Foot Ulcer
Diabetic Foot
Foot
Stomach Ulcer
Leg Ulcer
Peptic Ulcer
Pressure Ulcer
Skin Ulcer
Skin Care
Diabetic Neuropathies
Arthropathy, Neurogenic
Foot Deformities, Acquired
Shoes
Peptic Ulcer Hemorrhage
Hyperbaric Oxygenation
Debridement
Foot Deformities
Peptic Ulcer Perforation
Foot Bones
Osteomyelitis
Skin, Artificial
Buruli Ulcer
Foot Joints
Foot Deformities, Congenital
Podiatry
Granulation Tissue
Honey
Bandages, Hydrocolloid
Negative-Pressure Wound Therapy
Diabetes Complications
Orthopedic Equipment
Varicose Ulcer
Pressure
Nursing Assessment
Treatment Outcome
Vacuum
Hand, Foot and Mouth Disease
Medicare Part A
Prospective Studies
Forms and Records Control
Diabetes Mellitus, Type 2
Anti-Ulcer Agents
Physical Examination
Helicobacter pylori
Administration, Topical
Ischemia
Follow-Up Studies
Foot Orthoses
Helicobacter Infections
Diabetes Mellitus, Type 1
Exudates and Transudates
Diabetes Mellitus
Tarsal Bones
Skin
France
Mycobacterium ulcerans
Angiogenesis Inducing Agents
Risk Factors
Peripheral Arterial Disease
Washington
Evidence of partial protection against foot-and-mouth disease in cattle immunized with a recombinant adenovirus vector expressing the precursor polypeptide (P1) of foot-and-mouth disease virus capsid proteins. (1/110)
A recombinant live vector vaccine was produced by insertion of cDNA encoding the structural proteins (P1) of foot-and-mouth disease virus (FMDV) into a replication-competent human adenovirus type 5 vaccine strain (Ad5 wt). Groups of cattle (n = 3) were immunized twice, by the subcutaneous and/or intranasal routes, with either the Ad5 wt vaccine or with the recombinant FMDV Ad5-P1 vaccine. All animals were challenged by intranasal instillation of FMDV 4 weeks after the second immunizations. In the absence of a detectable antibody response to FMDV, significant protection against viral challenge was seen in all of the animals immunized twice by the subcutaneous route with the recombinant vaccine. The observed partial protection against clinical disease was not associated with a reduction in titre of persistent FMDV infections in the oropharynx of challenged cattle. (+info)Incidence, outcomes, and cost of foot ulcers in patients with diabetes. (2/110)
OBJECTIVE: To determine the incidence of foot ulcers in a large cohort of patients with diabetes, the risk of developing serious complications after diagnosis, and the attributable cost of care compared with that in patients without foot ulcers. RESEARCH DESIGN AND METHODS: Retrospective cohort study of patients with diabetes in a large staff-model health maintenance organization from 1993 to 1995. Patients with diabetes were identified by algorithm using administrative, laboratory, and pharmacy records. The data were used to calculate incidence of foot ulcers, risk of osteomyelitis, amputation, and death after diagnosis of foot ulcer, and attributable costs in foot ulcer patients compared with patients without foot ulcers. RESULTS: Among 8,905 patients identified with type 1 or type 2 diabetes, 514 developed a foot ulcer over 3 years of observation (cumulative incidence 5.8%). On or after the time of diagnosis, 77 (15%) patients developed osteomyelitis and 80 (15.6%) required amputation. Survival at 3 years was 72% for the foot ulcer patients versus 87% for a group of age- and sex-matched diabetic patients without foot ulcers (P < 0.001). The attributable cost for a 40- to 65-year-old male with a new foot ulcer was $27,987 for the 2 years after diagnosis. CONCLUSIONS: The incidence of foot ulcers in this cohort of patients with diabetes was nearly 2.0% per year. For those who developed ulcers, morbidity, mortality, and excess care costs were substantial compared with those for patients without foot ulcers. The results appear to support the value of foot-ulcer prevention programs for patients with diabetes. (+info)Causal pathways for incident lower-extremity ulcers in patients with diabetes from two settings. (3/110)
OBJECTIVE: To determine the frequency and constellations of anatomic, pathophysiologic, and environmental factors involved in the development of incident diabetic foot ulcers in patients with diabetes and no history of foot ulcers from Manchester, U.K., and Seattle, Washington, research settings. RESEARCH DESIGN AND METHODS: The Rothman model of causation was applied to the diabetic foot ulcer condition. The presence of structural deformities, peripheral neuropathy, ischemia, infection, edema, and callus formation was determined for diabetic individuals with incident foot ulcers in Manchester and Seattle. Demographic, health, diabetes, and ulcer data were ascertained for each patient. A multidisciplinary group of foot specialists blinded to patient identity independently reviewed detailed abstracts to determine component and sufficient causes present and contributing to the development of each patient's foot ulcer. A modified Delphi process assisted the group in reaching consensus on component causes for each patient. Estimates of the proportion of ulcers that could be ascribed to each component cause were computed. RESULTS: From among 92 study patients from Manchester and 56 from Seattle, 32 unique causal pathways were identified. A critical triad (neuropathy, minor foot trauma, foot deformity) was present in > 63% of patient's causal pathways to foot ulcers. The components edema and ischemia contributed to the development of 37 and 35% of foot ulcers, respectively. Callus formation was associated with ulcer development in 30% of the pathways. Two unitary causes of ulcer were identified, with trauma and edema accounting for 6 and < 1% of ulcers, respectively. The majority of the lesions were on the plantar toes, forefoot, and midfoot. CONCLUSIONS: The most frequent component causes for lower-extremity ulcers were trauma, neuropathy, and deformity, which were present in a majority of patients. Clinicians are encouraged to use proven strategies to prevent and decrease the impact of modifiable conditions leading to foot ulcers in patients with diabetes. (+info)Lower-extremity amputation in diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers. (4/110)
OBJECTIVE: To identify risk factors for lower-extremity amputation (LEA) in individuals with diabetes and to estimate the incidence of LEA. RESEARCH DESIGN AND METHODS: This is a prospective study of 776 U.S. veterans in a general medicine clinic in Seattle, Washington. The outcome was first LEA during follow-up. Potential risk factors evaluated in proportional hazards models included, among others, peripheral vascular disease (PVD), sensory neuropathy, former LEA, foot deformities and ulcers, diabetes duration and treatment, and hyperglycemia. RESULTS: Associated with an increased risk for LEA were PVD defined as transcutaneous oxygen < or = 50 mmHg (relative risk [RR] = 3.0, 95% CI 1.3-7.1), insensitivity to monofilament testing (RR = 2.9, odds ratio = 1.1-7.8), lower-extremity ulcers (RR = 2.5, CI 1.1-5.4), former LEA, and treatment with insulin when controlling for duration of diabetes and other factors in the model. PVD defined as absent or diminished lower-extremity pulses or an ankle arm index < or = 0.8 was also associated with a significantly higher risk of LEA in separate models. Foot ulcers were associated with an increased ipsilateral risk of amputation. The age-adjusted incidence among men only for LEA standardized to the 1991 U.S. male diabetic population was 11.3/1,000 patient-years. CONCLUSIONS: This prospective study shows that peripheral sensory neuropathy, PVD, foot ulcers (particularly if they appear on the same side as the eventual LEA), former amputation, and treatment with insulin are independent risk factors for LEA in patients with diabetes. (+info)A prospective study of risk factors for diabetic foot ulcer. The Seattle Diabetic Foot Study. (5/110)
OBJECTIVE: Little prospective research exists on risk factors for diabetic foot ulcer that considers the independent effects of multiple potential etiologic agents. We prospectively studied the effects of diabetes characteristics, foot deformity, behavioral factors, and neurovascular function on foot ulcer risk among 749 diabetic veterans with 1,483 lower limbs. RESEARCH DESIGN AND METHODS: Eligible subjects included all diabetic enrollees of a general internal medicine clinic without foot ulcer, of whom 83% agreed to participate. Baseline assessment included history and lower-limb physical examination, tests for sensory and autonomic neuropathy, and measurements of macro- and microvascular perfusion in the foot. Subjects were followed for the occurrence of a full thickness skin defect on the foot that took > 14 days to heal, with a mean follow-up of 3.7 years. RESULTS: Using stepwise Cox regression analysis, the following factors were independently related to foot ulcer risk: foot insensitivity to the 5.07 monofilament (relative risk [95% CI]) 2.2 (1.5-3.1), past history of amputation 2.8 (1.8-4.3) or foot ulcer 1.6 (1.2-2.3), insulin use 1.6 (1.1-2.2), Charcot deformity 3.5 (1.2-9.9), 15 mmHg higher dorsal foot transcutaneous PO2 0.8 (0.7-0.9), 20 kg higher body weight 1.2 (1.1-1.4), 0.3 higher ankle-arm index 0.8 (0.7-1.0), poor vision 1.9 (1.4-2.6), and 13 mmHg orthostatic blood pressure fall 1.2 (1.1-1.5). Higher ulcer risk was associated with hammer/claw toe deformity and history of laser photocoagulation in certain subgroups. Unrelated to foot ulcer risk in multivariate models were diabetes duration and type, race, smoking status, diabetes education, joint mobility, hallux blood pressure, and other foot deformities. CONCLUSIONS: Certain foot deformities, reduced skin oxygenation and foot perfusion, poor vision, greater body mass, and both sensory and autonomic neuropathy independently influence foot ulcer risk, thereby providing support for a multifactorial etiology for diabetic foot ulceration. (+info)Microcirculatory investigations to determine the effect of spinal cord stimulation for critical leg ischemia: the Dutch multicenter randomized controlled trial. (6/110)
PURPOSE: Patients with non-reconstructable critical limb ischemia generally undergo medical treatment only to prevent or postpone amputation. There is some evidence that spinal cord stimulation (SCS) stimulates ischemic wound healing. Thus, this could benefit limb survival through improved skin perfusion. We investigated the effect of SCS versus conservative treatment on skin microcirculation in relation to treatment outcome in patients with non-reconstructable critical limb ischemia. METHODS: Standard medical treatment plus SCS was compared with only standard medical treatment in a multicenter randomized controlled trial comprised of 120 patients with surgically non-reconstructable chronic rest pain or ulceration. We investigated skin microcirculation by means of capillary microscopy, laser Doppler perfusion, and transcutaneous oxygen measurements in the foot. The microcirculatory status just before treatment was classified in three categories (poor, intermediate, and good) and was related to limb survival after a minimum follow-up period of 18 months. RESULTS: Clinical parameters, peripheral blood pressures, and limb survival rates showed no significant differences between the SCS and standard groups during the follow-up period. In both treatment groups, amputation frequency after 18 months was high in patients with an initially poor microcirculatory skin perfusion (SCS 80% vs standard treatment 71%; NS) and low in those with a good skin perfusion (29% vs 11 %, respectively; NS). In patients with an intermediate skin microcirculation amputation, frequency was twice as low in patients additionally treated with SCS as in the standard treatment group (48% vs 24%; P =.08). In these patients, microcirculatory reactive hyperemia during the follow-up period reduced in the standard group but not in the SCS group (P <.01). CONCLUSION: Selection on the basis of the initial microcirculatory skin perfusion identifies patients in whom SCS can improve local skin perfusion and limb survival. (+info)Efficacy of dorsal pedal artery bypass in limb salvage for ischemic heel ulcers. (7/110)
PURPOSE: Although pedal artery bypass has been established as an effective and durable limb salvage procedure, the utility of these bypass grafts in limb salvage, specifically for the difficult problem of heel ulceration, remains undefined. METHODS: We retrospectively reviewed 432 pedal bypass grafts placed for indications of ischemic gangrene or ulceration isolated to either the forefoot (n = 336) or heel (n = 96). Lesion-healing rates and life-table analysis of survival, patency, and limb salvage were compared for forefoot versus heel lesions. Preoperative angiograms were reviewed to evaluate the influence of an intact pedal arch on heel lesion healing. RESULTS: Complete healing rates for forefoot and heel lesions were similar (90.5% vs 86.5%, P =.26), with comparable rates of major lower extremity amputation (9.8% vs 9.3%, P =.87). Time to complete healing in the heel lesion group ranged from 13 to 716 days, with a mean of 139 days. Preoperative angiography demonstrated an intact pedal arch in 48.8% of the patients with heel lesions. Healing and graft patency rates in these patients with heel lesions were independent of the presence of an intact arch, with healing rates of 90.2% and 83.7% (P =.38) and 2-year patency rates of 73.4% and 67.0% in complete and incomplete pedal arches, respectively. Comparison of 5-year primary and secondary patency rates between the forefoot and heel lesion groups were essentially identical, with primary rates of 56.9% versus 62.1% (P =.57) and secondary rates of 67.2% versus 60.3% (P =.50), respectively. CONCLUSION: Bypass grafts to the dorsalis pedis artery provide substantial perfusion to the posterior foot such that the resulting limb salvage and healing rates for revascularized heel lesions is excellent and comparable with those observed for ischemic forefoot pathology. (+info)A case of bilateral heel ulcers associated with hydroxyurea therapy for chronic myelogenous leukemia. (8/110)
Bilateral heel skin ulcers developed in a 50-year-old male in the chronic phase of chronic myelogenous leukemia who had been receiving hydroxyurea (HU) therapy for 3 years. Histological examination showed perivascular lymphocytic inflammation without vasculitis. After interruption of HU administration, the heel ulcers were completely resolved within 2 months. The clinical course strongly suggested that the heel ulcers were induced by long-term HU therapy. (+info)A foot ulcer is a wound or sore on the foot that occurs most commonly in people with diabetes, but can also affect other individuals with poor circulation or nerve damage. These ulcers can be challenging to heal and are prone to infection, making it essential for individuals with foot ulcers to seek medical attention promptly.
Foot ulcers typically develop due to prolonged pressure on bony prominences of the foot, leading to breakdown of the skin and underlying tissues. The development of foot ulcers can be attributed to several factors, including:
1. Neuropathy (nerve damage): This condition causes a loss of sensation in the feet, making it difficult for individuals to feel pain or discomfort associated with pressure points, leading to the formation of ulcers.
2. Peripheral artery disease (PAD): Reduced blood flow to the lower extremities can impair wound healing and make the body more susceptible to infection.
3. Deformities: Structural foot abnormalities, such as bunions or hammertoes, can cause increased pressure on specific areas of the foot, increasing the risk of ulcer formation.
4. Poorly fitting shoes: Shoes that are too tight, narrow, or ill-fitting can create friction and pressure points, contributing to the development of foot ulcers.
5. Trauma: Injuries or trauma to the feet can lead to the formation of ulcers, particularly in individuals with neuropathy who may not feel the initial pain associated with the injury.
6. Foot care neglect: Failure to inspect and care for the feet regularly can result in undetected wounds or sores that progress into ulcers.
