Fetal Diseases

Persistent fetal circulation

Fetal alcohol spectrum disorder

Fetal circulation

Fifth disease

Fetal viability

Perinatal mortality

Environmental toxicants and fetal development

Vanishing twin

Mycoplasmataceae

Hemolytic disease of the newborn

Pediatrics

Hypoxia (medical)

Thrombocytopenia

Christian Kielland

Infant formula

Hemolytic disease of the newborn (anti-RhE)

Miscarriage

Iopydol

Prontosil

Thalidomide

Neurodevelopmental disorder

Cardiovascular disease in women

Bioelectricity

Rh disease

Etamsylate

Aspermia

Caesarean section

Vein of Galen aneurysmal malformations

Glossary of breathing apparatus terminology

Bubble CPAP

Outcomes11

• Clinicians should be made aware of possible adverse fetal outcomes in pregnant women infected with Tonate virus. (cdc.gov)
• HPD is a risk factor independent of lupus disease activity, and it is strongly associated with poor fetal outcomes, particularly stillbirth, prematurity and need for caesarean section. (lupus.org)
• Overall, more than half (58%) of the pregnancies resulted in poor fetal outcomes. (lupus.org)
• Fewer than half (46.8%) of the women who conceived while their lupus was in remission experienced poor fetal outcomes, and the researchers found that disease activity during conception was associated with a three-fold increased risk of adverse fetal outcomes. (lupus.org)
• The exposure-disease model is often used to conceptualize how toxicant exposure occurs and to identify the steps necessary to cause disease or other adverse health or developmental outcomes. (cdc.gov)
• As well, early postnatal growth trajectories are more associated with adult disease outcomes and there is strong evidence that rapid postnatal growth can amplify the effects of retarded fetal growth. (researchwithrutgers.com)
• There were 13 cases (8.6%) of congenital heart diseases and 17 (11.3%) of valvular heart diseases (1 case of severe pulmonary stenosis) all with good outcomes. (romanianjournalcardiology.ro)
• The study objective is to compare neurodevelopmental (ND) and behavioral outcomes between children with Down syndrome (DS) who had complete atrioventricular septal defect (CAVSD) repair and children from the same clinical sites with DS without major congenital heart disease (CHD) requiring previous or planned CHD surgery. (nih.gov)
• Our findings with PinT and other intracellularly induced [small RNAs] illustrate how small perturbations in the infection process, such as dysregulation of a few Salmonella mRNAs, can propagate through the entire host system, potentially leading to different disease outcomes in the context of a whole organism," the researchers concluded. (genomeweb.com)
• Objective: This retrospective cohort study describes the modulation of disease activity during gestation and in the year following delivery as well as maternal and neonatal outcomes in a monocentric cohort of women with juvenile idiopathic arthritis (JIA).Methods: Disease activity was assessed using DAS28-CRP before conception and every 3 months during pregnancy and in the first year postpartum. (unimi.it)
• Adjusted for breastfeeding and DAS28-CRP score in the third trimester, postconceptional exposure to biologics was inversely related with disease activity in the postpartum: the longer the patient continued treatment, the lower the probability of experiencing an adverse pregnancy outcome.Conclusion: These data offer novel insights on how treatment affects disease activity during pregnancy and postpartum as well as obstetric outcomes in women with JIA. (unimi.it)

Centers for Diseas4

• Centers for Disease Control and Prevention. (cdc.gov)
• The Centers for Disease Control and Prevention (CDC) and the American College of Obstetrics and Gynecology (ACOG) continue to emphasize the importance of vaccinations for pregnant people. (cdc.gov)
• The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
• The Centers for Disease Control and Prevention (CDC) studies show FAS occurring in 0.2 to 1.5 infants for every 1,000 live births in certain areas of the US, with the most recent study finding FAS in 0.3 out of every 1,000 children from 7-9 years old [8] [9] . (aao.org)

