Ephedra sinica
Ephedra
Ephedrine
Encyclopedias as Topic
Mongolia
Cytotoxicity assessment of Ma-huang (Ephedra) under different conditions of preparation. (1/9)
Ma-huang is a traditional Chinese medicinal herb derived from EPHEDRA: sinica Stapf and other EPHEDRA: species, used to treat asthma, nose and lung congestion, and fever with anhidrosis. It contains 0.5-2.5% by weight of total alkaloids, of which ephedrine accounts for 30 to 90%. Recently, large amounts of ma-huang were used as a source of ephedrine in many dietary supplements formulated for weight reduction, because ephedrine has been found effective in inducing weight loss in diet-restricted obese patients. However, indiscriminate consumption of ma-huang-containing products has resulted in many cases of poisoning, some of which were fatal. The objective of this study is to investigate the relative toxicity of ma-huang extracted under different conditions. The toxicities of various extracts were assayed using MTT colorimetry on a battery of cell lines, while ephedrine alkaloids were analyzed with HPLC. The results are summarized as follows. (1) The cytotoxicity of all ma-huang extracts could not be totally accounted for by their ephedrine contents, suggesting the presence of other toxins in the extracts. (2) Grinding was a significant condition enhancing the toxicity of the extracts. (3) The relatively high sensitivity of the Neuro-2a cell line to the toxicity of ma-huang extracts suggests that the toxic principles were acting on neuronal cells. (4) One condition to produce a ma-huang extract with high ephedrine-to-toxins ratio would be to boil the whole herb for two h. (+info)Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. (2/9)
BACKGROUND: Dietary supplements that contain ephedra alkaloids (sometimes called ma huang) are widely promoted and used in the United States as a means of losing weight and increasing energy. In the light of recently reported adverse events related to use of these products, the Food and Drug Administration (FDA) has proposed limits on the dose and duration of use of such supplements. The FDA requested an independent review of reports of adverse events related to the use of supplements that contained ephedra alkaloids to assess causation and to estimate the level of risk the use of these supplements poses to consumers. METHODS: We reviewed 140 reports of adverse events related to the use of dietary supplements containing ephedra alkaloids that were submitted to the FDA between June 1, 1997, and March 31, 1999. A standardized rating system for assessing causation was applied to each adverse event. RESULTS: Thirty-one percent of cases were considered to be definitely or probably related to the use of supplements containing ephedra alkaloids, and 31 percent were deemed to be possibly related. Among the adverse events that were deemed definitely, probably, or possibly related to the use of supplements containing ephedra alkaloids, 47 percent involved cardiovascular symptoms and 18 percent involved the central nervous system. Hypertension was the single most frequent adverse effect (17 reports), followed by palpitations, tachycardia, or both (13); stroke (10); and seizures (7). Ten events resulted in death, and 13 events produced permanent disability, representing 26 percent of the definite, probable, and possible cases. CONCLUSIONS: The use of dietary supplements that contain ephedra alkaloids may pose a health risk to some persons. These findings indicate the need for a better understanding of individual susceptibility to the adverse effects of such dietary supplements. (+info)Determination of ephedrine alkaloids in dietary supplements and botanicals by liquid chromatography/tandem mass spectrometry: collaborative study. (3/9)
An interlaboratory study was conducted to evaluate the accuracy and precision of a method for ephedrine-type alkaloids [i.e., norephedrine (NE), norpseudoephedrine (NPE), ephedrine (E), pseudoephedrine (PE), methylephedrine (ME), and methylpseudoephedrine (MPE)] in dietary supplements and botanicals. The amount of ephedrine-type alkaloids present was determined using liquid chromatography with tandem mass selective detection. The samples were diluted to reflect a concentration of 0.0200 to 1.00 microg/mL for each alkaloid. An internal standard was added and the alkaloids were separated using a 5 microm phenyl LC column with an ammonium acetate, glacial acetic acid, acetonitrile, and water mobile phase. Eight blind duplicates of dietary supplements or botanicals were analyzed by 10 collaborators. Included was a negative control, ephedra nevadensis, and negative controls fortified at 2 different levels with each of the 6 ephedrine-type alkaloids. The spike levels were approximately 100 and 1000 microg/g for NE, 100 and 600 microg/g for NPE, 6500 and 65000 microg/g for E, 1000 and 10 000 microg/g for PE, 300 and 3000 microg/g for ME, and 100 and 1000 microg/g for MPE. On the basis of the accuracy and precision results for this interlaboratory study, it is recommended that this method be adopted Official First Action for the determination of 6 different individual ephedrine-type alkaloids in dietary supplements and botanicals. (+info)Concentrations of ephedra alkaloids and caffeine in commercial dietary supplements. (4/9)
