Fibrocystic Breast Disease
Breast
Adenofibroma
Fibroadenoma
Natural history of fibroadenomas based on the correlation between size and patient age. (1/234)
BACKGROUND: Several recent studies have reported that most fibroadenomas remain static or regress when they are managed conservatively; however, no such studies have evaluated the breast disorder in Japanese women. To understand the natural history of fibroadenomas in Japanese women, we examined the correlation between the sizes of the fibroadenomas and the women's age. METHODS: Fifty-eight consecutive patients (age range, 17-51 years; mean, 33.9 years) with histologically confirmed fibroadenoma were enrolled in this study. The sizes of the excised fibroadenomas were analyzed in relation to the women's ages. RESULTS: The fibroadenomas decreased significantly in size (Y, mm) with patient age (X, years) (P = 0.0012) according the equation Y = -0.340X + 27.0 (95% confidence limits for the slope, -0.139 to -0.540). From this equation, the mean sizes of the fibroadenoma in women aged 20, 30 and 40 years were expected to be 20.2 mm (95% confidence interval, 16.2-24.2 mm), 16.8 mm (95% confidence interval, 10.8-22.8 mm) and 13.4 mm (95% confidence interval, 5.4-21.4 mm), respectively. The mean annual decrease in the size of the fibroadenomas was 0.340 mm. CONCLUSIONS: Our results indicate that in Japanese women fibroadenomas increase in size more frequently in younger than in older women. Moreover, it is speculated that most fibroadenomas might stop growing when they reach an approximate maximum diameter of 20 mm, after which time they might remain static or regress. (+info)Measurement of prostate-specific antigen in detection of benign or malignant breast disease in women. (2/234)
Using a highly sensitive chemiluminescent enzyme immunoassay, we have evaluated the measurement of serum prostate-specific antigen (PSA) as a potential diagnostic test for differentiation between women with breast cancer and those with benign breast disease. In a controlled study consisting of 284 women with well-documented patient files and matched for age and long-term place of residence, serum samples collected from 90 women with histologically confirmed breast cancer, 94 women with benign breast disease and 100 controls were analysed. Serum total PSA levels in benign breast disease and cancer patients are not statistically different from those of healthy controls. Total PSA levels decrease with age in normal controls and breast cancer patients but not in those with benign breast disease. The total PSA concentration decreases after menopause in healthy women, though not in patients with breast cancer or benign breast disease. Total PSA bore no relation to the histological type or grade of the tumour or the disease stage of the breast cancer patients. In benign breast disease, all mastopathy patients had normal total PSA, whereas elevation of the values was observed in 7% of fibroadenoma patients. Our results show that serum total PSA cannot be used to distinguish between healthy women and/or women with breast cancer or benign breast disease. (+info)Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. (3/234)
The generation of vascular stroma is essential for solid tumor growth and involves stimulatory and inhibiting factors as well as stromal components that regulate functions such as cellular adhesion, migration, and gene expression. In an effort to obtain a more integrated understanding of vascular stroma formation in breast carcinoma, we examined expression of the angiogenic factor vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF); the VPF/VEGF receptors flt-1 and KDR; thrombospondin-1, which has been reported to inhibit angiogenesis; and the stromal components collagen type I, total fibronectin, ED-A+ fibronectin, versican, and decorin by mRNA in situ hybridization on frozen sections of 113 blocks of breast tissue from 68 patients including 28 sections of breast tissue without malignancy, 18 with in situ carcinomas, 56 with invasive carcinomas, and 8 with metastatic carcinomas. A characteristic expression profile emerged that was remarkably similar in invasive carcinoma, carcinoma in situ, and metastatic carcinoma, with the following characteristics: strong tumor cell expression of VPF/VEGF; strong endothelial cell expression of VPF/VEGF receptors; strong expression of thrombospondin-1 by stromal cells and occasionally by tumor cells; and strong stromal cell expression of collagen type I, total fibronectin, ED-A+ fibronectin, versican, and decorin. The formation of vascular stroma preceded invasion, raising the possibility that tumor cells invade not into normal breast stroma but rather into a richly vascular stroma that they have induced. Similarly, tumor cells at sites of metastasis appear to induce the vascular stroma in which they grow. We conclude that a distinct pattern of mRNA expression characterizes the generation of vascular stroma in breast cancer and that the formation of vascular stroma may play a role not only in growth of the primary tumor but also in invasion and metastasis. (+info)Enhanced apoptotic response to photodynamic therapy after bcl-2 transfection. (4/234)
Apoptosis is a cellular death process involving the sequential activation of a series of caspases, endonucleases, and other enzymes. The initiation of apoptosis can be inhibited by overexpression of bcl-2 and certain other members of a related family of proteins. We examined the effects of bcl-2 overexpression on the apoptotic response to photodynamic therapy (PDT), using aluminum phthalocyanine as the photosensitizing agent. In this study, we compared the immortalized human breast epithelial cell line MCF10A with a subline (MCF10A/bcl-2) transfected with the human bcl-2 gene. The latter was approximately 2-fold more sensitive to the phototoxic effects of PDT. At a 50 mJ/cm2 light dose, photodamage to MCF-10A/bcl-2 resulted in a greater loss of the mitochondrial membrane potential (delta(psi)m), enhanced release of mitochondrial cytochrome c, a more rapid and greater activation of caspase-3, and a greater apoptotic response. Western blot analysis revealed that the transfected cell line showed overexpression of both bcl-2 and bax, and that PDT caused selective destruction of bcl-2, leaving bax unaffected. The greater apoptotic response by the transfected line is, therefore, attributed to the higher bax:bcl-2 ratio after photodamage. (+info)Human mammary gland and breast carcinoma contain immunoreactive inhibin/activin subunits: evidence for a secretion into cystic fluid. (5/234)
