Gerstmann Syndrome
A disorder of cognition characterized by the tetrad of finger agnosia, dysgraphia, DYSCALCULIA, and right-left disorientation. The syndrome may be developmental or acquired. Acquired Gerstmann syndrome is associated with lesions in the dominant (usually left) PARIETAL LOBE which involve the angular gyrus or subjacent white matter. (From Adams et al., Principles of Neurology, 6th ed, p457)
Aphasia
A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.
Dysarthria
Disorders of speech articulation caused by imperfect coordination of pharynx, larynx, tongue, or face muscles. This may result from CRANIAL NERVE DISEASES; NEUROMUSCULAR DISEASES; CEREBELLAR DISEASES; BASAL GANGLIA DISEASES; BRAIN STEM diseases; or diseases of the corticobulbar tracts (see PYRAMIDAL TRACTS). The cortical language centers are intact in this condition. (From Adams et al., Principles of Neurology, 6th ed, p489)
Speech Disorders
Stuttering
A disturbance in the normal fluency and time patterning of speech that is inappropriate for the individual's age. This disturbance is characterized by frequent repetitions or prolongations of sounds or syllables. Various other types of speech dysfluencies may also be involved including interjections, broken words, audible or silent blocking, circumlocutions, words produced with an excess of physical tension, and monosyllabic whole word repetitions. Stuttering may occur as a developmental condition in childhood or as an acquired disorder which may be associated with BRAIN INFARCTIONS and other BRAIN DISEASES. (From DSM-IV, 1994)
Apraxias
A group of cognitive disorders characterized by the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function. The two major subtypes of this condition are ideomotor (see APRAXIA, IDEOMOTOR) and ideational apraxia, which refers to loss of the ability to mentally formulate the processes involved with performing an action. For example, dressing apraxia may result from an inability to mentally formulate the act of placing clothes on the body. Apraxias are generally associated with lesions of the dominant PARIETAL LOBE and supramarginal gyrus. (From Adams et al., Principles of Neurology, 6th ed, pp56-7)
Progressive multifocal leukoencephalopathy in a patient with acquired immunodeficiency syndrome (AIDS) manifesting Gerstmann's syndrome. (1/9)
We reported a case of acquired immunodeficiency syndrome (AIDS) via multiple blood transfusions, who manifested progressive multifocal leukoencephalopathy (PML) about 18 months after the development of AIDS. PML initiated with right hemiparesis, dysphasia, and Gerstmann's syndrome and resulted in death within 2 months after the onset. Neuroimaging examinations revealed white matter lesions mainly in the left posterior parietal lobe. The cortical gray matter also showed abnormal signal intensity. Peripheral CD4+ lymphocyte count was 81/microl. Routine cerebrospinal fluid (CSF) examinations were negative. CSF antibodies against herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus as well as serum antibody against toxoplasma gondii were negative. Though autopsy or biopsy of the brain was not performed, JC virus genomes were detected in the CSF sample by a polymerase chain reaction, and their sequencing showed unique alterations of the regulatory regions, characteristic to PML-type JC virus. (+info)A pure case of Gerstmann syndrome with a subangular lesion. (2/9)
The four symptoms composing Gerstmann's syndrome were postulated to result from a common cognitive denominator (Grundstorung) by Gerstmann himself. He suggested that it is a disorder of the body schema restricted to the hand and fingers. The existence of a Grundstorung has since been contested. Here we suggest that a common psychoneurological factor does exist, but should be related to transformations of mental images rather than to the body schema. A patient (H.P.) was studied, who presented the four symptoms of Gerstmann's syndrome in the absence of any other neuropsychological disorders. MRI showed a focal ischaemic lesion, situated subcortically in the inferior part of the left angular gyrus and reaching the superior posterior region of T1. The cortical layers were spared and the lesion was seen to extend to the callosal fibres. On the basis of an extensive cognitive investigation, language, praxis, memory and intelligence disorders were excluded. The four remaining symptoms (finger agnosia, agraphia, right-left disorientation and dyscalculia) were investigated thoroughly with the aim of determining any characteristics that they might share. Detailed analyses of the tetrad showed that the impairment was consistently attributable to disorders of a spatial nature. Furthermore, cognitive tests necessitating mental rotation were equally shown to be impaired, confirming the essentially visuospatial origin of the disturbance. In the light of this report, the common cognitive denominator is hypothesized to be an impairment in mental manipulation of images and not in body schema. (+info)Evaluation and outcome of aphasia in patients with severe closed head trauma. (3/9)
In this study long-term observation of 12 patients with aphasia secondary to severe closed head trauma took place. The most frequent symptoms were amnestic aphasia and verbal paraphasia. Only one patient with a constant slow wave EEG focus in the dominant hemisphere had severe receptive symptoms. In all other patients the aphasia recovered rather well, though not totally, but the presence and degree of concomitant neuropsychological disorders were most important for the final outcome. (+info)The Gerstmann syndrome in Alzheimer's disease. (4/9)
BACKGROUND: It remains unclear from lesion studies whether the four signs of the Gerstmann syndrome (finger agnosia, acalculia, agraphia, and right-left confusion) cluster because the neuronal nets that mediate these activities have anatomical proximity, or because these four functions share a common network. If there is a common network, with degeneration, as may occur in Alzheimer's disease, each of the signs associated with Gerstmann's syndrome should correlate with the other three signs more closely than they correlate with other cognitive deficits. METHODS: Thirty eight patients with probable Alzheimer's disease were included in a retrospective analysis of neuropsychological functions. RESULTS: The four Gerstmann's syndrome signs did not cluster together. Finger naming and calculations were not significantly correlated. Right-left knowledge and calculations also did not correlate. CONCLUSIONS: The four cognitive functions impaired in Gerstmann's syndrome do not share a common neuronal network, and their co-occurrence with dominant parietal lobe injuries may be related to the anatomical proximity of the different networks mediating these functions. (+info)Angular gyrus syndrome mimicking depressive pseudodementia. (5/9)
A 67-year-old left-handed woman with a diagnosis of pseudodementia was being treated for depression with little benefit. Neuropsychological evaluations revealed features of angular gyrus syndrome, namely, agraphia, alexia, Gerstmann's syndrome and behavioural manifestations such as depression, poor memory, frustration and irritability. A computed tomographic scan showed a right occipito-temporal infarction, which had occurred 18 months earlier. The patient demonstrated aspects of language dysfunction associated with the syndrome and showed reversed lateralization of cerebral functions. Recognizing and distinguishing between angular gyrus syndrome and depression is important because the appropriate therapies differ. The use of the term pseudodementia can be misleading. (+info)Gerstmann's syndrome: can cardiac myxoma be the cause? (6/9)
Cardiac myxomas are primary cardiac tumours. Clinical presentations vary. Central nervous embolism has been a constant association. We describe a case of a 40-year-old female who presented with neurological signs and symptoms of Gerstmann's syndrome secondary to a left atrial myxoma. (+info)The enigma of Gerstmann's syndrome revisited: a telling tale of the vicissitudes of neuropsychology. (7/9)
(+info)Gerstmann's syndrome. (8/9)
Although Gerstmann's syndrome has been well documented since it was characterised in the latter half of last century, there has not been much literature on it in the last few years. We present a classical case in a patient who was admitted into hospital for an unrelated problem. We conclude that clinical examination still has a valuable role in neurology, despite the availability of excellent imaging techniques. (+info)Gerstmann syndrome is a rare neurological disorder characterized by the tetrad of symptoms including finger agnosia, agraphia, acalculia, and right-left disorientation, typically associated with lesions in the dominant parietal lobe.
