Hemangioma
Hemangioma, Cavernous
Hemangioma, Capillary
Pulmonary Sclerosing Hemangioma
Hemangioma, Cavernous, Central Nervous System
Granuloma, Pyogenic
Hemangioendothelioma
Vascular Neoplasms
Facial Neoplasms
Spinal Neoplasms
Neoplasms, Vascular Tissue
Neoplasm Regression, Spontaneous
Hemangiosarcoma
Tomography, X-Ray Computed
Epidural Neoplasms
Angiolymphoid Hyperplasia with Eosinophilia
Pregnancy Complications, Neoplastic
Sturge-Weber Syndrome
Muscle Neoplasms
Magnetic Resonance Imaging
Angiomatosis
Frontal Bone
Avian Leukosis
Choroid Neoplasms
Hemangioendothelioma, Epithelioid
Eye Pain
Heart Neoplasms
Histiocytoma, Benign Fibrous
Laminectomy
Focal aneurysmal dilatation of subchorionic vessels simulating chorioangioma. (1/770)
Subchorionic vascular aneurysms of the placenta are rare lesions and may present confusion with chorioangioma or focal mesenchymal dysplasia on sonography. To our knowledge, the findings of placental aneurysms have not been reported in the ultrasound literature. We present a case with detailed sonographic evaluation, including spectral and color Doppler and pathological analysis, that was mistaken for chorioangioma prenatally. Knowledge of this benign entity may allow the sonologist to recommend conservative management in similar cases. (+info)Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice. (2/770)
Germ-line mutations of the human TSC2 tumor suppressor gene cause tuberous sclerosis (TSC), a disease characterized by the development of hamartomas in various organs. In the Eker rat, however, a germ-line Tsc2 mutation gives rise to renal cell carcinomas with a complete penetrance. The molecular mechanism for this phenotypic difference between man and rat is currently unknown, and the physiological function of the TSC2/Tsc2 product (tuberin) is not fully understood. To investigate these unsolved problems, we have generated a Tsc2 mutant mouse. Tsc2 heterozygous mutant (Tsc2+/-) mice developed renal carcinomas with a complete penetrance, as seen in the Eker rat, but not the angiomyolipomas characteristic of human TSC, confirming the existence of a species-specific mechanism of tumorigenesis caused by tuberin deficiency. Unexpectedly, approximately 80% of Tsc2+/- mice also developed hepatic hemangiomas that are not observed in either TSC or the Eker rat. Tsc2 homozygous (Tsc2-/-) mutants died around embryonic day 10.5, indicating an essential function for tuberin in mouse embryonic development. Some Tsc2-/- embryos exhibited an unclosed neural tube and/or thickened myocardium. The latter is associated with increased cell density that may be a reflection of loss of a growth-suppressive function of tuberin. The mouse strain described here should provide a valuable experimental model to analyze the function of tuberin and its association with tumorigenesis. (+info)Color Doppler sonography of focal lesions of the skin and subcutaneous tissue. (3/770)
We evaluated with color Doppler sonography 71 visible and palpable nodules of the skin and subcutaneous tissue from 51 patients. The nodules were classified as avascular (type I), hypovascular with a single vascular pole (type II), hypervascular with multiple peripheral poles (type III), and hypervascular with internal vessels (type IV). Of the 32 malignant nodules, 9% showed a type I pattern, 50% had a type III pattern, and 41% had a type IV pattern; of the 39 benign nodules, 86% showed a type I pattern and 14% had a type II pattern. The sensitivity and specificity of hypervascularity in malignant lesions were 90% and 100%, respectively, whereas the sensitivity and specificity of hypovascularity in benign lesions were 100% and 90%, respectively. The authors conclude that color Doppler sonography is able to increase the specificity of ultrasonography in the evaluation of nodular lesions of the skin. (+info)Third International Meeting on von Hippel-Lindau disease. (4/770)
Five years after the identification of the von Hippel-Lindau (VHL) gene, physicians, scientists and concerned VHL family members met to review the current state of knowledge on the diagnosis and treatment of VHL and to summarize the latest information on the biochemistry of the VHL protein (pVHL). The NIH and University of Pennsylvania groups reported the detection of germ-line mutations in 100% (93 of 93) of VHL families studied. Several studies determined the frequency of VHL germ-line mutations in individuals with a single manifestation of VHL without a family history of VHL. National groups to improve the diagnosis and treatment of individuals with VHL disease have been established in Great Britain, Denmark, France, Holland, Italy, Japan, Poland, and the United States. Evidence for the existence of genes that modify the expression of VHL was presented. The VHL protein appears to have several distinct functions: (a) down-regulation of hypoxia-inducible mRNAs; (b) proper assembly of the extracellular fibronectin matrix; (c) regulation of exit from the cell cycle; and (d) regulation of expression of carbonic anhydrases 9 and 12. (+info)Complications of angioma surgery--personal experience in 191 patients with cerebral angiomas. (5/770)
In the last years, treatment decisions of arteriovenous malformations (AVMs) were influenced by the improvement of stereotactic radiosurgery and were revolutionized by development of embolization techniques. The aim of this report was to examine the results, effectiveness, and complications associated with angioma surgery. 191 patients with AVMs were operated by the first author between 1981 and 1996. Angioma localization was distributed as follows: frontal 51 (26.7%), temporal 44 (23%), parietal 45 (23.6%), and occipital 24 (12.6%). Twelve (6.3%) AVMs were located in the cerebellum and 15 (7.9%) in other deep regions. Twenty-nine (15.2%) AVMs were associated with single or multiple aneurysms. The preoperative symptoms were hemorrhage (50.3%), seizure (33.5%), headache (23.0%), focal neurological deficits (12.6%), and other minor symptoms. In 9.9%, the disease remains preoperatively asymptomatic. Based on the Spetzler/Martin scale (S/M), 38 patients were grade I, 39 grade II, 52 grade III, 39 grade IV, and 23 grade V. The following severe complications were observed: postoperative hemorrhage in 13 (6.8%), infection in six (3.1%), infarction in two (1.0%), and death in three (1.6%). The risk for postoperative complications was related to the preoperative S/M grade of the AVM. Severe complications only occurred in AVM grades IV and V. In 62 patients with grade IV and V AVM, three patients died (4.8%) and 12 showed neurological deterioration (19.4%). Only 3/129 (2.3%) patients with grade I-III AVM deteriorated postoperatively. No severe complications were observed in preembolized and recently operated patients. Microsurgical management of cerebral AVMs seems to be a reasonably safe procedure especially in grade I-III AVMs, with a mortality of less than 2%. With enough experience and exact attention to detail, the experienced neurosurgeon can remove many of these AVMs with a minimum of risk to the affected patient. Although hemorrhage from an AVM can be disabling or deadly, the course in many nonoperated high-grade AVMs (S/M grades IV and V) can be quite benign, if compared with their surgical risk. This may justify conservative treatment or treatment with radiosurgery in some high-grade (S/M grades IV and V) angiomas, especially in elderly patients. (+info)A novel animal model for hemangiomas: inhibition of hemangioma development by the angiogenesis inhibitor TNP-470. (6/770)
Hemangiomas represent the most frequent tumors of infancy. However, the pathogenesis of these tumors is still largely unknown, and current treatment of juvenile hemangiomas remains unsatisfactory. Here we present a novel animal model to study proliferating hemangiomas and to evaluate the effect of angiostatic compounds on their growth. Intraperitoneal (i.p.) infection of 4-day-old rats with murine polyomavirus resulted in the development of multiple cutaneous, intramuscular (i.m.), and cerebral hemangiomas with 100% frequency. Histological examination of the brain revealed the formation of immature lesions as soon as 4 days postinfection (p.i.). The subsequent exponential growth of the hemangiomas, both in number and size, was associated with severe hemorrhage and anemia. The cerebral, cutaneous, and i.m. lesions consisted of blood-filled cysts, histologically similar to human cavernous hemangiomas and stained positive for proliferating cell nuclear antigen, urokinase-type plasminogen activator, and vascular endothelial growth factor. Mature cerebral hemangiomas also expressed von Willebrand factor. Cerebral lesions caused death of the untreated animals within 19.2 +/- 1.1 days p.i. Remarkably fewer and smaller hemangiomas developed in animals that had been treated s.c. with the angiogenesis inhibitor TNP-470. Accordingly, TNP-470 (50 mg/kg), administered twice a week from 3 days p.i., significantly delayed tumor-associated mortality [mean day of death, 28.2 +/- 3.3 (P < 0.001)]. Even if therapy was initiated when cerebral hemangiomas were already macroscopically visible (i.e., 9 days p.i.), a significant delay in hemangioma-associated mortality was observed. Also, the IFN-inducer polyinosinic-polycytidylic acid caused a delay of 9 days (P < 0.005) in tumor-associated mortality when administered i.p. at 5 mg/kg, twice a week, starting at day 3 p.i. The model described here may be useful for investigating (a) the angiogenic mechanism(s) underlying hemangioma progression; and (b) the effect of anti-angiogenic compounds on vascular tumor growth. (+info)In utero diagnosis of cardiac hemangioma. (7/770)