OBJECTIVE: Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. The present study investigated the localization of inhibin and activin subunits in human normal and pathological breast tissues. DESIGN: A cross-sectional study comparing the expression of inhibin/activin subunits alpha, betaA and betaB in surgical specimens from women undergoing reductive mammoplasty (classified, according to the phase of the menstrual cycle, as follicular, luteal, or postmenopausal), and patients submitted to lumpectomy for fibrocystic disease, benign (intraductal papilloma, adenomyoepithelioma, and hamartoma) or malignant breast neoplams (intraductal, intralobular, and invasive carcinoma). METHODS: Immunohistochemistry was used to localize inhibin alpha and activin betaA and betaB subunits in the cytoplasm of epithelial cells of mammary glands. Dimeric activin A, inhibin A and inhibin B were measured by specific two-site enzyme immunoassay in the cystic fluid collected from patients with fibrocystic disease. RESULTS: An intense staining for the alpha inhibin subunit and a mild staining for betaA and betaB subunits were present in samples obtained from normal breast tissue regardless of menstrual cycle phase, and in fibrocystic disease and benign neoplasms. Carcinoma cells stained weakly to moderately for alpha subunit and were negative for betaA and betaB subunits. Fibrocystic disease was associated with absence of betaA subunit expression in normal epithelial cells and intense staining for all subunits in the apocrine cells. Immunoreactive inhibin A, inhibin B, and activin A were also present in cystic fluid, suggesting a local secretion of these proteins. CONCLUSION: These data suggest a local expression and secretion of inhibin and activin in human normal, fibrocystic disease and neoplastic breast tissues. The low expression of these proteins may facilitate abnormal cell proliferation in breast carcinoma. (+info)Teaching family practice residents breast cyst aspiration. (6/234)
OBJECTIVE: To conduct the first study of teaching family practice residents the technique of breast cyst aspiration (BCA) using the Toronto Breast Cyst Aspiration Model (TBCAM) in a workshop. To determine whether this training increases their likelihood of performing the procedure in the future. To discover how residents evaluate the workshop as a teaching method. DESIGN: Prospective parallel-group trial from August to November 1997. Baseline questionnaires were given to both experimental and control groups in August. The experimental group was given a 1.5-hour workshop and a postworkshop questionnaire. Both groups were then given 3-month follow-up questionnaires. SETTING: Family practice residency program at the University of Toronto. PARTICIPANTS: The experimental group consisted of 15 family practice residents from one university-affiliated hospital site. The control group consisted of 54 family practice residents selected from the remaining sites. MAIN OUTCOME MEASURES: Confidence score, likelihood of performing BCA, and effectiveness of the workshop rated on a Likert scale ranging from 1-low to 5-high; and knowledge of BCA rated from 0 to 7. RESULTS: Three months after the workshop, 62% of study subjects and 31% of controls were above the median confidence score of 3.2 (chi 2 3.4, P > .05); 76% of subjects but only 11% of controls were above the median knowledge score of 4 (chi 2 16.67, P < .001); and 75% of subjects and 34% of controls were above the median likelihood to perform score of 3 (chi 2 5.37, P < .05). Most (95%) workshop effectiveness scores were 4s or 5s. CONCLUSIONS: Workshop training resulted in higher confidence, greater knowledge, and more likelihood of performing BCA. The workshop using the TBCAM was evaluated as a highly effective way to teach BCA. (+info)Management of palpable breast lumps. Consensus guideline for family physicians. (7/234)
OBJECTIVE: To describe an approach to managing women who present with palpable breast lumps. QUALITY OF EVIDENCE: Databases were searched from 1990 to 1998 using the search terms breast lumps, breast diseases, and breast cysts. Bibliographies of the articles obtained were searched for further relevant titles. Most evidence on management of breast cysts was obtained from cohort studies. Evidence on family physicians' approach to managing breast lumps is based on a review of the 1998 Canadian consensus guidelines and a review of a 1998 consensus guideline by 12 University of Toronto surgical oncologists (U of T guidelines). MAIN MESSAGE: Family physicians can manage women presenting with breast lumps if they have skill in breast cyst aspiration. Most breast cysts can be cured in minutes, thus avoiding unwarranted anxiety and eliminating unnecessary additional investigations and referrals. Women presenting with solid lesions should be referred to a surgeon. CONCLUSIONS: Breast cyst aspiration is a simple technique family physicians can use to either cure breast lumps or define appropriate cases for referral. (+info)Human glandular kallikrein in breast milk, amniotic fluid, and breast cyst fluid. (8/234)
BACKGROUND: Human glandular kallikrein (hK2) belongs to the serine protease family of enzymes and has high sequence homology with prostate-specific antigen (PSA). The physiological role of hK2 has not as yet been determined, but there is evidence that it can regulate the proteolytic activity of PSA through processing and activating pro-PSA, an inactive precursor. Thus, it is conceivable that these two secreted proteins may coexist in biological fluids. Currently, hK2 is considered an androgen-regulated and prostate-specific protein. Recently, it has been demonstrated that hK2 is expressed in the breast cancer cell line T-47D after stimulation by steroid hormones, and we reported that hK2 can be detected in a subset of breast tumor extracts. These data suggest that hK2 may be expressed in tissues other than the prostate, such as those in which PSA has already been detected. Because hK2 is a secreted protein, it may be present in various biological fluids. METHODS: We analyzed milk samples from lactating women, amniotic fluid from pregnant women, and breast cyst fluid from patients with gross breast cystic disease, using a highly sensitive and specific immunoassay for hK2. RESULTS: hK2 was present in all three biological fluids. We suggest that the female breast may produce hK2 and provide evidence that hK2 may have value as an additional marker for the discrimination between type I and type II breast cysts. CONCLUSIONS: The female breast produces hK2 in addition to PSA. More studies are necessary to establish the role of this kallikrein in nondiseased breast, gross breast cystic disease, and breast cancer. (+info)Fibrocystic breast disease, also known as fibrocystic change or chronic cystic mastitis, is not actually a disease but a condition that affects many women at some point in their lives. It is characterized by the formation of benign (non-cancerous) lumps or cysts in the breasts, often accompanied by breast pain, tenderness, and swelling.
The condition is caused by hormonal fluctuations that affect the breast tissue, making it more prone to developing fibrous tissue and fluid-filled sacs called cysts. Fibrocystic breast changes are usually harmless and do not increase the risk of breast cancer. However, in some cases, they can make it harder to detect early signs of breast cancer through mammography or self-examination.
