Fusobacterium
Fusobacterium nucleatum
Fusobacterium necrophorum
Bacteria, Anaerobic
Bacteroides
Bacteroidaceae
Porphyromonas
Veillonella
Peptostreptococcus
Lemierre Syndrome
Liver Abscess
Prevotella intermedia
Mouth
Bacteria, Aerobic
Periodontitis
Eubacterium
Pathogenesis of cancrum oris (noma): confounding interactions of malnutrition with infection. (1/161)
This study showed that impoverished Nigerian children at risk for cancrum oris (noma) had significantly reduced plasma concentrations of zinc (< 10.8 micromol/L), retinol (< 1.05 micromol/L), ascorbate (< 11 micromol/L), and the essential amino acids, with prominently increased plasma and saliva levels of free cortisol, compared with their healthy counterparts. The nutrient deficiencies, in concert with previously reported widespread viral infections (measles, herpesviruses) in the children, would impair oral mucosal immunity. We postulate, subject to additional studies, that evolution of the oral mucosal ulcers including acute necrotizing gingivitis to noma is triggered by a consortium of microorganisms of which Fusobacterium necrophorum is a key component. Fusobacterium necrophorum elaborates several dermonecrotic toxic metabolites and is acquired by the impoverished children via fecal contamination resulting from shared residential facilities with animals and very poor environmental sanitation. (+info)Lemierre's syndrome (necrobacillosis). (2/161)
Lemierre's syndrome or postanginal septicaemia (necrobacillosis) is caused by an acute oropharyngeal infection with secondary septic thrombophlebitis of the internal jugular vein and frequent metastatic infections. Fusobacterium necrophorum is the most common pathogen isolated from the patients. The interval between the oropharyngeal infection and the onset of the septicaemia is usually short. The most common sites of septic embolisms are the lungs and joints, and other locations can be affected. A high degree of clinical suspicion is needed to diagnose the syndrome. Computed tomography of the neck with contrast is the most useful study to detect internal jugular vein thrombosis. Treatment includes intravenous antibiotic therapy and drainage of septic foci. The role of anticoagulation is controversial. Ligation or excision of the internal jugular vein may be needed in some cases. (+info)Phylogenetic analysis of Fusobacterium alocis and Fusobacterium sulci based on 16S rRNA gene sequences: proposal of Filifactor alocis (Cato, Moore and Moore) comb. nov. and Eubacterium sulci (Cato, Moore and Moore) comb. nov. (3/161)
Genes encoding the 16S rRNA of Fusobacterium alocis ATCC 35896T and Fusobacterium sulci ATCC 35585T were sequenced. These sequences did not have any affinity with the 16S rRNA gene sequences of members of the genus Fusobacterium. Fusobacterium alocis ATCC 35896T and Fusobacterium sulci ATCC 35585T belonged to Clostridium cluster XI; the species most closely related to these strains were Filifactor villosus NCTC 11220T and Eubacterium infirmum W1471, respectively. Two new combinations are proposed: Filifactor alocis (Cato, Moore and Moore) comb. nov. (type strain ATCC 35896T) and Eubacterium sulci (Cato, Moore and Moore) comb. nov. (type strain ATCC 35585T). (+info)Serological study of trichloroacetic acid extracts of Bacteroides fragilis. (4/161)
Immunodiffusion techniques were used on trichloroacetic acid extracts from 10 strains of Bacteroides fragilis in detecting precipitating antibodies against this species in immune rabbit sera. Species and even strain specificities were observed in these precipitin reactions. Multiple antigens were detected in the extracts from some strains, whereas only one precipitin band per extract developed during agar-gel diffusion tests of others. The antigen extracts were found to be both heat stable and resistant to hydrolysis by alpha-chymotrypsin. Four serological patterns were demonstrated in homologous and heterologous reactions with the B. fragilis. antigen-antibody systems used. The results showed that some strains were serologically distinct from others, indicating that the strains tested are of more than one serotype. (+info)Detection of tetQ and ermF antibiotic resistance genes in Prevotella and Porphyromonas isolates from clinical specimens and resident microbiota of humans. (5/161)
Gram-negative anaerobes belonging to the genera Fusobacterium, Prevotella and Porphyromonas were investigated for the presence of tetQ and ermF, which have been shown to be spread by conjugal elements. One hundred isolates from either sites of infection or various body sites in healthy subjects were studied. PCR was used to detect tetQ, and DNA-DNA hybridization studies on EcoRI chromosomal digests were undertaken to detect the presence of tetQ and ermF. Antibiotic sensitivity assays were performed on selected isolates to detect tetracycline, erythromycin and penicillin resistance. Twenty Fusobacterium isolates lacked tetQ, and were tetracycline sensitive. Twenty per cent of Prevotella spp. isolates both from clinical specimens and from healthy subjects were found to possess tetQ. Of 20 Porphyromonas isolates tested, one (Porphyromonas levii) from a case of bacterial vaginosis was shown to possess tetQ in the chromosome. The presence of tetQ was always associated with tetracycline resistance. Four isolates of Prevotella melaninogenica and one isolate of Prevotella were ermF-positive, although expression of erythromycin resistance was not consistently associated with detection of this gene. Antibiotic resistance phenotypes of Prevotella isolates were shown to be related to specific chromosomal restriction patterns by hybridization studies: tetracycline resistance and tetracycline/erythromycin resistance are conferred by Bacteroides tetracycline-resistant ERL elements, whereas the tetracycline/penicillin resistance phenotype could be due to spread of elements identified in Prevotella only. Tetracycline/erythromycin-resistant and tetracycline/erythromycin/penicillin-resistant P. melaninogenica isolates were found in this study. It appeared that the presence of tetQ and ermF in Bacteroides and Prevotella contributed to the persistence of antibiotic resistance isolates within the host and to potential spread to other organisms through conjugal elements. (+info)Human necrobacillosis, with emphasis on Lemierre's syndrome. (6/161)
Lemierre's syndrome is the classical presentation of human necrobacillosis. It is characterized by a primary infection in the head in a young, previously healthy person who subsequently develops persistent high fever and disseminated metastatic abscesses, frequently including a septic thrombophlebitis of the internal jugular vein. The main pathogen is Fusobacterium necrophorum, an obligate anaerobic, pleomorphic, gram-negative rod. Clinical microbiologists have a key role in alerting clinicians and advising proper antibiotic treatment when the characteristic microscopic morphology of the pleomorphic F. necrophorum is seen in Gram stains from positive anaerobic cultures of blood and pus. Early diagnosis and prolonged appropriate antibiotic treatment with good anaerobic coverage are crucial to reduce morbidity and mortality. F. necrophorum also causes human necrobacillosis with foci caudal to the head, mainly in elderly patients with high mortality related to age and predisposing diseases, such as cancers of the primary focus. (+info)A simple method for rapid identification of Sphaerophorus necrophorus isolates. (7/161)
