterpenoid dioxygenase attacks 7-oxoDhA, and not DhA, at C-11 and C-12, producing 7-oxo-11, 12-dihydroxy-8,13-abietadien acid, which was identified by 1H nuclear magnetic resonance, UV-visible light, and high-resolution mass spectrometry. The organization of the genes encoding the various components of the diterpenoid dioxygenase, the phylogenetic distinctiveness of both the alpha subunit and the ferredoxin component, and the unusual Fe-S cluster of the ferredoxin all suggest that this enzyme belongs to a new class of aromatic ring-hydroxylating dioxygenases.  (+info)

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation. (7/2175)

PG490 (triptolide) is a diterpene triepoxide with potent immunosuppressive and antiinflammatory properties. PG490 inhibits interleukin(IL)-2 expression by normal human peripheral blood lymphocytes stimulated with phorbol 12-myristate 13-acetate (PMA) and antibody to CD3 (IC50 of 10 ng/ml), and with PMA and ionomycin (Iono, IC50 of 40 ng/ml). In Jurkat T-cells, PG490 inhibits PMA/Iono-stimulated IL-2 transcription. PG490 inhibits the induction of DNA binding activity at the purine-box/antigen receptor response element (ARRE)/nuclear factor of activated T-cells (NF-AT) target sequence but not at the NF-kappaB site. PG490 can completely inhibit transcriptional activation at the purine-box/ARRE/NF-AT and NF-kappaB target DNA sequences triggered by all stimuli examined (PMA, PMA/Iono, tumor necrosis factor-alpha). PG490 also inhibits PMA-stimulated activation of a chimeric transcription factor in which the C-terminal TA1 transactivation domain of NF-kappaB p65 is fused to the DNA binding domain of GAL4. In 16HBE human bronchial epithelial cells, IL-8 expression is regulated predominantly by NF-kappaB, and PG490 but not cyclosporin A can completely inhibit expression of IL-8. The mechanism of PG490 inhibition of cytokine gene expression differs from cyclosporin A and involves nuclear inhibition of transcriptional activation of NF-kappaB and the purine-box regulator operating at the ARRE/NF-AT site at a step after specific DNA binding.  (+info)

PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. (8/2175)

Progress in the treatment of solid tumors has been slow and sporadic. The efficacy of conventional chemotherapy in solid tumors is limited because tumors frequently have mutations in the p53 gene. Also, chemotherapy only kills rapidly dividing cells. Members of the tumor necrosis factor (TNF) family, however, induce apoptosis regardless of the p53 phenotype. Unfortunately, the cytotoxicity of TNF-alpha is limited by its activation of NF-kappaB and activation of NF-kappaB is proinflammatory. We have identified a compound called PG490, that is composed of purified triptolide, which induces apoptosis in tumor cells and sensitizes tumor cells to TNF-alpha-induced apoptosis. PG490 potently inhibited TNF-alpha-induced activation of NF-kappaB. PG490 also blocked TNF-alpha-mediated induction of c-IAP2 (hiap-1) and c-IAP1 (hiap-2), members of the inhibitor of apoptosis (IAP) family. Interestingly, PG490 did not block DNA binding of NF-kappaB, but it blocked transactivation of NF-kappaB. Our identification of a compound that blocks TNF-alpha-induced activation of NF-kappaB may enhance the cytotoxicity of TNF-alpha on tumors in vivo and limit its proinflammatory effects.  (+info)

Diterpenes are a class of naturally occurring compounds that are composed of four isoprene units, which is a type of hydrocarbon. They are synthesized by a wide variety of plants and animals, and are found in many different types of organisms, including fungi, insects, and marine organisms.

Diterpenes have a variety of biological activities and are used in medicine for their therapeutic effects. Some diterpenes have anti-inflammatory, antimicrobial, and antiviral properties, and are used to treat a range of conditions, including respiratory infections, skin disorders, and cancer.

Diterpenes can be further classified into different subgroups based on their chemical structure and biological activity. Some examples of diterpenes include the phytocannabinoids found in cannabis plants, such as THC and CBD, and the paclitaxel, a diterpene found in the bark of the Pacific yew tree that is used to treat cancer.

It's important to note that while some diterpenes have therapeutic potential, others may be toxic or have adverse effects, so it is essential to use them under the guidance and supervision of a healthcare professional.

Abietanes are a subclass of diterpenes, which are a type of organic compound consisting of four isoprene units and having the chemical formula C20H32. Diterpenes are synthesized by a wide variety of plants and some animals, and they have diverse biological activities.

Abietanes are characterized by a distinctive carbon skeleton that contains three six-membered rings arranged in a linear fashion, with the fourth ring being a five-membered ring. This particular structure is derived from geranylgeranyl pyrophosphate (GGPP), a precursor to many diterpenes.

Abietanes are found in various natural sources, including pine resin, where they exist as resin acids such as abietic acid, pimaric acid, and isopimaric acid. These compounds have been studied for their potential medicinal properties, including anti-inflammatory, antimicrobial, and anticancer activities. However, more research is needed to fully understand the therapeutic potential of abietanes and to develop safe and effective treatments based on these compounds.

Clerodane diterpenes are a type of diterpene, which is a class of naturally occurring organic compounds that contain 20 carbon atoms arranged in a particular structure. Diterpenes are synthesized by a variety of plants and some animals, and they have diverse biological activities.

Clerodane diterpenes are named after the plant genus Clerodendron, which contains many species that produce these compounds. These compounds have a characteristic carbon skeleton known as the clerodane skeleton, which is characterized by a bridged bicyclic structure.

Clerodane diterpenes have been studied for their potential medicinal properties, including anti-inflammatory, antimicrobial, and anticancer activities. Some clerodane diterpenes have been found to inhibit the growth of certain types of cancer cells, while others have been shown to have immunomodulatory effects. However, more research is needed to fully understand their mechanisms of action and potential therapeutic uses.

Diterpenes, kaurane refers to a class of diterpenoids with a unique chemical structure called a kaurane skeleton. Diterpenes are a type of terpene, which are natural compounds derived from isoprene units. Kaurane diterpenes are characterized by a particular carbon skeleton consisting of five six-membered rings, including four cyclohexane rings and one cyclopentane ring.

Kaurane diterpenes can be found in various plants, including those used in traditional medicine. Some kaurane diterpenes have been reported to possess biological activities, such as anti-inflammatory, antiviral, and cytotoxic effects. However, more research is needed to fully understand their therapeutic potential and safety profile.

Euphorbia is a genus of plants that belongs to the spurge family (Euphorbiaceae). It contains around 2,000 species of shrubs, trees, and herbs that are found worldwide, particularly in tropical and subtropical regions. Many euphorbias are known for their milky sap, which can be toxic or irritating to the skin and mucous membranes. Some species of euphorbia are cultivated as ornamental plants due to their attractive flowers and foliage, while others have medicinal or industrial uses. However, it's important to note that some euphorbias can be invasive and harmful to local ecosystems, so care should be taken when handling or growing them.