Fetal cardiac hemangioma is rarely diagnosed prenatally. We present here a fetus with such a tumor diagnosed at 28 weeks' gestation. With the use of fetal echocardiography, a mixed echogenic mass protruding outward from the right atrial wall was observed. Moderate amounts of pericardial effusion were also found. Although no apparent blood flow signal was detected in the mass, fetal echocardiography showed signs suggestive of a hemangioma. Differential diagnosis, management and prognosis are discussed. (+info)Clinical significance of intracranial developmental venous anomalies. (8/770)
OBJECTIVES: Venous angiomas, or developmental venous anomalies (DVAs), represent the most often occurring cerebral vascular malformation. The clinical significance of a DVA is, however, at present unclear. METHODS: A retrospective analysis was carried out on two series of consecutive cranial MRIs performed between January 1990 and August 1996 in a university department of neuroradiology and in a large radiological private practice. The medical records of all patients in whom a DVA was diagnosed were screened to identify the specific complaint which necessitated the imaging procedure. RESULTS: A total of 67 patients with DVA could be identified. In 12 patients an associated cavernoma was found. The main reason for performing the MRI was the evaluation of seizures or of headaches. In all patients with DVA in whom an intracerebral haemorrhage was diagnosed an associated cavernoma was present at the site of the haemorrhage. None of the 67 patients showed an association between the complaints that led to the MRI and the location of the DVA. CONCLUSIONS: DVAs do not seem to be associated with a specific clinical presentation. In a significant percentage of cases, however, coexisting cavernomas are found which have a defined bleeding potential and should be treated independently of the DVA. This study supports the hypothesis that DVAs are a congenital abnormality of venous drainage without clinical significance. (+info)A hemangioma is a benign (noncancerous) vascular tumor or growth that originates from blood vessels. It is characterized by an overgrowth of endothelial cells, which line the interior surface of blood vessels. Hemangiomas can occur in various parts of the body, but they are most commonly found on the skin and mucous membranes.
Hemangiomas can be classified into two main types:
1. Capillary hemangioma (also known as strawberry hemangioma): This type is more common and typically appears during the first few weeks of life. It grows rapidly for several months before gradually involuting (or shrinking) on its own, usually within the first 5 years of life. Capillary hemangiomas can be superficial, appearing as a bright red, raised lesion on the skin, or deep, forming a bluish, compressible mass beneath the skin.
2. Cavernous hemangioma: This type is less common and typically appears during infancy or early childhood. It consists of large, dilated blood vessels and can occur in various organs, including the skin, liver, brain, and gastrointestinal tract. Cavernous hemangiomas on the skin appear as a rubbery, bluish mass that does not typically involute like capillary hemangiomas.
Most hemangiomas do not require treatment, especially if they are small and not causing any significant problems. However, in cases where hemangiomas interfere with vital functions, impair vision or hearing, or become infected, various treatments may be considered, such as medication (e.g., corticosteroids, propranolol), laser therapy, surgical excision, or embolization.
A cavernous hemangioma is a type of benign vascular tumor that is made up of large, dilated blood vessels. It is characterized by the presence of large, "cavernous" spaces or sacs filled with blood. These lesions can occur in various parts of the body, but when they occur in the skin or mucous membranes, they appear as well-circumscribed rubbery masses that are compressible and blanchable (turn pale when pressed).
Cavernous hemangiomas are most commonly found on the face and neck, but they can also occur in other parts of the body such as the liver. They typically grow slowly during infancy or early childhood and then stabilize or even regress spontaneously over time. However, if they are located in critical areas such as the airway or near vital organs, they may require treatment to prevent complications.
Histologically, cavernous hemangiomas are composed of large, irregularly shaped vascular spaces lined by a single layer of endothelial cells and surrounded by fibrous tissue. Treatment options for cavernous hemangiomas include observation, compression therapy, laser therapy, surgical excision, or embolization.
A capillary hemangioma is a benign (non-cancerous) vascular tumor that is made up of an overgrowth of small blood vessels called capillaries. These lesions are quite common and usually appear during the first few weeks or months of life, although they can also develop later in childhood or even in adulthood.
Capillary hemangiomas typically appear as a bright red, raised, and rubbery lesion on the skin. They may be small and localized, or they can grow and spread to cover a larger area of the body. In some cases, capillary hemangiomas may also form on internal organs such as the liver, brain, or gastrointestinal tract.
While capillary hemangiomas are generally harmless, they can cause cosmetic concerns if they appear on the face or other visible areas of the body. In some cases, these lesions may also interfere with vision, hearing, or other bodily functions if they grow too large or are located in sensitive areas.
Most capillary hemangiomas will eventually shrink and disappear on their own over time, typically within the first few years of life. However, in some cases, medical treatment may be necessary to help speed up this process or to address any complications that arise. Treatment options for capillary hemangiomas may include medications such as corticosteroids or beta-blockers, laser therapy, or surgical removal.
Pulmonary sclerosing hemangioma is a rare, benign lung tumor of uncertain origin. It is also known as sclerosing pneumocytoma. This tumor primarily affects adults, with women being more commonly affected than men. The typical symptoms include cough, chest pain, and sometimes blood-streaked sputum. However, many cases are asymptomatic and discovered incidentally on chest imaging.
On histopathology, pulmonary sclerosing hemangioma is characterized by the presence of two types of cells: surface cells (similar to type II pneumocytes) and round cells (similar to mesenchymal cells). The tumor shows a variety of architectural patterns including solid areas, papillary structures, and hemorrhagic cavities.
The treatment of choice is surgical resection. Despite its benign nature, there have been reports of recurrence after incomplete resection. However, the prognosis after complete resection is excellent.
A cavernous hemangioma in the central nervous system (CNS) refers to a type of benign vascular tumor that is made up of dilated and thin-walled blood vessels. These tumors are called "cavernous" because they are filled with blood-filled sacs or "caverns."
When these hemangiomas occur in the CNS, which includes the brain and spinal cord, they can cause various neurological symptoms depending on their size and location. Small hemangiomas may not cause any symptoms at all, while larger ones can cause seizures, headaches, weakness, or sensory changes.
Cavernous hemangiomas in the CNS are typically congenital, meaning that they are present at birth. However, they may not become symptomatic until later in life. Treatment options for cavernous hemangiomas in the CNS include observation, surgery, or radiation therapy, depending on the size, location, and symptoms caused by the tumor.
A pyogenic granuloma is not precisely a "granuloma" in the strict medical definition, which refers to a specific type of tissue reaction characterized by chronic inflammation and the formation of granulation tissue. Instead, a pyogenic granuloma is a benign vascular tumor that occurs most frequently on the skin or mucous membranes.
Pyogenic granulomas are typically characterized by their rapid growth, bright red to dark red color, and friable texture. They can bleed easily, especially when traumatized. Histologically, they consist of a mass of small blood vessels, surrounded by loose connective tissue and inflammatory cells.
The term "pyogenic" is somewhat misleading because these lesions are not actually associated with pus or infection, although they can become secondarily infected. The name may have originated from the initial mistaken belief that these lesions were caused by a bacterial infection.