The symptoms of fibrocystic breast change may vary from woman to woman and can range from mild to severe. They tend to be more noticeable just before a woman's menstrual period and may improve after menopause. Treatment options for fibrocystic breast changes include pain relievers, hormonal medications, and lifestyle modifications such as reducing caffeine intake and wearing a well-supportive bra. In some cases, draining or removing the cysts may be necessary to alleviate symptoms.
Breast diseases refer to a wide range of conditions that affect the breast tissue. These can be broadly categorized into non-cancerous and cancerous conditions.
Non-cancerous breast diseases include:
1. Fibrocystic breast changes: This is a common condition where the breast tissue becomes lumpy, tender, and sometimes painful. It is caused by hormonal changes and is most common in women aged 20 to 50.
2. Mastitis: This is an infection of the breast tissue, usually occurring in breastfeeding women. Symptoms include redness, swelling, warmth, and pain in the affected area.
3. Breast abscess: This is a collection of pus in the breast tissue, often caused by bacterial infection. It can be painful and may require surgical drainage.
4. Fibroadenomas: These are benign tumors made up of glandular and fibrous tissue. They are usually round, firm, and mobile, and can be removed if they cause discomfort.
5. Intraductal papillomas: These are small, wart-like growths that occur in the milk ducts. They may cause nipple discharge, which can be bloody or clear.
Cancerous breast diseases include:
1. Breast cancer: This is a malignant tumor that starts in the breast tissue. It can spread to other parts of the body if left untreated. There are several types of breast cancer, including ductal carcinoma, lobular carcinoma, and inflammatory breast cancer.
2. Paget's disease of the nipple: This is a rare form of breast cancer that affects the skin of the nipple and areola. It can cause symptoms such as redness, itching, burning, and flaking of the nipple skin.
3. Phyllodes tumors: These are rare breast tumors that can be benign or malignant. They usually grow quickly and may require surgical removal.
It is important to note that not all breast lumps are cancerous, and many non-cancerous conditions can cause breast changes. However, any new or unusual breast symptoms should be evaluated by a healthcare professional to rule out serious conditions such as breast cancer.
The breast is the upper ventral region of the human body in females, which contains the mammary gland. The main function of the breast is to provide nutrition to infants through the production and secretion of milk, a process known as lactation. The breast is composed of fibrous connective tissue, adipose (fatty) tissue, and the mammary gland, which is made up of 15-20 lobes that are arranged in a radial pattern. Each lobe contains many smaller lobules, where milk is produced during lactation. The milk is then transported through a network of ducts to the nipple, where it can be expressed by the infant.
In addition to its role in lactation, the breast also has important endocrine and psychological functions. It contains receptors for hormones such as estrogen and progesterone, which play a key role in sexual development and reproduction. The breast is also a source of sexual pleasure and can be an important symbol of femininity and motherhood.
It's worth noting that males also have breast tissue, although it is usually less developed than in females. Male breast tissue consists mainly of adipose tissue and does not typically contain functional mammary glands. However, some men may develop enlarged breast tissue due to conditions such as gynecomastia, which can be caused by hormonal imbalances or certain medications.
Adenofibroma is a rare, benign tumor that occurs most commonly in the salivary glands. It is composed of both glandular tissue (adeno-) and fibrous tissue (-fibroma). These tumors are slow-growing and typically do not spread to other parts of the body.
Adenofibromas can also occur in other areas of the body, such as the skin, where they may be referred to as "fibroepithelial polyps" or "skin tags." In general, adenofibromas are not cancerous and can often be removed surgically. However, it is important to have any new growths or lumps evaluated by a healthcare professional to determine the appropriate course of treatment.
A fibroadenoma is a benign (noncancerous) breast tumor that is most commonly found in women between the ages of 15 and 35, although it can occur at any age. It is composed of glandular and connective tissue. The tumor typically feels firm, smooth, and rubbery, and its size may vary from quite small to over 2 inches in diameter.
Fibroadenomas are usually mobile within the breast tissue, which means they can be moved around easily when touched. They can occur as a single lump or multiple lumps (known as fibroadenomatosis). The exact cause of fibroadenomas is not known, but hormonal factors may play a role in their development.
Fibroadenomas are generally not painful, although some women may experience discomfort or tenderness, especially before their menstrual period. In most cases, fibroadenomas do not require treatment and can be monitored with regular breast exams and imaging studies such as mammography or ultrasound. However, if a fibroadenoma grows larger or becomes uncomfortable, it may be removed through a surgical procedure.
Breast neoplasms refer to abnormal growths in the breast tissue that can be benign or malignant. Benign breast neoplasms are non-cancerous tumors or growths, while malignant breast neoplasms are cancerous tumors that can invade surrounding tissues and spread to other parts of the body.
Breast neoplasms can arise from different types of cells in the breast, including milk ducts, milk sacs (lobules), or connective tissue. The most common type of breast cancer is ductal carcinoma, which starts in the milk ducts and can spread to other parts of the breast and nearby structures.
Breast neoplasms are usually detected through screening methods such as mammography, ultrasound, or MRI, or through self-examination or clinical examination. Treatment options for breast neoplasms depend on several factors, including the type and stage of the tumor, the patient's age and overall health, and personal preferences. Treatment may include surgery, radiation therapy, chemotherapy, hormone therapy, or targeted therapy.
A breast cyst is a fluid-filled sac that forms within the breast tissue. It is a common, benign (non-cancerous) condition and can affect people of any age, but it is more commonly found in women between the ages of 35 and 50. Breast cysts can vary in size and may be asymptomatic or cause discomfort or pain, especially just before menstruation.
Breast cysts are usually diagnosed through a physical examination, breast ultrasound, or mammography. In some cases, a fine-needle aspiration (FNA) may be performed to drain the fluid from the cyst and confirm the diagnosis. If the cyst is small, causes no symptoms, and appears benign on imaging studies, then further treatment may not be necessary. However, if the cyst is large, painful, or has concerning features on imaging studies, then additional diagnostic tests or drainage procedures may be recommended.
It's important to note that while breast cysts are generally harmless, they can sometimes mimic the symptoms of breast cancer. Therefore, any new or unusual changes in the breast should be evaluated by a healthcare professional.
