Griffonia
Plant Lectins
Lectins
Rosales
Glycoconjugates
Histocytochemistry
Oligosaccharides
Carbohydrate Sequence
Impaired axonal regeneration by isolectin B4-binding dorsal root ganglion neurons in vitro. (1/2)
The subpopulation of dorsal root ganglion (DRG) neurons recognized by Griffonia simplicifolia isolectin B4 (IB4) differ from other neurons by expressing receptors for glial cell line-derived neurotrophic factor (GDNF) rather than neurotrophins. Additionally, IB4-labeled neurons do not express the laminin receptor, alpha7-integrin (Gardiner et al., 2005), necessary for optimal axonal regeneration in the peripheral nervous system. In cultures of dissociated DRG neurons of adult mice on laminin, robust spontaneous neurite outgrowth from IB4-negative neurons occurs and is strongly enhanced by previous axotomy. In contrast, IB4-labeled neurons show little neurite outgrowth and do not express GAP 43, even after axotomy or culture with GDNF. Moreover, growth of their axons through collagen gels is impaired compared with other DRG neurons. To determine whether the sparse neurite outgrowth of IB4-labeled neurons is attributable to lack of integrin expression, DRG cultures were infected with a herpes simplex 1 vector encoding alpha7-integrin, but its forced expression failed to promote neurite outgrowth in either IB4-labeled or other DRG neurons or in cultured adult retinal ganglion cells. Forced coexpression of both alpha7-integrin and GAP 43 also failed to promote neurite outgrowth in IB4-labeled neurons. In addition, cultured sciatic nerve segments were found to release much lower levels of GDNF, demonstrated by ELISA, than nerve growth factor. These findings together with their impaired intrinsic axonal regeneration capacity may contribute to the known vulnerability of the IB4-labeled population of DRG neurons to peripheral nerve injury. (+info)Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development. (2/2)
(+info)Griffonia is a genus of woody climbing shrubs in the legume family, Fabaceae. It is native to West and Central Africa. The most well-known species in this genus is Griffonia simplicifolia, which contains high levels of an alkaloid called 5-HTP (5-hydroxytryptophan) in its seeds. 5-HTP is a precursor to the neurotransmitter serotonin and has been used in supplements for conditions such as depression, anxiety, insomnia, and migraines. However, it's important to note that the use of Griffonia or 5-HTP supplements should be done under the supervision of a healthcare provider due to potential side effects and interactions with other medications.
Plant lectins are proteins or glycoproteins that are abundantly found in various plant parts such as seeds, leaves, stems, and roots. They have the ability to bind specifically to carbohydrate structures present on cell membranes, known as glycoconjugates. This binding property of lectins is reversible and non-catalytic, meaning it does not involve any enzymatic activity.
Lectins play several roles in plants, including defense against predators, pathogens, and herbivores. They can agglutinate red blood cells, stimulate the immune system, and have been implicated in various biological processes such as cell growth, differentiation, and apoptosis (programmed cell death). Some lectins also exhibit mitogenic activity, which means they can stimulate the proliferation of certain types of cells.
In the medical field, plant lectins have gained attention due to their potential therapeutic applications. For instance, some lectins have been shown to possess anti-cancer properties and are being investigated as potential cancer treatments. However, it is important to note that some lectins can be toxic or allergenic to humans and animals, so they must be used with caution.
Lectins are a type of proteins that bind specifically to carbohydrates and have been found in various plant and animal sources. They play important roles in biological recognition events, such as cell-cell adhesion, and can also be involved in the immune response. Some lectins can agglutinate certain types of cells or precipitate glycoproteins, while others may have a more direct effect on cellular processes. In some cases, lectins from plants can cause adverse effects in humans if ingested, such as digestive discomfort or allergic reactions.
I apologize for any confusion, but "Rosales" is not a medical term. It is a botanical term used in the classification of plants. Rosales is an order of flowering plants that includes roses, as well as many other plants such as apples, cherries, almonds, and strawberries. The plants in this group are characterized by having flowers with multiple stamens and styles. I hope this clarifies any confusion. If you have any medical terms you would like defined, please let me know!
Glycoconjugates are a type of complex molecule that form when a carbohydrate (sugar) becomes chemically linked to a protein or lipid (fat) molecule. This linkage, known as a glycosidic bond, results in the formation of a new molecule that combines the properties and functions of both the carbohydrate and the protein or lipid component.
Glycoconjugates can be classified into several categories based on the type of linkage and the nature of the components involved. For example, glycoproteins are glycoconjugates that consist of a protein backbone with one or more carbohydrate chains attached to it. Similarly, glycolipids are molecules that contain a lipid anchor linked to one or more carbohydrate residues.
