Tumors of the iris characterized by increased pigmentation of melanocytes. Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis and malignant melanoma of the choroid and ciliary body. Malignant melanoma of the iris often originates from preexisting nevi.
The most anterior portion of the uveal layer, separating the anterior chamber from the posterior. It consists of two layers - the stroma and the pigmented epithelium. Color of the iris depends on the amount of melanin in the stroma on reflection from the pigmented epithelium.
Diseases, dysfunctions, or disorders of or located in the iris.
A plant genus of the family IRIDACEAE that contains IRIP, a type-1 ribosome-inactivating protein, and iridals (TRITERPENES).
Tumors or cancer of the VULVA.
An erectile structure homologous with the penis, situated beneath the anterior labial commissure, partially hidden between the anterior ends of the labia minora.
Pathological processes of the VULVA.
The external genitalia of the female. It includes the CLITORIS, the labia, the vestibule, and its glands.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
Mucus-secreting glands situated on the posterior and lateral aspect of the vestibule of the vagina.
The female reproductive organs. The external organs include the VULVA; BARTHOLIN'S GLANDS; and CLITORIS. The internal organs include the VAGINA; UTERUS; OVARY; and FALLOPIAN TUBES.

Factors associated with elevated intraocular pressure in eyes with iris melanoma. (1/30)

AIM: To identify clinical factors associated with secondary elevated intraocular pressure (IOP) in eyes with iris malignant melanoma METHODS: A retrospective case series of 169 consecutive patients with microscopically confirmed iris malignant melanoma. The main outcome measure was the presence of tumour induced secondary elevated IOP. Cox proportional regression models were used to calculate the relation of clinical features to elevated IOP. RESULTS: Of 169 patients with microscopically proved iris melanoma, 50 (30%) presented with tumour induced secondary elevated IOP. The mean pressure in those eyes with elevated IOP at diagnosis was 33 mm Hg (median 31 mm Hg, range 23-65 mm Hg). The tumour configuration was nodular in 23 (46%) and diffuse in 27 (54%) with a mean base dimension of 7.4 mm and thickness of 2.0 mm. Invasion of the angle structures by melanoma seeds was visible for a mean of 7 clock hours (median 7, range 0-12 clock hours). The mechanism of elevated IOP was judged to be outflow obstruction from tumour invasion into the trabecular meshwork. There were no cases of neovascular glaucoma. The tumour was ultimately managed with enucleation in 30 patients (60%), local resection (iridectomy, iridocyclectomy, or iridocyclogoniectomy) in 11 (22%), and plaque radiotherapy in five (10%). In four cases (8%), observation of cytologically low grade tumour was the patient's preference. Using multivariate analysis, the clinical factors at initial evaluation associated with tumour induced secondary elevated IOP from iris melanoma included increasing extent of tumour seeding in the anterior chamber angle (p=0.01) and poor visual acuity at presentation (p=0.02). CONCLUSIONS: Microscopically confirmed iris melanoma demonstrates tumour related elevated IOP in 30% cases at the time of presentation, usually secondary to tumour involvement of the trabecular meshwork obstructing aqueous outflow. Enucleation is necessary in the majority of these patients (60%) as opposed to those cases without elevated intraocular pressure (18%).  (+info)

Primary iris melanoma: diagnostic features and outcome of conservative surgical treatment. (2/30)

AIMS: To describe features influencing the management of primary iris melanoma and report the outcome of conservative surgical treatment of patients diagnosed with this condition in a tertiary referral academic setting over a 20 year period. METHODS: Retrospective non-comparative case series of consecutive patients diagnosed with iris melanoma from 1980-2000 using medical records from the University of Sydney Department of Ophthalmology and NSW Cancer Registry RESULTS: 51 cases were identified. The most common presentation was growth of a previously noted pigmented lesion. Initial management was either observation or local resection (two had enucleations) with iris reconstruction where possible (23.8%). The mean follow up was 8.7 years (range 1-17 years). Vision of 6/12 or better was maintained in the majority (78.6%) treated by local resection. Pupil reconstruction significantly reduced reported postoperative glare symptoms. Four patients had features suggestive of local recurrence and there was no documented metastatic disease or death from iris melanoma in this series. Histologically, the majority were spindle B cell melanomas. Clinical features including prominent tumour vascularity, rapid growth, and heterogeneous pigmentation were each significantly associated with an epithelioid cell component. Involvement of the iridocorneal angle was frequently associated with ciliary body invasion. CONCLUSIONS: Management decisions for iris melanoma will depend on the clinical features. Mixed or epithelioid histology is more likely in the presence of two or more of the features of malignancy and may justify earlier intervention. When treatment is undertaken, local resection achieves long term tumour clearance with an acceptable morbidity. In resecting iris melanoma, careful assessment for iridocorneal angle involvement is important in treatment planning. Iris reconstruction has a useful role in reducing postoperative photophobia.  (+info)

Uveal melanomas express vascular endothelial growth factor and basic fibroblast growth factor and support endothelial cell growth. (3/30)

BACKGROUND: Tumour microvascularity is a significant determinant of prognosis for a large number of different tumours, including uveal melanoma. The development of blood vessels within these and other tumours is partly controlled by soluble pro-angiogenic cytokines, of which basic fibroblast growth factor (bFGF) and vascular endothelial growth factor-A (VEGF) are the best described. METHODS: Because VEGF has been inconsistently found within uveal melanomas and bFGF is described as an autocrine growth factor in cutaneous melanoma, the authors looked at the expression of these cytokines in uveal melanomas using immunohistochemistry and reverse transcriptase polymerase chain reaction (RT-PCR). The cross talk between uveal melanoma cells and endothelial cells was then assessed in an in vitro co-culture model. RESULTS: While most tumour cells expressed bFGF at the protein level by immunohistochemistry (89%), relatively few (22%) expressed VEGF, and this was of limited extent. All 20 tumours tested by RT-PCR contained mRNA for both bFGF and VEGF. Co-culture experiments using an ATP based bioassay showed that uveal melanomas could support the growth of a rat brain endothelial cell line (GPNT) and human umbilical vein endothelial cells (HUVEC), and that this could be modulated by cytokines and anti-cytokine antibodies. CONCLUSION: These results suggest that angiogenesis within uveal melanoma may be the result of a complex interplay between endothelial and tumour cells, and that bFGF and VEGF could play a part.  (+info)

