Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.
Manner or style of walking.
Impaired ambulation not attributed to sensory impairment or motor weakness. FRONTAL LOBE disorders; BASAL GANGLIA DISEASES (e.g., PARKINSONIAN DISORDERS); DEMENTIA, MULTI-INFARCT; ALZHEIMER DISEASE; and other conditions may be associated with gait apraxia.
Planning, organizing, and administering activities in an office.
A term used in Eastern European research literature on brain and behavior physiology for cortical functions. It refers to the highest level of integrative function of the brain, centered in the CEREBRAL CORTEX, regulating language, thought, and behavior via sensory, motor, and cognitive processes.
A form of apraxia characterized by an acquired inability to carry out a complex motor activity despite the ability to mentally formulate the action. This condition has been attributed to a disruption of connections between the dominant parietal cortex and supplementary and premotor cortical regions in both hemispheres. (From Adams et al., Principles of Neurology, 6th ed, p57)
Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.
Dense collection of cells in the caudal pontomesencephalic tegmentum known to play a role in the functional organization of the BASAL GANGLIA and in the modulation of the thalamocortical neuronal system.
A departure from the normal gait in animals.
Assessment of sensory and motor responses and reflexes that is used to determine impairment of the nervous system.
An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking.
A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Evaluation of the level of physical, physiological, or mental functioning in the older population group.
Impairment of the ability to coordinate the movements required for normal ambulation (WALKING) which may result from impairments of motor function or sensory feedback. This condition may be associated with BRAIN DISEASES (including CEREBELLAR DISEASES and BASAL GANGLIA DISEASES); SPINAL CORD DISEASES; or PERIPHERAL NERVOUS SYSTEM DISEASES.
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.
Persistent and disabling ANXIETY.
Those disorders that have a disturbance in mood as their predominant feature.
The properties, processes, and behavior of biological systems under the action of mechanical forces.
Categorical classification of MENTAL DISORDERS based on criteria sets with defining features. It is produced by the American Psychiatric Association. (DSM-IV, page xxii)
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
A behavior disorder originating in childhood in which the essential features are signs of developmentally inappropriate inattention, impulsivity, and hyperactivity. Although most individuals have symptoms of both inattention and hyperactivity-impulsivity, one or the other pattern may be predominant. The disorder is more frequent in males than females. Onset is in childhood. Symptoms often attenuate during late adolescence although a minority experience the full complement of symptoms into mid-adulthood. (From DSM-V)
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
A disorder beginning in childhood. It is marked by the presence of markedly abnormal or impaired development in social interaction and communication and a markedly restricted repertoire of activity and interest. Manifestations of the disorder vary greatly depending on the developmental level and chronological age of the individual. (DSM-V)
An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
A class of traumatic stress disorders with symptoms that last more than one month. There are various forms of post-traumatic stress disorder, depending on the time of onset and the duration of these stress symptoms. In the acute form, the duration of the symptoms is between 1 to 3 months. In the chronic form, symptoms last more than 3 months. With delayed onset, symptoms develop more than 6 months after the traumatic event.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Apparatus used to support, align, prevent, or correct deformities or to improve the function of movable parts of the body.
Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.
Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.
Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements.
Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)
Disturbances in mental processes related to learning, thinking, reasoning, and judgment.
Disorders related to substance abuse.
A general term referring to a mild to moderate degree of muscular weakness, occasionally used as a synonym for PARALYSIS (severe or complete loss of motor function). In the older literature, paresis often referred specifically to paretic neurosyphilis (see NEUROSYPHILIS). "General paresis" and "general paralysis" may still carry that connotation. Bilateral lower extremity paresis is referred to as PARAPARESIS.
The joint that is formed by the inferior articular and malleolar articular surfaces of the TIBIA; the malleolar articular surface of the FIBULA; and the medial malleolar, lateral malleolar, and superior surfaces of the TALUS.
Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.
The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.
Severe or complete loss of motor function on one side of the body. This condition is usually caused by BRAIN DISEASES that are localized to the cerebral hemisphere opposite to the side of weakness. Less frequently, BRAIN STEM lesions; cervical SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; and other conditions may manifest as hemiplegia. The term hemiparesis (see PARESIS) refers to mild to moderate weakness involving one side of the body.
Walking aids generally having two handgrips and four legs.
Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
Elements of limited time intervals, contributing to particular results or situations.
Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.
A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)
Falls due to slipping or tripping which may result in injury.
A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
Levels within a diagnostic group which are established by various measurement criteria applied to the seriousness of a patient's disorder.
Disorders characterized by recurrent TICS that may interfere with speech and other activities. Tics are sudden, rapid, nonrhythmic, stereotyped motor movements or vocalizations which may be exacerbated by stress and are generally attenuated during absorbing activities. Tic disorders are distinguished from conditions which feature other types of abnormal movements that may accompany another another condition. (From DSM-IV, 1994)
Standardized procedures utilizing rating scales or interview schedules carried out by health personnel for evaluating the degree of mental illness.
The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.
'Amputee' is a medical term used to describe an individual who has undergone the surgical removal of a limb or extremity, such as an arm, leg, foot, or hand, due to various reasons like trauma, disease, or congenital defects.
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
A synovial hinge connection formed between the bones of the FEMUR; TIBIA; and PATELLA.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Long-term follow-up in diabetic Charcot feet with spontaneous onset. (1/731)

OBJECTIVE: To assess the long-term results after Charcot breakdown with spontaneous onset in diabetic feet. RESEARCH DESIGN AND METHODS: This study was retrospective. A total of 115 patients (140 feet), 107 with acute deformity and 8 with chronic Charcot deformity, were followed for a median of 48 months (range 6-114). The routine treatment for acute cases was a weight-off regimen with crutches and foot protection with therapeutic shoes until skin temperature had normalized followed by increased weightbearing and the use of bespoke shoes or modification of conventional shoes. RESULTS: The incidence of Charcot deformity was 0.3%/year in the diabetic population investigated. About half of the patients were active in their jobs. Major complications were encountered in 5 (4%) of the patients that required surgical intervention: arthrodesis for unstable malaligned ankles in 3 subjects (1 bilaterally) and major amputation in 2 subjects for unstable ankle and pressure sores. Minor complications were recorded in 43% of subjects: new attacks of Charcot breakdown in 41 patients (36%) and/or foot ulceration in 43 patients (37%) that required minor surgical procedures for 11 patients. All healed except in 2 patients: 1 patient died before the Charcot fractures had healed, and 1 patient died with an unhealed ulcer. No patient lost the ability to walk independently. CONCLUSIONS: Major surgical procedures in only 4% were particularly related to patients with Charcot deformities in the ankle. Minor complications were recorded in about half of the patients. Lifelong foot care is required for diabetic patients with Charcot feet.  (+info)

Conventional physiotherapy and treadmill re-training for higher-level gait disorders in cerebrovascular disease. (2/731)

OBJECTIVES: to compare the therapeutic effects of two approaches to gait re-training--a schedule of conventional physiotherapy and treadmill re-training--in patients with higher-level gait disorders associated with cerebral multiinfarct states. DESIGN: single-blind crossover study involving a 4-week baseline period, 4 weeks of treadmill re-training and 4 weeks of conventional physiotherapy. SETTING: a large teaching hospital. SUBJECTS: patients with cerebral multi-infarct states who met the criteria for higher-level gait disorders. Computed tomographic brain scans showed at least one large vessel infarct, basal ganglia and white matter lacunes or extensive leukoaraiosis. INTERVENTIONS: a schedule of treadmill re-training and a specific schedule of physiotherapy containing 31 interventions in three treatment modules: (i) for gait ignition failure and turning; (ii) to improve postural alignment and enhance balance reactions; and (iii) for other components of cerebral multi-infarct state disordered gait. MAIN OUTCOME MEASURES: spatial and temporal gait measures and activity of daily living assessments. RESULTS: we recruited 18 patients, mean (SD) age 79.1 (6.8) years. Patients walked an average of 7.9 (5.5) km on the treadmill and had an average of 6.7 (3.2) h of physiotherapy. There were clinically moderate but highly statistically significant (P < 0.001) improvements in the following indices: time taken to complete the sit-to-stand test; time taken to walk 10 m; number of steps over 10 m; walking velocity; right and left step lengths; and time taken to complete the 'S' test. There were no differences in the results obtained in each limb of the study. CONCLUSION: there is no difference between the effects of conventional physiotherapy and treadmill re-training on the gait of patients with higher-level gait disorders associated with cerebral multi-infarct states. However, the improvements seen during the treatment period suggest that there is scope to improve the gait of this group of frail, elderly patients.  (+info)

Abnormal GABAA receptor-mediated currents in dorsal root ganglion neurons isolated from Na-K-2Cl cotransporter null mice. (3/731)

We have recently disrupted Slc12a2, the gene encoding the secretory Na-K-2Cl cotransporter in mice (NKCC1) (Delpire et al., 1999). Gramicidin perforated-patch and whole-cell recordings were performed to study GABA-induced currents in dorsal root ganglion (DRG) neurons isolated from wild-type and homozygote NKCC1 knock-out mice. In wild-type DRG neurons, strong GABA-evoked inward current was observed at the resting membrane potential, suggesting active accumulation of Cl(-) in these cells. This GABA-induced current was blocked by picrotoxin, a GABA(A) receptor blocker. The strong Cl(-) accumulation that gives rise to depolarizing GABA responses is caused by Na-K-2Cl cotransport because reduction of external Cl(-) or application of bumetanide induced a decrease in [Cl(-)](i), whereas an increase in external K(+) caused an apparent [Cl(-)](i) accumulation. In contrast to control neurons, little or no net current was observed at the resting membrane potential in homozygote NKCC1 mutant DRG neurons. E(GABA) was significantly more negative, demonstrating the absence of Cl(-) accumulation in these cells. Application of bumetanide induced a positive shift of E(GABA), suggesting the presence of an outward Cl(-) transport mechanism. In agreement with an absence of GABA depolarization in DRG neurons, behavioral analysis revealed significant alterations in locomotion and pain perception in the knock-out mouse. Our results clearly demonstrate that the Na-K-2Cl cotransporter is responsible for [Cl(-)](i) accumulation in DRG neurons and that via regulation of intracellular Cl(-), the Na-K-2Cl cotransporter participates in the modulation of GABA neurotransmission and sensory perception.  (+info)

Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions. (4/731)

The dopamine D2 receptor (D2) system has been implicated in several neurological and psychiatric disorders, such as schizophrenia and Parkinson's disease. There are two isoforms of the D2 receptor: the long form (D2L) and the short form (D2S). The two isoforms are generated by alternative splicing of the same gene and differ only by 29 amino acids in their protein structures. Little is known about the distinct functions of either D2 isoform, primarily because selective pharmacological agents are not available. We generated D2L receptor-deficient (D2L-/-) mice by making a subtle mutation in the D2 gene. D2L-/- mice (which still express functional D2S) displayed reduced levels of locomotion and rearing behavior. Interestingly, haloperidol produced significantly less catalepsy and inhibition of locomotor activity in D2L-/- mice. These findings suggest that D2L and D2S may contribute differentially to the regulation of certain motor functions and to the induction of the extrapyramidal side effects associated with the use of typical antipsychotic drugs (e.g., haloperidol). Quinpirole induced a similar initial suppression of locomotor activity in both D2L-/- and wild-type mice. In addition, the D2S receptor in the mutant mice functioned approximately equally well as did D2L as an impulse-modulating autoreceptor. This suggests that the functions of these two isoforms are not dependent on the formation of receptor heterodimers. Our findings may provide novel information for potentially developing improved antipsychotic drugs.  (+info)

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity. (5/731)

Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right and may also serve as a model for studying mechanisms of functional recovery after injury in the CNS. Normal micturition requires coordinated activation of smooth muscle of the bladder (detrusor) and striated muscle of the external urethral sphincter (EUS) that is controlled by spinal and supraspinal circuitry. We used a clinically relevant rat model of thoracic spinal cord contusion injury to examine the effect of varying the degree of residual supraspinal connections on chronic detrusor-EUS coordination. Urodynamic evaluation at 8 weeks after SCI showed that detrusor contractions of the bladder recovered similarly in groups of rats injured with a 10 gm weight dropped 12.5, 25, or 50 mm onto the spinal cord. In contrast, the degree of coordinated activation of the EUS varied with the severity of initial injury and the degree of preservation of white matter at the injury site. The 12.5 mm SCI resulted in the sparing of 20% of the white matter at the injury site and complete recovery of detrusor-EUS coordination. In more severely injured rats, the chronic recovery of detrusor-EUS coordination was very incomplete and correlated to decreased innervation of lower motoneurons by descending control pathways and their increased levels of mRNA for glutamate receptor subunits NR2A and GluR2. These results show that the extent of recovery of detrusor-EUS coordination depends on injury severity and the degree of residual connections with brainstem control centers.  (+info)

