Dermatitis, Photoallergic
Psoralens
Studies on cancer chemoprevention by traditional folk medicines XXIV. Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin, against tumor-promotion. (1/8)
7-Isopentenyloxycoumarin (1) was isolated from Heracleum lanatum MICHX. (Umbelliferae). Compound 1 inhibited phospholipid metabolism and Epstein-Barr virus activation caused by a potent tumor promoter. In an in vivo experiment, topical application of 1 suppressed skin-tumor-formation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in 7,12-dimethylbenz[a]anthracene (DMBA) initiated mice. And it also suppressed ornithine decarboxylase activity stimulated by TPA on mouse skin. These results indicated that 7-isopentenyloxycoumarin is one of the effective compounds from natural resources for treating skin tumor formation. (+info)The furanocoumarins in the roots of Heracleum sibiricum L. (2/8)
From roots of Heracleum sibiricum L (cow parsnip) collected natural state, a raw crystalline furanocoumarin precipitate was obtained containing four compounds: bergapten, isopimpinellin, pimpinellin, sphondin. The isolated compounds were identified with H1NMR. (+info)Four coumarins from Heracleum yunngningense. (3/8)
Four new coumarins (1-4) were isolated from the roots of Heracleum yunngningense HAND.-MASS. Their structures were established by spectral analyses. (+info)Allelic variation in the Depressaria pastinacella CYP6AB3 protein enhances metabolism of plant allelochemicals by altering a proximal surface residue and potential interactions with cytochrome P450 reductase. (4/8)
CYP6AB3v1, a cytochrome P450 monooxygenase in Depressaria pastinacella (parsnip webworm), is highly specialized for metabolizing imperatorin, a toxic furanocoumarin in the apiaceous host plants of this insect. Cloning and heterologous expression of CYP6AB3v2, an allelic variant identified in D. pastinacella, reveals that it metabolizes imperatorin at a rate (V(max) of 10.02 pmol/min/pmol of cytochrome P450 monooxygenase (P450)) significantly higher than CYP6AB3v1 (V(max) of 2.41 pmol/min/pmol) when supplemented with even low levels of cytochrome P450 reductase. Comparisons of the NADPH consumption rates for these variants indicate that CYP6AB3v2 utilizes this electron source at a faster rate than does CYP6AB3v1. Molecular modeling of the five amino acid differences between these variants and their potential interactions with P450 reductase suggests that replacement of Val(92) on the proximal face of CYP6AB3v1 with Ala(92) in CYP6AB3v2 affects interactions with P450 reductase so as to enhance its catalytic activity. Allelic variation at this locus potentially allows D. pastinacella to adapt to both intraspecific and interspecific variation in imperatorin concentrations in its host plants. (+info)Results of a randomized,open-label,clinical trial investigating the effects of supplementation with Heracleumpersicum extract as an adjunctive therapy for dyslipidemia. (5/8)
(+info)Pressurized liquid extraction of coumarins from fruits of Heracleum leskowii with application of solvents with different polarity under increasing temperature. (6/8)
(+info)Heracleum Sosnowskyi Manden. (7/8)
Heracleum Sosnowskyi was discovered in 1772 and described as a separate species in 1944 by I. P. Mandenova. Its name is derived from the surname of a botanist studying Caucasian flora, Prof. D.I. Sosnowski. In the area of the Caucasus foothills, the plant reaches approximately 1-1,5 m in height, whereas in Poland its size is significantly larger, up to 3-3.5 m. Heracleum blooms from mid-June to the end of July. The flowers are arranged in umbels and last for 2-3 weeks. In Central Europe, the species colonizes mostly neglected green areas, ruins and riversides. Heracleum poses a serious threat to the human population due to its photoallergic properties, resulting from the presence of intensely toxic furanocoumarin in its sap. Furanocoumarins are found in small hairs that cover the leaves and stem, and are the components of the essential oil. They may penetrate the skin through the epithelial layer, posing a direct threat to human health. Contact with the plant, followed by sun exposure, may lead to the development of large blisters and symptoms of burns. Heracleum, in the event of consumption, is also harmful to farm animals, causing, among others, internal bleeding and diarrhea. Although the toxic properties of Heracleum have been known for many years, every summer people who had contact with the plant present at physicians of different medical specialties. (+info)Genome drafts of four phytoplasma strains of the ribosomal group 16SrIII. (8/8)
(+info)"Heracleum" is a genus of plants in the family Apiaceae, also known as the carrot or parsley family. Many species in this genus are large herbaceous plants native to Europe and Asia, with some found in North America. One well-known species is Heracleum persicum, commonly called "giant hogweed," which can grow up to 15 feet tall and has been identified as an invasive species in certain regions.