Lack of detection of feline leukemia and feline sarcoma viruses in diffuse iris melanomas of cats by immunohistochemistry and polymerase chain reaction. (4/30)

Diffuse iris melanoma was confirmed by light-microscopic examination in 10 formalin-fixed, paraffin-embedded globes from 10 cats. To determine if feline leukemia virus or a replication defective feline leukemia virus, feline sarcoma virus, was present in these anterior uveal melanomas, immunohistochemistry and polymerase chain reaction for feline leukemia virus were utilized. Immunohistochemical staining for feline leukemia virus glycoprotein 70 was performed on all 10 tumors using an avidin-biotin complex technique. The DNA was extracted from each specimen and a 166-base pair region of the feline leukemia virus long terminal repeat was targeted by polymerase chain reaction. Immunohistochemical staining for feline leukemia virus glycoprotein 70 and polymerase chain reaction amplification of a feline leukemia virus long terminal repeat region were negative in all cases. Feline leukemia virus/feline sarcoma virus was not detected in any neoplasms and therefore was unlikely to play a role in the tumorigenesis of these feline diffuse iris melanomas.  (+info)

Tumor necrosis factor alpha increases and alpha-melanocyte-stimulating hormone reduces uveal melanoma invasion through fibronectin. (5/30)

Iris melanomas are less likely to metastasize than posterior compartment melanomas. The anterior chamber of the eye is an immunosuppressed microenvironment where a wide range of immunosuppressive factors in aqueous humor contribute to the immune privilege. One such factor is alpha-melanocyte-stimulating hormone, a potent anti-inflammatory neuropeptide that exhibits efficacy in many studies of acute and chronic inflammation. The aim of this study was to investigate whether the different metastatic behavior of iris melanomas versus posterior compartment melanomas might be explained by the differing immunosuppressive/anti-inflammatory environments of these tumors in vivo. To investigate this hypothesis, we studied the effect of human aqueous and vitreous fluids, of the proinflammatory cytokine tumor necrosis factor alpha, and of the anti-inflammatory peptides alpha-melanocyte-stimulating hormone and melanocyte-stimulating hormone 11-13 (KP-D-V) on the invasion of three human uveal melanoma cell lines through human fibronectin. Fresh aqueous humor samples significantly decreased the invasion in two out of three uveal melanoma cell lines. In contrast, vitreous humor did not reduce invasion. Tumor necrosis factor alpha significantly increased the invasiveness of uveal melanoma cell lines by approximately 50%-80% over 20 h. Full-length alpha-melanocyte-stimulating hormone, at concentrations present in the aqueous humor (10-9 M), as well as melanocyte-stimulating hormone 11-13 (KP-D-V) reduced the invasion of cells through human fibronectin by 45%-50% and also protected uveal melanoma cells from the pro-invasive actions of tumor necrosis factor alpha. These data are consistent with inflammation playing a major role in affecting the metastatic ability of uveal melanomas. Thus, ocular microenvironments that differ in their immunosuppressive/anti-inflammatory properties may influence the invasiveness of developing tumors.  (+info)

Congenital adenoma of the iris and ciliary body: light and electron microscopic observations. (6/30)

A 23-year-old man had a lesion in the right inferior iris which appeared to have enlarged since it was first seen when the patient was aged 5 years. The lesion was excised by a partial iridocyclectomy. Histopathologically the neoplasm was composed of both pigmented and non-pigmented cells. Pseudoacini, containing acid mucopolysaccharides, were present throughout the tumour matrix. Electron microscopically the non-pigmented cells were found to possess a convoluted plasmalemma, abundant rough endoplasmic reticulum, and numerous desmosomes and gap junctions. The pigmented cells contained large, round, mature melanosomes, occasional premelanosomes, and desmosomes, which resembled the posterior pigment epithelium of the iris. The intercellular matrix contained fine collagen fibrils resembling vitreous. We believe that this neoplasm represents a congenital adenoma of the ciliary body and iris.  (+info)

Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. (7/30)

AIM: To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. METHODS: Cross sectional study of 65 patients with posterior uveal melanoma and 218 controls. Iris colour, iris freckles, iris naevi, and choroidal naevi were recorded for each eye of each patient. RESULTS: Iris freckles were present in 40 (61.5%) patients with melanoma and 135 (61.9%) controls (p = 0.494). Iris naevi were present in four (6.2%) patients with melanoma and nine (4.1%) controls (p = 0.955). Choroidal naevi were present in 12 (18.5%) patients with melanoma and 38 (17.4%) controls (p = 0.815). CONCLUSION: This study did not detect an association between posterior uveal melanoma and iris freckles, iris naevi, or choroidal naevi.  (+info)

The Finger iridectomy technique: small incision biopsy of anterior segment tumours. (8/30)

AIMS: To develop a minimally invasive, maximally effective method to biopsy anterior segment tumours. METHODS: A 25 gauge aspiration cutter (vitrector) was used to biopsy anterior segment tumours. The probe was introduced under sodium hyaluronate 1% and through a 1 mm incision. Aspiration (600 mm Hg) cutting (300 cpm) was performed to obtain specimens for cytology and histopathology. RESULTS: Diagnostic material was obtained in nine of 10 (90%) cases. Diagnoses included iris naevus, iris stroma, malignant melanoma, melanocytoma, epithelial inclusion cyst, and sarcoid granuloma. All corneal wounds were self sealing. One patient developed a transient postoperative increase in intraocular pressure. Within the follow up of this study, no patients suffered intraocular haemorrhage, infection, cataract or vision loss. CONCLUSION: The Finger iridectomy technique was a minimally invasive and very effective biopsy technique. Aspiration cutting yielded relatively large pieces of tissue (and cells) used for cytopathological and histopathological evaluation. Small incision surgery allowed for rapid rehabilitation and no significant complications.  (+info)

Iris neoplasms refer to abnormal growths or tumors that develop in the iris, which is the colored part of the eye. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Benign iris neoplasms are typically slow-growing and do not spread to other parts of the body. Malignant iris neoplasms, on the other hand, can grow quickly and may spread to other parts of the eye or nearby structures, such as the ciliary body or choroid.