Foot ulcers are classified based on their depth, severity, and extent of tissue involvement. Proper assessment, treatment, and prevention strategies are crucial in managing foot ulcers and minimizing the risk of complications such as infection, gangrene, and amputation.
The term "diabetic foot" refers to a condition that affects the feet of people with diabetes, particularly when the disease is not well-controlled. It is characterized by a combination of nerve damage (neuropathy) and poor circulation (peripheral artery disease) in the feet and lower legs.
Neuropathy can cause numbness, tingling, or pain in the feet, making it difficult for people with diabetes to feel injuries, cuts, blisters, or other foot problems. Poor circulation makes it harder for wounds to heal and increases the risk of infection.
Diabetic foot ulcers are a common complication of diabetic neuropathy and can lead to serious infections, hospitalization, and even amputation if not treated promptly and effectively. Preventive care, including regular foot exams, proper footwear, and good blood glucose control, is essential for people with diabetes to prevent or manage diabetic foot problems.
In medical terms, the foot is the part of the lower limb that is distal to the leg and below the ankle, extending from the tarsus to the toes. It is primarily responsible for supporting body weight and facilitating movement through push-off during walking or running. The foot is a complex structure made up of 26 bones, 33 joints, and numerous muscles, tendons, ligaments, and nerves that work together to provide stability, balance, and flexibility. It can be divided into three main parts: the hindfoot, which contains the talus and calcaneus (heel) bones; the midfoot, which includes the navicular, cuboid, and cuneiform bones; and the forefoot, which consists of the metatarsals and phalanges that form the toes.
A stomach ulcer, also known as a gastric ulcer, is a sore that forms in the lining of the stomach. It's caused by a breakdown in the mucous layer that protects the stomach from digestive juices, allowing acid to come into contact with the stomach lining and cause an ulcer. The most common causes are bacterial infection (usually by Helicobacter pylori) and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). Stomach ulcers may cause symptoms such as abdominal pain, bloating, heartburn, and nausea. If left untreated, they can lead to more serious complications like internal bleeding, perforation, or obstruction.
A duodenal ulcer is a type of peptic ulcer that develops in the lining of the first part of the small intestine, called the duodenum. It is characterized by a break in the mucosal layer of the duodinal wall, leading to tissue damage and inflammation. Duodenal ulcers are often caused by an imbalance between digestive acid and mucus production, which can be exacerbated by factors such as bacterial infection (commonly with Helicobacter pylori), nonsteroidal anti-inflammatory drug use, smoking, and stress. Symptoms may include gnawing or burning abdominal pain, often occurring a few hours after meals or during the night, bloating, nausea, vomiting, loss of appetite, and weight loss. Complications can be severe, including bleeding, perforation, and obstruction of the duodenum. Diagnosis typically involves endoscopy, and treatment may include antibiotics (if H. pylori infection is present), acid-suppressing medications, lifestyle modifications, and potentially surgery in severe cases.
A leg ulcer is a chronic wound that occurs on the lower extremities, typically on the inner or outer ankle. It's often caused by poor circulation, venous insufficiency, or diabetes. Leg ulcers can also result from injury, infection, or inflammatory diseases such as rheumatoid arthritis or lupus. These ulcers can be painful, and they may take a long time to heal, making them prone to infection. Proper diagnosis, treatment, and wound care are essential for healing leg ulcers and preventing complications.
Foot diseases refer to various medical conditions that affect the foot, including its structures such as the bones, joints, muscles, tendons, ligaments, blood vessels, and nerves. These conditions can cause symptoms like pain, swelling, numbness, difficulty walking, and skin changes. Examples of foot diseases include:
1. Plantar fasciitis: inflammation of the band of tissue that connects the heel bone to the toes.
2. Bunions: a bony bump that forms on the joint at the base of the big toe.
3. Hammertoe: a deformity in which the toe is bent at the middle joint, resembling a hammer.
4. Diabetic foot: a group of conditions that can occur in people with diabetes, including nerve damage, poor circulation, and increased risk of infection.
5. Athlete's foot: a fungal infection that affects the skin between the toes and on the soles of the feet.
6. Ingrown toenails: a condition where the corner or side of a toenail grows into the flesh of the toe.
7. Gout: a type of arthritis that causes sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, often starting with the big toe.
8. Foot ulcers: open sores or wounds that can occur on the feet, especially in people with diabetes or poor circulation.
9. Morton's neuroma: a thickening of the tissue around a nerve between the toes, causing pain and numbness.
10. Osteoarthritis: wear and tear of the joints, leading to pain, stiffness, and reduced mobility.
Foot diseases can affect people of all ages and backgrounds, and some may be prevented or managed with proper foot care, hygiene, and appropriate medical treatment.
A peptic ulcer is a sore or erosion in the lining of your stomach and the first part of your small intestine (duodenum). The most common causes of peptic ulcers are bacterial infection and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, or naproxen.
The symptoms of a peptic ulcer include abdominal pain, often in the upper middle part of your abdomen, which can be dull, sharp, or burning and may come and go for several days or weeks. Other symptoms can include bloating, burping, heartburn, nausea, vomiting, loss of appetite, and weight loss. Severe ulcers can cause bleeding in the digestive tract, which can lead to anemia, black stools, or vomit that looks like coffee grounds.
If left untreated, peptic ulcers can result in serious complications such as perforation (a hole through the wall of the stomach or duodenum), obstruction (blockage of the digestive tract), and bleeding. Treatment for peptic ulcers typically involves medications to reduce acid production, neutralize stomach acid, and kill the bacteria causing the infection. In severe cases, surgery may be required.
Amputation is defined as the surgical removal of all or part of a limb or extremity such as an arm, leg, foot, hand, toe, or finger. This procedure is typically performed to remove damaged or dead tissue due to various reasons like severe injury, infection, tumors, or chronic conditions that impair circulation, such as diabetes or peripheral arterial disease. The goal of amputation is to alleviate pain, prevent further complications, and improve the patient's quality of life. Following the surgery, patients may require rehabilitation and prosthetic devices to help them adapt to their new physical condition.
A pressure ulcer, also known as a pressure injury or bedsore, is defined by the National Pressure Injury Advisory Panel (NPIAP) as "localized damage to the skin and/or underlying soft tissue usually over a bony prominence or related to a medical or other device." The damage can be caused by intense and/or prolonged pressure or shear forces, or a combination of both. Pressure ulcers are staged based on their severity, ranging from an initial reddening of the skin (Stage 1) to full-thickness tissue loss that extends down to muscle and bone (Stage 4). Unstageable pressure ulcers are those in which the base of the wound is covered by yellow, tan, green or brown tissue and the extent of tissue damage is not visible. Suspected deep tissue injury (Suspected DTI) describes intact skin or non-blanchable redness of a localized area usually over a bony prominence due to pressure and/or shear. The area may be preceded by tissue that is painful, firm, mushy, boggy, warmer or cooler as compared to adjacent tissue.
A skin ulcer is a defined as a loss of continuity or disruption of the skin surface, often accompanied by inflammation and/or infection. These lesions can result from various causes including pressure, venous or arterial insufficiency, diabetes, and chronic dermatological conditions. Skin ulcers are typically characterized by their appearance, depth, location, and underlying cause. Common types of skin ulcers include pressure ulcers (also known as bedsores), venous leg ulcers, arterial ulcers, and diabetic foot ulcers. Proper evaluation, wound care, management of underlying conditions, and prevention strategies are crucial in the treatment of skin ulcers to promote healing and prevent complications.
Wound healing is a complex and dynamic process that occurs after tissue injury, aiming to restore the integrity and functionality of the damaged tissue. It involves a series of overlapping phases: hemostasis, inflammation, proliferation, and remodeling.
1. Hemostasis: This initial phase begins immediately after injury and involves the activation of the coagulation cascade to form a clot, which stabilizes the wound and prevents excessive blood loss.
2. Inflammation: Activated inflammatory cells, such as neutrophils and monocytes/macrophages, infiltrate the wound site to eliminate pathogens, remove debris, and release growth factors that promote healing. This phase typically lasts for 2-5 days post-injury.
3. Proliferation: In this phase, various cell types, including fibroblasts, endothelial cells, and keratinocytes, proliferate and migrate to the wound site to synthesize extracellular matrix (ECM) components, form new blood vessels (angiogenesis), and re-epithelialize the wounded area. This phase can last up to several weeks depending on the size and severity of the wound.
4. Remodeling: The final phase of wound healing involves the maturation and realignment of collagen fibers, leading to the restoration of tensile strength in the healed tissue. This process can continue for months to years after injury, although the tissue may never fully regain its original structure and function.
It is important to note that wound healing can be compromised by several factors, including age, nutrition, comorbidities (e.g., diabetes, vascular disease), and infection, which can result in delayed healing or non-healing chronic wounds.
Skin care, in a medical context, refers to the practice of maintaining healthy skin through various hygienic, cosmetic, and therapeutic measures. This can include:
1. Cleansing: Using appropriate cleansers to remove dirt, sweat, and other impurities without stripping the skin of its natural oils.
2. Moisturizing: Applying creams or lotions to keep the skin hydrated and prevent dryness.
3. Sun Protection: Using sunscreens, hats, and protective clothing to shield the skin from harmful ultraviolet (UV) rays which can cause sunburn, premature aging, and skin cancer.
4. Skin Care Products: Using over-the-counter or prescription products to manage specific skin conditions like acne, eczema, psoriasis, or rosacea.
5. Regular Check-ups: Regularly examining the skin for any changes, growths, or abnormalities that may indicate a skin condition or disease.
6. Lifestyle Factors: Maintaining a healthy lifestyle, including a balanced diet, regular exercise, adequate sleep, and avoiding habits like smoking and excessive alcohol consumption, which can negatively impact skin health.
It's important to note that while some general skincare advice applies to most people, individual skincare needs can vary greatly depending on factors like age, skin type (oily, dry, combination, sensitive), and specific skin conditions or concerns. Therefore, it's often beneficial to seek personalized advice from a dermatologist or other healthcare provider.
Diabetic neuropathies refer to a group of nerve disorders that are caused by diabetes. High blood sugar levels can injure nerves throughout the body, but diabetic neuropathies most commonly affect the nerves in the legs and feet.
There are four main types of diabetic neuropathies:
1. Peripheral neuropathy: This is the most common type of diabetic neuropathy. It affects the nerves in the legs and feet, causing symptoms such as numbness, tingling, burning, or shooting pain.
2. Autonomic neuropathy: This type of neuropathy affects the autonomic nerves, which control involuntary functions such as heart rate, blood pressure, digestion, and bladder function. Symptoms may include dizziness, fainting, digestive problems, sexual dysfunction, and difficulty regulating body temperature.
3. Proximal neuropathy: Also known as diabetic amyotrophy, this type of neuropathy affects the nerves in the hips, thighs, or buttocks, causing weakness, pain, and difficulty walking.
4. Focal neuropathy: This type of neuropathy affects a single nerve or group of nerves, causing symptoms such as weakness, numbness, or pain in the affected area. Focal neuropathies can occur anywhere in the body, but they are most common in the head, torso, and legs.
The risk of developing diabetic neuropathies increases with the duration of diabetes and poor blood sugar control. Other factors that may contribute to the development of diabetic neuropathies include genetics, age, smoking, and alcohol consumption.
Neurogenic arthropathy is a joint disease that occurs as a result of nerve damage or dysfunction. Also known as Charcot joint, this condition is characterized by joint destruction and deformity due to the loss of sensation and proprioception, which normally help protect the joint from excessive stress and injury.
Neurogenic arthropathy often affects people with diabetes, syphilis, leprosy, spinal cord injuries, or other conditions that damage nerves. The damage impairs the ability to feel pain, temperature, and position, making it difficult for individuals to notice or respond to joint injuries. Over time, this can lead to joint degeneration, fractures, dislocations, and severe deformities if left untreated.
Treatment typically involves managing the underlying nerve condition, immobilizing the affected joint with a brace or cast, and in some cases, surgical intervention to repair or replace damaged joints. Regular exercise, physical therapy, and maintaining a healthy lifestyle can also help manage symptoms and prevent further complications.
Acquired foot deformities refer to structural abnormalities of the foot that develop after birth, as opposed to congenital foot deformities which are present at birth. These deformities can result from various factors such as trauma, injury, infection, neurological conditions, or complications from a medical condition like diabetes or arthritis.
Examples of acquired foot deformities include:
1. Hammertoe - A deformity where the toe bends downward at the middle joint, resembling a hammer.
2. Claw toe - A more severe form of hammertoe where the toe also curls under, forming a claw-like shape.
3. Mallet toe - A condition where the end joint of a toe is bent downward, causing it to resemble a mallet.
4. Bunions - A bony bump that forms on the inside of the foot at the big toe joint, often causing pain and difficulty wearing shoes.
5. Tailor's bunion (bunionette) - A similar condition to a bunion, but it occurs on the outside of the foot near the little toe joint.
6. Charcot foot - A severe deformity that can occur in people with diabetes or other neurological conditions, characterized by the collapse and dislocation of joints in the foot.
7. Cavus foot - A condition where the arch of the foot is excessively high, causing instability and increasing the risk of ankle injuries.
8. Flatfoot (pes planus) - A deformity where the arch of the foot collapses, leading to pain and difficulty walking.
9. Pronation deformities - Abnormal rotation or tilting of the foot, often causing instability and increasing the risk of injury.
Treatment for acquired foot deformities varies depending on the severity and underlying cause but may include orthotics, physical therapy, medication, or surgery.
I'm sorry for any confusion, but "shoes" are not a medical term. Shoes are items of footwear intended to protect and comfort the feet. They typically have a durable sole that provides protection from sharp objects, hot surfaces, and the effects of moisture. The upper part of a shoe can be made from various materials such as leather, plastic, or textiles, and is designed to provide coverage and support for the foot.
If you have any questions related to medical terminology or health-related topics, I'd be happy to help!
Peptic ulcer hemorrhage is a medical condition characterized by bleeding in the gastrointestinal tract due to a peptic ulcer. Peptic ulcers are open sores that develop on the lining of the stomach, lower esophagus, or small intestine. They are usually caused by infection with the bacterium Helicobacter pylori or long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs).
When a peptic ulcer bleeds, it can cause symptoms such as vomiting blood or passing black, tarry stools. In severe cases, the bleeding can lead to shock, which is a life-threatening condition characterized by a rapid heartbeat, low blood pressure, and confusion. Peptic ulcer hemorrhage is a serious medical emergency that requires immediate treatment. Treatment may include medications to reduce stomach acid, antibiotics to eliminate H. pylori infection, and endoscopic procedures to stop the bleeding. In some cases, surgery may be necessary to repair the ulcer or remove damaged tissue.
A bandage is a medical dressing or covering applied to a wound, injury, or sore with the intention of promoting healing or preventing infection. Bandages can be made of a variety of materials such as gauze, cotton, elastic, or adhesive tape and come in different sizes and shapes to accommodate various body parts. They can also have additional features like fasteners, non-slip surfaces, or transparent windows for monitoring the condition of the wound.