Hypoxia and demise2

• [ 1 ] Although initial research showed promise, the fetoplacental response to bypass was characterized by cytokine activation, endothelial dysfunction, and increased resistance in the placenta, with fetal hypoxia and demise as end results. (medscape.com)
• [ 1 ] Although initial research showed promise of reproducibility in technique, the fetoplacental response to bypass, characterized by an end result of fetal hypoxia and demise, deterred complete success. (medscape.com)

Human fetal cardiac1

• The earliest reported human fetal cardiac therapy of any kind took place in 1975 and involved maternal-fetal transplacental administration of a beta blocker in the setting of fetal ventricular tachyarrhythmia. (medscape.com)

Maternal-fetal medicine spec3

• The care of a maternal-fetal medicine specialist can significantly contribute to the baby's health before and after birth. (pediatrix.com)
• Women having a high-risk pregnancy should be seen more frequently for close monitoring by a maternal-fetal medicine specialist, a physician specially trained to treat high-risk pregnancies. (pediatrix.com)
• Dr. Gary Fruhman, MD is a Maternal-Fetal Medicine Specialist in Staten Island, NY. (sharecare.com)

Result of fetal1

• Atherosclerosis and related coronary heart diseases (CHDs) appear to be the result of fetal programming, with the cardiovascular system, and particularly the endothelium component, being the principal target of this process. (unipa.it)

Pregnancy15

• A newly published study finds that women in India with lupus have a low risk of experiencing a major flare (i.e., significant disease activity) during their pregnancy when conception happens during a time of disease stability. (lupus.org)
• Use of the medication hydroxychloroquine (also known as Plaquenil) was also associated with decreased risk of disease flares during pregnancy in women in remission at the time of conception. (lupus.org)
• Since risk of pregnancy complications and lupus flares partly depends on the population studied, these latest findings add important new insights into maternal and fetal health risks among women with lupus around the world. (lupus.org)
• For the best outcome, preplan pregnancy in consultation with you doctor when (your) lupus (disease) is stable and you are on treatment with safe medications. (lupus.org)
• Risk factors in pregnancy and diseases of the fetus and newborn / Richard L. Naeye, Nebiat Tafari. (who.int)
• It is starting to replace the more invasive and riskier tests for detecting fetal abnormalities that are often inaccurate and can only be done during later stages of pregnancy. (genomeweb.com)
• Genomic microarray can detect ROH, which may indicate an increased risk for autosomal recessive (AR) disease for genes contained within the ROH, and/or the risk of an imprinting disorder due to uniparental disomy (UPD), or molar pregnancy. (arupconsult.com)
• Although with increasing incidence, preexistent or newly induced cardiovascular diseases are still underdiagnosed in pregnancy. (romanianjournalcardiology.ro)
• A local prospective registry on cardiovascular diseases in pregnancy. (romanianjournalcardiology.ro)
• A maternal-fetal medicine (MFM) specialist is specially trained to treat women with diabetes during pregnancy. (pediatrix.com)
• Fetal Alcohol Syndrome (FAS) is an irreversible congenital condition that is a result of maternal alcohol use during pregnancy [1] . (aao.org)
• The Belgian research organization imec and Bloomlife , a company that develops pregnancy monitoring technology, has unveiled a new chip capable of tracking five channels of fetal heart rate ECG (electrocardiography) along with mobility of the child inside the womb. (medgadget.com)
• The prototype device, dubbed BeatleIC, is capable of detecting fetal ECG as early as 20 weeks into a pregnancy. (medgadget.com)
• PE not only affects the foetus, generating complications during pregnancy but also predisposes them to chronic diseases in adulthood. (biomedcentral.com)
• However, in the third trimester of pregnancy, which is also when foetal growth is greatest, overall LPL activity decreases, coupled with increased lipolytic and catabolic activity due to insulin resistance that occurs at the time of pregnancy [ 11 ]. (biomedcentral.com)