Pyogenic granulomas can occur at any age but are most common in children and young adults. They can be caused by minor trauma, hormonal changes, or underlying medical conditions such as pregnancy or vasculitis. Treatment typically involves surgical excision, although other options such as laser surgery or cauterization may also be used.
Hemangioendothelioma is a rare type of vascular tumor, which means it arises from the endothelial cells that line the blood vessels. It can occur in various parts of the body, but it most commonly involves the soft tissues and bones. Hemangioendotheliomas are often classified as borderline malignant tumors because they can behave either indolently (like a benign tumor) or aggressively (like a malignant tumor), depending on their specific type and location.
There are several subtypes of hemangioendothelioma, including:
1. Epithelioid hemangioendothelioma: This subtype typically affects young adults and can involve various organs, such as the liver, lungs, or soft tissues. It tends to have a more indolent course but can metastasize in some cases.
2. Kaposiform hemangioendothelioma: This is an aggressive subtype that usually occurs in infants and children. It often involves the skin and soft tissues, causing local invasion and consumptive coagulopathy (Kasabach-Merritt phenomenon).
3. Retiform hemangioendothelioma: A rare and low-grade malignant tumor that typically affects the skin and subcutaneous tissue of adults. It has a favorable prognosis with a low risk of metastasis.
4. Papillary intralymphatic angioendothelioma (PILA): This is a rare, slow-growing tumor that usually occurs in the head and neck region of children and young adults. It has an excellent prognosis with no reported cases of metastasis or recurrence after complete surgical resection.
Treatment for hemangioendotheliomas typically involves surgical excision when possible. Other treatment options, such as radiation therapy, chemotherapy, or targeted therapies, may be considered depending on the tumor's location, size, and behavior. Regular follow-up is essential to monitor for potential recurrence or metastasis.
Vascular neoplasms are a type of tumor that develops from cells that line the blood vessels or lymphatic vessels. These tumors can be benign (non-cancerous) or malignant (cancerous). Benign vascular neoplasms, such as hemangiomas and lymphangiomas, are usually harmless and may not require treatment unless they cause symptoms or complications. Malignant vascular neoplasms, on the other hand, are known as angiosarcomas and can be aggressive, spreading to other parts of the body and potentially causing serious health problems.
Angiosarcomas can develop in any part of the body but are most commonly found in the skin, particularly in areas exposed to radiation or chronic lymph edema. They can also occur in the breast, liver, spleen, and heart. Treatment for vascular neoplasms depends on the type, location, size, and stage of the tumor, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Skull neoplasms refer to abnormal growths or tumors that develop within the skull. These growths can be benign (non-cancerous) or malignant (cancerous). They can originate from various types of cells, such as bone cells, nerve cells, or soft tissues. Skull neoplasms can cause various symptoms depending on their size and location, including headaches, seizures, vision problems, hearing loss, and neurological deficits. Treatment options include surgery, radiation therapy, and chemotherapy. It is important to note that a neoplasm in the skull can also refer to metastatic cancer, which has spread from another part of the body to the skull.
Facial neoplasms refer to abnormal growths or tumors that develop in the tissues of the face. These growths can be benign (non-cancerous) or malignant (cancerous). Facial neoplasms can occur in any of the facial structures, including the skin, muscles, bones, nerves, and glands.
Benign facial neoplasms are typically slow-growing and do not spread to other parts of the body. Examples include papillomas, hemangiomas, and neurofibromas. While these tumors are usually harmless, they can cause cosmetic concerns or interfere with normal facial function.
Malignant facial neoplasms, on the other hand, can be aggressive and invasive. They can spread to other parts of the face, as well as to distant sites in the body. Common types of malignant facial neoplasms include basal cell carcinoma, squamous cell carcinoma, and melanoma.
Treatment for facial neoplasms depends on several factors, including the type, size, location, and stage of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. It is important to seek medical attention promptly if you notice any unusual growths or changes in the skin or tissues of your face.
Spinal neoplasms refer to abnormal growths or tumors found within the spinal column, which can be benign (non-cancerous) or malignant (cancerous). These tumors can originate in the spine itself, called primary spinal neoplasms, or they can spread to the spine from other parts of the body, known as secondary or metastatic spinal neoplasms. Spinal neoplasms can cause various symptoms, such as back pain, neurological deficits, and even paralysis, depending on their location and size. Early diagnosis and treatment are crucial to prevent or minimize long-term complications and improve the patient's prognosis.
A neoplasm of vascular tissue is an abnormal growth or mass of cells in the blood vessels or lymphatic vessels. These growths can be benign (non-cancerous) or malignant (cancerous). Benign neoplasms, such as hemangiomas and lymphangiomas, are typically not harmful and may not require treatment. However, they can cause symptoms if they grow large enough to press on nearby organs or tissues. Malignant neoplasms, such as angiosarcomas, are cancerous and can invade and destroy surrounding tissue, as well as spread (metastasize) to other parts of the body. Treatment for vascular tissue neoplasms depends on the type, size, location, and stage of the growth, and may include surgery, radiation therapy, chemotherapy, or a combination of these.
Spontaneous neoplasm regression is a rare and somewhat controversial phenomenon in which a tumor or malignancy appears to decrease in size or disappear without any treatment or with treatment that is typically not expected to produce such an effect. This can occur through various mechanisms, including immune-mediated processes, apoptosis (programmed cell death), differentiation of cancer cells into normal cells, and angiogenesis inhibition (preventing the growth of new blood vessels that feed the tumor).
Spontaneous regression of neoplasms is not well understood and is considered unpredictable. It has been reported in various types of cancers, including neuroblastoma, melanoma, renal cell carcinoma, and others. However, it should be noted that spontaneous regression does not imply a cure, as the tumor may still recur or metastasize later on.
In summary, spontaneous neoplasm regression refers to the partial or complete disappearance of a malignancy without any specific treatment or with treatment that is not typically associated with such an effect.
Hemangiosarcoma is a type of cancer that arises from the cells that line the blood vessels (endothelial cells). It most commonly affects middle-aged to older dogs, but it can also occur in cats and other animals, as well as rarely in humans.
This cancer can develop in various parts of the body, including the skin, heart, spleen, liver, and lungs. Hemangiosarcomas of the skin tend to be more benign and have a better prognosis than those that arise internally.
Hemangiosarcomas are highly invasive and often metastasize (spread) to other organs, making them difficult to treat. The exact cause of hemangiosarcoma is not known, but exposure to certain chemicals, radiation, and viruses may increase the risk of developing this cancer. Treatment options typically include surgery, chemotherapy, and/or radiation therapy, depending on the location and stage of the tumor.
X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.
The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.
CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.
In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.
CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.
In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.
Epidural neoplasms refer to abnormal growths or tumors that develop in the epidural space, which is the area between the dura mater (the outermost protective covering of the spinal cord) and the vertebral column. These tumors can be either primary, originating directly from the cells in the epidural space, or secondary, resulting from the spread (metastasis) of cancerous cells from other parts of the body.
Epidural neoplasms can cause various symptoms due to the compression of the spinal cord and nerve roots. These symptoms may include localized back pain, radiating pain, sensory changes, motor weakness, and autonomic dysfunction. The diagnosis typically involves imaging studies such as MRI or CT scans, followed by a biopsy for histopathological examination to confirm the type and grade of the tumor. Treatment options depend on several factors, including the patient's overall health, the location and size of the tumor, and the type and extent of neurological deficits. Treatment may involve surgical resection, radiation therapy, chemotherapy, or a combination of these approaches.
Liver neoplasms refer to abnormal growths in the liver that can be benign or malignant. Benign liver neoplasms are non-cancerous tumors that do not spread to other parts of the body, while malignant liver neoplasms are cancerous tumors that can invade and destroy surrounding tissue and spread to other organs.
Liver neoplasms can be primary, meaning they originate in the liver, or secondary, meaning they have metastasized (spread) to the liver from another part of the body. Primary liver neoplasms can be further classified into different types based on their cell of origin and behavior, including hepatocellular carcinoma, cholangiocarcinoma, and hepatic hemangioma.
