Histiocytoma, Benign Fibrous
Histiocytoma, Malignant Fibrous
Histiocytoma
Soft Tissue Neoplasms
Histiocytic Sarcoma
Sarcoma
Liposarcoma
Retroperitoneal Neoplasms
Femoral Neoplasms
Angiomatosis
Myxosarcoma
Piezosurgery
Vascular Neoplasms
Heart Neoplasms
Tracheobronchomegaly
Fatal Outcome
Dog Diseases
Neoplasm Regression, Spontaneous
Giant Cell Tumors
Histiocytes
Maxillary Sinus Neoplasms
Immunohistochemistry
Dermatofibrosarcoma
Tomography, X-Ray Computed
Osteosarcoma
Cystadenocarcinoma
Leiomyosarcoma
Neoplasms, Multiple Primary
Chondrosarcoma
Nerve tolerance to high-dose-rate brachytherapy in patients with soft tissue sarcoma: a retrospective study. (1/10)
BACKGROUND: Brachytherapy, interstitial tumor bed irradiation, following conservative surgery has been shown to provide excellent local control and limb preservation in patients with soft tissue sarcomas (STS), whereas little is known about the tolerance of peripheral nerves to brachytherapy. In particular, nerve tolerance to high-dose-rate (HDR) brachytherapy has never been properly evaluated. In this study, we examined the efficacy and radiation neurotoxicity of HDR brachytherapy in patients with STS in contact with neurovascular structures. METHODS: Between 1995 and 2000, seven patients with STS involving the neurovascular bundle were treated in our institute with limb-preserving surgery, followed by fractionated HDR brachytherapy. Pathological examination demonstrated that 6 patients had high-grade lesions with five cases of negative margins and one case with positive margins, and one patient had a low-grade lesion with a negative margin. Afterloading catheters placed within the tumor bed directly upon the preserved neurovascular structures were postoperatively loaded with Iridium-192 with a total dose of 50 Gy in 6 patients. One patient received 30 Gy of HDR brachytherapy combined with 20 Gy of adjuvant external beam radiation. RESULTS: With a median follow-up of 4 years, the 5-year actuarial overall survival, disease-free survival, and local control rates were 83.3, 68.6, and 83.3%, respectively. None of the 7 patients developed HDR brachytherapy-induced peripheral neuropathy. Of 5 survivors, 3 evaluable patients had values of motor nerve conduction velocity of the preserved peripheral nerve in the normal range. CONCLUSION: In this study, there were no practical and electrophysiological findings of neurotoxicity of HDR brachytherapy. Despite the small number of patients, our encouraging results are valuable for limb-preserving surgery of unmanageable STS involving critical neurovascular structures. (+info)Progressive nodular histiocytoma associated with thrombocytopenia with absent radii (TAR syndrome) and angiofibromas. (2/10)
A 50-year-old woman was admitted due to a long-standing history of cutaneous lesions, which were gradually increasing in number and size, located on the trunk and extremities. Histological studies confirmed the initial clinical diagnosis of histiocytomas. Moreover, the patient had numerous smooth erythematous papules on her chin and around her nose, which were diagnosed histologically as angiofibromas. The patient had congenital phocomelia. Analytical and imaging studies revealed the presence of bilateral phocomelia due to absent radii and thrombocytopenia (TAR syndrome). Multiple histiocytomas in a normolipaemic patient bring up several differential diagnoses. Slow progressive evolution without spontaneous resolution and a scattered distribution on the trunk and extremities suggest the diagnosis of progressive nodular histiocytoma. To our knowledge progressive nodular histiocytoma has not been reported previously associated either with TAR syndrome or with angiofibromas. These entities are uncommon, thus their association may not be due to chance. (+info)Clinico-imaging and anatomopathologic correlations in sarcomas of maxilla. (3/10)
Sarcomas are relatively uncommon tumors, accounting for 1% of all malignancies. Sarcomas are commonly classified according to their site of origin: soft tissues or bone. The purpose of the clinic study was to focus the symptoms and the clinic signs. The radio-imaging study is essential in the evaluation of the maxilla tumors. The histopathologic study was done to determine the histological type, the differentiation level, the invasion level as well as the presence or absence of the metastases in drainage ganglia. The correlation of the findings of this study leads to a clear and correct clinic diagnosis, an adequate local or general therapy and a prognostic. The diagnostic role of imaging is essential and often permits the orientation to benignity or, on the contrary, requires biopsy if the image is an aggressive one or of uncertain nature. Advances in diagnostic imaging have contributed substantially to the management of tumors. The strong collaboration among the physician, imaging personnel and anatomo-pathologist serves the patient's benefit. (+info)Review. Acridine orange could be an innovative anticancer agent under photon energy. (4/10)
Acridine orange (AO) was extracted as a dye from coal tar over a hundred years ago. It has various unique biological activities and has been shown to be a useful fluorescent dye specific for DNA and RNA, a pH indicator, photosensitizer, antitumor and antimalarial drug, and detector of bacteria and parasites. It has recently been found that AO accumulates in musculoskeletal sarcomas and that after illumination of the tumors with visible light or irradiation with low-dose X-rays, the dye rapidly exerts selective cytocidal effect against the sarcoma cells. Therefore, surgery combined with photo- (PDT) or radiodynamic therapy (RDT) with AO (AO-PDT and -RDT) has been applied to human musculoskeletal sarcomas. The results of a clinical study on the outcome of this therapeutic strategy revealed that it yielded better local control and remarkably better limb function than wide resectional surgery. Based on our experimental studies, it was clarified that AO accumulates in acidic organelles or structures, especially lysosomes, depending on the acidity. An enormous number of protons are produced in cancer from lactate or CO2 under hypoxic conditions, which are moved into the extracellular fluid or lysosomes to maintain the intracellularfluid pH. Therefore, AO shows marked accumulation in the acidic lysosomes of cancer cells. Photon energy from visible light or X-rays excites the AO accumulated in lysosomes; the excited AO emits fluorescence and forms activated oxygen from intra-cytoplasmic oxygen. The activated oxygen destroys lysosomes, with the released lysosomal enzymes causing rapid death of the cancer cells. On the other hand, normal cells can exclude AO quickly because they are not acidic. Thus, AO-PDT and AO-RDT exhibit strong and selective cytocidal effect against malignant tumors. In conclusion, we believe that AO-PDT and AO-RDT exhibit selective anticancer cell activity and that AO excited by photon energy has excellent potential as an anticancer agent. (+info)Heat shock transcription factors regulate heat induced cell death in a rat histiocytoma. (5/10)
Heat shock response is associated with the synthesis of heat shock proteins (Hsps) which is strictly regulated by different members of heat shock transcription factors (HSFs). We previously reported that a rat histiocytoma, BC-8 failed to synthesize Hsps when subjected to typical heat shock conditions (42 degrees C, 60 min). The lack of Hsp synthesis in these cells was due to a failure in HSF1 DNA binding activity. In the present study we report that BC-8 tumor cells when subjected to heat shock at higher temperature (43 degrees C, 60 min) or incubation for longer time at 42 degrees C, exhibited necrosis characteristics; however,under mild heat shock (42 degrees C, 30 min) conditions cells showed activation of autophagy. Mild heat shock treatment induced proteolysis of HSF1, and under similar conditions we observed an increase in HSF2 expression followed by its enhanced DNA binding activity. Inhibiting HSF1 proteolysis by reversible proteasome inhibition failed to inhibit heat shock induced autophagy. Compromising HSF2 expression but not HSF1 resulted in the inhibition of autophagy, suggesting HSF2 dependent activation of autophagy. We are reporting for the first time that HSF2 is heat inducible and functions in heat shock induced autophagic cell death in BC-8 tumor cells. (+info)Radiologic findings in a patient with frontal parafalcine dendritic cell histiocytoma. (6/10)
We report the case history and radiologic findings of a patient with a biopsy-proven dendritic cell histiocytoma presenting as a single intracranial extra-axial mass and no systemic disease. Even though this entity is relatively rare, it should nevertheless be considered in the differential diagnosis of dural-based space-occupying central nervous system lesions. (+info)Canine histiocytic neoplasia: an overview. (7/10)
Canine histiocytic neoplasms include cutaneous histiocytoma, as well as localized and disseminated histiocytic sarcoma. These tumors have variable biologic behavior, although the malignant disorders often have a poor prognosis. Immunohistochemistry plays an essential role in differentiating histiocytic tumors from other neoplasias that may have similar histological appearances. This allows a definitive diagnosis to be established and provides a more accurate prediction of prognosis. This article reviews the biologic behavior, diagnosis, and treatment of histiocytic tumors in the dog. (+info)Pulmonary features of Birt-Hogg-Dube syndrome: cystic lesions and pulmonary histiocytoma. (8/10)
(+info)Benign fibrous histiocytoma (BFH) is a common benign tumor of the skin and superficial soft tissues. It primarily affects middle-aged adults and is more prevalent in men than women. The exact cause of BFH is unknown, but it's thought to arise from dermal fibroblasts or histiocytes.