Dietary supplements that contain Ma Huang (ephedra alkaloids) and guarana (caffeine) are widely marketed and used in the U.S. for weight loss and athletic performance enhancement, despite a lack of adequate research on the pharmacology of these botanical stimulants. We developed and applied a novel liquid chromatography-tandem mass spectrometry (LC-MS-MS) method to quantitate the various ephedra alkaloids found in dietary supplements that contain Ephedra species. The quantities of ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, methylephedine, methylpseudoephedrine, and caffeine were determined for 35 commercial dietary supplements and compared with the amounts listed on the product labels. The total ephedra alkaloid content ranged from 5.97 mg to 29.3 mg per serving. Two supplement brands did not list the quantity of ephedra alkaloids on the label, and four did not list the amount of caffeine per serving. Of the products tested, 31% contained > 110% of the total ephedra alkaloids listed on the label, and 6% of the supplements contained < 90% of the listed amount. For caffeine, 86% of the product lots that listed the caffeine amount contained less than 90% of the labeled quantity. No products contained > 110% of the declared caffeine content. The total ephedra alkaloid content varied significantly from lot to lot in 5 of 9 products. Three product brands contained proportions of alkaloids that exceeded amounts reported for E. sinica, including one that was 98% ephedrine, one that had 10% norpseudoephedrine, and one that contained an average of 13% methylephedrine. We conclude that product inconsistency is common among some commercially available dietary supplements that contain ephedra alkaloids and caffeine. (+info)Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluids. (5/9)
Dietary supplements containing botanical forms of caffeine and ephedra alkaloids have been widely promoted and used in the U.S. for weight loss and athletic enhancement despite a lack of adequate research on the pharmacology of these botanical stimulants. In order to analyze dietary supplements and perform human pharmacokinetic studies, an analytical approach with good precision and accuracy was needed with sufficient sensitivity to detect very low levels of ephedra alkaloids. A liquid chromatography-atmospheric pressure chemical ionization (APCI) tandem mass spectrometry (LC-MS-MS) method was developed for quantitating the various ephedrine-group alkaloids found in dietary supplements that contain Ephedra species, and in plasma and urine of persons consuming these supplements. Using this method, low nanogram-per-milliliter concentrations of ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, methylephedrine, methylpseudoephedrine, and caffeine can be quantitated in a 12-min LC-MS-MS run. (+info)Anti-arthritic effects of Ephedra sinica STAPF herb-acupuncture: inhibition of lipopolysaccharide-induced inflammation and adjuvant-induced polyarthritis. (6/9)
Anti-inflammatory and anti-arthritic effects of water distillates of Ephedra sinica STAPF (ES), in herb-acupuncture, on the inflammatory responses of arthritis was investigated using phorbol 12-myristate 13-acetate (PMA)/lipopolysaccharide (LPS)-induced human macrophage and adjuvant-induced arthritic rat. The luciferase reporter vectors driven by the tumor necrosis factor (TNF)-alpha and cyclooxygenase-2 promoters were transiently transfected into U937 cells, which were then differentiated and stimulated by PMA and LPS, respectively, to develop an in vitro anti-inflammation assay system. The luciferase activities, observed in the activated U937 cells, were significantly inhibited by ES herb-acupuncture, compared to those of PD98509 and berberine. To evaluate ES herb-acupuncture as a novel anti-arthritic therapy, a polyarthritic rat model was developed using heat-killed Mycobacterium tuberculosis, and 50 mul of ES distillate was subcutaneously injected into the ST36 acupoint on each knee joint. While the articular indexes of arthritic rats were evidently