Enuresis
Antidiuretic Agents
Circadian Rhythm
A United Kingdom population-based study of intellectual capacities in children with and without soiling, daytime wetting, and bed-wetting. (1/7)
OBJECTIVE: The objective of this study was to examine differences in intellectual capacities between children with and without soiling, daytime wetting, and bed-wetting. METHODS: This study was based on a population of >6000 children (age range: 7 years 6 months to 9 years 3 months; median: 7 years 6 months) from the United Kingdom-based Avon Longitudinal Study of Parents and Children. Data on wetting and soiling were obtained from a questionnaire completed by parents. The Wechsler Intelligence Scale for Children-Third Edition was administered at a research clinic. RESULTS: Bed-wetting was associated with lower Wechsler Intelligence Scale for Children-Third Edition IQ scores compared with control subjects, particularly performance IQ. This difference remained after exclusion of children with an IQ of <70 and adjustment for gender, stressful life events, and sociodemographic background. There were fewer differences in IQ scores between children with and without soiling or daytime wetting. Co-occurring wetting and soiling were associated with lower IQ scores than isolated soiling, daytime wetting, or bed-wetting, but this was mostly attributable to an overrepresentation of children with an IQ of <70 in the co-occurrence group. CONCLUSIONS: It is hypothesized that the differences in intellectual capacities between children with and without bed-wetting are associated with maturational deficits of the central nervous system. There was less evidence for differences in intellectual capacities between children with and without soiling and daytime wetting. The central nervous system is involved to a lesser extent in soiling and daytime wetting, because peripheral influences from the bladder and gut play a greater role. (+info)Early childhood risk factors associated with daytime wetting and soiling in school-age children. (2/7)
(+info)Urinary frequency in community-dwelling women: what is normal? (3/7)
(+info)The hypoxic ventilatory response and ventilatory long-term facilitation are altered by time of day and repeated daily exposure to intermittent hypoxia. (4/7)
(+info)Daytime urinary incontinence among kindergarten children in Aden Governorate, 2003. (5/7)
Daytime urinary incontinence is an involuntary or intentional voiding of urine in an awake child who is old enough to have developed control, and has a variable prevalence throughout the world. In Yemen, data regarding this problem are almost absent. In this study from the capital city of Aden, we aimed to: (1) determine the prevalence of daytime incontinence in kindergarten children aged 4-6 years, (2) identify the relation between daytime enuresis with personal and family characteristics of the children studied, and (3) describe the severity and characteristics of daytime enuresis in the studied children. A cross-sectional comparative study was undertaken in all kindergarten children aged 4-6 years in Aden Governorate and 1061 responded. Data were obtained by using a precoded self-administered questionnaire completed by the parents. The questionnaire consisted of two parts: personal and family characteristics of the studied children and the presence of daytime incontinence. The second part was responded if there was history of daytime incontinence, and contained information on the severity and possible associated factors. Daytime incontinence was encountered in 34 cases (3.2%); 18 were females. Significant differences between cases and incontinence-free children were encountered in birth order and type of kindergarten (P < 0.05). Majority (85.3%) had severe form of daytime incontinence. Bed wetting and combined day and night wetting were more frequent among males, whereas urinary symptoms (urgency, squatting, dysuria, dribbling) were more frequent among females. Working mother and frightening and emotionally stressful events in the 6 months preceding the study were significantly associated with daytime incontinence, while parents' education, punishment for daytime incontinence, and the presence of family history of incontinence were insignificant. In conclusion, this is the first study from Yemen reporting the prevalence of enuresis, similar to previous reports. Further studies are needed to explore this problem in our region to end the misery of the child and the family. (+info)Urinary incontinence in children. (6/7)
(+info)Monosymptomatic and non-monosymptomatic nocturnal enuresis: a clinical evaluation. (7/7)
(+info)Enuresis is a medical term that refers to the involuntary or unconscious release of urine, especially at night during sleep, in children who are at least 5 years old. It's commonly known as bedwetting. Enuresis can be classified into two types: primary and secondary. Primary enuresis occurs when a child has never achieved consistent dryness during sleep, while secondary enuresis happens when a child starts wetting the bed again after having been dry for at least six months.