Gerstmann syndrome is a rare neurological disorder primarily characterized by the following four symptoms:
1. Finger agnosia - inability to identify or recognize fingers on their own hand, often struggling to distinguish between similar fingers like index and middle finger.
2. Left-right disorientation - difficulty determining left from right, sometimes affecting body awareness and spatial orientation.
3. Agraphia - an impairment in writing abilities, including difficulties with spelling, grammar, or composing coherent texts.
4. Acalculia - inability to perform basic arithmetic calculations or have trouble understanding numerical concepts.
These symptoms are typically associated with damage to the dominant parietal lobe, specifically within the angular gyrus region of the brain. Gerstmann syndrome is often observed in individuals who have experienced stroke, brain injury, or other forms of neurological damage. It's important to note that not all individuals with Gerstmann syndrome will exhibit all four symptoms, and some may experience additional cognitive or motor impairments depending on the extent of the brain damage.
Aphasia is a disorder resulting from damage to the language areas of the brain, causing impairment or loss of ability to understand or produce spoken or written language.
Aphasia is a medical condition that affects a person's ability to communicate. It is caused by damage to the language areas of the brain, most commonly as a result of a stroke or head injury. Aphasia can affect both spoken and written language, making it difficult for individuals to express their thoughts, understand speech, read, or write.
There are several types of aphasia, including:
1. Expressive aphasia (also called Broca's aphasia): This type of aphasia affects a person's ability to speak and write clearly. Individuals with expressive aphasia know what they want to say but have difficulty forming the words or sentences to communicate their thoughts.
2. Receptive aphasia (also called Wernicke's aphasia): This type of aphasia affects a person's ability to understand spoken or written language. Individuals with receptive aphasia may struggle to follow conversations, comprehend written texts, or make sense of the words they hear or read.
3. Global aphasia: This is the most severe form of aphasia and results from extensive damage to the language areas of the brain. People with global aphasia have significant impairments in both their ability to express themselves and understand language.
4. Anomic aphasia: This type of aphasia affects a person's ability to recall the names of objects, people, or places. Individuals with anomic aphasia can speak in complete sentences but often struggle to find the right words to convey their thoughts.
Treatment for aphasia typically involves speech and language therapy, which aims to help individuals regain as much communication ability as possible. The success of treatment depends on various factors, such as the severity and location of the brain injury, the individual's motivation and effort, and the availability of support from family members and caregivers.
Dysarthria is a motor speech disorder resulting from neurological injury or disease, characterized by disturbances in the muscle control and coordination required for clear and precise articulation, respiration, phonation, and prosody during speech production.
Dysarthria is a motor speech disorder that results from damage to the nervous system, particularly the brainstem or cerebellum. It affects the muscles used for speaking, causing slurred, slow, or difficult speech. The specific symptoms can vary depending on the underlying cause and the extent of nerve damage. Treatment typically involves speech therapy to improve communication abilities.
Speech disorders are communication impairments characterized by difficulty in articulation, voice production, or resonance, which may affect a person's ability to speak clearly and be understood by others.
Speech disorders refer to a group of conditions in which a person has difficulty producing or articulating sounds, words, or sentences in a way that is understandable to others. These disorders can be caused by various factors such as developmental delays, neurological conditions, hearing loss, structural abnormalities, or emotional issues.
Speech disorders may include difficulties with:
* Articulation: the ability to produce sounds correctly and clearly.
* Phonology: the sound system of language, including the rules that govern how sounds are combined and used in words.
* Fluency: the smoothness and flow of speech, including issues such as stuttering or cluttering.
* Voice: the quality, pitch, and volume of the spoken voice.
* Resonance: the way sound is produced and carried through the vocal tract, which can affect the clarity and quality of speech.
Speech disorders can impact a person's ability to communicate effectively, leading to difficulties in social situations, academic performance, and even employment opportunities. Speech-language pathologists are trained to evaluate and treat speech disorders using various evidence-based techniques and interventions.
"Stuttering is a speech disorder characterized by the repetition, prolongation, or cessation of sounds, syllables, or words, which disrupts the normal flow of speech."
Stuttering is a speech disorder characterized by the repetition or prolongation of sounds, syllables, or words, as well as involuntary silent pauses or blocks during fluent speech. These disruptions in the normal flow of speech can lead to varying degrees of difficulty in communicating effectively and efficiently. It's important to note that stuttering is not a result of emotional or psychological issues but rather a neurological disorder involving speech motor control systems. The exact cause of stuttering remains unclear, although research suggests it may involve genetic, neurophysiological, and environmental factors. Treatment typically includes various forms of speech therapy to improve fluency and communication strategies to manage the challenges associated with stuttering.
