Esophagus
Dissecting intramural haematoma of the oesophagus. (1/408)
The largest series of patients (n = 10) with dissecting intramural haematoma of the oesophagus is described. The typical features, chest pain with odynophagia or dysphagia and minor haematemesis are usually present but not always elicited at presentation. If elicited, these symptoms should suggest the diagnosis and avoid mistaken attribution to a cardiac origin for the pain. Precipitating factors such as a forced Valsalva manoeuvre cannot be identified in at least half the cases. Early endoscopy is safe, and confirms the diagnosis when an haematoma within the oesophageal wall or the later appearances of a longitudinal ulcer are seen. Dissecting intramural haematoma of the oesophagus has an excellent prognosis when managed conservatively. (+info)Intraepithelial haemorrhage of the oesophagus: a terminal event in haematological disorders. (2/408)
AIMS: To investigate the clinicopathological findings in cases with intraepithelial haemorrhage of the oesophagus (IHO). METHODS: Necropsy records and the histopathology findings in the oesophagus were reviewed for the period 1990 to 1995. Six cases (0.7%) of IHO were found among 919 necropsy cases. Clinical records of these patients and gross and microscopic slides were reviewed in detail. RESULTS: The ages of the IHO cases ranged from 42 to 82 years (average 68 years), with a male to female ratio of 1:2. All cases had underlying haematological disorders with thrombocytopenia, but disseminated intravascular coagulation was not evident in any case. Macroscopically, solitary (two cases) or multiple (four cases) haemorrhagic lesions ranging from 6 to 79 mm in size were identified within the distal oesophagus. Microscopically, there was no inflammatory infiltration, destruction of red blood cells, or submucosal scar formation. CONCLUSIONS: IHO seems to occur shortly before death as a terminal event in haematological disorders. Based on these observations, the term "terminal IHO" can be suggested for this type of oesophageal lesion. (+info)Assessment of therapeutic response of oropharyngeal and esophageal candidiasis in AIDS with use of a new clinical scoring system: studies with D0870. (3/408)
We developed and compared five scoring systems designed to quantitate therapeutic response in cases of oropharyngeal candidiasis. We utilized prospectively collected data on 114 patients treated with several doses of the azole D0870. Patients were infected with fluconazole-susceptible (n = 49) or -resistant organisms (MIC, > or = 16 mg/mL; n = 61). Patients with fluconazole resistance had lower CD4+ cell counts at baseline; more symptoms (P = .0006); a higher frequency of dysgeusia (P = .004), dysphagia (P = .006), and throat pain (P = .0034); and greater oral coverage by plaques of Candida. There was no difference between the two groups in terms of colony-forming units, and any change did not correlate with response to therapy. Resolution of dysphagia (P < .01) and oral pain (P < .01) correlated well with response to therapy, unlike retrosternal pain and throat pain, which were also less frequent. Xerostomia, a "furry" taste, and dysgeusia were frequent nonspecific symptoms. Scoring system C, weighting resolution of a symptom higher than absence of a symptom at baseline, yielded the best correlation with global outcome (r = 0.86) and allows the quantitation of incomplete but clinically beneficial responses to therapy. (+info)Evaluating diagnosis and treatment of oral and esophageal candidiasis in Ugandan AIDS patients. (4/408)
A randomized cross-over clinical and endoscopic evaluation of 85 Ugandan patients showed that esophageal candidiasis in AIDS patients with oral candidiasis could be managed without endoscopy and biopsies. Oral lesions, especially when accompanied by esophageal symptoms, were sufficient for diagnosis. Miconazole was more effective than nystatin in treating esophageal candidiasis and could be a valid alternative to more expensive azolic drugs in developing countries. (+info)Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions. (5/408)
In order to characterize p53 alterations in esophageal cancer and to study their roles in carcinogenesis, we performed gene mutation and immunohistochemical analysis on 43 surgically resected human esophageal specimens, which contain squamous cell carcinoma (SCC) and adjacent non-cancerous lesions, from a high-incidence area of Linzhou in Henan, China. A newly developed immunohisto-selective sequencing (IHSS) method was used to enrich the p53 immunostain-positive cells for mutation analysis. p53 gene mutations were detected in 30 out of 43 (70%) SCC cases. Among 29 SCC cases that were stained positive for p53 protein, 25 (86%) were found to contain p53 mutations. In five cases of SCC with homogeneous p53 staining, the same mutation was observed in samples taken from four different positions of each tumor. In a well differentiated cancer nest, p53 mutation was detected in only the peripheral p53-positive cells. In tumor areas with heterogeneous p53 staining, either the area stained positive for p53 had an additional mutation to the negatively stained area or both areas lacked any detectable p53 mutation. In the p53-positive non-cancerous lesions adjacent to cancer, p53 mutations were detected in seven out of 16 (47%) samples with basal cell hyperplasia (BCH), eight out of 12 (67%) samples with dysplasia (DYS), and six out of seven (86%) samples with carcinoma in situ (CIS). All mutations found in lesions with DYS and CIS were the same as those in the nearby SCC. In seven cases of BCH containing mutations, only three had the same mutations as the nearby SCC. The results suggest that p53 mutation is an early event in esophageal carcinogenesis occurring in most of the DYS and CIS lesions, and cells with such mutations will progress to carcinoma, whereas the role of p53 mutations in BCH is less clear. (+info)Hypothesis: the changing relationships of Helicobacter pylori and humans: implications for health and disease. (6/408)