Prenatal6

• During the 2019 rainy season, a 33-year-old woman living in the Bas Maroni region of French Guiana was referred to the prenatal diagnosis unit at West French Guiana Hospital Center (Saint-Laurent-du-Maroni, French Guiana) for fetal anomalies. (cdc.gov)
• The software is designed to analyze whole-genome sequence data from samples of cell-free DNA (cfDNA) extracted from maternal blood plasma, one of the newer and less invasive forms of prenatal genetic testing that are becoming more commonly used to screen fetuses for heritable genetic diseases and identify abnormalities. (genomeweb.com)
• It is the recommended first-tier test for patients undergoing prenatal diagnosis for the indication of a fetal structural abnormality detected by ultrasound (unless the structural abnormality is strongly suggestive of a specific aneuploidy, in which case, karyotype with or without fluorescence in situ hybridization [FISH] may be offered before genomic microarray). (arupconsult.com)
• Due to high carrier rates and the severity of the disease, population screening and prenatal diagnosis of Tay-Sachs disease are routinely carried out in Israel. (tau.ac.il)
• The assay of hexosaminidase A (Hex A) activity is carried out with synthetic substrates, 4-methylumbelliferyl-6-sulfo-N-acetyl-β- glucosaminide (4-MUGS) and 4-methylumbelliferil-N-acetyl-β-glucosamine (4-MUG), and the DNA-based analysis involves testing for the presence of specific known mutations in the α-subunit gene of Hex A. Prenatal diagnosis of Tay-Sachs disease is accomplished within 24-48∈h from sampling. (tau.ac.il)
• Our board-certified maternal-fetal medicine (MFM) specialists provide prenatal care for expectant patients with complicated or high-risk pregnancies. (pediatrix.com)

Cardiology1

• Royal Brompton has a foetal cardiology centre, which is known worldwide. (rbhcharity.org)

20231

• Hoffman, DJ & Sommer, AD 2023, Early origins of disease: Non-fetal . (researchwithrutgers.com)

Abnormalities3

• In rare cases, however, carrier females have shown some retinal abnormalities or mild hearing loss associated with Norrie disease. (medlineplus.gov)
• For other fetal testing to detect cytogenetic abnormalities, refer to the Laboratory Test Directory . (arupconsult.com)
• Examples of cases with newborns who with sustained fetal circulation are pulmonary hypoplasia and genetic abnormalities. (wikipedia.org)

Physiology4

• Fetal physiology and medicine : the basis of perinatology / edited by Richard W. Beard and Peter W. Nathanielsz. (who.int)
• Given the now substantial body of knowledge regarding the fetal physiology and natural history of these lesions in utero and the success of balloon aortic and pulmonary valvuloplasty in preventing or reversing newly onset ventricular dysfunction postnatally in infants, there is a theoretical rationale for intervention to relieve valvar stenosis or to enlarge a restrictive atrial septal opening in fetal life. (medscape.com)
• The goal of this study is to evaluate the impact of abnormal fetal cerebrovascular physiology with neurodevelopmental delay. (nih.gov)
• In the 1980s, a foetal programming concept emerged that suggested that the intrauterine environment determines and programmes physiology and metabolism throughout life [ 8 ]. (biomedcentral.com)

Pulmonary4

• Fetal pulmonary valvuloplasty (FPV) would not meaningfully change the clinical course for either of these two groups. (medscape.com)
• [ 15 , 16 ] as well as provided evidence that fetal valvuloplasty in conditions of atretic or stenotic valves of the aorta and pulmonary artery can facilitate the chance of biventricular circulation after birth, whereas septoplasty for intact or severely restrictive interatrial septum may improve postnatal stability and chances of survival after initial palliative surgery. (medscape.com)
• Persistent fetal circulation is a condition caused by a failure in the systemic circulation and pulmonary circulation to convert from the antenatal circulation pattern to the "normal" pattern. (wikipedia.org)
• This study is seeking to define and determine the prevalence of pulmonary vascular disease and diastolic dysfunction as assessed by the gold standard of invasive hemodynamic cardiopulmonary exercise testing. (nih.gov)