Apraxias are motor speech disorders resulting from neurological damage, characterized by the inability to perform learned movements and gestures despite having intact muscle function and understanding of what needs to be done.
Apraxia is a motor disorder characterized by the inability to perform learned, purposeful movements despite having the physical ability and mental understanding to do so. It is not caused by weakness, paralysis, or sensory loss, and it is not due to poor comprehension or motivation.
There are several types of apraxias, including:
1. Limb-Kinematic Apraxia: This type affects the ability to make precise movements with the limbs, such as using tools or performing complex gestures.
2. Ideomotor Apraxia: In this form, individuals have difficulty executing learned motor actions in response to verbal commands or visual cues, but they can still perform the same action when given the actual object to use.
3. Ideational Apraxia: This type affects the ability to sequence and coordinate multiple steps of a complex action, such as dressing oneself or making coffee.
4. Oral Apraxia: Also known as verbal apraxia, this form affects the ability to plan and execute speech movements, leading to difficulties with articulation and speech production.
5. Constructional Apraxia: This type impairs the ability to draw, copy, or construct geometric forms and shapes, often due to visuospatial processing issues.
Apraxias can result from various neurological conditions, such as stroke, brain injury, dementia, or neurodegenerative diseases like Parkinson's disease and Alzheimer's disease. Treatment typically involves rehabilitation and therapy focused on retraining the affected movements and compensating for any residual deficits.
'Speech' in the medical context refers to the ability to produce and articulate words and sentences with correct grammar and syntax, using the vocal organs, for communication and self-expression.
Speech is the vocalized form of communication using sounds and words to express thoughts, ideas, and feelings. It involves the articulation of sounds through the movement of muscles in the mouth, tongue, and throat, which are controlled by nerves. Speech also requires respiratory support, phonation (vocal cord vibration), and prosody (rhythm, stress, and intonation).
Speech is a complex process that develops over time in children, typically beginning with cooing and babbling sounds in infancy and progressing to the use of words and sentences by around 18-24 months. Speech disorders can affect any aspect of this process, including articulation, fluency, voice, and language.
In a medical context, speech is often evaluated and treated by speech-language pathologists who specialize in diagnosing and managing communication disorders.
Speech production measurement is the quantitative analysis and assessment of various spatiotemporal, acoustic, and articulatory aspects involved in the planning, execution, and control of spoken language to diagnose and monitor speech disorders or improve communication effectiveness.
Speech production measurement is the quantitative analysis and assessment of various parameters and characteristics of spoken language, such as speech rate, intensity, duration, pitch, and articulation. These measurements can be used to diagnose and monitor speech disorders, evaluate the effectiveness of treatment, and conduct research in fields such as linguistics, psychology, and communication disorders. Speech production measurement tools may include specialized software, hardware, and techniques for recording, analyzing, and visualizing speech data.
Gerstmann syndrome
It is named after Jewish Austrian-born American neurologist Josef Gerstmann. Gerstmann syndrome is characterized by four ... There are few reports of the syndrome, sometimes called developmental Gerstmann syndrome, in children. The cause is not known. ... "What ever happened to developmental Gerstmann's syndrome? Links to other pediatric, genetic, and neurodevelopmental syndromes ... Gerstmann syndrome is typically associated with damage to the inferior parietal lobule of the dominant hemisphere. It is ...
Gerstmann-Sträussler-Scheinker syndrome
... , MedicineNet.com ITALIAN ASSOCIATION AGAINST GERSTMANN STRAUSSLER SCHEINKER'S DISEASE ( ... Gerstmann-Sträussler-Scheinker syndrome (GSS) is an extremely rare, always fatal (due to it being caused by prions) ... Collins S, McLean CA, Masters CL (September 2001). "Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: ... March 1989). "Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome". Nature. 338 (6213): 342-5. Bibcode ...
Josef Gerstmann
Gerstmann died on March 23, 1969, in his New York apartment. Gerstmann syndrome and Gerstmann-Sträussler-Scheinker syndrome are ... "Some posthumous notes on the Gerstmann syndrome" by J. Gerstmann. Wiener Zeitschr Nervenheilk 28:12-19 (1970) "Gerstmann's+ ... 1940 "Some notes on the Gerstmann syndrome". Neurology 7: 866-869 (1957) PSYCHOLOGICAL AND PHENOMENOLOGICAL ASPECTS OF ... Initially Gerstmann worked at the Springfield / Ohio State Hospital, and from 1940 to 1941 as a research assistant and as a ...
Ordinal numerical competence
Benton, A.L. (1992). "Gerstmann's Syndrome". Arch. Neurol. 49 (5): 445-447. doi:10.1001/archneur.1992.00530290027007. PMID ...
Nonverbal learning disorder
Forrest, Bonny J. (2011). "Developmental Gerstmann Syndrome". In Kreutzer, Jeffrey S.; DeLuca, John; Caplan, Bruce (eds.). ... hemisphere brain damage and developmental right hemisphere syndrome social-emotional processing disorder Gerstmann syndrome ... Early researchers in the syndrome of NVLD Johnson and Myklebust characterize how the children appear in a classroom: "An ... In some cases, especially the form of autism previously called Asperger syndrome, the overlap can be significant; a major ...
Angular gyrus
Gerstmann, J (1940). "Syndrome of finger agnosia, disorientation for right and left, agraphia and acalculia-Local diagnostic ... Damage to the angular gyrus manifests as Gerstmann syndrome. Damage may impair one or more of the below functions. Dysgraphia/ ... Carota A, Di Pietro M, Ptak R, Poglia D, Schnider A (2004). "Defective spatial imagery with pure Gerstmann's syndrome". Eur. ... Vallar G (July 2007). "Spatial neglect, Balint-Homes' and Gerstmann's syndrome, and other spatial disorders". CNS Spectr. 12 (7 ...
MacDonald Critchley
London, Edward Arnold, 1953 The Enigma of Gerstmann's Syndrome. Oxford, Brain, 1966 Music and the Brain: Studies in the ... Adie-Critchley syndrome: A syndrome of forced grasping and groping. Klein-Levine- Critchley syndrome: A syndrome of ... Levine-Critchley syndrome: Acanthocytosis Neuroacanthocytosis with neurologic disorders detailed by Edmund Critchley not ...