Helicobacter pylori has apparently colonized the human stomach since time immemorial and is superbly adapted for persistence. Several genotypes, including cag+, are associated with increased risk of gastric and duodenal diseases. With modern life, for probably the first time in human history, there are large numbers of noncolonized persons. Duodenal ulceration has been present essentially for only 200 years; that its incidence rose just as H. pylori was waning is best explained by changes in gastric microecology. As H. pylori is disappearing, duodenal ulceration and gastric cancer rates are falling. However, more proximal diseases, gastroesophageal reflux (GERD), Barrett's esophagus, and adenocarcinomas of the gastric cardia and lower esophagus, are increasing; colonization with cag+ H. pylori strains appears protective against these diseases. Thus, in the 21st century, the continuing decline in H. pylori may lead to the disappearance of duodenal ulcers and distal gastric cancers and toward a marked increase in GERD, Barrett's esophagus, and esophageal adenocarcinoma. (+info)Boerhaave's syndrome presenting as tension pneumothorax. (7/408)
Boerhaave's syndrome can present initially as a case of tension pneumothorax. Mortality rate with delayed treatment is very high, therefore diagnosis should be made rapidly in the emergency department. Multidisciplinary cooperation, immediate radiological confirmation, prompt aggressive resuscitation, and surgical intervention offer the best chance of survival. (+info)Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. (8/408)
A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV). Twenty-four HIV-infected patients with biopsy-confirmed aphthous ulceration of the esophagus were randomly assigned to receive either oral thalidomide, 200 mg/day, or oral placebo daily for 4 weeks. Eight (73%) of 11 patients randomized to receive thalidomide had complete healing of aphthous ulcers at the 4-week endoscopic evaluation, compared with 3 (23%) of 13 placebo-randomized patients (odds ratio, 13.82; 95% confidence interval, 1.16-823.75; P=.033). Odynophagia and impaired eating ability caused by esophageal aphthae were improved markedly by thalidomide treatment. Adverse events among patients receiving thalidomide included somnolence (4 patients), rash (2 patients), and peripheral sensory neuropathy (3 patients). Thalidomide is effective in healing aphthous ulceration of the esophagus in patients infected with HIV. (+info)Esophageal diseases refer to a range of medical conditions that affect the esophagus, which is the muscular tube that connects the throat to the stomach. Here are some common esophageal diseases with their brief definitions:
1. Gastroesophageal reflux disease (GERD): A chronic condition in which stomach acid or bile flows back into the esophagus, causing symptoms such as heartburn, chest pain, and difficulty swallowing.
2. Esophagitis: Inflammation of the esophageal lining, often caused by GERD, infection, or medication.
3. Esophageal stricture: Narrowing of the esophagus due to scarring or inflammation, which can make swallowing difficult.
4. Esophageal cancer: Cancer that forms in the tissues of the esophagus, often as a result of long-term GERD or smoking.
5. Esophageal motility disorders: Disorders that affect the normal movement and function of the esophagus, such as achalasia, diffuse spasm, and nutcracker esophagus.
6. Barrett's esophagus: A condition in which the lining of the lower esophagus changes, increasing the risk of esophageal cancer.
7. Esophageal diverticula: Small pouches that form in the esophageal wall, often causing difficulty swallowing or regurgitation.
8. Eosinophilic esophagitis (EoE): A chronic immune-mediated disorder characterized by inflammation of the esophagus due to an allergic reaction.
These are some of the common esophageal diseases, and their diagnosis and treatment may vary depending on the severity and underlying cause of the condition.
The esophagus is the muscular tube that connects the throat (pharynx) to the stomach. It is located in the midline of the neck and chest, passing through the diaphragm to enter the abdomen and join the stomach. The main function of the esophagus is to transport food and liquids from the mouth to the stomach for digestion.
The esophagus has a few distinct parts: the upper esophageal sphincter (a ring of muscle that separates the esophagus from the throat), the middle esophagus, and the lower esophageal sphincter (another ring of muscle that separates the esophagus from the stomach). The lower esophageal sphincter relaxes to allow food and liquids to enter the stomach and then contracts to prevent stomach contents from flowing back into the esophagus.
The walls of the esophagus are made up of several layers, including mucosa (a moist tissue that lines the inside of the tube), submucosa (a layer of connective tissue), muscle (both voluntary and involuntary types), and adventitia (an outer layer of connective tissue).
Common conditions affecting the esophagus include gastroesophageal reflux disease (GERD), Barrett's esophagus, esophageal cancer, esophageal strictures, and eosinophilic esophagitis.
Esophageal neoplasms refer to abnormal growths in the tissue of the esophagus, which is the muscular tube that connects the throat to the stomach. These growths can be benign (non-cancerous) or malignant (cancerous). Malignant esophageal neoplasms are typically classified as either squamous cell carcinomas or adenocarcinomas, depending on the type of cell from which they originate.