The sap of giant hogweed contains toxic compounds that can cause phytophotodermatitis, a skin reaction characterized by redness, pain, itching, and blistering when the affected area is exposed to sunlight. This reaction can be severe and may result in scarring or long-term sensitivity to light. It's essential to exercise caution when handling or coming into contact with giant hogweed or any other members of the Heracleum genus.
In a medical context, it's crucial to differentiate between 'Heracleum' as a plant genus and 'heracleum' as a term used in anatomy. In anatomy, 'heracleum' refers to a muscle in certain animals, specifically the external abdominal oblique muscle in ruminants like cows and sheep. However, this usage is not directly related to human medicine or healthcare.
Photoallergic dermatitis is a type of contact dermatitis that occurs as a result of an allergic reaction to a substance after it has been exposed to ultraviolet (UV) light. This means that when the substance (allergen) comes into contact with the skin and is then exposed to UV light, usually from the sun, an immune response is triggered, leading to an inflammatory reaction in the skin.
The symptoms of photoallergic dermatitis include redness, swelling, itching, and blistering or crusting of the skin. These symptoms typically appear within 24-72 hours after exposure to the allergen and UV light. The rash can occur anywhere on the body but is most commonly found in areas that have been exposed to the sun, such as the face, neck, arms, and hands.
Common allergens that can cause photoallergic dermatitis include certain medications, fragrances, sunscreens, and topical skin products. Once a person has become sensitized to a particular allergen, even small amounts of it can trigger a reaction when exposed to UV light.
Prevention measures for photoallergic dermatitis include avoiding known allergens, wearing protective clothing, and using broad-spectrum sunscreens that protect against both UVA and UVB rays. If a reaction does occur, topical corticosteroids or oral antihistamines may be prescribed to help relieve symptoms.
Psoralens are a class of organic compounds that can be found in several plants such as figs, celery, and parsnips. They are primarily known for their use in the treatment of skin conditions like psoriasis and eczema. When combined with ultraviolet A (UVA) light therapy, psoralens can help to slow down the excessive growth of skin cells that lead to these conditions.
Psoralens work by intercalating into DNA, which means they fit between the base pairs of the double helix structure of DNA. When exposed to UVA light, the psoralen molecules undergo a chemical reaction that forms cross-links in the DNA, which can inhibit the replication and transcription of DNA. This effect on skin cells can help to reduce inflammation and slow down the growth of affected skin cells, leading to an improvement in symptoms of certain skin conditions.
It's important to note that psoralens can have side effects, including increased sensitivity to sunlight, which can lead to sunburn and an increased risk of skin cancer with long-term use. Therefore, it's essential to follow the instructions of a healthcare provider carefully when using psoralen therapy.
Heracleum
Heracleum mantegazzianum
Heracleum sphondylium
Heracleum maximum
Heracleum (plant)
Heracleum sosnowskyi
Heracleum sibiricum
Heracleum dissectum
Heracleum persicum
List of largest inflorescences
Tetrataenium nepalense
Borscht
Angelica archangelica
Autonym (botany)
Belvoir Park Forest
Agonopterix caucasiella
Pammene aurana
Iris orjenii
Native American ethnobotany
Ida P. Mandenova
Third Macedonian War
Phytophotodermatitis
Epinotia majorana
Agonopterix flavicomella
List of wort plants
Rhagonycha fulva
Meiosimyza rorida
Furanocoumarin
Aethes dilucidana
Angelicin
Heracleum - Wikipedia
Heracleum sosnowskyi Manden.