Bandages serve several purposes, including:
1. Absorbing drainage or exudate from the wound
2. Protecting the wound from external contaminants and bacteria
3. Securing other medical devices such as catheters or splints in place
4. Reducing swelling or promoting immobilization of the affected area
5. Providing compression to control bleeding or prevent fluid accumulation
6. Relieving pain by reducing pressure on sensitive nerves or structures.
Proper application and care of bandages are essential for effective wound healing and prevention of complications such as infection or delayed recovery.
Hyperbaric oxygenation is a medical treatment in which a patient breathes pure oxygen in a pressurized chamber, typically at greater than one atmosphere absolute (ATA). This process results in increased levels of oxygen being dissolved in the blood and delivered to body tissues, thereby promoting healing, reducing inflammation, and combating infection. Hyperbaric oxygen therapy is used to treat various medical conditions, including carbon monoxide poisoning, decompression sickness, gangrene, and wounds that are slow to heal due to diabetes or radiation injury.
Foot injuries refer to any damage or trauma caused to the various structures of the foot, including the bones, muscles, tendons, ligaments, blood vessels, and nerves. These injuries can result from various causes such as accidents, sports activities, falls, or repetitive stress. Common types of foot injuries include fractures, sprains, strains, contusions, dislocations, and overuse injuries like plantar fasciitis or Achilles tendonitis. Symptoms may vary depending on the type and severity of the injury but often include pain, swelling, bruising, difficulty walking, and reduced range of motion. Proper diagnosis and treatment are crucial to ensure optimal healing and prevent long-term complications.
Debridement is a medical procedure that involves the removal of dead, damaged, or infected tissue to improve the healing process or prevent further infection. This can be done through various methods such as surgical debridement (removal of tissue using scalpel or scissors), mechanical debridement (use of wound irrigation or high-pressure water jet), autolytic debridement (using the body's own enzymes to break down and reabsorb dead tissue), and enzymatic debridement (application of topical enzymes to dissolve necrotic tissue). The goal of debridement is to promote healthy tissue growth, reduce the risk of infection, and improve overall wound healing.
Foot deformities refer to abnormal changes in the structure and/or alignment of the bones, joints, muscles, ligaments, or tendons in the foot, leading to a deviation from the normal shape and function of the foot. These deformities can occur in various parts of the foot, such as the toes, arch, heel, or ankle, and can result in pain, difficulty walking, and reduced mobility. Some common examples of foot deformities include:
1. Hammertoes: A deformity where the toe bends downward at the middle joint, resembling a hammer.
2. Mallet toes: A condition where the end joint of the toe is bent downward, creating a mallet-like shape.
3. Claw toes: A combination of both hammertoes and mallet toes, causing all three joints in the toe to bend abnormally.
4. Bunions: A bony bump that forms on the inside of the foot at the base of the big toe, caused by the misalignment of the big toe joint.
5. Tailor's bunion (bunionette): A similar condition to a bunion but occurring on the outside of the foot, at the base of the little toe.
6. Flat feet (pes planus): A condition where the arch of the foot collapses, causing the entire sole of the foot to come into contact with the ground when standing or walking.
7. High arches (pes cavus): An excessively high arch that doesn't provide enough shock absorption and can lead to pain and instability.
8. Cavus foot: A condition characterized by a very high arch and tight heel cord, often leading to an imbalance in the foot structure and increased risk of ankle injuries.
9. Haglund's deformity: A bony enlargement on the back of the heel, which can cause pain and irritation when wearing shoes.
10. Charcot foot: A severe deformity that occurs due to nerve damage in the foot, leading to weakened bones, joint dislocations, and foot collapse.
Foot deformities can be congenital (present at birth) or acquired (develop later in life) due to various factors such as injury, illness, poor footwear, or abnormal biomechanics. Proper diagnosis, treatment, and management are essential for maintaining foot health and preventing further complications.
Peptic ulcer perforation is a serious and sightful gastrointestinal complication characterized by the penetration or erosion of an acid-peptic ulcer through the full thickness of the stomach or duodenal wall, resulting in spillage of gastric or duodenal contents into the peritoneal cavity. This leads to chemical irritation and/or bacterial infection of the abdominal cavity, causing symptoms such as sudden severe abdominal pain, tenderness, rigidity, and potentially life-threatening sepsis if not promptly diagnosed and treated with surgical intervention, antibiotics, and supportive care.
'Foot bones,' also known as the tarsal and metatarsal bones, are the 26 bones that make up the foot in humans. The foot is divided into three parts: the hindfoot, midfoot, and forefoot.
The hindfoot contains two bones: the talus, which connects to the leg bone (tibia), and the calcaneus (heel bone). These bones form the ankle joint and heel.
The midfoot is made up of five irregularly shaped bones called the navicular, cuboid, and three cuneiform bones. These bones help form the arch of the foot and connect the hindfoot to the forefoot.
The forefoot contains the metatarsals (five long bones) and the phalanges (14 small bones). The metatarsals connect the midfoot to the toes, while the phalanges make up the toes themselves.
These bones work together to provide stability, support, and movement for the foot, allowing us to walk, run, and jump.
Osteomyelitis is a medical condition characterized by an infection that involves the bone or the bone marrow. It can occur as a result of a variety of factors, including bacterial or fungal infections that spread to the bone from another part of the body, or direct infection of the bone through trauma or surgery.
The symptoms of osteomyelitis may include pain and tenderness in the affected area, fever, chills, fatigue, and difficulty moving the affected limb. In some cases, there may also be redness, swelling, and drainage from the infected area. The diagnosis of osteomyelitis typically involves imaging tests such as X-rays, CT scans, or MRI scans, as well as blood tests and cultures to identify the underlying cause of the infection.
Treatment for osteomyelitis usually involves a combination of antibiotics or antifungal medications to eliminate the infection, as well as pain management and possibly surgical debridement to remove infected tissue. In severe cases, hospitalization may be necessary to monitor and manage the condition.
Artificial Skin is a synthetic substitute or equivalent that is used to replace, support, or enhance the function of damaged or absent skin. It can be made from various materials such as biopolymers, composites, or biosynthetic materials. The main purpose of artificial skin is to provide a temporary or permanent covering for wounds, burns, or ulcers that cannot be healed with conventional treatments. Additionally, it may serve as a platform for the delivery of medications or as a matrix for the growth of cells and tissues during skin grafting procedures. Artificial skin must possess properties such as biocompatibility, durability, flexibility, and permeability to air and water vapor in order to promote optimal healing and minimize scarring.
Buruli ulcer is a neglected tropical disease caused by the bacterium Mycobacterium ulcerans. It mainly affects the skin and occasionally the bones and joints. The infection typically begins with a painless nodule or papule that may progress to a large, painful ulcer with undermined edges if left untreated. In severe cases, it can lead to permanent disfigurement and disability. Buruli ulcer is primarily found in rural areas of West and Central Africa, but also occurs in other parts of the world including Australia, Asia, and South America. It is transmitted through contact with contaminated water or soil, although the exact mode of transmission is not fully understood. Early diagnosis and treatment with antibiotics can cure the disease and prevent complications.
A wound infection is defined as the invasion and multiplication of microorganisms in a part of the body tissue, which has been damaged by a cut, blow, or other trauma, leading to inflammation, purulent discharge, and sometimes systemic toxicity. The symptoms may include redness, swelling, pain, warmth, and fever. Treatment typically involves the use of antibiotics and proper wound care. It's important to note that not all wounds will become infected, but those that are contaminated with bacteria, dirt, or other foreign substances, or those in which the skin's natural barrier has been significantly compromised, are at a higher risk for infection.
"Foot joints" is a general term that refers to the various articulations or connections between the bones in the foot. There are several joints in the foot, including:
1. The ankle joint (tibiotalar joint): This is the joint between the tibia and fibula bones of the lower leg and the talus bone of the foot.
2. The subtalar joint (talocalcaneal joint): This is the joint between the talus bone and the calcaneus (heel) bone.
3. The calcaneocuboid joint: This is the joint between the calcaneus bone and the cuboid bone, which is one of the bones in the midfoot.
4. The tarsometatarsal joints (Lisfranc joint): These are the joints that connect the tarsal bones in the midfoot to the metatarsal bones in the forefoot.
5. The metatarsophalangeal joints: These are the joints between the metatarsal bones and the phalanges (toes) in the forefoot.
6. The interphalangeal joints: These are the joints between the phalanges within each toe.
Each of these foot joints plays a specific role in supporting the foot, absorbing shock, and allowing for movement and flexibility during walking and other activities.
Congenital foot deformities refer to abnormal structural changes in the foot that are present at birth. These deformities can vary from mild to severe and may affect the shape, position, or function of one or both feet. Common examples include clubfoot (talipes equinovarus), congenital vertical talus, and cavus foot. Congenital foot deformities can be caused by genetic factors, environmental influences during fetal development, or a combination of both. Treatment options may include stretching, casting, surgery, or a combination of these approaches, depending on the severity and type of the deformity.
Podiatry is the branch of medicine that deals with the diagnosis, prevention, and treatment of disorders of the foot, ankle, and lower extremities. Podiatrists are healthcare professionals who specialize in this field, also known as doctors of podiatric medicine (DPM). They receive specialized medical education and training to provide comprehensive care for various conditions such as bunions, hammertoes, heel pain, nerve damage, diabetic foot problems, and sports injuries among others. Treatment options may include medication, physical therapy, orthotics, or surgery.
Granulation tissue is the pinkish, bumpy material that forms on the surface of a healing wound. It's composed of tiny blood vessels (capillaries), white blood cells, and fibroblasts - cells that produce collagen, which is a protein that helps to strengthen and support the tissue.
Granulation tissue plays a crucial role in the wound healing process by filling in the wound space, contracting the wound, and providing a foundation for the growth of new skin cells (epithelialization). It's typically formed within 3-5 days after an injury and continues to develop until the wound is fully healed.
It's important to note that while granulation tissue is a normal part of the healing process, excessive or overgrowth of granulation tissue can lead to complications such as delayed healing, infection, or the formation of hypertrophic scars or keloids. In these cases, medical intervention may be necessary to manage the excess tissue and promote proper healing.
I'm sorry for any confusion, but "honey" is not typically considered a medical term. It is a natural sweet substance produced by honeybees from the nectar of flowers. Honey is composed primarily of fructose and glucose, with small amounts of other sugars, water, proteins, amino acids, vitamins, minerals, enzymes, and various organic compounds.
While honey does have some potential health benefits, such as its antimicrobial properties and its use in wound healing, it is not a medical treatment or intervention. If you have any questions about the medicinal uses of honey or its role in health, I would recommend consulting with a healthcare professional.
Hydrocolloid bandages are a type of dressing used in wound care. They consist of an outer waterproof layer and an inner hydrophilic layer made of materials such as gelatin, pectin, or carboxymethylcellulose. When the bandage comes into contact with moisture from the wound, it forms a gel that helps to maintain a moist environment, which can promote healing.
Hydrocolloid bandages are useful for managing a variety of wound types, including partial-thickness burns, pressure ulcers, and diabetic foot ulcers. They can help to protect the wound from external contaminants, reduce pain and discomfort, and provide sustained release of medications such as analgesics or antibiotics.
One advantage of hydrocolloid bandages is that they can be left in place for several days at a time, which can reduce the frequency of dressing changes and minimize trauma to the wound bed. However, it's important to monitor the wound regularly to ensure that it is healing properly and to check for signs of infection or other complications.
Negative-Pressure Wound Therapy (NPWT) is a medical treatment used to promote wound healing and prevent infection in acute or chronic wounds. It involves the application of controlled sub-atmospheric pressure to the surface of the wound, usually through the use of a vacuum-assisted device.
The negative pressure helps to remove excess fluid and infectious materials from the wound, while also promoting the growth of new tissue by increasing blood flow and stimulating cell proliferation. NPWT can be used in various types of wounds, including diabetic foot ulcers, pressure ulcers, surgical wounds, and traumatic injuries.
The therapy is typically administered through a sealed dressing that covers the wound and is connected to a vacuum pump. The negative pressure is applied continuously or intermittently, depending on the specific needs of the patient and the type of wound being treated. NPWT has been shown to be effective in reducing wound size, promoting healing, and improving overall clinical outcomes in many patients with complex wounds.
Silver compounds refer to chemical substances that combine silver (Ag) with one or more other elements. In the medical context, silver compounds are known for their antimicrobial properties and have been used in various medical applications such as wound dressings, creams, and coatings on medical devices.
Some examples of silver compounds include:
* Silver sulfadiazine (AgSD): a common topical antibiotic used to prevent and treat bacterial infections in burn wounds.
* Silver nitrate (AgNO3): a strong antiseptic used to treat wounds, skin infections, and eye conditions such as neonatal conjunctivitis.
* Silver chloride (AgCl): a compound used in some wound dressings for its antimicrobial properties.
* Silver proteinate: a silver compound that is often used in dietary supplements and claimed to have immune-boosting and anti-inflammatory effects, although its efficacy is not well established.
It's important to note that while silver compounds can be effective antimicrobial agents, they can also have potential side effects such as skin irritation, discoloration, and in some cases, argyria (a bluish-gray discoloration of the skin caused by excessive accumulation of silver). Therefore, they should be used under the guidance of a healthcare professional.
Diabetes complications refer to a range of health issues that can develop as a result of poorly managed diabetes over time. These complications can affect various parts of the body and can be classified into two main categories: macrovascular and microvascular.
Macrovascular complications include:
* Cardiovascular disease (CVD): People with diabetes are at an increased risk of developing CVD, including coronary artery disease, peripheral artery disease, and stroke.
* Peripheral arterial disease (PAD): This condition affects the blood vessels that supply oxygen and nutrients to the limbs, particularly the legs. PAD can cause pain, numbness, or weakness in the legs and may increase the risk of amputation.
Microvascular complications include:
* Diabetic neuropathy: This is a type of nerve damage that can occur due to prolonged high blood sugar levels. It commonly affects the feet and legs, causing symptoms such as numbness, tingling, or pain.
* Diabetic retinopathy: This condition affects the blood vessels in the eye and can cause vision loss or blindness if left untreated.
* Diabetic nephropathy: This is a type of kidney damage that can occur due to diabetes. It can lead to kidney failure if not managed properly.
Other complications of diabetes include:
* Increased risk of infections, particularly skin and urinary tract infections.
* Slow healing of wounds, which can increase the risk of infection and amputation.
* Gum disease and other oral health problems.
* Hearing impairment.
* Sexual dysfunction.
Preventing or managing diabetes complications involves maintaining good blood sugar control, regular monitoring of blood glucose levels, following a healthy lifestyle, and receiving routine medical care.
Orthopedic equipment refers to devices or appliances used in the practice of orthopedics, which is a branch of medicine focused on the correction, support, and prevention of disorders, injuries, or deformities of the skeletal system, including bones, joints, ligaments, tendons, and muscles. These devices can be categorized into various types based on their function and application:
1. Mobility aids: Equipment that helps individuals with impaired mobility to move around more easily, such as walkers, crutches, canes, wheelchairs, and scooters.
