A neoplasm derived from blood vessels, characterized by numerous prominent endothelial cells that occur singly, in aggregates, and as the lining of congeries of vascular tubes or channels. Hemangioendotheliomas are relatively rare and are of intermediate malignancy (between benign hemangiomas and conventional angiosarcomas). They affect men and women about equally and rarely develop in childhood. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1866)
A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have "borderline" aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)
Rapidly growing vascular lesion along the midline axis of the neck, upper trunk, and extremities that is characterized by CONSUMPTION COAGULOPATHY; THROMBOCYTOPENIA; and HEMOLYTIC ANEMIA. It is often associated with infantile Kaposiform HEMANGIOENDOTHELIOMA and other vascular tumors such as tufted ANGIOMA.
A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)
Neoplasms composed of vascular tissue. This concept does not refer to neoplasms located in blood vessels.
Neoplasms located in the vasculature system, such as ARTERIES and VEINS. They are differentiated from neoplasms of vascular tissue (NEOPLASMS, VASCULAR TISSUE), such as ANGIOFIBROMA or HEMANGIOMA.
A vascular anomaly due to proliferation of BLOOD VESSELS that forms a tumor-like mass. The common types involve CAPILLARIES and VEINS. It can occur anywhere in the body but is most frequently noticed in the SKIN and SUBCUTANEOUS TISSUE. (from Stedman, 27th ed, 2000)
The bones of the upper and lower LEG. They include the PELVIC BONES.
Unbroken cellular lining (intima) of the lymph vessels (e.g., the high endothelial lymphatic venules). It is more permeable than vascular endothelium, lacking selective absorption and functioning mainly to remove plasma proteins that have filtered through the capillaries into the tissue spaces.
Pathological processes of the inner ear (LABYRINTH) which contains the essential apparatus of hearing (COCHLEA) and balance (SEMICIRCULAR CANALS).
Tumors or cancer of any part of the hearing and equilibrium system of the body (the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR).
A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without amputation.
Tumors or cancer of the LIVER.
Spinal neoplasms are abnormal growths or tumors that develop within the spinal column, which can be benign or malignant, and originate from cells within the spinal structure or spread to the spine from other parts of the body (metastatic).
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
A group of twelve VERTEBRAE connected to the ribs that support the upper trunk region.

Expression of L-selectin ligands by transformed endothelial cells enhances T cell-mediated rejection. (1/119)

Recent immunohistochemical studies have suggested that L-selectin ligands may be implicated in the infiltration of tumors and rejected transplants by lymphocytes. In the present study, polyoma-middle T Ag-transformed endothelial cells (H.end), which typically form in vivo immunogenic vascular tumors resembling Kaposi's sarcoma, were engineered to express L-selectin ligands by stable transfection with a cDNA encoding alpha(1,3/4)-fucosyltransferase (H.endft). The ability of these cells to form tumors in the s.c. tissues of normal and immunocompromised mice was then compared with that of H.end cells transfected with the hygromycin-resistance vector only (H. endhygro). H.endhygro cells rapidly formed local and metastatic tumors in normal syngeneic mice, leading to death within 2-3 mo postinjection. By contrast, tumors derived from H.endft cells displayed a slower rate of growth, an absence of metastasis, and marked lymphocyte infiltration. Animals bearing these tumors survived for a significantly longer duration than animals injected with H.endhygro cells. Alternatively, H.endft and H.endhygro cells formed tumors with comparable aggressiveness in immunocompromised mice, resulting in animal death within 3 wk of injection. H.endft but not H.endhygro cells supported L-selectin-dependent adhesion and cytolytic T cell activity in vitro. Taken together, our observations indicate that the in situ expression of fucosyltransferase may significantly influence the cellular immune response in endothelioma tumors. These results may be relevant in understanding the development of vascular opportunistic tumors such as Kaposi's sarcoma.  (+info)

In vivo gene therapy with interleukin-12 inhibits primary vascular tumor growth and induces apoptosis in a mouse model. (2/119)

Interleukin-12 is proposed to have anti-neoplastic activity on the basis of both its anti-angiogenic and immunologic effects. Gene gun therapy with interleukin-12 cDNA into the peritumoral area of immunocompetent 129/J mice with life-threatening primary vascular tumors reduced tumor volume 7.5-fold and almost tripled the duration of mouse survival, in contrast with luciferase-bombarded control mice. Epidermal expression of mouse interleukin-12 elevated tumoral and serum levels of interferon-gamma and tumor necrosis factor-alpha, increased the tumoral populations of T lymphocyte and natural killer cells, and induced tumor apoptosis. Gene transfer of interleukin-12 had little effect on tumor volumes and survival of tumor-bearing athymic nude mice, emphasizing the requirement for T cell directed cellular immunity. Peritumoral gene gun introduction of interleukin-12 may be a novel, cost-effective approach to limit the growth and associated mortality of life-threatening tumors.  (+info)

Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene. (3/119)

The middle T antigen of murine Polyomavirus (PymT) rapidly transforms endothelial cells leading to vascular malformations reminiscent of endothelial tumors or hemangiomas. Flk-1, a receptor tyrosine kinase which is activated upon binding of its ligand VEGF, is predominantly expressed in endothelial cells and essential for the formation of blood vessels since absence of Flk-1 prevents the development of mature endothelial cells in mice and in ES-cell differentiation experiments. To investigate the role of Flk-1 in PymT-induced vascular tumor formation, we studied the expression of Flk-1 and VEGF in PymT-transformed endothelial cells (Endothelioma cells, END. cells). The receptor and its ligand were both expressed in END. cells suggesting that a VEGF/Flk-1 autocrine loop might be causally involved in the formation of vascular tumors. To test this hypothesis, ES cells lacking Flk-1 were generated and the transforming potential of PymT was analysed after in vitro differentiation. Flk-1(-/-) END. cell lines were established which are morphologically identical to flk-1(+/+) END. cells and which express several markers characteristic for endothelial cells. This result suggests that PymT functionally replaces the requirement of Flk-1 in expansion and/or survival of endothelial progenitor cells. Therefore, flk-1(-/-) END. cells provide a powerful tool to dissect the downstream signaling pathways of Flk-1.  (+info)

The generation of endostatin is mediated by elastase. (4/119)