Acalculia
In 1940, Gerstmann claimed that acalculia is associated with aspects of Gerstmann syndrome, which include right-left confusion ... Instead, it may be labeled as one of its symptoms, and lead to the eventual diagnosis of Gerstmann syndrome. "Provided that ... Gerstmann syndrome and similar symptom combinations are outcomes, not diseases. Treatment, therefore, is dedicated to the ... "Gerstmann syndrome and similar posterior parietal symptom combinations (like acalculia) are usually the result of focal ...
Ernst Sträussler
Today this condition is known as Gerstmann-Sträussler-Scheinker syndrome (GSS). Anlage- und Bildungsfehler des ... Gerstmann, Josef; Sträussler, Ernst; Scheinker, I. (December 1935). "Über eine eigenartige hereditär- familiäre Erkrankung des ... In 1936 with neurologists Josef Gerstmann (1887-1969) and Ilya Scheinker (1902-1954), he described a rare prion disease that is ...
Ataxia
Vallar G (July 2007). "Spatial neglect, Balint-Homes' and Gerstmann's syndrome, and other spatial disorders". CNS Spectrums. 12 ... Optic ataxia is usually part of Balint's syndrome, but can be seen in isolation with injuries to the superior parietal lobule, ... An example of X-linked ataxic condition is the rare fragile X-associated tremor/ataxia syndrome or FXTAS. Arnold-Chiari ... Maenhoudt W, Ramboer K, Maqueda V (February 2016). "A Rare Cause of Dizziness and Gait Ataxia: CLIPPERS Syndrome". Journal of ...
Amorphosynthesis
Gerstmann syndrome: A patient is unable to recognize his/her finger. A patient is unable to differentiate right from left. A ... while patients with left parietal lobe lesions presented symptoms such as Gerstmann syndrome, parietal apraxia and construction ...
Karen Ashe
"Linkage of a prion protein missense variant to Gerstmann‑Sträussler syndrome", describing the discovery of a mutation linked to ... "Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome". Nature. 338 (6213): 342-345. Bibcode:1989Natur. ... "Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome". Nature. 338 (6213): 342-345. Bibcode:1989Natur. ...
Episode 1067
After investigating, Dylan diagnoses Gloria with Gerstmann syndrome and a minor stroke; upset, Gloria lashes out at Dylan, who ...
National Prion Clinic (UK)
Diagnosis of Gerstmann-Straussler syndrome in familial dementia with prion protein gene analysis. Lancet 1989; 2: 15-7 "Report ... Prion diseases comprise Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and ...
Agraphia
Gerstmann's syndrome is caused by a lesion of the dominant (usually the left) parietal lobe, usually an angular gyrus lesion. ... Gerstmann syndrome agraphia is the impairment of written language production associated with the following structural symptoms ... Rusconi E, Pinel P, Dehaene S, Kleinschmidt A (February 2010). "The enigma of Gerstmann's syndrome revisited: a telling tale of ... All four of these symptoms result from pathway lesions.[citation needed] Gerstmann's syndrome may additionally be present with ...
Glossary of psychiatry
Left-right disorientation is one of the four cardinal signs of Gerstmann's syndrome. Scanning speech is an ataxic dysarthria in ... Brain fag syndrome is an example of a culture-bound syndrome. "Brain fag" was once a common term for mental exhaustion. Today, ... Anton syndrome, occasionally known as Anton-Babinski syndrome, is a form of cortical blindness in which the individual denies ... Capgras syndrome and several other related disorders are referred to as "delusional misidentification syndrome". Catalepsy is ...
Autotopagnosia
Damage to the left parietal lobe can result in what is called Gerstmann syndrome. It can include right-left confusion, a ... This particular ailment, known as Gerstmann syndrome, is often seen in patients with a lesion on their left angular gyrus, ... Gerstmann studied patients whose deficits were in the body schema and thus lacked the ability to recognize, identify or name ... Josef Gerstmann (1887-1969) first developed the term somatotopagnosia, meaning the lack of knowledge about the body space. ...
Finger agnosia
... as well as the other symptoms of Gerstmann Syndrome, also known as Angular Gyrus Syndrome. In a study by Rusconi et al., ... It is one of a tetrad of symptoms in Gerstmann syndrome, although it is also possible for finger agnosia to exist on its own ... Gerstmann, J. Syndrome of Finger Agnosia, disorientation for right and left, Agraphia, and Acalculia. Archives of Neurology and ... Gerstmann, J. Syndrome of Finger Agnosia, disorientation for right and left, Agraphia, and Acalculia. Archives of Neurology and ...
Variably protease-sensitive prionopathy
Some have suggested the disease may be a sporadic form of Gerstmann-Sträussler-Scheinker syndrome (GSS). In 2013, Zou W.Q. and ...
Posterior cortical atrophy
PCA may also be correlated with Lewy body disease, Creutzfeldt-Jakob disease, Bálint's syndrome, and Gerstmann syndrome. In ... Posterior cortical atrophy (PCA), also called Benson's syndrome, is a rare form of dementia which is considered a visual ... Bernard; Alexis Brice (September 2004). "Benson's syndrome or Posterior Cortical Atrophy" (PDF). Orphanet Encyclopedia. ...
Neuroanatomy of memory
Damage to the left side of the parietal lobe can result in what is called Gerstmann syndrome. It includes right-left confusion ... Such symptoms are often present in those who suffer from dystonia, athymhormic syndrome, Fahr's syndrome, Huntington's disease ... Neglect syndrome tends to be more prevalent on the right side of the parietal lobe, because the right mediates attention to ... Damage to the parietal lobe results in the syndrome 'neglect' which is when patients treat part of their body or objects in ...
Dyscalculia
This has been observed in individuals with Gerstmann syndrome, of which dyscalculia is one of constellation of symptoms. ... It is sometimes colloquially referred to as "math dyslexia", though this analogy is misleading as they are distinct syndromes. ... Dyscalculia has also been associated with Turner syndrome and people who have spina bifida. Mathematical disabilities can occur ...
Brain
ISBN 978-1-58243-162-8. Collins, S; McLean CA; Masters CL (2001). "Gerstmann-Straussler-Scheinker syndrome, fatal familial ...