Fibrocystic breast changes
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LUMPS21
- Fibrocystic breast disease is a generalized term for non- malignant lumps in breasts, causing pain. (rxmed.com)
- Fibrocystic breast disease is the most frequent cause of lumps in the breast. (rxmed.com)
- Causes of benign breast disease are unknown, but lumps are probably sustained by estrogen and possibly also related to dietary fat and caffeine intake. (rxmed.com)
- Practice monthly breast self-examination to check breasts for lumps and changes in lumps after diagnosis. (rxmed.com)
- Painful tender breast lump, either solitary or more commonly multiple tender lumps, usually in upper outer quadrants of the breast. (rxmed.com)
- Fluid pooling could then result in fibrocystic changes (benign lumps, cysts, and pain). (drsircus.com)
- You find new or different lumps during your breast self-exam . (medlineplus.gov)
- These lumps can sometimes be obscured by irregularities in the breast associated with the condition. (wikipedia.org)
- She is specifically asked to watch out for new lumps or masses in her breasts. (digitalnaturopath.com)
- Fibrocystic breast disease is a non-cancerous breast condition in which tender lumps can cause pain and discomfort related mainly to a woman's monthly fluctuating hormones. (macarthurmc.com)
- Fibrocystic breast changes often present as multiple swollen, tender lumps in both breasts that tend to start just prior to a woman's period and disappear shortly afterwards. (macarthurmc.com)
- Even those whose lumps remain benign often experience extreme discomfort in the breast. (aljazeera.co.in)
- While some lumps may be cancerous, having breast cysts or fibrocystic breasts doesn't increase your risk of breast cancer, but it is still important to gtet rid of them using listed below suggestions. (fullhealthsecrets.com)
- Oestrogen dominance causes breast lumps because it is a powerful proliferator and its excessive levels stimulate abnormal cells in the breasts and uterus to multiply thus creating fibroids (lumps) in the breast and uterus. (fullhealthsecrets.com)
- Failure to provide enough methyl groups (due to the deficiency of vitamin B12, B6, folate and some other nutrients) leads to raised homocysteine levels and allows oestrogens to accumulate , resulting in hormone imbalance and oestrogen dominance which leads to uterine and breast fibroids, breast lumps, PMS, and increased risk of cancer, heart attacks and strokes. (fullhealthsecrets.com)
- Not only did it not hurt but the results showed less fibrocystic lumps than my right breast. (fullhealthsecrets.com)
- Fibrocystic breast changes are noncancerous lumps or abnormalities in the breast tissue. (lifeextension.com)
- Fibrocystic breast changes are non-cancerous lumps or abnormalities in the breast tissue. (lifeextension.com)
- The symptoms of fibrocystic disease (which is not actually a disease but a common condition) are nodules or lumps in the breasts that can change in size and location. (smartplay.com.au)
- Breast Lumps A breast lump (mass) is a thickening or bump that feels different from surrounding breast tissue. (merckmanuals.com)
- For patient education information, see Breast Lumps and Pain and Breast Self-Exam . (medscape.com)
Risk of fibrocystic breast1
- Drinking alcohol increases the risk of fibrocystic breast changes. (fullhealthsecrets.com)
Lumpy9
- Fibrocystic breasts are painful, lumpy breasts. (medlineplus.gov)
- This may make your breasts feel swollen, lumpy, or painful before or during your period each month. (medlineplus.gov)
- The changes in fibrocystic breast disease are characterised by the appearance of fibrous tissue and a lumpy, cobblestone texture in the breasts. (wikipedia.org)
- Image via Wikipedia Fibrocystic disease of the breast is a condition that is seen in a large percentage of women from ages 30 to 50, in which the breast becomes painful and lumpy, especially during menses. (digitalnaturopath.com)
- Lumpy breast tissue affects more than half of women at some point in their lives. (aljazeera.co.in)
- Presence of lumpy masses or areas of thickening that tend to blend into the surrounding breast tissue. (fullhealthsecrets.com)
- Lumpy breasts are often associated with premenstrual syndrome (PMS), as they appear to be caused by hormonal changes in the body. (smartplay.com.au)
- Fibrocystic breast changes are harmless but potentially uncomfortable symptoms that cause the breasts to feel lumpy or otherwise different in texture due to hormonal fluctuations. (medicalnewstoday.com)
- This is warranted, because fibrocystic breast disease (FBD) can cause lumpy, painful and uncomfortable breasts, while breast cancer may facilitate dis-forming surgery, and numerous deaths each year. (selfgrowth.com)
Symptoms of fibrocystic breast2
- Post-menopausal under hormone replacement therapy have also reported symptoms of fibrocystic breast changes indicating hormones may play a major role. (wikipedia.org)
- This protocol describes the signs and symptoms of fibrocystic breast changes and provides information concerning conventional treatment, novel and emerging strategies, diet and lifestyle considerations, and integrative interventions. (lifeextension.com)
Tenderness6
- Other symptoms are breast tenderness, pain (mastalgia), and discomfort. (logicalimages.com)
- Women with fibrocystic changes may experience a persistent or intermittent aching or breast tenderness related to periodic swelling. (wikipedia.org)
- There is no cure or treatment for this condition, but there are ways to treat the symptoms of breast tenderness and swelling. (macarthurmc.com)
- Breast tenderness which can get worse before menstruation. (fullhealthsecrets.com)
- Chasteberry, also known as Vitex agnus-castus , is commonly used for breast pain, especially premenstrual breast tenderness. (lifeextension.com)
- This type of breast pain usually causes tenderness in both breasts, and it may extend to the armpit. (medicalnewstoday.com)
Cysts or fibrocystic1
- Breast cysts or fibrocystic breast disease are composed of fluid-filled spaces covered by a membrane. (clearwoman.com)
Hormonal6
- Fibrocystic breast changes are common, benign cystic changes in the fibrous breast tissue associated with the female hormonal cycle and occurring prior to menstruation. (logicalimages.com)
- Possible causes of breast pain include hormonal changes, an incorrect bra fit, and infections. (medicalnewstoday.com)
- Tender or swollen breasts are usually related to the hormonal changes that take place before a period. (medicalnewstoday.com)
- Breast pain can also occur due to other hormonal changes, such as those that take place during pregnancy or in the first stage of menopause . (medicalnewstoday.com)