Esophageal cancer is a serious and often life-threatening condition that can cause symptoms such as difficulty swallowing, chest pain, weight loss, and coughing. Risk factors for esophageal neoplasms include smoking, heavy alcohol consumption, gastroesophageal reflux disease (GERD), and Barrett's esophagus. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Esophageal disease
Esophageal intramural pseudodiverticulosis
Esophageal stricture
Acid perfusion test
Canadian Light Source
Esophageal stent
Tannerella forsythia
Gastroesophageal reflux disease
Deaths in April 2020
Coffee ground vomiting
Glycogenic acanthosis
Oropharyngeal dysphagia
Pemphigoid
Sandifer syndrome
Melatonin as a medication and supplement
Pink lady (medicine)
Gastrointestinal bleeding
Esophageal rupture
IgG4-related disease
Helicobacter pylori
Peptidoglycan recognition protein 2
Gastrointestinal disease
Oral manifestations of systemic disease
Laser surgery
Therapeutic endoscopy
Xerostomia
Trefoil factor 3
Esophageal cancer
Guillermo J. Tearney
Leukoplakia
Esophageal disease - Wikipedia
Gastro-oesophageal reflux disease
Gastroesophageal Reflux Disease Workup: Approach Considerations, Upper Gastrointestinal Endoscopy, Esophageal Manometry
Esophageal Diseases | NewYork-Presbyterian
Esophageal Cancer Treatment Protocols: Overview, General Recommendations Based on Stage, Neoadjuvant Chemotherapy and...
Guideline on screening for esophageal adenocarcinoma in patients with chronic gastroesophageal reflux disease | CMAJ
Screening pre-bariatric surgery patients for esophageal disease with esophageal capsule endoscopy
GERD (Gastro-Esophageal Reflux Disease) | www.justmommies.com
Systematic review: ageing and gastro-oesophageal reflux disease symptoms, oesophageal function and reflux oesophagitis
Key priorities for implementation | Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management |...
British Library EThOS: A study of the pathophysiology of gastro-oesophageal reflux disease
CPD: Gastro-oesophageal reflux disease (GORD) in adults | Nursing in Practice
Prevalence of Campylobacter-like Organisms in Patients with Gastro-Esophageal Reflux Disease Versus Normals - Helico
An Unusual Variation of Oesophageal Atresia | Archives of Disease in Childhood
The association between gastro-oesophageal reflux disease and asthma: a systematic review | Gut
Esophageal Cancer Treatment Protocols: Overview, General Recommendations Based on Stage, Neoadjuvant Chemotherapy and...
The Effect of Monocyte Count on Disease-Free Survival in Esophageal Cancer Patients | Research Square
Gastro-oesophageal reflux in infants under 6 months with cystic fibrosis | Archives of Disease in Childhood
The surgeon's perspective on oesophageal disease, and what it means to pathologists | Journal of Clinical Pathology
Gastro esophageal Reflux Disease Archives - Dental News
HASHMICLINIC - Homeopathy & Acupuncture - Prof. Dr. Rifat Hashmi - Infertility - Gasto oesophageal reflux disease -Homeopathic...
HASHMICLINIC - Homeopathy & Acupuncture - Prof. Dr. Rifat Hashmi - Lung cancer - Gasto oesophageal reflux disease -Homeopathic ...
Protonix Generic, Cheap protonix pharmacy :: Living with Reflux | Gastro-oesophageal Reflux Disease Birmingham
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Esophageal disease | HonorHealth
ESOPHAGEAL DISEASES / - ISBN: 9781904392552
Esophageal Diverticula | Diseases and Disorders
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Gastrointestinal System - Gastroesophageal/Gastro-oesophageal Reflux Disease (GERD/GORD) - Related Tools & Resources
Gastro-Esophag3
- Gastro-Esophageal Reflux Disease or better known as just 'reflux' or 'GERD' is when the contents of the stomach start pushing or splashing back up the esophagus or into the nose and throat. (justmommies.com)
- Endoscopy and biopsy findings in gastro-esophageal reflux disease and the possible consequences of exogenous chemical damage and foreign body ingestion are highlighted. (uaeu.ac.ae)
- 05. PCL = PTSD Symptom Checklist, LRS = lower respiratory symptoms, GERD = gastro-esophageal reflux disease. (cdc.gov)
GERD24
- EGD also excludes the presence of other diseases (eg, peptic ulcer) that can present similarly to GERD. (medscape.com)
- Although delayed gastric emptying is present in as many as 60% of patients with GERD, this emptying defect is usually a minor factor in the pathogenesis of the disease in most patients (except in patients with advanced diabetes mellitus or connective tissue disorders). (medscape.com)
- Some esophageal disorders, such as GERD and eosinophilic esophagitis, may improve with changes in diet. (nyp.org)
- When lifestyle changes and medications are not effective enough to treat an esophageal disorder, our skilled surgeons use minimally invasive approaches whenever possible to treat esophageal cancer (including removal of the esophagus, or esophagectomy), achalasia, and GERD - operating through smaller incisions, and sometimes robotically. (nyp.org)
- The Canadian Task Force on Preventive Health Care recommends not screening adults with chronic gastroesophageal reflux disease (GERD) for esophageal adenocarcinoma and precursor conditions (Barrett esophagus or dysplasia), because there is an absence of evidence for benefit, and there are uncertain harms, important resource implications and variable patient values and preferences. (cmaj.ca)