2. Immobilization devices: Used to restrict movement of a specific body part to promote healing, prevent further injury, or provide support during rehabilitation, including casts, braces, splints, slings, and collars.
3. Prosthetics: Artificial limbs that replace missing body parts due to amputation, illness, or congenital defects, enabling individuals to perform daily activities and maintain independence.
4. Orthotics: Custom-made or off-the-shelf devices worn inside shoes or on the body to correct foot alignment issues, provide arch support, or alleviate pain in the lower extremities.
5. Rehabilitation equipment: Devices used during physical therapy sessions to improve strength, flexibility, balance, and coordination, such as resistance bands, exercise balls, balance boards, and weight training machines.
6. Surgical instruments: Specialized tools used by orthopedic surgeons during operations to repair fractures, replace joints, or correct deformities, including saws, drills, retractors, and screwdrivers.
7. Diagnostic equipment: Imaging devices that help healthcare professionals assess musculoskeletal conditions, such as X-ray machines, CT scanners, MRI machines, and ultrasound systems.
These various types of orthopedic equipment play a crucial role in the diagnosis, treatment, rehabilitation, and management of orthopedic disorders and injuries, enhancing patients' quality of life and functional abilities.
A varicose ulcer is a type of chronic wound that typically occurs on the lower leg, often as a result of poor circulation and venous insufficiency. These ulcers form when there is increased pressure in the veins, leading to damage and leakage of fluids into the surrounding tissues. Over time, this can cause the skin to break down and form an open sore or ulcer.
Varicose ulcers are often associated with varicose veins, which are swollen and twisted veins that are visible just beneath the surface of the skin. These veins have weakened walls and valves, which can lead to the pooling of blood and fluid in the lower legs. This increased pressure can cause damage to the surrounding tissues, leading to the formation of an ulcer.
Varicose ulcers are typically slow to heal and may require extensive treatment, including compression therapy, wound care, and sometimes surgery. Risk factors for developing varicose ulcers include obesity, smoking, sedentary lifestyle, and a history of deep vein thrombosis or other circulatory problems.
In medical terms, pressure is defined as the force applied per unit area on an object or body surface. It is often measured in millimeters of mercury (mmHg) in clinical settings. For example, blood pressure is the force exerted by circulating blood on the walls of the arteries and is recorded as two numbers: systolic pressure (when the heart beats and pushes blood out) and diastolic pressure (when the heart rests between beats).
Pressure can also refer to the pressure exerted on a wound or incision to help control bleeding, or the pressure inside the skull or spinal canal. High or low pressure in different body systems can indicate various medical conditions and require appropriate treatment.
Gangrene is a serious and potentially life-threatening condition that occurs when there is a loss of blood flow to a specific area of the body, resulting in tissue death. It can be caused by various factors such as bacterial infections, trauma, diabetes, vascular diseases, and smoking. The affected tissues may become discolored, swollen, and emit a foul odor due to the accumulation of bacteria and toxins.
Gangrene can be classified into two main types: dry gangrene and wet (or moist) gangrene. Dry gangrene develops slowly and is often associated with peripheral arterial disease, which reduces blood flow to the extremities. The affected area turns black and shriveled as it dries out. Wet gangrene, on the other hand, progresses rapidly due to bacterial infections that cause tissue breakdown and pus formation. This type of gangrene can spread quickly throughout the body, leading to severe complications such as sepsis and organ failure if left untreated.
Treatment for gangrene typically involves surgical removal of the dead tissue (debridement), antibiotics to control infections, and sometimes revascularization procedures to restore blood flow to the affected area. In severe cases where the infection has spread or the damage is irreversible, amputation of the affected limb may be necessary to prevent further complications and save the patient's life.
A nursing assessment is the process of collecting and analyzing data about a patient's health status, including their physical, psychological, social, cultural, and emotional needs. This information is used to identify actual or potential health problems, develop a plan of care, and evaluate the effectiveness of interventions. Nursing assessments may include observing and documenting the patient's vital signs, appearance, behavior, mobility, nutrition, elimination, comfort level, cognitive status, and emotional well-being. They are typically conducted upon admission to a healthcare facility, during transitions of care, and on a regular basis throughout the course of treatment to ensure that the patient's needs are being met and that any changes in their condition are promptly identified and addressed.
Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.
In the context of medical terminology, "vacuum" is not typically used as a standalone term with a specific medical definition. However, it can be used in certain medical procedures or conditions in relation to creating a partial vacuum or absence of pressure. For example:
1. In surgical procedures, such as a vacuum-assisted closure, a vacuum is applied to help promote wound healing by removing fluids and infectious materials from the wound site.
2. In some cases, a therapeutic vacuum may be used to treat soft tissue injuries or conditions like lymphedema, where controlled negative pressure is applied to improve circulation, reduce swelling, and promote healing.
3. A rare medical condition called "spontaneous intracranial hypotension" can occur when there is a leak in the dura mater (the protective membrane surrounding the brain and spinal cord), causing cerebrospinal fluid to escape and creating a negative pressure or vacuum-like effect within the skull, which may result in headaches, neck pain, or other neurological symptoms.
In general, "vacuum" is not a commonly used medical term with a specific definition but can be found in relation to certain procedures or conditions where a partial vacuum or absence of pressure is involved.
Hand, foot, and mouth disease (HFMD) is a mild, contagious viral infection common in infants and children but can sometimes occur in adults. The disease is often caused by coxsackievirus A16 or enterovirus 71.
The name "hand, foot and mouth" comes from the fact that blister-like sores usually appear in the mouth (and occasionally on the buttocks and legs) along with a rash on the hands and feet. The disease is not related to foot-and-mouth disease (also called hoof-and-mouth disease), which affects cattle, sheep, and swine.
HFMD is spread through close personal contact, such as hugging and kissing, or through the air when an infected person coughs or sneezes. It can also be spread by touching objects and surfaces that have the virus on them and then touching the face. People with HFMD are most contagious during the first week of their illness but can still be contagious for weeks after symptoms go away.
There is no specific treatment for HFMD, and it usually resolves on its own within 7-10 days. However, over-the-counter pain relievers and fever reducers may help alleviate symptoms. It's important to encourage good hygiene practices, such as handwashing and covering the mouth and nose when coughing or sneezing, to prevent the spread of HFMD.
Diabetic angiopathies refer to a group of vascular complications that occur due to diabetes mellitus. Prolonged exposure to high blood sugar levels can damage the blood vessels, leading to various types of angiopathies such as:
1. Diabetic retinopathy: This is a condition where the small blood vessels in the retina get damaged due to diabetes, leading to vision loss or blindness if left untreated.
2. Diabetic nephropathy: In this condition, the kidneys' glomeruli (the filtering units) become damaged due to diabetes, leading to protein leakage and eventually kidney failure if not managed properly.
3. Diabetic neuropathy: This is a type of nerve damage caused by diabetes that can affect various parts of the body, including the legs, feet, and hands, causing numbness, tingling, or pain.
4. Diabetic cardiomyopathy: This is a condition where the heart muscle becomes damaged due to diabetes, leading to heart failure.
5. Diabetic peripheral arterial disease (PAD): In this condition, the blood vessels that supply the legs and feet become narrowed or blocked due to diabetes, leading to pain, cramping, or even gangrene in severe cases.
Overall, diabetic angiopathies are serious complications of diabetes that can significantly impact a person's quality of life and overall health. Therefore, it is crucial for individuals with diabetes to manage their blood sugar levels effectively and undergo regular check-ups to detect any early signs of these complications.
Foot dermatoses refer to various skin conditions that affect the feet. These can include inflammatory conditions like eczema and psoriasis, infectious diseases such as athlete's foot (tinea pedis), fungal infections, bacterial infections, viral infections (like plantar warts caused by HPV), and autoimmune blistering disorders. Additionally, contact dermatitis from irritants or allergens can also affect the feet. Proper diagnosis is essential to determine the best course of treatment for each specific condition.
Medicare Part A is the hospital insurance component of Medicare, which is a federal health insurance program in the United States. Specifically, Part A helps cover the costs associated with inpatient care in hospitals, skilled nursing facilities, and some types of home health care. This can include things like semi-private rooms, meals, nursing services, and any other necessary hospital services and supplies.
Part A coverage also extends to hospice care for individuals who are terminally ill and have a life expectancy of six months or less. In this case, Part A helps cover the costs associated with hospice care, including pain management, symptom control, and emotional and spiritual support for both the patient and their family.
It's important to note that Medicare Part A is not completely free, as most people do not pay a monthly premium for this coverage. However, there are deductibles and coinsurance costs associated with using Part A services, which can vary depending on the specific service being provided.
Medical professionals define "flatfoot" or "pes planus" as a postural deformity in which the arch of the foot collapses, leading to the entire sole of the foot coming into complete or near-complete contact with the ground. This condition can be classified as flexible (the arch reappears when the foot is not bearing weight) or rigid (the arch does not reappear). Flatfoot can result from various factors such as genetics, injury, aging, or certain medical conditions like rheumatoid arthritis and cerebral palsy. In some cases, flatfoot may not cause any symptoms or problems; however, in other instances, it can lead to pain, discomfort, or difficulty walking. Treatment options for flatfoot depend on the severity of the condition and associated symptoms and may include physical therapy, orthotics, bracing, or surgery.
Prospective studies, also known as longitudinal studies, are a type of cohort study in which data is collected forward in time, following a group of individuals who share a common characteristic or exposure over a period of time. The researchers clearly define the study population and exposure of interest at the beginning of the study and follow up with the participants to determine the outcomes that develop over time. This type of study design allows for the investigation of causal relationships between exposures and outcomes, as well as the identification of risk factors and the estimation of disease incidence rates. Prospective studies are particularly useful in epidemiology and medical research when studying diseases with long latency periods or rare outcomes.
"Forms and Records Control" is not a recognized medical term or concept. However, in a broader healthcare context, "Records Control" typically refers to the systematic management and maintenance of patient records to ensure their accuracy, confidentiality, and accessibility. This includes establishing policies and procedures for creating, storing, retrieving, using, and disposing of records in compliance with applicable laws and regulations.
"Forms," on the other hand, are standardized documents used in healthcare settings to collect and record patient information. "Forms Control" may refer to the management and tracking of these forms to ensure they are up-to-date, compliant with relevant regulations, and accessible to authorized personnel. This can include developing and implementing processes for creating, revising, approving, distributing, and retiring healthcare forms.
In summary, "Forms and Records Control" in a healthcare context could be interpreted as the combined management of standardized forms used to collect patient information and the systematic maintenance of those records to ensure accuracy, confidentiality, and compliance with applicable laws and regulations.
Silver Sulfadiazine is a topical antimicrobial cream, primarily used for the prevention and treatment of burn wounds' infections. It has broad-spectrum activity against various bacteria, including gram-positive and gram-negative organisms, as well as some fungi. The cream creates a physical barrier that helps minimize bacterial growth and contains silver, which has antimicrobial properties. Silver Sulfadiazine is often used in combination with other burn wound care treatments to optimize healing and reduce the risk of complications such as sepsis.
The medical definition of Silver Sulfadiazine can be stated as:
A topical antimicrobial agent, chemically described as silver(I) 1-(4-amino-2-sulfonylphenyl)-2-(N-pyrimidin-2-ylsulfamoyl)ethanone dihydrate. It is primarily used for the prevention and treatment of infections associated with burn wounds due to its broad-spectrum antibacterial and antifungal properties. The compound is available as a white cream, which forms a protective layer on the wound, releasing silver ions that inhibit bacterial growth and promote healing.
Diabetes Mellitus, Type 2 is a metabolic disorder characterized by high blood glucose (or sugar) levels resulting from the body's inability to produce sufficient amounts of insulin or effectively use the insulin it produces. This form of diabetes usually develops gradually over several years and is often associated with older age, obesity, physical inactivity, family history of diabetes, and certain ethnicities.
In Type 2 diabetes, the body's cells become resistant to insulin, meaning they don't respond properly to the hormone. As a result, the pancreas produces more insulin to help glucose enter the cells. Over time, the pancreas can't keep up with the increased demand, leading to high blood glucose levels and diabetes.
Type 2 diabetes is managed through lifestyle modifications such as weight loss, regular exercise, and a healthy diet. Medications, including insulin therapy, may also be necessary to control blood glucose levels and prevent long-term complications associated with the disease, such as heart disease, nerve damage, kidney damage, and vision loss.
Anti-ulcer agents are a class of medications that are used to treat and prevent ulcers in the gastrointestinal tract. These medications work by reducing the production of stomach acid, neutralizing stomach acid, or protecting the lining of the stomach and duodenum from damage caused by stomach acid.
There are several types of anti-ulcer agents, including:
1. Proton pump inhibitors (PPIs): These medications block the action of proton pumps in the stomach, which are responsible for producing stomach acid. PPIs include drugs such as omeprazole, lansoprazole, and pantoprazole.
2. H-2 receptor antagonists: These medications block the action of histamine on the H-2 receptors in the stomach, reducing the production of stomach acid. Examples include ranitidine, famotidine, and cimetidine.
3. Antacids: These medications neutralize stomach acid and provide quick relief from symptoms such as heartburn and indigestion. Common antacids include calcium carbonate, magnesium hydroxide, and aluminum hydroxide.
4. Protective agents: These medications form a barrier between the stomach lining and stomach acid, protecting the lining from damage. Examples include sucralfate and misoprostol.
Anti-ulcer agents are used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It is important to take these medications as directed by a healthcare provider, as they can have side effects and interactions with other medications.
Clubfoot, also known as talipes equinovarus, is a congenital foot deformity where the foot is twisted inward and downward. The affected foot appears to be turned inward and downward, resembling a club or a bowling pin. This condition usually affects one foot but can occur in both feet as well.
The cause of clubfoot is not fully understood, but it is believed to be a combination of genetic and environmental factors. Clubfoot is often diagnosed at birth or during routine prenatal ultrasound exams. Treatment for clubfoot typically involves nonsurgical methods such as stretching, casting, and bracing to gradually correct the position of the foot over time. In some cases, surgery may be required to release tight tendons and realign the bones in the foot and ankle.
If left untreated, clubfoot can lead to significant mobility issues and difficulty walking or participating in activities. However, with early intervention and consistent treatment, most children with clubfoot are able to lead active and normal lives.
A physical examination is a methodical and systematic process of evaluating a patient's overall health status. It involves inspecting, palpating, percussing, and auscultating different parts of the body to detect any abnormalities or medical conditions. The primary purpose of a physical examination is to gather information about the patient's health, identify potential health risks, diagnose medical conditions, and develop an appropriate plan for prevention, treatment, or further evaluation.