Endostatin, a potent inhibitor of angiogenesis and tumor growth, is a COOH-terminal fragment of collagen XVIII derived through cleavage of an Ala-His linkage by an as yet unidentified endostatin-processing enzyme. Endostatin was originally isolated from the conditioned medium of hemangioendothelioma (EOMA) cells. By investigating the processing of collagen XVIII to endostatin by EOMA cells, we show here that the generation of endostatin can be mediated by an elastase activity. We also show that several members of the elastase family can act as an endostatin-processing enzyme by specifically cleaving the Ala-His linkage and releasing endostatin from a precursor molecule. We further suggest that the generation of endostatin from collagen XVIII is at least a two-step process, involving a metal-dependent early step and an elastase activity-dependent final step.  (+info)

Hemangioendothelioma of the parotid gland in infants: sonography and correlative MR imaging. (5/119)

BACKGROUND AND PURPOSE: Hemangioendothelioma is the most common parotid gland tumor of childhood, and is diagnosed on clinical grounds, supported by imaging findings. Previous work has suggested that MR is the best imaging technique for assessment of parotid hemangioendothelioma. Demonstration of a reliable sonographic appearance would reduce the need for MR imaging in infants with this lesion. METHODS: We performed high-frequency sonography (including color Doppler and power Doppler imaging) in three patients, each with a diagnosis of parotid hemangioendothelioma confirmed by clinical follow-up. Two patients were also examined with MR imaging and labeled red cell scintigraphy. RESULTS: All sonographic studies showed a homogeneous mass enlarging and replacing most or all of the visualized parotid gland, with a lobular internal structure, fine echogenic internal septations, and a mildly lobulated contour. Color Doppler and power Doppler imaging showed extremely high vascularity within the mass. Correlative MR images in two infants showed a well-defined lesion with uniform intense contrast enhancement. Labeled red cell scintigraphy showed a well-defined area of intense activity. CONCLUSION: In the presence of a typical clinical history, sonography and clinical follow-up alone may prove to be sufficient for safe management of parotid hemangioendothelioma. MR imaging or labeled red cell scintigraphy may only be required if the sonographic features are atypical. These findings require confirmation in a larger series of patients.  (+info)

Vascular endothelial growth factor receptor-3 (VEGFR-3): a marker of vascular tumors with presumed lymphatic differentiation, including Kaposi's sarcoma, kaposiform and Dabska-type hemangioendotheliomas, and a subset of angiosarcomas. (6/119)

Recently, a novel monoclonal antibody to vascular endothelial growth factor receptor 3 (VEGFR-3), a tyrosine kinase receptor expressed almost exclusively by lymphatic endothelium in the adult, has been shown to react with a small number of cases of Kaposi's sarcoma (KS) and cutaneous lymphangiomas. We sought to extend these studies to a large number of well-characterized vascular neoplasms to evaluate diagnostic uses of this antibody and to determine whether it defines them in a thematic fashion. Formalin-fixed, paraffin-embedded sections from 70 vascular tumors were immunostained with antibodies to VEGFR-3 von Willebrand factor (vWF), and CD31. Anti-VEGFR-3 was positive in 23 of 24 KS, 8 of 16 angiosarcomas (AS), 6 of 6 kaposiform hemangioendotheliomas, 4 of 4 Dabska tumors, and 2 of 13 hemangiomas. Positively staining angiosarcomas were characterized either by a prominent lymphocytic component, a hobnail endothelial cell similar to that encountered in the Dabska tumor, or spindled areas resembling KS. No VEGFR-3 expression was noted in any cases of epithelioid hemangioendothelioma, pyogenic granuloma, littoral angioma, or stasis dermatitis. vWF expression was seen in 10 of 13 KS; 13 of 14 AS; 4 of 5 kaposiform hemangioendotheliomas; and all Dabska tumors, hemangiomas, lymphangiomas, epithelioid hemangioendotheliomas, vascular malformations, stasis dermatitis, and splenic littoral angiomas. CD31 expression was present in 12 of 13 KS, 13 of 14 AS, and in all other cases. Expression of VEGFR-3 is a very sensitive marker of KS, kaposiform, and Dabska-type hemangioendotheliomas, suggesting that all show at least partial lymphatic endothelial differentiation. Expression of VEGFR-3 does not reliably discriminate KS from AS. However, the expression of VEGFR-3 by certain AS having Kaposi-like areas, a prominent lymphocytic infiltrate, or hobnail endothelium may define subset(s) having phenotypic, if not pathogenetic and biologic, differences.  (+info)

Sedation for intractable distress of a dying patient: acute palliative care and the principle of double effect. (7/119)

Shortly before his death in 1995, Kenneth B. Schwartz, a cancer patient at Massachusetts General Hospital (MGH), founded the Kenneth B. Schwartz Center at MGH. The Schwartz Center is a nonprofit organization dedicated to supporting and advancing compassionate health care delivery, which provides hope to the patient, support to caregivers, and encourages the healing process. The Center sponsors the Schwartz Center Rounds, a monthly multidisciplinary forum where caregivers reflect on important psychosocial issues faced by patients, their families, and their caregivers, and gain insight and support from fellow staff members. The case presented is of a young man dying of recurrent epithelioid hemangioendothelioma, distressed with stridor and severe pain, whose poorly controlled symptoms were successfully treated with an infusion of propofol, titrated to provide effective comfort in the last few hours of the patient's life. The tenet of double effect, which allows aggressive treatment of suffering in spite of foreseeable but unintended consequences, is reviewed. The patient's parents were invited and contributed to the Rounds, providing compelling testimony to the power of the presence of clinicians at the time of death and the importance of open communication about difficult ethical issues.  (+info)

Treatment options for other hepatic malignancies. (8/119)

1. Resection rates for cholangiocarcinoma (unrelated to primary sclerosing cholangitis) have increased to 54% to 79%, and the subsequent 5-year survival rates are 24% to 31%. 2. Multimodality approaches involving various combinations of chemotherapy, irradiation, and surgery increasingly are being used to treat cholangiocarcinoma. 3. The role of liver transplantation in the management of cholangiocarcinoma is limited by the perception that it is inappropriate to use scarce organs when 5-year survival rates are 25%. 4. Liver transplantation is an important intervention in patients with tumors that remain unresectable after chemotherapy. The role of liver transplantation in patients with extrahepatic disease that responds to chemotherapy is controversial. Careful timing of surgery is required to avoid secondary drug resistance. 5. Liver transplantation has been successfully applied to a range of rare hepatic malignancies, but small numbers preclude strong recommendations on the appropriateness of this practice.  (+info)

Hemangioendothelioma is a rare type of vascular tumor, which means it arises from the endothelial cells that line the blood vessels. It can occur in various parts of the body, but it most commonly involves the soft tissues and bones. Hemangioendotheliomas are often classified as borderline malignant tumors because they can behave either indolently (like a benign tumor) or aggressively (like a malignant tumor), depending on their specific type and location.