A hemagglutination inhibition test for the rapid identification of Sphaerophorus necrophorus is described. Erythrocytes from six species of animals were tested and human cells were found to be the best agglutination indicators. Antiserum prepared in rabbits was found to be specific for S. necrophorus hemagglutinins when tested against 20 isolates of S. necrophorus and 117 other bacteria belonging to 22 genera. The possibility of using a hemagglutination inhibition test for the detection of bovine necrobacillosis was explored. (+info)Fusobacteriosis in captive wild-caught pronghorns (Antilocapra americana). (8/161)
An outbreak of Fusobacterium necrophorum-induced septicemia occurred in a group of 40 captive wild-caught pronghorns (Antilocapra americana). Primary pododermatitis or necrotic stomatitis progressed to produce fatal septicemia with metastatic lesions in the forestomachs, lung, liver, and cecum in 38 of the animals. Two remaining animals were euthanatized because of chronic pododermatitis. Housing the animals in a pasture previously used by bovids and heavy rains with persistence of ground water pools in the pasture were contributing factors in the pathogenesis of this outbreak. (+info)Fusobacterium infections are diseases or conditions caused by the bacterial genus Fusobacterium, which are gram-negative, anaerobic bacilli. These bacteria are commonly found as normal flora in the oral cavity, gastrointestinal tract, and female genital tract. However, under certain circumstances, they can cause infections, particularly in individuals with weakened immune systems or underlying medical conditions.
Fusobacterium infections can manifest in various forms, including:
1. Oral infections: Fusobacterium nucleatum is the most common species associated with oral infections, such as periodontitis, abscesses, and Ludwig's angina.
2. Respiratory tract infections: Fusobacterium necrophorum can cause lung abscesses, empyema, and bronchitis.
3. Bloodstream infections (bacteremia): Fusobacterium species can enter the bloodstream through various routes, such as dental procedures or invasive medical procedures, leading to bacteremia. This condition can be particularly dangerous for individuals with compromised immune systems or underlying medical conditions.
4. Intra-abdominal infections: Fusobacterium species can cause intra-abdominal abscesses, peritonitis, and appendicitis.
5. Skin and soft tissue infections: Fusobacterium species can cause cellulitis, myositis, and necrotizing fasciitis.
6. Bone and joint infections: Fusobacterium species can cause osteomyelitis and septic arthritis.
7. Central nervous system infections: Fusobacterium species can cause meningitis and brain abscesses, although these are rare.
Fusobacterium infections can be challenging to treat due to their anaerobic nature and resistance to certain antibiotics. Therefore, it is essential to seek medical attention if you suspect a Fusobacterium infection. Treatment typically involves the use of appropriate antibiotics, such as metronidazole or clindamycin, and sometimes surgical intervention may be necessary.
Fusobacterium is a genus of obligate anaerobic, gram-negative, non-spore forming bacilli that are commonly found as normal flora in the human oral cavity, gastrointestinal tract, and female genital tract. Some species of Fusobacterium have been associated with various clinical infections and diseases, such as periodontal disease, abscesses, bacteremia, endocarditis, and inflammatory bowel disease.
Fusobacterium nucleatum is the most well-known species in this genus and has been extensively studied for its role in various diseases. It is a opportunistic pathogen that can cause severe infections in immunocompromised individuals or when it invades damaged tissues. Fusobacterium necrophorum, another important species, is a leading cause of Lemierre's syndrome, a rare but serious condition characterized by septic thrombophlebitis of the internal jugular vein and metastatic infections.
Fusobacteria are known to have a complex relationship with other microorganisms and host cells, and they can form biofilms that contribute to their virulence and persistence in the host. Further research is needed to fully understand the pathogenic mechanisms of Fusobacterium species and to develop effective strategies for prevention and treatment of Fusobacterium-associated diseases.
"Fusobacterium nucleatum" is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity and plays a significant role in periodontal disease. It has also been implicated in various extraintestinal infections, including septicemia, brain abscesses, and lung and liver infections. This bacterium is known to have a variety of virulence factors that contribute to its pathogenicity, such as the ability to adhere to and invade host cells, produce biofilms, and evade the immune response. It has been linked to several systemic diseases, including colorectal cancer, where it may promote tumor growth and progression through various mechanisms.
Fusobacterium necrophorum is a gram-negative, anaerobic, non-spore forming rod-shaped bacterium. It is a normal inhabitant of the oral cavity, gastrointestinal tract and urogenital tract of humans and animals. However, it can cause various infections in humans, particularly in individuals with compromised immune systems.
Fusobacterium necrophorum is well known for its association with severe clinical conditions such as Lemierre's syndrome, which is a rare but life-threatening condition characterized by septic thrombophlebitis of the internal jugular vein and metastatic infections. It can also cause other suppurative infections including bronchitis, pneumonia, meningitis, brain abscesses, and septicemia. In addition, Fusobacterium necrophorum has been implicated in the pathogenesis of certain types of periodontal disease and is a significant cause of bacterial peritonitis in cirrhotic patients.
Anaerobic bacteria are a type of bacteria that do not require oxygen to grow and survive. Instead, they can grow in environments that have little or no oxygen. Some anaerobic bacteria can even be harmed or killed by exposure to oxygen. These bacteria play important roles in many natural processes, such as decomposition and the breakdown of organic matter in the digestive system. However, some anaerobic bacteria can also cause disease in humans and animals, particularly when they infect areas of the body that are normally oxygen-rich. Examples of anaerobic bacterial infections include tetanus, gas gangrene, and dental abscesses.