Iris neoplasms can cause various symptoms, including changes in the appearance of the eye, such as a visible mass or discoloration, pain, redness, light sensitivity, blurred vision, or changes in the size or shape of the pupil. The diagnosis of iris neoplasms typically involves a comprehensive eye examination, including a visual acuity test, refraction, slit-lamp examination, and sometimes imaging tests such as ultrasound or optical coherence tomography (OCT).

Treatment options for iris neoplasms depend on the type, size, location, and severity of the tumor. Small, benign iris neoplasms may not require treatment and can be monitored over time. Larger or malignant iris neoplasms may require surgical removal, radiation therapy, or other treatments to prevent complications or spread to other parts of the eye or body. It is essential to seek medical attention promptly if you experience any symptoms of iris neoplasms or notice any changes in your vision or the appearance of your eyes.

In medical terms, the iris refers to the colored portion of the eye that surrounds the pupil. It is a circular structure composed of thin, contractile muscle fibers (radial and circumferential) arranged in a regular pattern. These muscles are controlled by the autonomic nervous system and can adjust the size of the pupil in response to changes in light intensity or emotional arousal. By constricting or dilating the iris, the amount of light entering the eye can be regulated, which helps maintain optimal visual acuity under various lighting conditions.

The color of the iris is determined by the concentration and distribution of melanin pigments within the iris stroma. The iris also contains blood vessels, nerves, and connective tissue that support its structure and function. Anatomically, the iris is continuous with the ciliary body and the choroid, forming part of the uveal tract in the eye.

Iris diseases refer to a variety of conditions that affect the iris, which is the colored part of the eye that regulates the amount of light reaching the retina by adjusting the size of the pupil. Some common iris diseases include:

1. Iritis: This is an inflammation of the iris and the adjacent tissues in the eye. It can cause pain, redness, photophobia (sensitivity to light), and blurred vision.
2. Aniridia: A congenital condition characterized by the absence or underdevelopment of the iris. This can lead to decreased visual acuity, sensitivity to light, and an increased risk of glaucoma.
3. Iris cysts: These are fluid-filled sacs that form on the iris. They are usually benign but can cause vision problems if they grow too large or interfere with the function of the eye.
4. Iris melanoma: A rare type of eye cancer that develops in the pigmented cells of the iris. It can cause symptoms such as blurred vision, floaters, and changes in the appearance of the iris.
5. Iridocorneal endothelial syndrome (ICE): A group of rare eye conditions that affect the cornea and the iris. They are characterized by the growth of abnormal tissue on the back surface of the cornea and can lead to vision loss.

It is important to seek medical attention if you experience any symptoms of iris diseases, as early diagnosis and treatment can help prevent complications and preserve your vision.

I am not aware of a specific medical definition for "Iris Plant." The term "iris" in a medical context usually refers to the colored part of the eye that regulates the size of the pupil and controls the amount of light that enters the eye.

However, the "Iris Plant" (Iris spp.) is a type of perennial flowering plant that belongs to the family Iridaceae. It is native to temperate regions of the Northern Hemisphere, although there are also some species found in tropical and subtropical areas. The iris plant has long, sword-shaped leaves and showy flowers that come in various colors, including blue, purple, yellow, white, and red.

If you have any further questions or need information related to a medical topic, please let me know!

Vulvar neoplasms refer to abnormal growths or tumors in the vulvar region, which is the exterior female genital area including the mons pubis, labia majora, labia minora, clitoris, and the vaginal vestibule. These neoplasms can be benign (non-cancerous) or malignant (cancerous).

Benign vulvar neoplasms may include conditions such as vulvar cysts, fibromas, lipomas, or condylomas (genital warts). They are typically slow-growing and less likely to spread or invade surrounding tissues.

Malignant vulvar neoplasms, on the other hand, are cancers that can invade nearby tissues and potentially metastasize (spread) to distant parts of the body. The most common types of malignant vulvar neoplasms are squamous cell carcinoma, vulvar melanoma, and adenocarcinoma.

Early detection and treatment of vulvar neoplasms are essential for improving prognosis and reducing the risk of complications or recurrence. Regular gynecological examinations, self-examinations, and prompt attention to any unusual symptoms or changes in the vulvar area can help ensure timely diagnosis and management.

The clitoris is an important female sex organ that is primarily responsible for sexual arousal and pleasure. It is a small, highly sensitive piece of tissue located at the front of the vulva, where the labia minora meet. The clitoris is made up of two parts: the visible part, known as the glans clitoris, and the hidden part, called the corpora cavernosa and crura.

The glans clitoris is a small knob-like structure that is covered by a hood, or prepuce, and is located at the top of the vulva. It contains a high concentration of nerve endings, making it highly sensitive to touch and stimulation. The corpora cavernosa and crura are the internal parts of the clitoris, which are made up of sponge-like erectile tissue that becomes engorged with blood during sexual arousal, leading to clitoral erection.

The clitoris plays a crucial role in female sexual response and pleasure. During sexual arousal, the clitoris swells and becomes more sensitive to touch, which can lead to orgasm. The clitoris is also an important source of sexual pleasure during masturbation and partnered sexual activity. Despite its importance in female sexuality, the clitoris has historically been overlooked or stigmatized in many cultures, leading to a lack of understanding and education about this vital organ.

Vulvar diseases refer to a range of medical conditions that affect the vulva, which is the external female genital area including the mons pubis, labia majora and minora, clitoris, and the vaginal opening. These conditions can cause various symptoms such as itching, burning, pain, soreness, irritation, or abnormal growths or lesions. Some common vulvar diseases include:

1. Vulvitis: inflammation of the vulva that can be caused by infection, allergies, or irritants.
2. Lichen sclerosus: a chronic skin condition that causes thin, white patches on the vulva.
3. Lichen planus: an inflammatory condition that affects the skin and mucous membranes, including the vulva.
4. Vulvar cancer: a rare type of cancer that develops in the tissues of the vulva.
5. Genital warts: caused by human papillomavirus (HPV) infection, these are small growths or bumps on the vulva.
6. Pudendal neuralgia: a nerve condition that causes pain in the vulvar area.
7. Vestibulodynia: pain or discomfort in the vestibule, the area surrounding the vaginal opening.

It is important to consult a healthcare professional if experiencing any symptoms related to vulvar diseases for proper diagnosis and treatment.