Medical Definition: Benign Fibrous Histiocytoma (BFH) is a benign, slowly growing, solitary cutaneous or subcutaneous nodular tumor predominantly composed of a mixture of fibroblastic and histiocytic-like cells. The tumor typically presents as a well-circumscribed, firm, dome-shaped papule or nodule, ranging in size from a few millimeters to several centimeters. Histologically, BFH is characterized by the proliferation of spindle-shaped fibroblasts and histiocytes arranged in a storiform pattern, along with variable amounts of collagen deposition, multinucleated giant cells, and hemosiderin deposits. The lesion usually has a pushing border with no invasion into the surrounding tissues. BFH generally follows a benign clinical course, with local recurrence being uncommon following complete surgical excision.
Malignant fibrous histiocytoma (MFH) is not a specific type of histiocytoma; rather, it is a type of soft tissue sarcoma. Histiocytomas are benign tumors that arise from cells called histiocytes, which are part of the immune system. MFH, on the other hand, is a malignant (cancerous) tumor that can arise in various types of soft tissues, such as muscle, fat, tendons, and ligaments.
MFH was once thought to originate from histiocytes, but more recent research suggests that it may actually arise from undifferentiated mesenchymal cells, which are capable of developing into a variety of different cell types. MFH is the most common type of soft tissue sarcoma in adults over the age of 50 and typically presents as a painless mass in the extremities or retroperitoneum (the area in the back of the abdomen).
The tumor is characterized by the presence of fibroblastic and histiocytic-like cells, which can be quite pleomorphic (varied in shape and size) and may contain numerous mitotic figures (indicating rapid cell division). Treatment typically involves surgical excision, often followed by radiation therapy and/or chemotherapy. The prognosis for MFH depends on several factors, including the tumor's location, size, grade (degree of differentiation), and the patient's age and overall health.
Histiocytoma is a general term used to describe a group of disorders characterized by an abnormal accumulation or proliferation of histiocytes, which are a type of immune cell. These cells normally play a role in fighting infection and helping to heal wounds. However, when they multiply excessively, they can form tumors known as histiocytomas.
There are several types of histiocytomas, including:
1. Cutaneous histiocytoma: This is the most common type of histiocytoma, which typically appears as a small, raised, hairless, and pink or red bump on the skin. It usually affects dogs, but can also occur in cats and rarely in humans. These tumors are benign and often regress spontaneously within a few months.
2. Systemic histiocytoses: These are less common types of histiocytomas that involve multiple organs and tissues throughout the body. They can be further classified into several subtypes, such as Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and malignant histiocytosis. These conditions can range from benign to malignant and may require aggressive treatment, including chemotherapy or radiation therapy.
It is important to note that while histiocytomas are generally benign, they can sometimes mimic other more serious conditions. Therefore, it is essential to have any suspicious growths evaluated by a veterinarian or healthcare professional for proper diagnosis and management.
Soft tissue neoplasms refer to abnormal growths or tumors that develop in the soft tissues of the body. Soft tissues include muscles, tendons, ligaments, fascia, nerves, blood vessels, fat, and synovial membranes (the thin layer of cells that line joints and tendons). Neoplasms can be benign (non-cancerous) or malignant (cancerous), and their behavior and potential for spread depend on the specific type of neoplasm.
Benign soft tissue neoplasms are typically slow-growing, well-circumscribed, and rarely spread to other parts of the body. They can often be removed surgically with a low risk of recurrence. Examples of benign soft tissue neoplasms include lipomas (fat tumors), schwannomas (nerve sheath tumors), and hemangiomas (blood vessel tumors).
Malignant soft tissue neoplasms, on the other hand, can grow rapidly, invade surrounding tissues, and may metastasize (spread) to distant parts of the body. They are often more difficult to treat than benign neoplasms and require a multidisciplinary approach, including surgery, radiation therapy, and chemotherapy. Examples of malignant soft tissue neoplasms include sarcomas, such as rhabdomyosarcoma (arising from skeletal muscle), leiomyosarcoma (arising from smooth muscle), and angiosarcoma (arising from blood vessels).
It is important to note that soft tissue neoplasms can occur in any part of the body, and their diagnosis and treatment require a thorough evaluation by a healthcare professional with expertise in this area.
Histiocytic sarcoma is a rare type of cancer that originates from histiocytes, which are cells that are part of the immune system and found in various tissues throughout the body. These cells normally function to help fight infection and remove foreign substances. In histiocytic sarcoma, there is an abnormal accumulation and proliferation of these cells, leading to the formation of tumors.
Histiocytic sarcoma can affect people of any age but is more commonly found in adults, with a slight male predominance. It can occur in various parts of the body, such as the lymph nodes, skin, soft tissues, and internal organs like the spleen, liver, and lungs. The exact cause of histiocytic sarcoma remains unknown, but it is not considered to be hereditary.
The symptoms of histiocytic sarcoma depend on the location and extent of the tumor(s). Common signs include swollen lymph nodes, fatigue, fever, weight loss, night sweats, and pain or discomfort in the affected area. Diagnosis typically involves a combination of imaging studies (like CT scans, PET scans, or MRI), biopsies, and laboratory tests to confirm the presence of histiocytic sarcoma and assess its extent.
Treatment for histiocytic sarcoma usually involves a multidisciplinary approach, including surgery, radiation therapy, and chemotherapy. The choice of treatment depends on several factors, such as the location and stage of the disease, the patient's overall health, and their personal preferences. Clinical trials may also be an option for some patients, allowing them to access new and experimental therapies.
Prognosis for histiocytic sarcoma is generally poor, with a five-year survival rate of approximately 15-30%. However, outcomes can vary significantly depending on individual factors, such as the patient's age, the extent of the disease at diagnosis, and the effectiveness of treatment. Continued research is necessary to improve our understanding of this rare cancer and develop more effective therapies for those affected.
Sarcoma is a type of cancer that develops from certain types of connective tissue (such as muscle, fat, fibrous tissue, blood vessels, or nerves) found throughout the body. It can occur in any part of the body, but it most commonly occurs in the arms, legs, chest, and abdomen.
Sarcomas are classified into two main groups: bone sarcomas and soft tissue sarcomas. Bone sarcomas develop in the bones, while soft tissue sarcomas develop in the soft tissues of the body, such as muscles, tendons, ligaments, fat, blood vessels, and nerves.
Sarcomas can be further classified into many subtypes based on their specific characteristics, such as the type of tissue they originate from, their genetic makeup, and their appearance under a microscope. The different subtypes of sarcoma have varying symptoms, prognoses, and treatment options.
Overall, sarcomas are relatively rare cancers, accounting for less than 1% of all cancer diagnoses in the United States each year. However, they can be aggressive and may require intensive treatment, such as surgery, radiation therapy, and chemotherapy.