Bacteroides are a genus of gram-negative, anaerobic, rod-shaped bacteria that are normally present in the human gastrointestinal tract. They are part of the normal gut microbiota and play an important role in breaking down complex carbohydrates and other substances in the gut. However, some species of Bacteroides can cause opportunistic infections, particularly in individuals with weakened immune systems or when they spread to other parts of the body. They are resistant to many commonly used antibiotics, making infections caused by these bacteria difficult to treat.
Bacteroidaceae is a family of gram-negative, anaerobic or facultatively anaerobic, non-spore forming bacteria that are commonly found in the human gastrointestinal tract. They are rod-shaped and can vary in size and shape. Bacteroidaceae are important breakdowners of complex carbohydrates and proteins in the gut, and play a significant role in maintaining the health and homeostasis of the intestinal microbiota. Some members of this family can also be opportunistic pathogens and have been associated with various infections and diseases, such as abscesses, bacteremia, and periodontal disease.
"Porphyromonas" is a genus of gram-negative, anaerobic bacteria that are commonly found in the human oral cavity and other areas of the body. One species, "Porphyromonas gingivalis," is a major contributor to chronic periodontitis, a severe form of gum disease. These bacteria are also associated with various systemic diseases, including atherosclerosis, rheumatoid arthritis, and aspiration pneumonia. The name "Porphyromonas" comes from the Greek words "porphyra," meaning purple, and "monas," meaning unit, referring to the bacteria's ability to produce porphyrins, which are pigments that can give a purple color to their colonies.
Veillonella is a genus of Gram-negative, anaerobic, non-spore-forming, coccoid or rod-shaped bacteria. These bacteria are commonly found as normal flora in the human mouth, intestines, and female genital tract. They are known to be obligate parasites, meaning they rely on other organisms for nutrients and energy. Veillonella species are often associated with dental caries and have been implicated in various infections such as bacteremia, endocarditis, pneumonia, and wound infections, particularly in immunocompromised individuals or those with underlying medical conditions. Proper identification of Veillonella species is important for the diagnosis and treatment of these infections.
Peptostreptococcus is a genus of Gram-positive, anaerobic, coccus-shaped bacteria that are commonly found as normal flora in the human mouth, gastrointestinal tract, and female genital tract. These organisms can become pathogenic and cause a variety of infections, particularly in individuals with compromised immune systems or following surgical procedures. Infections caused by Peptostreptococcus species can include abscesses, endocarditis, bacteremia, and joint infections. Proper identification and antibiotic susceptibility testing are essential for the effective treatment of these infections.
Lemierre Syndrome, also known as post-anginal septicemia or necrobacillosis, is a rare but serious medical condition that typically follows a recent pharyngitis (throat infection) or upper respiratory tract infection. It is characterized by the spread of infection from the oropharynx to the internal jugular vein and subsequent septicemia (bloodstream infection), leading to metastatic infectious complications, most commonly affecting the lungs. The causative organism is usually a bacterium called Fusobacterium necrophorum.
The syndrome was first described by French physician André Lemierre in 1936. Symptoms may include fever, chills, severe neck pain and stiffness, difficulty swallowing, swelling of the jaw or neck, shortness of breath, and the formation of abscesses in various parts of the body. Rapid diagnosis and appropriate antibiotic treatment are crucial to prevent potentially life-threatening complications.
A liver abscess is a localized collection of pus within the liver tissue caused by an infection. It can result from various sources such as bacterial or amebic infections that spread through the bloodstream, bile ducts, or directly from nearby organs. The abscess may cause symptoms like fever, pain in the upper right abdomen, nausea, vomiting, and weight loss. If left untreated, a liver abscess can lead to serious complications, including sepsis and organ failure. Diagnosis typically involves imaging tests like ultrasound or CT scan, followed by drainage of the pus and antibiotic treatment.
Prevotella intermedia is a gram-negative, anaerobic, rod-shaped bacterium that is commonly found in the oral cavity, upper respiratory tract, and gastrointestinal tract. It is a normal resident of the human microbiota but can also be an opportunistic pathogen, causing various types of infections such as periodontitis, endocarditis, and brain abscesses. P. intermedia has been associated with several diseases, including respiratory tract infections, bacteremia, and joint infections. It is often found in mixed infections with other anaerobic bacteria. Proper identification of this organism is important for the selection of appropriate antimicrobial therapy.
In medical terms, the mouth is officially referred to as the oral cavity. It is the first part of the digestive tract and includes several structures: the lips, vestibule (the space enclosed by the lips and teeth), teeth, gingiva (gums), hard and soft palate, tongue, floor of the mouth, and salivary glands. The mouth is responsible for several functions including speaking, swallowing, breathing, and eating, as it is the initial point of ingestion where food is broken down through mechanical and chemical processes, beginning the digestive process.
Aerobic bacteria are a type of bacteria that require oxygen to live and grow. These bacteria use oxygen as the final electron acceptor in their respiratory chain to generate energy in the form of ATP (adenosine triphosphate). Aerobic bacteria can be found in various environments, including soil, water, and the air, as well as on the surfaces of living things. Some examples of aerobic bacteria include species of Pseudomonas, Bacillus, and Staphylococcus.
It's worth noting that some bacteria can switch between aerobic and anaerobic metabolism depending on the availability of oxygen. These bacteria are called facultative anaerobes. In contrast, obligate anaerobes are bacteria that cannot tolerate oxygen and will die in its presence.
Periodontitis is a severe form of gum disease that damages the soft tissue and destroys the bone supporting your teeth. If left untreated, it can lead to tooth loss. It is caused by the buildup of plaque, a sticky film of bacteria that constantly forms on our teeth. The body's immune system fights the bacterial infection, which causes an inflammatory response. If the inflammation continues for a long time, it can damage the tissues and bones that support the teeth.
The early stage of periodontitis is called gingivitis, which is characterized by red, swollen gums that bleed easily when brushed or flossed. When gingivitis is not treated, it can advance to periodontitis. In addition to plaque, other factors that increase the risk of developing periodontitis include smoking or using tobacco products, poor oral hygiene, diabetes, a weakened immune system, and genetic factors.
Regular dental checkups and good oral hygiene practices, such as brushing twice a day, flossing daily, and using an antimicrobial mouth rinse, can help prevent periodontitis. Treatment for periodontitis may include deep cleaning procedures, medications, or surgery in severe cases.