decreased by ES herb-acupuncture, their body weights did not regain their initial levels. This may be due to the accelerating effects of ES on weight-loss and fat consumption. The mRNA expressions of TNF-alpha and interleukin (IL)-6 genes, which were closely stimulated in the arthritic rat joints, were found to be restored to the normal levels through the ES treatment. In the case of IL-1beta, the recovery was not significant but substantial. The anti-arthritic effect of ES herb-acupuncture was not found in the ES-treated/non-acupoint group. In conclusion, the ES herb-acupuncture into the ST36 acupoint was found to be effective in alleviating the inflammatory response and thus arthritic symptoms in adjuvant-induced arthritic rats. (+info)Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system. (7/9)
Ma Huang (equivalent to 0, 12.5, 25, or 50 mg/kg ephedrine) or ephedrine (0, 6.25, 12.5, 25 mg/kg) were administered as one bolus oral dose to male F344 rats with and without caffeine. The herbal medicine Ma Huang (ephedra) in combination with caffeine caused rapid clinical signs of toxicity including salivation, hyperactivity, ataxia, and eventually lethargy, and failure to respond to stimuli. When this syndrome of clinical signs emerged, animals were moribund sacrificed, and a histological analysis for heart lesions performed. Cardiotoxicity included hemorrhage, necrosis, and degeneration in the ventricles or interventricular septum within 2-4 hours after treatment with Ma Huang (ephedra)/caffeine or ephedrine (the principal active component in Ma Huang)/caffeine. There was a steep dose response curve for cardiotoxicity with minimal toxicity seen at levels of Ma Huang (equivalent to 12.5 mg/kg ephedrine) with caffeine. However, cardiotoxic lesions occurred in 28% of animals with Ma Huang dosages equivalent to 25 mg/kg ephedrine with 15 or 30 mg/kg caffeine, and in 90% of animals at Ma Huang exposures equivalent to 50 mg/kg ephedrine with 15 or 30 mg/kg caffeine. Cardiotoxic lesions occurred in 47% of animals in the 25 mg/kg ephedrine groups with caffeine at 7.25, 15, or 30 mg/kg. There was no statistical difference in the occurrence of cardiotoxic lesions when 15 or 30 mg/kg caffeine was combined with Ma Huang equivalent to 25 or 50 mg/kg ephedrine; likewise there was no statistical difference in the occurrence of cardiotoxic lesions when 7.25, 15, or 30 mg/kg caffeine was combined with 25 mg/kg ephedrine. These results show that the cardiotoxic effects of the herbal medicine, Ma Huang, are similar to that of ephedrine, the principal active ingredient in the herbal medicine. The combination of Ma Huang or ephedrine with caffeine enhanced the cardiotoxicity over that with the herbal medicine or the active ingredient alone. (+info)A case of ischemic colitis associated with the herbal food supplement ma huang. (8/9)
(+info)Ephedra sinica, also known as Ma Huang, is a plant that has been used in traditional Chinese medicine for thousands of years. It contains several alkaloids, including ephedrine and pseudoephedrine, which have stimulant effects on the central nervous system and cardiovascular system.
Ephedra sinica has been used to treat various medical conditions such as asthma, bronchitis, and nasal congestion. However, its use as a dietary supplement or weight loss aid has been controversial due to concerns about its safety. The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedra in 2004 due to the risk of serious adverse effects, including heart attack, stroke, and death.
It is important to note that Ephedra sinica should only be used under the supervision of a qualified healthcare professional, as it can interact with other medications and have potentially dangerous side effects.
Ephedra is a genus of plants that contain various alkaloids, including ephedrine and pseudoephedrine. These plants, also known as "joint-fir" or "Mormon tea," have been used in traditional medicine for thousands of years to treat various conditions such as asthma, nasal congestion, and hay fever.
Ephedra has been used as a stimulant to increase energy, alertness, and physical performance. However, the use of ephedra-containing supplements has been linked to serious side effects, including heart attack, stroke, and death, particularly when taken in high doses or combined with other stimulants. As a result, the sale of dietary supplements containing ephedrine alkaloids was banned in the United States in 2004.
It's important to note that while ephedra has been used in traditional medicine, its safety and effectiveness have not been thoroughly studied in clinical trials, and its use is not recommended without medical supervision.