- A single retrospective cohort study (very low-certainty evidence) found that screening patients with chronic GERD identified more cases with esophageal adenocarcinoma at an early stage, but found no difference in long-term survival (all-cause mortality). (cmaj.ca)
- Gastro-oesophageal reflux disease (GERD) is thought to become more prevalent with age. (nih.gov)
- To assess systematically how age affects the prevalence of GERD and its oesophageal complications. (nih.gov)
- Systematic PubMed searches were used to identify population-based studies on the age-related prevalence and incidence of GERD, and clinical studies on age-related changes in oesophageal complications in GERD. (nih.gov)
- Clinical studies in patients with GERD showed an increase in reflux oesophagitis severity and a decrease in heartburn severity with age, and age-related increases in oesophageal acid exposure and anatomical disruption of the gastro-oesophageal junction. (nih.gov)
- Gastro-oesophageal reflux disease (GERD) has become the most important oesophageal issue of the 21st century. (bmj.com)
- 6 Oesophageal adenocarcinoma primarily affects white men with GERD, while squamous cell carcinoma is more commonly associated with tobacco and alcohol use. (bmj.com)
- 3 , 7-10 GERD is a prevalent disease affecting nearly one-quarter of Americans and Barrett's oesophagus is a known complication of GERD. (bmj.com)
- 11 , 12 We know that chronic GERD leads to Barrett's oesophagus, which is a precursor to oesophageal adenocarcinoma. (bmj.com)
- Gastroesophageal reflux disease (GERD) happens when a muscle at the end of your esophagus does not close properly. (teach2reachpjtshop.com)
- Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the tube connecting your mouth and stomach (esophagus). (rheumatology-now.com)
- Registered Dietician, discusses gastroesophageal reflux disease (GERD). (rheumatology-now.com)
- Gastroesophageal reflux disease , or GERD , is when your lower esophageal sphincter doesn't close properly, meaning that often times, contents from your stomach can go back up into your esophagus. (rheumatology-now.com)
- Antacids act locally to buffer gastric and esophageal contents, providing rapid but relatively short-term symptom relief and in only approximately 25% of GERD patients. (aapharmacy.com.my)
- Gastro-Esophageal Reflux Disorder (GERD) or acid reflux is a condition in which the contents of the stomach reflux back into the esophagus (food pipe). (askdrshah.com)
- Transoral fundoplication has been repeatedly shown to be effective in selected patients suffering from gastro-oesophageal reflux disease (GERD) refractory to conservative treatment. (gerdhelp.com)
- WEDNESDAY, Sept. 20, 2023 (HealthDay News) -- Patients with nonerosive gastroesophageal reflux disease (GERD) do not have an increased risk for esophageal adenocarcinoma compared with the general population, according to a study published online Sept. 13 in The BMJ . (msdmanuals.com)
- Dag Holmberg, M.D., Ph.D., from Karolinska Institutet in Stockholm, and colleagues conducted a population-based cohort study to examine the incidence rate of esophageal adenocarcinoma among patients with nonerosive GERD versus the general population. (msdmanuals.com)
- The researchers found that during 2,081,051 person-years of follow-up, 228 of the patients with nonerosive GERD developed esophageal adenocarcinomas (incidence rate, 11.0/100,000 person-years). (msdmanuals.com)
Barrett's8
- The following are additional diseases and conditions that affect the esophagus: Achalasia Acute esophageal necrosis Barrett's esophagus Boerhaave syndrome Caustic injury to the esophagus Chagas disease Diffuse esophageal spasm Esophageal atresia and tracheoesophageal fistula Esophageal cancer Esophageal dysphagia Esophageal varices Esophageal web Esophagitis GERD Hiatus hernia Killian-Jamieson diverticulum Mallory-Weiss syndrome Neurogenic dysphagia Nutcracker esophagus Schatzki's ring Zenker's diverticulum "Esophagus Disorders SECTION II: FGIDs: DIAGNOSTIC GROUPS" (PDF). (wikipedia.org)
- Do not routinely offer endoscopy to diagnose Barrett's oesophagus, but consider it if the person has gastro-oesophageal reflux disease (GORD). (nice.org.uk)
- Patients with Barrett's oesophagus appear to have particularly severe oesophageal motor dysfunction and consequently more severe acid reflux. (bl.uk)
- 11 Of those with Barrett's oesophagus, approximately 0.12%-0.38% per year will progress to oesophageal adenocarcinoma. (bmj.com)
- Since we have effective treatment for Barrett's oesophagus, why then does the incidence of oesophageal cancer continue to rise in the USA? (bmj.com)
- Untreated Barrett's esophagus can lead to esophageal cancer. (aapharmacy.com.my)
- The gradual progression from premalignant Barrett's esophagus to esophageal adenocarcinoma (EAC) provides an ideal model to study the ordering of somatic mutations. (ox.ac.uk)
- Male Barrett's cases (134) were compared to 268 male age-matched controls in each of two control groups (erosive gastro-esophageal reflux and dyspepsia without significant upper gastrointestinal disease). (who.int)
Manometry13
- Manometry helps surgical planning by determining the lower esophageal sphincter (LES) pressure and identifying any esophageal motility disorders. (medscape.com)