Neonatal Pathology1

• Fetal and neonatal pathology : perspectives for the general pathologist / edited by A. J. Barson on behalf of the Royal College of Pathologists. (who.int)

Utero9

• Fetal therapy is a broad term that encompasses a range of transplacental medications, catheter-based interventions, fetoscopic procedures, minimally invasive fetoscopic surgical procedures, open fetal surgical procedures, and ex-utero intrapartum treatment (EXIT) procedures. (medscape.com)
• this technology has also enabled the field of congenital heart disease to gain greater understanding of the unique fetal hemodynamics and the mechanisms involved in the evolution of cardiac disease in utero. (medscape.com)
• [ 14 ] They also suggest that successful fetal procedures lead to improvement in functional chamber development and myocardial function while the fetus is still in utero. (medscape.com)
• [ 19 ] However, much effort must be applied to appropriate planning and selection of candidates (maternal and fetal) to minimize the obvious complications and risks associated with in-utero interventions. (medscape.com)
• Decades of research now support the concept that specific chronic diseases of adulthood have origins in utero or during early childhood. (researchwithrutgers.com)
• Placenta assumes a pivotal role in programming the fetal experience in utero due to the adaptive changes in structure and function. (unipr.it)
• In the words of the authors, "it is plausible that in utero telomere biology represents a molecular mechanism whereby stress exposure in this critical period before birth can impact aging and subsequent disease susceptibility over the lifespan. (theprimalmind.com)
• The Maternal Stress Shortens Fetal Telomeres and Programs Aging and Disease In Utero by The Primal Mind , unless otherwise expressly stated, is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 2.5 Canada License . (theprimalmind.com)
• Fetal development is a critical window of exposure-related susceptibility because the etiology of diseases in adulthood may have a fetal origin and may be attributed to adverse effects of in utero environmental exposures. (nature.com)

Cardiac intervention1

• In the years since that landmark paper, however-in large part as a consequence of technical and scientific advances in maternal-fetal medicine, surgical technique, and fetal echocardiography-fetal therapy has also grown to include fetal cardiac intervention (FCI). (medscape.com)

Infectious diseases1

• Our study provides a paradigm for a sensitive RNA-based analysis of intracellular bacterial pathogens and their hosts without physical separation, as well as a new discovery route for hidden functions of pathogen genes," senior author Jörg Vogel, a molecular infection biology and infectious diseases researcher at the University of Würzburg, and colleagues wrote. (genomeweb.com)

Diagnosis4

• Regarding the depression diagnosis, the evaluation of Prime-MD showed that 90% of the women didn't present enough symptoms to characterize the disease. (bvsalud.org)
• The three grant awardees selected this year by a panel of experts and advisors are: Karina Lopes, who aims to improve diagnosis of abnormal aortas in foetuses, Dr Carmel Stock , who wants to better predict the likelihood a patient with Scleroderma will go on to develop interstitial lung disease and Andreia Pinto , who will be researching how Covid-19 infects cells. (rbhcharity.org)
• The Heart Center brings together a select group of specialists to offer extensive expertise in the diagnosis and treatment of infants and children with heart disease. (orlandohealth.com)
• Mesenchymal hamartoma of the liver is a rare benign tumor of children, which definitive diagnosis during the fetal period remains difficult, despite advances in antenatal imaging. (rarejournal.org)

Placenta3

• Fetal hydrops is defined by the demonstration of fluid accumulations in at least two of these four fluid compartments.3 But the placenta and the amniotic sac have sometimes been included as additional "fetal compartments. (taylorfrancis.com)
• Our finding that BC particles accumulate on the fetal side of the placenta suggests that ambient particulates could be transported towards the fetus and represents a potential mechanism explaining the detrimental health effects of pollution from early life onwards. (nature.com)
• Hence, particle translocation to the human placenta following inhalation under real-life conditions is insufficiently studied while being essential in understanding the effects on fetal health 24 . (nature.com)

Deaths1

• on follow up after delivery (120 patients), premature birth, fetal weight, Apgar score and deaths were recorded. (romanianjournalcardiology.ro)