Glycoconjugates play important roles in various biological processes, including cell recognition, signaling, and communication. They are also involved in the immune response, inflammation, and the development of certain diseases such as cancer and infectious disorders. As a result, understanding the structure and function of glycoconjugates is an active area of research in biochemistry, cell biology, and medical science.
Histochemistry is the branch of pathology that deals with the microscopic localization of cellular or tissue components using specific chemical reactions. It involves the application of chemical techniques to identify and locate specific biomolecules within tissues, cells, and subcellular structures. This is achieved through the use of various staining methods that react with specific antigens or enzymes in the sample, allowing for their visualization under a microscope. Histochemistry is widely used in diagnostic pathology to identify different types of tissues, cells, and structures, as well as in research to study cellular and molecular processes in health and disease.
Oligosaccharides are complex carbohydrates composed of relatively small numbers (3-10) of monosaccharide units joined together by glycosidic linkages. They occur naturally in foods such as milk, fruits, vegetables, and legumes. In the body, oligosaccharides play important roles in various biological processes, including cell recognition, signaling, and protection against pathogens.
There are several types of oligosaccharides, classified based on their structures and functions. Some common examples include:
1. Disaccharides: These consist of two monosaccharide units, such as sucrose (glucose + fructose), lactose (glucose + galactose), and maltose (glucose + glucose).
2. Trisaccharides: These contain three monosaccharide units, like maltotriose (glucose + glucose + glucose) and raffinose (galactose + glucose + fructose).
3. Oligosaccharides found in human milk: Human milk contains unique oligosaccharides that serve as prebiotics, promoting the growth of beneficial bacteria in the gut. These oligosaccharides also help protect infants from pathogens by acting as decoy receptors and inhibiting bacterial adhesion to intestinal cells.
4. N-linked and O-linked glycans: These are oligosaccharides attached to proteins in the body, playing crucial roles in protein folding, stability, and function.
5. Plant-derived oligosaccharides: Fructooligosaccharides (FOS) and galactooligosaccharides (GOS) are examples of plant-derived oligosaccharides that serve as prebiotics, promoting the growth of beneficial gut bacteria.
Overall, oligosaccharides have significant impacts on human health and disease, particularly in relation to gastrointestinal function, immunity, and inflammation.
A "carbohydrate sequence" refers to the specific arrangement or order of monosaccharides (simple sugars) that make up a carbohydrate molecule, such as a polysaccharide or an oligosaccharide. Carbohydrates are often composed of repeating units of monosaccharides, and the sequence in which these units are arranged can have important implications for the function and properties of the carbohydrate.
For example, in glycoproteins (proteins that contain carbohydrate chains), the specific carbohydrate sequence can affect how the protein is processed and targeted within the cell, as well as its stability and activity. Similarly, in complex carbohydrates like starch or cellulose, the sequence of glucose units can determine whether the molecule is branched or unbranched, which can have implications for its digestibility and other properties.
Therefore, understanding the carbohydrate sequence is an important aspect of studying carbohydrate structure and function in biology and medicine.
Glycoproteins are complex proteins that contain oligosaccharide chains (glycans) covalently attached to their polypeptide backbone. These glycans are linked to the protein through asparagine residues (N-linked) or serine/threonine residues (O-linked). Glycoproteins play crucial roles in various biological processes, including cell recognition, cell-cell interactions, cell adhesion, and signal transduction. They are widely distributed in nature and can be found on the outer surface of cell membranes, in extracellular fluids, and as components of the extracellular matrix. The structure and composition of glycoproteins can vary significantly depending on their function and location within an organism.
Griffonia
Griffonia simplicifolia
Cercidoideae
List of Fabaceae genera
N-Feruloylserotonin
Charaxes virilis
Charaxes cynthia
Charaxes plantroui
Charaxes etheocles
Charaxes cedreatis
List of MeSH codes (B06)
Marie-Théophile Griffon du Bellay
Exposition Universelle (1867)
Griffonia - Wikipedia
DyLight 649 Labeled Griffonia Simplicifolia IB4 GSL I - isolectin B4
Griffonia tessmannii (De Wild.) Compère | Plants of the World Online | Kew Science
Djibouti Griffonia Simplicifolia Seed suppliers and manufacturers
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Griffonia Simplicifolia (Slaapmutjeskruid): Feiten, Voordelen, Effecten, Dosering
1.What is the biological source of Griffonia?
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Griffonia, 60 capsules - Life Light - VitalAbo Online Shop Europe
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Product Brochures
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Griffonia Simplicifolia 5-HTP Extract - China - Griffonia Simplicifolia - Dried Plants - Ethnobotanical Items - Griffonia...