Ephedrine is a medication that stimulates the nervous system and is used to treat low blood pressure, asthma, and nasal congestion. It works by narrowing the blood vessels and increasing heart rate, which can help to increase blood pressure and open up the airways in the lungs. Ephedrine may also be used as a bronchodilator to treat COPD (chronic obstructive pulmonary disease).
Ephedrine is available in various forms, including tablets, capsules, and solutions for injection. It is important to follow the instructions of a healthcare provider when taking ephedrine, as it can have side effects such as rapid heart rate, anxiety, headache, and dizziness. Ephedrine should not be used by people with certain medical conditions, such as heart disease, high blood pressure, or narrow-angle glaucoma, and it should not be taken during pregnancy or breastfeeding without consulting a healthcare provider.
In addition to its medical uses, ephedrine has been used as a performance-enhancing drug and is banned by many sports organizations. It can also be found in some over-the-counter cold and allergy medications, although these products are required to carry warnings about the potential for misuse and addiction.
I'm sorry for any confusion, but "Caragana" is not a medical term or concept. It is actually the name of a genus of flowering plants in the legume family, also known as Siberian peashrubs. These plants are often used in landscaping and erosion control due to their hardiness and ability to fix nitrogen in the soil. If you have any questions related to medicine or health, I would be happy to try to help answer them for you!
I am not aware of a specific medical definition for the term "China." Generally, it is used to refer to:
1. The People's Republic of China (PRC), which is a country in East Asia. It is the most populous country in the world and the fourth largest by geographical area. Its capital city is Beijing.
2. In a historical context, "China" was used to refer to various dynasties and empires that existed in East Asia over thousands of years. The term "Middle Kingdom" or "Zhongguo" (中国) has been used by the Chinese people to refer to their country for centuries.
3. In a more general sense, "China" can also be used to describe products or goods that originate from or are associated with the People's Republic of China.
If you have a specific context in which you encountered the term "China" related to medicine, please provide it so I can give a more accurate response.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
I'm sorry for any confusion, but "Mongolia" is not a medical term. It is the name of a country located in Central Asia. If you have any questions about medical conditions or terminology, I would be happy to help clarify those for you.
I'm sorry for any confusion, but "Russia" is not a medical term or concept. Russia is the largest country in the world by land area, located primarily in Asia with a smaller portion extending into Europe. It is a nation rich in history and culture, known for its diverse landscapes, from tundra and forests to subtropical beaches.
If you have any medical questions or terms that you would like me to define, please feel free to ask!
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Huang7
- It is the primary source of the medicinal preparation ephedra, also known by its Chinese name ma huang. (wikipedia.org)
- Ephedra sinica , also known as Ma Huang. (researchgate.net)
- The Chinese botanical ephedra, or ma-huang, is sold as a dietary supplement in the United States. (nih.gov)
- Dietary supplements that contain ephedra alkaloids (sometimes called ma huang) are widely promoted and used in the United States as a means of losing weight and increasing energy. (nih.gov)
- FAMILY: Ephedraceae GENUS: Ephedra SPECIES: Sinica COMMON NAMES: Ask-for-trouble, Chinese Ephedra, Chinese Joint Fir, Chinesisches Meertraubel, Ma-huang, Ts'ao Ma-huang Ephedra sinica is a perennial horsetail plant which can grow up to 75 cm in height. (entheology.com)
- The Ephedra (Ephedra Sinica or Ma Huang) Plant originated in China, and has been around for 1000's of years. (mysupplementstore.com)
- The assign ephedra (ma huang) contains multiple chemical compounds, but the most pre-eminent is ephedrine. (estranky.cz)
Stapf2
Ephedraceae4
- [3] Ang Ephedra sinica sakop sa kahenera nga Ephedra , ug kabanay nga Ephedraceae . (wikipedia.org)
- Premise of the Study Ephedra sinica (Ephedraceae) is a gymnosperm shrub with a wide distribution across Central and Eastern Asia. (bibbase.org)