Comparative analysis of the gait disorder of normal pressure hydrocephalus and Parkinson's disease. (6/731)

OBJECTIVES: Comparative gait analyses in neurological diseases interfering with locomotion are of particular interest, as many hypokinetic gait disorders have the same main features. The aim of the present study was (1) to compare the gait disturbance in normal pressure hydrocephalus and Parkinson's disease; (2) to evaluate which variables of the disturbed gait pattern respond to specific treatment in both diseases; and (3) to assess the responsiveness to visual and acoustic cues for gait improvement. METHODS: In study 1 gait analysis was carried out on 11 patients with normal pressure hydrocephalus, 10 patients with Parkinson's disease, and 12 age matched healthy control subjects, on a walkway and on a treadmill. In study 2, patients with normal pressure hydrocephalus were reinvestigated after removal of 30 ml CSF, and patients with Parkinson's disease after administration of 150 mg levodopa. In part 3 visual cues were provided as stripes fixed on the walkway and acoustic cues as beats of a metronome. RESULTS: The gait disorder in both diseases shared the feature of a reduced gait velocity, due to a diminished and highly variable stride length. Specific features of the gait disturbance in normal pressure hydrocephalus were a broad based gait pattern with outward rotated feet and a diminished height of the steps. After treatment in both diseases, the speed increased, due to an enlarged stride length, now presenting a lower variability. All other gait variables remained unaffected. External cues only mildly improved gait in normal pressure hydrocephalus, whereas they were highly effective in raising the stride length and cadence in Parkinson's disease. CONCLUSION: The gait pattern in normal pressure hydrocephalus is clearly distinguishable from the gait of Parkinson's disease. As well as the basal ganglia output connections, other pathways and structures most likely in the frontal lobes are responsible for the gait pattern and especially the disturbed dynamic equilibrium in normal pressure hydrocephalus. Hypokinesia and its responsiveness to external cues in both diseases are assumed to be an expression of a disturbed motor planning.  (+info)

Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. (7/731)

To investigate Eph-ephrin bidirectional signaling, a series of mutations were generated in the ephrin-B3 locus. The absence of both forward and reverse signaling resulted in mice with mirror movements as typified by a hopping locomotion. The corticospinal tract was defective as axons failed to respect the midline boundary of the spinal cord and bilaterally innervated both contralateral and ipsilateral motor neuron populations. A second mutation that expresses a truncated ephrin-B3 protein lacking its cytoplasmic domain did not lead to hopping, indicating that reverse signaling is not required for corticospinal innervation. Ephrin-B3 is concentrated at the spinal cord midline, while one of its receptors, EphA4, is expressed in postnatal corticospinal neurons as their fibers pathfind down the contralateral spinal cord. Our data indicate ephrin-B3 functions as a midline-anchored repellent to stimulate forward signaling in EphA4-expressing axons.  (+info)

Modified emory functional ambulation profile: an outcome measure for the rehabilitation of poststroke gait dysfunction. (8/731)

BACKGROUND AND PURPOSE: The modified Emory Functional Ambulation Profile (mEFAP) is an easily administered test that measures the time to ambulate through 5 common environmental terrains with or without an assistive device or manual assistance. The mEFAP was evaluated for its interrater reliability, test-retest reliability, concurrent validity, and sensitivity to change during outpatient rehabilitation for poststroke gait dysfunction. METHODS: Twenty-six poststroke patients were followed up prospectively in a rehabilitation day-treatment program. The mEFAP, Berg Balance Test (BBT), and 7-item mobility subsection of the Functional Independence Measure + Functional Assessment Measure (FAMm) were completed at admission and discharge. RESULTS: mEFAP interrater reliability (intraclass coefficient [ICC] 0.999) and test-retest reliability (ICC 0.998) were high. The BBT demonstrated high interrater (ICC 0.992) but poor test-retest (ICC 0.605) reliability. Initial and final scores comparing the mEFAP with the BBT (r=-0.735, r=-0.703) and the mEFAP with the FAMm (r=0.685, r=-0.775) were strongly correlated. Improvement on the mEFAP correlated with improved BBT performance (r=-0.524). There was no correlation between overall change observed on the FAMm and change on the mEFAP (r=-0.145). Total mEFAP and all mEFAP subtask scores improved over time (P:<0.0001). CONCLUSIONS: The mEFAP is a reliable gait-assessment tool for patients with stroke and is sensitive to change in ambulation speed.  (+info)

A gait disorder is a disturbance in the ability to walk that can't be attributed to physical disabilities such as weakness or paralysis. Neurologic gait disorders are those specifically caused by underlying neurological conditions. These disorders can result from damage to the brain, spinal cord, or peripheral nerves that disrupts communication between the muscles and the brain.

Neurologic gait disorders can present in various ways, including:

1. **Spastic Gait:** This is a stiff, foot-dragging walk caused by increased muscle tone (hypertonia) and stiffness (spasticity). It's often seen in conditions like cerebral palsy or multiple sclerosis.

2. **Ataxic Gait:** This is a broad-based, unsteady, and irregular walk caused by damage to the cerebellum, which affects balance and coordination. Conditions such as cerebellar atrophy or stroke can cause this type of gait disorder.

3. **Parkinsonian Gait:** This is a shuffling walk with small steps, flexed knees, and difficulty turning. It's often seen in Parkinson's disease.

4. **Neuropathic Gait:** This is a high-stepping walk caused by foot drop (difficulty lifting the front part of the foot), which results from damage to the peripheral nerves. Conditions such as diabetic neuropathy or Guillain-Barre syndrome can cause this type of gait disorder.

5. **Choreic Gait:** This is an irregular, dance-like walk caused by involuntary movements (chorea) seen in conditions like Huntington's disease.

6. **Mixed Gait:** Sometimes, a person may exhibit elements of more than one type of gait disorder.

The specific type of gait disorder can provide important clues about the underlying neurological condition and help guide diagnosis and treatment.

Gait is a medical term used to describe the pattern of movement of the limbs during walking or running. It includes the manner or style of walking, including factors such as rhythm, speed, and step length. A person's gait can provide important clues about their physical health and neurological function, and abnormalities in gait may indicate the presence of underlying medical conditions, such as neuromuscular disorders, orthopedic problems, or injuries.

A typical human gait cycle involves two main phases: the stance phase, during which the foot is in contact with the ground, and the swing phase, during which the foot is lifted and moved forward in preparation for the next step. The gait cycle can be further broken down into several sub-phases, including heel strike, foot flat, midstance, heel off, and toe off.

Gait analysis is a specialized field of study that involves observing and measuring a person's gait pattern using various techniques, such as video recordings, force plates, and motion capture systems. This information can be used to diagnose and treat gait abnormalities, improve mobility and function, and prevent injuries.

Gait apraxia is a neurological disorder that affects an individual's ability to perform coordinated and complex movements required for walking, despite having the physical capability to do so. It is not caused by weakness or sensory loss, but rather by damage to the brain areas responsible for motor planning and execution, particularly in the frontal lobes.

Gait apraxia is characterized by a wide-based, hesitant, and unsteady gait pattern. Individuals with this condition may have difficulty initiating walking, changing direction, or adjusting their stride length and speed. They may also exhibit symptoms such as freezing of gait, where they are unable to move their feet forward despite intending to walk.

This disorder is often associated with various neurological conditions, including cerebrovascular accidents (strokes), degenerative diseases such as Parkinson's disease and multiple sclerosis, traumatic brain injuries, and infections of the central nervous system. Treatment typically involves physical therapy, gait training, and the use of assistive devices to improve mobility and safety.

I'm sorry for any confusion, but "Office Management" is not a medical term. It refers to the administrative and operational functions of an office or organization, including tasks such as coordinating staff, overseeing budgets and expenses, maintaining records, and ensuring efficient workflow. However, in a medical setting, office management responsibilities may include scheduling appointments, managing patient records, handling insurance claims, and communicating with patients and healthcare providers.

Higher Nervous Activity (HNA) is a term used in neurology and psychology to refer to the complex functions of the nervous system that are associated with higher order cognitive processes, such as thinking, learning, memory, perception, and language. These functions are primarily mediated by the cerebral cortex and other associative areas of the brain, which are involved in integrating sensory information, planning and executing motor responses, and modulating emotional and social behavior.

HNA is often contrasted with lower nervous activity (LNA), which refers to more basic functions of the nervous system, such as reflexes and automatic responses that do not require conscious control or higher-order cognitive processing. HNA is thought to be unique to humans and some other animals, and is believed to have evolved to enable complex behaviors and adaptations to changing environments.

Disorders of HNA can result in a wide range of neurological and psychiatric symptoms, depending on the specific areas of the brain that are affected. These may include cognitive impairments, memory loss, language disorders, perceptual disturbances, emotional dysregulation, and motor deficits.

Ideomotor apraxia is a neurological disorder that affects the ability to perform learned, purposeful movements in the absence of muscle weakness or paralysis. It results from damage to specific areas of the brain that are responsible for motor planning and execution.

In ideomotor apraxia, the person has difficulty translating an intention or idea into the appropriate movement. For example, if asked to pantomime using a toothbrush, they may not be able to recall and execute the correct sequence of movements required for this task, even though they understand what is being asked of them and have no problem moving their arm or hand.

This disorder can manifest as awkward, poorly coordinated, or incomplete movements, often with inconsistent errors. Ideomotor apraxia is typically seen following lesions to the left hemisphere of the brain, particularly in regions associated with language and motor function, such as Broca's area and the parietal lobe. Treatment usually involves occupational therapy and strategies to help compensate for the impaired motor skills.

Movement disorders are a group of neurological conditions that affect the control and coordination of voluntary movements. These disorders can result from damage to or dysfunction of the cerebellum, basal ganglia, or other parts of the brain that regulate movement. Symptoms may include tremors, rigidity, bradykinesia (slowness of movement), akathisia (restlessness and inability to remain still), dystonia (sustained muscle contractions leading to abnormal postures), chorea (rapid, unpredictable movements), tics, and gait disturbances. Examples of movement disorders include Parkinson's disease, Huntington's disease, Tourette syndrome, and dystonic disorders.

The Pedunculopontine Tegmental Nucleus (PPN) is a group of neurons located in the brainstem, specifically in the rostral pons and caudal mesencephalon. It plays a crucial role in various functions such as sleep-wake regulation, motor control, reward processing, and attention.

The PPN can be further divided into two subregions: the pedunculopontine tegmental nucleus pars oralis (PPTg) and the pedunculopontine tegmental nucleus pars caudalis (PPTc). These subregions contain cholinergic, glutamatergic, and GABAergic neurons that project to various brain regions, including the thalamus, basal forebrain, and cerebral cortex.

Dysfunction of the PPN has been implicated in several neurological disorders, such as Parkinson's disease, REM sleep behavior disorder, and depression. Therefore, understanding the structure and function of the PPN is essential for developing potential therapeutic strategies for these conditions.

Lameness in animals refers to an alteration in the animal's normal gait or movement, which is often caused by pain, injury, or disease affecting the locomotor system. This can include structures such as bones, joints, muscles, tendons, and ligaments. The severity of lameness can vary from subtle to non-weight bearing, and it can affect one or more limbs.

Lameness can have various causes, including trauma, infection, degenerative diseases, congenital defects, and neurological disorders. In order to diagnose and treat lameness in animals, a veterinarian will typically perform a physical examination, observe the animal's gait and movement, and may use diagnostic imaging techniques such as X-rays or ultrasound to identify the underlying cause. Treatment for lameness can include medication, rest, physical therapy, surgery, or a combination of these approaches.

A neurological examination is a series of tests used to evaluate the functioning of the nervous system, including both the central nervous system (the brain and spinal cord) and peripheral nervous system (the nerves that extend from the brain and spinal cord to the rest of the body). It is typically performed by a healthcare professional such as a neurologist or a primary care physician with specialized training in neurology.

During a neurological examination, the healthcare provider will assess various aspects of neurological function, including:

1. Mental status: This involves evaluating a person's level of consciousness, orientation, memory, and cognitive abilities.
2. Cranial nerves: There are 12 cranial nerves that control functions such as vision, hearing, smell, taste, and movement of the face and neck. The healthcare provider will test each of these nerves to ensure they are functioning properly.
3. Motor function: This involves assessing muscle strength, tone, coordination, and reflexes. The healthcare provider may ask the person to perform certain movements or tasks to evaluate these functions.
4. Sensory function: The healthcare provider will test a person's ability to feel different types of sensations, such as touch, pain, temperature, vibration, and proprioception (the sense of where your body is in space).
5. Coordination and balance: The healthcare provider may assess a person's ability to perform coordinated movements, such as touching their finger to their nose or walking heel-to-toe.
6. Reflexes: The healthcare provider will test various reflexes throughout the body using a reflex hammer.

The results of a neurological examination can help healthcare providers diagnose and monitor conditions that affect the nervous system, such as stroke, multiple sclerosis, Parkinson's disease, or peripheral neuropathy.