Skull neoplasms refer to abnormal growths or tumors that develop within the skull. These growths can be benign (non-cancerous) or malignant (cancerous). They can originate from various types of cells, such as bone cells, nerve cells, or soft tissues. Skull neoplasms can cause various symptoms depending on their size and location, including headaches, seizures, vision problems, hearing loss, and neurological deficits. Treatment options include surgery, radiation therapy, and chemotherapy. It is important to note that a neoplasm in the skull can also refer to metastatic cancer, which has spread from another part of the body to the skull.
Liposarcoma is a type of soft tissue sarcoma, which is a cancer that develops in the soft tissues of the body, such as fat, muscle, nerves, blood vessels, and fibrous tissues. Specifically, liposarcoma arises from fat cells (adipocytes) or their precursors.
There are several subtypes of liposarcoma, which differ in their appearance under the microscope, genetic features, and clinical behavior. These include well-differentiated, dedifferentiated, myxoid, round cell, and pleomorphic liposarcomas. The most common sites for liposarcoma are the thigh, retroperitoneum (the area behind the abdominal cavity), and the buttock.
Liposarcomas can grow slowly or rapidly, and they may spread to other parts of the body (metastasize) through the bloodstream or lymphatic system. Treatment typically involves surgical removal of the tumor, often followed by radiation therapy and/or chemotherapy. The prognosis for liposarcoma depends on several factors, including the type and grade of the tumor, its size and location, and whether it has spread to other parts of the body.
Retroperitoneal neoplasms refer to abnormal growths or tumors that develop in the retroperitoneal space. This is the area located behind the peritoneum, which is the membrane that lines the abdominal cavity and covers the abdominal organs. The retroperitoneal space contains several vital structures such as the kidneys, adrenal glands, pancreas, aorta, and lymphatic vessels.
Retroperitoneal neoplasms can be benign or malignant (cancerous). Malignant retroperitoneal neoplasms are often aggressive and can invade surrounding tissues and organs, leading to various complications. Common types of retroperitoneal neoplasms include lymphomas, sarcomas, and metastatic tumors from other primary sites. Symptoms may vary depending on the size and location of the tumor but can include abdominal or back pain, weight loss, and swelling in the legs. Diagnosis typically involves imaging studies such as CT scans or MRI, followed by a biopsy to determine the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Femoral neoplasms refer to abnormal growths or tumors that develop in the femur, which is the long thigh bone in the human body. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Benign femoral neoplasms are slow-growing and rarely spread to other parts of the body, while malignant neoplasms are aggressive and can invade nearby tissues and organs, as well as metastasize (spread) to distant sites.
There are various types of femoral neoplasms, including osteochondromas, enchondromas, chondrosarcomas, osteosarcomas, and Ewing sarcomas, among others. The specific type of neoplasm is determined by the cell type from which it arises and its behavior.
Symptoms of femoral neoplasms may include pain, swelling, stiffness, or weakness in the thigh, as well as a palpable mass or limited mobility. Diagnosis typically involves imaging studies such as X-rays, CT scans, or MRI, as well as biopsy to determine the type and grade of the tumor. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches, depending on the type, size, location, and stage of the neoplasm.
Angiomatosis is a medical term that refers to a benign condition characterized by the proliferation of blood vessels in various tissues and organs. It is typically composed of small, tangled blood vessels called capillaries, which can form clusters or networks. The condition can affect skin, internal organs, bones, and other tissues.
Angiomatosis is often asymptomatic and may be discovered incidentally during medical imaging or surgical procedures. In some cases, it may cause symptoms such as pain, swelling, or bleeding, depending on the location and extent of the lesions.
While angiomatosis is generally a benign condition, in rare cases, it can be associated with malignant tumors or other medical conditions. Treatment options for angiomatosis depend on the size, location, and symptoms of the lesions and may include observation, medication, or surgical removal.
Myxosarcoma is a very rare type of soft tissue sarcoma, a cancer that develops in the soft tissues of the body, such as fat, muscle, nerves, blood vessels, and fibrous tissues. Myxosarcomas are characterized by the presence of mucoid or gelatinous material in the tumor, which is composed of an abnormal accumulation of acid mucopolysaccharides. These tumors typically affect adults, with a peak incidence in the sixth to seventh decade of life. They usually occur in the extremities, particularly the lower limbs, and can also arise in the retroperitoneum or other deep soft tissues. Myxosarcomas are classified into several subtypes based on their histological features, with the most common being the myxofibrosarcoma. Treatment typically involves surgical resection with wide margins, often followed by radiation therapy and/or chemotherapy. The prognosis for patients with myxosarcoma depends on several factors, including the size and location of the tumor, the histological grade, and the patient's age and overall health.
Piezosurgery is a type of surgical procedure that uses ultrasonic vibrations to cut through bone tissue while minimizing damage to surrounding soft tissues. It is often used in oral and maxillofacial surgery, such as during dental implant placement or jaw osteotomies. The piezoelectric instrument generates high-frequency microvibrations that selectively cut mineralized tissue like bone, while leaving adjacent soft tissues largely unaffected. This allows for precise cuts with less trauma and bleeding compared to traditional surgical techniques, potentially resulting in faster healing times and reduced postoperative discomfort.
Vascular neoplasms are a type of tumor that develops from cells that line the blood vessels or lymphatic vessels. These tumors can be benign (non-cancerous) or malignant (cancerous). Benign vascular neoplasms, such as hemangiomas and lymphangiomas, are usually harmless and may not require treatment unless they cause symptoms or complications. Malignant vascular neoplasms, on the other hand, are known as angiosarcomas and can be aggressive, spreading to other parts of the body and potentially causing serious health problems.
Angiosarcomas can develop in any part of the body but are most commonly found in the skin, particularly in areas exposed to radiation or chronic lymph edema. They can also occur in the breast, liver, spleen, and heart. Treatment for vascular neoplasms depends on the type, location, size, and stage of the tumor, as well as the patient's overall health. Treatment options may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Heart neoplasms are abnormal growths or tumors that develop within the heart tissue. They can be benign (noncancerous) or malignant (cancerous). Benign tumors, such as myxomas and rhabdomyomas, are typically slower growing and less likely to spread, but they can still cause serious complications if they obstruct blood flow or damage heart valves. Malignant tumors, such as angiosarcomas and rhabdomyosarcomas, are fast-growing and have a higher risk of spreading to other parts of the body. Symptoms of heart neoplasms can include shortness of breath, chest pain, fatigue, and irregular heart rhythms. Treatment options depend on the type, size, and location of the tumor, and may include surgery, radiation therapy, or chemotherapy.
Bone neoplasms are abnormal growths or tumors that develop in the bone. They can be benign (non-cancerous) or malignant (cancerous). Benign bone neoplasms do not spread to other parts of the body and are rarely a threat to life, although they may cause problems if they grow large enough to press on surrounding tissues or cause fractures. Malignant bone neoplasms, on the other hand, can invade and destroy nearby tissue and may spread (metastasize) to other parts of the body.
There are many different types of bone neoplasms, including:
1. Osteochondroma - a benign tumor that develops from cartilage and bone
2. Enchondroma - a benign tumor that forms in the cartilage that lines the inside of the bones
3. Chondrosarcoma - a malignant tumor that develops from cartilage
4. Osteosarcoma - a malignant tumor that develops from bone cells
5. Ewing sarcoma - a malignant tumor that develops in the bones or soft tissues around the bones
6. Giant cell tumor of bone - a benign or occasionally malignant tumor that develops from bone tissue
7. Fibrosarcoma - a malignant tumor that develops from fibrous tissue in the bone
The symptoms of bone neoplasms vary depending on the type, size, and location of the tumor. They may include pain, swelling, stiffness, fractures, or limited mobility. Treatment options depend on the type and stage of the tumor but may include surgery, radiation therapy, chemotherapy, or a combination of these treatments.
Genital neoplasms in males refer to abnormal growths or tumors that develop in the male reproductive organs. These can be benign (non-cancerous) or malignant (cancerous).
Malignant genital neoplasms are often referred to as genital cancers. The most common types of male genital cancers include:
1. Penile Cancer: This occurs when cancer cells form in the tissues of the penis.
2. Testicular Cancer: This forms in the testicles (testes), which are located inside the scrotum.
3. Prostate Cancer: This is a common cancer in men, forming in the prostate gland, which is part of the male reproductive system that helps make semen.