'Caesalpinia' is a genus of flowering plants in the pea family, Fabaceae. It includes several species that are native to tropical and subtropical regions around the world. Some common names for plants in this genus include poison ivy, pencil cactus, and Brazilian rosewood.

Many species of Caesalpinia contain toxic compounds and can cause skin irritation or other adverse health effects if ingested or come into contact with the skin. For example, the sap of some species can cause a rash similar to poison ivy. It is important to use caution when handling these plants and to seek medical attention if you experience any symptoms after coming into contact with them.

It is worth noting that 'Caesalpinia' is a taxonomic category used in the classification of plants, and it does not have a specific medical definition. If you are looking for information about a specific medical condition or treatment, I would recommend consulting a healthcare professional or searching for information from a reputable medical source.

"Salvia" is a genus of plants that includes over 900 species, with some commonly known as sage. However, in a medical context, the term "Salvia" often refers to Salvia divinorum, a specific species of this plant. Salvia divinorum, also known as sage of the diviners, is a psychoactive herb that can produce hallucinations and other altered mental states when ingested, usually by smoking or chewing the leaves. It contains a chemical called salvinorin A, which is believed to be responsible for its psychoactive effects.

It's important to note that while Salvia divinorum has been used in traditional healing practices in some cultures, it can also have dangerous side effects and its use is regulated in many parts of the world. It should only be used under medical supervision and with a clear understanding of its potential risks.

I apologize for any confusion, but "Verbenaceae" is not a medical term. It is a taxonomic category in botany, referring to the Verbena family of plants, which includes various species of trees, shrubs, and herbs. Some members of this family have been used in traditional medicine, but "Verbenaceae" itself does not have a specific medical definition.

Chamaecyparis is a genus of evergreen coniferous trees in the family Cupressaceae. It includes several species commonly known as cypress or false cypress, which are native to eastern Asia and North America. These trees are characterized by their flattened sprays of scale-like leaves, small cones, and distinctive bark patterns. They are often grown as ornamental plants due to their attractive appearance and ability to thrive in a variety of climates.

There is no specific medical definition associated with Chamaecyparis, as it is not a term used in medicine. However, some compounds derived from these trees have been studied for their potential medicinal properties. For example, certain essential oils extracted from Chamaecyparis species have been found to have antimicrobial and insecticidal effects, although more research is needed to determine their safety and efficacy as treatments for human diseases.

'Cistus' is a term that refers to a genus of plants commonly known as rockroses. These plants are native to the Mediterranean region and have pink, white, or red flowers. They belong to the family Cistaceae. While 'Cistus' is a plant genus and not a medical term, extracts from some species of Cistus have been used in traditional medicine for various purposes, such as treating skin conditions and wounds. However, it is important to note that the medical efficacy and safety of these uses have not been thoroughly studied or proven by modern scientific research.

Cupressaceae is a family of coniferous plants, also known as the cypress family. It includes a variety of genera such as *Cupressus* (cypress), *Juniperus* (juniper), *Thuja* (arborvitae or cedar), and *Chamaecyparis* (false cypress or Port Orford cedar). These plants are characterized by their small, scale-like leaves, and many produce cones that contain seeds. Some species in this family have economic importance as timber, ornamental plants, or for their essential oils.

I'm sorry for any confusion, but "Plant Bark" is not a term with a specific medical definition. In general, the bark refers to the outermost covering of a tree or other plant, which serves as protection and provides a barrier against external threats. It is composed of layers including the inner bark (phloem), which transports nutrients throughout the plant, and the outer bark (periderm), which is made up of dead cells that form a protective layer.

While some plants or plant parts do have medicinal properties and are used in various forms of traditional or alternative medicine, "Plant Bark" by itself does not have any specific medical connotations. If you're referring to a specific type of plant bark with potential medicinal uses, please provide more details so I can give a more accurate response.

Orthosiphon is a genus of plants in the family Lamiaceae, also known as the mint or deadnettle family. The most common species is Orthosiphon stamineus, also known as Cat's Whiskers or Java Tea. This plant is native to Southeast Asia and some parts of Australia.

In a medical context, Orthosiphon stamineus is used in traditional medicine for its diuretic, antioxidant, anti-inflammatory, and antibacterial properties. The leaves and stems of the plant are dried and prepared as an herbal infusion or decoction to treat various health conditions such as kidney stones, urinary tract infections, and high blood pressure. However, it is important to note that the scientific evidence supporting these claims is limited, and more research is needed to establish its safety and efficacy.

"Polyalthia" is a genus of flowering plants in the family Annonaceae, which is known for its tropical trees and shrubs. It's not a medical term, but a taxonomic category used in the classification of plants. The plants in this genus are native to Southeast Asia, Australia, and Pacific islands. They typically produce large, fleshy fruits that contain numerous seeds. Some species of Polyalthia have been used in traditional medicine in various cultures, although more research is needed to confirm their medicinal properties and safety.

Thymelaeaceae is not a medical term, but a taxonomic category in botany. It refers to a family of flowering plants that includes around 50 genera and about 800 species. Some members of this family have been used in traditional medicine, but it's important to note that the use of specific plant species for medicinal purposes should be under the guidance of healthcare professionals, as they can provide information on safe usage, potential interactions with other medications, and appropriate dosages.

I'm sorry for any confusion, but "Mikania" is not a medical term. It is actually the name of a genus of plants in the family Asteraceae, also known as the daisy family. The most well-known species is Mikania micrantha, which is native to Central and South America but has become an invasive weed in many other parts of the world, including Southeast Asia, Africa, and the Pacific Islands. It is often referred to by the common name "climbing hempvine" or "mile-a-minute weed."

If you have any questions related to medical terminology or health concerns, I'd be happy to try to help answer those for you!

A plant extract is a preparation containing chemical constituents that have been extracted from a plant using a solvent. The resulting extract may contain a single compound or a mixture of several compounds, depending on the extraction process and the specific plant material used. These extracts are often used in various industries including pharmaceuticals, nutraceuticals, cosmetics, and food and beverage, due to their potential therapeutic or beneficial properties. The composition of plant extracts can vary widely, and it is important to ensure their quality, safety, and efficacy before use in any application.

Molecular structure, in the context of biochemistry and molecular biology, refers to the arrangement and organization of atoms and chemical bonds within a molecule. It describes the three-dimensional layout of the constituent elements, including their spatial relationships, bond lengths, and angles. Understanding molecular structure is crucial for elucidating the functions and reactivities of biological macromolecules such as proteins, nucleic acids, lipids, and carbohydrates. Various experimental techniques, like X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy (cryo-EM), are employed to determine molecular structures at atomic resolution, providing valuable insights into their biological roles and potential therapeutic targets.

