Embryo Loss

Pregnancy

Embryo, Mammalian

Embryo, Nonmammalian

Chick Embryo

Embryo Implantation

Chick embryos5

• Clarke, P.G.H. (1984) Identical populations of phagocytes and dying neurons revealed by intravascularly injected horseradish peroxidase, and by endogenous glutaraldehyde-resistant acid phosphatase in the brains of chick embryos. (karger.com)
• Electroporation as the most popular method of the transient transfection into the chick embryos. (ox.ac.uk)
• Pretreatment of chick embryos with beta-naphthoflavone, which causes a 90-fold increase in P450 1A levels, did not increase the formation of N-vinylPP after TTMS administration, showing that the heme moiety of P450 1A does not contribute to the formation of N-vinylPP. (aspetjournals.org)
• Increased amounts of N-vinylPP were isolated from dexamethasone-, phenobarbital-, and glutethimide-pretreated chick embryos, and it is possible that P450 2H and/or a P450 3A-like isozyme contributes to the formation of N-vinylPP. (aspetjournals.org)
• The ring B-substituted (NB) regioisomer of N-vinylPP constituted the lowest percentage of the total regioisomers (9-13%) in untreated and drug-induced chick embryos, thus supporting the concept that ring B of heme is occluded by a protein residue in the P450 active site. (aspetjournals.org)

Eggs35

• An Ohio fertility clinic says more than 4,000 eggs and embryos were affected by a freezer malfunction, double the number previously thought -- and that it's unlikely any of them are viable. (news5cleveland.com)
• The University Hospitals Fertility Clinic in Cleveland is facing dozens of legal actions after the failure in early March of a cryopreservation tank containing approximately 4,000 eggs and embryos belonging to at least 950 families. (news5cleveland.com)
• Many families held out hope that their eggs or embryos might have been saved. (news5cleveland.com)
• University Hospitals delivered the news that all contents of the tank had been lost -- more than 4,000 eggs and embryos -- in a letter to the 950 families dated March 26. (news5cleveland.com)
• But now scientists have successfully four eggs from Najin and six from Fatu and fertilised them with sperm from a dead male, creating three viable embryos which they are hoping to implant into a surrogate later this year. (telegraph.co.uk)
• We learned that we had the option to freeze eggs or freeze embryos. (tevapharm.com)
• However, with embryo freezing, my husband's sperm would fertilize the eggs before they were frozen. (tevapharm.com)
• As we learned, frozen embryos may survive better than frozen eggs. (tevapharm.com)
• If you choose to preserve eggs rather than embryos, the fertility team freezes the eggs they retrieve. (tevapharm.com)
• If you choose embryo preservation, healthy-looking eggs are fertilized with sperm. (tevapharm.com)
• A March 9th Washington Post article noted an unfortunate malfunction that resulted in the loss of thousands of frozen eggs and embryos, some of which had been in storage for decades. (healthcarepackaging.com)
• A liquid nitrogen storage tank at University Hospitals Ahuja Medical Center in Beechwood, OH rose in temperature possibly affecting more than 2,000 frozen eggs and embryos. (healthcarepackaging.com)
• This video guide is an essential learning tool for investigators considering work with Xenopus eggs and embryos. (cshlpress.com)
• Eggs need to lose the correct amount of water (weight) so the embryos can build the internal air cell needed for pulmonary respiration. (petersime.com)
• Researchers have found that transferring frozen then thawed embryos to women's wombs from eggs collected in the summer resulted in a 30% higher likelihood of babies born alive, than if the eggs had been retrieved in the autumn. (sciencedaily.com)
• Pacific Fertility Center recently emailed clients of an "unfortunate incident," resulting in damaged embryos, eggs and biologic tissue. (walkuplawoffice.com)
• If you use this fertility clinic's services and received this email, you may be able to sue over the cryo-storage tank failure and loss of frozen eggs. (walkuplawoffice.com)
• But human eggs and embryos are not fungible. (walkuplawoffice.com)
• He did not tell purchasers of PFC storage services the full extent of the damage to embryos, unfertilized eggs, sperm, tissue and other material. (walkuplawoffice.com)
• Her expertise encompasses diagnosing and treating irregular periods, polycystic ovarian syndrome, recurrent pregnancy loss, primary ovarian insufficiency (when the ovaries prematurely stop producing eggs) and endometriosis. (ucsfhealth.org)
• All treatments or procedures that include the handling of human eggs or embryos to help a woman become pregnant. (cdc.gov)
• Retrieved eggs are combined with sperm to create embryos. (cdc.gov)
• An ART cycle in which ovarian stimulation was performed but the cycle was stopped before eggs were retrieved or before embryos were transferred. (cdc.gov)
• The practice of freezing eggs or embryos from a patient's ART cycle for potential future use. (cdc.gov)
• An ART cycle started with the intent of freezing (cryopreserving) all resulting eggs or embryos for potential future use. (cdc.gov)
• An ART cycle started with the intent of freezing and banking all eggs or embryos for at least 12 months for future use. (cdc.gov)
• Fresh eggs, sperm, or embryos. (cdc.gov)
• Eggs, sperm, or embryos that have not been frozen. (cdc.gov)
• The fresh embryos are conceived with fresh or frozen eggs and fresh or frozen sperm. (cdc.gov)
• Five patients of a California fertility center have been awarded a total of $15m after a freezing tank failed, rendering some of more than 3,500 frozen human embryos and eggs unviable. (yahoo.com)
• It marks the first time a jury has awarded damages in a case involving the destruction of eggs and embryos. (yahoo.com)
• At the trial, the freezer manufacturer argued that the error was caused by fertility clinic lab employees unplugging the tank's malfunctioning controller and then keeping eggs and embryos in a container with no temperature-alert system in operation for 17 days. (yahoo.com)
• Nothing can bring these eggs and embryos back," Sharp said. (yahoo.com)
• Wolf, meanwhile, said many of those who had lost eggs and embryos, were still struggling with their loss. (yahoo.com)
• More than 4,000 eggs and embryos were lost at the University Hospitals Fertility Clinic in Cleveland. (yahoo.com)