Simplicifolia Seed1
- Take a look at our suppliers and offers for Griffonia Simplicifolia Seed in Djibouti. (tridge.com)
Capsule1
- Each Capsule has 600mg Griffonia Seed extract In natural Pullulan capsules. (5greens.co.uk)
Serotonin4
- Griffonia simplicifolia is a natural source of serotonin and can naturally replace its lack. (fitoben.com)
- Griffonia simplicifolia naturally contains 5-HTP , a precursor of serotonin so it can make up for a deficiency of serotonin itself. (fitoben.com)
- Griffonia koju zovu i „prirodni Prozac", ali sasvim neopravdano jer ona sadrži anti-depresivni sastojak 5-HTP od koga telo pravi serotonin . (top-shoponline.com)
- Griffonia - The seed of the African Black Bean - is rich in L-5-hydroxytryptophan (5-HTP), which is converted into serotonin by the body in the brain. (encormed.at)
5HTP2
- HONGDA's Griffonia Seed Extract 5htp is widely used in the dietary supplement, pharmaceutical and food industries. (pure-plantextract.com)
- L-TRYPTOPHAN is een essentieel aminozuur en wordt met tussenstap - 5HTP - serotonine/melatonine. (pelincour.be)
Magnesium1
- Each component of the novel phytotherapic combination of Tanacethum, Parthenium, Griffonia, simpliciofila, and Magnesium (AURASTOP ® ) acts on a different target among the main mechanisms involved in the pathophysiology of migraine and of the aura itself: sensitization of trigeminal vascular system, central sensitization and activation of the migraine generator located in the brainstem, through glutammate and kynurenine pathways and the cortical spreading depression. (ommegaonline.org)
Baill2
- Griffonia comprises the following species: Griffonia physocarpa Baill. (wikipedia.org)
- Griffonia Baill. (wikipedia.org)
Tessmannii1
- Griffonia tessmannii (De Wild. (wikipedia.org)
Plants1
- Griffonia is a genus of central African flowering plants in the legume family, Fabaceae. (wikipedia.org)
Extract Capsules1
- We provide customized services for Griffonia Seed Extract, Griffonia Seed Extract Powder, Griffonia Seed Extract Capsules. (pure-plantextract.com)
Extracted from the seeds1
- 5-HTP is extracted from the seeds of the Griffonia Simplicifolia. (smartproduct.eu)
Appetite2
- Appetite suppressants can be natural, like green tea, glucomannan and Griffonia simplicifolia . (tuasaude.com)
- Griffonia Simplicifolia is a plant that can help to suppress appetite as it is high in 5-HTP. (tuasaude.com)
Shrub2
- Griffonia is a shrub. (herbpathy.com)
- Griffonia simplicifolia is a woody climbing shrub. (thisisafrica.me)
Africa2
- The Griffonia is a plant native of Africa, more specifically, it originates from the western countries, such as Ghana, Côte D'Ivoire and Togo. (fitoben.com)
- Griffonia Seed Extract is a natural product derived from the seeds of a plant native to Africa. (pure-plantextract.com)
Mood4
- Griffonia® is a natural remedy that promotes the maintenance of normal mood tone , relaxation and mental well-being . (fitoben.com)
- Griffonia for the maintenance of normal mood tone. (fitoben.com)
- 2 packs of Griffonia® , natural food supplement that favors the maintenance of a normal mood, relaxation and mental health. (fitoben.com)
- Whether you are looking to improve your sleep patterns, mood, or cognitive functioning, Griffonia Seed Extract 5-HTP is the perfect choice. (pure-plantextract.com)
Supplement1
- So, if you are looking for a premium quality supplement, Griffonia Seed Extract is the perfect choice. (pure-plantextract.com)
Plant1
- It's produced commercially from the seeds of an African plant known as Griffonia simplicifolia. (zombievapes.co.uk)
Source2
- The genus Griffonia was named by Henri Baillon in honour of his friend and fellow physician Marie-Théophile Griffon du Bellay, explorer of Gabon, pioneer in the study of sleeping sickness and also of the African entheogen Iboga, source of the alkaloid ibogaine. (wikipedia.org)
- 1.What is the biological source of Griffonia? (jeevaorganic.com)
Effective1
- The griffonia seeds also prove effective in situations where it is difficult to control the impulse of hunger, especially that aimed at sweets and carbohydrates. (spezieriepalazzovecchio.it)
Support1
- At Griffonia Seed Extract , we are dedicated to providing superior technical support and services for our customers. (pure-plantextract.com)
Complex3
- Uniek: 5-HTP complex met 5-hydroxytryptofaan van het beste 98% Griffonia Simplicifolia-extract. (pelincour.be)
- waternavelkruid), L-tryptofaan en L-tyrosine, evenals vitaminen B6 en B12 tot het perfecte serotonine-melatonine-complex. (pelincour.be)
- L-Tyrosine is de bouwsteen van de eveneens belangrijke neurotransmitter dopamine en maakt het complex ideaal. (pelincour.be)