Medical science often defines and describes "walking" as a form of locomotion or mobility where an individual repeatedly lifts and sets down each foot to move forward, usually bearing weight on both legs. It is a complex motor activity that requires the integration and coordination of various systems in the human body, including the musculoskeletal, neurological, and cardiovascular systems.

Walking involves several components such as balance, coordination, strength, and endurance. The ability to walk independently is often used as a measure of functional mobility and overall health status. However, it's important to note that the specific definition of walking may vary depending on the context and the medical or scientific field in question.

Postural balance is the ability to maintain, achieve, or restore a state of equilibrium during any posture or activity. It involves the integration of sensory information (visual, vestibular, and proprioceptive) to control and adjust body position in space, thereby maintaining the center of gravity within the base of support. This is crucial for performing daily activities and preventing falls, especially in older adults and individuals with neurological or orthopedic conditions.

Parkinson's disease is a progressive neurodegenerative disorder that affects movement. It is characterized by the death of dopamine-producing cells in the brain, specifically in an area called the substantia nigra. The loss of these cells leads to a decrease in dopamine levels, which results in the motor symptoms associated with Parkinson's disease. These symptoms can include tremors at rest, stiffness or rigidity of the limbs and trunk, bradykinesia (slowness of movement), and postural instability (impaired balance and coordination). In addition to these motor symptoms, non-motor symptoms such as cognitive impairment, depression, anxiety, and sleep disturbances are also common in people with Parkinson's disease. The exact cause of Parkinson's disease is unknown, but it is thought to be a combination of genetic and environmental factors. There is currently no cure for Parkinson's disease, but medications and therapies can help manage the symptoms and improve quality of life.

A geriatric assessment is a comprehensive, multidimensional evaluation of an older adult's functional ability, mental health, social support, and overall health status. It is used to identify any medical, psychological, or social problems that could affect the person's ability to live independently and safely, and to develop an individualized plan of care to address those issues.

The assessment typically includes a review of the person's medical history, medications, cognitive function, mobility, sensory function, nutrition, continence, and mood. It may also include assessments of the person's social support network, living situation, and financial resources. The goal of the geriatric assessment is to help older adults maintain their independence and quality of life for as long as possible by addressing any issues that could put them at risk for disability or institutionalization.

Gait ataxia is a type of ataxia, which refers to a lack of coordination or stability, specifically involving walking or gait. It is characterized by an unsteady, uncoordinated, and typically wide-based gait pattern. This occurs due to dysfunction in the cerebellum or its connecting pathways, responsible for maintaining balance and coordinating muscle movements.

In gait ataxia, individuals often have difficulty with controlling the rhythm and pace of their steps, tend to veer or stagger off course, and may display a reeling or stumbling motion while walking. They might also have trouble performing rapid alternating movements like quickly tapping their foot or heel. These symptoms are usually worse when the person is tired or attempting to walk in the dark.

Gait ataxia can be caused by various underlying conditions, including degenerative neurological disorders (e.g., cerebellar atrophy, multiple sclerosis), stroke, brain injury, infection (e.g., alcoholism, HIV), or exposure to certain toxins. Proper diagnosis and identification of the underlying cause are essential for effective treatment and management of gait ataxia.

Nervous system diseases, also known as neurological disorders, refer to a group of conditions that affect the nervous system, which includes the brain, spinal cord, nerves, and muscles. These diseases can affect various functions of the body, such as movement, sensation, cognition, and behavior. They can be caused by genetics, infections, injuries, degeneration, or tumors. Examples of nervous system diseases include Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy, migraine, stroke, and neuroinfections like meningitis and encephalitis. The symptoms and severity of these disorders can vary widely, ranging from mild to severe and debilitating.

Bipolar disorder, also known as manic-depressive illness, is a mental health condition that causes extreme mood swings that include emotional highs (mania or hypomania) and lows (depression). When you become depressed, you may feel sad or hopeless and lose interest or pleasure in most activities. When your mood shifts to mania or hypomania (a less severe form of mania), you may feel euphoric, full of energy, or unusually irritable. These mood swings can significantly affect your job, school, relationships, and overall quality of life.

Bipolar disorder is typically characterized by the presence of one or more manic or hypomanic episodes, often accompanied by depressive episodes. The episodes may be separated by periods of normal mood, but in some cases, a person may experience rapid cycling between mania and depression.

There are several types of bipolar disorder, including:

* Bipolar I Disorder: This type is characterized by the occurrence of at least one manic episode, which may be preceded or followed by hypomanic or major depressive episodes.
* Bipolar II Disorder: This type involves the presence of at least one major depressive episode and at least one hypomanic episode, but no manic episodes.
* Cyclothymic Disorder: This type is characterized by numerous periods of hypomania and depression that are not severe enough to meet the criteria for a full manic or depressive episode.
* Other Specified and Unspecified Bipolar and Related Disorders: These categories include bipolar disorders that do not fit the criteria for any of the other types.

The exact cause of bipolar disorder is unknown, but it appears to be related to a combination of genetic, environmental, and neurochemical factors. Treatment typically involves a combination of medication, psychotherapy, and lifestyle changes to help manage symptoms and prevent relapses.

A mental disorder is a syndrome characterized by clinically significant disturbance in an individual's cognition, emotion regulation, or behavior. It's associated with distress and/or impaired functioning in social, occupational, or other important areas of life, often leading to a decrease in quality of life. These disorders are typically persistent and can be severe and disabling. They may be related to factors such as genetics, early childhood experiences, or trauma. Examples include depression, anxiety disorders, bipolar disorder, schizophrenia, and personality disorders. It's important to note that a diagnosis should be made by a qualified mental health professional.

Anxiety disorders are a category of mental health disorders characterized by feelings of excessive and persistent worry, fear, or anxiety that interfere with daily activities. They include several different types of disorders, such as:

1. Generalized Anxiety Disorder (GAD): This is characterized by chronic and exaggerated worry and tension, even when there is little or nothing to provoke it.
2. Panic Disorder: This is characterized by recurring unexpected panic attacks and fear of experiencing more panic attacks.
3. Social Anxiety Disorder (SAD): Also known as social phobia, this is characterized by excessive fear, anxiety, or avoidance of social situations due to feelings of embarrassment, self-consciousness, and concern about being judged or viewed negatively by others.
4. Phobias: These are intense, irrational fears of certain objects, places, or situations. When a person with a phobia encounters the object or situation they fear, they may experience panic attacks or other severe anxiety responses.
5. Agoraphobia: This is a fear of being in places where it may be difficult to escape or get help if one has a panic attack or other embarrassing or incapacitating symptoms.
6. Separation Anxiety Disorder (SAD): This is characterized by excessive anxiety about separation from home or from people to whom the individual has a strong emotional attachment (such as a parent, sibling, or partner).
7. Selective Mutism: This is a disorder where a child becomes mute in certain situations, such as at school, but can speak normally at home or with close family members.

These disorders are treatable with a combination of medication and psychotherapy (cognitive-behavioral therapy, exposure therapy). It's important to seek professional help if you suspect that you or someone you know may have an anxiety disorder.

Mood disorders are a category of mental health disorders characterized by significant and persistent changes in mood, affect, and emotional state. These disorders can cause disturbances in normal functioning and significantly impair an individual's ability to carry out their daily activities. The two primary types of mood disorders are depressive disorders (such as major depressive disorder or persistent depressive disorder) and bipolar disorders (which include bipolar I disorder, bipolar II disorder, and cyclothymic disorder).

Depressive disorders involve prolonged periods of low mood, sadness, hopelessness, and a lack of interest in activities. Individuals with these disorders may also experience changes in sleep patterns, appetite, energy levels, concentration, and self-esteem. In severe cases, they might have thoughts of death or suicide.

Bipolar disorders involve alternating episodes of mania (or hypomania) and depression. During a manic episode, individuals may feel extremely elated, energetic, or irritable, with racing thoughts, rapid speech, and impulsive behavior. They might engage in risky activities, have decreased sleep needs, and display poor judgment. In contrast, depressive episodes involve the same symptoms as depressive disorders.

Mood disorders can be caused by a combination of genetic, biological, environmental, and psychological factors. Proper diagnosis and treatment, which may include psychotherapy, medication, or a combination of both, are essential for managing these conditions and improving quality of life.

Biomechanics is the application of mechanical laws to living structures and systems, particularly in the field of medicine and healthcare. A biomechanical phenomenon refers to a observable event or occurrence that involves the interaction of biological tissues or systems with mechanical forces. These phenomena can be studied at various levels, from the molecular and cellular level to the tissue, organ, and whole-body level.

Examples of biomechanical phenomena include:

1. The way that bones and muscles work together to produce movement (known as joint kinematics).
2. The mechanical behavior of biological tissues such as bone, cartilage, tendons, and ligaments under various loads and stresses.
3. The response of cells and tissues to mechanical stimuli, such as the way that bone tissue adapts to changes in loading conditions (known as Wolff's law).
4. The biomechanics of injury and disease processes, such as the mechanisms of joint injury or the development of osteoarthritis.
5. The use of mechanical devices and interventions to treat medical conditions, such as orthopedic implants or assistive devices for mobility impairments.

Understanding biomechanical phenomena is essential for developing effective treatments and prevention strategies for a wide range of medical conditions, from musculoskeletal injuries to neurological disorders.

The Diagnostic and Statistical Manual of Mental Disorders (DSM) is a publication of the American Psychiatric Association (APA) that provides diagnostic criteria for mental disorders. It is widely used by mental health professionals in the United States and around the world to diagnose and classify mental health conditions.

The DSM includes detailed descriptions of symptoms, clinical examples, and specific criteria for each disorder, which are intended to facilitate accurate diagnosis and improve communication among mental health professionals. The manual is regularly updated to reflect current research and clinical practice, with the most recent edition being the DSM-5, published in 2013.

It's important to note that while the DSM is a valuable tool for mental health professionals, it is not without controversy. Some critics argue that the manual medicalizes normal human experiences and that its categories may be too broad or overlapping. Nonetheless, it remains an essential resource for clinicians, researchers, and policymakers in the field of mental health.

Major Depressive Disorder (MDD), also simply referred to as depression, is a serious mental health condition characterized by the presence of one or more major depressive episodes. A major depressive episode is a period of at least two weeks during which an individual experiences a severely depressed mood and/or loss of interest or pleasure in nearly all activities, accompanied by at least four additional symptoms such as significant changes in appetite or weight, sleep disturbances, psychomotor agitation or retardation, fatigue or loss of energy, feelings of worthlessness or excessive guilt, difficulty thinking, concentrating, or making decisions, and recurrent thoughts of death or suicide.

MDD can significantly impair an individual's ability to function in daily life, and it is associated with increased risks of suicide, substance abuse, and other mental health disorders. The exact cause of MDD is not fully understood, but it is believed to result from a complex interplay of genetic, biological, environmental, and psychological factors. Treatment typically involves a combination of psychotherapy (such as cognitive-behavioral therapy) and medication (such as selective serotonin reuptake inhibitors or tricyclic antidepressants).

Attention Deficit Hyperactivity Disorder (ADHD) with hyperactivity is a neurodevelopmental disorder that affects both children and adults. The condition is characterized by symptoms including:

1. Difficulty paying attention or staying focused on a single task
2. Impulsivity, or acting without thinking
3. Hyperactivity, or excessive fidgeting, restlessness, or talking

In order to be diagnosed with ADHD with hyperactivity, an individual must exhibit these symptoms to a degree that is developmentally inappropriate and interferes with their daily functioning. Additionally, the symptoms must have been present for at least six months and be present in multiple settings (e.g., at home, school, work).

It's important to note that ADHD can manifest differently in different people, and some individuals may experience predominantly inattentive or impulsive symptoms rather than hyperactive ones. However, when the hyperactive component is prominent, it is referred to as ADHD with hyperactivity.

Effective treatments for ADHD with hyperactivity include a combination of medication (such as stimulants) and behavioral therapy. With appropriate treatment, individuals with ADHD can learn to manage their symptoms and lead successful, fulfilling lives.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

A depressive disorder is a mental health condition characterized by persistent feelings of sadness, hopelessness, and loss of interest or pleasure in activities. It can also include changes in sleep, appetite, energy levels, concentration, and self-esteem, as well as thoughts of death or suicide. Depressive disorders can vary in severity and duration, with some people experiencing mild and occasional symptoms, while others may have severe and chronic symptoms that interfere with their ability to function in daily life.

There are several types of depressive disorders, including major depressive disorder (MDD), persistent depressive disorder (PDD), and postpartum depression. MDD is characterized by symptoms that interfere significantly with a person's ability to function and last for at least two weeks, while PDD involves chronic low-grade depression that lasts for two years or more. Postpartum depression occurs in women after childbirth and can range from mild to severe.

Depressive disorders are thought to be caused by a combination of genetic, biological, environmental, and psychological factors. Treatment typically involves a combination of medication, psychotherapy (talk therapy), and lifestyle changes.