Implantation12

• Our virtual reconstructions show the developing embryo and its supporting tissues in the days after implantation in incredible detail," said Boroviak. (genengnews.com)
• The pre-implantation period, before the developing embryo implants into the mother's womb, has been studied extensively in human embryos in the lab. (genengnews.com)
• Embryo-like models with spatially organized morphogenesis and structure of all defining embryonic and extra-embryonic tissues of the post-implantation human conceptus (that is, the embryonic disc, the bilaminar disc, the yolk sac, the chorionic sac and the surrounding trophoblast layer) remain lacking 1 , 2 . (nature.com)
• Such human fully integrated and complete SEMs recapitulate the organization of nearly all known lineages and compartments of post-implantation human embryos, including the epiblast, the hypoblast, the extra-embryonic mesoderm and the trophoblast layer surrounding the latter compartments. (nature.com)
• Implantation of the human embryo leads to a number of changes in organization that are essential for gastrulation and future development 1 . (nature.com)
• and (3) evidence of developmental dynamism relating to ability to progress, in a structurally organized manner, through morphologically characterized developmental milestones of the early post-implantation human embryo following initial aggregate formation 3 . (nature.com)
• Najib Balala, Kenya's Cabinet Secretary for Tourism, said: "The Kenyan government is delighted that the Northern White Rhino IVF project, has been able to successfully produce three pure Northern White Rhinos embryos ready for implantation into the Southern White Rhino as surrogate in the coming months. (telegraph.co.uk)
• The advantage of a day 5 or blastocyst transfer is a higher implantation and pregnancy rate per embryo transferred since less "strong" embryos will not survive, and therefore the scientists and physicians are stressing all of the embryos to detect the best quality embryos and also decrease the chance of multiples such as twins, by transferring fewer embryos. (sbivf.com)
• In rats, implantation loss, decreased environment. (cdc.gov)
• There were also no significant differences between the groups in rates of implantation, clinical pregnancy, overall pregnancy loss, and ongoing pregnancy. (yale.edu)
• This makes it impossible to separate the potential impacts of environmental factors, such as season and hours of sunshine, on egg development and on embryo implantation and early pregnancy development. (sciencedaily.com)
• A zygotic-specific promoter of Dnmt3l is activated following gametic methylation loss and the potential recruitment of pluripotency factors just before implantation. (bvsalud.org)