"Eubacterium" is a genus of Gram-positive, obligately anaerobic, non-sporeforming bacteria that are commonly found in the human gastrointestinal tract. These bacteria are typically rod-shaped and can be either straight or curved. They play an important role in the breakdown of complex carbohydrates and the production of short-chain fatty acids in the gut, which are beneficial for host health. Some species of Eubacterium have also been shown to have probiotic properties and may provide health benefits when consumed in appropriate quantities. However, other species can be opportunistic pathogens and cause infections under certain circumstances.
Actinomyces is a genus of gram-positive, rod-shaped bacteria that are normal inhabitants of the human mouth, colon, and urogenital tract. Under certain conditions, such as poor oral hygiene or tissue trauma, these bacteria can cause infections known as actinomycosis. These infections often involve the formation of abscesses or granulomas and can affect various tissues, including the lungs, mouth, and female reproductive organs. Actinomyces species are also known to form complex communities called biofilms, which can contribute to their ability to cause infection.
Fusobacterium
Fusobacterium necrophorum
Infections associated with diseases
Dysbiosis
Impacted wisdom teeth
Lemierre's syndrome
Omasitis
Anaerobic infection
Blain (animal disease)
Doxycycline
Fusobacterium nucleatum
Foot rot
Chorioamnionitis
Necrotizing gingivitis
Pharynx
Vincent's angina
Metronidazole
Human Genome Sequencing Center
Brain abscess
Dentures
Ludwig's angina
FMN riboswitch
Mastoiditis
Sulfadimethoxine
Animal attack
Peritonsillar abscess
Thrush (horse)
Adenoid
List of bacterial vaginosis microbiota
Septic embolism
COVID-19-Associated Fusobacterium nucleatum Bacteremia, Belgium - Volume 27, Number 3-March 2021 - Emerging Infectious Diseases...
Invasive Fusobacterium Infections in Children: A Retrospective Multicenter Study<...
Fusobacterium - Wikipedia
Bacterial Pharyngitis: Background, Pathophysiology, Epidemiology
Development of a multiplex PCR for diagnostics of relevant bacteria in throat infections; Fusobacterium necrophorum,...
Tea polyphenols inhibit the growth and virulence properties of Fusobacterium nucleatum | Scientific Reports
DailyMed - DOXYCYCLINE injection, powder, lyophilized, for solution
DailyMed - DOXYCYCLINE HYCLATE capsule
Short blood culture time-to-positivity in Fusobacterium necrophorum bacteremia is associated with Lemierre's syndrome | Lund...
Advanced Search Results - Public Health Image Library(PHIL)
Pediatric Mastoiditis Treatment & Management: Approach Considerations, Antimicrobial Therapy, Mastoidectomy, Tympanoplasty, and...
Faculty Achievements | News and Communications Services | Communications and Marketing | Kansas State University
Suzuki M[Author] - Search Results - PubMed
Tetracycline dosing, indications, interactions, adverse effects, and more
Iijima K[au] - Search Results - PubMed
Endometriosis Linked to Bacterial Infection, Suggesting Treatment With Antibiotics | GenomeWeb
Declomycin (demeclocycline) dosing, indications, interactions, adverse effects, and more
Delayed diagnosis of Lemierre's syndrome in a patient with severe coronavirus disease 2019: importance of comprehensive oral...
Vibramycin Intravenous (Doxycycline hyclate): Uses, Dosage, Side Effects, Interactions, Warning
Necrotic Rhinitis in Pigs - Respiratory System - Merck Veterinary Manual
Fusobacterium Linked To Colorectal Cancer
RX List database - use generic or medication brand name - GlobalRPH
Image Quiz: The outcome of a food fight
Oral hygiene and severity of COVID-19 - the connection | Century Smile
HuGE Navigator|Genopedia|PHGKB
Mucinases and sialidases: their role in the pathogenesis of sexually transmitted infections in the female genital tract |...
Jørgen Steen Agerholm - Resultat
Microbiology of Odontogenic Infections - Adjunctive and Prophylactic Use of Antibacterial Agents in Dentistry - Dentalcare
Bioinformatics analysis reveals immune prognostic markers for overall survival of colorectal cancer patients: a novel machine...
Actinomycosis with Fusobacterium empyema | BMJ Case Reports
Necrophorum12
- F. necrophorum has been found as a common pathogen in the diagnostic of peritonsillar abscess and is more prevalent than other bacteria regarding this infection. (wikipedia.org)
- F. necrophorum commonly infects animals, causing liver abscesses and necrodic diseases, and can combine with other pathogenic bacteria to cause various infections such as foot rot and uterine infections. (wikipedia.org)
- Fusobacterium necrophorum, Streptococcus pyogenes and S. dysgalactiae subspecies equisimilis. (lu.se)
- Recently, we showed that S. pyogenes and F. necrophorum are equally associated with the development of complications in findings in tonsillitis (1), and F. necrophorum has been described as the most common cause of throat abscess (2), as well as an increasing cause of invasive infections in Sweden (3). (lu.se)
- No study has investigated the presence of F. necrophorum as a cause of throat infections in any low-income country, but in studies from Nigeria, the bacterium has been seen as a potential cause of the orogangrenous and life-threatening infection noma, which mainly affects children suffering from starvation (10, 11). (lu.se)
- Nygren D, Wasserstrom L, Holm K, Torisson G. Associations Between Findings of Fusobacterium necrophorum or beta-Hemolytic Streptococci and Complications in Pharyngotonsillitis-A Registry-Based Study in Southern Sweden. (lu.se)
- Nygren D, Holm K. Invasive infections with Fusobacterium necrophorum including Lemierre's syndrome: an 8-year Swedish nationwide retrospective study. (lu.se)
- Necrotic rhinitis follows injury to the oral or nasal mucosa and is often accompanied by infection with Fusobacterium necrophorum . (merckvetmanual.com)
- Fusobacterium necrophorum is commonly isolated from the lesion and undoubtedly contributes to necrotic rhinitis, but other types of organisms are frequently present. (merckvetmanual.com)
- Research has mainly focused on bacterial infections including the role of Bacillus licheniformis and Fusobacterium necrophorum as abortifacients. (ku.dk)
- This disease is necrosis of the sphincter of the mammary gland and is usually associated with secondary Fusobacterium necrophorum infection. (roshddanehkhavaran.com)
- First large-scale study of antimicrobial susceptibility data, and genetic resistance determinants, in Fusobacterium necrophorum highlighting the importance of continuing focused susceptibility trend surveillance. (cdc.gov)
Porphyromonas10