- Accessory or ectopic breast tissue responds to hormonal stimulation and may cause discomfort during menstrual cycles. (medscape.com)
- Hormonal management of fibrocystic disease of the breast. (bvsalud.org)
Menopause1
- Generic Arimidex is used for treating breast cancer in women who have been through menopause, including women with disease progression after tamoxifen therapy. (genericdoctor.com)
Cause fibrocystic2
- In this scenario, breast cells may become damaged and cause fibrocystic breast disease (FBD) or cancer. (selfgrowth.com)
- can cause fibrocystic changes. (merckmanuals.com)
Menstrual cycle4
- Associations of serum levels of sex hormones in follicular and luteal phases of the menstrual cycle with breast tissue characteristics in young women. (reproduct-endo.com)
- When breast pain is related to the menstrual cycle, it is known as cyclic breast pain. (medicalnewstoday.com)
- If a person gets cyclic breast pain, they may also find that at certain times in their menstrual cycle, their usual bras feel too small or are uncomfortable. (medicalnewstoday.com)
- These fluctuations partly explain why breasts are swollen and more sensitive during a particular time of each menstrual cycle. (merckmanuals.com)
Diagnosis3
- Diagnosis involves ruling out breast cancer. (wikipedia.org)
- This is an exclusion diagnosis, mostly done based on the clinical presentation after ruling out breast cancer. (wikipedia.org)
- If you (or a loved one) are dealing with a breast cancer diagnosis, or breast cancer treatment or recovery, check this list of related medical terms to better understand what it's all about. (ucsfhealth.org)
Cancer61
- Any lump or pain in the breast raises the spectre of breast cancer. (healthy.net)
- The more fat you have, the higher your estrogen and therefore the higher your risk of breast cancer will be. (healthy.net)
- These foods cause a surge in insulin and women with the highest insulin levels have a 283% higher incidence of breast cancer. (healthy.net)
- Avoid eating red meat because it substantially increases the risk of breast cancer. (healthy.net)
- Soy is a superstar in your arsenal against breast cancer, and has been a food stable in the Asian diet for thousands of years. (healthy.net)
- Many herbs used in Traditional Chinese Medicine, as well as other common spices and herbs including ginseng, licorice root, rosemary, black cohosh, hops, and chaste tree berry are effective natural medicines against breast cancer. (healthy.net)
- Two published studies have shown that women who wear bras have much higher breast cancer rates than women who don't wear a bra. (drsircus.com)
- Singer and Grismaijer, a husband and wife research team, published a study of almost 5000 women in the book Dressed to Kill: The Link Between Breast Cancer and Bras[ 1 ] . (drsircus.com)
- They found that the more hours per day that woman wear bras, the higher their rates of breast cancer. (drsircus.com)
- This prevents the natural flushing out of accumulated cancer-causing wastes and toxins from the breast. (drsircus.com)
- Women who wore their bras 24 hours per day had a 3 out of 4 chance of developing breast cancer (in their study, n=2056 for the cancer group and n=2674 for the standard group). (drsircus.com)
- Women who wore bras rarely or never had a 1 out of 168 chance of getting breast cancer. (drsircus.com)
- Fibrocystic breast changes do not change your risk for breast cancer. (medlineplus.gov)
- If you are over 40, ask your provider how often you should have a mammogram to screen for breast cancer. (medlineplus.gov)
- Fibrocystic breast changes do not generally increase your risk for breast cancer. (medlineplus.gov)
- However, if you have a family history of breast cancer and fibrocystic changes, there is a small increase in the risk. (medlineplus.gov)
- These are normal breast changes, not associated with cancer. (wikipedia.org)
- Nipple fluid aspiration can be used as a classification cyst type method (and to some extent improve breast cancer risk prediction) but is rarely used in practice. (wikipedia.org)
- Women with fibrocystic breasts are thought to have two to eight times greater risk of developing breast cancer. (aljazeera.co.in)
- There's evidence of link between bras and breast cancer. (fullhealthsecrets.com)
- This can be contrasted to breast cancer or a breast fibroadenomas which are both painless. (clearwoman.com)
- However, rarely breast cancer can also be painful and not painless. (clearwoman.com)
- But breast cancer is usually painless. (clearwoman.com)
- There is some debate as to whether or not fibrocystic breast disease precedes or predicts breast cancer. (clearwoman.com)
- Some argue that breast cysts have nothing to do with breast cancer. (clearwoman.com)
- Some argue that breast cysts are the harbinger of breast cancer. (clearwoman.com)
- However, in my mind xenoestrogens cause both breast cancer and fibrocystic breast disease. (clearwoman.com)
- Therefore, it is xenoestrogens that are predictive of breast cancer and fibrocystic breast disease. (clearwoman.com)
- Instead of wondering whether fibrocystic breast disease predicts breast cancer what you should be looking at are the intake of xenoestrogens to predict breast cancer and fibrocystic breast disease. (clearwoman.com)
- Bespalov, V.G., Travina, M.L. "Fibrocystic disease and the risk of breast cancer (literature review). (reproduct-endo.com)
- Breast cancer risk in hyperprolactinemia: a population-based cohort study and meta-analysis of the literature. (reproduct-endo.com)
- It is important for women who notice changes in their breast tissue to let their doctor know right away so that breast cancer or another serious disease can be ruled out. (lifeextension.com)
- Breast pain is not commonly a symptom of breast cancer , but if a person has pain alongside other breast changes, such as a lump or discharge, they should speak with a doctor. (medicalnewstoday.com)
- Both surgery and radiation therapy for breast cancer can cause scar tissue formation. (medicalnewstoday.com)
- Two drugs, adriamycin and cytoxan, commonly used to treat breast cancer patients. (ucsfhealth.org)
- Treatment that is given before there is any indication that the cancer has spread to prevent or delay the development of metastatic breast cancer administered after surgery and/or radiation. (ucsfhealth.org)
- Generic name for Arimidex, a hormone therapy for advanced breast cancer. (ucsfhealth.org)
- Brand name for anastrazole a hormone therapy for advanced breast cancer. (ucsfhealth.org)
- Benign microscopic breast changes known as atypical hyperplasia may increase a woman's risk of developing breast cancer. (ucsfhealth.org)