Autistic Disorder, also known as Autism or Classic Autism, is a neurodevelopmental disorder that affects communication and behavior. It is characterized by:

1. Persistent deficits in social communication and social interaction across multiple contexts, including:
* Deficits in social-emotional reciprocity;
* Deficits in nonverbal communicative behaviors used for social interaction;
* Deficits in developing, maintaining, and understanding relationships.
2. Restricted, repetitive patterns of behavior, interests, or activities, as manifested by at least two of the following:
* Stereotyped or repetitive motor movements, use of objects, or speech;
* Insistence on sameness, inflexible adherence to routines, or ritualized patterns of verbal or nonverbal behavior;
* Highly restricted, fixated interests that are abnormal in intensity or focus;
* Hyper- or hyporeactivity to sensory input or unusual interest in sensory aspects of the environment.
3. Symptoms must be present in the early developmental period (but may not become fully manifest until social demands exceed limited capacities) and limit or impair everyday functioning.
4. Symptoms do not occur exclusively during the course of a schizophrenia spectrum disorder or other psychotic disorders.

Autistic Disorder is part of the autism spectrum disorders (ASDs), which also include Asperger's Syndrome and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS). The current diagnostic term for this category of conditions, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), is Autism Spectrum Disorder.

Obsessive-Compulsive Disorder (OCD) is a mental health disorder characterized by the presence of obsessions and compulsions. Obsessions are recurrent and persistent thoughts, urges, or images that are intrusive, unwanted, and often distressing. Compulsions are repetitive behaviors or mental acts that an individual feels driven to perform in response to an obsession or according to rigid rules, and which are aimed at preventing or reducing anxiety or distress, or preventing some dreaded event or situation. These obsessions and/or compulsions cause significant distress, take up a lot of time (an hour or more a day), and interfere with the individual's daily life, including social activities, relationships, and work or school performance. OCD is considered a type of anxiety disorder and can also co-occur with other mental health conditions.

Post-traumatic stress disorder (PTSD) is a psychiatric condition that can occur in people who have experienced or witnessed a traumatic event such as a natural disaster, serious accident, war combat, rape, or violent personal assault. According to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5), PTSD is characterized by the following symptoms, which must last for more than one month:

1. Intrusion symptoms: These include distressing memories, nightmares, flashbacks, or intense psychological distress or reactivity to internal or external cues that symbolize or resemble an aspect of the traumatic event.
2. Avoidance symptoms: Persistent avoidance of stimuli associated with the traumatic event, including thoughts, feelings, conversations, activities, places, or people.
3. Negative alterations in cognitions and mood: This includes negative beliefs about oneself, others, or the world; distorted blame of self or others for causing the trauma; persistent negative emotional state; decreased interest in significant activities; and feelings of detachment or estrangement from others.
4. Alterations in arousal and reactivity: This includes irritable behavior and angry outbursts, reckless or self-destructive behavior, hypervigilance, exaggerated startle response, problems with concentration, and sleep disturbance.
5. Duration of symptoms: The symptoms must last for more than one month.
6. Functional significance: The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

It is essential to note that PTSD can occur at any age and can be accompanied by various physical and mental health problems, such as depression, substance abuse, memory problems, and other difficulties in cognition. Appropriate treatment, which may include psychotherapy, medication, or a combination of both, can significantly improve the symptoms and overall quality of life for individuals with PTSD.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Orthotic devices are custom-made or prefabricated appliances designed to align, support, prevent deformity, or improve the function of movable body parts. They are frequently used in the treatment of various musculoskeletal disorders, such as foot and ankle conditions, knee problems, spinal alignment issues, and hand or wrist ailments. These devices can be adjustable or non-adjustable and are typically made from materials like plastic, metal, leather, or fabric. They work by redistributing forces across joints, correcting alignment, preventing unwanted movements, or accommodating existing deformities. Examples of orthotic devices include ankle-foot orthoses, knee braces, back braces, wrist splints, and custom-made foot insoles.

Treatment outcome is a term used to describe the result or effect of medical treatment on a patient's health status. It can be measured in various ways, such as through symptoms improvement, disease remission, reduced disability, improved quality of life, or survival rates. The treatment outcome helps healthcare providers evaluate the effectiveness of a particular treatment plan and make informed decisions about future care. It is also used in clinical research to compare the efficacy of different treatments and improve patient care.

A phobic disorder is a type of anxiety disorder characterized by an excessive and irrational fear or avoidance of specific objects, situations, or activities. This fear can cause significant distress and interfere with a person's daily life. Phobic disorders are typically classified into three main categories: specific phobias (such as fear of heights, spiders, or needles), social phobia (or social anxiety disorder), and agoraphobia (fear of open spaces or situations where escape might be difficult).

People with phobic disorders often recognize that their fear is excessive or unreasonable, but they are unable to control it. When exposed to the feared object or situation, they may experience symptoms such as rapid heartbeat, sweating, trembling, and difficulty breathing. These symptoms can be so distressing that individuals with phobic disorders go to great lengths to avoid the feared situation, which can have a significant impact on their quality of life.

Treatment for phobic disorders typically involves cognitive-behavioral therapy (CBT), which helps individuals identify and challenge their irrational thoughts and fears, as well as exposure therapy, which gradually exposes them to the feared object or situation in a safe and controlled environment. In some cases, medication may also be recommended to help manage symptoms of anxiety.

Pervasive developmental disorders (PDD) are a group of conditions that affect the development and functioning of the brain, leading to delays in many areas of development. The American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) has replaced the term "pervasive developmental disorders" with "autism spectrum disorder" and "other neurodevelopmental disorders."

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and interaction across multiple contexts, as well as restricted, repetitive patterns of behavior, interests, or activities. The symptoms of ASD can range from mild to severe, and the condition affects approximately 1 in 54 children in the United States.

Other neurodevelopmental disorders that were previously classified as PDDs include:

1. Intellectual disability (ID): a condition characterized by significant limitations in intellectual functioning and adaptive behavior, which covers many everyday social and practical skills. This disorder used to be referred to as "mental retardation."
2. Communication disorders: these are disorders that affect an individual's ability to communicate, including language disorders, speech sound disorders, and stuttering.
3. Attention-deficit/hyperactivity disorder (ADHD): a neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity.
4. Specific learning disorder: a neurodevelopmental disorder that affects an individual's ability to learn and use specific academic skills, such as reading, writing, or mathematics.
5. Motor disorders: these are disorders that affect an individual's movement and coordination, including developmental coordination disorder, stereotypic movement disorder, and tic disorders.

The medical definition of 'Child Development Disorders, Pervasive' has been replaced with more specific diagnoses in the DSM-5 to better reflect the diverse nature of these conditions and improve diagnostic accuracy and treatment planning.

Psychotic disorders are a group of severe mental health conditions characterized by distorted perceptions, thoughts, and emotions that lead to an inability to recognize reality. The two most common symptoms of psychotic disorders are hallucinations and delusions. Hallucinations are when a person sees, hears, or feels things that aren't there, while delusions are fixed, false beliefs that are not based on reality.

Other symptoms may include disorganized speech, disorganized behavior, catatonic behavior, and negative symptoms such as apathy and lack of emotional expression. Schizophrenia is the most well-known psychotic disorder, but other types include schizoaffective disorder, delusional disorder, brief psychotic disorder, shared psychotic disorder, and substance-induced psychotic disorder.

Psychotic disorders can be caused by a variety of factors, including genetics, brain chemistry imbalances, trauma, and substance abuse. Treatment typically involves a combination of medication, therapy, and support services to help manage symptoms and improve quality of life.

Cognitive disorders are a category of mental health disorders that primarily affect cognitive abilities including learning, memory, perception, and problem-solving. These disorders can be caused by various factors such as brain injury, degenerative diseases, infection, substance abuse, or developmental disabilities. Examples of cognitive disorders include dementia, amnesia, delirium, and intellectual disability. It's important to note that the specific definition and diagnostic criteria for cognitive disorders may vary depending on the medical source or classification system being used.

Substance-related disorders, as defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), refer to a group of conditions caused by the use of substances such as alcohol, drugs, or medicines. These disorders are characterized by a problematic pattern of using a substance that leads to clinically significant impairment or distress. They can be divided into two main categories: substance use disorders and substance-induced disorders. Substance use disorders involve a pattern of compulsive use despite negative consequences, while substance-induced disorders include conditions such as intoxication, withdrawal, and substance/medication-induced mental disorders. The specific diagnosis depends on the type of substance involved, the patterns of use, and the presence or absence of physiological dependence.

Paresis is a medical term that refers to a partial loss of voluntary muscle function. It is often described as muscle weakness, and it can affect one or several parts of the body. Paresis can be caused by various conditions, including nerve damage, stroke, spinal cord injuries, multiple sclerosis, and infections like polio or botulism. The severity of paresis can range from mild to severe, depending on the underlying cause and the specific muscles involved. Treatment for paresis typically focuses on addressing the underlying condition causing it.

The ankle joint, also known as the talocrural joint, is the articulation between the bones of the lower leg (tibia and fibula) and the talus bone in the foot. It is a synovial hinge joint that allows for dorsiflexion and plantarflexion movements, which are essential for walking, running, and jumping. The ankle joint is reinforced by strong ligaments on both sides to provide stability during these movements.

Locomotion, in a medical context, refers to the ability to move independently and change location. It involves the coordinated movement of the muscles, bones, and nervous system that enables an individual to move from one place to another. This can include walking, running, jumping, or using assistive devices such as wheelchairs or crutches. Locomotion is a fundamental aspect of human mobility and is often assessed in medical evaluations to determine overall health and functioning.

In medical terms, the foot is the part of the lower limb that is distal to the leg and below the ankle, extending from the tarsus to the toes. It is primarily responsible for supporting body weight and facilitating movement through push-off during walking or running. The foot is a complex structure made up of 26 bones, 33 joints, and numerous muscles, tendons, ligaments, and nerves that work together to provide stability, balance, and flexibility. It can be divided into three main parts: the hindfoot, which contains the talus and calcaneus (heel) bones; the midfoot, which includes the navicular, cuboid, and cuneiform bones; and the forefoot, which consists of the metatarsals and phalanges that form the toes.

Hemiplegia is a medical term that refers to paralysis affecting one side of the body. It is typically caused by damage to the motor center of the brain, such as from a stroke, head injury, or brain tumor. The symptoms can vary in severity but often include muscle weakness, stiffness, and difficulty with coordination and balance on the affected side. In severe cases, the individual may be unable to move or feel anything on that side of the body. Hemiplegia can also affect speech, vision, and other functions controlled by the damaged area of the brain. Rehabilitation therapy is often recommended to help individuals with hemiplegia regain as much function as possible.

"Walker" is not a medical term per se, but it is often used in the medical field to refer to a mobility aid that helps individuals who have difficulty walking independently. Walkers are typically made of lightweight metal and have four legs that provide stability and support. Some walkers come with wheels or glides on the front legs to make it easier for users to move around. They may also include brakes, seats, and baskets for added functionality.

Walkers can be beneficial for people who have mobility limitations due to various medical conditions such as arthritis, stroke, fractures, neurological disorders, or aging-related issues. Using a walker can help reduce the risk of falls, improve balance, increase independence, and enhance overall quality of life.

It is essential to consult with a healthcare professional before using a walker to ensure proper fit, adjustment, and usage techniques for maximum safety and effectiveness.

Central nervous system (CNS) diseases refer to medical conditions that primarily affect the brain and spinal cord. The CNS is responsible for controlling various functions in the body, including movement, sensation, cognition, and behavior. Therefore, diseases of the CNS can have significant impacts on a person's quality of life and overall health.

There are many different types of CNS diseases, including:

1. Infectious diseases: These are caused by viruses, bacteria, fungi, or parasites that infect the brain or spinal cord. Examples include meningitis, encephalitis, and polio.
2. Neurodegenerative diseases: These are characterized by progressive loss of nerve cells in the brain or spinal cord. Examples include Alzheimer's disease, Parkinson's disease, and Huntington's disease.
3. Structural diseases: These involve damage to the physical structure of the brain or spinal cord, such as from trauma, tumors, or stroke.
4. Functional diseases: These affect the function of the nervous system without obvious structural damage, such as multiple sclerosis and epilepsy.
5. Genetic disorders: Some CNS diseases are caused by genetic mutations, such as spinal muscular atrophy and Friedreich's ataxia.

Symptoms of CNS diseases can vary widely depending on the specific condition and the area of the brain or spinal cord that is affected. They may include muscle weakness, paralysis, seizures, loss of sensation, difficulty with coordination and balance, confusion, memory loss, changes in behavior or mood, and pain. Treatment for CNS diseases depends on the specific condition and may involve medications, surgery, rehabilitation therapy, or a combination of these approaches.