- Over one half of all gram-negative anaerobic bacteria (eg, pigmented Prevotella, Porphyromonas, Bacteroides, and Fusobacterium ) are resistant to penicillins because they produce beta-lactamase. (medscape.com)
- Some of the bacteria present in the mouth that could cause such infections include "Porphyromonas gingivalis, Fusobacterium nucleatum, Prevotella intermedia," they wrote. (centurysmile.com)
- In a recent study, persons with mouth infections involving Porphyromonas gingivalis, Pg, and Fusobacterium nucleatum, Fn, have a significantly increased risk of developing rheumatoid disease. (washdent.com)
- The present research aims to examine a periodontal disease model in which specific pathogen-free Wistar rats are orally exposed to Porphyromonas gingivalis associated with Fusobacterium nucleatum . (bvsalud.org)
- The experimental animals were repeatedly infected with Porphyromonas gingivalis and Fusobacterium nucleatum for one week. (bvsalud.org)
- Our study showed that four weeks following infection with Porphyromonas gingivalis and Fusobacterium nucleatum bone loss in Wistar rats could be identified. (bvsalud.org)
- Este estudo teve o objetivo de induzir doença periodontal pela inoculação oral da Porphyromonas gingivalis associada à Fusobacterium nucleatum em ratos da linhagem Wistar. (bvsalud.org)
- Os animais do grupo experimental foram infectados oralmente por Porphyromonas gingivalis associada à Fusobacterium nucleatum durante uma semana. (bvsalud.org)
- O presente estudo demonstrou que 4 semanas de infecção pelas bactérias Porphyromonas gingivalis e Fusobacterium nucleatum promoveu perda óssea em ratos da linhagem Wistar. (bvsalud.org)
- the most commonly isolated anaerobes are various species of Fusobacterium, Bacteroides, Porphyromonas, and Prevotella. (cdc.gov)
Bacteria20
- Fusobacterium is a genus of obligate anaerobic, Gram-negative, non-sporeforming bacteria belonging to Gracilicutes. (wikipedia.org)
- F. russi is a common bacteria in canine and feline oral cavities and can lead to the infection of puncture wounds if transferred to humans from bites. (wikipedia.org)
- The development of antibiotic resistance in periodontopathogens is a major issue given that these bacteria may migrate from the oral cavity to other organs where they may cause infections or transfer their antibiotic resistances to other bacterial species. (nature.com)
- To reduce the development of drug-resistant bacteria and maintain the effectiveness of doxycycline for injection, USP and other antibacterial drugs, doxycycline for injection, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
- The two independent teams found a potential association between colon cancer and a microorganism after they identified that Fusobacterium, a single genus of bacteria, was found more often in colon cancer tissue compared to normal tissue. (medicalnewstoday.com)
- They tried to explore if high levels of bacteria or bacterial super-infections and complications of bacterial infections such as pneumonia, sepsis, and respiratory distress syndrome could be associated with poor outcome from COVID-19. (centurysmile.com)
- They explained that periodontitis or infection of the gums is one of the most prevalent causes of harmful bacteria in the mouth. (centurysmile.com)
- These bacteria lead to the formation of cytokines such as Interleukin 1 (IL1) and Tumor necrosis factor (TNF), which can be detected in the saliva and can reach the lungs leading to infection within them. (centurysmile.com)
- Bacteria Detected in Odontogenic Infections. (dentalcare.com)
- It is the most common species of anaerobic bacteria isolated from human soft tissue infections. (lookformedical.com)
- Infections with bacteria of the genus BACTEROIDES . (lookformedical.com)
- As the infection worsens, the body responds with needed but sometimes destructive inflammation due to selected type of bacteria. (washdent.com)
- Managing the gum infection, first by testing for the specific bacteria involved, and then tailoring the specific treatment, will prevent tooth loss. (washdent.com)
- Those with melanoma also had a higher concentration of Fusobacterium bacteria ( which has been known to cause infections 3 ) when compared to the control group. (mindbodygreen.com)
- The most probable cause of this lesion is Fusobacterium necroform bacteria. (roshddanehkhavaran.com)
- Flagyl is a medication used to treat infections caused by bacteria and parasites. (air2bhutan.com)
- It works by killing bacteria and other microorganisms that cause infections. (air2bhutan.com)
- However, it is important to note that not all urinary tract infections are caused by bacteria that are susceptible to Flagyl. (air2bhutan.com)
- Discussions with clinicians in multiple states raised concerns about a possible increase in pediatric intracranial infections, particularly those caused by Streptococcus bacteria, during the past year and the possible contributing role of SARS-CoV-2 infection. (medscape.com)
- Discussions with clinicians in multiple states raised concerns (intracranial abscess and granuloma) or G06.2 (extradural and about a possible increase in pediatric intracranial infections, subdural abscess, unspecified) during the study period were particularly those caused by Streptococcus bacteria, during the included. (cdc.gov)
Species18
- F. nucleatum is found in humans more so than any other species of Fusobacterium. (wikipedia.org)
- They used FISH probes informed by publicly available bacterial 16S ribosomal RNA databases to search for Fusobacterium species found in some vaginal samples in past studies. (genomeweb.com)
- Escherichia coli, Enterobacter aerogenes, Shigella species, Acinetobacter species, Haemophilus influenzae (respiratory infections), Klebsiella species (respiratory and urinary infections). (rxlist.com)
- Infection with filamentous rods-suspect Actinomyces species infection is correct! (dvm360.com)
- The primary differentials for filamentous rods are Actinomyces , Nocardia , and Fusobacterium species infections. (dvm360.com)
- Both Actinomyces and Nocardia species are weakly gram-positive, while Fusobacterium species are gram-negative. (dvm360.com)
- Actinomyces and Fusobacterium species are anaerobic, while Nocardia species are a slow-growing aerobe. (dvm360.com)
- In this case, anaerobic culture results were positive for Actinomyces species, and infection was probably initiated by a bite wound. (dvm360.com)
- The pleural fluid was macroscopically consistent with pus and microbiology showed growth of gram-positive bacilli, Actinomyces meyeri as well as the Fusobacterium species. (bmj.com)
- The awareness that the Actinomyces species and the Fusobacterium species through their synergistic interaction may cause empyema, may lead to a timely diagnosis and treatment. (bmj.com)