- Japanese women have very low rates of breast cancer and consume high levels of iodine. (westonaprice.org)
- This observation has led to the theory that high iodine levels in the Japanese diet, rich in seaweed and seafood, provide protection against breast cancer and other diseases of the breast. (westonaprice.org)
- Proponents of this theory note that today one in seven American women (almost 15 percent) will develop breast cancer during her lifetime. (westonaprice.org)
- Thirty years ago, when iodine consumption was twice as high as it is now (480 mcg per day) one in twenty women developed breast cancer. (westonaprice.org)
- The correlation of iodine deficiency with breast cancer is strengthened by reports in the scientific literature. (westonaprice.org)
- Women with a history of breast cancer are almost three times more likely to develop thyroid cancer than women with no such history, and there is a geographic correlation between the incidence of goiter and breast cancer. (westonaprice.org)
- There is so much misinformation about the dangers and prevalence of breast cancer highlighted by the media that the prevention of the disease is still buried in myth. (selfgrowth.com)
- Remember this link has not been conclusively proven yet as there are few studies on bra wearing and breast cancer, the results of existing research are troubling. (selfgrowth.com)
- In the book Dressed to Kill: the link between Breast Cancer and Bras, one of the studies suggests the link between bras and breast cancer is about three times stronger than the link between cigarette smoking and breast cancer. (selfgrowth.com)
- Women who wore bras for over 12 hours per day, but did not sleep in them were 21 times more likely to develop breast cancer than women who removed their bras within 12 hours. (selfgrowth.com)
- Another study, published in the European Journal of Cancer, found that premenopausal women who did not wear bras carried half the risk of breast cancer compared with bra wearers. (selfgrowth.com)
- This is not to say that breast cancer and FBD will be totally eliminated if women stopped wearing bras. (selfgrowth.com)
- Too much 16-hydroxyestrogen has been associated with lupus, other autoimmune diseases, and breast cancer. (natural-fertility-info.com)
- Studies have shown that women taking replacement estrogen have a 2 to 8 times higher risk of developing breast cancer, ovarian cancer and endometrial cancer than women who do not take estrogen. (health-science.com)
- If left untreated, PCOS can increase the risk of diabetes, heart disease, hypertension (high blood pressure), eating disorders, endometrial hyperplasia and endometrial cancer. (mum.org)
- Fibrocystic changes of the breast (formerly called fibrocystic breast disease) include breast pain, cysts, and lumpiness that are not due to cancer. (merckmanuals.com)
- In contrast, breast cancer can mean. (merckmanuals.com)
- Breast Cancer Breast cancer occurs when cells in the breast become abnormal and divide uncontrollably. (merckmanuals.com)
- Breast cancer usually starts in the glands that produce milk (lobules) or the tubes (ducts) that carry. (merckmanuals.com)
- Fibrocystic changes may make the breasts appear dense on mammograms and thus may make breast cancer more difficult to detect. (merckmanuals.com)
- Aromasin is used to treat breast cancer in postmenopausal women. (genericdoctor.com)
- Breast Cancer Cancer is when cells grow abnormally. (msdmanuals.com)
Estrogen4
- There is evidence that iodine deficiency contributes to fibrocystic breast changes by enhancing breast tissue sensitivity to estrogen. (wikipedia.org)
- During adult life the breast undergoes constant activity, especially under the influence of the hormones estrogen and progesterone. (digitalnaturopath.com)
- The exact cause of fibrocystic breast changes isn't known, but experts suspect that it happens in response to the reproductive hormones - estrogen and progesterone - which affect the breast tissue. (aljazeera.co.in)
- Aromasin lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. (genericdoctor.com)
Tissue14
- Fibrocystic breast changes occur when thickening of breast tissue (fibrosis) and fluid-filled cysts develop in one or both breasts. (medlineplus.gov)
- For women under 35, a breast ultrasound may be used to look more closely at breast tissue. (medlineplus.gov)
- These hormones directly affect the breast tissue by causing cells to grow and multiply. (wikipedia.org)
- What is it: The breast contains a lot of glandular tissue. (digitalnaturopath.com)
- These changes include fibrosis or scar tissue formation, cystic changes (fluid filled vesicles or sacs within the breast) and inflammatory changes including the accumulation of fluid within the breast. (digitalnaturopath.com)
- If the body holds on to extra fluid, the breast tissue will too because cysts of fibrocystic breasts are primarily fluid-filled sacs. (aljazeera.co.in)
- Fibrosis means having a breast tissue that's scar-like. (fullhealthsecrets.com)
- Between 50% and 90% of women will experience benign changes in their breast tissue during their lifetime, with the 30s and 40s being the most common age of occurrence. (lifeextension.com)
- If changes in a woman's breast tissue are determined to be benign and do not cause symptoms, then no treatment is necessary. (lifeextension.com)
- Fibrocystic breasts are very common: estimates suggest that between 50% and 90% of all women will experience benign changes in their breast tissue during their lifetime (Jones 2011). (lifeextension.com)
- Bras can cause breast pain if they are too tight or they contain an underwire that digs into the skin or breast tissue. (medicalnewstoday.com)
- Pinpoint cancers in women who have very dense breast tissue or breast implants. (drugs.com)
- Athelia (ie, absence of nipples) and amastia (ie, absence of breast tissue) may occur bilaterally or unilaterally. (medscape.com)
- Mastitis neonatorum or infections of the breast tissue may also occur during the newborn period. (medscape.com)
Tumors3
- In response to a request from the director of Mainstreet Enterprises (SIC-3273), a nonprofit rehabilitation sheltered workshop in Lebanon, Indiana, an evaluation was made of the occurrence of benign breast tumors among female workers exposed to concrete dust during packaging of dry powdered concrete mortar mix (Fix-Crete). (cdc.gov)
- No significant differences in the prevalence of benign breast tumors was noted in supervisors working on the concrete powder process when compared to those who did not work in this area. (cdc.gov)
- No evidence was found to link the occurrence of benign breast tumors to chemical exposures at the facility. (cdc.gov)
Bilateral2