The vulva refers to the external female genital area. It includes the mons pubis (the pad of fatty tissue covered with skin and hair that's located on the front part of the pelvis), labia majora (the outer folds of skin that surround and protect the vaginal opening), labia minora (the inner folds of skin that surround the vaginal and urethral openings), clitoris (a small, sensitive organ located at the front of the vulva where the labia minora join), the external openings of the urethra (the tube that carries urine from the bladder out of the body) and vagina (the passageway leading to the cervix, which is the lower part of the uterus).

It's important to note that understanding the anatomy and terminology related to one's own body can help facilitate effective communication with healthcare providers, promote self-awareness, and support overall health and well-being.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

Bartholin's glands are two small exocrine glands located in the female reproductive system. They are named after the Danish anatomist and surgeon Caspar Bartholin the Younger, who described them in 1677. These glands are about the size of a pea and are situated on either side of the vaginal opening, just inside the labia majora (the outer folds of skin surrounding the vaginal opening).

Bartholin's glands produce and secrete a mucus-like fluid that helps lubricate the vaginal opening, making sexual intercourse more comfortable. The fluid is released through small ducts that open into the vestibule, the area between the labia minora (the inner folds of skin surrounding the vaginal opening) and the hymen.

In some cases, Bartholin's glands can become blocked, causing a cyst or abscess to form. These conditions may require medical treatment, such as antibiotics, drainage, or surgical removal of the cyst or abscess.

Female genitalia refer to the reproductive and sexual organs located in the female pelvic region. They are primarily involved in reproduction, menstruation, and sexual activity. The external female genitalia, also known as the vulva, include the mons pubis, labia majora, labia minora, clitoris, and the external openings of the urethra and vagina. The internal female genitalia consist of the vagina, cervix, uterus, fallopian tubes, and ovaries. These structures work together to facilitate menstruation, fertilization, pregnancy, and childbirth.