4. Scrotal Cancer: This is a rare form of cancer that forms in the skin or tissue of the scrotum.
5. Penile Intraepithelial Neoplasia (PeIN): This is not cancer, but it is considered a pre-cancerous condition of the penis.
Early detection and treatment of genital neoplasms can significantly improve the prognosis. Regular self-examinations and medical check-ups are recommended, especially for individuals with risk factors such as smoking, HIV infection, or a family history of these cancers.
Tracheobronchomegaly is a rare condition characterized by an abnormal dilatation or widening of the trachea and bronchi, which are the airway tubes leading to the lungs. This condition is also known as Mounier-Kuhn syndrome. It is typically associated with recurrent respiratory infections, coughing, and difficulty breathing, especially during physical exertion. The exact cause of tracheobronchomegaly is not well understood, but it may be related to a congenital abnormality or connective tissue disorder. Diagnosis is often made through imaging studies such as chest X-rays or CT scans. Treatment typically involves managing symptoms and preventing complications, and may include bronchodilators, antibiotics, and respiratory therapy. In severe cases, surgery may be necessary to repair or reinforce the airway walls.
A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.
There is no medical definition for "dog diseases" as it is too broad a term. However, dogs can suffer from various health conditions and illnesses that are specific to their species or similar to those found in humans. Some common categories of dog diseases include:
1. Infectious Diseases: These are caused by viruses, bacteria, fungi, or parasites. Examples include distemper, parvovirus, kennel cough, Lyme disease, and heartworms.
2. Hereditary/Genetic Disorders: Some dogs may inherit certain genetic disorders from their parents. Examples include hip dysplasia, elbow dysplasia, progressive retinal atrophy (PRA), and degenerative myelopathy.
3. Age-Related Diseases: As dogs age, they become more susceptible to various health issues. Common age-related diseases in dogs include arthritis, dental disease, cancer, and cognitive dysfunction syndrome (CDS).
4. Nutritional Disorders: Malnutrition or improper feeding can lead to various health problems in dogs. Examples include obesity, malnutrition, and vitamin deficiencies.
5. Environmental Diseases: These are caused by exposure to environmental factors such as toxins, allergens, or extreme temperatures. Examples include heatstroke, frostbite, and toxicities from ingesting harmful substances.
6. Neurological Disorders: Dogs can suffer from various neurological conditions that affect their nervous system. Examples include epilepsy, intervertebral disc disease (IVDD), and vestibular disease.
7. Behavioral Disorders: Some dogs may develop behavioral issues due to various factors such as anxiety, fear, or aggression. Examples include separation anxiety, noise phobias, and resource guarding.
It's important to note that regular veterinary care, proper nutrition, exercise, and preventative measures can help reduce the risk of many dog diseases.
Spontaneous neoplasm regression is a rare and somewhat controversial phenomenon in which a tumor or malignancy appears to decrease in size or disappear without any treatment or with treatment that is typically not expected to produce such an effect. This can occur through various mechanisms, including immune-mediated processes, apoptosis (programmed cell death), differentiation of cancer cells into normal cells, and angiogenesis inhibition (preventing the growth of new blood vessels that feed the tumor).
Spontaneous regression of neoplasms is not well understood and is considered unpredictable. It has been reported in various types of cancers, including neuroblastoma, melanoma, renal cell carcinoma, and others. However, it should be noted that spontaneous regression does not imply a cure, as the tumor may still recur or metastasize later on.
In summary, spontaneous neoplasm regression refers to the partial or complete disappearance of a malignancy without any specific treatment or with treatment that is not typically associated with such an effect.
In the context of human anatomy, the thigh is the part of the lower limb that extends from the hip to the knee. It is the upper and largest portion of the leg and is primarily composed of the femur bone, which is the longest and strongest bone in the human body, as well as several muscles including the quadriceps femoris (front thigh), hamstrings (back thigh), and adductors (inner thigh). The major blood vessels and nerves that supply the lower limb also pass through the thigh.
Giant cell tumors (GCTs) are a type of benign or rarely malignant bone tumor that is characterized by the presence of multinucleated giant cells. These tumors typically affect adults between the ages of 20 and 40, and they can occur in any bone, but they most commonly involve the long bones near the knee joint.
GCTs are composed of three types of cells: mononuclear stromal cells, which produce the matrix of the tumor; multinucleated osteoclast-like giant cells, which resemble the bone-resorbing cells found in normal bone; and macrophages, which are part of the body's immune system.
The mononuclear stromal cells produce a variety of growth factors that stimulate the formation and activity of the osteoclast-like giant cells, leading to localized bone destruction. The tumor may cause pain, swelling, and limited mobility in the affected area.
While GCTs are typically benign, they can be aggressive and locally destructive, with a tendency to recur after surgical removal. In some cases, GCTs may undergo malignant transformation, leading to the development of sarcomas. Treatment options for GCTs include curettage (scraping out) of the tumor, followed by bone grafting or the use of a cement spacer to fill the defect, and/or adjuvant therapy with radiation or chemotherapy.
A fibroma is a benign (non-cancerous) tumor that consists primarily of fibrous or connective tissue. It can occur in various parts of the body, including the skin, mouth, and internal organs. The term "fibroma" is often used to describe any benign fibrous growth, but there are specific types of fibromas such as dermatofibroma (found in the skin), oral fibroma (found in the mouth), and benign fibrous histiocytoma (found in soft tissues).
It's important to note that while fibromas are generally harmless, they can cause discomfort or problems depending on their size and location. If a fibroma is causing issues or there's concern about its growth or malignancy, it should be evaluated by a healthcare professional for potential removal or further assessment.
Histiocytes are a type of immune cell that are part of the mononuclear phagocyte system. They originate from monocytes, which are derived from hematopoietic stem cells in the bone marrow. Histiocytes play an important role in the immune system by engulfing and destroying foreign substances, such as bacteria and viruses, as well as removing dead cells and other debris from the body. They can be found in various tissues throughout the body, including the skin, lymph nodes, spleen, and liver.
Histiocytes include several different types of cells, such as macrophages, dendritic cells, and Langerhans cells. These cells have different functions but all play a role in the immune response. For example, macrophages are involved in inflammation and tissue repair, while dendritic cells are important for presenting antigens to T cells and initiating an immune response.
Abnormal accumulations or dysfunction of histiocytes can lead to various diseases, such as histiocytosis, which is a group of disorders characterized by the abnormal proliferation and accumulation of histiocytes in various tissues.
Maxillary sinus neoplasms refer to abnormal growths or tumors that develop in the maxillary sinuses, which are located in the upper part of your cheekbones, below your eyes. These growths can be benign (non-cancerous) or malignant (cancerous).
Benign neoplasms may include conditions such as an osteoma (a benign bone tumor), a papilloma (a benign growth of the lining of the sinus), or a fibrous dysplasia (a condition where bone is replaced by fibrous tissue).
Malignant neoplasms, on the other hand, can be primary (originating in the maxillary sinuses) or secondary (spreading to the maxillary sinuses from another site in the body). Common types of malignant tumors that arise in the maxillary sinus include squamous cell carcinoma, adenocarcinoma, and mucoepidermoid carcinoma.
Symptoms of maxillary sinus neoplasms may include nasal congestion, nosebleeds, facial pain or numbness, vision changes, and difficulty swallowing or speaking. Treatment options depend on the type, size, and location of the tumor but may include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Immunohistochemistry (IHC) is a technique used in pathology and laboratory medicine to identify specific proteins or antigens in tissue sections. It combines the principles of immunology and histology to detect the presence and location of these target molecules within cells and tissues. This technique utilizes antibodies that are specific to the protein or antigen of interest, which are then tagged with a detection system such as a chromogen or fluorophore. The stained tissue sections can be examined under a microscope, allowing for the visualization and analysis of the distribution and expression patterns of the target molecule in the context of the tissue architecture. Immunohistochemistry is widely used in diagnostic pathology to help identify various diseases, including cancer, infectious diseases, and immune-mediated disorders.