Zebrafish embryos3

• Hours of footage of zebrafish embryos let researchers capture and study this key moment in development. (nature.com)
• An impressive combination of computational modelling and experimental techniques in live zebrafish embryos reveals how the heart initiates its organized and rhythmic beating. (nature.com)
• We characterize the activation kinetics of these reagents in vitro and demonstrate their efficacy in zebrafish embryos that express NfsB either ubiquitously or in defined cell populations. (cdc.gov)

Fresh-embryo transfers2

• The study, however, did find that frozen-embryo transfers resulted in a significantly lower risk of ovarian hyperstimulation syndrome (OHSS) than women using fresh-embryo transfers. (yale.edu)
• Most studies looking at IVF success rates have looked at fresh embryo transfers, where the embryo is put back within a week of the egg being collected. (sciencedaily.com)

Vitro9

• To address the high rate of multiple births resulting from in-vitro-fertilization (IVF), researchers at Yale School of Medicine and McGill University have developed a procedure that estimates the reproductive potential of individual embryos, possibly leading to a decrease in multiple-infant births and a higher success rate in women undergoing IVF. (health.am)
• The main reason for multiple gestations following in-vitro fertilization is the inability to precisely estimate the reproductive potential of individual embryos," Seli said. (health.am)
• The successes of in-vitro fertilization often result from simultaneous transfer of multiple embryos with the hope that at least one will lead to a pregnancy. (health.am)
• Supernumerary in vitro fertilized human embryos were warmed at day 3, and cultured for 2, 9, or 24 hr to examine the localization of polarization markers. (elifesciences.org)
• What is the chance that a day 3 embryo that would have arrested on day 5 in vitro would have a better shot in utero? (sbivf.com)
• However, other procedures based on the in vivo and in vitro production of equine embryos have emerged in recent years. (ivis.org)
• Reasons for the delayed development of in vivo and in vitro production of equine embryos include the scarce availability of abattoir ovaries and the lack of interest from horse breeders and registries. (ivis.org)
• Many women struggling to have a baby turn to in-vitro fertilization to improve their chances, and then face further uncertainty and anxiety when confronted with the decision of whether to use frozen or fresh embryos. (yale.edu)
• In this study, published in the New England Journal of Medicine, Heping Zhang of the Yale School of Public Health (YSPH) collaborated with scientists from throughout China and monitored 2,157 women who were undergoing their first in-vitro fertilization cycle and were randomly assigned either fresh or frozen embryos. (yale.edu)

Pregnancy loss8

• This will guide work to understand birth defects and pregnancy loss in humans. (genengnews.com)
• Failure of development during this time is one of the major causes of early pregnancy loss and birth defects. (genengnews.com)
• Early pregnancy loss is defined as the termination of pregnancy before 20 weeks' gestation or with a fetal weight of below 500 g. (medscape.com)
• According to the definition set forth by the American Society for Reproductive Medicine, recurrent pregnancy loss is a disease distinct from infertility and is defined by the spontaneous loss of two or more pregnancies. (medscape.com)
• However, couples in whom pregnancy loss can be attributed to a balanced translocation may benefit from specific genetic testing by preimplantation genetic diagnosis (PGD). (medscape.com)
• Anatomic uterine defects can cause obstetric complications, including recurrent pregnancy loss, preterm labor and delivery, and malpresentation. (medscape.com)
• Clinicians should encourage life-style changes and counseling for preventable exposures to reduce the risk of environmentally related pregnancy loss. (medscape.com)
• Miscarriage A miscarriage is a pregnancy loss before 20 weeks of pregnancy. (msdmanuals.com)

Sperm3

• The project to revive the Northern White population has been ongoing for several years but it was not until 2018 that scientists successfully achieved the first test-tube rhino embryo from the frozen sperm of a Northern White male and the egg from a Southern White female. (telegraph.co.uk)
• The penetration of the egg by the sperm and the resulting combining of genetic material that develops into an embryo. (cdc.gov)
• When a normal sperm cell fertilizes one of these oocytes, the resulting embryo has only one set of chromosomes. (medlineplus.gov)