The diagnosis of liver neoplasms typically involves a combination of imaging studies, such as ultrasound, CT scan, or MRI, and biopsy to confirm the type and stage of the tumor. Treatment options depend on the type and extent of the neoplasm and may include surgery, radiation therapy, chemotherapy, or liver transplantation.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vascular lesion that typically presents as one or multiple papules or nodules, often on the head and neck region. The exact cause of ALHE is unknown, but it has been associated with chronic inflammation and immune dysfunction.
Histologically, ALHE is characterized by the proliferation of blood vessels and lymphoid tissue, with a prominent infiltration of eosinophils. The lesions may also contain other inflammatory cells such as plasma cells, histiocytes, and T-lymphocytes.
Clinically, ALHE presents as red to brownish papules or nodules that can be tender or pruritic (itchy). Lesions typically occur on the head and neck region, particularly around the ears, eyes, and nose. In some cases, lesions may also appear on the trunk, arms, or legs.
While ALHE is a benign condition, it can cause significant cosmetic concerns due to its location. Treatment options include surgical excision, laser therapy, and intralesional corticosteroid injections. Recurrence after treatment is not uncommon. It is important to note that while ALHE may resemble other more serious conditions such as cutaneous lymphoma or angiosarcoma, it has a much more favorable prognosis.
Orbital neoplasms refer to abnormal growths or tumors that develop in the orbit, which is the bony cavity that contains the eyeball, muscles, nerves, fat, and blood vessels. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells within the orbit.
Orbital neoplasms can cause a variety of symptoms depending on their size, location, and rate of growth. Common symptoms include protrusion or displacement of the eyeball, double vision, limited eye movement, pain, swelling, and numbness in the face. In some cases, orbital neoplasms may not cause any noticeable symptoms, especially if they are small and slow-growing.
There are many different types of orbital neoplasms, including:
1. Optic nerve glioma: a rare tumor that arises from the optic nerve's supportive tissue.
2. Orbital meningioma: a tumor that originates from the membranes covering the brain and extends into the orbit.
3. Lacrimal gland tumors: benign or malignant growths that develop in the lacrimal gland, which produces tears.
4. Orbital lymphangioma: a non-cancerous tumor that arises from the lymphatic vessels in the orbit.
5. Rhabdomyosarcoma: a malignant tumor that develops from the skeletal muscle cells in the orbit.
6. Metastatic tumors: cancerous growths that spread to the orbit from other parts of the body, such as the breast, lung, or prostate.
The diagnosis and treatment of orbital neoplasms depend on several factors, including the type, size, location, and extent of the tumor. Imaging tests, such as CT scans and MRI, are often used to visualize the tumor and determine its extent. A biopsy may also be performed to confirm the diagnosis and determine the tumor's type and grade. Treatment options include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Neoplastic pregnancy complications refer to the abnormal growth of cells (neoplasia) that can occur during pregnancy. These growths can be benign or malignant and can arise from any type of tissue in the body. However, when they occur in pregnant women, they can pose unique challenges due to the potential effects on the developing fetus and the changes in the mother's body.
Some common neoplastic pregnancy complications include:
1. Gestational trophoblastic disease (GTD): This is a group of rare tumors that occur in the uterus during pregnancy. GTD can range from benign conditions like hydatidiform mole to malignant forms like choriocarcinoma.
2. Breast cancer: Pregnancy-associated breast cancer (PABC) is a type of breast cancer that occurs during pregnancy or within one year after delivery. It can be aggressive and challenging to diagnose due to the changes in the breast tissue during pregnancy.
3. Cervical cancer: Cervical cancer can occur during pregnancy, and its management depends on the stage of the disease and the gestational age. In some cases, treatment may need to be delayed until after delivery.
4. Lung cancer: Pregnancy does not increase the risk of lung cancer, but it can make diagnosis and treatment more challenging.
5. Melanoma: Melanoma is the most common malignant skin cancer during pregnancy. It can spread quickly and requires prompt treatment.
The management of neoplastic pregnancy complications depends on several factors, including the type and stage of the tumor, gestational age, and the patient's wishes. In some cases, surgery, chemotherapy, or radiation therapy may be necessary. However, these treatments can have potential risks to the developing fetus, so a multidisciplinary team of healthcare providers is often involved in the care of pregnant women with neoplastic complications.
Sturge-Weber syndrome is a rare neurocutaneous disorder characterized by the combination of a facial port-wine birthmark and neurological abnormalities. The facial birthmark, which is typically located on one side of the face, occurs due to the malformation of small blood vessels (capillaries) in the skin and eye.
Neurological features often include seizures that begin in infancy, muscle weakness or paralysis on one side of the body (hemiparesis), developmental delay, and intellectual disability. These neurological symptoms are caused by abnormal blood vessel formation in the brain (leptomeningeal angiomatosis) leading to increased pressure, reduced blood flow, and potential damage to the brain tissue.
Sturge-Weber syndrome can also affect the eyes, with glaucoma being a common occurrence due to increased pressure within the eye. Early diagnosis and appropriate management of this condition are crucial for improving the quality of life and reducing potential complications.
Muscle neoplasms are abnormal growths or tumors that develop in the muscle tissue. They can be benign (non-cancerous) or malignant (cancerous). Benign muscle neoplasms are typically slow-growing and do not spread to other parts of the body, while malignant muscle neoplasms, also known as soft tissue sarcomas, can grow quickly, invade nearby tissues, and metastasize (spread) to distant parts of the body.
Soft tissue sarcomas can arise from any of the muscles in the body, including the skeletal muscles (voluntary muscles that attach to bones and help with movement), smooth muscles (involuntary muscles found in the walls of blood vessels, digestive tract, and other organs), or cardiac muscle (the specialized muscle found in the heart).
There are many different types of soft tissue sarcomas, each with its own set of characteristics and prognosis. Treatment for muscle neoplasms typically involves a combination of surgery, radiation therapy, and chemotherapy, depending on the type, size, location, and stage of the tumor.
Medical Definition:
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.
Angiomatosis is a medical term that refers to a benign condition characterized by the proliferation of blood vessels in various tissues and organs. It is typically composed of small, tangled blood vessels called capillaries, which can form clusters or networks. The condition can affect skin, internal organs, bones, and other tissues.
Angiomatosis is often asymptomatic and may be discovered incidentally during medical imaging or surgical procedures. In some cases, it may cause symptoms such as pain, swelling, or bleeding, depending on the location and extent of the lesions.
While angiomatosis is generally a benign condition, in rare cases, it can be associated with malignant tumors or other medical conditions. Treatment options for angiomatosis depend on the size, location, and symptoms of the lesions and may include observation, medication, or surgical removal.
Splenic neoplasms refer to abnormal growths or tumors in the spleen, which can be benign (non-cancerous) or malignant (cancerous). These growths can arise from various cell types present within the spleen, including hematopoietic cells (red and white blood cells, platelets), stromal cells (supporting tissue), or lymphoid cells (part of the immune system).
There are several types of splenic neoplasms:
1. Hematologic malignancies: These are cancers that affect the blood and bone marrow, such as leukemias, lymphomas, and multiple myeloma. They often involve the spleen, causing enlargement (splenomegaly) and neoplastic infiltration of splenic tissue.
2. Primary splenic tumors: These are rare and include benign lesions like hemangiomas, lymphangiomas, and hamartomas, as well as malignant tumors such as angiosarcoma, littoral cell angiosarcoma, and primary splenic lymphoma.
3. Metastatic splenic tumors: These occur when cancer cells from other primary sites spread (metastasize) to the spleen. Common sources of metastasis include lung, breast, colon, and ovarian cancers, as well as melanomas and sarcomas.
Symptoms of splenic neoplasms may vary depending on the type and extent of the disease but often include abdominal pain or discomfort, fatigue, weight loss, and anemia. Diagnosis typically involves imaging studies (such as ultrasound, CT, or MRI scans) and sometimes requires a biopsy for confirmation. Treatment options depend on the type of neoplasm and may include surgery, chemotherapy, radiation therapy, targeted therapy, or immunotherapy.
The frontal bone is the bone that forms the forehead and the upper part of the eye sockets (orbits) in the skull. It is a single, flat bone that has a prominent ridge in the middle called the superior sagittal sinus, which contains venous blood. The frontal bone articulates with several other bones, including the parietal bones at the sides and back, the nasal bones in the center of the face, and the zygomatic (cheek) bones at the lower sides of the orbits.