There are several subtypes of hemangioendothelioma, including:

1. Epithelioid hemangioendothelioma: This subtype typically affects young adults and can involve various organs, such as the liver, lungs, or soft tissues. It tends to have a more indolent course but can metastasize in some cases.
2. Kaposiform hemangioendothelioma: This is an aggressive subtype that usually occurs in infants and children. It often involves the skin and soft tissues, causing local invasion and consumptive coagulopathy (Kasabach-Merritt phenomenon).
3. Retiform hemangioendothelioma: A rare and low-grade malignant tumor that typically affects the skin and subcutaneous tissue of adults. It has a favorable prognosis with a low risk of metastasis.
4. Papillary intralymphatic angioendothelioma (PILA): This is a rare, slow-growing tumor that usually occurs in the head and neck region of children and young adults. It has an excellent prognosis with no reported cases of metastasis or recurrence after complete surgical resection.

Treatment for hemangioendotheliomas typically involves surgical excision when possible. Other treatment options, such as radiation therapy, chemotherapy, or targeted therapies, may be considered depending on the tumor's location, size, and behavior. Regular follow-up is essential to monitor for potential recurrence or metastasis.

Epithelioid Hemangioendothelioma is a rare type of vascular tumor that can develop in various parts of the body, such as the liver, lungs, bones, and soft tissues. It is characterized by the abnormal growth of endothelial cells, which line the interior surface of blood vessels.

Epithelioid Hemangioendothelioma is classified as a borderline malignant tumor, meaning it has the potential to behave in a benign or malignant manner. The tumor typically grows slowly and may remain localized for an extended period, but it can also metastasize (spread) to other parts of the body.

The epithelioid variant of Hemangioendothelioma is named for its distinctive appearance under a microscope. The tumor cells are large and have an epithelial-like morphology, which means they resemble the cells that make up the outer layer of the skin and other organs.

Clinical presentation and management of Epithelioid Hemangioendothelioma depend on the location and extent of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up is essential to monitor for any signs of recurrence or progression.

Kasabach-Merritt syndrome (KMS) is a rare but serious condition characterized by the combination of a large hemangioma or tufted angioma (benign vascular tumors) with severe thrombocytopenia (low platelet count) and consumptive coagulopathy (a disorder of blood clotting).

The syndrome is named after the two physicians who first described it in 1940. It primarily affects infants, with about 70% of cases diagnosed before the age of one month.

In KMS, the hemangioma or tufted angioma grows rapidly and becomes a consumptive coagulopathy due to platelet trapping within the lesion, leading to profound thrombocytopenia. This can result in bleeding complications, which can be life-threatening if not promptly treated.

The treatment of KMS typically involves a combination of medical management (such as corticosteroids, interferon, and vincristine) and surgical intervention to remove the hemangioma or tufted angioma. In some cases, embolization of the lesion may also be considered.

Hemangiosarcoma is a type of cancer that arises from the cells that line the blood vessels (endothelial cells). It most commonly affects middle-aged to older dogs, but it can also occur in cats and other animals, as well as rarely in humans.

This cancer can develop in various parts of the body, including the skin, heart, spleen, liver, and lungs. Hemangiosarcomas of the skin tend to be more benign and have a better prognosis than those that arise internally.

Hemangiosarcomas are highly invasive and often metastasize (spread) to other organs, making them difficult to treat. The exact cause of hemangiosarcoma is not known, but exposure to certain chemicals, radiation, and viruses may increase the risk of developing this cancer. Treatment options typically include surgery, chemotherapy, and/or radiation therapy, depending on the location and stage of the tumor.

A neoplasm of vascular tissue is an abnormal growth or mass of cells in the blood vessels or lymphatic vessels. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms, such as hemangiomas and lymphangiomas, are typically not harmful and may not require treatment. However, they can cause symptoms if they grow large enough to press on nearby organs or tissues. Malignant neoplasms, such as angiosarcomas, are cancerous and can invade and destroy surrounding tissue, as well as spread (metastasize) to other parts of the body. Treatment for vascular tissue neoplasms depends on the type, size, location, and stage of the growth, and may include surgery, radiation therapy, chemotherapy, or a combination of these.

Vascular neoplasms are a type of tumor that develops from cells that line the blood vessels or lymphatic vessels. These tumors can be benign (non-cancerous) or malignant (cancerous). Benign vascular neoplasms, such as hemangiomas and lymphangiomas, are usually harmless and may not require treatment unless they cause symptoms or complications. Malignant vascular neoplasms, on the other hand, are known as angiosarcomas and can be aggressive, spreading to other parts of the body and potentially causing serious health problems.

Angiosarcomas can develop in any part of the body but are most commonly found in the skin, particularly in areas exposed to radiation or chronic lymph edema. They can also occur in the breast, liver, spleen, and heart. Treatment for vascular neoplasms depends on the type, location, size, and stage of the tumor, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.

A hemangioma is a benign (noncancerous) vascular tumor or growth that originates from blood vessels. It is characterized by an overgrowth of endothelial cells, which line the interior surface of blood vessels. Hemangiomas can occur in various parts of the body, but they are most commonly found on the skin and mucous membranes.

Hemangiomas can be classified into two main types:

1. Capillary hemangioma (also known as strawberry hemangioma): This type is more common and typically appears during the first few weeks of life. It grows rapidly for several months before gradually involuting (or shrinking) on its own, usually within the first 5 years of life. Capillary hemangiomas can be superficial, appearing as a bright red, raised lesion on the skin, or deep, forming a bluish, compressible mass beneath the skin.

2. Cavernous hemangioma: This type is less common and typically appears during infancy or early childhood. It consists of large, dilated blood vessels and can occur in various organs, including the skin, liver, brain, and gastrointestinal tract. Cavernous hemangiomas on the skin appear as a rubbery, bluish mass that does not typically involute like capillary hemangiomas.

Most hemangiomas do not require treatment, especially if they are small and not causing any significant problems. However, in cases where hemangiomas interfere with vital functions, impair vision or hearing, or become infected, various treatments may be considered, such as medication (e.g., corticosteroids, propranolol), laser therapy, surgical excision, or embolization.