In the field of medicine, "time factors" refer to the duration of symptoms or time elapsed since the onset of a medical condition, which can have significant implications for diagnosis and treatment. Understanding time factors is crucial in determining the progression of a disease, evaluating the effectiveness of treatments, and making critical decisions regarding patient care.

For example, in stroke management, "time is brain," meaning that rapid intervention within a specific time frame (usually within 4.5 hours) is essential to administering tissue plasminogen activator (tPA), a clot-busting drug that can minimize brain damage and improve patient outcomes. Similarly, in trauma care, the "golden hour" concept emphasizes the importance of providing definitive care within the first 60 minutes after injury to increase survival rates and reduce morbidity.

Time factors also play a role in monitoring the progression of chronic conditions like diabetes or heart disease, where regular follow-ups and assessments help determine appropriate treatment adjustments and prevent complications. In infectious diseases, time factors are crucial for initiating antibiotic therapy and identifying potential outbreaks to control their spread.

Overall, "time factors" encompass the significance of recognizing and acting promptly in various medical scenarios to optimize patient outcomes and provide effective care.

Ataxia is a medical term that refers to a group of disorders affecting coordination, balance, and speech. It is characterized by a lack of muscle control during voluntary movements, causing unsteady or awkward movements, and often accompanied by tremors. Ataxia can affect various parts of the body, such as the limbs, trunk, eyes, and speech muscles. The condition can be congenital or acquired, and it can result from damage to the cerebellum, spinal cord, or sensory nerves. There are several types of ataxia, including hereditary ataxias, degenerative ataxias, cerebellar ataxias, and acquired ataxias, each with its own specific causes, symptoms, and prognosis. Treatment for ataxia typically focuses on managing symptoms and improving quality of life, as there is no cure for most forms of the disorder.

Conduct Disorder is a mental health disorder that typically begins in childhood or adolescence and is characterized by a repetitive pattern of behavior that violates the rights of others or major age-appropriate societal norms and rules. The behaviors fall into four main categories: aggression to people and animals, destruction of property, deceitfulness or theft, and serious violation of rules.

The specific symptoms of Conduct Disorder can vary widely among individuals, but they generally include:

1. Aggression to people and animals: This may include physical fights, bullying, threatening others, cruelty to animals, and use of weapons.
2. Destruction of property: This may include deliberate destruction of others' property, arson, and vandalism.
3. Deceitfulness or theft: This may include lying, shoplifting, stealing, and breaking into homes, buildings, or cars.
4. Serious violation of rules: This may include running away from home, truancy, staying out late without permission, and frequent violations of school rules.

Conduct Disorder can have serious consequences for individuals who suffer from it, including academic failure, substance abuse, depression, anxiety, and difficulties in interpersonal relationships. It is important to note that Conduct Disorder should be diagnosed by a qualified mental health professional based on a comprehensive evaluation.

An accidental fall is an unplanned, unexpected event in which a person suddenly and involuntarily comes to rest on the ground or other lower level, excluding intentional changes in position (e.g., jumping to catch a ball) and landings that are part of a planned activity (e.g., diving into a pool). Accidental falls can occur for various reasons, such as environmental hazards, muscle weakness, balance problems, visual impairment, or certain medical conditions. They are a significant health concern, particularly among older adults, as they can lead to serious injuries, loss of independence, reduced quality of life, and increased mortality.

Cerebral palsy (CP) is a group of disorders that affect a person's ability to move and maintain balance and posture. According to the Mayo Clinic, CP is caused by abnormal brain development or damage to the developing brain that affects a child's ability to control movement.

The symptoms of cerebral palsy can vary in severity and may include:

* Spasticity (stiff or tight muscles)
* Rigidity (resistance to passive movement)
* Poor coordination and balance
* Weakness or paralysis
* Tremors or involuntary movements
* Abnormal gait or difficulty walking
* Difficulty with fine motor skills, such as writing or using utensils
* Speech and language difficulties
* Vision, hearing, or swallowing problems

It's important to note that cerebral palsy is not a progressive condition, meaning that it does not worsen over time. However, the symptoms may change over time, and some individuals with CP may experience additional medical conditions as they age.

Cerebral palsy is usually caused by brain damage that occurs before or during birth, but it can also be caused by brain injuries that occur in the first few years of life. Some possible causes of cerebral palsy include:

* Infections during pregnancy
* Lack of oxygen to the brain during delivery
* Traumatic head injury during birth
* Brain bleeding or stroke in the newborn period
* Genetic disorders
* Maternal illness or infection during pregnancy

There is no cure for cerebral palsy, but early intervention and treatment can help improve outcomes and quality of life. Treatment may include physical therapy, occupational therapy, speech therapy, medications to manage symptoms, surgery, and assistive devices such as braces or wheelchairs.

A Severity of Illness Index is a measurement tool used in healthcare to assess the severity of a patient's condition and the risk of mortality or other adverse outcomes. These indices typically take into account various physiological and clinical variables, such as vital signs, laboratory values, and co-morbidities, to generate a score that reflects the patient's overall illness severity.

Examples of Severity of Illness Indices include the Acute Physiology and Chronic Health Evaluation (APACHE) system, the Simplified Acute Physiology Score (SAPS), and the Mortality Probability Model (MPM). These indices are often used in critical care settings to guide clinical decision-making, inform prognosis, and compare outcomes across different patient populations.

It is important to note that while these indices can provide valuable information about a patient's condition, they should not be used as the sole basis for clinical decision-making. Rather, they should be considered in conjunction with other factors, such as the patient's overall clinical presentation, treatment preferences, and goals of care.

Tic disorders are a group of conditions characterized by the presence of repetitive, involuntary movements or sounds, known as tics. These movements or sounds can vary in complexity and severity, and they may be worsened by stress or strong emotions.

There are several different types of tic disorders, including:

1. Tourette's disorder: This is a neurological condition characterized by the presence of both motor (movement-related) and vocal tics that have been present for at least one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
2. Persistent (chronic) motor or vocal tic disorder: This type of tic disorder is characterized by the presence of either motor or vocal tics (but not both), which have been present for at least one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
3. Provisional tic disorder: This type of tic disorder is characterized by the presence of motor or vocal tics (or both) that have been present for less than one year. The tics may wax and wane in severity over time, but they do not disappear for more than three consecutive months.
4. Tic disorder not otherwise specified: This category is used to describe tic disorders that do not meet the criteria for any of the other types of tic disorders.

Tic disorders are thought to be caused by a combination of genetic and environmental factors, and they often co-occur with other conditions such as attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). Treatment for tic disorders may include behavioral therapy, medication, or a combination of both.

Psychiatric Status Rating Scales are standardized assessment tools used by mental health professionals to evaluate and rate the severity of a person's psychiatric symptoms and functioning. These scales provide a systematic and structured approach to measuring various aspects of an individual's mental health, such as mood, anxiety, psychosis, behavior, and cognitive abilities.

The purpose of using Psychiatric Status Rating Scales is to:

1. Assess the severity and improvement of psychiatric symptoms over time.
2. Aid in diagnostic decision-making and treatment planning.
3. Monitor treatment response and adjust interventions accordingly.
4. Facilitate communication among mental health professionals about a patient's status.
5. Provide an objective basis for research and epidemiological studies.

Examples of Psychiatric Status Rating Scales include:

1. Clinical Global Impression (CGI): A brief, subjective rating scale that measures overall illness severity, treatment response, and improvement.
2. Positive and Negative Syndrome Scale (PANSS): A comprehensive scale used to assess the symptoms of psychosis, including positive, negative, and general psychopathology domains.
3. Hamilton Rating Scale for Depression (HRSD) or Montgomery-Åsberg Depression Rating Scale (MADRS): Scales used to evaluate the severity of depressive symptoms.
4. Young Mania Rating Scale (YMRS): A scale used to assess the severity of manic or hypomanic symptoms.
5. Brief Psychiatric Rating Scale (BPRS) or Symptom Checklist-90 Revised (SCL-90-R): Scales that measure a broad range of psychiatric symptoms and psychopathology.
6. Global Assessment of Functioning (GAF): A scale used to rate an individual's overall psychological, social, and occupational functioning on a hypothetical continuum of mental health-illness.

It is important to note that Psychiatric Status Rating Scales should be administered by trained mental health professionals to ensure accurate and reliable results.

Comorbidity is the presence of one or more additional health conditions or diseases alongside a primary illness or condition. These co-occurring health issues can have an impact on the treatment plan, prognosis, and overall healthcare management of an individual. Comorbidities often interact with each other and the primary condition, leading to more complex clinical situations and increased healthcare needs. It is essential for healthcare professionals to consider and address comorbidities to provide comprehensive care and improve patient outcomes.

An amputee is a person who has had a limb or extremity removed by trauma, medical illness, or surgical intervention. Amputation may affect any part of the body, including fingers, toes, hands, feet, arms, and legs. The level of amputation can vary from partial loss to complete removal of the affected limb.

There are several reasons why a person might become an amputee:
- Trauma: Accidents, injuries, or violence can result in amputations due to severe tissue damage or irreparable vascular injury.
- Medical illness: Certain medical conditions such as diabetes, peripheral arterial disease, and cancer may require amputation if the affected limb cannot be saved through other treatments.
- Infection: Severe infections that do not respond to antibiotics or other treatments may necessitate amputation to prevent the spread of infection.
- Congenital defects: Some individuals are born with missing or malformed limbs, making them congenital amputees.

Amputees face various challenges, including physical limitations, emotional distress, and social adjustment. However, advancements in prosthetics and rehabilitation have significantly improved the quality of life for many amputees, enabling them to lead active and fulfilling lives.

Brain diseases, also known as neurological disorders, refer to a wide range of conditions that affect the brain and nervous system. These diseases can be caused by various factors such as genetics, infections, injuries, degeneration, or structural abnormalities. They can affect different parts of the brain, leading to a variety of symptoms and complications.

Some examples of brain diseases include:

1. Alzheimer's disease - a progressive degenerative disorder that affects memory and cognitive function.
2. Parkinson's disease - a movement disorder characterized by tremors, stiffness, and difficulty with coordination and balance.
3. Multiple sclerosis - a chronic autoimmune disease that affects the nervous system and can cause a range of symptoms such as vision loss, muscle weakness, and cognitive impairment.
4. Epilepsy - a neurological disorder characterized by recurrent seizures.
5. Brain tumors - abnormal growths in the brain that can be benign or malignant.
6. Stroke - a sudden interruption of blood flow to the brain, which can cause paralysis, speech difficulties, and other neurological symptoms.
7. Meningitis - an infection of the membranes surrounding the brain and spinal cord.
8. Encephalitis - an inflammation of the brain that can be caused by viruses, bacteria, or autoimmune disorders.
9. Huntington's disease - a genetic disorder that affects muscle coordination, cognitive function, and mental health.
10. Migraine - a neurological condition characterized by severe headaches, often accompanied by nausea, vomiting, and sensitivity to light and sound.

Brain diseases can range from mild to severe and may be treatable or incurable. They can affect people of all ages and backgrounds, and early diagnosis and treatment are essential for improving outcomes and quality of life.

The knee joint, also known as the tibiofemoral joint, is the largest and one of the most complex joints in the human body. It is a synovial joint that connects the thighbone (femur) to the shinbone (tibia). The patella (kneecap), which is a sesamoid bone, is located in front of the knee joint and helps in the extension of the leg.

The knee joint is made up of three articulations: the femorotibial joint between the femur and tibia, the femoropatellar joint between the femur and patella, and the tibiofibular joint between the tibia and fibula. These articulations are surrounded by a fibrous capsule that encloses the synovial membrane, which secretes synovial fluid to lubricate the joint.

The knee joint is stabilized by several ligaments, including the medial and lateral collateral ligaments, which provide stability to the sides of the joint, and the anterior and posterior cruciate ligaments, which prevent excessive forward and backward movement of the tibia relative to the femur. The menisci, which are C-shaped fibrocartilaginous structures located between the femoral condyles and tibial plateaus, also help to stabilize the joint by absorbing shock and distributing weight evenly across the articular surfaces.

The knee joint allows for flexion, extension, and a small amount of rotation, making it essential for activities such as walking, running, jumping, and sitting.

A stroke, also known as cerebrovascular accident (CVA), is a serious medical condition that occurs when the blood supply to part of the brain is interrupted or reduced, leading to deprivation of oxygen and nutrients to brain cells. This can result in the death of brain tissue and cause permanent damage or temporary impairment to cognitive functions, speech, memory, movement, and other body functions controlled by the affected area of the brain.

Strokes can be caused by either a blockage in an artery that supplies blood to the brain (ischemic stroke) or the rupture of a blood vessel in the brain (hemorrhagic stroke). A transient ischemic attack (TIA), also known as a "mini-stroke," is a temporary disruption of blood flow to the brain that lasts only a few minutes and does not cause permanent damage.