"Vulvar Cancer". Gynecologic Neoplasms. Armenian Health Network, Health.am. 2005. Retrieved 2007-11-08. Wohlmuth, Christoph; ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris; May, Taymaa; Vicus, Danielle; Gien, Lilian T.; Laframboise, Stéphane (April 2020 ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris; May, Taymaa; Vicus, Danielle; Gien, Lilian T.; Laframboise, Stéphane (April 2020 ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris (2021-06-14). "Vulvar Melanoma: Molecular Characteristics, Diagnosis, Surgical ...
Iris and conjuctival tumors (melanomas) - Present as a dark spot. Any spot which continues to grow on the iris and the ... These tumors can occur in the choroid, iris and ciliary body. The latter are sometimes called iris or ciliary body melanoma. ... Eye neoplasms can affect all parts of the eye, and can be a benign tumor or a malignant tumor (cancer). Eye cancers can be ... Iridectomy - Removal of the affected piece of the iris Choroidectomy - Removal of the choroid layer (the vascular tissue ...
The limbal ring is a visible dark ring around the iris of the eye composed of darkened areas of the corneal limbus. The corneal ... The corneal limbus is a common site for the occurrence of corneal epithelial neoplasm. Aniridia, a developmental anomaly of the ... iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus. The limbus sign shows ...
Neoplasm - Melanomas can also be very lightly pigmented, and a lighter colored iris may be a rare manifestation of metastatic ... Neoplasm - Nevi and melanomatous tumors. Iridocorneal endothelium syndrome Iris ectropion syndrome Fuchs heterochromic ... The lighter eye is typically regarded as the affected eye as it usually shows iris hypoplasia. It may affect an iris completely ... In complete heterochromia, one iris is a different color from the other. In sectoral heterochromia, part of one iris is a ...
... iris neoplasms MeSH C11.941.375.385 - iritis MeSH C11.941.855 - uveal neoplasms MeSH C11.941.855.198 - choroid neoplasms MeSH ... uveal neoplasms MeSH C11.319.494.198 - choroid neoplasms MeSH C11.319.494.400 - iris neoplasms MeSH C11.338.133 - blepharitis ... conjunctival neoplasms MeSH C11.319.421 - eyelid neoplasms MeSH C11.319.457 - orbital neoplasms MeSH C11.319.475 - retinal ... iris neoplasms MeSH C11.941.879 - uveitis MeSH C11.941.879.780 - panuveitis MeSH C11.941.879.780.500 - ophthalmia, sympathetic ...
... neoplasm Esophageal varices Esophoria Esotropia Essential fatty acid deficiency Essential hypertension Essential iris atrophy ...
These include light iris color, generally lower levels of melanin (light and untanned skin tones), exposure to arc welding due ... Choroidal nevus (plural: nevi) is a type of eye neoplasm that is classified under choroidal tumors as a type of benign (non- ... around the iris, or the rear end of the eye. Nevi are usually darkly pigmented tumors because they comprise melanocytes. Dr. ...
Other causes of ptosis include eyelid neoplasms, neurofibromas or cicatrization after inflammation or surgery. Mild ptosis may ... iris and areola hypopigmentation and anhidrosis caused by paresis of the superior tarsal muscle. Acquired Horner syndrome may ...
About 0.5% to 1% of all primary malignant lung tumors are childhood tumors of the lung, making it a rare form of neoplasm. ... iris rubeosis, hypopyon, hyphema, buphthalmia, orbital cellulites and exophthalmia. About sixty percent of cases are unilateral ... Retinoblastoma is a rare form of eye neoplasm (found in the retina) that is mostly found in children, being the most common ... This type of malignant neoplasm mimics pancreatic development at 7 weeks of gestation and tends to affect, most commonly, young ...
Café-au-lait spots are the most common sign of NF1, but other symptoms include lisch nodules of iris, cutaneous neurofibromas ( ... which develops myeloproliferative neoplasms similar to those found in NF1 juvenile myelomonocytic leukemia/JMML) were used to ... astrocytic neoplasms, phaeochromocytomas and breast cancer. No effective therapy NF1 yet exists. Instead, people with ... an oral selective MEK inhibitor used previously in several advanced adult neoplasms. The children enrolled in the study ...
Nagtegaal, Iris D; Odze, Robert D; Klimstra, David; Paradis, Valerie; Rugge, Massimo; Schirmacher, Peter; Washington, Kay M; ... Only 1 or 2% of clinically significant pancreas neoplasms are PanNETs. The majority of PanNETs are benign, while some are ... are neuroendocrine neoplasms that arise from cells of the endocrine (hormonal) and nervous system within the pancreas. PanNETs ... "Pathophysiology and Treatment of Pancreatic Neuroendocrine Neoplasms (PNENS): New Developments". Pathophysiology and Treatment ...
August 13 - English astronomer John Russell Hind discovers asteroid 7 Iris from London. October 18 - J. R. Hind discovers ... Émile Küss and Charles-Emmanuel Sédillot perform the first recorded biopsies on neoplasms. Ignaz Semmelweis studies and ...
Nagtegaal, Iris D.; Odze, Robert D.; Klimstra, David; Paradis, Valerie; Rugge, Massimo; Schirmacher, Peter; Washington, Kay M ... Inzani, Frediano; Rindi, Guido (2017). "1. Classifications of neuroendocrine neoplasms". In Pacak, Karel; Taieb, David (eds.). ... Iris D.; Klimstra, David S.; Rugge, Massimo; Schirmacher, Peter; Lazar, Alexander J.; Odze, Robert D.; Carneiro, Fatima; ... Iris; Eggermont, Alexander M. M. (1 February 2020). "European consensus-based interdisciplinary guideline for melanoma. Part 1 ...
True iris melanomas, originating from within the iris as opposed to originating elsewhere and invading the iris, are distinct ... Kumar, Vinay (2009). "Uvea: Neoplasms". Robbins and Cotran Pathologic Basis of Disease, Professional Edition (8th ed.). ... Uveal tumors can originate from melanocytes residing within the iris. Benign melanocytic tumors, such as iris freckles and ... in which case they are classified as iris melanomas. Though derived from uveal melanocytes, iris melanomas share more in common ...
Tumor may invade locally to involve the iris or anterior retina, or through the cornea or sclera. In advanced cases, tumor may ... Shields, Jerry A.; Eagle, Ralph C.; Shields, Carol L.; De Potter, Patrick (December 1996). "Congenital Neoplasms of the ... while the most common signs are leukocoria and presence of a mass in the iris or ciliary body. Other signs and symptoms include ...
... uveal neoplasms MeSH C04.588.364.978.223 - choroid neoplasms MeSH C04.588.364.978.400 - iris neoplasms MeSH C04.588.443.353 - ... skull base neoplasms MeSH C04.588.149.828 - spinal neoplasms MeSH C04.588.180.260 - breast neoplasms, male MeSH C04.588.180.390 ... bile duct neoplasms MeSH C04.588.274.120.250.250 - common bile duct neoplasms MeSH C04.588.274.120.401 - gallbladder neoplasms ... femoral neoplasms MeSH C04.588.149.721 - skull neoplasms MeSH C04.588.149.721.450 - jaw neoplasms MeSH C04.588.149.721.450.583 ...