Avian leukosis is a group of viral diseases that primarily affect chickens and other birds. It is caused by retroviruses known as avian leukosis viruses (ALVs) and leads to a variety of clinical signs, including immunosuppression, growth retardation, and the development of tumors in various organs. The disease can be transmitted both horizontally (through direct contact with infected birds or their secretions) and vertically (from infected hens to their offspring through the egg).
There are several subgroups of ALVs, each associated with specific types of tumors and clinical manifestations. For example:
1. ALV-J (Japanese strain): This subgroup is responsible for myelocytomatosis, a condition characterized by the proliferation of immature blood cells in the bone marrow, leading to anemia, leukopenia, and enlarged spleens and livers.
2. ALV-A, ALV-B, and ALV-C (American strains): These subgroups are associated with various types of lymphoid tumors, such as B-cell and T-cell lymphomas, which can affect the bursa of Fabricius, thymus, spleen, and other organs.
3. ALV-E (European strain): This subgroup is linked to erythroblastosis, a condition in which there is an excessive proliferation of red blood cell precursors, resulting in the formation of tumors in the bone marrow and other organs.
Avian leukosis poses significant economic challenges for the poultry industry due to its impact on growth, feed conversion efficiency, and mortality rates. Additionally, some countries have regulations in place to prevent the spread of avian leukosis viruses through the trade of infected birds or their products. Prevention measures include strict biosecurity protocols, vaccination programs, and rigorous screening and eradication strategies for infected flocks.
Choroid neoplasms are abnormal growths that develop in the choroid, a layer of blood vessels that lies between the retina and the sclera (the white of the eye). These growths can be benign or malignant (cancerous). Benign choroid neoplasms include choroidal hemangiomas and choroidal osteomas. Malignant choroid neoplasms are typically choroidal melanomas, which are the most common primary eye tumors in adults. Other types of malignant choroid neoplasms include metastatic tumors that have spread to the eye from other parts of the body. Symptoms of choroid neoplasms can vary depending on the size and location of the growth, but may include blurred vision, floaters, or a dark spot in the visual field. Treatment options depend on the type, size, and location of the tumor, as well as the patient's overall health and personal preferences.
Epithelioid Hemangioendothelioma is a rare type of vascular tumor that can develop in various parts of the body, such as the liver, lungs, bones, and soft tissues. It is characterized by the abnormal growth of endothelial cells, which line the interior surface of blood vessels.
Epithelioid Hemangioendothelioma is classified as a borderline malignant tumor, meaning it has the potential to behave in a benign or malignant manner. The tumor typically grows slowly and may remain localized for an extended period, but it can also metastasize (spread) to other parts of the body.
The epithelioid variant of Hemangioendothelioma is named for its distinctive appearance under a microscope. The tumor cells are large and have an epithelial-like morphology, which means they resemble the cells that make up the outer layer of the skin and other organs.
Clinical presentation and management of Epithelioid Hemangioendothelioma depend on the location and extent of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches. Regular follow-up is essential to monitor for any signs of recurrence or progression.
Eye pain is defined as discomfort or unpleasant sensations in the eye. It can be sharp, throbbing, stabbing, burning, or aching. The pain may occur in one or both eyes and can range from mild to severe. Eye pain can result from various causes, including infection, inflammation, injury, or irritation of the structures of the eye, such as the cornea, conjunctiva, sclera, or uvea. Other possible causes include migraines, optic neuritis, and glaucoma. It is essential to seek medical attention if experiencing sudden, severe, or persistent eye pain, as it can be a sign of a serious underlying condition that requires prompt treatment.
Heart neoplasms are abnormal growths or tumors that develop within the heart tissue. They can be benign (noncancerous) or malignant (cancerous). Benign tumors, such as myxomas and rhabdomyomas, are typically slower growing and less likely to spread, but they can still cause serious complications if they obstruct blood flow or damage heart valves. Malignant tumors, such as angiosarcomas and rhabdomyosarcomas, are fast-growing and have a higher risk of spreading to other parts of the body. Symptoms of heart neoplasms can include shortness of breath, chest pain, fatigue, and irregular heart rhythms. Treatment options depend on the type, size, and location of the tumor, and may include surgery, radiation therapy, or chemotherapy.
Melena is a medical term that refers to the passage of black, tarry stools. It's not a specific disease but rather a symptom caused by the presence of digested blood in the gastrointestinal tract. The dark color results from the breakdown of hemoglobin, the protein in red blood cells, by gut bacteria and stomach acids.
Melena stools are often associated with upper gastrointestinal bleeding, which can occur due to various reasons such as gastric ulcers, esophageal varices (dilated veins in the esophagus), Mallory-Weiss tears (tears in the lining of the esophagus or stomach), or tumors.
It is essential to differentiate melena from hematochezia, which refers to the passage of bright red blood in the stool, typically indicating lower gastrointestinal bleeding. A healthcare professional should evaluate any concerns related to changes in bowel movements, including the presence of melena or hematochezia.
Benign fibrous histiocytoma (BFH) is a common benign tumor of the skin and superficial soft tissues. It primarily affects middle-aged adults and is more prevalent in men than women. The exact cause of BFH is unknown, but it's thought to arise from dermal fibroblasts or histiocytes.
Medical Definition: Benign Fibrous Histiocytoma (BFH) is a benign, slowly growing, solitary cutaneous or subcutaneous nodular tumor predominantly composed of a mixture of fibroblastic and histiocytic-like cells. The tumor typically presents as a well-circumscribed, firm, dome-shaped papule or nodule, ranging in size from a few millimeters to several centimeters. Histologically, BFH is characterized by the proliferation of spindle-shaped fibroblasts and histiocytes arranged in a storiform pattern, along with variable amounts of collagen deposition, multinucleated giant cells, and hemosiderin deposits. The lesion usually has a pushing border with no invasion into the surrounding tissues. BFH generally follows a benign clinical course, with local recurrence being uncommon following complete surgical excision.
A laminectomy is a surgical procedure that involves the removal of the lamina, which is the back part of the vertebra that covers the spinal canal. This procedure is often performed to relieve pressure on the spinal cord or nerves caused by conditions such as herniated discs, spinal stenosis, or tumors. By removing the lamina, the surgeon can access the affected area and alleviate the compression on the spinal cord or nerves, thereby reducing pain, numbness, or weakness in the back, legs, or arms.
Laminectomy may be performed as a standalone procedure or in combination with other surgical techniques such as discectomy, foraminotomy, or spinal fusion. The specific approach and extent of the surgery will depend on the patient's individual condition and symptoms.
The thoracic vertebrae are the 12 vertebrae in the thoracic region of the spine, which is the portion between the cervical and lumbar regions. These vertebrae are numbered T1 to T12, with T1 being closest to the skull and T12 connecting to the lumbar region.
The main function of the thoracic vertebrae is to provide stability and support for the chest region, including protection for the vital organs within, such as the heart and lungs. Each thoracic vertebra has costal facets on its sides, which articulate with the heads of the ribs, forming the costovertebral joints. This connection between the spine and the ribcage allows for a range of movements while maintaining stability.
The thoracic vertebrae have a unique structure compared to other regions of the spine. They are characterized by having long, narrow bodies, small bony processes, and prominent spinous processes that point downwards. This particular shape and orientation of the thoracic vertebrae contribute to their role in limiting excessive spinal movement and providing overall trunk stability.