Products2
- The production process of HONGDA Griffonia Seed Extract is strictly controlled by the quality management system, making sure that all the products meet the industry standards. (pure-plantextract.com)
- As a professional Griffonia Seed Extract supplier, we guarantee that our products are of the highest quality, and we strive to provide the best customer service. (pure-plantextract.com)
Quality3
- Griffonia Seed Extract Powder is carefully processed to ensure that it meets the highest quality standards. (pure-plantextract.com)
- HONGDA provides Griffonia Seed Extract with superior quality as a professional Griffonia Seed Extract Powder supplier. (pure-plantextract.com)
- At HONGDA, we are committed to providing our customers with the highest quality Griffonia Seed Extract Powder. (pure-plantextract.com)
Specific1
- Griffonia simplicifolia-II (GS-II) is a lectin specific to terminal α/ßGlcNAc residues. (bvsalud.org)
Improve1
- Griffonia and Gymnema to improve the control of hunger. (fitoben.com)
Extract10
- Natural extract of Griffonia simplicifolia 350 mg (including 5-HTP 105 mg) . vitamin B3 9mg (50% RDA), B6 1mg (50% RDA). (activpharma.com)
- Griffonia seed extract can be made into capsules, troche and granule as healthy food and drug. (naturactive.cn)
- Griffonia Seed Extract may help relieve anxiety and extract controls appetite. (nutriavenue.com)
- Our Melatonin Complex provides 1.9mg of Melatonin per capsule, with Griffonia Seed Extract, Magnesium and B6. (zenement.com)
- Griffonia Complex, with L-Tryptophan, Saffron Extract. (zenement.com)
- One of the substances that can assist with this is Griffonia extract, also known as 5-HTP. (wanderingminds.world)
- You can buy supplements containing Griffonia extract, such as via Amazone.com. (wanderingminds.world)
- Acetar is a leading China griffonia seed extract bulk manufacturer, supplier and exporter. (acetarbiotech.com)
- Adhering to the pursuit of perfect quality of products, so that our griffonia seed extract bulk have been satisfied by many customers. (acetarbiotech.com)
- If you are interested in our griffonia seed extract bulk services, you can consult us now, we will reply to you in time! (acetarbiotech.com)
Vahl1
- Griffonia simplicifolia (M.Vahl ex DC. (wikipedia.org)
Fabaceae1
- Griffonia is a genus of central African flowering plants in the legume family, Fabaceae. (wikipedia.org)
Puritan's Pride1
- Puritan's Pride foloseste 5-HTP natural, extras din semintele plantei Griffonia simplicifolia. (go-vita.ro)
Hydroxytryptophan1
- Viridian Nutritions 5-hydroxytryptophan (5-HTP) is sourced from sustainable Griffonia symplicifolia seeds. (thehealthworkshop.co.uk)
Supplements1
- One of the supplements gaining popularity is 5-HTP, derived from the Griffonia plant. (wanderingminds.world)
Genus2
- The genus Griffonia was named by Henri Baillon in honour of his friend and fellow physician Marie-Théophile Griffon du Bellay, explorer of Gabon, pioneer in the study of sleeping sickness and also of the African entheogen Iboga, source of the alkaloid ibogaine. (wikipedia.org)
- Compère The genus Griffonia, as well as the type, G. physocarpa, were first described and published in Adansonia 6: 188. (wikipedia.org)
Natural2
- The natural supplement 5-HTP is derived from the seeds of the African Griffonia Simplicifolia plant. (wanderingminds.world)
- Natural Medicines Comprehensive Database (La Base Exhaustiva de Datos de Medicamentos Naturales) clasifica la eficacia, basada en evidencia científica, de acuerdo a la siguiente escala: Eficaz, Probablemente Eficaz, Posiblemente Eficaz, Posiblemente Ineficaz, Probablemente Ineficaz, Ineficaz, e Insuficiente Evidencia para Hacer una Determinación. (medlineplus.gov)
ADHD1
- In various Facebook groups for people with ADHD, including the Wandering Minds Community, I see questions about Griffonia, or 5-HTP, and people seeking others' experiences with it. (wanderingminds.world)
Naturally1
- Source Naturals 5-HTP is naturally derived from the seeds of the African plant Griffonia simplicifolia. (giftespot.com)
View1
- You can view Griffonia Simplicifolia Seed's global data or select another country for Griffonia Simplicifolia Seed from below. (tridge.com)
Summary1
- Browse the total import/export value of Griffonia Simplicifolia Seed in Morocco with a summary of price and production data. (tridge.com)
African1
- contains 5-HTP, dervied from Griffonia simplicifolia, a West African plant. (ultimatefatburner.com)
Discover2
- Discover export data of Griffonia Simplicifolia Seed from Morocco. (tridge.com)
- Discover import data of Griffonia Simplicifolia Seed to Morocco. (tridge.com)