Orbital neoplasms refer to abnormal growths or tumors that develop in the orbit, which is the bony cavity that contains the eyeball, muscles, nerves, fat, and blood vessels. These neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from various types of cells within the orbit.
Orbital neoplasms can cause a variety of symptoms depending on their size, location, and rate of growth. Common symptoms include protrusion or displacement of the eyeball, double vision, limited eye movement, pain, swelling, and numbness in the face. In some cases, orbital neoplasms may not cause any noticeable symptoms, especially if they are small and slow-growing.
There are many different types of orbital neoplasms, including:
1. Optic nerve glioma: a rare tumor that arises from the optic nerve's supportive tissue.
2. Orbital meningioma: a tumor that originates from the membranes covering the brain and extends into the orbit.
3. Lacrimal gland tumors: benign or malignant growths that develop in the lacrimal gland, which produces tears.
4. Orbital lymphangioma: a non-cancerous tumor that arises from the lymphatic vessels in the orbit.
5. Rhabdomyosarcoma: a malignant tumor that develops from the skeletal muscle cells in the orbit.
6. Metastatic tumors: cancerous growths that spread to the orbit from other parts of the body, such as the breast, lung, or prostate.
The diagnosis and treatment of orbital neoplasms depend on several factors, including the type, size, location, and extent of the tumor. Imaging tests, such as CT scans and MRI, are often used to visualize the tumor and determine its extent. A biopsy may also be performed to confirm the diagnosis and determine the tumor's type and grade. Treatment options include surgery, radiation therapy, chemotherapy, or a combination of these approaches.
Skin neoplasms refer to abnormal growths or tumors in the skin that can be benign (non-cancerous) or malignant (cancerous). They result from uncontrolled multiplication of skin cells, which can form various types of lesions. These growths may appear as lumps, bumps, sores, patches, or discolored areas on the skin.
Benign skin neoplasms include conditions such as moles, warts, and seborrheic keratoses, while malignant skin neoplasms are primarily classified into melanoma, squamous cell carcinoma, and basal cell carcinoma. These three types of cancerous skin growths are collectively known as non-melanoma skin cancers (NMSCs). Melanoma is the most aggressive and dangerous form of skin cancer, while NMSCs tend to be less invasive but more common.
It's essential to monitor any changes in existing skin lesions or the appearance of new growths and consult a healthcare professional for proper evaluation and treatment if needed.
Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer that begins in the middle layer of the skin known as the dermis. It often appears as a scar or bruise that does not go away and may grow slowly over time, sometimes spreading to deeper tissues and other parts of the body. DFSP can be difficult to treat if it has spread, but when caught early, it is usually curable with surgery.
DFSP is characterized by the growth of abnormal fibroblasts, which are cells that produce collagen, a protein that helps make up connective tissues in the body. The exact cause of DFSP is not known, but it has been linked to genetic mutations and previous injuries or surgeries to the skin.
Treatment for DFSP typically involves surgical removal of the tumor, along with a margin of healthy tissue around it. In some cases, radiation therapy or targeted therapy may also be used to help ensure that all cancer cells have been removed. Regular follow-up care is important to monitor for any signs of recurrence or spread of the disease.
X-ray computed tomography (CT or CAT scan) is a medical imaging method that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional (tomographic) images (virtual "slices") of the body. These cross-sectional images can then be used to display detailed internal views of organs, bones, and soft tissues in the body.
The term "computed tomography" is used instead of "CT scan" or "CAT scan" because the machines take a series of X-ray measurements from different angles around the body and then use a computer to process these data to create detailed images of internal structures within the body.
CT scanning is a noninvasive, painless medical test that helps physicians diagnose and treat medical conditions. CT imaging provides detailed information about many types of tissue including lung, bone, soft tissue and blood vessels. CT examinations can be performed on every part of the body for a variety of reasons including diagnosis, surgical planning, and monitoring of therapeutic responses.
In computed tomography (CT), an X-ray source and detector rotate around the patient, measuring the X-ray attenuation at many different angles. A computer uses this data to construct a cross-sectional image by the process of reconstruction. This technique is called "tomography". The term "computed" refers to the use of a computer to reconstruct the images.
CT has become an important tool in medical imaging and diagnosis, allowing radiologists and other physicians to view detailed internal images of the body. It can help identify many different medical conditions including cancer, heart disease, lung nodules, liver tumors, and internal injuries from trauma. CT is also commonly used for guiding biopsies and other minimally invasive procedures.
In summary, X-ray computed tomography (CT or CAT scan) is a medical imaging technique that uses computer-processed combinations of many X-ray images taken from different angles to produce cross-sectional images of the body. It provides detailed internal views of organs, bones, and soft tissues in the body, allowing physicians to diagnose and treat medical conditions.
Osteosarcoma is defined as a type of cancerous tumor that arises from the cells that form bones (osteoblasts). It's the most common primary bone cancer, and it typically develops in the long bones of the body, such as the arms or legs, near the growth plates. Osteosarcoma can metastasize (spread) to other parts of the body, including the lungs, making it a highly malignant form of cancer. Symptoms may include bone pain, swelling, and fractures. Treatment usually involves a combination of surgery, chemotherapy, and/or radiation therapy.
Cystadenocarcinoma is a type of tumor that arises from the epithelial lining of a cyst, and it has the potential to invade surrounding tissues and spread (metastasize) to other parts of the body. It typically affects glandular organs such as the ovaries, pancreas, and salivary glands.
Cystadenocarcinomas can be classified into two types: serous and mucinous. Serous cystadenocarcinomas produce a watery fluid, while mucinous cystadenocarcinomas produce a thick, mucus-like fluid. Both types of tumors can be benign or malignant, but malignant cystadenocarcinomas are more aggressive and have a higher risk of metastasis.
Symptoms of cystadenocarcinoma depend on the location and size of the tumor. In some cases, there may be no symptoms until the tumor has grown large enough to cause pain or other problems. Treatment typically involves surgical removal of the tumor, along with any affected surrounding tissue. Chemotherapy and radiation therapy may also be used in some cases to help prevent recurrence or spread of the cancer.
Leiomyosarcoma is a type of cancer that arises from the smooth muscle cells, which are responsible for the involuntary contractions of various organs and blood vessels. It most commonly occurs in the uterus, soft tissues (such as muscles and fat), and the gastrointestinal tract.
Leiomyosarcomas can vary in their aggressiveness and may spread to other parts of the body (metastasize) through the bloodstream or lymphatic system. The prognosis for leiomyosarcoma depends on several factors, including the location and size of the tumor, the patient's age and overall health, and the extent of metastasis. Treatment typically involves surgical removal of the tumor, along with radiation therapy and/or chemotherapy to help prevent recurrence or spread of the cancer.
Multiple primary neoplasms refer to the occurrence of more than one primary malignant tumor in an individual, where each tumor is unrelated to the other and originates from separate cells or organs. This differs from metastatic cancer, where a single malignancy spreads to multiple sites in the body. Multiple primary neoplasms can be synchronous (occurring at the same time) or metachronous (occurring at different times). The risk of developing multiple primary neoplasms increases with age and is associated with certain genetic predispositions, environmental factors, and lifestyle choices such as smoking and alcohol consumption.
Chondrosarcoma is a type of cancer that develops in the cartilaginous tissue, which is the flexible and smooth connective tissue found in various parts of the body such as the bones, ribs, and nose. It is characterized by the production of malignant cartilage cells that can invade surrounding tissues and spread to other parts of the body (metastasis).
Chondrosarcomas are typically slow-growing tumors but can be aggressive in some cases. They usually occur in adults over the age of 40, and men are more commonly affected than women. The most common sites for chondrosarcoma development include the bones of the pelvis, legs, and arms.
Treatment for chondrosarcoma typically involves surgical removal of the tumor, along with radiation therapy or chemotherapy in some cases. The prognosis for chondrosarcoma depends on several factors, including the size and location of the tumor, the grade of malignancy, and whether it has spread to other parts of the body.