The lower extremity, also known as the lower limb, consists of the bones that make up the leg and foot. In humans, these bones include:

1. Femur: This is the thigh bone, and it is the longest and strongest bone in the human body.
2. Patella: Also known as the kneecap, this is a small triangular bone located at the front of the knee joint.
3. Tibia: This is the larger of the two bones in the lower leg, also known as the shin bone.
4. Fibula: This is the smaller of the two bones in the lower leg, located on the lateral side of the tibia.
5. Tarsal bones: These are seven small bones located in the foot, which articulate with the tibia and fibula to form the ankle joint.
6. Metatarsal bones: These are five long bones located in the midfoot, which connect to the phalanges (toes) at one end and the tarsal bones at the other.
7. Phalanges: These are fourteen small bones located in the toes, similar in structure to the phalanges in the fingers of the hand.

Together, these bones provide support, stability, and mobility to the lower extremity, allowing for activities such as walking, running, and jumping.

The endothelium is a thin layer of cells that lines the interior surface of blood vessels and lymphatic vessels. The lymphatic endothelium, specifically, is the type of endothelial cell that forms the walls of lymphatic vessels. These vessels are an important part of the immune system and play a crucial role in transporting fluid, waste products, and immune cells throughout the body.

The lymphatic endothelium helps to regulate the movement of fluids and cells between the tissues and the bloodstream. It also contains specialized structures called valves that help to ensure the unidirectional flow of lymph fluid towards the heart. Dysfunction of the lymphatic endothelium has been implicated in a variety of diseases, including lymphedema, inflammation, and cancer metastasis.

Labyrinth diseases refer to conditions that affect the inner ear's labyrinth, which is the complex system of fluid-filled channels and sacs responsible for maintaining balance and hearing. These diseases can cause symptoms such as vertigo (a spinning sensation), dizziness, nausea, hearing loss, and tinnitus (ringing in the ears). Examples of labyrinth diseases include Meniere's disease, labyrinthitis, vestibular neuronitis, and benign paroxysmal positional vertigo. Treatment for these conditions varies depending on the specific diagnosis but may include medications, physical therapy, or surgery.

Ear neoplasms refer to abnormal growths or tumors that occur in the ear. These growths can be benign (non-cancerous) or malignant (cancerous) and can affect any part of the ear, including the outer ear, middle ear, inner ear, and the ear canal.

Benign ear neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include exostoses, osteomas, and ceruminous adenomas. These types of growths are usually removed surgically for cosmetic reasons or if they cause discomfort or hearing problems.

Malignant ear neoplasms, on the other hand, can be aggressive and may spread to other parts of the body. Examples include squamous cell carcinoma, basal cell carcinoma, and adenoid cystic carcinoma. These types of tumors often require more extensive treatment, such as surgery, radiation therapy, and chemotherapy.

It is important to note that any new growth or change in the ear should be evaluated by a healthcare professional to determine the nature of the growth and develop an appropriate treatment plan.

Kaposi sarcoma (KS) is a type of cancer that causes abnormal growths in the skin, lymph nodes, or other organs. It is caused by the Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8). There are several forms of KS, including:

1. Classic KS: This form primarily affects older men of Mediterranean, Middle Eastern, or Ashkenazi Jewish descent. It tends to progress slowly and mainly involves the skin.
2. Endemic KS: Found in parts of Africa, this form predominantly affects children and young adults, regardless of their HIV status.
3. Immunosuppression-associated KS: This form is more aggressive and occurs in people with weakened immune systems due to organ transplantation or other causes.
4. Epidemic KS (AIDS-related KS): This is the most common form of KS, seen primarily in people with HIV/AIDS. The widespread use of antiretroviral therapy (ART) has significantly reduced its incidence.

KS lesions can appear as red, purple, or brown spots on the skin and may also affect internal organs such as the lungs, lymph nodes, or gastrointestinal tract. Symptoms vary depending on the location of the lesions but often include fever, fatigue, weight loss, and swelling in the legs or abdomen. Treatment options depend on the extent and severity of the disease and may involve local therapies (e.g., radiation, topical treatments), systemic therapies (e.g., chemotherapy, immunotherapy), or a combination of these approaches.

Blue toe syndrome, also known as acrocyanosis or digital ischemia, is a medical condition characterized by the bluish discoloration of the toes due to insufficient blood supply. This can occur due to various reasons such as chilblains, vasospasms, blood clots in the small arteries of the feet, or certain medications that affect blood flow. Prolonged exposure to cold temperatures, smoking, and underlying health conditions like Raynaud's disease, Buerger's disease, or autoimmune disorders can increase the risk of developing blue toe syndrome. Severe cases may require medical intervention such as medication, surgery, or lifestyle changes to improve blood flow and prevent tissue damage.

Liver neoplasms refer to abnormal growths in the liver that can be benign or malignant. Benign liver neoplasms are non-cancerous tumors that do not spread to other parts of the body, while malignant liver neoplasms are cancerous tumors that can invade and destroy surrounding tissue and spread to other organs.

Liver neoplasms can be primary, meaning they originate in the liver, or secondary, meaning they have metastasized (spread) to the liver from another part of the body. Primary liver neoplasms can be further classified into different types based on their cell of origin and behavior, including hepatocellular carcinoma, cholangiocarcinoma, and hepatic hemangioma.

The diagnosis of liver neoplasms typically involves a combination of imaging studies, such as ultrasound, CT scan, or MRI, and biopsy to confirm the type and stage of the tumor. Treatment options depend on the type and extent of the neoplasm and may include surgery, radiation therapy, chemotherapy, or liver transplantation.

Spinal neoplasms refer to abnormal growths or tumors found within the spinal column, which can be benign (non-cancerous) or malignant (cancerous). These tumors can originate in the spine itself, called primary spinal neoplasms, or they can spread to the spine from other parts of the body, known as secondary or metastatic spinal neoplasms. Spinal neoplasms can cause various symptoms, such as back pain, neurological deficits, and even paralysis, depending on their location and size. Early diagnosis and treatment are crucial to prevent or minimize long-term complications and improve the patient's prognosis.

A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.

The thoracic vertebrae are the 12 vertebrae in the thoracic region of the spine, which is the portion between the cervical and lumbar regions. These vertebrae are numbered T1 to T12, with T1 being closest to the skull and T12 connecting to the lumbar region.

The main function of the thoracic vertebrae is to provide stability and support for the chest region, including protection for the vital organs within, such as the heart and lungs. Each thoracic vertebra has costal facets on its sides, which articulate with the heads of the ribs, forming the costovertebral joints. This connection between the spine and the ribcage allows for a range of movements while maintaining stability.