- Some species are pathogenic and occur in various purulent or gangrenous infections. (lookformedical.com)
- Prevalence of Fusobacterium Species in Endodontic Infections Detected With Molecular Methods: Systematic Review and Meta-Analysis. (bvsalud.org)
- Актиномікоз Actinomycosis is a chronic localized or hematogenous anaerobic infection caused by Actinomyces israelii and other species of Actinomyces . (msdmanuals.com)
- Minocycline is indicated for treatment of infections caused by the following: Escherichia coli, Enterobacter aerogenes,Shigella species, Acinetobacter species, Respiratory tract infections caused by Haemophilus influenza, Respiratory tract and urinary tract infections caused by Klebsiella species, Upper respiratory tract infections caused by Streptococcus pneumonia, Skin and skin structure infections caused by Staphylococcus aureus. (mlivehosted.com)
- Infections caused by Clostridium species. (mlivehosted.com)
- Gram-positive organisms such as Staphylococcus aureus and Streptococcus species are the most commonly isolated organisms in patients with pyogenic vertebral infections. (wheelessonline.com)
- Lancefield groups K through V are streptococcal species of limited virulence that can cause infections in people who are immunocompromised. (msdmanuals.com)
- [ 1 ] Pediatric bacterial brain abscesses, epidural empyemas, and subdural empyemas, rare complications of respiratory infections and sinusitis, are often caused by Streptococcus species but might also be polymicrobial or caused by other genera, such as Staphylococcus . (medscape.com)
Streptococcus1
- Pneumococcal Infections Streptococcus pneumoniae (pneumococci) are gram-positive, alpha-hemolytic, aerobic, encapsulated diplococci. (msdmanuals.com)
Colorectal cancer9
- Strains of Fusobacterium can cause several human diseases and infections, including periodontal diseases, Lemierre's syndrome, oral, head, and neck infections, as well as colorectal cancer and topical skin ulcers. (wikipedia.org)
- According to two new investigations published online in Genome Research , independent investigation teams have for the first time discovered a specific microorganism called Fusobacterium to be linked with human colorectal cancer . (medicalnewstoday.com)
- According to this new research (freely available), published 18th October 2011, the same might be true for a microbe called Fusobacterium nucleatum and colorectal cancer. (microbes.me)
- After screening colorectal cancer tissue specimens and matched controls, the researchers (to their apparent surprise) found a significant over-representation of genetic material from Fusobacterium nucleatum associated with tumors. (microbes.me)
- While Fusobacterium has previously been implicated in colorectal cancer, Providencia is a novel tumor-associated agent which has not been identified in previous studies. (biomedcentral.com)
- Additionally, we identified a clear, significant enrichment of predicted virulence-associated genes in the colorectal cancer microenvironment, likely dependent upon the genomes of Fusobacterium and Providencia . (biomedcentral.com)
- FadA-positive Fusobacterium nucleatum is prevalent in the biopsy specimens of Iranian patients with colorectal cancer. (rojetechnologies.com)
- A Fusobacterium nucleatum vaccine to help protect against colorectal cancer? (microbiomepost.com)
- For example, Fusobacterium nucleatum - an oral commensal that can cause different infections in the mouth - has been associated with the development of colorectal cancer. (microbiomepost.com)
Clostridium1
- Also indicated in coccidiosis, Trichomoniasis, Giardiasis, Amoebiasis and anaerobic infections like clostridium and Fusobacterium. (indiangenomix.net)
Periodontitis3
- Fusobacterium nucleatum plays a key role in creating the pathogenic subgingival biofilm that initiates destructive periodontitis. (nature.com)
- Vibramycin I.V. ( doxycycline hyclate) is a tetracycline antibiotic used to treat many different bacterial infections such as urinary tract infections acne gonorrhea and chlamydia periodontitis (gum disease) and others. (rxlist.com)
- Periodontitis was induced by specific infection with P. gingivalis and F. nucleatum . (bvsalud.org)
Haemophilus1
- The global epidemiology of Haemophilus ducreyi infections microbiological diagnoses. (cdc.gov)
Lemierre's1
- Lemierre's syndrome is characterized by septic thrombophlebitis of the internal jugular vein, typically due to pharyngeal infection. (biomedcentral.com)
Invasive6
- 18 years old who had been admitted with a diagnosis of invasive Fusobacterium infection (IFI) between January 2010 and April 2020. (tau.ac.il)
- This protein, located peripherally on the cell wall, is required for invasive infection. (medscape.com)
- S. pyogenes causes, in addition to complicated and invasive infections and the non-purulent complications, rheumatic fever and heart disease, but in high-income countries this rheumatic complication has almost disappeared as socioeconomics have improved (4-8). (lu.se)
- F. nucleatum is well known for its invasive properties 10 , which may allow it to enter the bloodstream, migrate, and cause infections elsewhere in the body 11 . (nature.com)
- Three major routes of spread are: (1) hematogenous spread from a distant infection, (2) direct inoculation from trauma, (3) direct inoculation following invasive spinal diagnostic procedures and from spinal surgery. (wheelessonline.com)
- Rarely, bite and scratch wounds may result in serious systemic infections caused by invasive pathogens such as Capnocytophaga canimorsus, Bergeyella zoohelcum, CDC group NO-1, and Bartonella spp. (cdc.gov)
Prevalent1
- Fusobacterium nucleatum infection is prevalent in colorectal carcinoma. (microbes.me)
Soft tissue infections3
- Staphylococcus aureus, respiratory skin and soft tissue infections. (rxlist.com)
- Its organisms are opportunistic pathogens causing bacteremias and soft tissue infections. (lookformedical.com)
- Клостридіальні інфекції м'яких тканин Clostridial soft-tissue infections include cellulitis, myositis, and clostridial myonecrosis. (msdmanuals.com)
Bacterium6
- Our data support a mechanism for the pathogenesis of endometriosis via Fusobacterium infection and suggest that eradication of this bacterium could be an approach to treat endometriosis," Kondo and his colleagues wrote. (genomeweb.com)
- This was especially surprising because although Fusobacterium, the bacterium we found in colon tumors, is a known pathogen, it is a very rare constituent of the normal gut microbiome and has not been associated previously with cancer. (medicalnewstoday.com)