Mediastinal neoplasms refer to abnormal growths or tumors located in the mediastinum, which is the central compartment of the thoracic cavity that lies between the lungs and contains various vital structures such as the heart, esophagus, trachea, blood vessels, lymph nodes, and nerves. Mediastinal neoplasms can be benign (non-cancerous) or malignant (cancerous), and they can arise from any of the tissues or organs within the mediastinum.
Benign mediastinal neoplasms may include thymomas, lipomas, neurofibromas, or teratomas, among others. These tumors are typically slow-growing and rarely spread to other parts of the body. However, they can still cause symptoms or complications by compressing adjacent structures within the mediastinum, such as the airways, blood vessels, or nerves.
Malignant mediastinal neoplasms are cancerous tumors that can invade and destroy surrounding tissues and may spread (metastasize) to other parts of the body. Common types of malignant mediastinal neoplasms include thymic carcinomas, lymphomas, germ cell tumors, and neuroendocrine tumors. These tumors often require aggressive treatment, such as surgery, radiation therapy, and chemotherapy, to control their growth and spread.
It is important to note that mediastinal neoplasms can present with various symptoms depending on their location, size, and type. Some patients may be asymptomatic, while others may experience cough, chest pain, difficulty breathing, hoarseness, or swallowing difficulties. A thorough diagnostic workup, including imaging studies and biopsies, is necessary to confirm the diagnosis and determine the best course of treatment for mediastinal neoplasms.
Histiocytoma
Histiocytoma (dog)
Angiomatoid fibrous histiocytoma
Epithelioid cell histiocytoma
Progressive nodular histiocytoma
Generalized eruptive histiocytoma
Sarcoma
List of OMIM disorder codes
Xanthogranulomatous inflammation
Sharon Weiss
Averill A. Liebow
Hardcastle syndrome
Margaret Ransone Murray
Vaccine-associated sarcoma
Atypical fibroxanthoma
List of dog diseases
Canine histiocytic diseases
Fibrosarcoma
Fibroblastic and myofibroblastic tumors
Doege-Potter syndrome
Betacellulin
Epiregulin
Low-grade myofibroblastic sarcoma
FET protein family
Ectomesenchymoma
Myxofibrosarcoma
Nodular fasciitis
Ewing sarcoma
Kaposi's sarcoma
Liposarcoma
Histiocytoma - Wikipedia
Histiocytoma In Dogs: Causes, Symptoms, Treatment & Costs
Histiocytoma in Dogs: Symptoms, Causes, Treatment, and FAQs | PetMD
Pleomorphic Sarcoma (Malignant Fibrous Histiocytoma) of Soft Tissue Imaging: Practice Essentials, Radiography, Computed...
Atypical Fibrous Histiocytoma of the Skin: Clinicopathologic... : The American Journal of Surgical Pathology
Mfhas1 MGI Mouse Gene Detail - MGI:1098644 - malignant fibrous histiocytoma amplified sequence 1
Malignant Fibrous Histiocytoma Global Clinical Trials Review, H2, 2016
Histiocytoma - Mar Vista Animal Medical Center
Development of Chronic Myelocytic Leukemia after Chemotherapy for Malignant Fibrous Histiocytoma | Acta Haematologica | Karger...
Recurrent aneurysmal fibrous histiocytoma | Journal of Clinical Pathology
What Is Malignant Fibrous Histiocytoma? Symptoms & Treatment - Hdkino.org
Malignant fibrous histiocytoma - causes, side effects and treatments at NaturalPedia.com
Benign fibrous histiocytoma of submandibular space | Abstract
Primary pulmonary synovial sarcoma diagnosed ten years after treatment for malignant fibrous histiocytoma
Benign fibrous histiocytoma in hodgkin's disease<...
Malignant fibrous histiocytoma
Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker) - Clone SERPINA3/4187 | 12
Myxoid malignant fibrous histiocytoma of the bladder<...
Malignant Fibrous Histiocytoma (Skin) - Symptoms, Treatment & Support - Without a Ribbon
Mitosis and apoptosis in canine cutaneous histiocytoma and transmissible venereal tumour | AVESÄ°S
A case of intracranial malignant fibrous histiocytoma | Sarrami | Journal of Research in Medical Sciences
Coexistance of Angiomatoid Fibrous Histiocytoma and Familial Mediterranean Fever (FMF): A Case Report | AVESÄ°S
Castor Oil for Dogs and Cats
Treatment of Malignant Fibrous Histiocytoma and Atypical Fibrous Xanthomas with Micrographic Surgery<...
British Medical Journal: 298 (6675) | The BMJ
Tuft SJ[au] - Search Results - PubMed
A new complication of retained surgical gauze: development of malignant fibrous histiocytoma - report of a case with a...
Late development of a malignant fibrous histiocytoma at the site of a giant cell tumor<...
Malignant34
- malignant fibrous histiocytoma: This tumor is now termed undifferentiated pleomorphic sarcoma (UPS) because more recently developed immunohistochemistry and cytogenetic analyses suggest that its neoplastic cells most likely arise from mesenchymal stem cells or fibroblasts rather than histiocytes. (wikipedia.org)
- Undifferentiated pleomorphic sarcoma (UPS), previously called malignant fibrous histiocytoma (MFH), is a soft tissue sarcoma (STS) that can occur anywhere in the body, but it usually occurs in the extremities (especially the thighs) or back of the abdomen (see the image below). (medscape.com)
- The malignant fibrous histiocytoma is only slightly hypodense to muscle and conceivably could be overlooked. (medscape.com)
- Historically, the term malignant fibrous histiocytoma (MFH) was applied to pleomorphic spindle cell neoplasms with fibroblastic and histiocytic differentiation. (medscape.com)
- The histiocytoma is not related to the malignant process called "histiocytosis. (marvistavet.com)
- GlobalData's clinical trial report, "Malignant Fibrous Histiocytoma Global Clinical Trials Review, H2, 2016' provides an overview of Malignant Fibrous Histiocytoma clinical trials scenario. (globaldata.com)
- This report provides top line data relating to the clinical trials on Malignant Fibrous Histiocytoma. (globaldata.com)
- At the age of 28, a 33-year-old male was diagnosed with malignant fibrous histiocytoma (MFH) with a primary lesion in the right maxillary sinus. (karger.com)
- A malignant fibrous histiocytoma (MFH) is a type of soft tissue sarcoma (malignant tumor). (naturalpedia.com)
- Home Uncategorized What Is Malignant Fibrous Histiocytoma? (hdkino.org)
- Also called pleomorphic undifferentiated sarcoma, malignant fibrous histiocytoma usually occurs in the legs, arms, or abdomen. (hdkino.org)
- The exact cause of malignant fibrous histiocytoma is still unknown, although research is underway to find more about the condition. (hdkino.org)
- What are the symptoms of malignant fibrous histiocytoma? (hdkino.org)
- Malignant fibrous histiocytoma replaces healthy bone tissue with cancer cells. (hdkino.org)
- How is malignant fibrous histiocytoma diagnosed? (hdkino.org)
- How is malignant fibrous histiocytoma treated? (hdkino.org)
- Surgery to remove the tumor is the first line of treatment for malignant histiocytoma. (hdkino.org)
- The most important diagnostic distinction is the separation of this tumor from aggressive forms of fibrohistiocytic neoplasms like dermatofibrosarcoma protuberans and malignant fibrous histiocytoma. (alliedacademies.org)
- What is Malignant Fibrous Histiocytoma of the Skin? (withoutaribbon.org)
- Malignant fibrous histiocytoma of the skin is a rare type of soft tissue cancer but may also develop in the bones. (withoutaribbon.org)
- There is no well-known cause however certain hereditary and genetic mutations along with the history of radiotherapy are the important contributing risk factors for the development of malignant fibrous histiocytoma. (withoutaribbon.org)
- What Support can we Give for Malignant Fibrous Histiocytoma? (withoutaribbon.org)
- Malignant Fibrous Histiocytoma is rare cancer, meaning it is not as well known as other forms of cancer. (withoutaribbon.org)
- If you suffer from rare cancer such as Malignant Fibrous Histiocytoma, we can help and support you through your journey thanks to the generous donations we receive. (withoutaribbon.org)
