Hemidesmus
Smilax
Effect of Fagonia Arabica (Dhamasa) on in vitro thrombolysis. (1/3)
BACKGROUND: Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed in blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the treatment of several diseases. Herbs and their components possessing antithrombotic activity have been reported before; however, herbs that could be used for thrombolysis has not been reported so far. This study's aim was to investigate whether herbal preparations (aqueous extract) possess thrombolytic activity or not. METHODS: An in vitro thrombolytic model was used to check the clot lysis effect of six aqueous herbal extracts viz., Tinospora cordifolia, Rubia cordifolia, Hemidesmus indicus, Glycyrrhiza glabra Linn, Fagonia Arabica and Bacopa monnieri Linn along with Streptokinase as a positive control and water as a negative control. RESULTS: Using an in vitro thrombolytic model, Tinospora cordifolia, Rubia cordifolia, Hemidesmus indicus, Glycyrrhiza glabra Linn, Fagonia Arabica and Bacopa monnieri Linn showed 19.3%, 14.5%, 20.3%, 17.8%, 75.6% and 41.8% clot lysis respectively . Among the herbs studied Fagonia arabica showed significant % of clot lysis (75.6%) with reference to Streptokinase (86.2%). CONCLUSION: Through our study it was found that Dhamasa possesses thrombolytic properties that could lyse blood clots in vitro; however, in vivo clot dissolving properties and active component(s) of Dhamasa for clot lysis are yet to be discovered. Once found Dhamasa could be incorporated as a thrombolytic agent for the improvement of patients suffering from Atherothrombotic diseases. (+info)Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug. (2/3)
(+info)Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects. (3/3)
(+info)"Hemidesmus" is a botanical term that refers to a plant species, rather than a medical condition or concept. The plant is known as Hemidesmus indicus, or Indian sarsaparilla, and it has been used in traditional Ayurvedic medicine for various health purposes such as treating skin diseases, rheumatism, and digestive issues.
The roots of the Hemidesmus indicus plant contain several chemical compounds with potential medicinal properties, including steroidal saponins, alkaloids, and phenolic compounds. However, there is limited scientific evidence to support many of the traditional uses of this plant, and further research is needed to establish its safety and efficacy in modern medical practice.
"Smilax" is a genus of flowering plants, also known as greenbriars. While "Smilax" itself is not a medical term, some species of this plant have been used in traditional medicine. For instance, the roots and rhizomes of Smilax aristolochiifolia (Mexican sarsaparilla) and Smilax ornata (Jamaican sarsaparilla) have been used in traditional herbal remedies for various health conditions, including skin diseases, rheumatism, and sexual impotence. However, it's important to note that the scientific evidence supporting these uses is generally weak, and these remedies may carry risks, such as allergic reactions or contamination with harmful substances. Always consult a healthcare provider before starting any new treatment.
"Nigella" is a term that refers to the seeds or oil derived from the Nigella sativa plant, also known as black cumin or fennel flower. The seeds and oil have been used in traditional medicine for various health purposes, such as treating digestive issues, respiratory conditions, and headaches. However, it is important to note that while some studies suggest potential health benefits of Nigella, more research is needed to confirm its effectiveness and safety.
Hemidesmus