- Esophageal manometry defines the function of the LES and the esophageal body (peristalsis). (medscape.com)
- Esophageal manometry is essential for correctly positioning the probe for the 24-hour pH monitoring. (medscape.com)
- The prevalence of oesophageal motor dysfunction in reflux oesophagitis is investigated and compared with healthy controls using oesophageal scintigraphy, manometry, acid clearance test and 24 hour oesophageal pH monitoring. (bl.uk)
- Esophageal manometry (also called esophageal motility study) is a test we use for the diagnosis of motility disorders of the esophagus. (honorhealth.com)
- Manometry is an excellent tool, but some patients may have difficulty with this procedure, so we also offer a sedated esophageal motility assessment alternative. (honorhealth.com)
- It also features a detailed review of esophageal testing including commonly employed methods such as endoscopy, barium testing, manometry, and pH monitoring, as well as newer modalities such as endocopic ultrasoundm impedance and Braco pH testing. (youbeli.com)
- Oesophageal manometry is often used in severe cases to exclude any evidence of concurrent oesophageal dysmotility . (teachmesurgery.com)
- What is esophageal testing, also called manometry, and why is it performed? (houstontxgi.com)
- Esophageal testing or manometry measures the pressures and the pattern of muscle contractions in your esophagus. (houstontxgi.com)
- Esophageal manometry is the test used to diagnose the conditions that can cause these symptoms. (houstontxgi.com)
- What are the possible risks associated with esophageal manometry? (houstontxgi.com)
- If the manometry test cannot find any problems with the oesophageal sphincter muscles, another test called the 24-hour pH monitoring can be used. (whelehans.ie)
Esophagus8
- Esophagogastroduodenoscopy (EGD) demonstrates the anatomy and identifies the possible presence and severity of complications of reflux disease (esophagitis, Barrett esophagus, strictures). (medscape.com)
- Diseases and disorders affecting the esophagus can range from common, treatable conditions like heartburn to more serious issues such as esophageal cancer. (nyp.org)
- Many esophageal disorders can be diagnosed and treated through endoscopy - the insertion of a flexible tube into the esophagus with a camera at its tip. (nyp.org)
- Sometimes, the esophagus muscle and opening become weak, resulting in esophageal disease. (honorhealth.com)
- This atlas provides clinically relevant information on the anatomy, physiology, and disease of the esophagus. (youbeli.com)
- Diseases of the Esophagus , 1 (2), 87-102. (uaeu.ac.ae)
- Esophageal pain, heartburn, and/or difficulty swallowing are often caused by abnormalities in the contractions of the esophageal muscle or abnormalities in the sphincter at the lower end of the esophagus. (houstontxgi.com)
- Together, this suggests the esophagus is exposed to aldehyde stress, and that glandular esophageal cells may be vulnerable to this stress. (nature.com)
Endoscopy7
- Use of 24-hour pH testing helps confirm the diagnosis in patients in whom the history is not clear, atypical symptoms dominate the clinical picture, or endoscopy shows no complications of reflux disease. (medscape.com)
- Our esophageal cancer care teams include specialists from surgery, medical and radiation oncology, and interventional endoscopy who have many years of experience and provide treatments based on the latest scientific studies. (nyp.org)
- B: There was no significant difference between esophageal capsule endoscopy and esophagogastroduodenoscopy (EGD) ( P = 0.64) for combined esophageal and gastroesophageal junction findings on 2-tailed Fischer exact test ( P = 0.66). (wjgnet.com)
- Unfortunately, esophageal disease isn't always seen on an upper endoscopy alone. (honorhealth.com)
- Among those with erosive esophagitis at endoscopy, there were 542 esophageal adenocarcinomas during 1,750,249 person-years (incidence rate, 31.0/100,000 person-years), with an increased overall standardized incidence ratio of 2.36, which became more pronounced with longer follow-up. (msdmanuals.com)
- Upper gastrointestinal endoscopy and double contrast barium radiology were compared prospectively in 45 Ugandan patients with AIDS and upper gastrointestinal oesophageal symptoms. (bvsalud.org)
- Radiology was normal in 2 cases later proved to have definite pathology on endoscopy and histopathologic examination (oesophageal candidiasis). (bvsalud.org)
GORD7
- Gastro-oesophageal reflux disease (GORD) has been linked to a number of extra-esophageal symptoms and disorders, primarily in the respiratory tract. (bmj.com)
- Gastro-oesophageal Reflux (GOR) and Gastro-oesophageal Reflux Disease (GORD) are different. (livingwithreflux.org)
- By definition, GOR is normal, whereas GORD is a disease. (livingwithreflux.org)
- OBJECTIVE: To determine the relative benefits and risks of laparoscopic fundoplication surgery as an alternative to long term drug treatment for chronic gastro-oesophageal reflux disease (GORD). (uea.ac.uk)
- Gastro-oesophageal reflux disease (GORD) is a condition whereby gastric contents from the stomach leaks up into the oesophagus . (teachmesurgery.com)
- Continued and prolonged damage to the oesophageal lining by GORD, if left untreated, can lead to ulcers forming within the tube. (whelehans.ie)