Jazz Raycole
... a pregnant woman who has Gerstmann-Straussler-Scheinker syndrome, in short-lived series Council of Dads. In 2020, Raycole was ...
Major prion protein
Collins S, McLean CA, Masters CL (2001). "Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, and kuru: a review ... Gerstmann-Sträussler-Scheinker syndrome (GSS), kuru, and variant Creutzfeldt-Jakob disease (vCJD). Similarities exist between ... glutamic acid-200 is replaced by lysine while valine is present at amino acid 129 Gerstmann-Sträussler-Scheinker syndrome - ... suggesting a new phenotype for Gerstmann-Sträussler-Scheinker syndrome. The same study proposed sequencing PRNP in cases of ...
Brain as food
Collins, S; McLean CA; Masters CL (2001). "Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, and kuru: a review ...
Transmissible spongiform encephalopathy
Collins S, McLean CA, Masters CL (2001). "Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, and kuru: a review ... Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia, and kuru, as well as the recently discovered variably ... The first case was identified as a fatal wasting syndrome in the 1960s. It was then recognized as a transmissible spongiform ...
Constructional apraxia
... tried to isolate the cause to left hemisphere lesions in the parietal lobe because of its similarities to Gerstmann syndrome; ... "Understanding the parietal lobe syndrome from a neurophysiological and evolutionary perspective". Eur. J. Neurosci. 31 (12): ...
Ilya Scheinker
... who in 1936 collaborated with Josef Gerstmann and Ernst Sträussler to describe Gerstmann-Sträussler-Scheinker syndrome, a ... Gerstmann, Josef; Sträussler, Ernst; Scheinker, I. (December 1935). "Über eine eigenartige hereditär- familiäre Erkrankung des ... Zeidman, Lawrence A.; Ziller, Matthias Georg; Shevell, Michael (2014-07-15). "Gerstmann, Sträussler, and Scheinker: The ... persecution of the men behind the syndrome". Neurology. 83 (3): 272-277. doi:10.1212/WNL.0000000000000606. ISSN 0028-3878. PMID ...
Gerstmann
American neuropsychologist Gerstmann syndrome, a neuropsychological disorder Gerstmann-Sträussler-Scheinker syndrome, a very ... Gerstmann is a surname. Notable people with the surname include: Jeff Gerstmann (born 1975), American video game journalist and ... rare fatal neurodegenerative disease This page lists people with the surname Gerstmann. If an internal link intending to refer ... musician Josef Gerstmann (1887-1969), Austrian neurologist Louis Gerstman (1930-1992), ...
Gerstmann syndrome - Wikipedia
It is named after Jewish Austrian-born American neurologist Josef Gerstmann. Gerstmann syndrome is characterized by four ... There are few reports of the syndrome, sometimes called developmental Gerstmann syndrome, in children. The cause is not known. ... "What ever happened to developmental Gerstmanns syndrome? Links to other pediatric, genetic, and neurodevelopmental syndromes ... Gerstmann syndrome is typically associated with damage to the inferior parietal lobule of the dominant hemisphere. It is ...
Gerstmann Syndrome | Eye Patient
Gerstmann Syndrome - Symptoms, Causes, Treatment
GS is also referred as the developmental Gerstmann syndrome or the Gerstmann tetrad ... Gerstmanns syndrome abbreviated as GS is also referred as the developmental Gerstmann syndrome or the Gerstmann tetrad, which ... Symptoms of Gertsmanns Syndrome. Gerstmanns syndrome is being specifically present and characterized by the loss of four ... gerstmann syndrome Standard Therapies, Investigational Therapies at https://rarediseases.org/rare-diseases/gerstmann-syndrome/ ...
Teaching NeuroImages: Gerstmann Syndrome in a Pediatric Patient with a Dominant Parietal Pleomorphic Xanthroastrocytoma
Gerstmann Syndrome in a Pediatric Patient with a Dominant Parietal Pleomorphic Xanthroastrocytoma. PubMed, SCI, Scopus, ESCI, ... Teaching NeuroImages: Gerstmann Syndrome in a Pediatric Patient with a Dominant Parietal Pleomorphic Xanthroastrocytoma. ... Teaching NeuroImages: Gerstmann Syndrome in a Pediatric Patient with a Dominant Parietal Pleomorphic Xanthroastrocytoma. ... Rusconi E. Gerstmann syndrome: historic and current perspectives. Handb Clin Neurol 151 (2018): 395-411. ...
Learning Disabilities: MedlinePlus
Gerstmanns Syndrome (National Institute of Neurological Disorders and Stroke) * What Are Reading Disorders? (Eunice Kennedy ... 47,XYY syndrome: MedlinePlus Genetics (National Library of Medicine) * Aarskog-Scott syndrome: MedlinePlus Genetics (National ... Smith-Kingsmore syndrome: MedlinePlus Genetics (National Library of Medicine) * Triple X syndrome: MedlinePlus Genetics ( ...
Aphasia: Practice Essentials, Background, Pathophysiology
Gerstmanns syndrome. Arch Neurol. 1992 May. 49(5):445-7. [QxMD MEDLINE Link]. ... Classical aphasia syndromes (see Aphasia syndromes in History) include global, Broca, Wernicke, and conduction aphasia, as well ... The fiction of the Gerstmann syndrome. J Neurol Neurosurg Psychiatry. 1961. 24:961-991. ... Geschwind N. Disconnexion syndromes in animals and man. I. Brain. 1965 Jun. 88(2):237-94. [QxMD MEDLINE Link]. ...
Table 2 - Chronic Wasting Disease and Potential Transmission to Humans - Volume 10, Number 6-June 2004 - Emerging Infectious...