20022

• In 2002, 3.1 embryos on average were transferred in IVF cycles, but only 34.3 percent resulted in pregnancies. (health.am)
• 2002). Loss-of-function experiments are also possible using electroporation of dominant-negative constructs that act as competitive inhibitors (Bel-Vialar et al. (ox.ac.uk)

Fetal4

• Loss during the stages of prenatal development after organogenesis of the fetus generally results in the similar process of fetal resorption or miscarriage. (wikipedia.org)
• It also has implications for problems such as fetal loss, tumor development, birth defects and mental retardation. (sciencedaily.com)
• Embryo-Fetal Toxicity: Abiraterone acetate can cause fetal harm. (nih.gov)
• Embryo-fetal toxicity. (renalandurologynews.com)

Tissue6

• Failed development of an embryo often results in the disintegration and assimilation of its tissue in the uterus, known as embryo resorption. (wikipedia.org)
• The (very small) embryo is usually passed within this blood and tissue in such a way that it goes unnoticed by the woman. (womenonwaves.org)
• Frequently, the embryo expelled during a medical abortion is not explicitly visible because it is passed together with other pregnancy tissue and blood 17 . (womenonwaves.org)
• When that happens, too many X chromosome genes are active, there are problems forming placental tissue, and female embryos die. (sciencedaily.com)
• Electroporation of chicken embryos involves application of an electric field to the exposed tissue that transiently disrupts the stability of the cell plasma membrane, creating reversible pores through which nucleic acids or their analogues can be readily transported into the cytosol. (ox.ac.uk)
• As a result, embryos, tissue and other genetic material experienced a rise in temperature beyond that which is required by good and accepted practice, as well as facility standards. (walkuplawoffice.com)

Implant3

• The team is hoping to implant the embryos into young, fertile Southern White Rhinos as it is too risky to carry out the procedure on the last remaining Northerns. (telegraph.co.uk)
• We were beginning to think none of the embryos would implant. (nightlight.org)
• Unfortunately the only way to determine if an egg or embryo is still viable is to thaw and implant it. (healthcarepackaging.com)

Blastocyst1

• Transferring 1 day 5 embryo (blastocyst) has almost the same pregnancy rate as transferring 2 day 3 embryos, and almost no chance of twins (compared to a 20% chance of twins transferring 2 day 3 embryos). (sbivf.com)

Fetus2

• Understanding given to choosing the therapy that will best safeguard the physiology of pregnancy, the factors that influence the maternal health and the well-being of the embryo or fetus. (cdc.gov)
• Normally, the embryo would develop into a fetus and the placenta would grow to provide nutrients to the growing fetus. (medlineplus.gov)

Placenta4

• Can you see the products of the abortion (placenta, embryo, blood) and what should you do with them? (womenonwaves.org)
• The early placenta, acting as an intermediary between embryo and mother, is in yellow. (genengnews.com)
• The team discovered that asymmetric signals come from the embryo itself and from transient structures that support the embryo during its development-the amnion, yolk sac, and precursors of the placenta. (genengnews.com)
• A hydatidiform mole is a mass that forms early in pregnancy and is made up of cells from an abnormally developed embryo and placenta. (medlineplus.gov)

Developmental3

• e ) Representative images of human embryos fixed at different developmental time-points (as shown in a) and immunostained for F-actin and PARD6. (elifesciences.org)
• The chicken embryo has been used as a classical embryological model for studying developmental events because of its ready availability, similarity to the human embryos, and amenability to embryological and surgical manipulations. (ox.ac.uk)
• By combining developmental and genetic approaches, we find that mouse embryos begin development with a maternal store of Dnmt3L, which is rapidly degraded and does not participate in embryonic de novo methylation . (bvsalud.org)

Survive5

• Embryo loss often happens without an awareness of pregnancy, and an estimated 40 to 60% of all embryos do not survive. (wikipedia.org)
• On the seventh day, the embryo implants into the womb to survive and develop. (genengnews.com)
• In the new research, female embryos without a functioning eed do not survive because of problems in forming placentas. (sciencedaily.com)
• Not all embryos can survive in a laboratory this long, although they can result in normal pregnancies if transferred on day 3 of laboratory development. (sbivf.com)
• This method does not improve the chance of pregnancy from any individual embryo, it only finds the strongest that survive. (sbivf.com)