- This condition relates to a change, caused by persistent GORD, in those cells which line the oesophageal tube. (whelehans.ie)
Adenocarcinoma5
- 2-5 The two most prevalent types of oesophageal carcinoma are squamous cell and adenocarcinoma. (bmj.com)
- Squamous cell carcinoma used to be the most prevalent oesophageal cancer in the Western world, but it has been surpassed by oesophageal adenocarcinoma in the last 40 years. (bmj.com)
- Oesophageal adenocarcinoma is an extremely lethal form of cancer with a five-year survival rate of 15%-20% despite best available therapy. (bmj.com)
- Volatile aldehydes are enriched in esophageal adenocarcinoma (EAC) patients' breath and could improve early diagnosis, however the mechanisms of their production are unknown. (nature.com)
- BACKGROUND: Use of statins has been associated with a reduced incidence of esophageal adenocarcinoma in population-based studies. (who.int)
Disorders11
- At NewYork-Presbyterian, we unite the extraordinary expertise of gastroenterologists, surgeons, and interventional endoscopists to diagnose and treat all types of esophageal disorders, using therapies based on the latest advances. (nyp.org)
- The diagnosis of esophageal disorders requires specialized testing, equipment, technicians, and doctors to interpret the findings and determine the cause of your symptoms. (nyp.org)
- Our esophageal care specialists include gastroenterologists, surgeons, radiologists, allergists, nurses, speech and swallowing therapists, registered dietitians, integrative health specialists and others with the skills and understanding to provide the highest quality care to people with esophageal disorders. (nyp.org)
- Motility disorders, abnormal esophageal inflammation, non-acid reflux and impaired gastroesophageal relaxation all require advanced diagnostic techniques. (honorhealth.com)
- Adolescents and young patients may develop conditions such as eosinophilic esophagitis while middle-age and older patients may develop esophageal strictures, rings and motility disorders such as achalasia. (honorhealth.com)
- This technology gives us dedicated information regarding the mechanical properties of the esophageal wall and opening dynamics of the esophagogastric junction that objectively helps evaluate esophageal motility disorders, eosinophilic esophagitis and esophageal strictures. (honorhealth.com)
- Esophageal diseases are among the most commonly seen disorders in the practice of internists, gastroenterologists, and surgeons around the world. (youbeli.com)
- Both the diagnosis and treatment of common and uncommon manifestations of esophageal disorders are covered in-depth, with each disorder illustrated by representative images-in full color-supported by succinct explanatory text. (youbeli.com)
- Nursing Central , nursing.unboundmedicine.com/nursingcentral/view/Diseases-and-Disorders/73586/all/Esophageal_Diverticula. (unboundmedicine.com)
- This review which is directed primarily to endoscopists in training briefly evaluates the role of esophagoscopy in the diagnosis and therapy of benign esophageal disorders. (uaeu.ac.ae)
- Background Primary eosinophilic gastrointestinal diseases (EGID) are chronic inflammatory disorders of the gastrointestinal tract with unknown etiology . (bvsalud.org)
Gastric3
- Gastro-oesophageal reflux disease refers to reflux of gastric contents into the oesophagus leading to oesophagitis, reflux symptoms sufficient to impair quality of life, or long-term complications. (nih.gov)
- Figure 2 Inter-observer agreement between esophageal and gastric findings and results of esophageal findings on capsule vs esophagogastroduodenoscopy. (wjgnet.com)
- The repeated refluxed acidic gastric contents (or rarely alkaline bile) result in inflammation to the oesophageal mucosa . (teachmesurgery.com)
Sphincter4
- Transient relaxation of the lower oesophageal sphincter is believed to be the primary mechanism of the disease although the underlying cause remains uncertain. (nih.gov)
- The discriminatory value of the test was slightly better if the probe was at 5 cm above the lower oesophageal sphincter than at 10 cm above the LOS. (bl.uk)
- The lower oesophageal sphincter controls the passage of contents from the oesophagus to the stomach. (teachmesurgery.com)
- The presence of a hiatus hernia can increase these reflux episodes, due to disruption to the oesophageal sphincter. (teachmesurgery.com)
Squamous2
- For esophageal squamous cancers, inactivating variants in ALDH2 convey predisposing risk 10 . (nature.com)
- How do you manage upper esophageal squamous cell in situ disease that is not amenable to endoscopic mucosal resection? (themednet.org)
Eosinophilic esophagitis2
- Endoscopic photograph of concentric esophageal rings, also known as "trachealization", in a 14 yo with Eosinophilic Esophagitis. (naspghan.org)
- Endoscopic photograph of linear esophageal corrugated, furrows in an 11 yo with Eosinophilic Esophagitis. (naspghan.org)
Oesophagitis6
- Discuss the person's preferences and their individual risk factors (for example, long duration of symptoms, increased frequency of symptoms, previous oesophagitis, previous hiatus hernia, oesophageal stricture or oesophageal ulcers, or male gender). (nice.org.uk)