- Certain lady after wathiching a video about natural remedies and poultices by Barbara O'Neil decided to try castor oil, and being sutisfied with its effectiveness wrote the following testimonial: "I am a 64 year old female with extreme bilateral fibrocystic disease of the breast . (fullhealthsecrets.com)
- What is bilateral fibrocystic disease of breasts? (healthtap.com)
Lump5
- You may have a lump in the same area of the breast that becomes larger before each period and returns to its original size afterward. (medlineplus.gov)
- This type of lump is common with fibrocystic breasts. (medlineplus.gov)
- You may need further tests if a lump was found during a breast exam or your imaging result was abnormal. (medlineplus.gov)
- A cyst is a fluid-filled lump that can move around in the breast. (fullhealthsecrets.com)
- So if the lump in the breast is painful and occurs at the same time of the cycle every month, it is normally fibrocystic breast disease or breast cysts. (clearwoman.com)
Fibroadenoma2
- Fibrocystic breast disease, also known as cystic mastitis or fibroadenoma, is not only common, but also worrying. (healthy.net)
- Breast disorders occurring in pediatric patients range from congenital conditions to neonatal infections and from benign disorders such as fibroadenoma in females and gynecomastia in males to breast carcinoma and rhabdomyosarcoma . (medscape.com)
Mammogram1
- See your doctor for a breast examination and, if recommended, a mammogram. (smartplay.com.au)
Mastalgia2
- Some research shows that the flax plant is the best plant for a decrease of pain (mastalgia) in fibrocystic breasts. (aljazeera.co.in)
- Breast pain, or mastalgia, is very common. (medicalnewstoday.com)
Painful2
- Breast cysts are usually painful. (clearwoman.com)
- Mastitis refers to painful inflammation of the breast. (merckmanuals.com)
Abnormal1
- Fatty acid profiles may be abnormal in women with fibrocystic breast disease. (diagnose-me.com)
Mammography2
- Mammography is usually the first imaging test to be ordered when unusual breast changes are found during a clinical breast examination. (wikipedia.org)
- A diagnostic mammography consists of a series of X-rays that provide clear and specific visualization of areas in the breast. (wikipedia.org)
Cancerous1
- Overview of Breast Disorders Breast disorders may be noncancerous (benign) or cancerous (malignant). (merckmanuals.com)
Woman's1
- Fibrocystic disease of the breast is the result of many physiological changes that take place in a woman's breast over a long period of time. (digitalnaturopath.com)
Women25
- More than half of women experience fibrocystic breast disease at some part of their lives. (todays-woman.net)
- At least 50% of women have benign breast disease during their lifetime. (rxmed.com)
- In fact, some women actually find that they sag less, presumably because their chest ligaments and muscles improve their tone and strength when they must do the work of supporting the breasts (one doctor said it is a matter of 'Use it or lose it. (drsircus.com)
- Over 90% of women with fibrocystic changes find improvement when they stop wearing their brassieres. (drsircus.com)
- Ken L. Smith , Breast Health Facilitator for ACS explains on his website that before brassieres were made commercially available, some women wore corsets that literally bound the body very tightly, compressing the internal organs and forcing them into new positions. (drsircus.com)
- Many women experience these normal breast changes, usually around their period. (medlineplus.gov)
- Between the ages 30 to 50, many women complain of pain and lumpiness in the breasts usually associated with menses. (digitalnaturopath.com)
- This disorder called fibrocystic breasts-once called fibrocystic breast disease- is common for women of all ages, especially between 30 and 50 years. (aljazeera.co.in)
- Beyond the above symptoms, women with fibrocystic breasts may also experience discomfort under the arms and discharge from the nipple-these are all benign. (aljazeera.co.in)
- Nevertheless, some women have reported that limiting caffeine consumption improves breast pain. (aljazeera.co.in)
- Women suffering from fibrocystic breast disease should consider increasing flaxseeds in their diet. (aljazeera.co.in)
- Breast cysts and fibrocystic breast changes are common noncancerous conditions that affect mostly premenopausal women. (fullhealthsecrets.com)
- More than half of women experience breast cysts and fibrocystic breast changes at some point in their lives. (fullhealthsecrets.com)
- to establish the clinical efficacy of 1.0% micronized progesterone gel Progestogel® at the preconception stage in order to prevent lactation disorders in women with fibrocystic breast disease (FBD). (reproduct-endo.com)
- Examination of this group of patients in the long-term period (6 month after the end of lactation) showed no clinical manifestations of the breast disease (pain syndrome and edema) in 24 (80.0%) women and regression of ultrasound signs of FBD in 21 (70.0%) patients. (reproduct-endo.com)
- Manifestation of both clinical and echographic signs of the breast disease was diagnosed in 26 (86.7%) women in the comparison group. (reproduct-endo.com)
- There are several actions women can take on their own that may help ease symptoms caused by fibrocystic breast changes and reduce the incidence of these conditions. (lifeextension.com)
- Women who consumed the most food sources of lignans were 52% less likely to have benign breast changes than those with the lowest consumption of these foods. (lifeextension.com)
- According to a 2021 article, 60-70% of women report less breast pain when they wear a sports bra during exercise. (medicalnewstoday.com)
- Do older women (60+ years) get fibrocystic breasts? (healthtap.com)
- Women around the world are concerned about the health of their breast. (selfgrowth.com)
- What are some questions women asked about breast protection? (selfgrowth.com)
- Tamoxifen, either alone or combined with chemotherapy, prolongs disease-free survival when administered for 24 months as adjuvant therapy to postmenopausal women with axillary lymph node metastases. (pharmacology2000.com)
- They described these women and their "new disease" in the American Journal of Obstetrics and Gynecology. (mum.org)
- Most women have some general lumpiness in the breasts, usually in the upper outer part, near the armpit. (merckmanuals.com)
Pain17
- Depending on the severity, a woman with fibrocystic breast disease may or may not notice or experience pain. (todays-woman.net)
- Mild anti-inflammatory or analgesic may be used for breast pain and inflammation. (logicalimages.com)
- Fibrocystic breast changes is a condition of the breasts where there may be pain, breast cysts, and breast masses. (wikipedia.org)