During a physical examination, a healthcare provider may assess various aspects of a patient's health, including their vital signs (such as blood pressure, heart rate, temperature, and respiratory rate), height, weight, body mass index (BMI), and overall appearance. They may also examine different organ systems, such as the cardiovascular, respiratory, gastrointestinal, neurological, musculoskeletal, and genitourinary systems, to identify any signs of disease or abnormalities.
Physical examinations are an essential part of preventive healthcare and are typically performed during routine check-ups, annual physicals, and when patients present with symptoms or concerns about their health. The specific components of a physical examination may vary depending on the patient's age, sex, medical history, and presenting symptoms.
Helicobacter pylori (H. pylori) is a gram-negative, microaerophilic bacterium that colonizes the stomach of approximately 50% of the global population. It is closely associated with gastritis and peptic ulcer disease, and is implicated in the pathogenesis of gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. H. pylori infection is usually acquired in childhood and can persist for life if not treated. The bacterium's spiral shape and flagella allow it to penetrate the mucus layer and adhere to the gastric epithelium, where it releases virulence factors that cause inflammation and tissue damage. Diagnosis of H. pylori infection can be made through various tests, including urea breath test, stool antigen test, or histological examination of a gastric biopsy. Treatment typically involves a combination of antibiotics and proton pump inhibitors to eradicate the bacteria and promote healing of the stomach lining.
Topical administration refers to a route of administering a medication or treatment directly to a specific area of the body, such as the skin, mucous membranes, or eyes. This method allows the drug to be applied directly to the site where it is needed, which can increase its effectiveness and reduce potential side effects compared to systemic administration (taking the medication by mouth or injecting it into a vein or muscle).
Topical medications come in various forms, including creams, ointments, gels, lotions, solutions, sprays, and patches. They may be used to treat localized conditions such as skin infections, rashes, inflammation, or pain, or to deliver medication to the eyes or mucous membranes for local or systemic effects.
When applying topical medications, it is important to follow the instructions carefully to ensure proper absorption and avoid irritation or other adverse reactions. This may include cleaning the area before application, covering the treated area with a dressing, or avoiding exposure to sunlight or water after application, depending on the specific medication and its intended use.
Ischemia is the medical term used to describe a lack of blood flow to a part of the body, often due to blocked or narrowed blood vessels. This can lead to a shortage of oxygen and nutrients in the tissues, which can cause them to become damaged or die. Ischemia can affect many different parts of the body, including the heart, brain, legs, and intestines. Symptoms of ischemia depend on the location and severity of the blockage, but they may include pain, cramping, numbness, weakness, or coldness in the affected area. In severe cases, ischemia can lead to tissue death (gangrene) or organ failure. Treatment for ischemia typically involves addressing the underlying cause of the blocked blood flow, such as through medication, surgery, or lifestyle changes.
Follow-up studies are a type of longitudinal research that involve repeated observations or measurements of the same variables over a period of time, in order to understand their long-term effects or outcomes. In medical context, follow-up studies are often used to evaluate the safety and efficacy of medical treatments, interventions, or procedures.
In a typical follow-up study, a group of individuals (called a cohort) who have received a particular treatment or intervention are identified and then followed over time through periodic assessments or data collection. The data collected may include information on clinical outcomes, adverse events, changes in symptoms or functional status, and other relevant measures.
The results of follow-up studies can provide important insights into the long-term benefits and risks of medical interventions, as well as help to identify factors that may influence treatment effectiveness or patient outcomes. However, it is important to note that follow-up studies can be subject to various biases and limitations, such as loss to follow-up, recall bias, and changes in clinical practice over time, which must be carefully considered when interpreting the results.
Foot orthoses, also known as orthotic devices or simply orthotics, are custom-made or prefabricated shoe inserts that are designed to support, align, correct, or accommodate various foot and ankle deformities or biomechanical issues. They can be made of different materials such as plastic, rubber, leather, or foam and are inserted into the shoes to provide extra cushioning, arch support, or realignment of the foot structure.
Custom-made foot orthoses are created based on a mold or a digital scan of the individual's foot, taking into account their specific needs and medical condition. These devices are typically prescribed by healthcare professionals such as podiatrists, orthopedic surgeons, or physical therapists to treat various conditions such as plantar fasciitis, flat feet, high arches, bunions, diabetic foot ulcers, or arthritis.
Foot orthoses can help improve foot function, reduce pain and discomfort, prevent further deformities, and enhance overall mobility and quality of life.
Helicobacter infections are caused by the bacterium Helicobacter pylori (H. pylori), which colonizes the stomach lining and is associated with various gastrointestinal diseases. The infection can lead to chronic active gastritis, peptic ulcers, gastric mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric cancer.
The spiral-shaped H. pylori bacteria are able to survive in the harsh acidic environment of the stomach by producing urease, an enzyme that neutralizes gastric acid in their immediate vicinity. This allows them to adhere to and colonize the epithelial lining of the stomach, where they can cause inflammation (gastritis) and disrupt the normal functioning of the stomach.
Transmission of H. pylori typically occurs through oral-oral or fecal-oral routes, and infection is more common in developing countries and in populations with lower socioeconomic status. The diagnosis of Helicobacter infections can be confirmed through various tests, including urea breath tests, stool antigen tests, or gastric biopsy with histology and culture. Treatment usually involves a combination of antibiotics and proton pump inhibitors to eradicate the bacteria and reduce stomach acidity.
Diabetes Mellitus, Type 1 is a chronic autoimmune disease characterized by the destruction of insulin-producing beta cells in the pancreas, leading to an absolute deficiency of insulin. This results in an inability to regulate blood glucose levels, causing hyperglycemia (high blood sugar). Type 1 diabetes typically presents in childhood or early adulthood, although it can develop at any age. It is usually managed with regular insulin injections or the use of an insulin pump, along with monitoring of blood glucose levels and adjustments to diet and physical activity. Uncontrolled type 1 diabetes can lead to serious complications such as kidney damage, nerve damage, blindness, and cardiovascular disease.
Exudates and transudates are two types of bodily fluids that can accumulate in various body cavities or tissues as a result of injury, inflammation, or other medical conditions. Here are the medical definitions:
1. Exudates: These are fluids that accumulate due to an active inflammatory process. Exudates contain high levels of protein, white blood cells (such as neutrophils and macrophages), and sometimes other cells like red blood cells or cellular debris. They can be yellow, green, or brown in color and may have a foul odor due to the presence of dead cells and bacteria. Exudates are often seen in conditions such as abscesses, pneumonia, pleurisy, or wound infections.
Examples of exudative fluids include pus, purulent discharge, or inflammatory effusions.
2. Transudates: These are fluids that accumulate due to increased hydrostatic pressure or decreased oncotic pressure within the blood vessels. Transudates contain low levels of protein and cells compared to exudates. They are typically clear and pale yellow in color, with no odor. Transudates can be found in conditions such as congestive heart failure, liver cirrhosis, or nephrotic syndrome.
Examples of transudative fluids include ascites, pleural effusions, or pericardial effusions.
It is essential to differentiate between exudates and transudates because their underlying causes and treatment approaches may differ significantly. Medical professionals often use various tests, such as fluid analysis, to determine whether a fluid sample is an exudate or transudate.
In medical terms, the leg refers to the lower portion of the human body that extends from the knee down to the foot. It includes the thigh (femur), lower leg (tibia and fibula), foot, and ankle. The leg is primarily responsible for supporting the body's weight and enabling movements such as standing, walking, running, and jumping.
The leg contains several important structures, including bones, muscles, tendons, ligaments, blood vessels, nerves, and joints. These structures work together to provide stability, support, and mobility to the lower extremity. Common medical conditions that can affect the leg include fractures, sprains, strains, infections, peripheral artery disease, and neurological disorders.
Diabetes Mellitus is a chronic metabolic disorder characterized by elevated levels of glucose in the blood (hyperglycemia) due to absolute or relative deficiency in insulin secretion and/or insulin action. There are two main types: Type 1 diabetes, which results from the autoimmune destruction of pancreatic beta cells leading to insulin deficiency, and Type 2 diabetes, which is associated with insulin resistance and relative insulin deficiency.
Type 1 diabetes typically presents in childhood or young adulthood, while Type 2 diabetes tends to occur later in life, often in association with obesity and physical inactivity. Both types of diabetes can lead to long-term complications such as damage to the eyes, kidneys, nerves, and cardiovascular system if left untreated or not well controlled.
The diagnosis of diabetes is usually made based on fasting plasma glucose levels, oral glucose tolerance tests, or hemoglobin A1c (HbA1c) levels. Treatment typically involves lifestyle modifications such as diet and exercise, along with medications to lower blood glucose levels and manage associated conditions.
The tarsal bones are a group of seven articulating bones in the foot that make up the posterior portion of the foot, located between the talus bone of the leg and the metatarsal bones of the forefoot. They play a crucial role in supporting the body's weight and facilitating movement.
There are three categories of tarsal bones:
1. Proximal row: This includes the talus, calcaneus (heel bone), and navicular bones. The talus articulates with the tibia and fibula to form the ankle joint, while the calcaneus is the largest tarsal bone and forms the heel. The navicular bone is located between the talus and the cuneiform bones.
2. Intermediate row: This includes the cuboid bone, which is located laterally (on the outside) to the navicular bone and articulates with the calcaneus, fourth and fifth metatarsals, and the cuneiform bones.
3. Distal row: This includes three cuneiform bones - the medial, intermediate, and lateral cuneiforms - which are located between the navicular bone proximally and the first, second, and third metatarsal bones distally. The medial cuneiform is the largest of the three and articulates with the navicular bone, first metatarsal, and the intermediate cuneiform. The intermediate cuneiform articulates with the medial and lateral cuneiforms and the second metatarsal. The lateral cuneiform articulates with the intermediate cuneiform, cuboid, and fourth metatarsal.
Together, these bones form a complex network of joints that allow for movement and stability in the foot. Injuries or disorders affecting the tarsal bones can result in pain, stiffness, and difficulty walking.
In medical terms, the skin is the largest organ of the human body. It consists of two main layers: the epidermis (outer layer) and dermis (inner layer), as well as accessory structures like hair follicles, sweat glands, and oil glands. The skin plays a crucial role in protecting us from external factors such as bacteria, viruses, and environmental hazards, while also regulating body temperature and enabling the sense of touch.
I'm sorry for any confusion, but "France" is not a medical term or concept. France is the largest country in Western Europe and the third-largest in Europe after Russia and Ukraine. It has been a major player in world affairs for centuries, with a significant cultural and artistic influence. If you have any questions about medical terms or concepts, I would be happy to help answer those for you.
"Mycobacterium ulcerans" is a slow-growing mycobacterium that is the causative agent of a chronic infection known as Buruli ulcer. This bacterium is naturally found in aquatic environments and can infect humans through minor traumas or wounds on the skin. The infection typically begins as a painless nodule or papule, which may progress to form necrotic ulcers if left untreated. The bacteria produce a unique toxin called mycolactone, which is responsible for the extensive tissue damage and destruction observed in Buruli ulcers.
Angiogenesis inducing agents are substances or drugs that stimulate the growth of new blood vessels, a process known as angiogenesis. This process is essential for the growth and development of tissues and organs in the body, including wound healing and the formation of blood vessels in the placenta during pregnancy. However, abnormal angiogenesis can also contribute to various diseases, such as cancer, diabetic retinopathy, and age-related macular degeneration.
Angiogenesis inducing agents are being studied for their potential therapeutic benefits in a variety of medical conditions. For example, they may be used to promote wound healing or tissue repair after injury or surgery. In cancer treatment, angiogenesis inhibitors are often used to block the growth of new blood vessels and prevent tumors from growing and spreading. However, angiogenesis inducing agents can have the opposite effect and may potentially be used to enhance the delivery of drugs to tumors or improve the effectiveness of other cancer treatments.
Examples of angiogenesis inducing agents include certain growth factors, such as vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and platelet-derived growth factor (PDGF). These substances can be administered as drugs to stimulate angiogenesis in specific contexts. Other substances, such as hypoxia-inducible factors (HIFs) and prostaglandins, can also induce angiogenesis under certain conditions.
Medical Definition:
"Risk factors" are any attribute, characteristic or exposure of an individual that increases the likelihood of developing a disease or injury. They can be divided into modifiable and non-modifiable risk factors. Modifiable risk factors are those that can be changed through lifestyle choices or medical treatment, while non-modifiable risk factors are inherent traits such as age, gender, or genetic predisposition. Examples of modifiable risk factors include smoking, alcohol consumption, physical inactivity, and unhealthy diet, while non-modifiable risk factors include age, sex, and family history. It is important to note that having a risk factor does not guarantee that a person will develop the disease, but rather indicates an increased susceptibility.
Peripheral Arterial Disease (PAD) is a medical condition characterized by the narrowing or blockage of arteries that supply blood to the extremities, most commonly the legs. This results in reduced blood flow, leading to symptoms such as leg pain, cramping, numbness, or weakness during physical activity, and in severe cases, tissue damage or gangrene. PAD is often indicative of widespread atherosclerosis, which is the hardening and narrowing of arteries due to the buildup of fatty deposits called plaques. It's important to note that early detection and management can help prevent serious complications.
I'm sorry for any confusion, but "Washington" is not a medical term. It is a place name, referring to the U.S. state of Washington or the city of Washington, D.C., the capital of the United States. If you have any questions about medical terms or concepts, I would be happy to help answer those for you!
Diabetic foot ulcer
Arterial insufficiency ulcer
Marjolin's ulcer
Tropical ulcer
Ulcer (dermatology)
Venous ulcer
Hereditary sensory and autonomic neuropathy type I
Diabetic foot infection
Immersion foot syndromes
Peter DeMarco
Magainin
27th (Inniskilling) Regiment of Foot
Tom Brumley
David G. Armstrong
Lee Rogers (podiatrist)
Arabic language influence on the Spanish language
Mouth ulcer
Maggot therapy
Epidermal growth factor
Extracorporeal shockwave therapy
Lawrence B. Harkless
Hydrogel dressing
Diabetic foot
Hydrocolloid dressing
Alginate dressing
Total contact casting
Deaths in January 2008
Carotenoid complex
Nepidermin
Medical error
Ultrasonography of chronic venous insufficiency of the legs
Diabetic shoe
Diabetic foot ulcer - Wikipedia
foot ulcer Clinical Research Trials | CenterWatch
Can Zoo Poo Help Manage Diabetic Foot Ulcers?