- A high prevalence of oesophageal motor dysfunction in patients with oesophagitis has been found. (bl.uk)
- The effect of endoscopically confirmed complete healing of oesophagitis on oesophageal motor function has been examined. (bl.uk)
- The results from these studies suggest that oesophageal motor dysfunction in reflux oesophagitis (and probable gastro-oesophageal reflux disease in general) is a primary phenomenon and not a consequence of inflammation. (bl.uk)
- In patients with asthma, the average prevalence of abnormal oesophageal pH, oesophagitis and hiatal hernia was 50.9%, 37.3% and 51.2%, respectively. (bmj.com)
- Gastro-oesophageal reflux disease: short and long term treatment of severe erosive oesophagitis associated with gastro-oesophageal reflux disease, as well as management of acid-related dyspepsia (symptomatic gastro-oesophageal reflux disease). (medicinep.com)
Heartburn3
- What Causes Heartburn or Gastroesophageal Reflux Disease? (rheumatology-now.com)
- discusses gastroesophageal reflux disease and heartburn. (rheumatology-now.com)
- Family Physician discusses gastroesophageal reflux disease and heartburn. (rheumatology-now.com)
Stomach1
- With oesophageal cases, this tool checks the surface of the oesophagus for damage by stomach acid. (whelehans.ie)
Atresia1
- Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) is the most common congenital malformation of the upper digestive tract. (lu.se)
Varices8
- Scarring ( cirrhosis ) of the liver is the most common cause of esophageal varices. (medlineplus.gov)
- Any type of long-term (chronic) liver disease can cause esophageal varices. (medlineplus.gov)
- People with chronic liver disease and esophageal varices may have no symptoms. (medlineplus.gov)
- This test screens for esophageal varices and treats them before there is bleeding. (medlineplus.gov)
- Portacaval shunts or surgery to reduce the pressure in the esophageal varices are treatment options, but these procedures are risky. (medlineplus.gov)
- People with bleeding varices from liver disease may need more treatment for their liver disease, including a liver transplant. (medlineplus.gov)
- Bleeding esophageal varices are a serious complication of liver disease and have a poor outcome. (medlineplus.gov)
- Introduction: La ligature des varices Å sophagiennes constitue un des piliers de la prise en charge de l'hémorragie digestive par rupture des varices Å sophagiennes. (bvsalud.org)
Dysphagia1
- Endoscopic photograph of an esophageal web in a 6 yo who presented with dysphagia and a food impaction. (naspghan.org)
Patients15
- Some evidence suggests that once patients develop the disease, severity is determined early and patients seem to continue with that phenotype long term. (nih.gov)
- Most patients need long-term treatment because the disease usually relapses. (nih.gov)
- Currently, no role exists for CT, MRI, or ultrasonography in the routine evaluation of patients with reflux disease. (medscape.com)
- A study by Fogh et al of induction chemoradiotherapy followed by surgery, a strategy that is widely used in treating esophageal cancer, found that perioperative morbidity and mortality with this approach was not significantly different in patients aged 70 years or older compared with younger patients. (medscape.com)
- The effect of a long period of remission on oesophageal acid exposure has been examined in a subset of patients and again found not to affect the magnitude of acid exposure on cessation of antisecretory medication. (bl.uk)
- The aim of this study was to evaluate the relationship between the monocyte count assessed at diagnosis and disease-free survival and prognosis in patients with esophageal cancer. (researchsquare.com)
- The retrospective study included 145 patients with esophageal cancer who presented to Van Training and Research Hospital Medical Oncology outpatient clinic between January 2015 and September 2020. (researchsquare.com)
- Disease-free survival was 17.3 months (95% CI: 8.4-26.2) in patients with a monocyte count ≥515/μL as opposed to 38.5 months (95% CI: 28. (researchsquare.com)
- Our findings showed that monocyte count is a prognostic factor affecting disease-free survival in patients with esophageal cancer, regardless of histological subtype. (researchsquare.com)
- In the present study, we aimed to investigate whether the monocyte count measured at the time of diagnosis can be used as a new prognostic biomarker in predicting disease-free survival in patients with esophageal cancer. (researchsquare.com)
- Esophageal conditions can affect patients of all ages. (honorhealth.com)
- It can quantify the burden of reflux disease and is especially important for patients in whom medical treatment has failed and surgery is considered . (teachmesurgery.com)
- The patients with difficult diseases posed the challenge and encouraged Dr. Shah to pursue research in different areas of homeopathy to find better solutions. (askdrshah.com)
- The Doctor of the future will no longer treat the human frame with drugs but rather will cure and prevent disease with Nutrition - Thomas Edison The Department of Nutrition and Dietetics at The Madras Medical Mission is committed to perform Nutritional Assessment, design and implement appropriate Medical Nutrition Therapy for all patients who are obtaining the treatment from this institution portal. (org.in)