The thoracic vertebrae have a unique structure compared to other regions of the spine. They are characterized by having long, narrow bodies, small bony processes, and prominent spinous processes that point downwards. This particular shape and orientation of the thoracic vertebrae contribute to their role in limiting excessive spinal movement and providing overall trunk stability.

Retiform hemangioendothelioma (also known as a "Hobnail hemangioendothelioma") is a low-grade angiosarcoma, first described in ... hemangioendothelioma) is crucial. The absence of urinary catecholamines supports the diagnosis of hemangioendothelioma. In ... Infantile hemangioendothelioma is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the ... Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. A complex ...
... (EHE) is a rare tumor, first characterized by Sharon Weiss and Franz Enzinger in 1982 that ... Although Epithelioid Hemangioendothelioma typically presents as a low-grade tumor, occasionally, eHAE presents as high grade ... "Epithelioid Hemangioendothelioma in children". Boston Children's Hospital. Archived from the original on August 18, 2017. https ... May 2001). "Translocation t(1;3)(p36.3;q25) is a nonrandom aberration in epithelioid hemangioendothelioma". Am J Surg Pathol. ...
Epithelioid hemangioendothelioma(1982) Kaposiform hemangioendothelioma(1993) Myxoid variant of malignant fibrous histiocytoma ( ... She is also well known for her seminal descriptions of multiple soft tissue tumors, such as epithelioid hemangioendothelioma ... Weiss, Sharon W.; Enzinger, F. M. (1982). "Epithelioid hemangioendothelioma a vascular tumor often mistaken for a carcinoma". ... Zukerberg, Lawrence R.; Nickoloff, Brian J.; Weiss, Sharon W. (1993). "Kaposiform Hemangioendothelioma of Infancy and Childhood ...
Levchenko T, Bratt A, Arbiser JL, Holmgren L (February 2004). "Angiomotin expression promotes hemangioendothelioma invasion". ...
As Carr discovers at the beginning of the film, she has a rare form of cancer called epithelioid hemangioendothelioma (EHE). In ... The film tells the story of Carr's battle with epithelioid hemangioendothelioma (EHE),Kris Carr has also written two books, ... "Pulmonary epithelioid hemangioendothelioma - rarity, diagnosis and treatment difficulties." Revista Portuguesa De Pneumologia [ ... epithelioid hemangioendothelioma (EHE). Despite its rarity, Carr is told that her tumors are not behaving aggressively, and so ...
"FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma". The American Journal of Surgical Pathology. 41 (5 ...
Croteau, SE; Gupta, D (September 2016). "The clinical spectrum of kaposiform hemangioendothelioma and tufted angioma". Seminars ... and Kaposiform Hemangioendothelioma". The American Journal of Dermatopathology. 40 (4): 231-239. doi:10.1097/DAD. ... "The importance of early diagnosis and treatment of kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon ...
2004). "A Case of Hypertrophic Osteoarthropathy Associated with Epithelioid Hemangioendothelioma". J Korean Med Sci. 19 (3): ...
Less frequently, it results from some malignant tumors, such as osteosarcoma, chondrosarcoma, and hemangioendothelioma.[ ...
The four most common types are: infantile hemangioma, congenital hemangioma, kaposiform hemangioendothelioma and pyogenic ... Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm that is locally aggressive but without metastatic potential. ...
PMID 14654573 "Seven-year Follow-up of Vertebral Excision and Reconstruction for Malignant Hemangioendothelioma of Bone." (May ...
For example, a study was able to demonstrate for the first time that a patient with a hemangioendothelioma of the liver with a ... "De Novo 13q13.3-21.31 deletion involving RB1 gene in a patient with hemangioendothelioma of the liver". Italian Journal of ...
August 2011). "A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different ...
... is usually caused by a hemangioendothelioma or other vascular tumor, often present at birth. Although ...
... and kaposiform hemangioendothelioma. Its unusual nature makes lymphangiomatosis (and Gorham's disease) a diagnostic and ...
... is also associated with a low grade form of cancer called retiform hemangioendothelioma (a low grade angiosarcoma). ...
On February 14, 2003, Carr was diagnosed with a rare Stage IV cancer called epithelioid hemangioendothelioma affecting her ...
... and malignant hemangioendothelioma". The Journal of Dermatology. 26 (9): 577-86. doi:10.1111/j.1346-8138.1999.tb02052.x. PMID ...
It was first found secreted in the media of non-metastasizing mouse cells from a hemangioendothelioma cell line in 1997 and was ...
... adenosarcoma Uterine high-grade leiomyosarcoma Uterine rhabdomyosarcoma Vascular tumors Epithelioid hemangioendothelioma are ...
Dabska-type hemangioendothelioma, hobnail hemangioendothelioma, malignant endovascular papillary angioendothelioma, papillary ... Kaposiform hemangioendothelioma (infantile kaposiform hemangioendothelioma) Kasabach-Merritt syndrome (hemangioma with ... Spindle cell hemangioendothelioma (spindle cell hemangioma) Spindle cell lipoma Sternal cleft Subungual exostosis Superficial ... hobnail hemangioendothelioma) Schwannoma (acoustic neuroma, neurilemmoma, neurinoma, neurolemmoma, Schwann cell tumor) Solitary ...
... or Ehe may refer to: Epithelioid hemangioendothelioma, a type of tumor Extreme helium star, a type of star Elective home ...
... hemangioendothelioma MeSH C04.557.645.375.370.380 - hemangioendothelioma, epithelioid MeSH C04.557.645.375.380 - hemangioma, ...
Kaolin pneumoconiosis Kaplan-Plauchu-Fitch syndrome Kaplowitz-Bodurtha syndrome Kaposi sarcoma Kaposiform hemangioendothelioma ...
... such as kaposiform hemangioendothelioma and tufted angioma. Interferon-alpha 2a and 2b, given by subcutaneous injection, has ...
... and thymic carcinoma Squamous-cell carcinoma of the lung AIDS-related cancers Kaposi sarcoma Epithelioid hemangioendothelioma ( ...
... pulmonary epithelioid hemangioendothelioma and pulmonary hyalinizing granuloma. Among his published works are: Liebow, A. A. ( ...
... benign M9130/1 Hemangioendothelioma, NOS Angioendothelioma Kaposiform hemangioendothelioma M9130/3 Hemangioendothelioma, ... NOS M9133/3 Epithelioid hemangioendothelioma, malignant Intravascular bronchial alveolar tumor M9135/1 Endovascular papillary ... hemangioma M9124/3 Kupffer cell sarcoma M9125/0 Epithelioid hemangioma Histiocytoid hemangioma M9130/0 Hemangioendothelioma, ... angioendothelioma Dabska tumor M9136/1 Spindle cell hemangioendothelioma Spindle cell angioendothelioma M9140/3 Kaposi's ...