Hemangioma
Vertebral hemangioma
Microvenular hemangioma
Infantile hemangioma
Cavernous hemangioma
Sinusoidal hemangioma
Glomeruloid hemangioma
Targetoid hemosiderotic hemangioma
Cavernous liver hemangioma
Central nervous system cavernous hemangioma
Phakomatosis
Liver tumor
List of OMIM disorder codes
Cherry angioma
N. K. Venkataramana
Vascular tumor
Eye neoplasm
Venous translucence
Chorioangioma
PHACE syndrome
Averill A. Liebow
Macrodystrophia lipomatosa
Kasabach-Merritt syndrome
Triiodothyronine
Papillary renal cell carcinoma
Diffuse neonatal hemangiomatosis
Juvenile xanthogranuloma
Wladimir Wertelecki
Homeobox
Amaurosis fugax
Hemangioma - Wikipedia
Hemangioma Hope Newsletter
Hemangioma: MedlinePlus Medical Encyclopedia
Study Spotlights Features of Infantile Hemangioma Subset
Capillary Hemangioma: Background, Pathophysiology, Epidemiology
Had Surgery-Cavernous Hemangioma R Frontal and Temporal Lobes - Neurology - MedHelp
Orbital hemangioma » New York Eye Cancer Center
Liver Haemangioma - ABC Homeopathy
Orphanet: Partially involuting congenital hemangioma
Hemangioma: Disease Bioinformatics: Novus Biologicals
Pathology Outlines - Hemangioma
Hemangioma and Vascular Malformation Program | Contact Us | Boston Children's Hospital
Propanolol Oral Solution (Hemangeol): A Breakthrough in Treating Infantile Hemangioma
Cherry hemangioma
Hemangioma | Belgium| PDF | PPT| Case Reports | Symptoms | Treatment
Splenic hemangioma | Radiology Case | Radiopaedia.org
Quick Facts: Hemangiomas - Merck Manuals Consumer Version
Oral Hemangiomas: Practice Essentials, Pathophysiology, Etiology
Giant cavernous hemangioma of the liver with satellite nodules: Aspects on tumour/tissue interface: A case report
Role of trucut biopsy in diagnosis of hepatic haemangioma
Laser Treatment for Hemangioma - Laser NY
Keywords histology + hemangioma | PEIR Digital Library
Use of propranolol in infantile haemangioma among Chinese children | HKMJ
Origin of endothelial cells in infantile hemangiomas
Treating Hemangiomas: When to treat, when not to treat - Vascular Birthmarks Foundation
Dr. Linda's VBF Fact of the Week: Infantile Hemangiomas - Vascular Birthmarks Foundation
capillary hemangiomas
F-18 FDG PET/CT imaging of a parapharyngeal hemangioma.
Exploring the association between chorangioma and infantile haemangioma in singleton and multiple pregnancies: a case-control...
Capillary hemangiomas6
- Capillary hemangiomas are one of the most common benign orbital tumors of infancy. (medscape.com)
- Capillary hemangiomas are believed to be hamartomatous proliferations of vascular endothelial cells. (medscape.com)
- Periorbital capillary hemangiomas follow a similar course to hemangiomas on other parts of the body. (medscape.com)
- As many as 50% of systemic capillary hemangiomas can occur in the head and neck region. (medscape.com)
- Of all the patients who eventually develop capillary hemangiomas, 30% of them have evidence of their presence at birth, whereas 100% have manifest them by age 6 months. (medscape.com)
- Capillary hemangiomas are present in approximately 1-2% of neonates. (medscape.com)
Blood vessels16
- A hemangioma is an abnormal buildup of blood vessels in the skin or internal organs. (medlineplus.gov)
- Infantile hemangiomas are benign tumors characterized by an overgrowth of blood vessels. (pharmacytimes.com)
- Hemangeol's active ingredient, propranolol, is a non-selective beta-blocker that works by reducing the proliferation of blood vessels in the hemangioma. (pharmacytimes.com)
- No one knows what causes a clump of blood vessels to form a hemangioma. (merckmanuals.com)
- A hemangioma, also called a strawberry nevus, is an abnormal buildup of blood vessels from an unknown cause. (intelligentdental.com)
- A hemangioma is a type of vascular anomaly in which an abnormally large amount of small blood vessels group together to form a large clump on the skin. (michelegreenmd.com)
- An infantile hemangioma is a kind of vascular tumor made up of blood vessels, commonly called a "strawberry birthmark. (norcal-dermatology.com)
- Hemangiomas are a type of tumor of the blood vessels or the skin. (vin.com)
- A hemangioma or vascular nevus is a congenital new growth and hypertrophy of the blood vessels of the skin. (bookdome.com)
- Surgically, complete excision of the hemangioma and hemostasis of associated blood vessels is recommended with complete pathology and histology work-up of the mass. (oatext.com)
- Hemangiomas are simply a collection of extra blood vessels in the skin. (findmeacure.com)
- A hemangioma is a benign self involuting tumour of endothelial cells (the cells that line blood vessels) Haemangiomas of infancy They are connected to the circulatory system and filled with blood. (findmeacure.com)
- Before considering the hemangioma it is important to understand that there have been recent changes in the terminology used to define vascular anomalies (abnormal lumps made up of blood vessels). (findmeacure.com)
- 1.Strawberry Hemangioma is an abnormal collection of blood vessels in the skin characterized by a bright red color and well-defined border. (findmeacure.com)
- 2. A Deep or Cavernous Hemangioma is a large, collection of blood vessels beneath the skin surface characterized by a soft, bluish, or skin colored mass. (findmeacure.com)
- A hemangioma is a non-cancerous growth that develops due to an unusual build-up of blood vessels . (firstaidcprvictoria.ca)
20231
- Cite this: Study Spotlights Characteristics of Infantile Hemangiomas With Aggressive Ulcerations - Medscape - Oct 31, 2023. (medscape.com)
Cavernous hemangioma of the liver2
- Other types of hemangioma include cavernous hemangiomas such as cavernous hemangioma of the liver. (wikipedia.org)
- Fischer AK, Beckurts KTE, Büttner R, Drebber U. Giant cavernous hemangioma of the liver with satellite nodules: Aspects on tumour/tissue interface: A case report. (wjgnet.com)
Tumors8
- Hemangiomas are benign (noncancerous) vascular tumors, and many different types occur. (wikipedia.org)
- However, several recent studies examining the genetics of cherry hemangiomas provide strong evidence that they are benign neoplasms, as they frequently harbor mutations known to cause other types of tumors. (logicalimages.com)
- The term hemangioma has been commonly used to describe a large number of vasoformative tumors. (medscape.com)
- With this concept in mind, this article discusses oral vasoformative tumors under the broad and not entirely correct term oral hemangiomas. (medscape.com)
- This scheme is straightforward and essentially divides the vasoformative tumors into 2 broad groups: hemangiomas and vascular malformations (see Table 1 below). (medscape.com)
- Hemangiomas are commonly classified as benign tumors, and are typically present either at birth, or develop over the first few months of life. (michelegreenmd.com)
- Miami, Fla. - Of the two types of vascular tumors-hemangiomas and vascular malformations-hemangiomas are the most common among children. (dermatologytimes.com)
- Dogs and cats with solar-induced hemangiomas may develop new hemangiomas (or other solar-induced tumors) at other sites of sun-damaged skin, potentially requiring additional surgeries to remove them. (vin.com)
Malformations6
- Hemangiomas exhibit both a proliferating phase and an involuting phase, whereas vascular malformations are more stable and fail to regress. (medscape.com)
- PHACE(S) (posterior fossa brain malformations, hemangiomas of the face [large or complex], arterial anomalies, cardiac anomalies, and eye abnormalities): The association is referred to as PHACE(S) when ventral developmental defects, such as sternal clefting or supraumbilical raphe, are present. (medscape.com)
- If your child has a large hemangioma on the face, scalp or neck, they are at risk for PHACE Syndrome, which links a series of vascular, endocrine, and neural abnormalities and malformations. (michelegreenmd.com)
- Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. (ufrgs.br)
- By their structure, vascular malformations are different than hemangiomas, and require specialized care in selecting treatment. (hemangiomatreatment.com)
- Examples of permanent malformations include Port-wine stains (capillary vascular malformation) and masses of abnormal swollen veins (venous malformations).Hemangiomas and Vascular Malformations in Infants and Children: A Classification Based on Endothelial Characteristics. (findmeacure.com)
Lobular capillary3
- Lobular capillary hemangioma (pyogenic granuloma) - Larger size, friable surface, and ulceration are more common in lobular capillary hemangioma compared to cherry hemangioma. (logicalimages.com)