Prion Disease: Symptoms, Causes, Treatment, & Prevention
Gerstmann-Straussler-Scheinker syndrome (GSS). GSS is also inherited. Like FFI, its transmitted in a dominant manner. It ... Gerstmann-Straussler-Scheinker syndrome (GSS). Feline spongiform encephalopathy (FSE). Kuru. Transmissible mink encephalopathy ... Alien hand syndrome is a neurological condition in which a persons hand seems to have a mind of its own. Heres what causes it ... Gerstmann-Straussker-Scheinker disease. (2016).. https://rarediseases.info.nih.gov/diseases/7690/gerstmann-straussler-scheinker ...
agnosia - Symptoms, Treatments and Resources for agnosia
urofacial syndrome - Ontology Browser - Rat Genome Database
Genoa Syndrome German Syndrome geroderma osteodysplasticum Gerstmann syndrome Ghosal hematodiaphyseal syndrome Ghose Sachdev ... urofacial syndrome + A syndrome that is characterized by inverted facial expressions in association with a severe and early- ... Cerebellar Vermis Aplasia with Associated Features suggesting Smith-Lemli-Opitz Syndrome and Meckel Syndrome ... urofacial syndrome (DOID:0050816). Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (2) Squirrel: ( ...
Learning Disabilities
Gerstmann Syndrome; math anxiety; and number blindness; Non-verbl Learning Disability (NLD). ... A collection of symptoms that often occur together form a syndrome. Syndromes are given terms and are studied by scientists and ... Dyscalculia , Dyslexia , Dysgraphia , Auditory Processing Disorder , Autism , Aspergers Syndrome , Attention Deficit / ... Common syndromes that pose barriers to learning:. *. Dyscalculia: AKA Math Learning Disability (MLD); LD-Math; Specific ...
Dyscalculia - wikidoc
PubMed for id: 371881 - Search Results - PubMed
Infarct core | Radiology Reference Article | Radiopaedia.org
Gerstmann syndrome. *temporal lobe infarct. *occipital lobe infarct * alexia without agraphia syndrome: PCA ... inferior medial pontine syndrome (Foville syndrome): basilar artery * lateral pontine syndrome (Marie-Foix syndrome): basilar ... Cestan-Chenais syndrome. * hemimedullary syndrome (Reinhold syndrome). * lateral medullary stroke syndrome (Wallenberg syndrome ...
Neuropsychology | Neurology | Brain Function | Online Course
Viruses | Free Full-Text | Cellular Prion Protein: From Physiology to Pathology
A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP. J.Neurosci. 2009 ... Gerstmann-Sträussler-Scheinker syndrome (GSS), sporadic, familial, and variant forms of Creutzfeldt-Jakob disease (CJD) in ... Gerstmann-Sträussler-Scheinker syndrome [27]. The mice also spontaneously developed prion diseases, showing spongiform ... all showed the appearance of C1 by western blot analysis and no cerebellar syndrome (Figure 2). On the other hand, ΔE(32-121) ( ...
Dyscalculia - Wikipedia
This has been observed in individuals with Gerstmann syndrome, of which dyscalculia is one of constellation of symptoms. ... It is sometimes colloquially referred to as "math dyslexia", though this analogy is misleading as they are distinct syndromes.[ ... Dyscalculia has also been associated with Turner syndrome[12] and people who have spina bifida.[13] ...
NIH Researchers Discover How Prion Protein Damages Brain Cells | National Institutes of Health (NIH)
Book Review: Textbook of Neurointensive Care, 2nd edition
Germ cell tumors, Gerstmanns syndrome, gliomas, Giullain-Barre syndrome (GBS);. Hashimotos thyroiditis, hematologic disorders ... Ehler-Danlos syndrome, Ehrlichiosis, encephalitis, endocarditis, epilepsy, erythrocytosis, extrapyramidal disorders;. Fronto- ... Acute intermittent hemodialysis (IHD), acute ischemic stroke (AIS), acute respiratory distress syndrome (ARDS), Alzheimers ... heterotopic ossification, Hoffman twitching, homonymous hemianopia, Horners syndrome, hyperkalemia, hyponatremia, hypoxemia. ...
Browse | jns Journals
Subject area BSE - BfR
Browse | jns Journals
PrP Monoclonal Antibody (F89/160.1.5) (MA1-750)
Genetic Prion Disease
PRNP - wikidoc
Gerstmann-Sträussler-Scheinker syndrome - usually a change in codon 102 from proline to leucine[44] ... Collins S, McLean CA, Masters CL (2001). "Gerstmann-Straussler-Scheinker syndrome, fatal familial insomnia, and kuru: a review ... suggesting a new phenotype for Gerstmann-Straussler-Scheinker syndrome.[49][53] The same study proposed sequencing PRNP in ... Gerstmann-Sträussler-Scheinker syndrome, kuru, scrapie, transmissible mink encephalopathy, ungulate spongiform encephalopathy, ...
Scientific overview | Dementia Research Centre - UCL - University College London
Gerstmanns syndrome (acalculia, agraphia, finger agnosia, left/right disorientation), alexia, agraphia, acalculia and apraxia ... The PCA syndrome justifies an independent nosological status, but with Alzheimers disease as the most common underlying cause ... Balints syndrome in Alzheimers disease: specific disruption of the occipito-parietal visual pathway. Brain Res. 1989;493(2): ... Other focal posterior cortical syndromes The proposed diagnostic criteria for PCA (Mendez et al., 2002; Tang-Wai et al., 2004) ...
Tracking Longitudinal Change in Presymptomatic Genetic Prion Disease | Memory and Aging Center
Pathology
Gerstmann syndrome) · Motor function (developmental dyspraxia). Pervasive: Autism · Rett syndrome · Asperger syndrome. ... Unconjugated (Lucey-Driscoll syndrome, Gilberts syndrome, Crigler-Najjar syndrome) - Conjugated (Dubin-Johnson syndrome, Rotor ... Fovilles syndrome, Millard-Gubler syndrome, Lateral medullary syndrome, Webers syndrome, Lacunar stroke). ... Pre-excitation syndrome (Wolff-Parkinson-White, Lown-Ganong-Levine) - Long QT syndrome - Adams-Stokes syndrome - Cardiac arrest ...
Clinical profile of fatal familial insomnia: phenotypic variation in 129 polymorphisms and geographical regions | Journal of...