- By the age of 30, multiple small cysts and breast pain may arise. (wikipedia.org)
- Treatment of Symptoms There is a certain amount of pain and inflammation associated with fibrocystic breast disease. (digitalnaturopath.com)
- Large amounts of caffeine, a stimulant found in coffee and many teas and colas, can cause changes in hormone levels that may affect the formation of breast cysts or cause breast pain. (aljazeera.co.in)
- Research on limiting caffeine consumption as a treatment for breast pain has yielded mixed results and clinical studies have not shown consistent findings. (aljazeera.co.in)
- I'm a 33 yr old Hispanic female who 5 yrs ago had surgery removing 2 cysts in my breast that were causing me a lot of pain . (clearwoman.com)
- Vitamin E was shown to be effective in reducing the most severe premenstrual breast pain in a clinical trial. (lifeextension.com)
- Evening primrose oil, which contains GLA, was found to reduce the most severe premenstrual breast pain when taken at a daily dose of 3 g for six months. (lifeextension.com)
- Pain in the breast affects approximately two-thirds of females during their reproductive years, and it is one of the most frequent complaints of those aged 15-40 years. (medicalnewstoday.com)
- Cyclic breast pain can be part of a set of symptoms that occur before a period, known as premenstrual syndrome (PMS), or it may occur on its own. (medicalnewstoday.com)
- Some medications can contribute to the development of breast pain. (medicalnewstoday.com)
- People with breast pain should speak with a doctor to find out whether any of their medications could be causing their symptoms. (medicalnewstoday.com)
- How can i relieve pain from my fibrocystic breasts? (healthtap.com)
- Would it be fine to squeeze the breasts to relieve fibrocystic pain? (healthtap.com)
- Fibrocystic changes are a set of breast symptoms that include pain, cysts (small, fluid-filled sacs), and general lumpiness in your breasts. (msdmanuals.com)
Inflammation1
- Mastitis is the term for inflammation or swelling in the breasts. (medicalnewstoday.com)
Incidence2
- Some studies indicate that ingestion of methylxanthine- containing substances (e.g. coffee, tea, cola and chocolates), and smoking cigarettes are associated with a higher incidence and greater extent of fibrocystic breast disease. (rxmed.com)
- Increased consumption of soy foods is significantly associated with a lower incidence of fibrocystic breasts. (aljazeera.co.in)
Menstruation2
- Examine breasts carefully each month, a few days after the onset of menstruation. (rxmed.com)
- It is thought that hormones made in the ovaries during menstruation can trigger these breast changes. (medlineplus.gov)
Treatment6
- The treatment of fibrocystic breast changes is two pronged. (digitalnaturopath.com)
- Ovsyannikova, T.V. «The program of examination and treatment of patients with diseases of the mammary glands in the practice of an obstetrician-gynecologist. (reproduct-endo.com)
- Re: Fibrocystic Breast Disease - Treatment and Pre. (curezone.com)
- I plan on starting the Borax treatment- I have RA, allergies, An Autoimmune disease. (earthclinic.com)
- Following the treatment used to control local disease, adjuvant combination chemotherapy is given to reduce the rate of recurrence and improve survival in pre- and postmenopausal node-positive patients. (pharmacology2000.com)
- Following the treatment used to control local disease, adjuvant endocrine therapy with tamoxifen alone is given to reduce the rate of recurrence and improve survival in postmenopausal patients with lymph node involvement and positive hormone receptors. (pharmacology2000.com)
Ultrasound1
- Ultrasound findings of the physiological changes and most common breast diseases during pregnancy and lactation. (reproduct-endo.com)
Fibrosis1
- Fibrocystic changes include fibroadenomas, fibrosis, and papillomas of the breast. (wikipedia.org)
Ovarian2
- Is there a connection between fibrocystic breast disease, ovarian cysts and iodine deficiency? (fertilityfriday.com)
- Polycystic ovarian syndrome was first identified by Irving Stein and Michael Leventhal in 1935, and the condition was originally called Stein-Leventhal disease. (mum.org)
Benign breast5
- Therefore the term benign breast disease or fibrocystic condition would be more appropriate. (rxmed.com)
- Routine laboratory tests are not helpful in evaluation of benign breast disease. (rxmed.com)
- Benign breast conditions. (medlineplus.gov)
- A clinical approach to benign breast lesions in female adolescents. (reproduct-endo.com)
- Plasma fatty acid profiles in benign breast disorders. (diagnose-me.com)
Iodine3
- Fibrocystic breast disease or breast cysts are easily eliminated in 3 to 4 months by avoiding xenoestrogens and taking natural progesterone and iodine. (clearwoman.com)
- While the thyroid gland contains the body's highest concentration of iodine, the salivary glands, brain, cerebrospinal fluid, gastric mucosea, breasts, ovaries and a part of the eye also concentrate iodine. (westonaprice.org)
- In the brain, iodine is found in the choroid plexus, the area on the ventricles of the brain where cerebrospinal fluid (CSF) is produced, and in the substantia nigra, an area associated with Parkinson's disease. (westonaprice.org)
Mammograms2
- Fibrocystic changes can make physical examinations and mammograms difficult to interpret. (rxmed.com)
- If your breast exams and mammograms are normal, you do not need to worry about your symptoms. (medlineplus.gov)
Noncancerous breast1
- Fibrocystic breast disease is the most common type of noncancerous breast condition. (medicalnewstoday.com)
20211
- 2021. https://www.tabers.com/tabersonline/view/Tabers-Dictionary/739647/all/fibrocystic_breast_change. (tabers.com)
Cancers1
- Most breast cancers are adenocarcinomas. (ucsfhealth.org)
Condition4
- Formerly called fibrocystic breast disease, this common condition is, in fact, not a disease. (medlineplus.gov)
- This condition is historically called fibrocystic breast disease. (digitalnaturopath.com)
- Although research hasn't found proof of a link between dietary factors and fibrocystic breast changes , if you have this condition, you might adopt the below dietary alterations to see if it helps. (aljazeera.co.in)
- or some combination of these symptoms-a condition called fibrocystic changes. (merckmanuals.com)
Sexually Transmit2
- Patients should be counseled that this product does not protect against HIV infection (AIDS) and other sexually transmitted diseases. (nih.gov)
- Kelnor is an effective method of birth control, but it does not avoid the spread of human immunodeficiency virus (HIV) and other sexually transmitted diseases. (familywize.org)