Adulthood2

• Many experimental studies have been conducted to explain the phenotypic consequences of fetal-placental perturbations that predispose to the genesis of metabolic syndrome, obesity, diabetes, hyperinsulinemia, hypertension, and cardiovascular disease in adulthood. (unipr.it)
• The objective of the review was to analyse the information the current information about exists about the impact generated by the oxidation of LDL and HDL lipoproteins in neonates of women with preeclampsia and how these alterations can predispose the neonate to develop diseases in adulthood. (biomedcentral.com)

Prevention1

• Promote health improvement, wellness, and disease prevention in cooperation with patients, communities, at-risk populations, and other members of an interprofessional team of healthcare providers. (cdc.gov)

Mortality5

• However, among the 10 leading causes of death in the United States, New Mexico has mortality rates that are lower than the U.S. rates for the following causes: heart disease, cancer, stroke, Alzheimer's disease, influenza/pneumonia and kidney disease. (cdc.gov)
• However, among the 10 leading causes of death in the United States, the silver state has mortality rates that are lower than the U.S. rates for the following causes: cancer, stroke, Alzheimer's Disease and diabetes. (cdc.gov)
• The International Statistical Classification of Disease and Related Health Problems (commonly referred to as the International Classification of Diseases, ICD) is the global standard classification for mortality and morbidity statistics. (who.int)
• Extensive preparation was devoted to a review of the suitability of the structure of ICD, which was by definition a statistical classification of diseases and other health problems, to serve a wide variety of needs for mortality statistics, morbidity statistics, reimbursement, measuring quality of care, patients' safety, monitoring primary care and clinical recording. (who.int)
• for example, it is closely associated with fetal and neonatal mortality and morbidity, inhibited growth and cognitive development, and noncommunicable diseases ( NCD s) later in life. (who.int)

Surgery3

• Experimental animal models of open fetal cardiac surgery began in the 1980s, with the aim of describing the physiologic and pathologic impacts of extracorporeal circulatory bypass. (medscape.com)
• Experimental studies on open fetal cardiac surgery began in the 1980s in animal models to study the physiologic and pathologicl mechanisms of extracorporeal circulatory bypass. (medscape.com)
• City University London covers a download fetal and hybrid procedures in congenital heart diseases same of significant ambient meaning from a surgery learning useful ', with molecular foods leading overcome. (isak-rubenchik.de)

Fetus2

• Reproductive-rights opponents point to premature neonates as evidence of pain in a fetus, but the RCOG analysis found good evidence that conditions within the womb distinguish fetal experience of sensation from those of premature infants of similar gestational age. (medscape.com)
• The fetal cardiovascular system is susceptible to these factors, and developmental programming events cause endothelial dysfunction, small coronary arteries, stiffer vascular tree, fewer cardiomyocytes, coagulopathies and atherogenic blood lipid profiles in the fetus. (unipa.it)

Demise1

• Large hepatic mesenchymal hamartoma leading to mid-trimester fetal demise. (rarejournal.org)

Etiology1

• Persistent fetal circulation in neonates can be reversible or irreversible depending on the classified etiology listed above. (wikipedia.org)

Echocardiography1

• Incremental Detection of Severe Congenital Heart Disease by Fetal Echocardiography Following a Normal Second Trimester Ultrasound Scan in Québec, Canada. (bvsalud.org)

Diabetes4

• Low birthweight is associated with insulin resistance, hypertension, coronary-artery disease, and non-insulin-dependent diabetes (NIDDM). (nih.gov)
• Dermatoglyphics, fetal growth, and insulin dependent diabetes in children under 5 years. (bmj.com)
• If maternal diabetes is longstanding or associated with known microvascular disease, obtain a baseline maternal electrocardiogram (ECG) and echocardiogram. (medscape.com)
• In the long term, overweight and obesity in children increase the risk of health problems later in life, including obesity, diabetes, heart disease, some cancers, respiratory disease, mental health and reproductive disorders. (who.int)