Neoplasms of the Eye". Cancer Medicine. Hamilton, Ontario: BC Decker Inc. ISBN 978-1-55009-213-4. Naeem, Zishan; Reddy, M. ... Bowman, Richard; Evans, Jennifer R.; Gilbert, Clare; Gordon, Iris; Gupta, Sunchita; Malik, Aeesha NJ; Mariotti, Silvio (2022 ... Roarty JD, McLean IW, Zimmerman LE (November 1988). "Incidence of second neoplasms in patients with bilateral retinoblastoma". ...
Abdominal neoplasms Aberrant subclavian artery Ablepharon macrostomia syndrome Abnormal systemic venous return Abruzzo-Erickson ... Amelia cleft lip palate hydrocephalus iris coloboma Amelia facial dysmorphism Amelia X linked Amelogenesis Amelogenesis ... X-linked Adrenal incidentaloma Adrenal insufficiency Adrenal macropolyadenomatosis Adrenal medulla neoplasm Adrenocortical ... Abdominal cystic lymphangioma Abdominal defects Abdominal musculature absent microphthalmia joint laxity Abdominal neoplasm / ...
... neoplasms, and cysts are skin lesions that develop from the epidermal layer of the skin. Aberrant basal cell carcinoma ... infantile postinfectious iris-like purpura and edema, medallion-like purpura, purpura en cocarde avec oedema, Seidlmayer ... an overview with emphasis on the myeloid neoplasms". Chem. Biol. Interact. 184 (1-2): 16-20. doi:10.1016/j.cbi.2009.10.009. ... neoplasms invading or aberrantly present in the dermis. Acquired progressive lymphangioma (benign lymphangioendothelioma) Acral ...
Short limb dwarf lethal Colavita-Kozlowski type Short limb dwarf lethal Mcalister-Crane type Short limb dwarf oedema iris ... muscular atrophy Spinal atrophy ophthalmoplegia pyramidal syndrome Spinal cord disorder Spinal cord injury Spinal cord neoplasm ... corneal dystrophy Spinocerebellar degenerescence book type Spirochetes disease Spirurida infections Spleen neoplasm Splenic ...
IRIS, an international study that compared interferon/cytarabine combination and the first of these new drugs imatinib, with ... May 2016). "The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia". Blood. ... It is a type of myeloproliferative neoplasm associated with a characteristic chromosomal translocation called the Philadelphia ... classification of the myeloid neoplasms". Blood. 100 (7): 2292-302. doi:10.1182/blood-2002-04-1199. PMID 12239137. S2CID ...
Cabrera, Walter E.; Schrooten, Iris; De Broe, Marc E.; D'Haese, Patrick C. (1999). "Strontium and Bone". Journal of Bone and ... Radioactive strontium for treating incurable pain in skeletal neoplasms]. Deutsche Medizinische Wochenschrift (in German). 98 ( ...
... s are one of the more common breeds to have non-white irises. A description and depiction of the Wichienmaat ( ... The majority of deaths were caused by neoplasms, mainly mammary tumours. The Siamese also has a higher rate of morbidity. They ...
... one or more pigmented lesions in the iris. The Classical (1990) definition uses the following criteria: 1) 100 or more ... Melanocytic nevi and neoplasms, Syndromes affecting the skin). ...
Baldewijns, Marcella M.L.; Van Vlodrop, Iris J.H.; Schouten, Leo J.; Soetekouw, Patricia M.M.B.; De Bruïne, Adriaan P.; Van ... which is an assessment based on the microscopic morphology of a neoplasm with haematoxylin and eosin (H&E staining). This ... "Magnetic resonance imaging in the diagnosis and staging of renal and perirenal neoplasms". Radiology. 154 (3): 709-15. doi: ... classification of genitourinary tumours recognizes over 40 subtypes of renal neoplasms. Since the publication of the latest ...
... cerebellar vermis aplasia Coloboma hair abnormality Coloboma of choroid and retina Coloboma of eye lens Coloboma of iris ... Carrington syndrome Cartilage hair hypoplasia like syndrome Cartilage-hair hypoplasia Cartilaginous neoplasms Cartwright-Nelson ... hypoxia Cerebral malformations hypertrichosis claw hands Cerebral palsy Cerebral thrombosis Cerebral ventricle neoplasms ... Choriocarcinoma Chorioretinitis Chorioretinopathy dominant form microcephaly Choroid plexus cyst Choroid plexus neoplasms ...
Tiu R. V.; Sekeres M. A. (2014). "Making sense of the myelodysplastic/myeloproliferative neoplasms overlap syndromes". Current ... tiny tan or brown-colored spots on the iris of the eye) Various bone deformations including bowing of the legs below the knee, ... neoplasms, and cysts, Pediatric cancers, Rare cancers). ...
Milosevic, Vladan; Kopecka, Joanna; Salaroglio, Iris C.; Libener, Roberta; Napoli, Francesca; Izzo, Stefania; Orecchia, Sara; ... Connective and soft tissue neoplasms, Diseases of pleura, Infectious causes of cancer, Occupational diseases, Pleura neoplasia ...
In the eyes, the ciliary muscles, iris dilator muscle, and iris sphincter muscle are types of smooth muscles. The iris dilator ... Intravascular leiomyomatosis is a benign neoplasm that extends through the veins; angioleiomyoma is a benign neoplasm of the ... Multiunit smooth muscle is found in the trachea, the iris of the eye, and lining the large elastic arteries. However, the terms ... and sphincter muscles are contained in the iris and contract in order to dilate or constrict the pupils. The ciliary muscles ...
Di Nisio, Marcello; Wichers, Iris M; Middeldorp, Saskia (2018-02-25). Cochrane Vascular Group (ed.). "Treatment for superficial ... catheters Inflammatory diseases/some autoimmune diseases Nephrotic syndrome Obesity Infection HIV Myeloproliferative neoplasms ...
... On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a ...
"Vulvar Cancer". Gynecologic Neoplasms. Armenian Health Network, Health.am. 2005. Retrieved 2007-11-08. Wohlmuth, Christoph; ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris; May, Taymaa; Vicus, Danielle; Gien, Lilian T.; Laframboise, Stéphane (April 2020 ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris; May, Taymaa; Vicus, Danielle; Gien, Lilian T.; Laframboise, Stéphane (April 2020 ... Wohlmuth, Christoph; Wohlmuth-Wieser, Iris (2021-06-14). "Vulvar Melanoma: Molecular Characteristics, Diagnosis, Surgical ...
A case is presented of an intraocular T-cell lymphoma mimicking a ring melanoma of the iris and being the first manifestation ... Iris Neoplasms / pathology* * Lymphoma, T-Cell / pathology* * Melanoma / pathology* * Middle Aged * Uveal Neoplasms / pathology ... A case is presented of an intraocular T-cell lymphoma mimicking a ring melanoma of the iris and being the first manifestation ... Nodules had developed in the circumference and the lesion now imitated a malignant melanoma of the iris, which was also the ...
... ocular neoplasms (eg, retinoblastoma, iris melanomas, medulloepitheliomas, [9] uveitis, and vascular anomalies (eg, juvenile ... Rarely, an iris fluorescein angiogram may be needed if early iris neovascularization is suspected as an underlying cause of the ... Iris neovascularization can also result in a hyphema due to fragile iris vessels that can bleed from intraoperative ... from the iris or iris root, or from the corneoscleral wounds. Wounds located more posteriorly tend to bleed more. ...
... findings of vitreous seeding or extension into the iris and anterior chamber may help to diagnose retinoblastoma. ... positron-emission tomography might differentiate dysplasia and neoplasms, but this differentiation has not been confirmed for ...