Aerial parts of plants refer to the above-ground portions of a plant, including leaves, stems, flowers, and fruits. These parts are often used in medicine, either in their entirety or as isolated extracts, to take advantage of their medicinal properties. The specific components of aerial parts that are used in medicine can vary depending on the plant species and the desired therapeutic effects. For example, the leaves of some plants may contain active compounds that have anti-inflammatory or analgesic properties, while the flowers of others may be rich in antioxidants or compounds with sedative effects. In general, aerial parts of plants are used in herbal medicine to treat a wide range of conditions, including respiratory, digestive, and nervous system disorders, as well as skin conditions and infections.

"Thuja" is a botanical term for a genus of evergreen trees and shrubs, also known as arborvitae or western red cedar. It belongs to the family Cupressaceae. While it has some traditional medicinal uses, there isn't a widely accepted medical definition for "Thuja" in modern medicine.

Historically, preparations made from Thuja occidentalis (eastern white cedar) have been used in alternative and traditional medicine, such as homeopathy. The leaves and twigs are often used to make teas, tinctures, or essential oils. However, it's important to note that the use of Thuja for medicinal purposes can have potential side effects and toxicities, and its effectiveness is not always supported by scientific evidence. Always consult with a healthcare provider before starting any new treatment.

Anthozoa is a major class of marine animals, which are exclusively aquatic and almost entirely restricted to shallow waters. They are classified within the phylum Cnidaria, which also includes corals, jellyfish, sea anemones, and hydroids. Anthozoans are characterized by their lack of medusa stage in their life cycle, as they exist solely as polyps.

This class is divided into two main subclasses: Hexacorallia (also known as Zoantharia) and Octocorallia (also known as Alcyonaria). The primary differences between these subclasses lie in the structure of their polyps and the composition of their skeletons.

1. Hexacorallia: These are commonly referred to as 'stony' or 'hard' corals, due to their calcium carbonate-based skeletons. They have a simple polyp structure with six-fold symmetry (hence the name Hexacorallia), featuring 6 tentacles around the mouth opening. Examples of Hexacorallia include reef-building corals, sea fans, and black corals.
2. Octocorallia: These are also called 'soft' corals or 'leather' corals because they lack a calcium carbonate skeleton. Instead, their supporting structures consist of proteins and other organic compounds. Octocorallia polyps exhibit eight-fold symmetry (hence the name Octocorallia), with eight tentacles around the mouth opening. Examples of Octocorallia include sea fans, sea whips, and blue corals.

Anthozoa species are primarily found in tropical and subtropical oceans, but some can be found in colder, deeper waters as well. They play a crucial role in marine ecosystems by providing habitats and shelter for various other marine organisms, particularly on coral reefs. Additionally, they contribute to the formation of limestone deposits through their calcium carbonate-based skeletons.

"Cryptomeria" is not a term commonly used in medical definitions. It is actually the scientific name for a type of evergreen tree, also known as Japanese cedar. In some cases, Cryptomeria pollen may cause allergic reactions in susceptible individuals, leading to symptoms such as sneezing, runny nose, and itchy eyes. However, it is not a medical condition itself.

"Viburnum" is not a medical term, but a genus of shrubs and small trees that belong to the Adoxaceae family. These plants are commonly known as "viburnums," and they have various uses in horticulture due to their attractive flowers, fruits, and foliage.

While there may be some medicinal uses for certain species of Viburnum, it is not a term that would typically appear in a medical context or definition. If you're looking for information about the medicinal properties of specific plants within the Viburnum genus, I would recommend consulting a reliable source on herbal medicine or speaking with a healthcare professional who has expertise in this area.

Sesquiterpenes are a class of terpenes, which are large and diverse group of naturally occurring organic compounds derived from isoprene, a five-carbon molecule. Sesquiterpenes are composed of three isoprene units, making them 15-carbon structures. They are synthesized in plants, fungi, and some insects, and can be found in various essential oils, resins, and other natural products.

Guaiane is a subclass of sesquiterpenes characterized by a particular carbon skeleton structure. Guaiane-type sesquiterpenes contain a unique bicyclic ring system with a five-membered ring fused to a seven-membered ring. This class of compounds includes various natural products, some of which have been found to exhibit biological activities, such as anti-inflammatory, antimicrobial, and cytotoxic effects.

Examples of guaiane sesquiterpenes include:

1. Guaiol: A compound found in the wood of the guaiacum tree, it has been used in traditional medicine for its anti-inflammatory properties.
2. Bulnesin: A compound isolated from the bulnesia sarmientoi tree, it has shown potential as an anticancer agent.
3. Elephantopusin: A compound found in elephantopus mollis, it has been studied for its anti-inflammatory and antioxidant properties.

It is important to note that while these compounds have demonstrated biological activities, further research is necessary to fully understand their mechanisms of action and potential therapeutic applications.

"Casearia" is a genus of flowering plants in the family Salicaceae, which includes around 150-200 species. These plants are commonly known as shrubs or small trees and are native to tropical and subtropical regions around the world. The leaves of Casearia plants are typically simple and opposite, with serrated or entire margins. The flowers are small and greenish-white, and the fruit is a drupe that contains one or two seeds.

Some species of Casearia have been used in traditional medicine to treat various ailments, such as skin conditions, fever, and diarrhea. However, it's important to note that the safety and efficacy of using these plants for medicinal purposes have not been thoroughly studied or proven through scientific research. Therefore, it is not recommended to use any plant or herbal remedy without consulting a qualified healthcare professional first.

I'm sorry for any confusion, but the term "Scoparia" is not a recognized medical term in human or veterinary medicine. It is most likely a botanical name, as Scoparia is a genus of flowering plants in the family Plantaginaceae. If you have a specific medical context in which this term was used, I would be happy to help further if I can.

Terpenes are a large and diverse class of organic compounds produced by a variety of plants, including cannabis. They are responsible for the distinctive aromas and flavors found in different strains of cannabis. Terpenes have been found to have various therapeutic benefits, such as anti-inflammatory, analgesic, and antimicrobial properties. Some terpenes may also enhance the psychoactive effects of THC, the main psychoactive compound in cannabis. It's important to note that more research is needed to fully understand the potential medical benefits and risks associated with terpenes.

Magnetic Resonance Spectroscopy (MRS) is a non-invasive diagnostic technique that provides information about the biochemical composition of tissues, including their metabolic state. It is often used in conjunction with Magnetic Resonance Imaging (MRI) to analyze various metabolites within body tissues, such as the brain, heart, liver, and muscles.

During MRS, a strong magnetic field, radio waves, and a computer are used to produce detailed images and data about the concentration of specific metabolites in the targeted tissue or organ. This technique can help detect abnormalities related to energy metabolism, neurotransmitter levels, pH balance, and other biochemical processes, which can be useful for diagnosing and monitoring various medical conditions, including cancer, neurological disorders, and metabolic diseases.

There are different types of MRS, such as Proton (^1^H) MRS, Phosphorus-31 (^31^P) MRS, and Carbon-13 (^13^C) MRS, each focusing on specific elements or metabolites within the body. The choice of MRS technique depends on the clinical question being addressed and the type of information needed for diagnosis or monitoring purposes.