- article{jiao_development_2019, title = {Development of novel {EST}-{SSR} markers for {Ephedra} sinica ({Ephedraceae}) by transcriptome database mining}, volume = {7}, issn = {2168-0450}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/aps3.1212}, doi = {10.1002/aps3.1212}, abstract = {Premise of the Study Ephedra sinica (Ephedraceae) is a gymnosperm shrub with a wide distribution across Central and Eastern Asia. (bibbase.org)
- Ephedra is one of the largest genera of the Ephedraceae family, which is distributed in arid and semiarid regions of the world. (herbconer.com)
Species12
- Cross-species amplifications were successfully conducted with two related Ephedra species for all 11 di- or trinucleotide simple sequence repeats. (bibbase.org)
- Other Ephedra species with similar medicinal properties to ephedra grow throughout the northern hemisphere. (herbsandremedies.club)
- In North America, related species were used to treat fevers and relieve kidney pain, while in India, Ephedra species were taken for asthma, hay fever, and rheumatism. (herbsandremedies.club)
- North American ephedra species, such as E. nevadensis (known as Mormon tea), contain little or no ephedrine or other alkaloids [ 10 ]. (nih.gov)
- Ephedra is best Grown in Rocky Deserts and Mountains, Beverages Made from Ephedra named as Yellow River, Mormom Tea, Whorehouse Tea, there are 10 Species in North America, and is Planted in Early Spring! (mysupplementstore.com)
- about the possible interactions between herbal ephedra and biologically active compounds in the other plant species that are constituents of many dietary supplements. (nih.gov)
- Ephedrine is a natural alkaloid obtained from ephedra species like ephedra sinica and ephedra officialis. (egpat.com)
- It is usually found in other species such as Ephedra sinica. (herbconer.com)
- Whereas other species contain ephedrine, ephedra nevadensis does not contain ephedrine. (herbconer.com)
- Yoh should therefore be careful when othering for Mormon tea, lest you'd be served Ephedra tea, which are likely made from other Ephedra species, instead of Mormon tea. (herbconer.com)
- Ephedra nevadensis (Nevada Ephedra) is an American species of Ephedra that can be found in dry areas of western North America. (ndgbotanicals.com)
- This is why this species of Ephedra commonly gets the name Mormon Tea. (ndgbotanicals.com)
Shrub4
- Ephedra is a low evergreen shrub with small scaly leaves. (nih.gov)
- Ephedra pachyclada is an evergreen Shrub. (pfaf.org)
- Ephedra is an evergreen shrub-like plant native to Central Asia and Mongolia. (livingwellmagazine.net)
- The medical history of amphetamine-like compounds extends back over a century, beginning with the identification of ephedrine as the active ingredient in extracts from the Ephedra sinica shrub, which had long been used in traditional Chinese and Indian medicine. (medscape.com)
Pseudoephedrine1
- [ 4 ] The major active chemicals found in ephedra are ephedrine and pseudoephedrine, which act as sympathomimetic agonists. (medscape.com)
Medicinal3
- The Ephedra Plant offers many medicinal benefits besides weight loss, by raising your metabolism and heart rate. (mysupplementstore.com)
- The most frequently mentioned medicinal herb was Ephedra sinica (7 cases) and the most commonly reported AEs were abdominal pain (8 cases), dizziness (6 cases), diarrhea (5 cases), and vomiting (5 cases) were followed in order. (jkom.org)
- The extract form Ephedra has been used in China for medicinal purposes for several thousand years. (ncats.io)
Genus4
- Chinese medicine Ephedra (the genus of plants) Ephedra (US-specific page on ephedrine-containing dietary supplements, observed (negative) health effects of these, and corresponding regulatory actions toward them) List of herbs with known adverse effects Bell, A. & Bachman, S. (2011). (wikipedia.org)
- However, in some instances, mormon tea commercialized products are being adulterated by other Ephedra genus plants, which contain Ephedrine. (herbconer.com)
- Be careful to read each label to see if the product is of other Ephedra genus plants or purely Ephedra nevadensis. (herbconer.com)
- Although Ephedra nevadensis is from the same genus as Ephedra sinica and Ephedra major, it does not contain the chemical ephedrine. (ndgbotanicals.com)
Alkaloids8
- The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedrine alkaloids (stimulant compounds found in Ephedra sinica and some other plants) in the United States in 2004. (nih.gov)
- This document summarizes the results of an evidence-based review on the efficacy and safety of ephedra and ephedrine alkaloids for weight loss or to enhance athletic performance (power and endurance). (nih.gov)