Symptoms of a stroke may include sudden weakness or numbness in the face, arm, or leg; difficulty speaking or understanding speech; vision problems; loss of balance or coordination; severe headache with no known cause; and confusion or disorientation. Immediate medical attention is crucial for stroke patients to receive appropriate treatment and prevent long-term complications.

Jankovic, Joseph (2015). "Gait disorders". In Jankovic, Joseph (ed.). Movement Disorders, An Issue of Neurologic Clinics. ... Research is being done on whether deep brain stimulation of the pedunculopontine nucleus might be used to improve the gait and ... 2014). "Imagined gait modulates neuronal network dynamics in the human pedunculopontine nucleus" (PDF). Nature Neuroscience. 17 ...
Thomann, K. H.; Dul, M. W. (1996). "Abnormal gait in neurologic disease". Optometry Clinics. 5 (3-4): 181-192. ISSN 1050-6918. ... Takukasaki, K (2013). "Neurophysiology of gait: from the spinal cord to the frontal lobe". Movement Disorders. 28 (11): 1483- ... Astasia abasia Contrapposto Gait abnormality Gait Abnormality Rating Scale Gait analysis Human positions Marche a petit pas ... Circumduction gait: occurs in hemiplegia Waddling gait: occurs in bilateral congenital hip dislocation High stepping gait: ...
... a disorder in which eyes drift involuntarily affecting vision; and gait and balance issues. SCA1 is also commonly present with ... As the disease progresses, more severe neurologic symptoms can appear like dysmetria, where limb movements consistently ... exhibit cognitive disorders. These estimates are consistently higher than the portion with mental health disorders in the ... Many ataxic disorders which were historically identified as Marie's ataxia, olivopontocerebellar atrophy or other names were ...
However this is not specific to EPM and is common to many other neurological disorders. Clinical signs among horses with EPM ... The term EPM refers to the clinical neurologic symptoms caused by the parasite, not infection itself. Most horses infected with ... Apparent lameness, particularly atypical lameness or slight gait asymmetry of the rear limbs are commonly caused by EPM. Focal ... Secondary signs also occur with neurologic disease. Airway abnormalities, such as laryngeal hemiplegia, snoring, or airway ...
Physiotherapy is particularly helpful for patients with motor symptoms (weakness, gait disorders, movement disorders) and ... Aybek S, Vuilleumier P (2016). "Imaging studies of functional neurologic disorders". Functional Neurologic Disorders. Handbook ... "Functional neurologic disorders/conversion disorder". Mayo Clinic. Wessely S, White PD (August 2004). "There is only one ... Functional neurologic disorder or functional neurological disorder (FND) is a condition in which patients experience ...
... gait disorders, neurologic MeSH C23.888.592.413.400 - gait apraxia MeSH C23.888.592.413.450 - gait ataxia MeSH C23.888.592.544 ... sensation disorders MeSH C23.888.592.763.237 - dizziness MeSH C23.888.592.763.393 - hearing disorders MeSH C23.888.592.763. ... communication disorders MeSH C23.888.592.604.150.500 - language disorders MeSH C23.888.592.604.150.500.050 - agraphia MeSH ... language development disorders MeSH C23.888.592.604.150.500.800 - speech disorders MeSH C23.888.592.604.150.500.800.100 - ...
Neurologic Causes of Weakness and Paralysis Chapter 22: Numbness, Tingling, and Sensory Loss Chapter 23: Gait Disorders, ... Neurologic Disorders Section 1: Diagnosis of Neurologic Disorders Chapter 415: Approach to the Patient with Neurologic Disease ... Sleep Disorders Section 4: Disorders of Eyes, Ears, Nose, and Throat Chapter 28: Disorders of the Eye Chapter 29: Disorders of ... Video Library of Gait Disorders Chapter V2: Primary Progressive Aphasia, Memory Loss, and Other Focal Cerebral Disorders ...
In a study investigating high-level gait and balance disorders in elderly adults who had no evidence of rheumatologic, ... orthopedic, or neurologic disease, brain imaging data revealed an association between reduced gray matter density of the PPN ... Takakusaki, K (2017). "Functional neuroanatomy for posture and gait control". Journal of Movement Disorders. 10 (1): 1-17. doi: ... In a clinical case series, three adult males with isolated lesions of the MLR presented with gait hesitation and gait ataxia ...
... cardiac disorders, and other neurologic conditions. There are both inpatient and outpatient services available with each staff ... Advanced rehabilitation technology such as the Zero/G gait training tool and Alter/G anti-gravity treadmill has earned MedStar ... This provides body weight support for gait training. Faculty provides care for thousands suffering from mild to traumatic brain ... This program has also been accredited for treating motion disorders, arthritis, chronic pain syndromes, ...
... it produces a gait characterized by rapid, spasmodic hyperflexion of the hind limbs. Shivers: a rare neuromuscular disorder ... In the horse, it is most commonly caused by pain, but can be due to neurologic or mechanical dysfunction. Lameness is a common ... The walk is often the best gait to evaluate foot placement. The trot is generally the best gait to localize the lameness to a ... and high-stepping gait. Damage to individual nerves will affect the muscles they innervate and subsequently alter gait. Radial ...
Gait abnormality 781.3 Lack of coordination Dysdiadochokinesia Ataxia NOS Hypotonia 781.5 Clubbing of fingers 781.8 Neurologic ... other Iron overload disorder 790.7 Bacteremia (not septicemia) 790.8 Viremia, unspecified 790.9 Other nonspecific findings on ... associated with sleep stages or arousal from sleep 780.57 Unspecified sleep apnea 780.58 Sleep related movement disorder, ...
... of fracture in elderly patients because hyponatremia has been shown to cause subtle neurologic impairment that affects gait and ... Hyponatremia is the most common electrolyte disorder encountered in the elderly patient population. Studies have shown that ...
Cognitive disorders, Dementia, Learning disabilities, Mental disorders due to brain damage). ... as well as gait problems and swallowing difficulties. People have patchy deficits in terms of cognitive testing. They tend to ... The neurologic signs localizing to certain areas of the brain that can be observed are hemiparesis, bradykinesia, hyperreflexia ... In addition, infectious disorders, such as syphilis, can cause arterial damage, strokes, and bacterial inflammation of the ...
Autosomal recessive disorders, Lipid metabolism disorders, Rare diseases, Syndromes). ... If treatment is initiated early in disease the neurologic sequelae may be reversed and further deterioration can be prevented. ... Specifically, a prolonged vitamin E deficiency can lead to the development of limiting ataxia and gait disturbances. Some ... This disorder may also result in fat accumulation in the liver (hepatic steatosis). Because the epithelial cells of the bowel ...
Thorough neurologic examination of the lower extremities, including gait, muscle power, tone, sensation, reflexes, and plantar ... Bedwetting becomes a disorder when it persists after the age at which bladder control usually occurs (4-7 years), and is either ... Bedwetting can also be a symptom of a pediatric neuropsychological disorder called PANDAS. Sleep apnea stemming from an upper ... with reported bedwetting issues are 2.7 times more likely to be diagnosed with Attention deficit hyperactivity disorder. ...
... vascular disease or severe neurologic disorders; previous arthrodesis of the ipsilateral hip or knee or severe deformities of ... Conti S, Lalonde KA, Martin R (November 2006). "Kinematic analysis of the agility total ankle during gait". Foot & Ankle ... and the assessment of its functionality in daily life using gait analysis or videofluoroscopy; the latter is a tool for three- ...
Neurologic examination of individuals with this mutation may show dysmetria in the upper extremities, hyperreflexia, distal ... Individuals appear to have difficulty walking, and report a clumsy, spastic gait which worsens over time. Some additional ... HSP is a category of neurological disorder characterized by spasticity and muscle weakness in the lower limbs. The original ...
... especially obsessive-compulsive disorder but also attention-deficit hyperactivity disorder, affective disorders, tic disorders ... Non-neurologic manifestations of acute rheumatic fever may be present, namely carditis (up to 70% of cases, often subclinical, ... giving an irregular gait and the appearance of skipping or dancing. Underlying the abnormal movements is often low tone ( ... Diagnosis is often delayed and attributed to another condition such as tic disorder or conversion disorder. The controversial ...
... autoimmune neurologic disorders such as multiple sclerosis, sleep disorders, brain injury, headache disorders like migraine, ... or gait disorders, are managed predominantly by specialists in geriatric medicine. Clinical neuropsychologists are often called ... Neurologists diagnose and treat myriad neurologic conditions, including stroke, epilepsy, movement disorders such as ... neuromuscular disorders, sleep medicine, pain management, or movement disorders. In the United States and Canada, neurologists ...
It is not known if the neurologic symptoms seen in survivors are a direct result of the virus or, instead, triggered by the ... Neurologically the individual's coordination, gait and frontal release signs should be observed. Management depends on the ... more than 5 years after he himself had incurred the infection Researchers from the National Institute of Neurological Disorders ... Early results described abdominal, chest, neurologic, musculoskeletal, and ocular challenges faced by survivors. PREVAIL IV ...
This form of gait training has been shown to improve long-term walking speed and a shuffling gait following a one-month ... Agonists at higher doses have also been related to a wide variety of impulse-control disorders. Apomorphine, which is a ... Physicians cite barriers with inability to perform a full neurologic exam in addition to technology and reimbursement issues. ... Task-specific gait training may also lead to long-term gait improvement for patients with Parkinson's disease. Previous ...
Neurologic examination should assess cognitive and mental abilities, cranial nerve function, motor function, deep tendon ... Some patients with polymicrogyria go undiagnosed until they produce children with the disorder who have more severe ... reflexes, sensory function, coordination, and gait (if appropriate). Genetic testing Epilepsy Phenome/Genome Project "Bilateral ... Other specific tests targeting individual neurometabolic disorders can be obtained if clinically suggested. The following may ...
Jomova K, Vondrakova D, Lawson M, Valko M (2010). "Metals, oxidative stress and neurodegenerative disorders". Mol Cell Biochem ... Schapira AH (2009). "Etiology and Pathogenesis of Parkinson Disease". Neurologic Clinics. 27 (3): 583-603. doi:10.1016/j.ncl. ... This transmission inhibition ultimately causes the characteristic Parkinsonian gait with symptoms such as hunched and slowed ... Zlokovic BV (2008). "The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders". Neuron. 57 (2): 178-201. doi: ...
Unlikely Alzheimer's disease: The patient presents a dementia syndrome with a sudden onset, focal neurologic signs, or seizures ... American Psychiatric Association (2000). Diagnostic and Statistical Manual of Mental disorders, 4th Edition Text Revision. ... or gait disturbance early in the course of the illness. The NINCDS-ADRDA Alzheimer's Criteria specify eight cognitive domains ... the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders ...
Journal of Neurologic Science. 11 (4 Suppl): 506-9. doi:10.1017/S0317167100034971. PMID 6391645. CIEQ (Online). "Plaque ... The disease causes progressive damage to the nervous system resulting in symptoms ranging from gait disturbance and speech ... chromosomal localization studies that had previously been judged to be almost impossible in rare autosomal recessive disorders ...
... (also known as "pellagra-like dermatosis" and "Hartnup disorder") is an autosomal recessive metabolic disorder ... Neurologic and psychiatric treatment is needed in patients with severe central nervous system involvement. Citrullinemia ... Mental retardation, short stature, headaches, unsteady gait, and collapsing or fainting are common. Psychiatric problems (such ... Amino acid metabolism disorders, Autosomal recessive disorders, Skin conditions resulting from errors in metabolism, Membrane ...
Differences in leg length observed in DCMO can lead to problems with gait, joint pain and scoliosis. An orthopedic consultation ... However, head circumference and neurologic development should be serially examined. Presence of neurological abnormality or ... Macrocephaly-cutis marmorata telangiectatica congenita: a distinct disorder with developmental delay and connective tissue ...
Thus surgical intervention is a reasonable choice in the presence of a neurologic deficit as a result of instability. In fact, ... Although the anterior subluxation of the atlantoaxial joint is the most common manifestation of the disorder, subluxation can ... gait disturbance, paresthesias, and loss of dexterity (e.g. difficulty buttoning clothing). The inflammatory mediators of RA ... Reiter, Mitchell F.; Boden, Scott D. (1998-12-15). "Inflammatory Disorders of the Cervical Spine". Spine. 23 (24): 2755-2766. ...
"Dynamic Posturography in the Diagnosis and Management of Dizziness and Balance Disorders". Neurologic Clinics. Diagnostic ... Blaszcyk, J. W.; Lowe, D. L.; Hansen, P. D. (1994), Ranges of postural stability and their changes in the elderly, Gait and ... The main indications for CDP are dizziness and vertigo, and postural imbalances (balance disorders). Balance disorders ... particularly in the diagnosis of balance disorders and in physical therapy and postural re-education). Due to the complex ...