'Salvia officinalis', also known as garden sage or common sage, is not a medical condition but an herb that has been used in traditional medicine. Here's the botanical definition:

Salvia officinalis, commonly known as sage, garden sage, or common sage, is a perennial, evergreen subshrub, with woody stems, grayish leaves, and blue to purplish flowers. It belongs to the Lamiaceae family, also known as the mint family. The plant is native to the Mediterranean region and has been cultivated throughout the world for its aromatic leaves, which are used in cooking, cosmetics, and medicinal preparations.

In traditional medicine, sage leaves have been used to treat various conditions, such as sore throats, coughs, colds, and digestive issues. However, it is essential to note that the effectiveness of sage for these uses has not been thoroughly studied in clinical trials, and its use should not replace conventional medical care. Always consult with a healthcare professional before starting any new treatment or therapy.

Menispermaceae is not a medical term, but a botanical term referring to a family of flowering plants. It includes around 70 genera and 450-550 species of woody vines, shrubs, and small trees. Some members of this family contain alkaloids and have been used in traditional medicine in various parts of the world. However, it is important to note that the use of these plants as medicine should be done under the guidance of a healthcare professional, as they can also contain toxic compounds.

Medicinal plants are defined as those plants that contain naturally occurring chemical compounds which can be used for therapeutic purposes, either directly or indirectly. These plants have been used for centuries in various traditional systems of medicine, such as Ayurveda, Chinese medicine, and Native American medicine, to prevent or treat various health conditions.

Medicinal plants contain a wide variety of bioactive compounds, including alkaloids, flavonoids, tannins, terpenes, and saponins, among others. These compounds have been found to possess various pharmacological properties, such as anti-inflammatory, analgesic, antimicrobial, antioxidant, and anticancer activities.

Medicinal plants can be used in various forms, including whole plant material, extracts, essential oils, and isolated compounds. They can be administered through different routes, such as oral, topical, or respiratory, depending on the desired therapeutic effect.

It is important to note that while medicinal plants have been used safely and effectively for centuries, they should be used with caution and under the guidance of a healthcare professional. Some medicinal plants can interact with prescription medications or have adverse effects if used inappropriately.

In a medical context, "resins, plant" refer to the sticky, often aromatic substances produced by certain plants. These resins are typically composed of a mixture of volatile oils, terpenes, and rosin acids. They may be present in various parts of the plant, including leaves, stems, and roots, and are often found in specialized structures such as glands or ducts.

Plant resins have been used for centuries in traditional medicine and other applications. Some resins have antimicrobial, anti-inflammatory, or analgesic properties and have been used to treat a variety of ailments, including skin conditions, respiratory infections, and pain.

Examples of plant resins with medicinal uses include:

* Frankincense (Boswellia spp.) resin has been used in traditional medicine to treat inflammation, arthritis, and asthma.
* Myrrh (Commiphora spp.) resin has been used as an antiseptic, astringent, and anti-inflammatory agent.
* Pine resin has been used topically for its antimicrobial and anti-inflammatory properties.

It's important to note that while some plant resins have demonstrated medicinal benefits, they should be used with caution and under the guidance of a healthcare professional. Some resins can have adverse effects or interact with medications, and it's essential to ensure their safe and effective use.

Scrophulariaceae is a family of plants commonly known as the Figwort or Snapdragon family. It was once a large and diverse group, but many of its members have been reclassified into different families in recent years based on molecular evidence. The family still includes a number of well-known garden plants such as foxgloves (Digitalis), snapdragons (Antirrhinum), and penstemons (Penstemon).

The plants in Scrophulariaceae are typically herbaceous, although some are shrubs or small trees. They are characterized by their two-lipped flowers, with the upper lip usually forming a hood and the lower lip often having three lobes. The stamens and style are often enclosed within the flower and only emerge when it is fully open.

Scrophulariaceae has been reported to contain various chemical compounds with potential medicinal properties, such as cardiac glycosides in Digitalis species, which have been used to treat heart conditions. However, it's important to note that the use of these plants for medicinal purposes should only be done under the guidance and supervision of a qualified healthcare professional, as they can also contain toxic compounds that may cause harm if not used correctly.

Phaeophyta is a taxonomic division that refers to a group of complex, multicellular brown algae found in marine environments. These algae are characterized by their pigmentation, which includes fucoxanthin, chlorophyll-a, and chlorophyll-c, giving them a brown color. They have diverse morphology, ranging from simple thread-like forms to large seaweeds.

Phaeophyta species are primarily found in cold, nutrient-rich waters and play an essential role in marine ecosystems as primary producers and habitats for various marine organisms. Some examples of Phaeophyta include kelps, rockweed, and bladderwrack. It's worth noting that the classification and nomenclature of algae are continually evolving, so different sources might use slightly different terminology or categorization.

"Fritillaria" is a genus of plants that includes around 140 species, many of which have been used in traditional medicine for various purposes. In a medical context, "Fritillaria" usually refers to the bulbs of certain Fritillaria species, such as Fritillaria cirrhosa and Fritillaria thunbergii, which are used in Traditional Chinese Medicine (TCM).

In TCM, Fritillaria bulbs are known as "Beimu" or "Chuanbei," and they have been used to treat respiratory conditions such as coughs, bronchitis, and asthma. The active components of Fritillaria include alkaloids, steroidal saponins, and polysaccharides, which are believed to have anti-inflammatory, expectorant, and antitussive effects.

However, it's important to note that the use of Fritillaria in medicine is not well-studied in Western medicine, and its effectiveness and safety are not established. Moreover, some Fritillaria species contain toxic compounds, so it's essential to consult a healthcare professional before using any Fritillaria products for medicinal purposes.

I'm sorry for any confusion, but "Paraguay" is not a medical term. It is the name of a country located in the central part of South America, bordered by Argentina to the south and southwest, Bolivia to the north and west, and Brazil to the east and northeast. If you have any questions related to medical terminology or health-related topics, I would be happy to try to help answer them for you.

Vitex, also known as chasteberry or Vitex agnus-castus, is not a medical term but a common herbal supplement. It is derived from the fruit of the Vitex agnus-castus tree, which is native to the Mediterranean region and parts of Asia.

The medical community has studied Vitex for its potential effects on various conditions, including premenstrual syndrome (PMS), menopausal symptoms, and irregular menstrual cycles. However, it's essential to note that the evidence supporting its use is mixed, and more research is needed to confirm its effectiveness and safety.

Vitex is thought to have dopamine-like effects on the hypothalamus, which may help regulate hormonal imbalances in some women. However, it can interact with other medications and has potential side effects, so it's crucial to consult a healthcare provider before taking Vitex or any herbal supplement.

I'm sorry for any confusion, but "Hepatophyta" is not a valid medical or scientific term in modern usage. It appears to be a combination of the Greek word "hepar" meaning "liver" and the suffix "-phyta" which is used to denote a plant or group of plants in taxonomy. However, it is not a term that is recognized or used in modern biology or medicine.