- A lobular capillary hemangioma can sometimes be referred to as a "pregnancy tumor" due to their common development in the nose and mouth during a pregnancy. (michelegreenmd.com)
- lymphangioma , angiokeratoma , lobular capillary hemangioma (pyogenic granuloma). (librepathology.org)
Tumor6
- A hemangioma or haemangioma is a usually benign vascular tumor derived from blood vessel cell types. (wikipedia.org)
- Infantile hemangiomas are the most common benign tumor found in children. (wikipedia.org)
- Orbital hemangioma - A relatively large intraconal tumor seen on axial and coronal CT images. (eyecancer.com)
- Involution is then aborted, and a residual tumor virtually indistinguishable from non-involuting congenital hemangioma remains. (orpha.net)
- Infantile hemangioma is a common vascular tumor that affects infants and young children. (pharmacytimes.com)
- Hemangiomas are the most common childhood tumor occurring in approximately ten percent of Caucasians, and are less prevalent in other races. (findmeacure.com)
Lesion8
- The most devastating ophthalmic complication of hemangiomas relates to their ability to cause deprivation amblyopia in the affected eye if the lesion is large enough to directly occlude the visual axis. (medscape.com)
- A rare congenital hemangioma characterized by a superficial, red to violaceous lesion with overlying telangiectasia and a surrounding pale halo, which initially behaves like a rapidly involuting congenital hemangioma, beginning to involute shortly after birth. (orpha.net)
- Though the guidelines state there is no secret formula for knowing when and how to treat, they do stipulate that a hemangioma SHOULD BE TREATED based upon the amount of skin involved, location of lesion, severity of complications, and potential adverse psychosocial consequences. (birthmark.org)
- Again, parents have a right to have the hemangioma treated if they feel that leaving the lesion may result in physical or psychosocial issues for the child. (birthmark.org)
- Surgery is used when the lesion does not respond to other therapies or when it is severely problematic and there is no time to wait for the hemangioma to shrink. (birthmark.org)
- Subcutaneous Neck Lesion, Left, Excision: - Cavernous hemangioma. (librepathology.org)
- Treatment of hemangioma depends of patient's and characteristic of the lesion. (bvsalud.org)
- The aim of this paper is to report a hemangioma into cheek in which the treatment was the excision of the lesion. (bvsalud.org)
Superficial4
- mixed hemangiomas may have colors of both superficial and deep. (wikipedia.org)
- Small superficial hemangiomas will often disappear on their own. (medlineplus.gov)
- In the case of a combination Hemangioma, the vascular anomaly is deep within the dermis, and a superficial stain will appear on the surface of the skin. (michelegreenmd.com)
- 3. A Combined Hemangioma is a combination of a deep and superficial (strawberry) hemangioma. (findmeacure.com)
Congenital hemangioma1
- if one is visible at the time a child is born, it is referred to as a congenital hemangioma. (michelegreenmd.com)
Involute3
- Most true hemangiomas involute with time, but a certain small percentage do not, which may present with complications that require treatment (see Complications). (medscape.com)
- An estimated 10-20% of true hemangiomas incompletely involute and require postadolescent ablative treatment. (medscape.com)
- Typically, a hemangioma will slowly fade away or involute (turn inward), fully fading from the skin when a patient is between 5-10 years of age. (michelegreenmd.com)
Pathologic entities1
- Hemangiomas of the oral cavity are not common pathologic entities, but, among hemangiomas, the head and the neck are common sites. (medscape.com)
Hepatic2
- A cavernous liver hemangioma or hepatic hemangioma is a benign tumour of the liver composed of hepatic endothelial cells. (wikipedia.org)
- Several subtypes exist, including the giant hepatic hemangioma, which can cause significant complications. (wikipedia.org)
Remove a hemangioma2
- Doctors don't usually do surgery to remove a hemangioma because that can leave a scar. (merckmanuals.com)
- Laser removal - this is used by a doctor to remove a hemangioma. (firstaidcprvictoria.ca)
Liver5
- Liver hemangiomas are thought to be congenital in origin. (wikipedia.org)
- I have multiple (Two) haemangioma in right lobe of liver size 17X14 mm, since 2009. (abchomeopathy.com)
- In general, if a patient has six or more hemangiomas, they may be at risk for internal organ issues, particularly with the liver. (michelegreenmd.com)
- Hemangiomas of the liver are dealt with in the article liver hemangioma . (librepathology.org)
- Hemangiomas that develop on the liver rarely cause any symptoms. (firstaidcprvictoria.ca)
Proliferation4
- Cherry hemangiomas (also known as cherry angiomas, Campbell de Morgan spots, and senile hemangiomas) are the most common type of acquired benign vascular proliferation and are composed of thin-walled, dilated capillaries. (logicalimages.com)
- Proliferative hemangiomas develop from a proliferation of the cells that line the blood vessel, known as endothelial cells. (michelegreenmd.com)
- however, several studies have suggested the importance of estrogen signaling in hemangioma proliferation. (findmeacure.com)
- Excisional biopsy showed a well-circumscribed, benign vascular proliferation, consistent with a cavernous hemangioma or cavernous venous malformation. (medscape.com)
Rapidly involuting1
- Those that shrink are known as rapidly involuting congenital hemangiomas (RICH) and go away quickly. (wikipedia.org)
Birthmark3
- One in ten children are born with a vascular birthmark, most being a hemangioma. (birthmark.org)
- An infantile hemangioma is a common vascular birthmark that usually has no complications and goes away on its own. (michelegreenmd.com)
- For a parent with a child with this birthmark, there is no increased risk of having a subsequent child with a hemangioma. (findmeacure.com)
Diagnosis3
- If corrective surgery is deferred until after the hemangioma has completely involuted, which is around age 10, insurance will routinely deny coverage because too much time has gone by since the diagnosis. (birthmark.org)
- Dr. Green's dermatology office is here to help for any concerns related to diagnosis and treatment of hemangiomas. (michelegreenmd.com)
- Histopathology is crucial for the correct diagnosis: while in angiokeratoma the vascular alterations are limited to the papillary dermis, verrucous hemangioma extends deep into the dermis, reaching the subcutaneous tissue. (ufrgs.br)
Term hemangioma2
- The term hemangioma described many lesions that bore little relationship to each other apart from their being involved with vessels. (medscape.com)
- The term hemangioma was originally used to describe any vascular tumour both present around birth or appearing later in life. (findmeacure.com)
Treat hemangiomas2
- How do doctors treat hemangiomas? (merckmanuals.com)
- Other treatments included use of external x-irradiation to treat hearing loss, acne, tinea capitis, enlarged adenoids, and enlarged thymus, and the use of topical radon and radium to treat hemangiomas. (cdc.gov)
Visceral hemangiomas1
- These patients characteristically present with a consumption coagulopathy and thrombocytopenia secondary to platelet sequestration in large visceral hemangiomas. (medscape.com)
Strawberry hemangioma1
- strawberry hemangioma a circumscribed capillary hemangioma, which may be present at birth or may appear soon after birth. (imedpub.com)
Infantile haemangioma3
- To describe the use of propranolol as first-line treatment or as single therapy to control the proliferating phase of infantile haemangioma in Chinese children. (hkmj.org)
- Propranolol was useful as first-line or single-agent treatment of facial infantile haemangioma in Chinese children, and gave rise to minimal side-effects. (hkmj.org)
- Although recurrence of infantile haemangioma occurred after propranolol was tailed off rapidly after a relatively short duration, an optimal treatment duration and tapering schedule has not yet been defined. (hkmj.org)
Occur4
- A hemangioma can occur anywhere on the body, but most commonly appears on the face, scalp, chest or back. (wikipedia.org)
- A hemangioma may occur with other rare conditions. (medlineplus.gov)
- Usually hemangiomas occur in the first few weeks of infancy and self-dissolve in the first decade. (oatext.com)
- Although hemangiomas are benign, some serious complications can occur. (findmeacure.com)
Birthmarks2
- All birthmarks, including hemangiomas, should be evaluated by your provider during a regular exam. (medlineplus.gov)
- Hemangiomas are one of the most common birthmarks in newborns. (findmeacure.com)