Congenital disorders of nervous system, Disorders causing seizures, Pediatrics, Ventricular system, Wikipedia medicine articles ... Hakim's triad of gait instability, urinary incontinence, and dementia is a relatively typical manifestation of the distinct ... Various neurologic conditions may result in communicating hydrocephalus, including subarachnoid/intraventricular hemorrhage, ... However, due to lack of writing, it was unknown how the people thought of the disorder at that time and the ways to treat the ...
Movement disorders are uncommon in spontaneous CSF leaks but occasionally can be one of the major components of the clinical ... The final criteria is that in the rare cases of spontaneous intracranial hypotension with no headache present, the neurologic ... Other symptoms of a CSF leak include photophobia, dizziness and vertigo, gait disturbances, tinnitus, facial numbness or ... A cerebrospinal fluid leak can be either cranial or spinal, and these are two different disorders. A spinal CSF leak can be ...
How to Assess Gait, Stance, and Coordination - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD ... see also Movement and Cerebellar Disorders Overview of Movement and Cerebellar Disorders Voluntary movement requires complex ... Footdrop due to motor weakness causes a steppage gait (lifting the leg higher than normal to avoid catching the foot on surface ... Normal gait, stance, and coordination require integrity of the motor, vestibular, cerebellar, and proprioceptive pathways ( ...
... gait refers to how a person walks. An abnormal gait might be caused by an underlying physical condition, disease or injury. ... ClinicalTrials.gov: Gait Ataxia (National Institutes of Health) * ClinicalTrials.gov: Gait Disorders, Neurologic (National ... National Institute of Neurological Disorders and Stroke) * Gait or Walking Problems (National Multiple Sclerosis Society) - PDF ... Movement disorders, such as Parkinsons disease. *Neurologic diseases, including multiple sclerosis and peripheral nerve ...
Jankovic, Joseph (2015). "Gait disorders". In Jankovic, Joseph (ed.). Movement Disorders, An Issue of Neurologic Clinics. ... Research is being done on whether deep brain stimulation of the pedunculopontine nucleus might be used to improve the gait and ... 2014). "Imagined gait modulates neuronal network dynamics in the human pedunculopontine nucleus" (PDF). Nature Neuroscience. 17 ...
Ataxia/gait disorder. 17 (10.4). 3 (6.7). 10 (12.4). 4 (10.8). 0.632. ... Neurologic symptom. No. (%) patients. Peak parasitemia, no. (%) patients. p value. ,1.0%, n = 45. 1.0%-10.0%, n = 81. ,10.0%, n ... Neurologic Complications of Babesiosis, United States, 2011-2021 Sara Locke1, Jane OBryan1, Adeel S. Zubair, Melissa Rethana, ... Neurologic symptoms during hospital admissions for babesiosis in patients admitted to Yale-New Haven Hospital, New Haven, ...
Functional movement disorder. *Functional neurologic disorder. *Gait disturbance. *Gait unsteadiness. *Guillain Barre syndrome ... Her clinical interest include Neurologic Disorders, Motor Neuron Disease, Arthritis, and Geriatrics. ... She is Medical Director of the Neurologic Disease Rehabilitation subsection of the department. ... Functional Movement Disorders, and Rehabilitation for Multiple Sclerosis and ALS. ...
Plantar fasciitis is a musculoskeletal disorder primarily affecting the fascial enthesis. Although poorly understood, the ... Gait Disorders, Neurologic / physiopathology * Humans * Microcirculation * Neuroanatomy ... Plantar fasciitis is a musculoskeletal disorder primarily affecting the fascial enthesis. Although poorly understood, the ...
Gait Disorders, Neurologic / diagnosis * Gait Disorders, Neurologic / etiology * Gait Disorders, Neurologic / rehabilitation* ... to evaluate how the additional information from three-dimensional gait analysis (3DGA) can influence the reliability. Twenty- ...
See also Introduction to the Neurologic Examination. Introduction to the Neurologic Examination The purpose of the neurologic ... Spinal cord Overview of Spinal Cord Disorders Spinal cord disorders can cause permanent severe neurologic disability. For some ... See also Overview of Peripheral Nervous System Disorders... read more ) or nerve roots (radiculopathy Nerve Root Disorders ... and Lumbosacral Plexus Disorders Disorders of the brachial or lumbosacral plexus cause a painful mixed sensorimotor disorder of ...
Movement Disorders: Neurologic Principles and Practice. Vol 49. McGraw-Hill. 1997:61-672. ... and gait disorder. Most patients have gradual decline in school performance and intellectual abilities. Seizures are uncommon. ... including obsessive compulsive disorder (OCD), attention deficit-hyperactivity disorder, depression and anxiety. [6] ... Movement disorders in mitochondrial myopathies. A study of nine cases with two autopsy studies. Mov Disord. 1990. 5(2):109-17. ...
Learn about the veterinary topic of The Neurologic Examination of Animals. Find specific details on this topic and related ... Muscle Disorders Muscle disorders are often characterized by weakness, fatigability, and stiff, stilted gait. A postural tremor ... Evaluating Gait in the Neurologic Examination of Animals A nonslip surface, such as carpet, grass, or pavement, should be used ... Patients with bilateral limb pain may not walk at all or may have a short-strided, stilted gait, which can mimic neurologic ...
Gait Disorders, Neurologic/chemically induced/drug therapy * Hallucinogens/toxicity * Haloperidol/therapeutic use ...
Treatment is scarce for functional neurological disorder (FND), which requires a multidisciplinary approach. A special report ... Patients with FND have neurologic symptoms such as limb weakness, tremors, gait difficulties, seizures, or cognitive problems ... Functional neurological disorder, formerly called conversion disorder, involves the biological embedding of lived experience in ... Prompt Treatment for Functional Neurological Disorder in Children Is Highly Effective Successful treatment programs can be ...
Gait Disorders - Walking Problems Reviewer(s) Jason Raad, MS, and Rachel Tappan PT, Board-Certified Neurologic Clinical ... Dynamic Gait Index for Parkinson Disease Assesses an individuals ability to modify balance while walking in the presence of ... Gait and aerobic capacity. The American Thoracic Society guidelines for the 6MWT recommend use of a 30-meter or 100-foot ...
Functional neurologic disorder, Carpal tunnel syndrome, Gait unsteadiness, Median neuropathy, Cervical spinal stenosis, Medial ... Shoulder disorder, Head and neck cancer, Sarcopenia, Delirium, Neurologic muscle weakness, Muscle weakness, Nerve compression ... Knee disorder, Movement disorder, Shoulder arthritis, Piriformis syndrome, Knee pain, Lymphedema, Thoracic radiculopathy, ... syndrome, Osteoarthritis, Patellar tendinitis, Neuromuscular disorder, Neurocognitive disorder, Lateral collateral ligament ...
Gait, Gait Disorders,Neurologic, Health, Human, Humans, Intervention, Male, Measurement, Medical, Medicine, Method, Middle Aged ... A score chart of 73 gait items was used to rate each gait analysis. A single rater performed the scoring. Latent class analysis ... A score chart of 73 gait items was used to rate each gait analysis. A single rater performed the scoring. Latent class analysis ... A score chart of 73 gait items was used to rate each gait analysis. A single rater performed the scoring. Latent class analysis ...
Program creates individualized interventions to those affected by neurologic injury or disease. ... Speech & Language: Aphasia, Apraxia, Dysarthria, Voice Disorders. *Sensorimotor: Upper Extremity, Lower Extremity, Gait ... Neurologic Music Therapy is the therapeutic application of music to cognitive, sensory and motor dysfunctions due to neurologic ... Spauldings Approach to Neurologic Music Therapy. NMT at Spaulding helps people at all levels of cognitive function. Our ...
Neurologic and behavioral disorders in people have been seen following long-term ingestion and dermal application of inorganic ... sleeping disorders; and unsteadiness of gait and limbs [14] [16]. ... The neurologic syndrome commonly seen as a result of chronic mercury toxicity is characterized by common CNS symptoms, ... Acrodynia is a complex neurologic syndrome characterized by fine postural or action tremor of the face or extremities, lack of ...
Physical Therapy Specialities Decompression - Neck and Low Back Surgeries: Pre & Post Balance: Vertigo & Dizziness Parkinsons Disease Stroke Multipl ...
Learn and reinforce your understanding of Spinal cord disorders: Pathology review. ... Spinal cord disorders: Pathology review Videos, Flashcards, High Yield Notes, & Practice Questions. ... On neurologic examination, her pupils are small and irregularly shaped and do not react to light, but constrict with ... She has a wide-based gait and cannot maintain balance with her eyes closed. ...
Gait Disorders, Neurologic/epidemiology/etiology, Health Surveys, Humans, Male, Middle Aged, Postural Balance/physiology, ... RESULTS: The prevalence of dizziness (28%), spinning vertigo (14%), and unsteady gait (25%) was significantly higher in divers ... Tobacco Use Disorder/epidemiology/psychology, United States/epidemiology ...
Palavras-Chave: ankle arthrodesis, gait, neurologic disorders, posterior tibial tendon dysfunction. Imprenta: The Journal of ... Resumo: Guillain-Barré syndrome is a serious disorder that occurs when the bodys immune system mistakenly attacks the ...
Frontal Gait -- See Gait Disorders, Neurologic Gait abnormalities that are a manifestation of nervous system dysfunction. These ... conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength ...
Gait disorders lead to a loss of personal freedom, falls and injuries and result in a marked reduction in the quality of life.[ ... also an essential part of the assessment of patient progress during rehabilitation and recovery from the effects of neurologic ... Important Terminology of Gait[edit , edit source]. Gait cycle[edit , edit source]. *The gait cycle is the time from when the ... Normal Gait or Ideal Gait?[edit , edit source]. An "ideal" gait needs to be both safe and energy efficient.[4] For example[4]: ...
... abnormal gait, agnosia, aphasia, asterixis, cerebellar edema, cerebellar disorders, convulsions, coma, CNS depression, ... dysarthria, encephalopathy, facial paralysis, hemiplegia, hyporeflexia, hypotaxia, no light reflex, neurologic reaction, spinal ... Blood and lymphatic system disorders: Lymph disorders (6%).. *Cardiovascular disorders: Cardiac failure (6%), cardiac arrest, ... Metabolism and nutrition disorders: Fluid imbalance (6%), acidosis (3%).. *Eye disorders: Changed visual acuity (6%), visual ...
Judy notes that neurological disorders are some of the most common problems that are manifested in abnormal gaits and can be ... Chiropractic, Neurologic & Infectious Causes. Veterinarians schooled in equine chiropractics may also do an evaluation to check ... Gait (or motion) analysis via high-speed video: High-speed video enables the veterinarian to determine different patterns of ... Widening the investigation into non-orthopedic disorders is an important element for elusive diagnoses, but also a little more ...
... of spatiotemporal gait characteristics appears to have potential for use as an outcome measure for dogs with neurologic disease ... Procedures-Gait was analyzed for velocity, stride length, stride time, stance time, and swing time and compared between groups ... Results-By use of multivariate regression, dogs with neurologic signs, compared with clinically normal dogs, had decreased ... Abstract Objective-To determine the spatiotemporal gait characteristics and associated covariates of clinically normal dogs and ...
Additional therapy with bolus glucose treatment (500 mL of 50% dextrose solution, IV, as a single bolus) in neurologic cases ... Incoordination and gait abnormalities occasionally occur, as do aggression and bellowing. These clinical signs occur in a ... Also see Fatty Liver Disease of Cattle Fatty Liver Disease of Cattle Fatty liver disease is a disorder of highly productive ... In some cases, CNS disturbances are evident (nervous ketosis). Neurologic signs include abnormal licking and chewing, and ...
... disabling neurologic disorder causing resting tremor, muscular rigidity, bradykinesia and impairment of gait. It is estimated ... Broader Impact: Dysfunction of cortico-basal ganglia-thalamic loop has been implicated in other disorders of importance on both ... Dysfunction of cortico-basal ganglia-thalamic (CBT) loop has been implicated in disorders of importance to public health ... obsessive-compulsive disorder, addiction, Tourettes syndrome, dystonias and dyskinesias. Defining the micro-circuitry of the ...
Abstract: The invention provides dosage forms and methods utilizing nicotine to treat symptoms of a neurologic disorder. In ... some embodiments, the invention provides compositions for treatment of gait and balance problems associated with Parkinsons ... Abstract: Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit ... Abstract: Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit ...
  • Dr. Moutvic has presented across the United States, most recently presenting on the topics of Shoulder Pain and Weakness, Severe Copper Deficiency, Functional Movement Disorders, and Rehabilitation for Multiple Sclerosis and ALS. (mayoclinic.org)
  • Is BDNF related to spatial-temporal gait parameters in people with multiple sclerosis? (researchgate.net)
  • This type of gait is a symptom of multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or peripheral neuropathy. (askapollo.com)
  • Dr. Sarah Hopkins is an assistant professor of clinical neurology and section head for multiple sclerosis and neuro-inflammatory disorders in the division of neurology at Children's Hospital of Philadelphia. (cdc.gov)
  • Psychometric properties of outcome measures evaluating decline in gait in cerebellar ataxia: A systematic review. (modushealth.com)
  • Objective home-based gait assessment in spinocerebellar ataxia. (modushealth.com)