It's possible that you may be thinking of "Hepatica," which is a genus of flowering plants in the family Ranunculaceae. These plants are also known as liverworts, although they should not be confused with actual liverworts, which are non-vascular plants in the division Marchantiophyta.

If you have any further questions or if there is another term you would like me to define, please let me know!

"Larix" is not a medical term. It is the genus name for a group of trees commonly known as larches, which belong to the family Pinaceae. These deciduous conifers are native to the cooler temperate regions of the Northern Hemisphere. They are known for their needle-like leaves and cone-bearing fruits.

While not directly related to human health or medicine, certain compounds derived from plants in the Larix genus have been studied for potential medicinal properties. For example, extracts from larch bark have been investigated for their anti-inflammatory, antioxidant, and wound-healing effects. However, it is important to note that these studies are still in the preliminary stages, and more research is needed before any definitive conclusions can be drawn about the medicinal applications of Larix species.

"Aristolochia" is a genus of flowering plants in the family Aristolochiaceae, also known as birthworts. These plants are characterized by their unique, pipe-shaped flowers. Some species of Aristolochia contain aristolochic acids, which have been found to be nephrotoxic and carcinogenic. Because of this, the use of these plants in medicinal preparations is generally discouraged or restricted.

Molecular conformation, also known as spatial arrangement or configuration, refers to the specific three-dimensional shape and orientation of atoms that make up a molecule. It describes the precise manner in which bonds between atoms are arranged around a molecular framework, taking into account factors such as bond lengths, bond angles, and torsional angles.

Conformational isomers, or conformers, are different spatial arrangements of the same molecule that can interconvert without breaking chemical bonds. These isomers may have varying energies, stability, and reactivity, which can significantly impact a molecule's biological activity and function. Understanding molecular conformation is crucial in fields such as drug design, where small changes in conformation can lead to substantial differences in how a drug interacts with its target.

"Rosmarinus" is the genus name for rosemary, a woody herb that belongs to the mint family (Lamiaceae). The most common species is Rosmarinus officinalis. It is native to the Mediterranean region and is widely used in cooking, cosmetics, and traditional medicine. In a medical context, "Rosmarinus" would refer to the medicinal properties or uses of the rosemary plant.

Asteraceae is a family of flowering plants commonly known as the daisy family or sunflower family. It is one of the largest and most diverse families of vascular plants, with over 1,900 genera and 32,000 species. The family includes a wide variety of plants, ranging from annual and perennial herbs to shrubs and trees.

The defining characteristic of Asteraceae is the presence of a unique type of inflorescence called a capitulum, which resembles a single flower but is actually composed of many small flowers (florets) arranged in a dense head. The florets are typically bisexual, with both male and female reproductive structures, and are radially symmetrical.

Asteraceae includes many economically important plants, such as sunflowers, daisies, artichokes, lettuce, chicory, and ragweed. Some species of Asteraceae are also used in traditional medicine and have been found to contain bioactive compounds with potential therapeutic uses.

It's worth noting that the taxonomy of this family has undergone significant revisions in recent years, and some genera and species have been moved to other families or renamed.

Fast Atom Bombardment (FAB) Mass Spectrometry is a technique used for determining the mass of ions in a sample. In FAB-MS, the sample is mixed with a matrix material and then bombarded with a beam of fast atoms, usually xenon or cesium. This bombardment leads to the formation of ions from the sample which can then be detected and measured using a mass analyzer. The resulting mass spectrum provides information about the molecular weight and structure of the sample molecules. FAB-MS is particularly useful for the analysis of large, thermally labile, or polar molecules that may not ionize well by other methods.

The term "Croton" is most commonly used to refer to a genus of flowering plants in the spurge family (Euphorbiaceae), which includes over 700 species. These plants are native to tropical and subtropical regions around the world, with many having colorful and distinctive leaves or flowers.

However, "Croton" is not a medical term and does not have a specific definition in the context of medicine. If you have any questions about a medical condition or treatment that involves the use of the term "Croton," it would be best to consult with a healthcare professional for clarification.

Coffee is defined in medical terms as a beverage prepared from the roasted seeds of the Coffea plant. It contains caffeine, a stimulant that can help increase alertness, improve mood, and boost mental and physical performance. Coffee also contains antioxidants and other bioactive compounds that may have health benefits. However, excessive consumption of coffee can lead to side effects such as insomnia, nervousness, restlessness, and rapid heart rate. It's important to consume coffee in moderation and be aware of its potential interactions with medications and medical conditions.

Spectrophotometry, Infrared is a scientific analytical technique used to measure the absorption or transmission of infrared light by a sample. It involves the use of an infrared spectrophotometer, which directs infrared radiation through a sample and measures the intensity of the radiation that is transmitted or absorbed by the sample at different wavelengths within the infrared region of the electromagnetic spectrum.

Infrared spectroscopy can be used to identify and quantify functional groups and chemical bonds present in a sample, as well as to study the molecular structure and composition of materials. The resulting infrared spectrum provides a unique "fingerprint" of the sample, which can be compared with reference spectra to aid in identification and characterization.

Infrared spectrophotometry is widely used in various fields such as chemistry, biology, pharmaceuticals, forensics, and materials science for qualitative and quantitative analysis of samples.

I'm sorry for any confusion, but "Wood" is not a medical term. It is a common name for various hard, fibrous tissues that make up the trunks and branches of trees and shrubs, as well as a term used for a wide range of items made from these materials. If you have any medical concerns or questions, I would be happy to try and help answer those for you.

Sesquiterpenes are a class of terpenes that consist of three isoprene units, hence the name "sesqui-" meaning "one and a half" in Latin. They are composed of 15 carbon atoms and have a wide range of chemical structures and biological activities. Sesquiterpenes can be found in various plants, fungi, and insects, and they play important roles in the defense mechanisms of these organisms. Some sesquiterpenes are also used in traditional medicine and have been studied for their potential therapeutic benefits.

I believe there may be a slight misunderstanding in your question. "Plant leaves" are not a medical term, but rather a general biological term referring to a specific organ found in plants.

Leaves are organs that are typically flat and broad, and they are the primary site of photosynthesis in most plants. They are usually green due to the presence of chlorophyll, which is essential for capturing sunlight and converting it into chemical energy through photosynthesis.

While leaves do not have a direct medical definition, understanding their structure and function can be important in various medical fields, such as pharmacognosy (the study of medicinal plants) or environmental health. For example, certain plant leaves may contain bioactive compounds that have therapeutic potential, while others may produce allergens or toxins that can impact human health.

I'm sorry for any confusion, but "Indonesia" is not a medical term. It is a country located in Southeast Asia and Oceania, between the Indian and Pacific oceans. It is the world's largest island country, with more than thirteen thousand islands. If you have any questions about medical terms or concepts, I would be happy to help with those!

Phenanthrenes are not typically defined in a medical context, but they are a class of organic compounds that have a polycyclic aromatic hydrocarbon structure consisting of three benzene rings fused together. They can be found in some natural products and have been studied for their potential pharmacological properties. Some phenanthrenes have shown anti-inflammatory, antioxidant, and cytotoxic activities, among others. However, more research is needed to fully understand their therapeutic potential and safety profile.