When examining the iris, abnormalities to look for are dyscoria, anisocoria, iris swelling, changes in iris color ( ... Although most commonly due to inflammation, breakdown of the blood-aqueous barrier also occurs with intraocular neoplasms. ... iris atrophy, heterochromia, persistent pupillary membranes, iris swelling. ... If a dense white opacity is present, the cornea is examined for adherent iris tissue (synechia). Such a lesion is referred to ...
Although there is no gender predilection, iris melanomas occur more frequently in Caucasians with a light colored iris versus ... There is no consistent evidence linking iris melanoma with UV light or environmental exposure ... Iris melanoma is the most common primary neoplasm of the iris and account for approximately 5% of all uveal melanomas. The ... Iris melanoma is the most common primary neoplasm of the iris and account for approximately 5% of all uveal melanomas. The ...
Dive into the research topics of Rapidly growing iris melanocytoma with secondary glaucoma in a 6-year-old child. Together ... Rapidly growing iris melanocytoma with secondary glaucoma in a 6-year-old child. ...
NEUROENDOCRINE CARCINOMAS ARISING IN A BACKGROUND OF BILIARY INTRAEPITHELIAL NEOPLASIA AND INTRACHOLECYSTIC PAPILLARY NEOPLASM ... Iris D. Nagtegaal et al. IMPACT OF DELAYED SCREENING INVITATIONS DUE TO COVID-19 ON OUTCOMES OF THE DUTCH FIT-BASED COLORECTAL ...
... autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms ... iris hamartomas); (5) a distinctive osseous lesion, such as sphenoid dysplasia or thinning of the long bones of the cortex with ... However, some true low-grade neoplasms and, rarely, high-grade glial neoplasms, will not enhance with gadolinium. The use of ... Neurofibromatosis 1 and intracranial neoplasms of childhood. Author Roger J Packer MD See Contributor Disclosures ...
in IRIS) by World Health Organization.. Material type: Text; Format: print Publication details: Geneva : World Health ... IRIS GIFT HINARI PubMed Global Health Library AFRO (AIM) EMRO (IMEMR) PAHO (LILACS) SEARO (IMSEAR) WIPRO (WPRIM) ...
Iris Udasin. *PROF-CLIN, Robert Wood Johnson Medical School (RWJMS), Occupational Medicine ... Dive into the research topics where Iris Udasin is active. These topic labels come from the works of this person. Together they ...
IRIS CHROMATOPHORES. MERKEL CELL CA. ULTIMOBRANCHIAL BODY--PARAFOLLICULAR C-CELLS OF THE THYROID--MEDULLARY CA OF THE THYROID. ... Ectodermal Neoplasms. Ectodermal Neoplasms. ECTODERMAL-NEOPLASMS NOS. SALIVARY GLAND TUMORS ARE ALL ECTODERMAL. ADNEXAL TUMORS ...
Connect with our community and explore comprehensive information on Benign Neoplasm of Eye. Shared experiences for a healthier ... Iris nevus - Leiomyoma of iris - Leiomyoma of ciliary body - Oculodermal melanocytosis - Benign Neoplasm of Orbit - Benign ... Benign Neoplasm of Retina - Benign Neoplasm of Eye Not Elsewhere Classified - Benign Neoplasm of Lacrimal Duct - Benign ... Benign eye neoplasm symptoms may include redness, eye bulging, irritation, burning, itching, swelling or vision changes. ...
... and eventually to neoplasms, such as cervical intraepithelial neoplasias, squamous cell cancers, anal squamous cell cancers, or ... Wild Iris Medical Education. Retrieved from https://wildirismedicaleducation.com. Syrjänen S, Rintala M, Sarkola M, Willberg J ...
De Stefano, V., Qi, X., Betti, S., & Rossi, E. (2016). Splanchnic vein thrombosis and myeloproliferative neoplasms: molecular- ... Philadelphia-negative myeloproliferative neoplasms (MPNS) are the leading systemic cause of non-cirrhotic and non-malignant SVT ... Philadelphia-negative myeloproliferative neoplasms (MPNS) are the leading systemic cause of non-cirrhotic and non-malignant SVT ... De Stefano, V, Qi, X, Betti, S & Rossi, E 2016, Splanchnic vein thrombosis and myeloproliferative neoplasms: molecular-driven ...
Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms ... Schmitt Iris, Drees Philipp, Mirsch Johanna, Grabow Desiree, Schmidberger Heinz, Binder Harald, Hess Moritz, Galetzka Danuta, ... and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms. ...
Choroid Neoplasms, Brachytherapy, Eye Enucleation, Iris Neoplasms, Ciliary Body, Conjunctiva, Conjunctival Neoplasms, Anatomy, ... Head and Neck Neoplasms, Breast Neoplasms, Nevi and Melanomas, Skin Neoplasms, Central Nervous System Neoplasms, ... Neoplasms, Head and Neck Neoplasms, Mouth Neoplasms, Surgical Procedures, Operative, General Surgery, Salivary Gland Neoplasms ... Breast Neoplasms, Prostatic Neoplasms, Lung Neoplasms, Colonic Neoplasms, Social Conditions, 50334, Carcinoma, Non-Small-Cell ...
Iris Neoplasms Magnetic Resonance Imaging Plasmacytoma Ruthenium Radioisotopes Substances Ruthenium Radioisotopes PMID: ... Iris plasmacytoma is rare and should prompt systemic evaluation to rule out multiple myeloma. Solitary iris plasmacytoma can be ... Solitary Iris Plasmacytoma With Anterior Chamber Crystalline Deposits. Andrew W Stacey, Alenka Lavric, Caroline Thaung, Samreen ... An iris biopsy showed an infiltrate of plasma cells. Immunohistochemistry for kappa and lambda light chains demonstrated lambda ...
IRIS DISEASES] 86. ԾՆՈՏԱ-ԴԻՄԱՅԻՆ ԴԻԶՕՍՏՈԶ [MANDIBULOFACIAL DYSOSTOSIS] 37. ԾԻԱԾԱՆԻ ՆՈՐԱԳՈՅԱՑՈՒԹՅՈՒՆՆԵՐ [IRIS NEOPLASMS] 87. ... PERIPHERAL NERVE NEOPLASMS] 64. ԾՆՆԴԱԲԵՐԱԿԱՆ ՎՆԱՍՎԱԾՔՆԵՐ [BRITH INJURIES] 15. ԾԱՆՐ ՇՂԹԱՆԵՐԻ ՀԻՎԱՆԴՈՒԹՅՈՒՆ [HEAVY CHAIN DISEASE ...
Iris 15% * Brain Neoplasms 13% * Cluster Analysis 12% * Magnetic Resonance Imaging 9% ...
35%), other malignant neoplasms such as colorectal cancer which is one of the most frequent intraabdominal cancers in women ... Iris Publishers, LLC. 315 Montgomery Street 10th Floor, Suite #900 San Francisco, CA 94104, USA +1-628-201-9788. Fax - +1-415- ... Iris Publishers LLC is licensed under a Creative Commons Attribution 4.0 International License. Based on a work at www. ... 2018 Iris Publishers LLC, All rights reserved. No part of this content may be reproduced or transmitted in any form or by any ...
Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving the ... N2 - Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving ... AB - Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving ... abstract = "Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors ...
Application of cocaine drops will dilate the unaffected iris but not the Horner iris. AC will have the opposite effect; the ... and neurologic neoplasms (9%) were the next leading causes. ... Horner iris will dilate, whereas the unaffected iris will not. ... Cocaine drops block the reuptake of NE at the sympathetic nerve terminal to the iris dilator muscle, and AC acts as an agonist ... to the receptors of the iris dilator muscle, which are hypersensitive in Horner syndrome due to denervation. ...