- The FDA requested an independent review of reports of adverse events related to the use of supplements that contained ephedra alkaloids to assess causation and to estimate the level of risk the use of these supplements poses to consumers. (nih.gov)
- We reviewed 140 reports of adverse events related to the use of dietary supplements containing ephedra alkaloids that were submitted to the FDA between June 1, 1997, and March 31, 1999. (nih.gov)
- Thirty-one percent of cases were considered to be definitely or probably related to the use of supplements containing ephedra alkaloids, and 31 percent were deemed to be possibly related. (nih.gov)
- Among the adverse events that were deemed definitely, probably, or possibly related to the use of supplements containing ephedra alkaloids, 47 percent involved cardiovascular symptoms and 18 percent involved the central nervous system. (nih.gov)
- Dietary supplements containing ephedrine alkaloids from herbal sources (ephedra) are brought to the attention of the CSWG as part of an ongoing National Institutes of Health (NIH) Office of Dietary Supplements (ODS) research initiative on the safety and efficacy of these products. (nih.gov)
- Some agents, often components of herbal preparations at far greater concentrations than the ephedrine alkaloids, may profoundly influence the toxicity attributed to ephedra supplements. (nih.gov)
Alkaloid4
- The pharmacologic activity of an ephedra sample depends on its alkaloid composition. (nih.gov)
- For patients with a history of benign prostate hyperplasia, the author will first consult the Chinese Medicine team to establish whether any herbal medicine has the ingredient ephedra alkaloid (麻黃). (hkmj.org)
- Concern that naturally occurring non-ephedrine alkaloid constituents of Ephedra spp. (nih.gov)
- Ephedrine (l-form) is an alkaloid, which was initially purified from Ephedra plant. (ncats.io)
Chromium picolinate1
- Ephedra-containing performance enhancers often contain caffeine and other ingredients, such as chromium picolinate or l -carnitine, and may be consumed with other performance enhancers, such as androstenedione and creatine monohydrate. (nih.gov)
Seeds2
- In traditional medicines also, Ephedra roots, stem bark, leaves, and even seeds are being used to make infusions for treating kidney diseases. (herbconer.com)
- Once mature, Ephedra nevadensis will begin to produce clusters of yellow flowers that will eventually lead to the development of small cones that contain the seeds. (ndgbotanicals.com)
Extract3
- Yes, Ephedra Extract is legal. (mysupplementstore.com)
- The Ephedra Extract contained in popular weight loss supplements like ECA Xtreme, Stimerex ES, and Lipodrene is legal. (mysupplementstore.com)
- Ephedra Extract is very effective as a fat burner and appetite suppressant and can be legally purchased online and in stores with having to provide identification. (mysupplementstore.com)
Toxicity1
- Between 1995 and 1997, the FDA received more than 900 reports of possible ephedra toxicity. (livingwellmagazine.net)
Botanical1
- Although this analysis raises concerns about the safety of botanical dietary supplements containing ephedra, most of these case reports are not documented sufficiently to support an informed judgment about the relationship between the use of ephedra-containing dietary supplements or ephedrine and the adverse event in question. (nih.gov)
Nevadensis4
- Mormon tea, also known as Brigham tea, is a herbal drink that's made from the herbal tree, Ephedra nevadensis. (herbconer.com)
- Mormon tea are made from branches of Ephedra nevadensis. (herbconer.com)
- Beyond using ephedra nevadensis as for tea, people also use it as a beverage and herbal mixture. (herbconer.com)
- A tea made with Ephedra nevadensis was commonly used medicinally by the Mormons. (ndgbotanicals.com)
Intermedia1
- Ephedra sinica, Ephedra equisentina, and Ephedra intermedia [ 2 ]. (nih.gov)
Herb3
- Ephedra is an herb and Chinese folk medicine with evidence for weight loss, but owing to concerns about adverse health effects, including cardiovascular, psychiatric, and neurologic consequences, it was banned by the US Food and Drug Administration (FDA) in 2004. (medscape.com)
- Ephedra is a strongly stimulant, acrid-tasting herb that has a central place in Chinese and other herbal traditions. (herbsandremedies.club)
- Ephedra has been banned in the U.S. due to frequent abuse of the herb, as an amphetamine-type "high" and, at excessive dosage, in weight-loss regimens. (herbsandremedies.club)