Stereoisomerism is a type of isomerism (structural arrangement of atoms) in which molecules have the same molecular formula and sequence of bonded atoms, but differ in the three-dimensional orientation of their atoms in space. This occurs when the molecule contains asymmetric carbon atoms or other rigid structures that prevent free rotation, leading to distinct spatial arrangements of groups of atoms around a central point. Stereoisomers can have different chemical and physical properties, such as optical activity, boiling points, and reactivities, due to differences in their shape and the way they interact with other molecules.

There are two main types of stereoisomerism: enantiomers (mirror-image isomers) and diastereomers (non-mirror-image isomers). Enantiomers are pairs of stereoisomers that are mirror images of each other, but cannot be superimposed on one another. Diastereomers, on the other hand, are non-mirror-image stereoisomers that have different physical and chemical properties.

Stereoisomerism is an important concept in chemistry and biology, as it can affect the biological activity of molecules, such as drugs and natural products. For example, some enantiomers of a drug may be active, while others are inactive or even toxic. Therefore, understanding stereoisomerism is crucial for designing and synthesizing effective and safe drugs.

A plant stem is not typically defined in a medical context, but rather in the field of botany. However, I can certainly provide a general biological definition for you.

In plants, stems are organs that serve primarily as support structures, holding leaves, flowers, and fruits aloft where they can receive sunlight and exchange gases. They also act as conduits, transporting water, nutrients, and sugars made during photosynthesis between the roots and shoots of a plant.

The stem is usually composed of three main tissue systems: dermal, vascular, and ground. The dermal tissue system forms the outermost layer(s) of the stem, providing protection and sometimes participating in gas exchange. The vascular tissue system contains the xylem (which transports water and nutrients upward) and phloem (which transports sugars and other organic compounds downward). The ground tissue system, located between the dermal and vascular tissues, is responsible for food storage and support.

While not a direct medical definition, understanding the structure and function of plant stems can be relevant in fields such as nutrition, agriculture, and environmental science, which have implications for human health.

Drug screening assays for antitumor agents are laboratory tests used to identify and evaluate the effectiveness of potential drugs or compounds that can inhibit the growth of tumor cells or induce their death. These assays are typically performed in vitro (in a test tube or petri dish) using cell cultures of various types of cancer cells.

The assays measure different parameters such as cell viability, proliferation, apoptosis (programmed cell death), and cytotoxicity to determine the ability of the drug to kill or inhibit the growth of tumor cells. The results of these assays can help researchers identify promising antitumor agents that can be further developed for clinical use in cancer treatment.

There are different types of drug screening assays for antitumor agents, including high-throughput screening (HTS) assays, which allow for the rapid and automated testing of a large number of compounds against various cancer cell lines. Other types of assays include phenotypic screening assays, target-based screening assays, and functional screening assays, each with its own advantages and limitations.

Overall, drug screening assays for antitumor agents play a critical role in the development of new cancer therapies by providing valuable information on the activity and safety of potential drugs, helping to identify effective treatments and reduce the time and cost associated with bringing new drugs to market.

Cyclization is a chemical process that involves forming a cyclic structure or ring-shaped molecule from a linear or open-chain compound. In the context of medicinal chemistry and drug design, cyclization reactions are often used to synthesize complex molecules, including drugs, by creating rings or fused ring systems within the molecule's structure.

Cyclization can occur through various mechanisms, such as intramolecular nucleophilic substitution, electrophilic addition, or radical reactions. The resulting cyclized compounds may exhibit different chemical and biological properties compared to their linear precursors, making them valuable targets for drug discovery and development.

In some cases, the cyclization process can lead to the formation of stereocenters within the molecule, which can impact its three-dimensional shape and how it interacts with biological targets. Therefore, controlling the stereochemistry during cyclization reactions is crucial in medicinal chemistry to optimize the desired biological activity.

Overall, cyclization plays a significant role in the design and synthesis of many pharmaceutical compounds, enabling the creation of complex structures that can interact specifically with biological targets for therapeutic purposes.

Glycosides are organic compounds that consist of a glycone (a sugar component) linked to a non-sugar component, known as an aglycone, via a glycosidic bond. They can be found in various plants, microorganisms, and some animals. Depending on the nature of the aglycone, glycosides can be classified into different types, such as anthraquinone glycosides, cardiac glycosides, and saponin glycosides.

These compounds have diverse biological activities and pharmacological effects. For instance:

* Cardiac glycosides, like digoxin and digitoxin, are used in the treatment of heart failure and certain cardiac arrhythmias due to their positive inotropic (contractility-enhancing) and negative chronotropic (heart rate-slowing) effects on the heart.
* Saponin glycosides have potent detergent properties and can cause hemolysis (rupture of red blood cells). They are used in various industries, including cosmetics and food processing, and have potential applications in drug delivery systems.
* Some glycosides, like amygdalin found in apricot kernels and bitter almonds, can release cyanide upon hydrolysis, making them potentially toxic.

It is important to note that while some glycosides have therapeutic uses, others can be harmful or even lethal if ingested or otherwise introduced into the body in large quantities.

Antiprotozoal agents are a type of medication used to treat protozoal infections, which are infections caused by microscopic single-celled organisms called protozoa. These agents work by either killing the protozoa or inhibiting their growth and reproduction. They can be administered through various routes, including oral, topical, and intravenous, depending on the type of infection and the severity of the illness.

Examples of antiprotozoal agents include:

* Metronidazole, tinidazole, and nitazoxanide for treating infections caused by Giardia lamblia and Entamoeba histolytica.
* Atovaquone, clindamycin, and pyrimethamine-sulfadoxine for treating malaria caused by Plasmodium falciparum or other Plasmodium species.
* Pentamidine and suramin for treating African trypanosomiasis (sleeping sickness) caused by Trypanosoma brucei gambiense or T. b. rhodesiense.
* Nitroimidazoles, such as benznidazole and nifurtimox, for treating Chagas disease caused by Trypanosoma cruzi.
* Sodium stibogluconate and paromomycin for treating leishmaniasis caused by Leishmania species.

Antiprotozoal agents can have side effects, ranging from mild to severe, depending on the drug and the individual patient's response. It is essential to follow the prescribing physician's instructions carefully when taking these medications and report any adverse reactions promptly.

Spectrophotometry, Ultraviolet (UV-Vis) is a type of spectrophotometry that measures how much ultraviolet (UV) and visible light is absorbed or transmitted by a sample. It uses a device called a spectrophotometer to measure the intensity of light at different wavelengths as it passes through a sample. The resulting data can be used to determine the concentration of specific components within the sample, identify unknown substances, or evaluate the physical and chemical properties of materials.

UV-Vis spectroscopy is widely used in various fields such as chemistry, biology, pharmaceuticals, and environmental science. It can detect a wide range of substances including organic compounds, metal ions, proteins, nucleic acids, and dyes. The technique is non-destructive, meaning that the sample remains unchanged after the measurement.