- Eradication of this bacterium by antibiotic treatment could be an approach to treat endometriosis for women who are positive for fusobacteria infection, and such women could be easily identified by vaginal swab or uterus swab,' he said. (toppersonalhealth.com)
- Infection with a bacterium that causes gum disease and bad breath may increase the risk of heart disease, shows a study published today in eLife. (greenleafready.info)
- It may also indicate that treatments for colonisation or infection with the oral bacterium Fusobacterium nucleatum may help reduce heart disease risk. (greenleafready.info)
- Once the authors adjusted the results for known cardiovascular risk factors, they found that antibodies against F. nucleatum , a sign of previous or current infection by the bacterium,were linked with a slightly increased risk of a cardiovascular event. (greenleafready.info)
Urinary2
- The most common sources are urinary tract infections and the transient bacteremia caused by genitourinary procedures. (wheelessonline.com)
- Enterococcus faecalis and E. faecium cause a variety of infections, including endocarditis, urinary tract infections. (msdmanuals.com)
Nucleatum infection2
Bacteremia4
- We report 4 cases of Fusobacterium nucleatum bacteremia associated with coronavirus disease (COVID-19). (cdc.gov)
- In March and April 2020, 2 major hospitals in Brussels, Belgium, observed 4 cases of monomicrobial F. nucleatum bacteremia, all associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among patients with coronavirus disease (COVID-19). (cdc.gov)
- Increased risk for severe infection, including bacteremia, has been associated with long-term TCZ treatment when administered for non-COVID-19 indications ( 3 ). (cdc.gov)
- 5,14 That prevalence of this infection increases with age is possibly due to a number of factors: the increasing age of the population, increasing number of patients on renal replacement therapy, increasing number of patients with immunosuppressive medications and increasing rates of bacteremia due to intravascular devices and other forms of instrumentation. (wheelessonline.com)
Gram-positive2
- Ultimately, facultative and anaerobic gram-positive and gram-negative cocci and bacilli predominate in all types of odontogenic infections (Table 1). (dentalcare.com)
- Enterococcal Infections Enterococci are gram-positive, facultative anaerobic organisms. (msdmanuals.com)
Prevalence2
- In temperate regions, the prevalence of GABHS infection increases in the colder months, presumably because of the tendency of people to congregate indoors. (medscape.com)
- However, data on the prevalence of pathogens, including S. pyogenes , in throat infections in low-income countries are often lacking, and the science is flawed (6, 8). (lu.se)
Commensal2
- Fusobacterium: A commensal turned pathogen. (washdent.com)
- Our results show increased microbial diversity in the tumor microenvironment, with changes in the abundances of commensal and pathogenic bacterial taxa, including Fusobacterium and Providencia . (biomedcentral.com)
Campylobacter1
- Campylobacter fetus infections caused by Campylobacter fetus. (mlivehosted.com)
Strains2
- The number of strains per infection ranges from 1 to 10 with an average number of 4 isolates. (dentalcare.com)
- Minocycline hydrochloride tablets are indicated in the treatment of the following infections due to susceptible strains of the designated microorganisms: Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox and tick fevers caused by Rickettsiae. (mlivehosted.com)
Virulence1
- Many streptococci elaborate virulence factors, including streptolysins, DNAases, and hyaluronidase , which contribute to tissue destruction and spread of infection. (msdmanuals.com)
Lesion1
- However, mice that had been given an antibiotic to eradicate Fusobacterium saw improved lesion formation. (toppersonalhealth.com)
Pathogenic1
- A few additional sources of its pathogenic nature inclue its association with oral inflammation diseases, cancers such as pancreatic, oral, and colorectal, as well as infections of the head and neck. (wikipedia.org)
Neisseria1
- When penicillin is contraindicated, minocycline is an alternative drug in the treatment of the following infections: Uncomplicated urethritis in men due to Neisseria gonorrhoeae and for the treatment of other gonococcal infections. (mlivehosted.com)
Anaerobes1
- The obligate anaerobes that commonly cause infection can tolerate atmospheric oxygen for at least 8 hours and frequently for up to 72 hours. (msdmanuals.com)
Viral8
- The exception is when patients present overt clinical features of viral infection including rhinorrhea, cough, oral ulcers, and/or hoarseness, in which case a positive test result might reflect a carriage state. (medscape.com)
- Thus, the researchers wrote, "inadequate oral hygiene can increase the risk of inter-bacterial exchanges between the lungs and the mouth, increasing the risk of respiratory infections and potentially post-viral bacterial complications. (centurysmile.com)
- Infection usually is caused by bacterial organisms, but can also be due to viral or fungal organisms. (wheelessonline.com)
- It is a viral infection of udders, in some cases the damage to the skin of the udder is so severe and painful that it is not possible to milk the cow. (roshddanehkhavaran.com)
- It is a viral infection that affects udders and is characterized by horseshoe lesions. (roshddanehkhavaran.com)
- Can Flagyl be used to treat viral infections? (air2bhutan.com)
- Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
- RSV infection usually occurs after viral inoculation of the conjunctivae or nasal mucosa by contaminated hands. (cdc.gov)
Respiratory infections1
- For upper respiratory infections due to group A beta-hemolytic streptococci, penicillin is the usual drug of choice, including prophylaxis of rheumatic fever. (rxlist.com)
Diagnosis4
- Further diagnosis can confirm suspicions of Fusobacterium infection through blood testing or culturing the tissue. (wikipedia.org)
- The usefulness of blood culture time-to-positivity (TTP) in the diagnosis of endovascular infections has previously been shown. (lu.se)
- While not necessary to make the clinical diagnosis of PTA, imaging can confirm diagnosis, better visualize location and complexity of abscess, and distinguish from other deep space infections (retro- or parapharyngeal abscess). (emdocs.net)
- Concurrent COVID-19 diagnosis was defined as past year and the possible contributing role of SARS-CoV-2 having International Classification of Diseases, Tenth Revision infection ( 1 ). (cdc.gov)
Intracranial1