Dietary supplements10
- Prior to the ban, ephedra was an ingredient in some dietary supplements promoted for weight loss, increased energy, and enhanced athletic performance. (nih.gov)
- Almost no new research on ephedra has been performed in the years since its use in dietary supplements was banned in the United States. (nih.gov)
- Prior to the ban, research showed that dietary supplements containing ephedra/ephedrine (usually in combination with caffeine) had modest short-term effects on weight loss. (nih.gov)
- The use of ephedrine, ephedrine plus caffeine, or dietary supplements containing ephedra and botanicals with caffeine is associated with a modest but statistically significant increase in weight loss over a relatively short time (less than or equal to 6 months). (nih.gov)
- No studies have assessed the effect of dietary supplements containing ephedra and botanicals on athletic performance. (nih.gov)
- RAND analyzed adverse event reports filed with the U.S. Food and Drug Administration (FDA) and with a manufacturer of ephedra-containing dietary supplements as well as published case reports. (nih.gov)
- In 2004, the FDA banned the U.S. sale of dietary supplements containing ephedra. (livingwellmagazine.net)
- Ephedra use may lead to serious health problems when used with other dietary supplements or medicines. (livingwellmagazine.net)
- As the Senate Committee noted, the number of Americans taking dietary supplements containing ephedra has risen dramatically. (nih.gov)
- Dr. Paul Coates, Director of the NIH Office of Dietary Supplements, provided information on existing studies of ephedra. (nih.gov)
Stems1
- Chemical constituents of the stems of Ephedra sinica. (hkmj.org)
Stimulant1
- Constitution End-piece Products inaugurate containing caffeine and ephedra/ephedrine were inaugurate to be more efficient in compensation Power Escape and Energy Boosting then Just Ma Haung by Itself, The Consummate ‚lan Stimulant Combo Ephedra & Caffeine. (estranky.cz)
Plant1
- An ointment made from Ephedra plant may be applied topically as well, to hasten the time it would take to complete wound closure. (herbconer.com)
Supplements7
- In 2004, the FDA banned the use of ephedra in nutritional supplements and the composition of Hydroxycut was altered, with removal of ephedra. (nih.gov)
- You might remember that in 2004, the FDA actually banned ephedra-containing dietary and performance-enhancing supplements. (theconversation.com)
- Ban against ephedra supplements at any does upheld. (vitanetonline.com)
- Can I Stack Ephedra With Other Weight Loss Supplements? (mysupplementstore.com)
- Ephedra can be stacked with other weight loss supplements like Hi-Tech CLA, As long as the product you are stacking with ephedra doesn't contain stimulants, you will be fine. (mysupplementstore.com)
- The products listed are the most popular stacking partners for ephedra weight loss supplements. (mysupplementstore.com)
- The nomination of ephedra containing supplements to the National Toxicology Program (NTP) is part of the expanded effort by the ODS. (nih.gov)
Rarely gives rise to side effects1
- At therapeutic dosage, and with professional guidance, ephedra rarely gives rise to side effects. (herbsandremedies.club)
Caffeine and ephedra1
- Initial ingredients in the products included caffeine and ephedra which in animal studies led to weight loss. (nih.gov)
Athletic performance1
- Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis. (nih.gov)
Asthma4
- Today, ephedra is used in the West and in China for problems ranging from chills and fevers to asthma and hay fever. (herbsandremedies.club)
- Ephedra is used principally in current Western herbal medicine as a treatment for asthma and hay fever, and for the acute onset of colds and flu. (herbsandremedies.club)
- Ephedra does not cure asthma but in many cases it is very effective in treating the symptoms and thus making life somewhat easier for the sufferer. (pfaf.org)
- What Ephedra Is Used For Ephedra has been used for more than 5,000 years in China and India to treat conditions such as colds, fever, flu, headaches, asthma, wheezing, and nasal congestion. (livingwellmagazine.net)
Found7
- Ephedra has been found to activate beta-adrenergic receptors and stimulate thermogenesis in brown adipose tissue, resulting in weight loss. (medscape.com)
- [ 8 ] Ephedra has been commonly found in combination with caffeine and aspirin, which appear to acts synergistically with ephedra to enhance weight loss. (medscape.com)