In UV-Vis spectroscopy, the sample is placed in a cuvette or other container, and light from a source is directed through it. The light then passes through a monochromator, which separates it into its component wavelengths. The monochromatic light is then directed through the sample, and the intensity of the transmitted or absorbed light is measured by a detector.

The resulting absorption spectrum can provide information about the concentration and identity of the components in the sample. For example, if a compound has a known absorption maximum at a specific wavelength, its concentration can be determined by measuring the absorbance at that wavelength and comparing it to a standard curve.

Overall, UV-Vis spectrophotometry is a versatile and powerful analytical technique for quantitative and qualitative analysis of various samples in different fields.

A plant root is not a medical term per se, but it is a term from botany, which is the study of plants. However, I can certainly provide a definition for you.

Plant roots are the underground organs of a plant that typically grow downward into the soil. They serve several important functions, including:

1. Anchorage: Roots help to stabilize the plant and keep it upright in the ground.
2. Absorption: Roots absorb water and nutrients from the soil, which are essential for the plant's growth and development.
3. Conduction: Roots conduct water and nutrients up to the above-ground parts of the plant, such as the stem and leaves.
4. Vegetative reproduction: Some plants can reproduce vegetatively through their roots, producing new plants from root fragments or specialized structures called rhizomes or tubers.

Roots are composed of several different tissues, including the epidermis, cortex, endodermis, and vascular tissue. The epidermis is the outermost layer of the root, which secretes a waxy substance called suberin that helps to prevent water loss. The cortex is the middle layer of the root, which contains cells that store carbohydrates and other nutrients. The endodermis is a thin layer of cells that surrounds the vascular tissue and regulates the movement of water and solutes into and out of the root. The vascular tissue consists of xylem and phloem, which transport water and nutrients throughout the plant.

Alkyl and aryl transferases are a group of enzymes that catalyze the transfer of alkyl or aryl groups from one molecule to another. These enzymes play a role in various biological processes, including the metabolism of drugs and other xenobiotics, as well as the biosynthesis of certain natural compounds.

Alkyl transferases typically catalyze the transfer of methyl or ethyl groups, while aryl transferases transfer larger aromatic rings. These enzymes often use cofactors such as S-adenosylmethionine (SAM) or acetyl-CoA to donate the alkyl or aryl group to a recipient molecule.

Examples of alkyl and aryl transferases include:

1. Methyltransferases: enzymes that transfer methyl groups from SAM to various acceptor molecules, such as DNA, RNA, proteins, and small molecules.
2. Histone methyltransferases: enzymes that methylate specific residues on histone proteins, which can affect chromatin structure and gene expression.
3. N-acyltransferases: enzymes that transfer acetyl or other acyl groups to amino groups in proteins or small molecules.
4. O-acyltransferases: enzymes that transfer acyl groups to hydroxyl groups in lipids, steroids, and other molecules.
5. Arylsulfatases: enzymes that remove sulfate groups from aromatic rings, releasing an alcohol and sulfate.
6. Glutathione S-transferases (GSTs): enzymes that transfer the tripeptide glutathione to electrophilic centers in xenobiotics and endogenous compounds, facilitating their detoxification and excretion.