- This study aimed to characterize the common chronic respiratory diseases, along with their lung function and possible determinants in symptomatic patients attending clinics at Bishoftu General Hospital, Ethiopia. (who.int)
Mucosa1
- Our study suggests that these repeated gastroscopies are probably unnecessary for people with reflux disease who have a normal esophageal mucosa," Holmberg said in a statement. (msdmanuals.com)
Complications1
- MAIN OUTCOME MEASURES: The disease specific REFLUX quality of life score (primary outcome), SF-36, EQ-5D, and medication use, measured at time points equivalent to three and 12 months after surgery, and surgical complications. (uea.ac.uk)
Cancer8
- Esophageal cancer is a cancer with a high mortality rate, ranking sixth in cancer-related deaths in the world. (researchsquare.com)
- Significant parameters used in the determination of the prognosis and survival of esophageal cancer include tumor stage, surgical margin, and metastatic lymph node status. (researchsquare.com)
- Due to the high mortality rate of esophageal cancer, exploration of new prognostic biomarkers for this tumor is of paramount importance. (researchsquare.com)
- Signs and symptoms of lung cancer occur when the disease gets advanced. (hashmiclinic.com)
- A study by Fogh et al examined the use of induction chemoradiotherapy followed by surgery a strategy that is widely used in treating esophageal cancer. (medscape.com)
- Whilst the condition does not normally present any symptoms other than reflux, there is a small risk that affected cells may turn cancerous triggering the onset of oesophageal cancer. (whelehans.ie)
- An analysis of bacteria present in the mouth showed that some types of bacteria that lead to periodontal disease were associated with higher risk of esophageal cancer, explains Jiyoung Ahn, PhD, an associate professor and associate director for population science at the Laura and Isaac Perlmutter Center at NYU Langone Health in New York in Cancer Research, a journal of the American Association for Cancer Research. (afcr.org)
- Esophageal cancer is the eighth most common cancer and the sixth leading cause of cancer death worldwide, Ahn said. (afcr.org)
Surgical1
- It also provides accurate esophageal characterization, which can assist with targeted surgery and assessment of post-surgical states. (honorhealth.com)
Erosive1
- In non-erosive reflux disease, acid suppression is better than placebo but the response rate is lower. (nih.gov)
Centers for Diseas4
- Centers for Disease Control and Prevention. (cdc.gov)
- The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. (cdc.gov)
- The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
- Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
Diagnostic2
- The usefulness of 24 hour pH monitoring as a diagnostic tool for this disease is examined with particular regard to the importance of the position of the pH electrode in the oesophagus. (bl.uk)
- In conclusion, mutations in EAC driver genes generally occur exceptionally early in disease development with profound implications for diagnostic and therapeutic strategies. (ox.ac.uk)
Shortness of bre1
- Early on, these symptoms may be noticeable only when exercising, but as the disease progresses, you could experience shortness of breath with minimal or no activity. (ctsurgerypatients.org)
Peptic ulcer1
- Offer H pylori eradication therapy to people who have tested positive for H pylori and who have peptic ulcer disease. (nice.org.uk)
Surgery2
- Minimally invasive esophageal surgery. (nyp.org)
- Currently, NO MEDICATION can cure aortic valve disease, so it is most commonly treated with surgery. (ctsurgerypatients.org)
Endoscopic1
- Endoscopic photograph of an inflammatory poly in a 15 yo with chronic gastroesophageal reflux disease. (naspghan.org)
Strictures1
- Conversely, single-contrast techniques are more sensitive for structural defects such as hiatal hernias and strictures or esophageal rings. (medscape.com)
Morbidity and morta1
- Although they are leading causes of morbidity and mortality globally, chronic respiratory diseases have received relatively little public attention. (who.int)
Diagnosis and management1
- Updated guidelines from the American College of Gastroenterology (ACG) on the diagnosis and management of gastroespohageal reflux disease in adults. (pennutrition.com)
Ambulatory1
- Ambulatory oesophageal pH monitoring also seems to be insensitive despite high specificity. (nih.gov)
Inflammatory3
- Esophageal inflammatory and neoplastic diseases are better detected with double-contrast techniques. (medscape.com)
- If female is having problem with irregular periods, endometriosis, pelvic inflammatory disease, over 35 age , painful periods or painful coition or falling the semen out of vagina should get the treatment. (hashmiclinic.com)
- Ulcerative colitis (UC) is a chronic inflammatory disease that compromises the colon, affecting the quality of life of individuals of any age. (bvsalud.org)
Pathophysiology1
- The literature on the pathophysiology of this disease is reviewed. (bl.uk)
Lung2
Symptom1
- The main symptom of gastro-oesophageal reflux disease is chest pain . (teachmesurgery.com)
Cancers1
- Stage I, II, and III esophageal cancers are all potentially resectable. (medscape.com)