HELLP syndrome Helmerhorst-Heaton-Crossen syndrome Helminthiasis HEM dysplasia Hemangioblastoma Hemangioendothelioma Hemangioma ...
Rarely, these lesions may be multiple or can occur as part of a syndrome with hemangiomas, epithelioid hemangioendothelioma, ...
Retiform hemangioendothelioma (also known as a "Hobnail hemangioendothelioma") is a low-grade angiosarcoma, first described in ... hemangioendothelioma) is crucial. The absence of urinary catecholamines supports the diagnosis of hemangioendothelioma. In ... Infantile hemangioendothelioma is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the ... Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. A complex ...
Epithelioid Hemangioendothelioma is a rare form of cancer that affects the blood vessels of an individual and has an unknown ... Epithelioid Hemangioendothelioma is a rare form of cancer that affects the blood vessels of an individual and has an unknown ... Epithelioid Hemangioendothelioma affects about 0.1 percent of the American population with an overall 5-year survival rate of ... More about Epithelioid Hemangioendothelioma Essay. *. Essay Unit 2 Assignment: Diagnostic Writers Response. 979 Words , 4 ...
... is a rare and aggressive vascular tumor that is ...
Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. Am J Surg Pathol. 2008 ... Mediastinal epithelioid hemangioendothelioma metastatic to lymph nodes and pleural fluid: report of a case. Diagn Cytopathol. ... "Hemangioendothelioma, Epithelioid" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ... Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment. Curr Treat Options Oncol. 2018 03 15; 19(4):19. ...
Epithelioid hemangioendothelioma. Epithelioid hemangioendothelioma is a rare, vascular, primary tumor of the liver that may ... epithelioid hemangioendothelioma, and angiosarcoma) may be difficult to differentiate from those of other benign or malignant ... epithelioid hemangioendothelioma, primary hepatic lymphoma, focal fatty infiltration and focal fatty sparing, lipoma, and ...
Foods for Epithelioid Hemangioendothelioma!. Aug 4, 2023. Introduction Foods for Epithelioid Hemangioendothelioma should be ...
Infantile hepatic hemangioendothelioma, abbreviated IHH, is a type of [[hemangioendothelioma]]. It is the most common ... title = Infantile hemangioendothelioma of the liver. , journal = Hepatology , volume = 20 , issue = 1 Pt 1 , pages = 39-45 , ... title = Infantile hepatic hemangioendothelioma: a clinicopathologic study in a Chinese population. , journal = World J ... title = Infantile hepatic hemangioendothelioma in comparison with hepatoblastoma in children: clinical and ultrasound features ...
Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon.. Kip R ... A 2-week-old infant developed respiratory failure due to a mediastinal Kaposiform hemangioendothelioma that was complicated by ... This case demonstrates that interferon can be used to treat infants with Kaposiform hemangioendothelioma in life-threatening ...
How are epithelioid hemangioendothelioma (EHE) and epithelioid angiosarcoma differentiated?. How are epithelioid angiosarcoma ... Vascular sarcomas of the pleura: Epithelioid hemangioendothelioma and angiosarcoma. Little is known of the genetics of EHE or ... The two major subtypes of primary vascular sarcomas of the pleura are epithelioid hemangioendothelioma (EHE) and angiosarcoma. ... Vascular sarcomas of the pleura: Epithelioid hemangioendothelioma and angiosarcoma. EHE tends to occur in middle-aged adults. ...
Mediastinal hemangioendothelioma: Case report and review of the literature. Respiratory Medicine Case Reports. 2017 Jan 1;22:19 ... Mediastinal hemangioendothelioma: Case report and review of the literature. Davide Patrini*, Laura Scolamiero, Reena Khiroya, ... Mediastinal hemangioendothelioma : Case report and review of the literature. in: Respiratory Medicine Case Reports. 2017 ; ... Mediastinal hemangioendothelioma: Case report and review of the literature. / Patrini, Davide; Scolamiero, Laura; Khiroya, ...
EHE - Epithelial Hemangio-Endothelioma, cancer driven by fusions of YAP or TAZ oncogenes with genes that encode transcription ... A rare sarcoma of soft tissues, known as the EHE - Epithelial Hemangio-Endothelioma is driven by the mutated versions of YAP or ...
Epithelioid hemangioendothelioma (EHE) of the thyroid is an extremely rare disease; only three cases have been reported in the ... Table 2 Summary of previously reported cases of epithelioid hemangioendothelioma (EHE) occurring in rare sites. Full size table ... Table 1 Characteristics of epithelioid hemangioendothelioma (EHE) in the liver, lungs, soft tissues, and bone (common ... Ono, M., Kasuga, Y., Uehara, T. et al. Epithelioid hemangioendothelioma of the thyroid: a case report. surg case rep 3, 18 ( ...
Return to Article Details Diagnosis of infantile hemangioendothelioma of the liver by triple phase computed tomography Download ...
Keywords: BAP1; Biphasic; CTNNB1 gene mutations; Desmoid; Desmoplastic; Epithelioid; Epithelioid hemangioendothelioma; Grading ...
Chareonsil, B.; Singhavechasakul, J.; and kattibhatthanapong, V. (1998) "Infantile hemangioendothelioma of the liver:A case ...
Hemangioendothelioma. Inflammatory myofibroblastic tumor. Intimal sarcoma. Kaposi sarcoma. Leiomyosarcoma. Liposarcoma. ...
Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature. ... Atypical retiform hemangioendothelioma arising in a patient with Milroy disease: a case report and review of the literature. / ... Atypical retiform hemangioendothelioma arising in a patient with Milroy disease : a case report and review of the literature. ... T1 - Atypical retiform hemangioendothelioma arising in a patient with Milroy disease. T2 - a case report and review of the ...
Epithelioid hemangioendothelioma (EHE) is a rare neoplasm originating from various organs. The clinical outcome mostly depends ... N2 - Epithelioid hemangioendothelioma (EHE) is a rare neoplasm originating from various organs. The clinical outcome mostly ... AB - Epithelioid hemangioendothelioma (EHE) is a rare neoplasm originating from various organs. The clinical outcome mostly ... abstract = "Epithelioid hemangioendothelioma (EHE) is a rare neoplasm originating from various organs. The clinical outcome ...