Diabetic Foot Ulcers: Practice Essentials, Pathophysiology, Etiology
Patients With Infected Diabetic Foot Ulcers Need Quick Referral
Novel Diabetic Foot Ulcer Cream Shows Promise in Phase 3 Trial
Bioengineered skin in diabetic foot ulcers
Do you have a foot ulcer? | Clinical Research Trial Listing ( Diabetic Foot Ulcers ) ( TX138790 )
New Research Suggests Promise in Preventing Amputation from Diabetic Foot Ulcers | Johns Hopkins Medicine
Best Treatment For Diabetic Foot Ulcer | Healthy Feet Store
Placental Allografts for Diabetic Foot Ulcers: Interview with Tim Wright, CEO of MiMedx
Diabetic Foot Ulcer CEU | Wild Iris Medical Education
Diabetic Foot Ulcer: Care Instructions | Kaiser Permanente
Spectral MD Initiates EU Diabetic Foot Ulcer Clinical Study in Ireland | Newswire
Finding hot spots on their soles helps diabetics avoid dangerous foot ulcers - NWTN Today
Foot ulcers: perception of patients with Type 2 diabetes
Intralesional application of epidermal growth factor in limbthreatening ischemic diabetic foot ulcers
Extended Extracorporeal Shockwave Therapy for Wound Care in Chronic Diabetic Foot Ulcers | WoundSource
Could Nebivolol be an Alternative Drug for the Treatment of Diabetic Foot Ulcers? in: Journal of the American Podiatric Medical...
Diabetic Foot Ulcer Illustration by Adam Questell | Medical Illustration & Animation
Preliminary Evaluation of a Cycling Cleat Designed for Diabetic Foot Ulcers in: Journal of the American Podiatric Medical...
Effects of adding adjunctive hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers: a protocol for a...
Low vitamin D linked with increased diabetic foot ulcers - Desang Diabetes Services
Chinese medicine and diabetic foot ulcers - iPodiatry
Meeting report: Go beyond: A multidisciplinary approach for the management of diabetic foot ulcers - Wounds International
Three-pronged approach stops foot ulcers
Wagner Scale For Diabetic Foot Ulcers - Spagati.Com
Foot Ulcer Sensors Market Share & Growth Analysis Report
Tongue ulcer: How to identify, symptoms, treatment, and more
Amputation28
- [ 3 ] Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States, with approximately 5% of diabetics developing foot ulcers each year and 1% requiring amputation. (medscape.com)
- Fifty-two (17.4%) of patients had amputation of some part of the foot during follow-up, 18 (6.0%) underwent peripheral revascularization, and 10 (3.3%) underwent both procedures. (medscape.com)
- The median time to healing of the index ulcer was 4.5 months, while median time to amputation, if this occurred, was 2.0 months, and for revascularization, it was 3.0 months. (medscape.com)
- Kaplan-Meier curve showing association of the area deprivation index (ADI) with lower extremity reamputation after minor foot amputation in patients with diabetes. (hopkinsmedicine.org)
- Diabetes is the leading cause of non-traumatic lower extremity amputations in the United States, and approximately 14 to 24 percent of patients with diabetes who develop a foot ulcer have an amputation. (healthyfeetstore.com)
- Foot ulcers in patients with diabetes should be treated for several reasons such as, reducing the risk of infection and amputation, improving function and quality of life, and reducing health care costs. (healthyfeetstore.com)
- Discuss amputation as it relates to diabetic foot ulcers. (wildirismedicaleducation.com)
- Treating a simple diabetic foot ulcer can cost $8,000, double that for an infected one and even more for an amputation. (nwtntoday.com)
- On the other hand, it's very hard to take your temperature when you don't think there's a problem there," cautions Massa, 53, who has used the thermometer since Armstrong helped him narrowly avoid amputation when the joints in his foot disintegrated. (nwtntoday.com)
- In the past decade, the incidence of diabetes mellitus has increased exorbitantly around the world and foot ulcer has become the most serious and costly complication, leading to possible amputation or even death. (scielo.org.co)
- One of the chronic complications of diabetes mellitus type 2 (DM2) is diabetic foot (DF) 3 , which can result in amputation if it progresses to an ulcer. (scielo.org.co)
- 2 It is critical to treat DFUs effectively and in a timely fashion because ulcers may progress to the point of requiring an amputation. (woundsource.com)
- Preliminary studies have indicated that systemic treatment of diabetic foot ulcer patients with hyperbaric oxygen therapy have beneficial effects on wound healing, risk of amputation, glycaemic control, atherosclerosis, inflammatory markers and other clinical and laboratory parameters. (bmj.com)
- About 15 percent of people with diabetes get foot ulcers at one point in their lifetime, and about 15 percent of ulcers develop a bone infection, or osteomyelitis, and about 15 percent of ulcers result in amputation,' he says. (dermatologytimes.com)
- The 5-year mortality rate for individuals with a diabetic foot ulcer is approximately 30%, exceeding 70% for those with a major amputation. (diabeticfootonline.com)
- People who are Black, Hispanic, or Native American and people with low socioeconomic status have higher rates of diabetic foot ulcer and subsequent amputation compared with White people. (diabeticfootonline.com)
- Conclusions and Relevance Diabetic foot ulcers affect approximately 18.6 million people worldwide each year and are associated with increased rates of amputation and death. (diabeticfootonline.com)
- Dedicated to amputation prevention, wound healing, diabetic foot, biotechnology and the intersection between medical devices and consumer electronics. (diabeticfootonline.com)
- Predictors of healing, ulcer recurrence and persistence, amputation and mortality in type 2 diabetic patients with diabetic foot : a 10-year retrospective cohort study / C. Gazzaruso, P. Gallotti, A. Pujia, T. Montalcini, A. Giustina, A. Coppola. (unimi.it)
- Foot ulcers are common and can be hard to treat, but failure to heal them carries high risk for amputation and mortality. (ulcertalk.com)
- A transmetatarsal amputation from the 2 nd to the 5 th toes on the right foot was previously carried out in a different hospital due to inadequate healing of a DFU. (faoj.org)
- The physical examination showed a lateral subluxation of the first metatarsophalangeal joint, an ulcer on the amputation stump, with granulation on the base and no inflammatory signs, proliferative signs, dermatosclerosis or hyperpigmentation of the skin edges (Figure 1). (faoj.org)
- There are some ways to prevent amputation such as only removing the infected skin from the ulcer or decreasing pressure around the ulcer. (feetfirst-footcare.com)
- Diabetic foot ulcers can get so bad that amputation is nessesary and they are almost always the result of a simple cut, scrape, or puncture that a non-diabetic person would hardly give a second thought about. (bestshoesfordiabetics.com)
- Diabetic foot ulcers (DFUs) are a common complication of diabetes and can lead to severe disability and even amputation . (bvsalud.org)
- However, it is unclear whether minor amputation negatively affects HRQoL compared with conservative treatment in patients with diabetic foot ulcers. (lu.se)
- Methods: In the cohort of the multicenter, prospective, observational Eurodiale study, we determined difference in change of HRQoL measured by EQ-5D between patients with a diabetic foot ulcers that healed after conservative treatment (n = 676) and after minor amputation (n = 145). (lu.se)
- Conclusions: Minor amputation was not associated with a negative impact on HRQoL in patients with a diabetic foot ulcers. (lu.se)
Pressure Ulcers1
- The Optional Pressure Ulcer Foot is an ideal training device to be used alongside the GERi and KERi simulators to reinforce the locations pressure ulcers are likely to appear in. (medicalsuppliesgh.com)
Management of diabetic foot ulcers3
- This study reports the use of STIMULAN as a carrier material for vancomycin and gentamicin in the management of diabetic foot ulcers complicated by osteomyelitis. (biocomposites.com)
- The study was carried out in a 'real world' population and thus EDX110 is indicated in the management of diabetic foot ulcers, even when mildly infected, and as long as the ankle-brachial pressure index is above 0.5," Dr. Edmonds said. (medscape.com)
- A diabetic foot ulcer is very problematic and difficult to treat, that's is why its management involves a multidisciplinary approach like primary care surgeons, nurses, podiatrists, diabetologists, and vascular surgeons, as well as all healthcare providers involved in the prevention or management of diabetic foot ulcers. (zorghealth.com)
DFUs10
- Bioengineered skin (BS) has been shown to play an important role in the treatment of diabetic foot ulcers (DFUs). (nih.gov)
- Conn Hastings, Medgadget: Please give us an overview of diabetic foot ulcers (DFUs) and their consequences for patients. (medgadget.com)
- DFUs develop from a combination of factors such as lack of feeling in the foot, poor circulation, irritation (such as friction or pressure), and duration of diabetes. (medgadget.com)
- Chronic diabetic foot ulcers (DFUs) affect approximately 13% of the U.S. population. (woundsource.com)
- 1 DFUs are defined by the authors of this article as, "nonhealing ulcers of the foot lasting more than 3 months' duration in patients with diabetes. (woundsource.com)
- Given the prevalence of diabetic foot disease and the challenging nature of healing DFUs, researchers are investigating alternate treatment methods. (woundsource.com)
- A recent study has found that low serum levels of vitamin D were significantly associated with a higher prevalence of diabetic foot ulcers (DFUs) in elderly patients with diabetes. (desang.net)
- Pathogenesis: DFUs frequently caused by repetitive injury to an insensate or vascular compromised foot. (hopkinsguides.com)
- Sustained hyperglycemia derives in numerous complications, mostly caused by macro and microangiopathy [1], of special importance are Diabetic Foot Ulcers (DFUs). (faoj.org)
- Moreover, the addition of different factors such as the of loss of skin integrity, existence of foot deformities (Hallux Valgus, Charcot's arthropathy, etc.), and peripheral vascular disease ultimately lead to the formation of DFUs [4]. (faoj.org)
Infection21
- Risk factors implicated in the development of diabetic foot ulcers are infection, older age, diabetic neuropathy, peripheral vascular disease, cigarette smoking, poor glycemic control, previous foot ulcerations or amputations, and ischemia of small and large blood vessels. (wikipedia.org)
- Blisters and sores may appear on numb areas of the feet and legs, such as metatarsophalangeal joints and the heel region, as a result of pressure or injury which may go unnoticed and eventually become a portal of entry for bacteria and infection. (wikipedia.org)
- Diabetic foot ulcers can be staged using the Wound, Ischemia, and foot Infection (WIfI) threatened limb classification system. (medscape.com)
- Current standard clinical care for diabetic foot ulcer consists of debridement, off-loading, infection control, and maintaining a moist environment with dressings, Huang and colleagues explain. (medscape.com)
- For the analysis, the researchers performed a 12-month prospective observational assessment, via detailed review of case notes, of 250 patients with diabetes who had participated in the Concordance in Diabetic Foot Ulcer Infection (CODIFI) study and were still alive at the end of that, in May 2013. (medscape.com)
- Of those who develop a foot ulcer, six percent will be hospitalized due to infection or other ulcer-related complication. (healthyfeetstore.com)
- Vascular disease can complicate a foot ulcer, reducing the body's ability to heal and increasing the risk for an infection. (healthyfeetstore.com)
- We know that wounds and ulcers heal faster, with a lower risk of infection, if they are kept covered and moist. (healthyfeetstore.com)
- The ulcers often present with complications such as infection, which frequently result in hospitalization. (medgadget.com)
- If the infection is severe, then tissue in the foot can die. (kaiserpermanente.org)
- Worse, foot ulcers are so slow-healing and vulnerable to infection that they're to blame for most of the roughly 80,000 amputations of toes, feet and lower legs that diabetics undergo each year. (nwtntoday.com)
- Established treatments for foot ulcers, after treating infection and poor circulation, include off-loading, debridement and then moist wound healing. (dermatologytimes.com)
- Here, the amount of tissue loss, ischemia, and foot infection can be ordinally graded to help predict outcome and assist in communicating a plan of action. (diabeticfootonline.com)
- Vascular Guidelines.49 a Grading based on the Wound, Ischemia, and Foot Infection (WIfI) classification system. (diabeticfootonline.com)
- Classifying ulcers based on the degree of tissue loss, ischemia, and infection can help identify risk of limb-threatening disease. (diabeticfootonline.com)
- Surgical debridement, reducing pressure from weight bearing on the ulcer, and treating lower extremity ischemia and foot infection are first-line therapies for diabetic foot ulcers. (diabeticfootonline.com)
- Currently recommended treatments of wound dressings and foot infection control dont always achieve complete wound healing and are expensive for long term use, so this review added to understanding about better approaches. (ulcertalk.com)
- If not treated early enough, diabetic foot ulcers can lead to complications such as osteomyelitis (infection of the bone), gangrene (tissue death), and foot abnormalities. (healthviber.com)
- The critical factors that delay the healing of diabetic foot ulcers are ischemia and infection," Dr. Michael E. Edmonds from King's College Hospital in London told Reuters Health by email. (medscape.com)
- Nitric oxide (NO) plays a crucial role in maintaining the microvascular supply and infection control in the skin, and its absence in diabetes contributes to poor ulcer healing. (medscape.com)
- People with diabetes should regularly examine their feet for any skin abnormalities such as ulcers or signs of infection. (who.int)
Ischemia4
- Presence of limb ischemia, multiple foot ulcers, and a longer ulcer duration were most predictive of poor 12-month outcomes. (medscape.com)
- Diagnosing whether or not a diabetic foot ulcer is infected can be difficult, especially in the presence of limb ischemia or peripheral neuropathy, the researchers note, but it is generally agreed that this decision should be based on signs or symptoms of inflammation or purulence. (medscape.com)
- Narrowed arteries and reduced blood flow, which doctors call ischemia, cause ischemic ulcers. (medicalnewstoday.com)
- Diagnosing ischemic ulcers involves a physical exam to look for signs of ischemia, such as a lack of pulse or a bluish or pale appearance of the skin. (medicalnewstoday.com)
20232
- DALLAS, February 21, 2023 (Newswire.com) - Spectral MD Holdings, Ltd. (AIM: SMD), a predictive analytics company with proprietary AI algorithms and optical technology for faster and more accurate treatment decisions in wound care, announces the initiation of its EU clinical study to support the development and regulatory submission of its Diabetic Foot Ulcer (DFU) application for the Company's DeepView™ technology. (newswire.com)
- The global demand for Foot Ulcer Sensors Market is presumed to reach the market size of nearly USD 224.57 MN by 2030 from USD 160.23 MN in 2022 with a CAGR of 4.31% under the study period 2023 - 2030. (valuemarketresearch.com)
Sores7
- Mouth ulcers or canker sores that appear on the tongue usually clear up without treatment. (medicalnewstoday.com)
- Tongue ulcers are whiteish sores on the tongue. (medicalnewstoday.com)
- Also called canker sores, a 2019 article notes that these ulcers most often develop on the inside of the lips and cheeks. (medicalnewstoday.com)
- This can result in either the slow and gradual deformation of the foot as joints are realigned and some small bones are even cracked or it can result in sores developing on the skin of the foot. (bestshoesfordiabetics.com)
- The best ways to treat diabetic foot ulcers and sores is to prevent the pressure points and sores from happening in the first place. (bestshoesfordiabetics.com)
- Blisters and sores can develop when your foot presses against your shoe. (medlineplus.gov)
- Did (s)he have sores or ulcers anywhere on the body? (cdc.gov)