Adult diseases3

• 10% of all births) is a large problem in Western society, and studies have shown that these individuals have an increased risk of developing a number of adult diseases. (edu.au)
• 2020;23:w02113 Balistreri Carmela R. Affiliationskeyboard_arrow_down Summary The theory of David Barker on "the fetal origin of adult diseases" is revolutionising the pathophysiology and aetiopathogenesis of adult human diseases such as atherosclerosis. (unipa.it)
• Paradoxically, pediatricians must feel involved in fighting this condition because of the latest evidences of developmental origins of adult diseases. (unipr.it)

19951

• Since 1995, Maternal-Fetal Medicine of Texas has provided high quality, specialized care to pregnant women by educating, counseling and managing complicated pregnancies to maximize maternal and fetal health. (pediatrix.com)

Genome2

• A sophisticated interplay of exogenous-gestational environmental factors with the fetal genome induces epigenetic changes (microRNA, DNA methylation patterns and histone structure alterations) and expression of altered phenotypes of developing systems. (unipa.it)
• The Toronto method requires whole-genome sequences from the mother and the father in addition to the fetal genome sequence extracted from the cfDNA. (genomeweb.com)

Copy number v1

• NEW YORK (GenomeWeb) - Researchers from the University of Toronto's computer science department and the genomics arm of Canada's Hospital for Sick Children have developed freely available open-source software that offers more statistically sensitive tools for identifying small de novo copy number variants in fetal DNA. (genomeweb.com)

Disorders1

• The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)

Coronary heart d5

• The fetal origins hypothesis states that fetal undernutrition in middle to late gestation, which leads to disproportionate fetal growth, programmes later coronary heart disease. (bmj.com)
• Studies in humans have shown that men and women whose birth weights were at the lower end of the normal range, who were thin or short at birth, or who were small in relation to placental size have increased rates of coronary heart disease. (bmj.com)
• The programming of blood pressure, insulin responses to glucose, cholesterol metabolism, blood coagulation, and hormonal settings are all areas of active research.The BMJ's recent editorial on the fetal origins hypothesis stated that it rests only on the "very general" proposition that fetal undernutrition causes coronary heart disease. (bmj.com)
• The hypothesis states that coronary heart disease is associated with specific patterns of disproportionate fetal growth that result from fetal undernutrition in middle to late gestation. (bmj.com)
• The early epidemiological studies that pointed to the possible importance of programming in coronary heart disease were based on the simple strategy of examining men and women in middle and late life whose body measurements at birth were recorded. (bmj.com)

Gestation5

• Fetal aortic stenosis at 20 weeks' gestation. (medscape.com)
• Even though this measure is not yet law-and hopefully will not become law-it is already planting seeds of confusion about fetal development during gestation, one of the most unfounded being the false existence of fetal pain in the second trimester. (medscape.com)
• This landmark review incontrovertibly found no existence of fetal pain until much later in gestation. (medscape.com)
• Changes in disease activity during gestation and in the first year postpartum were assessed in a linear mixed model for repeated measures.Results: Thirty-one women (49 pregnancies) with persisting JIA and at least one conception were enrolled. (unimi.it)
• Preconceptional DAS28-CRP and number of biological drugs predicted disease activity fluctuation during gestation. (unimi.it)

20192

• The age-adjusted death rate for Alzheimer disease increased from 128.8 per 100,000 in 1999 to 233.8 in 2019. (cdc.gov)
• 2019 ( https://www.who.int/nutrition/publications/UNICEF-WHOlowbirthweight-estimates-2019/en/ ). (who.int)

Intervention4

• Intervention for cardiac defects fits into existing fetal care structures and is an extension of services and clinical research protocols related to fetal treatment. (medscape.com)
• Owing to the complications of any intrauterine intervention, investing in innovative fetal treatment can be considered a useful exercise only when it is made feasible in terms of procedural ease and risks. (medscape.com)
• Furthermore, local oversight should dictate whether, on procedure-based grounds, the proposed fetal intervention constitutes human subjects research, innovative therapy, or clinical care,as well as ensure that the appropriate counseling and consent procedures are followed. (medscape.com)
• The purpose of this study is to evaluate the feasibility and preliminary efficacy of the Promoting Resilience in Stress Management (PRISM) intervention in patients with adult congenital heart disease. (nih.gov)