Hemangioendothelioma, lymphocyte rich, follicular dendritic cell, tumor Abstract. Hemangioendothelioma is a vascular tumor with ... Hemangioendothelioma with a Prominent Lymphoid Infiltrate Mimicking Follicular Dendritic Cell Tumor: Report of a Case Authors. ... Keyword: Hemangioendothelioma, lymphocyte rich, follicular dendritic cell, tumor. References Chan JKC. Proliferative Lesions of ... Epithelioid hemangioendothelioma. In: Fletcher CDM, et al. WHO Classification of Tumors: Pathology and Genetics of Tumors of ...
The lesion in this original case was a kaposiform hemangioendothelioma, not a classic infantile hemangioma. ... Massive congenital kaposiform hemangioendothelioma of the eyelid in a neonate. J Craniofac Surg. 2011 Nov. 22(6):e38-41. [QxMD ... Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon. J Pediatr ... Leg with a Kaposiform hemangioendothelioma, lesion associated with Kasabach-Merritt Syndrome. View Media Gallery ...
Hemangioendothelioma, Epithelioid / immunology * Hemangioendothelioma, Epithelioid / pathology * Hemangiopericytoma / ...
... Blood vessel hemangioendothelioma. Model Name. Blood vessel hemangioendothelioma. Strain. DD/He. Tumor Inducing ...
Metastatic Hepatic Epithelioid Hemangioendothelioma Treated with Olaratumab: A Falling Star Rising? Kyriazoglou A, Koutsoukos K ...
Hemangio-endothelioma of the Liver (Case Report)B. Zürcher , U. Caflisch , B. Hofer , A. Schärli , J. Laissue * Pathologisches ... The infantile hemangio-endothelioma (IHE) of the liver, a rare neoplasm, may lead the clinician and the surgeon to suspect the ...
Our team of liver specialists is committed to providing comprehensive care by partnering with families to care for each child - not just the disease. We work directly with other specialists throughout Childrens Mercy whenever needed in order to give children the best available care. We also coordinate with hepatology and transplant teams at the University of Kansas Medical Center to offer comprehensive care as our teenage patients transition to adulthood.. ...
Hemangioendothelioma Western France. Wed Nov 23, 2011 10:48 am. rbrasier. 0. Adenoid Cystic Carcinoma Sun Dec 04, 2011 9:55 pm ...
Bartonella species bacteremia in two patients with epithelioid hemangioendothelioma. J Clin Microbiol. 2011;49:4006-12. DOI ... hemangioendothelioma (30). In total, B. henselae DNA was detected in 47 cases (5,30-33); B. koehlerae (another common agent of ...
TheFetus.net website was created with the goal of sharing experiences in prenatal diagnosis to enrich the practitioners knowledge worldwide. Since the first case of the week was published in May 1999, we have become an international community that works together to improve healthcare across the globe. We appreciate support of any kind so we can continue to pursue this vision for many years to come. TheFetus.net is registered as a 501(c)3 non-profit organization with the United States Internal Revenue Service and your donations are tax deductible. TheFetus.net is generously supported by donations from the Thomas Nelson Abdella MD Foundation, which strives to support education in maternal fetal medicine. ...
  • citation needed] Possibly Bartonella spp bacteraemia[citation needed] Hemangioendotheliomas may be classified as: Epithelioid hemangioendothelioma is an uncommon vascular tumor of intermediate malignancy that was first described by Steven Billings, Andrew Folpe, and Sharon Weiss in 2003. (wikipedia.org)
  • Epithelioid Hemangioendothelioma is a rare form of cancer that affects the blood vessels of an individual and has an unknown etiology. (ipl.org)
  • Epithelioid Hemangioendothelioma affects about 0.1 percent of the American population with an overall 5-year survival rate of 55% after a standard primary radical treatment. (ipl.org)
  • Crazy sexy cancer is a documentary about a young lady, age 31, who was diagnosed with epithelioid Hemangioendothelioma, stage IV cancer on Valentine's day in 2003. (ipl.org)
  • It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (uchicago.edu)
  • Epithelioid Hemangioendothelioma: Update on Diagnosis and Treatment. (uchicago.edu)
  • Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma. (uchicago.edu)
  • Clinical patterns and outcome in epithelioid hemangioendothelioma with or without pulmonary involvement: insights from an internet registry in the study of a rare cancer. (uchicago.edu)
  • Mediastinal epithelioid hemangioendothelioma metastatic to lymph nodes and pleural fluid: report of a case. (uchicago.edu)
  • Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 cases. (uchicago.edu)
  • Left atrial epithelioid hemangioendothelioma. (uchicago.edu)
  • Foods for Epithelioid Hemangioendothelioma! (addon.life)
  • Introduction Foods for Epithelioid Hemangioendothelioma should be personalized for each individual and also must adapt when cancer treatment or tumor genetic change. (addon.life)
  • Epithelioid Hemangioendothelioma: A distinctive vascular tumor often mistaken for carcinoma. (neoplasiaresearch.com)
  • Malignant vascular tumors: Epithelioid Hemangioendothelioma. (neoplasiaresearch.com)
  • Epithelioid hemangioendothelioma (EHE) is a rare neoplasm originating from various organs. (elsevierpure.com)
  • Neuroimaging revealed a heterogeneously enhancing mass with invasion into the transverse sinus, diagnosed as an epithelioid hemangioendothelioma by surgical pathology. (iasp-pain.org)
  • The name of the cancer itself is frightening: epithelioid hemangioendothelioma - a type of vascular cancer inside the blood vessels. (cancure.org)
  • WWTR1 (TAZ)- CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis. (bvsalud.org)
  • 15: Puls F, Niblett A, Clarke J, Kindblom LG, McCulloch T. YAP1-TFE3 epithelioid hemangioendothelioma: a case without vasoformation and a new transcript variant. (cancercentrum.se)
  • 601 Kaposiform hemangioendothelioma (also known as "Infantile kaposiform hemangioendothelioma") is an uncommon vascular tumor, first described by Niedt, Greco, et al. (wikipedia.org)
  • Kaposiform hemangioendothelioma (KHE) is a rare and aggressive vascular tumor that is benign (noncancerous and does not spread to other locations in the body). (texaschildrens.org)
  • Mediastinal Kaposiform hemangioendothelioma and Kasabach-Merritt phenomenon in an infant: treatment with interferon. (qxmd.com)
  • A 2-week-old infant developed respiratory failure due to a mediastinal Kaposiform hemangioendothelioma that was complicated by thrombocytopenia and consumptive coagulopathy. (qxmd.com)
  • This case demonstrates that interferon can be used to treat infants with Kaposiform hemangioendothelioma in life-threatening situations that do not respond to other forms of treatment. (qxmd.com)