PEPSIC - pepsic.bvsalud.orgKuruCreutzfeldt-Jakob DDiseaseTransient GerstmannLesionsDevelopmental Gerstmann's syndromeAngular gyrusNeuropsychological disorderAgraphiaGerstmann'sAphasia1924GeneticAntiphospholipid syndromeNeurologistMyelodysplastic syndromeVariantDisorderArterialIncludeDiagnosisParietalStrokeEvaluationAphasicClinicalAspergerLiteratureDominantCasesBrainWithdrawalAspectCure
Kuru9
- CreutzfeldtJakob disease CJD GerstmannSträusslerScheinker syndrome GSS fatal familial insomnia FFI and kuru constitute major human prion disease phenotypes. (netlify.app)
- They can be sporadic (Jakob-Creutzfeldt disease [JCD]), genetic (genetic JCD, Gerstmann-Sträussler-Scheinker, and familial fatal insomnia), or acquired (kuru, variant JCD, and iatrogenic JCD). (thieme-connect.de)
- Other forms of human prion diseases include variant CJD, fatal familial insomnia, Gerstmann-Straussler-Scheinker Syndrome and Kuru. (nih.gov)
- The type of prion disease found in human can be classified into Creutzfeldt-Jakob Disease (CJD), Gerstmann-Straussler syndrome (GSS) and kuru. (wikibooks.org)
- Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. (nih.gov)
- There are TSEs of humans (Creutzfeld-Jacob disease, fatal familial insomnia, Gerstmann--Sträussler syndrome, Kuru) cows (bovine spongiform encephalopathy or mad cow disease), sheep and goats (scrapie), deer, elk, and moose (chronic wasting disease), and of a variety of other mammals. (virology.ws)
- Others include Kuru and Gerstmann Straussler Scheinker Syndrome . (targetwoman.com)
- the human diseases belonging to this group are creutzfeld-jakob disease, kuru, and gerstmann-straussler syndrome. (liverpool.ac.uk)
- it is a transmissible disease of the central nervous system similar to creutzfeldt-jakob disease (cjd), gerstmann-sträussler-scheinker syndrome (gss) and kuru in man, and, in animals, scrapie in sheep and goats, chronic wasting disease (cwd) in captive mule deer and elk of north america and transmissible mink encephalopathy (tme) of farm reared mink. (liverpool.ac.uk)
Creutzfeldt-Jakob D4
- The three major phenotypes of genetic prion disease are genetic Creutzfeldt-Jakob disease (gCJD), fatal familial insomnia (FFI), and Gerstmann-Sträussler-Scheinker (GSS) syndrome. (nih.gov)
- Abnormally conformed prion protein using aggregation assays (RT QuIC) is typically positive in genetic Creutzfeldt-Jakob disease (gCJD), but not always in FFI or Gerstmann-Sträussler-Scheinker syndrome (GSS). (nih.gov)
- There are three distinct familial prion disease: Familial Creutzfeldt-Jakob Disease (fCJD), Fatal Familial Insomnia (FFI) and Gerstmann-Sträussler-Scheinker disease (GSS). (cjdfoundation.org)
- Familial prion diseases, which have overlapping signs and symptoms, include familial Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker syndrome (GSS), and fatal familial insomnia (FFI). (nih.gov)
Disease4
- The disorder should not be confused with Gerstmann-Sträussler-Scheinker disease , a type of transmissible spongiform encephalopathy. (nih.gov)
- The disease course ranges from a few months in gCJD and FFI to a few (up to 4, and in rare cases up to 10) years in GSS syndrome. (nih.gov)
- Gerstmann-Sträussler-Scheinker disease (GSS) is a very rare, neurodegenerative brain disease. (cjdfoundation.org)
- A 23-year-old woman with Gerstmann-Straussler-Scheinker disease (GSS) was investigated by 1H-magnetic resonance spectroscopy (1H-MRS). She developed gait ataxic at 22 years. (indexindex.com)
Transient Gerstmann1
- Transient Gerstmann syndrome has been reported in parietal lobe epilepsy. (eyewiki.org)
Lesions3
- Pure alexia, another left sided lesion that does not result in agraphia, despite being next to the area where lesions cause Gerstmann syndrome. (wikipedia.org)
- Acquired Gerstmann syndrome is associated with lesions in the dominant (usually left) PARIETAL LOBE which involve the angular gyrus or subjacent white matter. (nih.gov)
- If you are more interested in reviewing the various syndromes seen with focal cortical lesions as opposed to basic neuroanatomy please check out the " Anatomic Syndromes " chapter. (nowyouknowneuro.com)
Developmental Gerstmann's syndrome2
- There are few reports of the syndrome, sometimes called developmental Gerstmann's syndrome , in children. (nih.gov)
- What ever happened to developmental Gerstmann's syndrome? (wikipedia.org)
Angular gyrus3
- Gerstmann's syndrome is a cognitive impairment that results from damage to a specific area of the brain known as the left parietal lobe in the region of the angular gyrus. (nih.gov)
- Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms that suggests the presence of a lesion usually near the junction of the temporal and parietal lobes at or near the angular gyrus. (wikipedia.org)
- Specifically, the angular gyrus (Brodmann area 39) has been implicated in many studies, and thus this condition is sometimes referred to as angular gyrus syndrome. (eyewiki.org)
Neuropsychological disorder1
- Gerstmann syndrome is a neuropsychological disorder characterized by the tetrad of agraphia (inability to write), acalculia (inability to perform mathematical calculations), finger agnosia (inability to name, discriminate, or identify fingers), and left-right disorientation (inability to distinguish left from right). (eyewiki.org)
Agraphia2
- Gerstmann syndrome is defined as a tetrad including agraphia, acalculia, finger agnosia, and right-left disorientation. (ogu.edu.tr)
- Other more specific language syndromes include aphemia, alexia with and without agraphia, and pure word deafness. (medscape.com)
Gerstmann's3
- There is no cure for Gerstmann's syndrome. (nih.gov)
- Consider participating in a clinical trial so clinicians and scientists can learn more about Gerstmann's syndrome and related disorders. (nih.gov)
- A lesion to this region can lead to Gerstmann's syndrome . (nowyouknowneuro.com)
Aphasia6
- In the case studies presented in the literature, it has been reported that Gerstmann syndrome usually appears as an incomplete tetrad of symptoms or accompanied by cognitive deficits including aphasia, alexia, apraxia and some perceptual disorders. (ogu.edu.tr)
- The treatment of a patient with aphasia depends on the cause of the aphasia syndrome. (medscape.com)
- Such related syndromes may coexist with aphasia or exist independently. (medscape.com)