... the diterpene synthases and cytochromes P450. Several diterpenes are produced by plants and cyanobacteria. GGPP is also the ... Diterpenes are a class of terpenes composed of four isoprene units, often with the molecular formula C20H32. They are ... Diterpenes form the basis for biologically important compounds such as retinol, retinal, and phytol. They are known to be ... Diterpenes are derived from the addition of one IPP unit to FPP to form geranylgeranyl pyrophosphate (GGPP). From GGPP, ...
... Chem Pharm Bull (Tokyo). 1978 Oct;26(10):3117- ...
"Diterpenes, Abietane" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical ... This graph shows the total number of publications written about "Diterpenes, Abietane" by people in Harvard Catalyst Profiles ... Below are the most recent publications written about "Diterpenes, Abietane" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Diterpenes, Abietane". ...
Diterpene Discovered Using Isotope Labeling. Author: ChemistryViews.org. Herpetosiphon aurantiacus 114-95T is a predatory ... Herpetopanone, a diterpene from Herpetosiphon aurantiacus discovered by isotope labeling,. Xinli Pan, Nicole Domin, Sebastian ... a diterpene with the formula C20H36O4. ...
Because processes of excretion and accumulation of this labdane diterpene are unknown, the aim of this work was to gain ... To our knowledge, this study is the first report of a diterpene forming epicuticular crystals. Nevertheless, other diterpenes ... Extracellular Localization of the Diterpene Sclareol in Clary Sage (Salvia sclarea L., Lamiaceae). *Jean-Claude Caissard, ... A similar mechanism of secretion has been assumed to take place for other diterpenes in tobacco such as cis-abienol [60], ...
The neoclerodane diterpene salvinorin A, isolated from Salvia divinorum, is an example of a furan-containing natural product. ... Palladium-catalyzed Transformations of Salvinorin A, a Neoclerodane Diterpene from Salvia divinorum. ... a Neoclerodane Diterpene from Salvia divinorum. Organic Letters, 15(23), 5936-5939. http://doi.org/10.1021/ol4027528 ...
Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews. / Urgert, R.; van der Weg, G.; ... Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews. In: Journal of Agricultural and ... Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews. Journal of Agricultural and Food ... title = "Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee brews", ...
Stavri, Michael, Paton, Alan, Skelton, Brian W. and Gibbons, Simon (2009) Antibacterial diterpenes from Plectranthus ernstii. ... All three diterpenes exhibited antimycobacterial activity against three strains of rapidly growing mycobacteria with MIC values ...
Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. R. Driller ... Here, we present the structure of the diterpene synthase CotB2, in complex with an in crystallo cyclised abrupt reaction ... Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis ... Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis ...
Bascombe K, Gibbons S. Anti-staphylococcal activity of novel diterpenes isolated from Pycnostachys reticulata. 2008. Abstract ... Bascombe, K. ; Gibbons, S. / Anti-staphylococcal activity of novel diterpenes isolated from Pycnostachys reticulata. Abstract ... Bascombe, K., & Gibbons, S. (2008). Anti-staphylococcal activity of novel diterpenes isolated from Pycnostachys reticulata. ... Bascombe, K & Gibbons, S 2008, Anti-staphylococcal activity of novel diterpenes isolated from Pycnostachys reticulata, 7th ...
Fries, N. "Specific effects of diterpene resin acids on spore germination of ectomycorrhizal basidiomycetes." Experientia 44.11 ... Fries, N. "Specific effects of diterpene resin acids on spore germination of ectomycorrhizal basidiomycetes." Experientia 44.11 ... Fries, N. "Specific effects of diterpene resin acids on spore germination of ectomycorrhizal basidiomycetes." Experientia 44.11 ...
Boger, D. L., & Searcey, M. (1998). The first synthesis of a daphnane diterpene: The enantiocontrolled total synthesis of (+)- ... Boger, DL & Searcey, M 1998, The first synthesis of a daphnane diterpene: The enantiocontrolled total synthesis of (+)- ... The first synthesis of a daphnane diterpene : The enantiocontrolled total synthesis of (+)-resiniferatoxin. / Boger, Dale L.; ... The first synthesis of a daphnane diterpene: The enantiocontrolled total synthesis of (+)-resiniferatoxin. Chemtracts. 1998 Aug ...
Smith, E. C. J., Gibbons, S., Wareham, N., & Zloh, M. (2008). 2β-Acetoxyferruginol - A new antibacterial abietane diterpene ... Smith, ECJ, Gibbons, S, Wareham, N & Zloh, M 2008, 2β-Acetoxyferruginol - A new antibacterial abietane diterpene from the bark ... N2 - As part of an on-going project to isolate antibacterial compounds from rare conifer species, a new abietane diterpene, 2β- ... AB - As part of an on-going project to isolate antibacterial compounds from rare conifer species, a new abietane diterpene, 2β- ...
Stereospecific syntheses of intermediates to the diterpene alkaloids and the C20 gibberellins Journal of the American Chemical ... Stereospecific syntheses of intermediates to the diterpene alkaloids and the C20 gibberellins ...
Structural and conformational studies on euphornin and related diterpenes」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。 ... Structural and conformational studies on euphornin and related diterpenes. In: Tetrahedron Letters. 1984 ; Vol. 25, No. 11. pp ... Structural and conformational studies on euphornin and related diterpenes. Tetrahedron Letters. 1984;25(11):1155-1158. doi: ... Structural and conformational studies on euphornin
Isoreiswigin, a new diterpene from a marine sponge. / Kashman, Y.; Hirsch, S. In: Journal of Natural Products, Vol. 54, No. 5, ... Kashman, Y., & Hirsch, S. (1991). Isoreiswigin, a new diterpene from a marine sponge. Journal of Natural Products, 54(5), 1430- ... Kashman Y, Hirsch S. Isoreiswigin, a new diterpene from a marine sponge. Journal of Natural Products. 1991 Sep 1;54(5):1430- ... Kashman, Y. ; Hirsch, S. / Isoreiswigin, a new diterpene from a marine sponge. In: Journal of Natural Products. 1991 ; Vol. 54 ...
Diterpenes / pharmacology* * Dose-Response Relationship, Drug * Down-Regulation * Epoxy Compounds / pharmacology * Gene ...
Lycasin is a trade name given by Roquette for hydrogenated glucose syrup (hydrogenated starch hydrolysates).[1] One of the major components of Lycasin is maltitol, derived from the hydrogenation of maltose. Depending on the dextrose equivalent (DE) of the syrup used in the hydrolysis, a variety of products can be made, with the name "lycasin" normally being reserved for lycasin 80/55 (80 referring to the dry content and 55 to the dextrose equivalent). The other grades (e.g. 75/60 and 80/33) are referred to as Polysorb,[2] but should not be confused with the polyglycolic acid suture of the same name which is produced by a different company.[3] Lycasins known side effects in adults include bloating, intestinal gurgling or rumbling (borborygmi), and flatulence.[4] Some cases of extremely intense intestinal distress have been reported from consuming foods containing Lycasin, which led to many humorous reviews of German confectioner Haribos Sugarless Gummy Bears.[5] ...
Chemical studies of north adriatic seaweeds-I new dolabellane diterpenes from the brown alga dilophus fasciola. / De Rosa, S.; ... Chemical studies of north adriatic seaweeds-I new dolabellane diterpenes from the brown alga dilophus fasciola. In: Tetrahedron ... Dive into the research topics of Chemical studies of north adriatic seaweeds-I new dolabellane diterpenes from the brown alga ... title = "Chemical studies of north adriatic seaweeds-I new dolabellane diterpenes from the brown alga dilophus fasciola", ...
Poinsettia plants, commonly used during the holidays, are not poisonous. In most cases, eating this plant does not result in a trip to the hospital.
Daphnane (diterpene ester). Adapted from Lovell CR;[2] McGovern TW, Barkley TM;[9] Mascarenhas R et al;[25] Karaca S et al;[27] ... diterpene esters, alkaloids, and other chemical irritants such as naphthoquinone and acids. ...
N2 - A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon pseudo- ... AB - A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon pseudo- ... A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon pseudo- ... abstract = "A new ent-kaurene diterpene, pseudoirroratin A (1), and a known diterpene, pseurata A, were isolated from Isodon ...
These diterpenes were evaluated by molecular docking, and it was identified that only dolabelladienetriol interacted in the ... In the structure-activity relationship, descriptors were identified associating the anti-HIV activity of five diterpenes with ... Structure-activity relationship, molecular docking, and molecular dynamic studies of diterpenes from marine natural products ...
Peter Forgo, Dóra Rédei, Zsanett Hajdu, Pál Szabó, László Szabó, and Judit Hohmann . Unusual Tigliane Diterpenes from Euphorbia ...
Arabica beans contain the highest concentrations of cholesterol-raising diterpenes, compared with Robusta beans, they sai... ... Quote The researchers added that the type of coffee and grind may factor into the levels of diterpenes, cafestol and kahweol ... Is green Robusta coffee better than regular coffee? Does it have more diterpenes? Can it be prepared the same way as tea? ... InquilineKea changed the title to Is green Robusta coffee better than regular coffee? Does it have more diterpenes? Can it be ...
A Unified Approach to ent-Atisane Diterpenes and Related Alkaloids: Synthesis of (-)-Methyl Atisenoate, (-)-Isoatisine, and the ...
Pimarane diterpenes are a kind of tricyclic diterpene, generally isolated from plant and fungi. In nature, fungi distribute ... Pimarane diterpenes are a kind of tricyclic diterpene, generally isolated from plant and fungi. In nature, fungi distribute ... This review may be useful improving the understanding of pimarane diterpenes from fungi. Full article ... They provide many secondary metabolites, including pimarane diterpenes, with novel skeletons and bioactivities. These natural ...
The antibacterial activity of 13-epi-sclareol, a labdane type diterpene, isolated from the resinous exudate of Pseudognaphalium ... ANTIBACTERIAL ACTIVITY OF 13-EPI-SCLAREOL, A LABDANE TYPE DITERPENE ISOLATED FROM PSEUDOGNAPHALIUM HETEROTRICHIUM AND P. ... ANTIBACTERIAL ACTIVITY OF 13-EPI-SCLAREOL, A LABDANE TYPE DITERPENE ISOLATED FROM PSEUDOGNAPHALIUM HETEROTRICHIUM AND P. ...
1] Diterpenes contain 4 isoprene units; examples include phytol, vitamin A1, [2] and paclitaxel (Taxol). ...
ANTIFUNGAL CLERODANE DITERPENES FROM MACARANGA MONANDRA (L) MUELL. ET ARG. (EUPHORBIACEAE) (Peer Reviewed Journal) (3-Oct-03) ...

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