Fertilization4

• Embryo loss (also known as embryo death) is the death of an embryo at any stage of its development which in humans, is between the second through eighth week after fertilization. (wikipedia.org)
• c ) Time at which compaction is initiated in embryos with known fertilization time. (elifesciences.org)
• We are one of the few practices that watches embryos from the moment of fertilization and evaluate progress to see if a Day 3 transfer is indicated. (sbivf.com)
• If fertilization is successful, at least one embryo is selected for transfer. (cdc.gov)

Incubator1

• Following fertilisation the embryos were monitored in a special incubator dubbed 'Geri' supplied by pharmaceutical company Merck, who shared the first images of the cell growth. (telegraph.co.uk)

Axial2

• We analyzed the morphological features of dying cells in the developing axial structures of 5 human embryos between 5 and 8 weeks of postovulatory age. (karger.com)
• According to our findings, apoptosis seems to be the most frequently observed type of PCD, but it is not the exclusive type of morphological cell death during the development of axial structures in human embryos. (karger.com)

Adoption10

• We had agreed to place any remaining embryos for adoption. (embryoadoption.org)
• If you are thinking of receiving embryos through an embryo adoption program, you may be required to complete an adoption home study. (embryoadoption.org)
• Families who longed for the laughter of a child in their home found their answer in embryo adoption. (embryoadoption.org)
• When we learned about embryo adoption, we both were immediately intrigued. (nightlight.org)
• We underwent educational training on embryo adoption and were eventually told we would be matched with an adopting couple who had donated their embryos. (nightlight.org)
• It also caused Dan and me to reconsider pursuing infant adoption instead of embryo adoption. (nightlight.org)
• But we still felt drawn to embryo adoption. (nightlight.org)
• I'm sure you can imagine the discussions and tears that went into choosing to put the embryos up for adoption. (nightlight.org)
• Many women this year are celebrating their first Mother's Day through the miracle of embryo adoption. (embryoadoption.org)
• To learn more about embryo adoption and donation, visit EmbryoAdoption.org . (embryoadoption.org)

Cycles2

• During this time there were 3659 frozen embryo transfers with embryos generated from 2155 IVF cycles in 1835 patients. (sciencedaily.com)
• ART cycles include any process in which (1) an ART procedure is performed, (2) a woman has undergone ovarian stimulation or monitoring with the intent of having an ART procedure, or (3) frozen embryos have been thawed with the intent of transferring them to a woman. (cdc.gov)

Transfers4

• At IRMS, we do both day 3 and day 5 embryo transfers. (sbivf.com)
• Certainly prior to our ability to grow embryos out in the Lab beyond Day 3 all embryo transfers were on Day 3 and tens of thousands of IVF babies were born. (sbivf.com)
• Dr Leathersich and his colleagues analysed outcomes from all frozen embryo transfers carried out at a single clinic in Perth over a period of eight years, from January 2013 to December 2021. (sciencedaily.com)
• Information on outcomes was missing for two frozen embryo transfers and so these were excluded, leaving 3657 for analysis. (sciencedaily.com)

Scientists4

• Now, scientists have illuminated early gastrulation of marmoset embryos in utero using spatial transcriptomics and stem cell-based embryo models. (genengnews.com)
• A gene discovered by scientists at the University of North Carolina at Chapel Hill appears to be crucial for female embryo survival. (sciencedaily.com)
• Scientists should carefully consider whether embryo models based on human stem cells are essential to their work because of the associated practical and ethical challenges. (nature.com)
• British Scientists from the Francis Crick Institute have sought permission from the government's fertility regulator, to genetically modify human embryos. (clarkewillmott.com)