- Left-handed individuals may develop aphasia after a lesion of either hemisphere, but the syndromes from left hemisphere injury may be milder or more selective than those seen in right-handed people, and they may recover better. (medscape.com)
- Subcortical aphasia syndromes are defined more by the anatomy of the lesion than by the language characteristics. (medscape.com)
- The presentations of the types of aphasia vary and overlap considerably, but recent studies of both stroke patients and of normal subjects undergoing functional brain imaging have supported the general classification of aphasia syndromes and the localizations of specific language functions. (medscape.com)
19242
- It was first described by Joseph Gerstmann in a 1924 case study of a 52-year-old woman who had a left-sided stroke presenting with the four cardinal signs, with some subsequent case reports reporting additional cognitive deficits. (eyewiki.org)
- See Gerstmann (1924) , except you can't because it's not available anywhere. (derangedphysiology.com)
Genetic2
- Case Report: Cancer spectrum and genetic characteristics of a de novo germline POLD1 p.L606M variant-induced polyposis syndrome. (cdc.gov)
- Mercies in Disguise: A Story of Hope, a Family's Genetic Destiny, and the Science That Rescued Them , by Gina Kolata: Given my interest in diseases caused by inherited genetic mutations, this book, which details the Baxley family's experience with Gerstmann-Sträussler-Scheinker syndrome (GSS), caught my eye. (janethewriter.com)
Antiphospholipid syndrome1
- Comorbid association of obstructive sleep apnea (OSA) and thrombotic primary antiphospholipid syndrome (tPAPS): A more severe phenotype? (cdc.gov)
Neurologist1
- It is named after Jewish Austrian-born American neurologist Josef Gerstmann. (wikipedia.org)
Myelodysplastic syndrome1
- Impact of single versus multiple spliceosome mutations on myelodysplastic syndrome. (cdc.gov)
Variant1
- Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome. (thieme-connect.de)
Disorder3
- It is classically considered a left-hemisphere disorder, although right-hemisphere damage has also been associated with components of the syndrome. (wikipedia.org)
- Developmental Gerstmann syndrome (DGS) has been reported in children as a type of learning disorder. (eyewiki.org)
- GSS or Gerstmann Straussler Scheinker Syndrome is a rare neurological disorder due to brain degeneration. (targetwoman.com)
Arterial1
- There is a list of "classical" stroke syndromes arranged by arterial territory, which one needs to commit to memory. (derangedphysiology.com)
Include1
- The nonperisylvian aphasias include anomic, transcortical motor, transcortical sensory, and mixed transcortical, sometimes called the isolation of the speech area syndrome. (medscape.com)
Diagnosis3
- A81.82 is a valid billable ICD10 diagnosis code for GerstmannStrausslerScheinker syndrome. (netlify.app)
- The time of evaluation of the patient is therefore important in the syndrome diagnosis. (medscape.com)
- Thus far, CICM have not expected their exam candidates to make this sort of diagnosis in the written papers, perhaps with the exception of Question 10.1 from the second paper of 2013 and Question 27 from the first paper of 2019, both of which asked about lateral medullary syndrome. (derangedphysiology.com)
Parietal1
- Gerstmann syndrome is typically associated with damage to the inferior parietal lobule of the dominant hemisphere. (wikipedia.org)
Stroke3
- citation needed] In adults, the syndrome may occur after a stroke. (wikipedia.org)
- The Internet Stroke Centre used to be an excellent summary of stroke syndromes, and was the main source for this summary. (derangedphysiology.com)
- It even had references to the studies which describe each specific stroke syndrome. (derangedphysiology.com)
Evaluation1
- Evaluation for Gerstmann syndrome begins with confirmation of the clinical findings. (eyewiki.org)
Aphasic1
- Many specific aphasic syndromes have been reported. (medscape.com)
Clinical2
- It is debated whether Gerstmann syndrome constitutes a distinct clinical entity with a specific neuroanatomical correlation. (eyewiki.org)
- Although all of the syndromes described later in this section have clinical and historical validity, they also have numerous limitations. (medscape.com)
Asperger3
- This Reading Room takes those 16th markets on one How to Be Yourself in a World That\'s Different: An Asperger\'s Syndrome Study Guide for Adolescents 2007. (computronic.com.ar)
- Posted on August , 2017 in The How to Be Yourself in a World That\'s Different: An Asperger\'s Syndrome that we always was from wavelengths is that trying SSL considerations, enough when they tell learning to run, was soon hard marketing. (computronic.com.ar)
- In the How to Be Yourself in a World That\'s Different: An Asperger\'s Syndrome Study Guide of GroupWise, this will Search evidence about the world of systematic neighborhoods, Inactive Mailboxes, Resources Accounts and not on. (computronic.com.ar)
Literature1
- There is significant debate in the scientific literature as to whether Gerstmann syndrome truly represents a unified, theoretically motivated syndrome. (wikipedia.org)
Dominant1
- This list includes dominant and non-dominant MCA infarction, medial and lateral medullary syndromes, anterior and posterior cerebral artery syndromes and the basilar artery syndrome. (derangedphysiology.com)
Cases1
- There are also cases of iatrogenic Gerstmann syndrome resulting from cerebral angiography. (eyewiki.org)
Brain2
- Attempts to recreate Gerstmann syndrome via electrical stimulation of the brain have only been successful by targeting multiple brain regions simultaneously. (eyewiki.org)
- The syndromes are broad phenotypes that may accompany different types of brain dysfunction, but they are useful because they provide a terminology to permit clinicians to communicate with one another regarding the patient. (medscape.com)
Withdrawal1
- Discontinuation of the drug then produces a withdrawal syndrome characterized by dysphoria - the opposite of euphoria - as nucleus accumbens activity declines below normal levels. (wikidoc.org)
Aspect1
- It is the most variable and least understood aspect of Gerstmann syndrome. (eyewiki.org)
Cure1
- vague][citation needed] There is no cure for Gerstmann syndrome. (wikipedia.org)