Heracleum yunnanense - Wikispecies
Heracleum Sphondylium relationships - ABC Homeopathy
Heracleum species ?- Chakrata - efloraofindia
Heracleum polyadenum in Flora of Pakistan @ efloras.org
Moooi Heracleum III Small Suspended by Bertjan Pot | Design Public
CalPhotos: Heracleum maximum; Cow Parsnip
Heracleum III The Big O Pendant - Design Within Reach
Heracleum sphondylium - Scathophagidae Flower Visitors
Moooi Heracleum III Suspended pendant, large, copper | Finnish Design Shop UK
Giant Hogweed (Heracleum Mantegazzianum) - Glenlivet Wildlife
Heracleum III Small Big O Suspension Light by Moooi - Switch Modern
Italian Pronunciation - Heracleum
Heracleum details | skylinegardensebcnps
Italian Pronunciation - Heracleum
Heracleum - Beat Haldemann
Heracleum maximum - Butterflies
German Pronunciation - Heracleum
Ukrainian Pronunciation - Heracleum
Heracleum sosnowskyi [Manden., 1944 ]
TROUSERS HERACLEUM BLUE - D'AUTAN
Wolley's Dodo - Heracleum Palindrome
Heracleum mantegazzianum Sommier & Levier - idseed
2008 February - Archivio - Heracleum Pages
Moooi3
- Heracleum by MOOOI is the modern suspension lamp in Small and Large sizes designed by Bertjan Pot. (accaduehome.com)
- Buy MOOOI Small or Large Heracleum III at the outlet price and request the reserved offer for the suspension lamp designed by Bertjan Pot. (accaduehome.com)
- A perpetual blossom of new branches that multiplies by the meter, Heracleum III Endless Pendant Light by Bertjan Pot for Moooi may really grow out of reach! (studiocomo.com)
Bertjan Pot3
- Nature meets technology in Heracleum III Suspended by Bertjan Pot. (designpublic.com)
- Designed by Bertjan Pot, Heracleum is included in the collection of the Stedelijk Museum Amsterdam. (dwr.com)
- Designed by Bertjan Pot, the delicate pendant is a fascinating combination of nature and technical innovation: Heracleum III consists of a metal frame decorated with illuminated polycarbonate discs reminiscent of leaves or blossoms. (finnishdesignshop.com)
Apiaceae1
- Home » Species » Plantae » Magnoliophyta » Rosopsida » Apiales » Apiaceae » Heracleum » Heracleum sosnowskyi - Manden. (myspecies.info)
Sphondylium2
- Below are the main rubriks (i.e strongest indications or symptoms) of Heracleum Sphondylium in traditional homeopathic usage , not approved by the FDA. (abchomeopathy.com)
- Heracleum sphondylium L. subsp. (plazi.org)
Mantegazzianum2
- Giant Hogweed (Heracleum mantegazzianum) is an extremely invasive weed that poses significant risks to both human health and the environment. (glenlivet-wildlife.co.uk)
- Phytophotodermatitis from Heracleum mantegazzianum. (medscape.com)
Genus2
- Heracleum may mean The plant genus Heracleum (plant) An alternative spelling of Herakleion, the capital of Crete in Greece An alternative spelling of Heraklion, various places with that name An alternative spelling of Heracleium, various places with that name Heracleium (disambiguation) Heraklion (disambiguation) Heracles This disambiguation page lists articles associated with the title Heracleum. (wikipedia.org)
- Giant Hogweed belongs to the Heracleum genus and is native to the Caucasus region. (glenlivet-wildlife.co.uk)
Marcel Wanders3
- The white leaves in Heracleum III Suspended ramify from one branch, creating a very technical, natural structure thanks to a technique of coating conductive layers called Electrosandwich by Marcel Wanders studio. (designpublic.com)
- In order to achieve the Heracleum light's novel aesthetic, the designer credits fellow designer, Marcel Wanders, with developing the technology to enable it. (switchmodern.com)
- Like the other designs in the Heracleum family, the lean branches are powered by Electrosandwich, by Marcel Wanders studio. (rypen.com)
Parsnip1
- Pot's inspiration for the form came from nature - the ubiquitous Heracleum plant often referred to as cow parsnip or hogweed. (switchmodern.com)
Manden2