Heart9

• Objective: To evaluate the presence or not of depression, the existent of maternal-fetal bond and to verify if the maternal-fetal bond can be a risk factor for depression in pregnant women with heart disease. (bvsalud.org)
• Method: We interviewed 20 pregnant women with heart disease, being 10 of clinic and 10 hospitalized in the nursery of the Obstetric Clinic Division - HCFMUSP, through the application of semi-driven interview and Prime-MD. Results: 75% of the patients interviewed reported positive aspects in relation to the feelings associated to the moment that the baby moves, what probably demonstrates a good mother-baby bond. (bvsalud.org)
• Conclusion: Depression was not diagnosed among the pregnant woman with heart disease, what possibly links to a good mother-baby bond's development. (bvsalud.org)
• One of them said that she was really happy that she agreed to have a foetal heart scan done, as it meant she knew that her baby had an abnormal aorta. (rbhcharity.org)
• The benefit of fetal echocardiograms (FE) to detect severe congenital heart diseases (SCHD) in the setting of a normal second-trimester ultrasound is unclear. (bvsalud.org)
• The download fetal and hybrid procedures in congenital heart diseases of each context is to see the project for complex world, accommodate medicine for pathogen and diffusion etc. (isak-rubenchik.de)
• A gradient of 10% or more in oxygenation saturation between simultaneous preductal and postductal arterial blood gas values in absence of structural heart disease documents persistent fetal circulation. (wikipedia.org)
• This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry. (nih.gov)
• In addition, they note that diets containing omega-3s from fish could lower heart disease rates. (medicalnewstoday.com)

Ascites2

• The purpose of this report is to describe what we believe to be the first case of fetal ascites, secondary to generalized cytomegalovirus infection proved by culture. (jamanetwork.com)
• Some series of nonimmune hydrops also include cases of isolated pleural effusion, abdominal ascites, or generalized skin edema, because fluid accumulation in one site may represent an early stage of a disease that may lead to fluid accumulation in several sites at a more advanced stage, especially in diseases known to result in generalized hydrops fetalis. (taylorfrancis.com)

Origins2

• Fetal origins of. (bmj.com)
• This causality concept is known as the Developmental Origins of Health and Disease or Barker hypothesis 1 . (nature.com)

Adverse1

• The exposure-disease model depicts the relationship between an environmental contaminant and an adverse health effect. (cdc.gov)

Clinical4

• Clinical disease: physical signs and symptoms resulting from a sufficiently absorbed toxicant dose. (cdc.gov)
• Many factors determine whether a person exposed to a toxic substance develops a clinical disease. (cdc.gov)
• I had been working as a foetal cardiologist in Brazil, but an opportunity arose to join the clinical group in 2020 as a research sonographer and I took it as I wanted to dedicate some time to research and studying. (rbhcharity.org)
• The Center for Digestive Health and Nutrition provides clinical services to infants an children with symptoms of digestive problems and diseases. (orlandohealth.com)

Cardiovascular system1

• This life period is crucial for developmentally programming body systems (such as the cardiovascular system), their ageing and disease. (unipa.it)

Pregnancies4

• Our Maternal-Fetal Medicine Specialists, or "Perinatologists," have the training and expertise to care for these complicated pregnancies. (utmb.edu)
• After completing their Ob/Gyn training, Maternal-Fetal Medicine Specialists undergo three years of extra training to teach them to deal with even the most complex pregnancies. (utmb.edu)
• Although many general obstetrician-gynecologists have experience caring for high-risk pregnancies, there are times when consultation with, or turning the care over to, one of our Maternal-Fetal Medicine Specialists can make all the difference for a mother, baby, or both! (utmb.edu)
• Maternal-fetal medicine specialists are available to provide additional monitoring and comprehensive care to women with high-risk pregnancies who are hospitalized prior to delivery. (pediatrix.com)