Development13

• Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
• This work will provide a definitive laboratory reference for future studies of early embryo development, and the embryonic origins of disease," said Thorsten Boroviak, PhD, principal investigator in the laboratory for primate embryogenesis in the Centre for Trophoblast Research at the University of Cambridge. (genengnews.com)
• The second week of gestation is one of the most mysterious, yet critical, stages of embryo development. (genengnews.com)
• But with existing methods, they could not explore week two of development, after the embryo implants into the womb. (genengnews.com)
• Very little was previously known about the development of the human embryo once it implants because it becomes inaccessible for study. (genengnews.com)
• Boroviak's team used implanted embryos of the marmoset, a small New World monkey, in their study because they are very similar to human embryos at this early stage of development. (genengnews.com)
• It gets turned on early in the development of the female embryo. (sciencedaily.com)
• A light and electron microscopic study of naturally occurring and induced cell loss during development. (karger.com)
• We identified a mouse mutant that causes embryonic gonadal sex reversal: the development of ovaries in an XY embryo. (plos.org)
• We predict that loss of MAP3K4 or other MAPK components may underlie disorders of sexual development (DSD) in humans as well. (plos.org)
• This method of embryo selection is most helpful in women with so many embryos to choose from that the embryologists can't estimate which are the strongest on day 3 after retrieval, so they observe their development for a few more days. (sbivf.com)
• Embryo-Response Incubation™ technology listens to the embryo, constantly monitoring its development. (petersime.com)
• We realised this gave us an opportunity to explore the impact of environment on egg development and on early pregnancy separately by analysing the conditions at the time of egg collection independently from the conditions at the time of embryo transfer. (sciencedaily.com)

Transfer11

• So, we decided to transfer the other two embryos. (nightlight.org)
• If a patient only has 2 or 3 embryos, prolonged culture does not improve their quality, and the best chance for pregnancy is therefore an earlier transfer on day 3. (sbivf.com)
• Some patients are better served having a day 3 embryo transfer. (sbivf.com)
• I recommend all couples have the discussion with their Doctor about the transfer philosophy at their program, long before the sad phone call on day 5 that their transfer is cancelled due to the "arrest" of all of their embryos. (sbivf.com)
• Embryos produced outside the breeding season can be frozen for later transfer, which makes these techniques very versatile. (ivis.org)
• Reports by the Society for Assisted Reproductive Technology have noted that more fertility centers choose to defer embryo transfer by freezing embryos, Zhang said. (yale.edu)
• Zhang said that the findings will immediately impact patients and clinicians in their evaluation and consideration with regard to the risk and benefit of different embryo transfer strategies. (yale.edu)
• Dr Sebastian Leathersich, an obstetrician, gynaecologist and Fellow in Reproductive Endocrinology and Infertility at Fertility Specialists of Western Australia, City Fertility Centre, and the King Edward Memorial Hospital in Perth, Australia, who led the study, said: "Over the duration of our study, the average live birth rate following frozen embryo transfer in Australia was 27 births per 100 people. (sciencedaily.com)
• In our study, the overall live birth rate following frozen embryo transfer was 28 births per 100 people. (sciencedaily.com)
• When we took into account the season and conditions on the day of the embryo transfer, this improvement was still seen. (sciencedaily.com)
• Embryo transfer. (cdc.gov)

Pregnancies2

• By comparing the content of the successful and unsuccessful embryos, the team established a metabolic profile of embryos that resulted in pregnancies as well as ones that did not. (health.am)
• Until now, there have been conflicting findings on the effects of the seasons on pregnancies and live birth rates following egg collection and embryo freezing. (sciencedaily.com)

Researchers3

• A study authored by UNC researchers and published in the August issue of "Nature Genetics" furthers the understanding of a fundamental biological process in mammals and contributes important new knowledge to gene regulation in the developing embryo. (sciencedaily.com)
• Researchers say the creation of three pure Northern embryos is a 'hugely encouraging milestone' for the species showing that the procedure is safe and reproducible, and can be performed on a regular basis before the animals become too old. (telegraph.co.uk)
• Researchers found that women using frozen embryos had a live birth rate of 48.7%, versus a live birth rate of 50.2% for women in the fresh-embryo group. (yale.edu)

Birth defects1

• In the future, the team plans to use their new technique to investigate the origins of pregnancy complications and birth defects using engineered embryo models. (genengnews.com)

Gene5

• The report notes that the gene, eed, when functioning normally in female mouse embryos, keeps the paternal X chromosome inactive and many of its genes shut down in early placental cells. (sciencedaily.com)
• This gene is also involved in telling cells where to go in the embryo - to make head versus tail versus gut. (sciencedaily.com)
• Advances in technology have made it possible to screen embryos for many conditions that involve a single gene or chromosomal abnormalities, such as Down syndrome. (earth.com)
• While attempts to establish germ line transgenesis are ongoing, methods for rapid, transient spatiotemporally targeted gene alterations have thus again re-established the chick embryo as an important experimental niche by making it possible to apply genetics in concert with classical embryological techniques. (ox.ac.uk)
• NLRP7 or KHDC3L gene mutations can also prevent proper imprinting of multiple genes that contribute to a developing embryo, leading to abnormal gene activity (expression). (medlineplus.gov)