Heal13
- However, the number of amputations from chronic diabetic foot ulcers that do not heal is increasing, pointing to a need for better treatment options. (medscape.com)
- After a foot ulcer has formed, it will not heal as long as you keep putting weight on the area. (kaiserpermanente.org)
- Participant Paul Rau of Green Valley, Ariz., had a recurring ulcer on his left big toe for six years, a quarter-inch bone-deep hole that took weeks to heal each time. (nwtntoday.com)
- New York - Uniform treatment consisting of a three-pronged approach can help patients with foot ulcers heal more effectively and prevent chronic ulceration and the need for amputations, according to Peter Sheehan, M.D., director of the Diabetic Foot and Ankle Center for Joint Diseases, Orthopaedic Institute in New York, N.Y. (dermatologytimes.com)
- Tongue ulcers tend to heal on their own. (medicalnewstoday.com)
- Approximately 30% to 40% of diabetic foot ulcers heal at 12 weeks, and recurrence after healing is estimated to be 42% at 1 year and 65% at 5 years. (diabeticfootonline.com)
- This, in turn, can lead to the formation of painful ulcers that are slow to heal or may not heal at all. (medicalnewstoday.com)
- Skin grafts and tissue replacement products can help heal diabetic foot ulcers in some cases, and may also slightly reduce the numbers of future amputations. (ulcertalk.com)
- As a result, they may develop foot ulcerations that are painless and heal poorly. (healthviber.com)
- Ulcers may take even longer to heal if you don't control your blood sugar levels or if constant pressure is applied to the ulcer. (zorghealth.com)
- Most foot wounds that don't want to heal occur because the capillaries in that area of the foot are clogged or have shrunk. (bestshoesfordiabetics.com)
- As a result, your feet are more likely to become injured and may not heal well if they are injured. (medlineplus.gov)
- Shallow ulcers with scabs that then heal without scarring follow the formation of vesicles. (medscape.com)
Wounds7
- The study followed 277 patients with 621 diabetic foot wounds treated by the Johns Hopkins experts between 2012 and 2017. (hopkinsmedicine.org)
- The Johns Hopkins service, started in 2012 under the direction of vascular surgeon Christopher Abularrage , features vascular surgeons, a surgical podiatrist, an endocrinologist, an infectious diseases specialist, a certified wound nurse and a physician assistant working together to manage both inpatients and outpatients presenting with foot wounds. (hopkinsmedicine.org)
- Diabetic foot ulcers are complex, chronic wounds that are often disabling and greatly impact the morbidity and mortality of patients. (wildirismedicaleducation.com)
- USA: Acellular fish skin graft promotes wound healing in patients with diabetic foot ulcers , finds a recent study published in the journal Wounds . (ulcertalk.com)
- Due to this large patient population, diabetic wounds have become a growing problem and the treatment of diabetic foot ulcers creates a large financial burden in India annually. (ulcertalk.com)
- Usually this involves the prescription of antibiotics, medicinal and topical, as well as proper irrigation of diabetic wounds and general foot care. (bestshoesfordiabetics.com)
- People with diabetes have to be constantly checking their feet for foot wounds or potential problems. (bestshoesfordiabetics.com)
Debridement4
- 12%. They also had to have a Wagner grade 1 or 2 foot ulcer that was 1-25 cm 2 after debridement, had been treated with standard care, and was present for at least 4 weeks. (medscape.com)
- All 20 patients in the study had forefoot ulcers with underlying osteomyelitis and had failed to respond to a treatment protocol of wound debridement, systemic antibiotics and off-loading. (biocomposites.com)
- After debridement of the ulcer, preservation of the bony structure was achieved by covering it with a fillet flap. (faoj.org)
- The main treatments include wound debridement (removing dead skin and tissue), moist wound dressings, reducing weight on the ulcer (via orthotics or shoe changes), antibiotics to combat infections, and controlling blood sugar levels (poorly controlled blood sugar can impair wound healing). (healthviber.com)
Associated with diabetic foot ulcers2
- Equinus has been associated with diabetic foot ulcers, as it increases plantar pressures in the forefoot and midfoot. (medscape.com)
- They also may be risk factors for amputations associated with diabetic foot ulcers, according to a recent Johns Hopkins study. (hopkinsmedicine.org)
Amputations6
- Investigators, including several from the Multidisciplinary Diabetic Foot and Wound Service, reviewed Maryland Health Services Cost Review Commission database records of 7,415 patients with diabetes undergoing minor amputations (below the ankle) between 2012 and 2019. (hopkinsmedicine.org)
- Objective: The intralesional injection of recombinant human epidermal growth factor (EGF-IL), a new therapy, has been claimed to prevent major amputations in advanced diabetic foot lesions. (aott.org.tr)
- Conclusion: Our results prove that intralesional application of EGF can prevent amputations in advanced diabetic foot cases with an ischemic component. (aott.org.tr)
- These ulcers precede 80% of lower extremity amputations among people diagnosed with diabetes and are associated with an increased risk of death. (diabeticfootonline.com)
- Approximately 50% to 60% of ulcers become infected, and about 20% of moderate to severe infections lead to lower extremity amputations. (diabeticfootonline.com)
- Untreated foot ulcers are the most common reason for toe, foot, and leg amputations in people with diabetes. (medlineplus.gov)
Prevent diabetic foot ulcers1
- Taking good care of your feet can help prevent diabetic foot ulcers. (medlineplus.gov)
Ulceration5
- Observations Neurological, vascular, and biomechanical factors contribute to diabetic foot ulceration. (diabeticfootonline.com)
- Foot ulceration due to neuropathy is a serious cause of morbidity in diabetes. (diabetesfeetaustralia.org)
- Ulceration usually occurs at the part of the foot subjected to excessive mechanical pressure. (diabetesfeetaustralia.org)
- However there was no difference in pressure between the foot with previous ulceration and the contralateral foot (9.7 +/- 6.8 kg cm-2, 11.6 +/- 7.9 kg cm-2). (diabetesfeetaustralia.org)
- It is the foot affected by ulceration and neuropathy and/or peripheral arterial disease (a disorder of blood supply) of the foot in a patient with uncontrolled diabetes. (zorghealth.com)
Prevention3
- Describe the important components of off-loading in the prevention and treatment of diabetic foot ulcers. (wildirismedicaleducation.com)
- This blog discusses the prevention, diagnosis, and classification of diabetic foot ulcers. (vedelan.com)
- Aside from ulcer prevention a diabetic person needs to treat diabetic foot ulcers as part of a larger diabetic management program led by the patient's doctor. (bestshoesfordiabetics.com)
Tissue13
- Treatment of diabetic foot ulcers should include: blood sugar control, removal of dead tissue from the wound, wound dressings, and removing pressure from the wound through techniques such as total contact casting. (wikipedia.org)
- All patients harboring diabetic foot ulcers should be evaluated by a qualified vascular surgeon and podiatric surgeon who will consider débridement, reconstructive surgery on bony architecture, vascular reconstruction, and options for soft tissue coverage. (medscape.com)
- Non-enzymatic glycosylation of skin and connective tissue, along with decreased collagen production in people with diabetes, result in alterations in the biomechanics in the diabetic foot. (medscape.com)
- If the foot ulcer does not respond, growth factors, tissue-engineering products, hyperbaric oxygen, or negative pressure wound therapies may be used. (medscape.com)
- These issues have inspired a different approach in the form of a human tissue-derived off-the-shelf graft that can be applied to an ulcer. (medgadget.com)
- Your doctor may have removed the dead tissue and cleaned the ulcer. (kaiserpermanente.org)
- Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis. (ipodiatry.org)
- This review showed skin grafts or tissue replacement moderately increased the healing rate of the most amenable diabetic foot ulcers in people with diabetes that is, in those who had sufficient blood flow in their feet. (ulcertalk.com)
- Complete ulcer healing at 6 to 16 weeks was 423 per 1,000 people using skin grafts or tissue replacement, significantly more than the 273 per 1,000 achieved in standard care. (ulcertalk.com)
- They are openings in the skin of the foot that reveal the tissue underneath. (feetfirst-footcare.com)
- Foot ulcers are quite common in diabetes and are formed due to the breakdown of the skin's tissue, thus exposing the layers underneath. (vedelan.com)
- The most noticeable indication of a genuine foot ulcer is black tissue (called eschar) encompassing the ulcer. (vedelan.com)
- Incomplete or complete gangrene, which alludes to tissue death because of infections, can appear around the ulcer. (vedelan.com)
Diabetics7
- WASHINGTON (AP) - Diabetics, watch out: A hot spot on your foot can signal an ulcer is brewing, a wound that could cost your limb. (nwtntoday.com)
- Foot ulcers each year strike 600,000 U.S. diabetics, people slow to notice they even have a wound because diabetes has numbed their feet. (nwtntoday.com)
- Foot ulcers effect diabetics in high numbers. (feetfirst-footcare.com)
- All diabetics have the potential to develop foot ulcers. (feetfirst-footcare.com)
- Those diabetics that use insulin and also have another disease are usually at a higher risk of developing foot ulcers. (feetfirst-footcare.com)
- To ensure that the proper shoes are worn and that damage is limited or eliminated diabetics really should have their feet molded so that insoles can be created with the exact foot contours for the individual. (bestshoesfordiabetics.com)
- This sometimes means removing shoes every few hours and can even require some diabetics to have a loved one check their feet for them as it can be physically difficult for some patients. (bestshoesfordiabetics.com)
Lower extremity1
- Initial studies of electrotherapy seem promising, and topical application of the recombinant human growth factor becaplermin has been approved for use in patients with diabetic neuropathic ulcers of the lower extremity. (medscape.com)
Chronic4
- The findings of this study suggest that ON101, a macrophage regulator that behaves differently from moisture-retaining dressings, represents an active-healing alternative for home and primary care of patients with chronic [diabetic foot ulcers]," the researchers conclude. (medscape.com)
- The ulcers become chronic when they exhibit faulty healing,' says Dr. Sheehan. (dermatologytimes.com)
- An ischemic ulcer is a chronic wound that occurs due to a lack of blood supply in an area of the body, such as the legs. (medicalnewstoday.com)
- They are the most common type of chronic ulcer on the legs. (medicalnewstoday.com)
Dressings4
- Phages isolated from the feces could potentially be incorporated into dressings for ulcers, creating a novel treatment modality that is both effective and cost-saving. (medscape.com)
- ON101 (Fespixon, Oneness Biotech), a first-in-class, macrophage-regulating, wound-healing cream for diabetic foot ulcers has shown benefit over absorbent dressings in a phase 3 trial, with another trial ongoing. (medscape.com)
- Applying medication or dressings to the ulcer. (healthyfeetstore.com)
- These range from normal saline to advanced products, such as growth factors, ulcer dressings, and skin substitutes that have been shown to be highly effective in healing foot ulcers. (healthyfeetstore.com)
Recurrence4
- The analysis of almost 300 patients with infected diabetic foot ulcers also showed that, even if the ulcer healed, nearly 10% experienced a recurrence within 12 months and more than 25% of patients underwent some kind of procedure. (medscape.com)
- After 12 months of further follow-up, the index ulcer had healed in a total of 136 (45.5%) of the 299 patients, while 13 (9.6%) had a recurrence. (medscape.com)
- Analysis outcomes included complete wound closure, complications, ulcer recurrence and adverse severe events (ASEs). (nih.gov)
- We know that adults with diabetes who have had foot ulcers in the past have a really high rate of recurrence, and the only way to avoid that is to have regular foot exams, good glucose control, and learn new gait patterns to avoid pressure in the area of the previous ulcer," she explains. (hopkinsmedicine.org)
Patients27
- Oneness Biotech has also just started a second phase 3 trial in the United States, with a planned enrollment of 208 patients with diabetic foot ulcers, which will compare ON101 cream versus placebo cream, in addition to standard care, over 20 weeks. (medscape.com)
- Patients with an infected diabetic foot ulcer have a far worse prognosis than previously thought, with 15% of patients dying within a year, less than half of the ulcers healing in the same time period, and one in seven individuals having all or part of their foot amputated, results from a new UK study reveal. (medscape.com)
- Once we get patients into our clinic and treat them for their first diabetic foot ulcer, we follow them regularly, so if they start to develop another wound we can address it immediately," Hicks says. (hopkinsmedicine.org)
- Experts with the service use the latest technologies in evaluating patients' gait and in reconstructing the foot, he says. (hopkinsmedicine.org)
- A diabetic foot ulcer is an open sore or wound that most commonly occurs on the bottom of the foot in approximately 15 percent of patients with diabetes. (healthyfeetstore.com)
- People who use insulin are at a higher risk of developing a foot ulcer, as are patients with diabetes-related kidney, eye, and heart disease. (healthyfeetstore.com)
- Patients who have diabetes for many years can develop neuropathy, a reduced or complete lack of feeling in the feet due to nerve damage caused by elevated blood glucose levels over time. (healthyfeetstore.com)
- Diabetic foot ulcers are relatively common in patients with diabetes, presenting in as many as 15% of such patients. (medgadget.com)
- List the steps that comprise a foot assessment in patients with diabetes. (wildirismedicaleducation.com)
- Summarize the management program for patients with diabetic foot ulcers. (wildirismedicaleducation.com)
- Patients who develop a DFU are at higher risk of early death, heart attack, and fatal stroke than people with diabetes who do not develop diabetic foot ulcers. (wildirismedicaleducation.com)
- Using the thermometer reduced by nearly two-thirds the number of high-risk patients who got foot ulcers, Armstrong found in a study of 225 diabetic veterans, the third in a series of government-funded research to back the approach. (nwtntoday.com)
- Patients measure half a dozen spots on each foot. (nwtntoday.com)
- Patients are urged to wear proper-fitting shoes and check their feet daily for redness, bumps or other signs of trouble. (nwtntoday.com)
- In an NIH-funded study last year, Texas A&M College of Medicine researchers reported 30 percent of patients got ulcers even when using a mirror to check their soles, compared with 8.5 percent of thermometer users. (nwtntoday.com)
- To know the perception of diabetic patients attached to CESFAM BelarminaParedes, Futrono, Chile, regarding the occurrence of diabetic foot ulcers in 2015. (scielo.org.co)
- Four patients were evaluated for changes in blood flow perfusion rate, ulcer size, and an extensive immunohistochemical analysis. (woundsource.com)
- Vitamin D deficiency is common in elderly patients with diabetes, and this research - the first study to assess vitamin D levels in elderly patients hospitalized with a diabetic foot ulcer - found that, as average serum levels of vitamin D decreased, the severity of diabetic foot ulcers increased. (desang.net)
- Foot ulcers occur in patients with neuropathy. (dermatologytimes.com)
- Purpose: Predictors of outcome of diabetic foot ulcer (DFU) are important to improve the management of patients. (unimi.it)
- The therapeutic management in patients with advanced diabetic foot should be individualized based on patient characteristics. (faoj.org)
- A more generalized increase in pressure under the feet has also been shown to be a feature of many patients with diabetic neuropathy. (diabetesfeetaustralia.org)