Enuresis can have various causes, including developmental delays, small bladder capacity, urinary tract infections, constipation, sleep disorders, and emotional stress. In some cases, it may also be associated with genetic factors. Treatment options depend on the underlying cause and may include behavioral interventions, bladder training, alarm systems, medication, or a combination of these approaches.
Diurnal enuresis is a medical term that refers to the involuntary or unconscious passage of urine during waking hours. It is also known as "daytime wetting." This condition is most commonly seen in children, but it can affect people of any age. Diurnal enuresis can be caused by a variety of factors, including constipation, urinary tract infections, and certain neurological conditions. In some cases, it may be a sign of an underlying medical issue, so it is important to speak with a healthcare provider if you or someone you know is experiencing this problem. Treatment for diurnal enuresis may include behavioral modifications, such as bladder training exercises, and/or medication.
Antidiuretic agents are medications or substances that reduce the amount of urine produced by the body. They do this by increasing the reabsorption of water in the kidneys, which leads to a decrease in the excretion of water and solutes in the urine. This can help to prevent dehydration and maintain fluid balance in the body.
The most commonly used antidiuretic agent is desmopressin, which works by mimicking the action of a natural hormone called vasopressin (also known as antidiuretic hormone or ADH). Vasopressin is produced by the pituitary gland and helps to regulate water balance in the body. When the body's fluid levels are low, vasopressin is released into the bloodstream, where it causes the kidneys to reabsorb more water and produce less urine.
Antidiuretic agents may be used to treat a variety of medical conditions, including diabetes insipidus (a rare disorder that causes excessive thirst and urination), bedwetting in children, and certain types of headaches. They may also be used to manage fluid balance in patients with kidney disease or heart failure.
It is important to use antidiuretic agents only under the supervision of a healthcare provider, as they can have side effects and may interact with other medications. Overuse or misuse of these drugs can lead to water retention, hyponatremia (low sodium levels in the blood), and other serious complications.
A circadian rhythm is a roughly 24-hour biological cycle that regulates various physiological and behavioral processes in living organisms. It is driven by the body's internal clock, which is primarily located in the suprachiasmatic nucleus (SCN) of the hypothalamus in the brain.
The circadian rhythm controls many aspects of human physiology, including sleep-wake cycles, hormone secretion, body temperature, and metabolism. It helps to synchronize these processes with the external environment, particularly the day-night cycle caused by the rotation of the Earth.
Disruptions to the circadian rhythm can have negative effects on health, leading to conditions such as insomnia, sleep disorders, depression, bipolar disorder, and even increased risk of chronic diseases like cancer, diabetes, and cardiovascular disease. Factors that can disrupt the circadian rhythm include shift work, jet lag, irregular sleep schedules, and exposure to artificial light at night.
Desmopressin, also known as 1-deamino-8-D-arginine vasopressin (dDAVP), is a synthetic analogue of the natural hormone arginine vasopressin. It is commonly used in medical practice for the treatment of diabetes insipidus, a condition characterized by excessive thirst and urination due to lack of antidiuretic hormone (ADH).
Desmopressin works by binding to V2 receptors in the kidney, which leads to increased water reabsorption and reduced urine production. It also has some effect on V1 receptors, leading to vasoconstriction and increased blood pressure. However, its primary use is for its antidiuretic effects.
In addition to its use in diabetes insipidus, desmopressin may also be used to treat bleeding disorders such as hemophilia and von Willebrand disease, as it can help to promote platelet aggregation and reduce bleeding times. It is available in various forms, including nasal sprays, injectable solutions, and oral tablets or dissolvable films.