- Although the most common soft tissue sarcoma of adulthood, malignant fibrous histiocytoma (MFH) is an extremely rare tumor of the urinary bladder. (johnshopkins.edu)
- Brendler, Charles B. / Myxoid malignant fibrous histiocytoma of the bladder . (johnshopkins.edu)
- We describe a case of intracranial malignant fibrous histiocytoma which had infiltrated pons, cerebellum and basal surface of left temporal lobe without any visible mass. (ac.ir)
- In the autopsy, histological and immunohistochemical study of the brain revealed the diagnosis of malignant fibrous histiocytoma (MFH). (ac.ir)
- BROWN, MARCD & SWANSON, NEILA 1989, ' Treatment of Malignant Fibrous Histiocytoma and Atypical Fibrous Xanthomas with Micrographic Surgery ', The Journal of Dermatologic Surgery and Oncology , vol. 15, no. 12, pp. 1287-1293. (elsevierpure.com)
- Malignant fibrous histiocytoma of bones: an important differential diagnosis of malignant bone neoplasms]. (bvsalud.org)
- Primary visceral malignant fibrous histiocytoma (MFH) is a rare disease, and few cases have been reported in the English literature. (biomedcentral.com)
- A case of late development of a high grade malignant fibrous histiocytoma at the site of a previously surgically treated giant cell tumor is reported. (uthscsa.edu)
- After chemotherapy, the tumor was resected and histologically showed no evidence of a recurrent giant cell tumor, only a high grade malignant fibrous histiocytoma. (uthscsa.edu)
- UPS (formerly called malignant fibrous histiocytoma [MFH]) is a rare type of bone cancer that usually starts in soft tissue, but it may form in bone. (cancer.gov)
Fibrous19
- Types include: benign fibrous histiocytoma: This tumor has also been termed benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, common fibrous histiocytoma, and more recently dermatofibroma. (wikipedia.org)
- Atypical Fibrous Histiocytoma of the Skin: Clinicopathologic. (lww.com)
- Atypical fibrous histiocytoma is an uncommon, poorly documented variant of cutaneous fibrous histiocytoma. (lww.com)
- We studied 59 cases of atypical fibrous histiocytoma to better characterize the clinicopathologic spectrum. (lww.com)
- We conclude that atypical fibrous histiocytoma has a broader clinicopathologic spectrum than previously realized. (lww.com)
- Provided that atypical fibrous histiocytoma is treated by complete excision, a benign outcome is to be expected in most cases. (lww.com)
- However, similar to the cellular and aneurysmal variants of fibrous histiocytoma, atypical fibrous histiocytoma shows a higher tendency to recur locally than ordinary fibrous histiocytoma and may rarely metastasize. (lww.com)
- Aneurysmal fibrous histiocytoma is a rare variant of cutaneous fibrous histiocytoma that results from blood vessel proliferation and haemorrhage into a fibrous histiocytoma. (bmj.com)
- This report describes the case of a 48 year old woman with a recurrent fibrous histiocytoma with prominent vasculature, which over a three year period recurred on two occasions, showing more progressive features of the aneurysmal variant. (bmj.com)
- Benign fibrous histiocytoma is a benign tumor composed of a mixture of fibroblastic and histiocytic cells. (alliedacademies.org)
- The diagnosis of benign fibrous histiocytoma located in the deeper tissues is clinically difficult and is confirmed histopathologically after excision. (alliedacademies.org)
- After detailed clinical and laboratory examinations, the lesion was excised in toto under general anesthesia, and histopathology revealed it to be a benign fibrous histiocytoma. (alliedacademies.org)
- A case of benign fibrous histiocytoma in a patient with previous Hodgkin's disease is reported. (elsevierpure.com)
- Benign fibrous histiocytoma consists of a proliferation of benign histiocytes in addition to inflammatory cells and occasional Reed-Sternberg-like cells. (elsevierpure.com)
- In this article, we describe for the first time a case of malign abdominal fibrous histiocytoma associated with a surgical sponge forgotten in the abdominal cavity a long time ago. (biomedcentral.com)
- Soft tissuefibrohistiocytic tumors - Benign fibrous histiocytoma (superficial). (healthline.com)
- Fibrous histiocytoma/dermatofibroma in children: the same as adults? (cincinnatichildrens.org)
- Watkins had a rare illness called Angiomatoid Fibrous Histiocytoma. (kivitv.com)
- Ulcerating, angiomatoid / angiosarcoma-like, and fibrous histiocytoma-like / fibroma-like variants have also been reported. (logicalimages.com)
Tumor5
- If you have noticed a lump or cyst on your dog it may be a Histiocytoma, a common (and benign) skin tumor that can develop on any breed. (petinsurancereview.com)
- A Histiocytoma is when an outer layer tissue (skin, the surface of the nose, throat, intestine, or lungs) forms a benign tumor or lump. (petinsurancereview.com)
- Most of the time the histiocytoma is small enough for easy removal and the diagnosis comes up on the biopsy report, confirming that the tumor is benign and will not grow back. (marvistavet.com)
- Immunohistochemical and immunoelectron study of major histocompatibility complex class-II antigen in canine cutaneous histiocytoma: its relation to tumor regression. (illumina.com)
- The histiocytoma is a common benign tumor of younger dogs (and the occasional cat). (marvistavet.com)
Dermatofibroma2
- The use of "histiocytoma" in these terms refers more to the morphologic appearance of some of the cells that comprise these lesions rather than their lineage: studies to date have not fully determined the lineage of the neoplastic cells in dermatofibroma tumors but recent cell marker studies suggest these cells originate from fibroblasts rather than histiocytes. (wikipedia.org)
- Dermatofibroma(also known as histiocytoma). (healthline.com)
Growths1
- Because there are other growths that can look just like the histiocytoma, it is important to get the right diagnosis as the other conditions may not be as benign. (marvistavet.com)
Histiocytes1
- A histiocytoma is a tumour consisting of histiocytes. (wikipedia.org)
Regression2
- On the average, a histiocytoma undergoes regression by itself within three months. (marvistavet.com)
- Any histiocytoma that is eroded or seems uncomfortable should be removed rather than waiting through the regression process. (marvistavet.com)
Dogs1
- Histiocytoma in dogs is most often found when you are petting your furry friend and notice the growth when you are scratching under their fur. (petinsurancereview.com)
Cytology1
- Cytology sample from a histiocytoma. (marvistavet.com)
Veterinarian1
- Your veterinarian might also recommend the removal of a histiocytoma that grows too rapidly or becomes infected. (petmd.com)
Adult1
- The typical histiocytoma patient is a young adult dog (usually less than 2 years of age) with a round eroded growth somewhere on the front half of its body but, of course, not every patient seems to have read the text book. (marvistavet.com)
Removal1
- Removal of the histiocytoma is the fastest route to resolution but, since they do go away on their own, leaving the growth alone is reasonable (as long as we know for sure it is a histiocytoma). (marvistavet.com)
Skin1
- The histiocytoma is a benign skin growth that usually goes away by itself within a couple of months. (marvistavet.com)
Cells2
- The histiocytoma results when Langerhans cells become tumorous and generate a visible growth. (marvistavet.com)
- The purple cells are histiocytoma cells. (marvistavet.com)
Remove1
- How much does it cost to remove a histiocytoma on a dog? (petmd.com)
Months1
- Any growth believed to be a histiocytoma that is still present after 3 months should be removed. (marvistavet.com)
Fibrous histiocytoma44
- Types include: benign fibrous histiocytoma: This tumor has also been termed benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, common fibrous histiocytoma, and more recently dermatofibroma. (wikipedia.org)