- The clinical manifestations of suppurative intracranial thrombophlebitis depend on the sinus involved, the involvement of anatomical structures within the sinus, and coexisting central nervous system infection. (hku.hk)
Penetrating wound1
- These organisms can be found in the environment (including soil) and can cause infection after a penetrating wound or migration of some type of plant fiber. (dvm360.com)
Abscesses1
- Retropharyngeal abscesses are deep neck space infections that can pose an immediate life-threatening emergency, with potential for airway compromise and other catastrophic complications. (medscape.com)
Microorganisms2
- Doxycycline has been shown to be active against most isolates of the following microorganisms, both in vitro and in clinical infections as described in the INDICATIONS AND USAGE section of the package insert for doxycycline for injection. (nih.gov)
- Infections of the spine can take the form of a primary infection of the spine or a spread of microorganisms originating from elsewhere in the body. (wheelessonline.com)
Clinical3
- This study aimed to describe the epidemiology, clinical and demographic characteristics and outcomes associated with Fusobacterium infections in hospitalized children in central Israel. (tau.ac.il)
- Fusobacterium infections often cause clinical symptoms such as a fever, inflammation, and a diseased appearance. (wikipedia.org)
- Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. (lookformedical.com)
Chlamydia1
- Nongonococcal urethritis, endocervical, or rectal infections in adults caused by Ureaplasma urealyticum or Chlamydia trachomatis. (mlivehosted.com)
Tumors2
- Both Holt and Meyerson stated that even though it is currently unclear if Fusobacterium infection is a cause or consequence of colorectal tumors, it could be extremely helpful in the clinic as a indicator for cancer. (medicalnewstoday.com)
- For example, better outcomes might be possible if, after standard therapy, an aggressive short-term course of antibiotics is used to clear F. nucleatum from sites of minimal residual disease and metastatic lesions, and then an effective vaccine is deployed to consolidate remissions by preventing re-infection and recurrence of treatment-refractory tumors," he says. (microbiomepost.com)
Complications2
- The treatment of mastoiditis depends upon the stage of the infection and presence and type of complications if present. (medscape.com)
- Complications of retropharyngeal abscess arise from mass effect, rupture of the abscess, or spread of infection. (medscape.com)
Feces1
- Research of colon cancer has also shown an overrepresentation of Fusobacterium, both in feces of patients and tumor issue itself. (wikipedia.org)
Bacterial infection1
- Lymphangitis Lymphangitis is acute bacterial infection (usually streptococcal) of peripheral lymphatic channels. (msdmanuals.com)
Antimicrobial1
- Gram stain/culture rarely changes initial management, but may help guide antimicrobial therapy in patients with complicated, extensive infection, those not improving on empiric oropharyngeal coverage, or in the immunocompromised. (emdocs.net)
Antibiotic7
- Kondo noted that the antibiotic metronidazole, which is already being used to treat the protozoan parasite behind sexually transmitted trichomoniasis infections, is known to have activity against Fusobacterium . (genomeweb.com)
- Although further studies are needed, our data suggest that targeting Fusobacterium in the endometrium by antibiotic treatment may be a therapeutic option for patients with endometriosis," the authors concluded. (genomeweb.com)
- A research group from the Graduate School of Medicine and iGCORE at Nagoya University in Japan, has discovered that using an antibiotic to target Fusobacterium reduced the formation of lesions associated with endometriosis, a gynecological disorder characterized by endometrial tissue usually found inside the uterus being found outside it. (toppersonalhealth.com)
- The team's findings strongly suggest that targeting Fusobacterium is an effective non-hormonal antibiotic treatment for endometriosis. (toppersonalhealth.com)
- Our data provide a strong and novel rationale for targeting Fusobacterium as a non-hormonal antibiotic-based treatment for endometriosis. (toppersonalhealth.com)
- No, Flagyl is an antibiotic that is specifically effective against bacterial infections. (air2bhutan.com)
- Flagyl, also known as metronidazole, is a commonly prescribed antibiotic medication used to treat a variety of bacterial and parasitic infections. (air2bhutan.com)
Streptococci1
- Sequelae of infections due to group A beta-hemolytic streptococci may include rheumatic fever and glomerulonephritis. (msdmanuals.com)
Orally1
- F. perfoetans and F. necrogenes have not been sourced from any infections in humans or animals) F. gonidiaformans is typically found in the intestines of humans and is not found orally like the other Fusobacterium. (wikipedia.org)
Significantly2
- Results: It was notable that waterpipe smokers were significantly associated with a history of oral infections. (who.int)
- In addition, the frequency of Candida albicans was higher in the subgingiva of waterpipe smokers (p = 0.023) while the frequency of Fusobacterium nucleatum was significantly lower in the subgingiva of waterpipe smokers (p = 0.036). (who.int)
Fever1
- I have a general interest in Q fever (infection with Coxiella burnetii ). (ku.dk)
Neck3
- Most common deep neck infection in children and adolescents. (emdocs.net)
- Accounts for 50% of cases of deep neck infections in this population. (emdocs.net)
- For an optimal understanding of deep space infections, knowledge of the anatomy of the fascial planes of the neck is necessary. (medscape.com)
Genetic2
- Although enormous progress has been made in understanding how coronary heart disease develops, our understanding of how infections, inflammation, and genetic risk factors contribute is still incomplete," says lead author Flavia Hodel, former PhD student at the School of Life Sciences of EPFL, Switzerland. (greenleafready.info)
- HLH has been traditionally divided into a primary form, which typically manifests in children with documented genetic abnormalities of the cytotoxic function of NK cells and T cells, and a secondary form that tends to occur at older ages in the setting of an associated condition, such as infection and malignancy, without an identifiable genetic abnormality. (medscape.com)
Pathogenesis1
- The possible contribution of mucin degrading enzymes to the pathogenesis of infection is, therefore, not to be underestimated. (bmj.com)
Pharyngitis1
- Pharyngitis, or sore throat, often is caused by infection. (medscape.com)