  • Some patients with diffuse cavernous kaposiform hemangioendothelioma (KHE) of a visceral organ may present with anemia, thrombocytopenia, coagulopathy, and bleeding, which may be misdiagnosed as immune thrombocytopenic purpura. (medscape.com)
  • Leg with a Kaposiform hemangioendothelioma, lesion associated with Kasabach-Merritt Syndrome. (medscape.com)
  • Lola was born with a large visible kaposiform hemangioendothelioma with kasbach merit. (birthmark.org)
  • An Unusual Presentation of Kaposiform Hemangioendothelioma in the Mandibular Bone. (ucsf.edu)
  • The lesion in this original case was a kaposiform hemangioendothelioma, not a classic infantile hemangioma. (medscape.com)
  • The combination of enlarging vascular lesion (either a kaposiform hemangioendothelioma or a tufted angioma), profound thrombocytopenia, microangiopathic hemolytic anemia, and consumption coagulopathy is termed KMS or Kasabach-Merritt phenomenon (KMP). (medscape.com)
  • Kaposiform hemangioendothelioma: five patients with cutaneous lesion and long follow-up. (wikigenes.org)
  • Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. (wikipedia.org)
  • title = Clinical features of infantile hepatic hemangioendothelioma. (librepathology.org)
  • title = Infantile hepatic hemangioendothelioma in comparison with hepatoblastoma in children: clinical and ultrasound features. (librepathology.org)
  • title = Infantile hepatic hemangioendothelioma: a clinicopathologic study in a Chinese population. (librepathology.org)
  • Return to Infantile hepatic hemangioendothelioma . (librepathology.org)
  • Hepatic hemangioendothelioma (inc. (childrensmercy.org)
  • 3,4 Studies show no clear evidence of genetic transmission 3 and no racial predominance in infantile hepatic hemangioendothelioma. (contemporarypediatrics.com)
  • 599 These tumors were reclassified by Dr. Weiss in 1996 as "spindle cell hemangioma", rather than hemangioendothelioma, due to the excellent prognosis observed in a group of 78 patients. (wikipedia.org)
  • In children, distinguishing between a primary malignant liver tumor (hepatoblastoma) and a benign primary hepatic lesion (hemangioendothelioma) is crucial. (wikipedia.org)
  • We present a challenging lymphocyte-rich soft tissue lesion that was not recognized to be an unusual hemangioendothelioma until after several recurrences in the arm of a 63 year-old male, which was originally diagnosed as a follicular dendritic cell tumor instead. (neoplasiaresearch.com)
  • Retiform hemangioendothelioma (also known as a "Hobnail hemangioendothelioma") is a low-grade angiosarcoma, first described in 1994, presenting as a slow-growing exophytic mass, dermal plaque, or subcutaneous nodule. (wikipedia.org)
  • Retiform hemangioendothelioma (RH) is a rare vascular neoplasm with a high rate of local recurrence and low metastatic potential. (johnshopkins.edu)
  • The absence of urinary catecholamines supports the diagnosis of hemangioendothelioma. (wikipedia.org)
  • The diagnosis was revised to recurrent lymphocyte-rich hemangioendothelioma. (neoplasiaresearch.com)
  • 601 Spindle-cell hemangioendothelioma) is a vascular tumor that was first described in 1986 by Sharon Weiss, M.D., and commonly presents in a child or young adult who develops blue nodules of firm consistency on a distal extremity. (wikipedia.org)
  • 596 : 1782 Endovascular papillary angioendothelioma, also known as "Dabska tumor", "papillary intralymphatic angioendothelioma" (PILA), "Dabska-type hemangioendothelioma", "hobnail hemangioendothelioma", and "malignant endovascular papillary angioendothelioma", is a rare low-grade angiosarcoma: 601 of lymphatic channels. (wikipedia.org)
  • Hemangioendothelioma is a vascular tumor with several different morphologic patterns that can include a component of ovoid or spindled cells, but generally lacks an inflammatory component. (neoplasiaresearch.com)
  • Infantile hemangioendothelioma is the third most common hepatic tumor in neonates and the most common benign liver tumor in this age-group. (contemporarypediatrics.com)
  • Infantile hemangioendothelioma is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the liver. (wikipedia.org)
  • title = Infantile hemangioendothelioma of the liver. (librepathology.org)
  • Infantile hemangioendothelioma of the liver:A case report and review l" by B. Chareonsil, J. Singhavechasakul et al. (chula.ac.th)
  • Composite hemangioendothelioma is a low-grade angiosarcoma typically occurring in adults, although it has been described in infancy. (wikipedia.org)
  • This represents an unusual and potentially confusing pattern of hemangioendothelioma that is not previously well described in the literature. (neoplasiaresearch.com)
  • This graph shows the total number of publications written about "Hemangioendothelioma, Epithelioid" by people in this website by year, and whether "Hemangioendothelioma, Epithelioid" was a major or minor topic of these publications. (uchicago.edu)
  • Infantile hemangioendothelioma is a rare benign vascular tumour arising from mesenchymal tissue and is usually located in the liver. (wikipedia.org)
  • Infantile hepatic hemangioendothelioma is strongly suggested by the presence of a vascular lesion on imaging studies. (wikipedia.org)
  • Treatment for infantile hemangioendothelioma depends on the child's growth and development. (medlineplus.gov)
  • METHODS: Six patients with advanced and pretreated but progressive, malignant vascular tumors (5 angiosarcomas and 1 hemangioendothelioma) received a combination of pioglitazone (45 mg per day orally) plus rofecoxib (25 mg per day orally) and, after 14 days, trofosfamide (3 x 50 mg per day orally). (uni-regensburg.de)
  • 4. Spindle cell hemangioendothelioma. (nih.gov)
  • 9. Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases. (nih.gov)
  • 1. Cutaneous composite hemangioendothelioma: case report and review of published reports. (nih.gov)
  • 2. Composite hemangioendothelioma arising from the kidney: case report with review of the literature. (nih.gov)
  • 3. Composite hemangioendothelioma: report of 5 cases including one with associated Maffucci syndrome. (nih.gov)
  • 5. Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma. (nih.gov)
  • 8. The First Case of Composite Hemangioendothelioma in The Heart. (nih.gov)
  • MAML2 fusions in composite hemangioendothelioma with neuroendocrine differentiation: A report of two cases involving neck lymph nodes. (nih.gov)
  • Thoracic composite hemangioendothelioma with neuroendocrine marker expression. (nih.gov)