- The maximum vertical foot bearing pressure was found to be higher in 11 diabetic patients with previously healed unilateral foot ulcers (10.6 +/- 5.9 kg cm-2) than in 11 diabetic patients who did not have such a history (4.2 +/- 1.3 kg cm-2). (diabetesfeetaustralia.org)
- Vertical foot bearing pressure was decreased by an average of 18% by wearing shoes padded with a Professional Protective Technology insole and the decrease was greater in patients with higher foot pressure. (diabetesfeetaustralia.org)
- Dr. Edmonds and colleagues assessed the safety and efficacy of EDX110 in the treatment of diabetic foot ulcers in their 12-week study of 147 patients. (medscape.com)
- In subgroup analysis, PAR was significantly greater with EDX110 than with best clinical practice among patients whose ulcers had been present for six or fewer months or were at least 1 cm2 at baseline, but not for those whose ulcers had been present for longer or were smaller. (medscape.com)
- Background: Health-related quality of life (HRQoL) is poor in patients with persistent diabetic foot ulcers and poor HRQoL predicts worse outcomes in these patients. (lu.se)
Neuropathic ulcers1
- There are Neuropathic ulcers, Ischemic ulcers and a combination of both. (feetfirst-footcare.com)
Ischemic ulcers9
- This article explores ischemic ulcers and provides an overview of their symptoms, causes, and treatments. (medicalnewstoday.com)
- Where do ischemic ulcers occur? (medicalnewstoday.com)
- Ischemic ulcers most commonly affect the lower limbs, particularly the feet and toes. (medicalnewstoday.com)
- The lower legs are also prone to swelling and pressure, which can further compromise blood flow and contribute to the development of ischemic ulcers. (medicalnewstoday.com)
- While ischemic ulcers are primarily a skin condition, they can also affect internal organs, such as the colon. (medicalnewstoday.com)
- Venous and arterial ulcers are both types of ischemic ulcers, which describes ulcers that occur due to a lack of blood flow in general. (medicalnewstoday.com)
- In contrast, ischemic ulcers are often symmetrical in shape with defined borders. (medicalnewstoday.com)
- What causes ischemic ulcers? (medicalnewstoday.com)
- By ulcer type , the neuro-ischemic ulcers segment is expected to remain the largest segment, registering a significant CAGR of 14.4% in terms of value over the forecast period. (financedigest.com)
Treatment18
- In a striking convergence of veterinary biology and medical science, researchers from the University of Sheffield have unveiled findings that could potentially advance the treatment of diabetic foot ulcers, a condition affecting an estimated 18.6 million people worldwide. (medscape.com)
- The primary goal in the treatment of foot ulcers is to obtain healing as soon as possible. (healthyfeetstore.com)
- Tightly controlling blood glucose is of the utmost importance during the treatment of a diabetic foot ulcer. (healthyfeetstore.com)
- MiMedx , a medtech company based in Georgia, has developed EpiFix , an off-the-shelf allograft system for the treatment of diabetic foot ulcers. (medgadget.com)
- This includes coverage by the largest U.S. commercial payor as a proven and medically necessary option in the treatment of diabetic foot ulcers. (medgadget.com)
- Always get early treatment for foot problems. (kaiserpermanente.org)
- There isn't any other treatment one knows about to (help) at that point before there's an ulcer. (nwtntoday.com)
- 2 However, the current case series does not provide adequate data to support the conclusion that ESWT is an effective treatment for the diabetic foot. (woundsource.com)
- Could Nebivolol be an Alternative Drug for the Treatment of Diabetic Foot Ulcers? (japmaonline.org)
- Minimally invasive treatment of a diabetic foot ulcer. (medillsb.com)
- We plan to include all relevant randomised clinical trials assessing the effects of hyperbaric oxygen therapy in the treatment of diabetic foot ulcer versus any control group with any intervention defined as standard wound care or similar, together with sham interventions. (bmj.com)
- Medical treatment for tongue ulcers generally focuses on easing the symptoms while identifying and treating any underlying conditions responsible for the ulcers. (medicalnewstoday.com)
- For example, if a person has diabetes, their treatment plan may include strategies to keep the ulcer clean and protected, medications to control blood sugar, and changes to their diet. (medicalnewstoday.com)
- Sanuwave, maker of the New dermaPACE diabetic foot ulcer treatment, received a letter from the Food and Drug Administration (FDA), asking the company wholesale nfl jerseys to run another clinical trial of its wave-based product. (safestep.net)
- Once a pressure injury (pressure ulcer) has developed, immediate treatment is required. (medscape.com)
- If Edixomed prices this appropriately, then EDX110 could become a key part of the treatment pathway of any diabetic foot ulcer, especially when mildly infected. (medscape.com)
- Another major treatment option for foot ulcers is a complete change in your lifestyle. (bestshoesfordiabetics.com)
- Transcriptomics-driven drug repositioning for the treatment of diabetic foot ulcer. (bvsalud.org)
18.6 million people worldwide1
- Importance Approximately 18.6 million people worldwide are affected by a diabetic foot ulcer each year, including 1.6 million people in the United States. (diabeticfootonline.com)
Diabetes mellitus2
- Diabetic foot ulcer is a major complication of diabetes mellitus, and probably the major component of the diabetic foot. (wikipedia.org)
- Here we present a case of a 51 year-old male diagnosed with long-standing decompensated Diabetes mellitus with a 2 year history of a foot ulcer. (faoj.org)
Toes10
- Peripheral neuropathy causes loss of pain or feeling in the toes, feet, legs, and arms due to distal nerve damage and low blood flow. (wikipedia.org)
- In that case, one or more of the toes, part or all of the foot, and sometimes part of the leg may have to be removed (amputated). (kaiserpermanente.org)
- Most common sites: plantar surface of foot (metatarsal heads and midfoot), toes (dorsal interphalangeal joints or distal tip). (hopkinsguides.com)
- They frequently appear on the tops of the feet or toes and the lower legs. (medicalnewstoday.com)
- Look at your toes, feet, and legs. (vedelan.com)
- Touch the toes, feet, and legs with different tools to check whether you have numbness. (vedelan.com)
- For instance, keep your feet raised when you sit, and squirm your toes frequently. (vedelan.com)
- Then, at that point, apply a diabetic foot lotion to the tops and bottoms of the feet, however not between the toes. (vedelan.com)
- Gently dry your feet, especially between the toes. (medlineplus.gov)
- Unless necessary, do not walk on frostbitten feet or toes. (cdc.gov)
Development of diabetic foot1
- Describe the role of diabetic peripheral neuropathy and Charcot osteoarthropathy in the development of diabetic foot ulcers. (wildirismedicaleducation.com)
Diabetic ulcers1
- To better treat these diabetic ulcers one has to improve their peripheral blood flow. (bestshoesfordiabetics.com)
Worse2
- Smoking affects blood flow and can make foot problems worse. (kaiserpermanente.org)
- The pain may be worse if the ulcer comes into contact with an object, such as a toothbrush. (medicalnewstoday.com)
Severity1
- In addition, the ulcers were assessed clinically, noting local blood flow perfusion and ulcer severity. (woundsource.com)
Prognosis1
- The relationship between diabetic foot ulcers and vitamin D levels is controversial, with conflicting data, but the authors suggest that elderly people with diabetes should undergo routine vitamin D screening or receive vitamin D supplementation to prevent the onset or improve the prognosis of diabetic foot ulcers. (desang.net)
Complication of diabetes2
- Diabetic foot lesions are responsible for more hospitalizations than any other complication of diabetes. (medscape.com)
- A diabetic foot ulcer is a common and most devastating complication of diabetes . (zorghealth.com)
Blood vessels4
- Diabetes can damage the nerve endings and blood vessels in your feet. (kaiserpermanente.org)
- Over many years, high glucose levels seriously damage blood vessels and nerves that lead to, among other things, loss of sensation in the feet and poor blood flow in the lower legs - the ulcer environment. (nwtntoday.com)
- This tightening of the small blood vessels in the feet can result in diminished blood flow making healing very difficult. (bestshoesfordiabetics.com)
- Ulcers formed by damaged small blood vessels in the skin, caused by the repeated exposure of skin to temperatures just above freezing to as high as 60 °F. (cdc.gov)
Shallow2
- While using the thermometer, Rau says his ulcer came back far less frequently, and when it did it was a quick-healing shallow crack. (nwtntoday.com)
- Venous ulcers are typically shallow, have an irregular shape, and appear near bony parts of the body, such as the ankle. (medicalnewstoday.com)
Treatments1
- What are some of the main medical treatments for diabetic foot ulcers? (healthviber.com)
Sore4
- A small skin problem like a callus, blister, or cracked skin can turn into a larger sore, called a foot ulcer. (kaiserpermanente.org)
- A new sore or ulcer. (kaiserpermanente.org)
- Certain other conditions can cause an ulcer or sore to appear on the tongue. (medicalnewstoday.com)
- An ischemic ulcer is a type of wound or sore that develops when the arteries do not deliver enough blood flow to a specific area. (medicalnewstoday.com)
Commonly2
- Diabetic complications commonly include decreased sensation in the feet and impaired wound healing. (healthviber.com)
- and Pseudomonas aeruginosa were commonly isolated in non-gangrenous ulcers . (bvsalud.org)
People10
- This study will ensure we continue to be at the cutting edge of clinical wound care research that makes a difference to people with non-healing ulcers. (newswire.com)
- People may also develop tongue ulcers when they first stop smoking. (medicalnewstoday.com)
- The NHS note that people who have several ulcers on the tongue or elsewhere in the mouth may have symptoms of other disorders, such as hand, foot, and mouth disease (HFMD) or oral lichen planus . (medicalnewstoday.com)
- People with certain conditions who experience tongue ulcers should talk to their doctor. (medicalnewstoday.com)
- The mortality rate for people with diabetic foot ulcers is 231 deaths per 1000 person-years, compared with 182 deaths per 1000 person-years in people with diabetes without foot ulcers. (diabeticfootonline.com)
- People with poorly controlled diabetes usually experience decreased foot sensation and impaired wound healing. (healthviber.com)
- People with diabetes mostly develop foot ulcers and, as a result, can experience diabetic soreness, infections, and other deformities on the feet. (vedelan.com)
- In people with advanced stages of diabetes many of these pressure points go completes unnoticed due to the effects of peripheral neuropathy and the foot does not adjust to the pressure points that a shoe is putting on the foot. (bestshoesfordiabetics.com)
- Foot ulcers are a common reason for hospital stays for people with diabetes. (medlineplus.gov)
- Most people with diabetes should have corns or calluses treated by a foot doctor. (medlineplus.gov)
Wound care3
- Diabetic ulcer of the medial aspect of left first toe before and after appropriate wound care. (medscape.com)
- It is prudent to address the underlying etiologies in diabetic foot ulcers for wound care modalities to be successful. (medscape.com)
- This protocol for a systematic review aims at identifying the beneficial and harmful effects of adding hyperbaric oxygen therapy to standard wound care for diabetic foot ulcers. (bmj.com)
Complications3
- With the rising incidence of diabetes, particularly type 2 diabetes, there is a growing demand for technologies that can effectively manage and prevent complications, including foot ulcers. (valuemarketresearch.com)
- The emphasis on preventive healthcare and increasing awareness of diabetic foot complications drive the adoption of foot ulcer sensors, which play a critical role in early detection and intervention. (valuemarketresearch.com)
- What are the complications of diabetic foot ulcers? (healthviber.com)
Osteomyelitis1
- An MRI was performed, which showed findings suggestive of osteomyelitis of the remnants of the 3 rd , 4 th and 5 th toe, the anterior portion of the cuboid bone, and the navicular bone of the right foot. (faoj.org)
Gangrene1
- Underlying digital artery disease, when compounded by an infected ulcer in close proximity, may result in complete loss of digital collaterals and precipitate gangrene. (medscape.com)
Venous1
- However, venous ulcers occur specifically due to problems with veins, while arterial ulcers occur due to problems with arteries. (medicalnewstoday.com)
Infections2
- Diabetic foot ulcers are a significant challenge in healthcare, not only because of their prevalence but also because of the alarming rise of antibiotic-resistant bacterial infections. (medscape.com)
- With Veteran's paraben and silicone-free range of products, you can take care of your feet and prevent them from infections. (vedelan.com)
Peripheral neuropathy1
- Diabetes has the potential to cause peripheral neuropathy and diminished blood flow, thereby elevating the likelihood of developing foot ulcers. (valuemarketresearch.com)
Occur3
- In this article, we discuss tongue ulcers in more detail, including why they occur, their symptoms, and how to treat them. (medicalnewstoday.com)
- Activity and lower cholesterol levels can usually slowly reverse the signs of poor peripheral blood flow and this can help healing in the feet where foot ulcerations occur. (bestshoesfordiabetics.com)
- An injury of the feet resulting from prolonged exposure to wet and cold conditions that can occur at temperatures as high as 60 °F if the feet are constantly wet. (cdc.gov)
Symptoms3
- Although tongue ulcers tend to clear up on their own, various home remedies may help ease the symptoms during the healing process. (medicalnewstoday.com)
- OTC medications can be a helpful remedy for symptoms of a tongue ulcer. (medicalnewstoday.com)
- What are the main signs and symptoms of diabetic foot ulcers? (healthviber.com)
Care11
- Prior history of foot disease, foot deformities that produce abnormally high forces of pressure, callus at pressure areas renal failure, oedema, impaired ability to look after personal care (e.g. visual impairment) are further risk factors for diabetic foot ulcer. (wikipedia.org)
- In this case, the feces of endangered species could turn out to be a vital asset in battling antibiotic resistance, thus affecting diabetic foot care in ways we never imagined possible. (medscape.com)
- Once an ulcer is noticed, seek podiatric medical care immediately. (healthyfeetstore.com)
- Upon completion of this course, you will have gained up-to-date knowledge to care for individuals at risk for developing diabetic foot ulcers and to assess and treat those with diabetic foot ulcers. (wildirismedicaleducation.com)
- Summarize the importance of preventive measures for diabetic foot care. (wildirismedicaleducation.com)
- A diabetic foot ulcer (DFU) is the most frequently occurring complication associated with diabetes and one that healthcare providers will encounter across the continuum of care. (wildirismedicaleducation.com)
- Regulatory support, integration with healthcare systems, and the emphasis on personalized care plans underscore the pivotal role of foot ulcer sensors in diabetic foot health management, positioning them as essential tools in preventive care strategies. (valuemarketresearch.com)
- Care for diabetic foot pain might include a specialist who works in the feet, called a podiatrist. (vedelan.com)
- Have your feet checked at every visit with a medical care practitioner. (vedelan.com)
- If you have spent any amount of time researching better practices in diabetic foot care you've probably found that wearing the right shoes and socks can help. (bestshoesfordiabetics.com)
- Follow your health care provider's instructions on how to take care of your feet. (medlineplus.gov)
20201
- 2020. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_Diabetes_Guide/547054/all/Foot_Ulcers. (hopkinsguides.com)