Vivo2

• Although it is possible to culture structures derived from human blastocysts ex vivo, these cultures do not recapitulate the events and structural organization of the in vivo embryos 6 ( Supplementary Information ). (nature.com)
• This study proves that the postimplantation embryo is more plastic than the germline in terms of DNA methylation mechanistic choices and, importantly, that de novo methylation can be achieved in vivo without Dnmt3L. (bvsalud.org)

Reproductive1

• We found that proton NMR, a non-invasive nuclear magnetic resonance form of spectroscopy, will determine the metabolic profile of the embryo and accurately predict its reproductive potential," said Seli, who plans to confirm the findings in a larger trial. (health.am)

Uterus1

• Placement of embryos into a woman's uterus through the cervix after IVF. (cdc.gov)

Early4

• Magnuson pointed out that X inactivation also occurs within the embryo itself, not just in early placental (trophoblast) material surrounding the embryo. (sciencedaily.com)
• Tests for antiphospholipid antibodies (APLAs), signaling the presence of the autoimmune disease antiphospholipid antibody syndrome (APS), have reportedly been positive in 10-20% of women with early pregnancy losses. (medscape.com)
• Here, we present whole-genome chromatin immunoprecipitation followed by high-throughput DNA sequencing (ChIP-seq) analyses of a wide variety of histone markers in the brain, heart, and liver of early human embryos shortly after their formation. (researchgate.net)
• The function of Dnmt3L in the early embryo remains unresolved. (bvsalud.org)

Profiling1

• Abstract #499: "Non-Invasive Metabolomic Profiling of Human Embryo Culture Media Using Proton NMR Correlates with Pregnancy Outcome. (health.am)

Fertility preservation1

• She also provides fertility preservation through egg and embryo freezing. (ucsfhealth.org)

Miscarriage1

• However, critics claim that this view is morally inconsistent due to the frequency of embryo loss/miscarriage/spontaneous abortion in general population. (wikipedia.org)

Liquid nitrogen2

• All three embryos are now stored in liquid nitrogen while conservationists hunt for a suitable female to carry the precious calves. (telegraph.co.uk)
• The loss of liquid nitrogen in the equipment caused unknown damage and harm to PFC clients. (walkuplawoffice.com)

Embryonic1

• Mouse naive embryonic stem cells have recently been shown to give rise to embryonic and extra-embryonic stem cells capable of self-assembling into post-gastrulation structured stem-cell-based embryo models with spatially organized morphogenesis (called SEMs) 3 . (nature.com)

Naturally1

• DWLS™ automatically adjusts the humidity levels to achieve this in a way that imitates the humidity levels an embryo experiences when incubated naturally by the mother hen. (petersime.com)

2,0001

• When the tank failure was found on March 4, University Hospitals said the loss was expected to be only 2,000 specimens, or nearly half of the tank's contents. (news5cleveland.com)

Viable1

• We are excited that a viable, Northern White Rhino embryo has developed with the help of Geri. (telegraph.co.uk)

Abnormal1

• Most spontaneous miscarriages are caused by an abnormal (aneuploid) karyotype of the embryo. (medscape.com)

Accurately predict1

• It cannot accurately predict IQ for each embryo, but it can single out "genetic outliers," such as embryos that are likely to have an IQ that is at least 25 points below average. (earth.com)

Underwent1

• An ART cycle in which an embryo that is donated by a patient or couple who previously underwent ART treatment and had extra embryos available is transferred to another woman (the recipient). (cdc.gov)

Genetic material1

• Our clients deserve to be compensated not for the minimal cost of another harvest cycle, but also for the lost genetic material that would have become their children and the emotional and physical toll associated with their devastating loss. (walkuplawoffice.com)

Occurs1

• As female mammals have two X chromosomes (XX) and males an X and Y (XY), imbalance occurs because female embryos have twice as many X-linked genes. (sciencedaily.com)