- malignant fibrous histiocytoma: This tumor is now termed undifferentiated pleomorphic sarcoma (UPS) because more recently developed immunohistochemistry and cytogenetic analyses suggest that its neoplastic cells most likely arise from mesenchymal stem cells or fibroblasts rather than histiocytes. (wikipedia.org)
- Fibrous histiocytoma was suspected based on the results of a core needle biopsy. (medscape.com)
- The gross specimen and histopathology of the LAM confirmed the diagnosis of malignant fibrous histiocytoma. (medscape.com)
- A gross photomacrographic cross-section image of a large malignant fibrous histiocytoma. (medscape.com)
- A pathologic image illustrates typical histologic findings of malignant fibrous histiocytoma. (medscape.com)
- Malignant fibrous histiocytoma is a tumor of late adulthood that occurs in men more commonly than women. (medscape.com)
- Cite this: Malignant Fibrous Histiocytoma (MFH) - Medscape - Mar 01, 2006. (medscape.com)
- Undifferentiated pleomorphic sarcoma (UPS), previously called malignant fibrous histiocytoma (MFH), is a soft tissue sarcoma (STS) that can occur anywhere in the body, but it usually occurs in the extremities (especially the thighs) or back of the abdomen (see the image below). (medscape.com)
- The malignant fibrous histiocytoma is only slightly hypodense to muscle and conceivably could be overlooked. (medscape.com)
- Historically, the term malignant fibrous histiocytoma (MFH) was applied to pleomorphic spindle cell neoplasms with fibroblastic and histiocytic differentiation. (medscape.com)
- Epithelioid fibrous histiocytoma is a rare and distinctive cutaneous neoplasm. (nih.gov)
- Most cases harbor ALK rearrangement and show ALK overexpression, which distinguish this neoplasm from conventional cutaneous fibrous histiocytoma and variants. (nih.gov)
- SQSTM1 and VCL have previously been shown to partner with ALK in one case each of epithelioid fibrous histiocytoma. (nih.gov)
- A retrospective archival review was performed to identify cases of epithelioid fibrous histiocytoma (2012-2016). (nih.gov)
- A 20 year old female had an angiomatoid malignant fibrous histiocytoma of her left upper eyelid extending into the orbit, frontal and temporal regions. (ijo.in)
- Malignant fibrous histiocytoma is a primitive mesenchymal tumor showing partial fibroblastic and histiocytic differentiation [1] . (ijo.in)
- Angiomatoid malignant fibrous histiocytoma was first described by En zinger [2] (1979). (ijo.in)
- In our knowledge, angiomatoid malignant fibrous histiocytoma of the upper eyelid extending into the peripheral orbital space, frontal and temporal regions, in a young female, is being reported for the first time. (ijo.in)
- John, Yanoff & Scheie [11] (1981) reported fibrous histiocytoma of the lower eyelid. (ijo.in)
- Ronan and Tso [12] (1978) reported a unique case of bilateral multiple pert-orbital fibrous histiocytoma with extensive involvement of the lids. (ijo.in)
- Malignant fibrous histiocytoma of soft tissue: an abandoned diagnosis. (orthobullets.com)
- Malignant fibrous histiocytoma (MFH) has been regarded as the most common soft-tissue sarcoma of adult life. (orthobullets.com)
- Malignant fibrous histiocytoma (MFH) is a rare neoplasm exhibiting a propensity for aggressive clinical behavior. (indexindex.com)
- Aims: We compared the clinical and pathological features of pleomorphic malignant fibrous histiocytoma (MFH)-like soft tissue sarcomas with and without myofibroblastic differentiation on electron microscopy. (johnshopkins.edu)
- This image shows Epithelioid Fibrous Histiocytoma - a variant where at least half the tumor consists of epithelioid cells . (webpathology.com)
- A malignant fibrous histiocytoma in his right gluteal fold was subsequently identified. (dundee.ac.uk)
- Introduction: The purpose of the study was to determine the risk factors influencing the prognosis of malignant fibrous histiocytoma. (muni.cz)
- Discussion: The authors have found the following risk factors of malignant fibrous histiocytoma survival: age over 60 years, marginal resection, deep localisation, histological grade III, size of the tumour exceeding 8cm, and the presence of metastasis at the time of diagnosis. (muni.cz)
- 1. ALK Rearrangement and Overexpression in an Unusual Cutaneous Epithelioid Tumor With a Peculiar Whorled "Perineurioma-like" Growth Pattern: Epithelioid Fibrous Histiocytoma. (nih.gov)
- 2. ALK rearrangement and overexpression in epithelioid fibrous histiocytoma. (nih.gov)
- 5. Spindle cell-predominant epithelioid fibrous histiocytoma. (nih.gov)
- 6. Epithelioid Fibrous Histiocytoma With Dot-Like Perinuclear ALK Expression and PRKAR2A-ALK Fusion. (nih.gov)
- 8. A subset of so-called dermal non-neural granular cell tumours are underlined by ALK fusions, further supporting the idea that they represent a variant of epithelioid fibrous histiocytoma. (nih.gov)
- 10. Epithelioid Fibrous Histiocytoma: A Concise Review. (nih.gov)
- 11. Atypical fibrous histiocytoma of the skin with CD30 and p80/ALK1 positivity and ALK gene rearrangement. (nih.gov)
- 12. Nonneural granular cell tumors and epithelioid fibrous histiocytoma: Similar but not the same. (nih.gov)
- 15. ALK Gene Fusions in Epithelioid Fibrous Histiocytoma: A Study of 14 Cases, With New Histopathological Findings. (nih.gov)
- 17. Epithelioid fibrous histiocytoma: three diagnostically challenging cases with novel ALK gene fusions, unusual storiform growth pattern, and a prominent spindled morphology. (nih.gov)
- 20. Report of an angiosarcoma mimic: cutaneous aneurysmal fibrous histiocytoma. (nih.gov)
- Check the list of NCI-supported cancer clinical trials that are now accepting patients with localized osteosarcoma and localized childhood malignant fibrous histiocytoma of bone . (cancerhelpessentiahealth.org)
- When osteosarcoma or malignant fibrous histiocytoma (MFH) spreads, it usually spreads to the lung . (cancerhelpessentiahealth.org)
- Osteosarcoma and malignant fibrous histiocytoma may spread to a distant bone and/or the lung. (cancerhelpessentiahealth.org)
- Check the list of NCI-supported cancer clinical trials that are now accepting patients with recurrent osteosarcoma and recurrent childhood malignant fibrous histiocytoma of bone . (cancerhelpessentiahealth.org)
Tumors1
- The use of "histiocytoma" in these terms refers more to the morphologic appearance of some of the cells that comprise these lesions rather than their lineage: studies to date have not fully determined the lineage of the neoplastic cells in dermatofibroma tumors but recent cell marker studies suggest these cells originate from fibroblasts rather than histiocytes. (wikipedia.org)
Tumour1
- A histiocytoma is a tumour consisting of histiocytes. (wikipedia.org)
Spindle cell1
- 7. Spindle cell variant of epithelioid cell histiocytoma (spindle cell histiocytoma) with ALK gene fusions: Cases series and review of the literature. (nih.gov)
Diagnosis1
- Because there are other growths that can look just like a histiocytoma, it is important to get the right diagnosis, as the other conditions may not be as benign. (vin.com)
Histiocytosis1
- The histiocytoma is not related to the malignant process called histiocytosis. (vin.com)
Study1
- The aim of this study was to describe our experience of perioperative treatment of pediatric patients undergoing en bloc kidney transplant. (bvsalud.org)
Case report1
- 3. Epithelioid cell histiocytoma with SQSTM1-ALK fusion: a case report. (nih.gov)
Patient1
- The typical histiocytoma patient is a young adult dog, usually less than two years of age, with a round eroded growth somewhere on the front half of its body. (vin.com)
Results1
- A histiocytoma results when Langerhans cells become tumorous and generate visible growth. (vin.com)
Material1
- Material y métodos: serie de casos en los que se realiza endarterectomÃa y retiro de stents de vasos coronarios entre el 1 de enero y el 30 de abril del 2011. (bvsalud.org)
Type1
- Myxofibrosarcoma had been classified as a type of histiocytoma. (wikipedia.org)