- Heracleum sosnowskyi Manden. (gbif.org)
- Heracleum grossheimii Manden. (idseed.org)
Species1
- Heracleum alpinum Linnaeus , Species Plantarum 1: 250. (plazi.org)
20231
- https://www.plantarium.ru/lang/en/page/image/id/165353.html (accessed on 29 Nov 2023). (plantarium.ru)
Sibiricum2
- 2012. Изображение Heracleum sibiricum L. // Плантариум. (plantarium.ru)
- Image of Heracleum sibiricum L. // Plantarium. (plantarium.ru)
Pendant light3
- Moooi's Heracleum III Suspended pendant light draws inspiration from the natural world, more specifically from the unique shape of hogweed plants. (finnishdesignshop.com)
- The Heracleum Small Big O pendant light is part of Bertjan Pot's stunning Heracleum collection. (hollowaysofludlow.com)
- Sophisticated and truly unique, the Heracleum Small Big O pendant light will make an elegant addition to any contemporary space. (hollowaysofludlow.com)
Chandelier2
- Heracleum is a very decorative chandelier, inspired by the plant that bears the same name from the characteristic flowering with white petals. (accaduehome.com)
- Inspired by the Heracleum plants, the opulent Heracleum Chandelier has a contemporary and unique design. (jainsonsemporio.com)
Plant3
- Nature meets technology, as this LED lamp is inspired by the Heracleum Plant. (elegantliving.bg)
- The Heracleum III Linear, available in four colors, is inspired by the flowering plant of the same name. (rypen.com)
- The Replica Heracleum Pendant in Black is a thin and delicate decorative LED lamp design inspired by the Heracleum plant. (crystalpalacelighting.com.au)
Electrosandwich1
- The Heracleum III Linear is a design not possible with normal wires - it's powered by Electrosandwich, a technique of coating conductive layers. (rypen.com)
Lamps3
- The most beautiful lamps inspired by designer projects include those of the Heracleum type. (inspirowane.eu)
- If the ready lamps inspired by Heracleum meet your expectations, place your order now - we guarantee efficient execution of your order. (inspirowane.eu)
- The original composition of the Heracleum type lamps is based on round leaves, placed on a light copper structure. (inspirowane.eu)
Blossom2
- A perpetual blossom of branches, there is hardly a limit to what Heracleum can now achieve by developing in straight lines, hanging in circles and forming square geometric shapes. (rypen.com)
- With its delicate lines and timeless colors, there's no space or interior where Heracleum can't blossom. (rypen.com)
Design2
- The Heracleum light is a remarkable design that is truly an example of the intersection of technology and art. (switchmodern.com)
- Contact the shop for a completely unique Heracleum lamp design for a restaurant, hotel or home. (inspirowane.eu)
Colors2
- Heracleum III Linear is available in 4 colors. (rypen.com)
- Heracleum III Suspended comes in two sizes and four different colors. (molecule-design-online.com)
Consists1
- The majestic Heracleum III The Big O Pendant (2014) consists of dimmable LEDs embedded in leaf-shaped polycarbonate lenses attached to slim metal stems to create a natural-looking form. (dwr.com)
Frozen1
- The Heracleum leaves are not frozen in one position. (uniquedesign.biz)
Technical1
- New: Heracleum includes a new LED that allows endless technical possibilities, making this new version much more efficient while providing unique and sparkling illumination. (molecule-design-online.com)
Side1
- With its upward sweeping blossoms on either side, the Heracleum III Linear is perfect for intimate rectangular spaces. (rypen.com)
Small2
- Noted here is Heracleum Small Big O, a smaller round version of its dramatic Big O cousin. (switchmodern.com)
- Heracleum has a circular shape with a diameter of 72 cm in the small size and 98 cm in the Large version and has a metal wire structure. (accaduehome.com)
Sizes1
- Heracleum III Suspended comes in two sizes and four different colours. (designpublic.com)