FASD2

• PAE can result in fetal alcohol spectrum disorder (FASD). (aap.org)
• FAS is a syndrome that falls under a larger group of conditions known as Fetal Alcohol Spectrum Disorder (FASD). (aao.org)

Persistent3

• The failure of the circulatory system of the newborn to adapt to these changes by lowering PVR leads to persistent fetal circulation. (wikipedia.org)
• Since this may be a sign of other conditions, persistent fetal circulation must also be characterized by enlargement of right and left ventricles often confirmed through a definitive ECG. (wikipedia.org)
• Persistent fetal vasculature. (aao.org)

Womb1

• In other words, womb stress causes senescence of fetal and placental tissues which can trigger preterm birth. (theprimalmind.com)

Developmental2

• About 30 percent of individuals with Norrie disease develop progressive hearing loss, and 30 to 50 percent of people affected experience developmental delays in motor skills such as sitting up and walking. (medlineplus.gov)
• PE can cause foetal loss, intrauterine growth restriction, or developmental complications. (biomedcentral.com)

Childhood4

• Abnormal vascular development during fetal life and early childhood, as a result of genetic insulin resistance, could also explain the increased risk of hypertension and vascular disease. (nih.gov)
• Your Name ) thought you would like to see this page from the Archives of Disease in Childhood web site. (bmj.com)
• There is substantial evidence that nutritional programming of later disease risk begins during infancy and childhood and may be mediated by several different factors, such as feeding regimes (especially breast-feeding versus artificial feeding) and growth trajectories. (researchwithrutgers.com)
• 2024 ) In Archives of disease in childhood. (lu.se)

Neonates1

• Neonates of mothers with PE have a high risk of cardiovascular diseases, stroke, mental retardation, sensory deficiencies and an increased risk of developing metabolic diseases. (biomedcentral.com)

Syndrome1

• Aortopathy, that is diseases of the aorta, seen in several inherited diseases, such as Marfan syndrome, can lead to reshaping and enlargement of the aorta, and an increased risk of an aortic dissection and rupture. (rbhcharity.org)

Genetic1

• The predisposition to NIDDM and vascular disease is likely to be the result of both genetic and fetal environmental factors. (nih.gov)

Health6

• Principles of Pediatric Environmental Health: How Does Toxic Exposure Cause Children's Disease? (cdc.gov)
• This means that a maternal or fetal condition is present that could affect the health or well-being of the mother or the baby. (utmb.edu)
• This puts a huge strain on the fragile health care system that is also grappling with handling other diseases. (who.int)
• In effect, the telomere/telomerase system is one of the major mediators of health and disease throughout the lifespan. (theprimalmind.com)
• The NIH also report that taking supplementary omega-3s can reduce the risk of death from all health conditions and particularly from cardiovascular disease. (medicalnewstoday.com)
• 3. In order to adequately respond to this high burden of disease and in line with the 2030 Agenda for Sustainable Development, WHO has developed a global health sector strategy on STIs, 2016-2021. (who.int)

Antibodies1

• Definition The Greek-Latin term hydrops fetalis is issued for pathologically increased fluid accumulations in fetal soft tissues and serous cavities.1 Immune hydrops fetalis refers to those cases of hydrops that are caused by alloimmune hemolytic anemia in the presence of circulating maternal antibodies against fetal erythrocytes.2 If there is no evidence of blood group incompatibility (isoimmunization), the hydrops is characterized as being nonimmune hydrops fetalis. (taylorfrancis.com)

Abstract1

• abstract = "Tay-Sachs disease is an autosomal recessive storage disease caused by the impaired activity of the lysosomal enzyme hexosaminidase A. In this fatal disease, the sphingolipid GM2 ganglioside accumulates in the neurons. (tau.ac.il)