  • Several missense mutations in the Kv1.1 gene have been associated with episodic ataxia type-1 syndrome (EA-1), which is characterized by continuous myokymia, episodic attacks of ataxic gait and spastic contractions of skeletal muscles. (uaeu.ac.ae)
  • She has a wide-based gait and cannot maintain balance with her eyes closed. (osmosis.org)
  • These patients also showed wide-based gait, increased deep tendon reflex (DTR), and urinary difficulty. (unboundmedicine.com)
  • OBJECTIVE: The aims of this study were: (1) to identify distinctive gait patterns in patients with MS based on a combined evaluation of kinematics, gait features, and muscle activity during walking and (2) to determine the clinical relevance of these gait patterns. (amsterdamumc.org)
  • CONCLUSIONS: Based on a small set of 9 variables measured with 2-dimensional clinical gait analysis, patients with MS could be divided into 3 different gait classes. (amsterdamumc.org)
  • The area of ​​clinical neurology specialist is responsible for patients with acute and chronic neurological disorders assessment. (ineurociencias.org)
  • 2018). For this reason, it is vital to recognize and assess neurological disorders of balance and posture in clinical settings. (physiosensing.net)
  • Dr. Hopkins would also like to disclose that she's the site principal investigator for clinical trial of SA237 in neuromyelitis optica spectrum disorder. (cdc.gov)
  • Gait abnormalities that are a manifestation of nervous system dysfunction. (edu.au)
  • Broader Impact: Dysfunction of cortico-basal ganglia-thalamic loop has been implicated in other disorders of importance on both the individual and societal levels including Parkinson's disease, schizophrenia, Huntington's disease, depression, obsessive-compulsive disorder, addiction, Tourette's syndrome, dystonias and dyskinesias. (neurodegenerationresearch.eu)
  • 2015). Furthermore, traumatic brain injuries, which are acquired acute neurological disorders can also lead to balance dysfunction. (physiosensing.net)
  • In these patients, a progressive neurologic dysfunction may be the dominant feature. (medscape.com)
  • this often includes seizures, dementia, spasticity, gait impairment, and cerebellar and extrapyramidal dysfunction, typically beginning in the third decade of life and progressing until premature death, often in the sixth decade of life if the condition goes untreated. (medscape.com)
  • Skeletal dysplasias, also known as osteochondrodysplasias, are a heterogeneous group of heritable disorders characterized by abnormalities of cartilage and bone growth, resulting in abnormal shape and size of the skeleton and disproportion of the long bones, spine, and head. (medscape.com)
  • What is abnormal gait? (askapollo.com)
  • But when any of these body parts fail to function efficiently, it causes an abnormal gait. (askapollo.com)
  • An abnormal gait is a symptom of an underlying health condition. (askapollo.com)
  • What are the types of abnormal gait? (askapollo.com)
  • During a physical examination, the doctor observes how a patient walks, which may provide clues about the underlying health condition causing abnormal gait. (askapollo.com)
  • Chédiak-Higashi syndrome (CHS) is an autosomal recessive immunodeficiency disorder characterized by abnormal intracellular protein transport. (medscape.com)
  • Static tremor, abnormal Romberg test results, dysdiadochokinesia, and difficulty with heel to toe gait were more prevalent among thermometer workers than comparison workers. (cdc.gov)
  • Remissions and exacerbations are characteristic of seizures, syncope, and some metabolic disorders. (merckvetmanual.com)
  • Patients with FND have neurologic symptoms such as limb weakness, tremors, gait difficulties, seizures, or cognitive problems that are not explained by traditional neurological disorders. (newswise.com)
  • Overview of Movement and Cerebellar Disorders Voluntary movement requires complex interaction of the corticospinal (pyramidal) tracts, basal ganglia, and cerebellum (the center for motor coordination) to ensure smooth, purposeful movement. (msdmanuals.com)
  • Cerebellar Disorders Cerebellar disorders have numerous causes, including congenital malformations, hereditary ataxias, and acquired conditions. (msdmanuals.com)
  • Objective To investigate cortical activity and gait spatial-temporal parameters in PwMS during two different gait tasks (i.e., unobstructed and obstacle avoidanc. (researchgate.net)
  • Early in the course of the disease, the most obvious symptoms are movement-related, including shaking, rigidity, slowness of movement and difficulty with walking and gait. (tasteforlife.com)
  • End-stage of infection and symptoms can include cancer formation, secondary infections, neurologic issues, etc. (firstvet.com)
  • It is given twice daily and is most helpful in cats that have severe oral inflammation (stomatitis) or are showing neurologic symptoms. (firstvet.com)
  • Newswise - March 9, 2023 - Treatment is scarce for functional neurological disorder (FND) , which requires a multidisciplinary approach. (newswise.com)
  • Cerebrotendinous xanthomatosis (CTX) is a rare genetic disorder of cholesterol and bile acid metabolism that results in systemic and neurologic abnormalities. (medscape.com)
  • METHOD: The patients participated in 2-dimensional video gait analysis, with concurrent measurement of surface electromyography and ground reaction forces. (amsterdamumc.org)
  • Interestingly, many patients are not fully aware of changes in balance and posture, which is frequently one of the earliest signs of a neurological disorder (Nonnekes et al. (physiosensing.net)
  • A gait disorder affects a patient's quality of life and puts them at a higher risk of frequent falls and injuries. (askapollo.com)
  • Guillain-Barré syndrome is a serious disorder that occurs when the body's immune system mistakenly attacks the peripheral nervous system. (unicamp.br)
  • Within neurological disorders it is possible to observe serious alterations in matters of peripheral and central nervous system that have a serious impact on postural control , such as somatic-sensorial impairments, including changes in proprioception resulting from slowed transmission of somatic sensory impulses or changes in mechanoreceptors, alterations in the integration of sensory inputs, changes in reflexes, muscle strength, neuromuscular function, and muscle tonus, among others (Nonnekes et al. (physiosensing.net)
  • DESCRIPTION (provided by applicant): Parkinson's disease is a chronic, disabling neurologic disorder causing resting tremor, muscular rigidity, bradykinesia and impairment of gait. (neurodegenerationresearch.eu)
  • This neurologic movement disorder is characterized by resting tremor and stiff movement and is benefitted by medications that raise the neurotransmitter dopamine. (tasteforlife.com)
  • Balance control impairment is often present in patients suffering from these disorders, highly impacting daily life. (physiosensing.net)
  • Research is being done on whether deep brain stimulation of the pedunculopontine nucleus might be used to improve the gait and postural difficulties found in Parkinson's disease. (wikipedia.org)
  • When these body parts fail to function, it causes walking difficulties or gait disorders. (askapollo.com)
  • Unsteady gait was noted in a 2-year-old boy with a lumboperitoneal (LP) shunt that had been inserted 1 year earlier for increased head circumference caused by communicating hydrocephalus. (tmu.edu.tw)
  • The unsteady gait recovered completely and scoliosis improved. (tmu.edu.tw)
  • Myopathic gait can also be a symptom of muscular dystrophy , other muscle diseases, or spinal muscle weakness. (askapollo.com)
  • Outcomes: All assessments of limb movement and balance ability showed improvements after intervention for the limb and gait subsections of the PSP rating scale. (fujita-hu.ac.jp)
  • After intervention, improvements in festinating gait and rapid walking pace were noted on the UPDRS Part 3 (2 to 1 point) and 10-meter walk test (1.65 m/s to 1.10 m/s). (fujita-hu.ac.jp)
  • His goals were to improve limb movement, balance ability, and festinating gait over the 4-week LSVT BIG® program. (fujita-hu.ac.jp)
  • Footdrop due to motor weakness causes a steppage gait (lifting the leg higher than normal to avoid catching the foot on surface irregularities). (msdmanuals.com)
  • A patient with a myopathic gait walks with a side-to-side movement, often due to weakness in the pelvic area. (askapollo.com)
  • She is Medical Director of the Neurologic Disease Rehabilitation subsection of the department. (mayoclinic.org)
  • Rehabilitation for neurologic conditions. (mayoclinic.org)
  • Two hundred years later, Huntington described hereditary chorea and suggested that this movement disorder was similar to that described by Sydenham. (medscape.com)
  • Functional neurological disorder, formerly called conversion disorder, involves the biological embedding of lived experience in the body and brain. (newswise.com)
  • RESULTS: Our results showed that both healthy older and young adults recruited a network of brain regions comprising the bilateral supplementary motor cortex and primary motor cortex, right prefrontal cortex, and cerebellum, during motor imagery of gait. (ox.ac.uk)
  • Based on the initial presentation, both Mario and Donna have some form of spinal cord disorder. (osmosis.org)
  • RESULTS: Analysis of the 73 gait variables revealed that 9 variables could distinguish 3 clinically meaningful gait classes. (amsterdamumc.org)
  • An individual's gait pattern is influenced by age, personality, mood and sociocultural factors. (physio-pedia.com)
  • If the device or brace improves an individual's safety, confidence, and/or unloads the injured structure, then it is a positive addition to the gait pattern. (physio-pedia.com)
  • Although gait classifications are available in cerebral palsy and stroke, relevant knowledge in MS is scarce. (amsterdamumc.org)
  • This kind of gait is a result of a stroke . (askapollo.com)
  • The diplegic gait develops due to cerebral palsy , stroke, and head trauma. (askapollo.com)
  • Column percentages do not sum to 100% due to many patients being affected by multiple neurologic conditions throughout hospitalization. (cdc.gov)
  • For example, whereas congenital or developmental diseases occur most often in young patients, neoplasia and degenerative disorders are more common in older patients. (merckvetmanual.com)
  • Kasia Kozlowska, MD, PhD, a child and adolescent psychiatrist at The Children's Hospital at Westmead in Sydney, Australia, and colleagues explain the scarcity of treatment is global, in part "the result of long-standing stigma and ingrained belief that patients with FND do not suffer from a real ("organic") disorder and that they therefore do not require, or even deserve, treatment. (newswise.com)
  • Neuro : neurologic problems cancer patients. (ineurociencias.org)
  • Patients with balance disorders present a higher fall risk leading to limited activity capacity and restrictions in participation in daily life situations, which result in social isolation and physical inactivity and its underlying consequences (Kwakkel et al. (physiosensing.net)
  • Neurologic Music Therapy is the therapeutic application of music to cognitive, sensory and motor dysfunctions due to neurologic disease or injury. (spauldingrehab.org)
  • In the same line, gait in pwMS requires a higher cognitive resource, mainly during complex walking. (researchgate.net)
  • 2014). "Imagined gait modulates neuronal network dynamics in the human pedunculopontine nucleus" (PDF). (wikipedia.org)
  • This finding provides additional evidence that CTX is a primary neuronal disorder. (medscape.com)
  • Neurologic involvement is variable but often includes peripheral neuropathy. (medscape.com)
  • The efficacy of new treatments such as deep brain stimulation (DBS) to the subthalamic nucleus (STN) or the internal segment of the globus pallidus (GPi) highlights the fact that Parkinson's disease is a network disorder, involving alteration of the dynamics within and between the nuclei of the basal ganglia, the thalamus and the cortex. (neurodegenerationresearch.eu)
  • Defining the micro-circuitry of the cortio-basal ganglia-thalamic loop is not only a critical step towards understanding alternative therapeutic interventions in Parkinson's disease, it has the potential to advance new therapeutic options for individuals with other disorders with basal ganglia involvement. (neurodegenerationresearch.eu)
  • CONCLUSIONS: Besides demonstrating a general overlap in brain regions recruited in young and older participants, this study shows age-related changes in cerebral activation during mental imagery of gait. (ox.ac.uk)
  • A particular form of gait and the most common of human locomotor patterns. (physio-pedia.com)
  • The neurologic examination begins the moment the veterinarian first sees the patient. (merckvetmanual.com)
  • Many parts of the neurologic examination cannot be carried out in a comatose or sedated patient. (merckvetmanual.com)
  • On neurologic examination, her pupils are small and irregularly shaped and do not react to light, but constrict with accommodation. (osmosis.org)
  • Task difficulty was modulated to investigate differential activation for precise control of gait. (ox.ac.uk)
  • For example, causes and treatments of common lameness disorders in aging horses are significantly different from those seen in youngsters. (horseillustrated.com)
  • Many different diseases and conditions can affect your gait and lead to problems with walking. (medlineplus.gov)
  • Diseases that progress over several days include inflammatory and metabolic disorders, as well as some tumors. (merckvetmanual.com)
  • Typified by short stature (defined as height that is three or more standard deviations below the mean height for age), skeletal dysplasias can be accompanied by involvement of other systems, including the neurologic, respiratory, and cardiac systems. (medscape.com)