- Before the FDA's 2004 ban of ephedra, a review published in JAMA [ 10 ] found that ephedra was associated with modest, short-term weight loss averaging 0.9 kg/mo. (medscape.com)
- An NCCAM-funded study that analyzed phone calls to poison control centers found a higher rate of side effects from ephedra, compared with other herbal products. (livingwellmagazine.net)
- Other studies and systematic reviews have found an increased risk of heart, psychiatric, and gastrointestinal problems, as well as high blood pressure and stroke, with ephedra use. (livingwellmagazine.net)
- A phenethylamine found in EPHEDRA SINICA. (bvsalud.org)
- What Other Ingredients Are Commonly Found In Ephedra Products & Stacks? (mysupplementstore.com)
Diuretics2
- My Supplement Store sells energy drinks and gels, fat burners, diuretics, and ephedra products. (mysupplementstore.com)
- Ephedra-based diet aids often contain other stimulants, such as caffeine (guarana), as well as salicin, diuretics, and cathartics. (nih.gov)
Stimulants1
- People with a history of cardiovascular disease, those taking high doses of ephedra, and those taking it in combination with other stimulants such as caffeine would be expected to be at increased risk, but some of the severe events occurred in people with no preexisting medical problems, people taking relatively low doses of ephedra, or people taking ephedra alone. (nih.gov)
Botanicals1
- Results of controlled trials show that the use of synthetic ephedrine, ephedrine plus caffeine, or ephedra plus botanicals containing caffeine is associated with 2-3 times the risk of nausea, vomiting, psychiatric symptoms such as anxiety and change in mood, autonomic hyperactivity, and palpitations compared with placebo. (nih.gov)
Products7
- According to the RAND report, the number of deaths, myocardial infarctions, cerebrovascular accidents, seizures, and serious psychiatric illnesses in young adults is sufficient to warrant further evaluation of the safety of these products in a controlled manner (such as a hypothesis-testing case-control study) to test the possibility that consumption of ephedra or ephedrine causes these serious adverse events. (nih.gov)
- In 2004, Hydroxycut products containing ephedra were withdrawn from use in the United States because of cardiovascular risks and in 2009 because of hepatotoxicity. (nih.gov)
- Although evidence of modest weight loss secondary to ephedra-caffeine ingestion exists, potentially serious adverse effects have led the U.S. Food and Drug Administration to ban the sale of these products. (aafp.org)
- Products containing ephedra should be taken about 1 hour before meals and workouts. (mysupplementstore.com)
- We currently offer 11 ephedra products. (mysupplementstore.com)
- Both men and women can take ephedra products. (mysupplementstore.com)
- Ephedra is an effective stand-alone weight loss supplement, but when combined with other products its effectiveness works even more efficiently. (mysupplementstore.com)
Cardiovascular disease1
- Using ephedra may worsen many health conditions such as cardiovascular disease, kidney disease, and diabetes. (livingwellmagazine.net)
China2
- Native to northern China and Inner Mongolia, ephedra often grows in desert areas. (herbsandremedies.club)
- In China, ephedra is popular for chills and fevers, coughs and wheezing, and in combination with rehmannia (Rehmannia glutinosa) it is given to treat kidney yin deficiency. (herbsandremedies.club)
Efficacy1
- Although ephedra has had some efficacy as a nutraceutical weight-loss agent, at least in the short term, it is not considered safe and therefore should not be recommended to patients as an aid to weight loss. (medscape.com)
Mormon1
- So be careful not to confuse Mormon tea with ephedra drink. (herbconer.com)
Combination2
- Caffeine has been shown to have a synergistic effect on weight loss when used in combination with either ephedra or polyphenols. (medscape.com)
- 4 Metabolife 356, an ephedra-containing combination supplement, was the top-selling diet supplement with $70 million in sales, representing a 127 percent increase from sales in 2000. (aafp.org)
Potentially serious1
- Combining ephedra with caffeine increases the risk of potentially serious side effects. (livingwellmagazine.net)
Long1
- Ephedra may be effective in promoting weight loss when taken for up to 6 months, however it's unclear whether this benefit will continue long-term. (pharmachoice.com)
Weight1
- In addition to its synergistic effect with polyphenols and ephedra, caffeine may play a role in weight loss through indirect mechanisms. (medscape.com)