Tumour1
- Hemangioma is a very common benign vascular tumour . (librepathology.org)
Intramuscular5
- Pathology studies verified the mass was an intramuscular hemangioma involving the extensor digitorum longus, extensor hallucis longus, and tibialis anterior muscles. (oatext.com)
- To the author's knowledge, such an excision of an intramuscular hemangioma extending into three muscles of this location has not been presented in the literature. (oatext.com)
- Intramuscular hemangiomas are very rare, accounting for less than 1% of all hemangiomas. (oatext.com)
- Intramuscular hemangiomas may be of 3 types: capillary, cavernous, or mixed. (oatext.com)
- Intramuscular hemangiomas do not have nuclear hyperchromatism nor do they develop the freely anastomosing sinusoidal pattern as seen in certain angiosarcomas. (oatext.com)
Oral propranolol2
- Children 3 years old or younger with facial haemangioma who took oral propranolol between 1 December 2008 and 1 December 2009. (hkmj.org)
- Conclusion The use of oral atenolol compared with oral propranolol as monotherapies may result in little or no difference in terms of likelihood of complete remission, decrease in Hemangioma Activity Score, likelihood of post- treatment relapse , and risk of adverse events and severe adverse events, in infantile hemangioma (low certainty of evidence). (bvsalud.org)
Venous malformation1
- 1. What is a cavernous-hemangioma or cavernous venous malformation of the orbit? (medscape.com)
Endothelial3
- Title : A Hydrogel-Endothelial Cell implant Mimics Infantile Hemangioma: Modulation by Survivin and the Hippo pathway* Personal Author(s) : Tsuneki, Masayuki;Hardee, Steven;Michaud, Michael;Morotti, Raffaella;Lavik, Erin;Madri, Joseph A. (cdc.gov)
- Microvascular endothelial cells cultured in three-dimensional hydrogel scaffolds form a network of microvessel structures when implanted subcutaneously in mice, inosculate with host vessels, and over time remodel into large ectatic vascular structures resembling hemangiomas. (cdc.gov)
- Hemangioma is clinical term for designate a benign vascular neoplasm or vascular malformation of endothelial origin. (bvsalud.org)
Shrink and go away2
- Congenital hemangiomas are classified according to whether they shrink and go away, or do not shrink, and do not go away, or partially shrink. (wikipedia.org)
- Most hemangiomas shrink and go away on their own. (merckmanuals.com)
Propranolol4
- Oral beta blockers such as propranolol or atenolol have been used since 2008 and are the first-line treatment of hemangiomas. (wikipedia.org)
- Hemangeol, a propranolol-based oral solution, has emerged as a groundbreaking treatment for infantile hemangiomas, providing a safe and effective therapeutic option for pediatric patients. (pharmacytimes.com)
- Hemangeol, a beta-blocker that contains propranolol, was approved by the FDA in 2014 as the first and only pharmacological treatment for infantile hemangioma. (pharmacytimes.com)
- Sin embargo, aún existe controversia en relación con la eficacia y seguridad del tratamiento con atenolol como monoterapia, en comparación con el uso de propranolol como monoterapia para esta condición. (bvsalud.org)
Infants4
- The most common form, seen in infants, is an infantile hemangioma, known colloquially as a "strawberry mark", most commonly presenting on the skin at birth or in the first weeks of life. (wikipedia.org)
- Caucasian, female, low-birthweight / premature infants are the most likely to present with a hemangioma. (michelegreenmd.com)
- Infants tend to have a small amount of lesions but, according to the Boston Children's Hospital Vascular Anomalies Center, some infants can develop several hundred lesions with this type of hemangioma classification. (michelegreenmd.com)
- A hemangioma that develops on the skin appear as small-sized scratches on infants and grow wide as the child ages. (firstaidcprvictoria.ca)
Internal organs2
- Depending on the location of the hemangioma, tests such as MRIs or ultrasounds can be done to see how far the hemangioma goes under the skin and whether it affects any internal organs. (wikipedia.org)
- Take note that there are no known measures to prevent the growth of a hemangioma on the skin or internal organs. (firstaidcprvictoria.ca)
Surgical2
- Before the emergence of Hemangeol, the treatment of infantile hemangiomas primarily involved surgical procedures, laser therapy, or corticosteroids, each with its limitations and potential adverse effects. (pharmacytimes.com)
- Surgical outcomes of transconjunctival anterior orbitotomy for intraconal orbital cavernous hemangioma. (medscape.com)
Pathology1
- Pathology confirmed mass as a cavernous hemangioma. (medscape.com)
Soft tissue2
- This combination classification is defined based on the amount of soft tissue involved in the hemangioma. (michelegreenmd.com)
- Hemangiomas are the most common benign soft tissue mass in children under age ten. (oatext.com)
Treatment11
- Hemangiomas usually fade gradually over time, and many do not require treatment. (wikipedia.org)
- However, hemangiomas that may be disfiguring or that are located at sites that can cause impairment (eyelids, airway) require early treatment intervention, typically with beta blockers. (wikipedia.org)
- The majority of small or uncomplicated hemangiomas may not need treatment. (medlineplus.gov)
- Also dr. told me i have IBS .I am looking for homeopathy treatment for Haemangioma & IBS. (abchomeopathy.com)
- Cherry hemangiomas are benign and thus do not require treatment unless irritated or bleeding (usually secondary to trauma), but are often of cosmetic concern to patients. (logicalimages.com)
- Two of them had a recurrence of the haemangioma within 8 weeks of stopping the drug, but responded to a second treatment course. (hkmj.org)
- VBF pushes for early and appropriate treatment as soon as a hemangioma is diagnosed to prevent future complications - both physical and psychosocial. (birthmark.org)
- Thankfully, a huge percentage of hemangiomas are very small, hidden in hair or obscure locations, and need no treatment. (birthmark.org)
- Dr. Green is available to examine any infantile hemangiomas and discuss treatment options for unsightly or disfiguring hemangiomas. (michelegreenmd.com)
- Once a benign hemangioma is removed surgically, your pet usually requires no additional treatment and is back to normal health. (vin.com)
- A single, small-sized hemangioma does not require any treatment and likely to vanish on its own. (firstaidcprvictoria.ca)
Cranial2
- To date, diffuse cranial hemangioma of skull has not been reported. (biomedcentral.com)
- Diffuse cranial hemangioma has not yet been reported. (biomedcentral.com)
Splenic2
- Yonso M, Splenic hemangioma. (radiopaedia.org)
- Splenic hemangioma presenting as a 'hot spot' on radiocolloid scintigraphy. (mcmaster.ca)
Epithelioid1
- Epithelioid hemangioma - see angiolymphoid hyperplasia with eosinophilia‎ . (librepathology.org)
Cherry angiomas1
- Adults can get hemangiomas (these are often called cherry angiomas). (merckmanuals.com)
Proliferative phase1
- After this proliferative phase, most hemangiomas enter a slow involution phase, eventually resolving without intervention. (pharmacytimes.com)
Symptoms2
- What are the symptoms of hemangiomas? (merckmanuals.com)
- Nevertheless, they might instigate some symptoms if they enlarge in size, there are several hemangiomas or if they develop in a sensitive region. (firstaidcprvictoria.ca)
Orbital3
- Zauberman H, Feinsod M. Orbital hemangioma growth during pregnancy. (medscape.com)
- Liu X, Xu D, Zhang Y, Liu D, Song G. Gamma Knife surgery in patients harboring orbital cavernous hemangiomas that were diagnosed on the basis of imaging findings. (medscape.com)
- Extirpation of an orbital cavernous hemangioma. (medscape.com)
Juvenile3
- They now are thought to be of placental origin due to a unique microvascular phenotype shared by juvenile hemangiomas and human placenta. (medscape.com)
- Infantile hemangioma (AKA juvenile hemangioma [4] ) - these tumours are GLUT-1 +ve. (librepathology.org)
- GLUT1: a newly discovered immunohistochemical marker for juvenile hemangiomas. (librepathology.org)
Regress1
- Dermatologists treating these patients should know that while the vast majority of hemangiomas regress spontaneously, without problems, lesions that are segmental, multiple, giant or in certain locations on the body are of great concern. (dermatologytimes.com)
Etiology1
- The etiology of cherry hemangiomas is still poorly understood, with evidence supporting either a reactive or a neoplastic underpinning. (logicalimages.com)
Periocular1
- Capillary hemangioma (infantile periocular hemangioma). (medscape.com)