Eight facility workers had iris nevi, which was not observed in 1978. In the control population, iris nevi not previously ... Follow-up Examinations for Occular Neoplasms and Pigmented Ocular Lesions, at the Dupont, West Virginia Plant. ... The prevalence of participants with conjunctival nevi, iris nevi, and chordal nevi amounted to 0.9 and and nonindustrial ... were ophthalmologically surveyed first in 1978 and again in 1979 in a follow-up study to identify cases of ocular neoplasms and ...
https://extranet.who.int/iris/restricted/handle/10665/53694?locale-attribute=en&show=full ... Liver Neoplasms Entry term(s). Hepatic Neoplasm Hepatic Neoplasms Liver Neoplasm Neoplasm, Hepatic Neoplasm, Liver Neoplasms ... Liver Neoplasm. Neoplasm, Hepatic. Neoplasm, Liver. Neoplasms, Hepatic. Neoplasms, Liver. ... Cancer of Liver Entry term(s). ... Neoplasms, Liver; Neoplasms, Hepatic; Hepatic Neoplasms; Cancer of the ... Brain Neoplasms *Hemangioma *Liver Neoplasms. ...
Choroid Neoplasms, Brachytherapy, Eye Enucleation, Iris Neoplasms, Ciliary Body, Conjunctiva, Conjunctival Neoplasms, Anatomy, ... Head and Neck Neoplasms, Breast Neoplasms, Nevi and Melanomas, Skin Neoplasms, Lung Neoplasms, Central Nervous System Neoplasms ... Neoplasms, Medical Oncology, Oncology Service, Hospital, Lung, Lung Neoplasms, Carcinoma, Small Cell, Carcinoma, Non-Small-Cell ... Eye Neoplasms, Pathological Conditions, Signs and Symptoms, Epidemiology, Neoplasms, Lymph Nodes, Lymph Node Excision, Sentinel ...
... lung neoplasms; male; middle aged; neoplasm staging; predictive value of tests; retrospective studies; tomography, x-ray ... I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione. ... La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi ... La simulazione può differire dallesito di uneventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, ...
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
  • Nodules had developed in the circumference and the lesion now imitated a malignant melanoma of the iris, which was also the diagnosis from a biopsy specimen with routine staining. (nih.gov)
  • Obviously, a tube or filter would be contraindicated in these situations and therefore the correct diagnosis of iris melanoma is imperative. (aao.org)
  • Diagnosis of benign eye neoplasms starts by an ophthalmologist examination. (alike.health)
  • Our objective is to provide a structured overview of the typical clinical symptoms and signs, the pathologic, ophthalmic, as well as hematologic work-up for diagnosis, treatment, and follow-up of iris lymphomas and offer a flowchart on how to diagnose and treat these tumors. (uni-luebeck.de)
  • Lymphocytic markers applied to the biopsy specimen and to the enucleated eye revealed a highly malignant T-cell lymphoma infiltrating the iris, ciliary body, anterior choroid, retina and the adjacent vitreous body. (nih.gov)
  • There are several melanocytic neoplasms that can occur in the uveal tract (iris, ciliary body, and choroid). (entokey.com)
  • An infiltrative mass of the iris and ciliary body was found that extended into the anterior, posterior, and vitreal chambers. (bvsalud.org)
  • A case is presented of an intraocular T-cell lymphoma mimicking a ring melanoma of the iris and being the first manifestation of systemic disease. (nih.gov)
  • Iris melanoma is the most common primary neoplasm of the iris and account for approximately 5% of all uveal melanomas . (aao.org)
  • There are several clinical variations including circumscribed, diffuse, and tapioca iris melanoma. (aao.org)
  • Tapioca melanoma is a name introduced by Reese and associates to describe a variant of iris melanoma with multiple amelanotic nodules on the surface giving the appearance of tapioca pudding. (aao.org)
  • Figure 3A: Ultrasound image of iris melanoma: A-scan showing low internal reflectivity. (aao.org)
  • 6] Case reports have described AN associated with hematologic malignancies, including acute myeloid leukemia, and even benign gastrointestinal neoplasms. (medscape.com)
  • Active and retired workers at the duPont Belle chemicals facility in West Virginia were ophthalmologically surveyed first in 1978 and again in 1979 in a follow-up study to identify cases of ocular neoplasms and determine the prevalence of ocular pigmented lesions. (cdc.gov)
  • Most iris melanomas are composed of spindle cells (Fig. 1B, C) and are, therefore, regarded as low-grade tumors. (aao.org)
  • Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving the iris. (uni-luebeck.de)
  • It is important to remember iris nevi can also be associated with ectropion uveae so the presence of this does not imply malignancy. (aao.org)
  • The prevalence of participants with conjunctival nevi, iris nevi, and chordal nevi amounted to 0.9 and and nonindustrial workers, respectively. (cdc.gov)
  • Eight facility workers had iris nevi, which was not observed in 1978. (cdc.gov)
  • In the control population, iris nevi not previously described were found in five patients. (cdc.gov)
  • When clinical-pathological characteristics are compared between primary CE and synchronous epithelial ovarian cancer (EOC) [10], the incidence of endometriosis is higher in patients with EC than in EOC (100% vs. 35%), other malignant neoplasms such as colorectal cancer which is one of the most frequent intraabdominal cancers in women that could exist in association with endometriosis. (irispublishers.com)
  • [ 11 , 12 ] Spontaneous hyphemas due to iris chafing can be seen with anterior chamber intraocular lenses as in uveitis-glaucoma-hyphema (UGH) syndrome or poorly placed posterior chamber intraocular lenses. (medscape.com)
  • In addition to a circumscribed or diffuse iris mass, heterochromia, chronic uveitis, glaucoma, or spontaneous hyphema may occur. (aao.org)
  • Iris melanomas can cause secondary glaucoma from direct extension into the trabecular meshwork, neovascular glaucoma , or inflammatory posterior synechia. (aao.org)
  • The latter procedure is reserved for a diffuse involvement of the iris and angle structures or the development of complications like glaucoma that are not amenable to non-invasive methods. (aao.org)
  • This examination is performed in case of suspected glaucoma, vascular neoplasms in the eye or a tumor on the iris. (proeyes.at)
  • Iris lesions are the most common intraocular manifestation of the disease (68%) [2] and virtually always unilateral. (eyewiki.org)
  • A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma. (unibo.it)
  • Philadelphia-negative myeloproliferative neoplasms (MPNS) are the leading systemic cause of non-cirrhotic and non-malignant SVT and are diagnosed in 40 % of BCS patients and one-third of EHPVO patients. (unicatt.it)
  • Association of JAK2-V617F Mutations Detected by Solid Tumor Sequencing With Coexistent Myeloproliferative Neoplasms. (cdc.gov)
  • It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
  • Most iris melanomas are asymptomatic and thus diagnosed at an ophthalmic routine examination. (aao.org)
  • Neurofibromatosis 1 is an autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms. (medlink.com)
  • The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. (bvsalud.org)
  • We summarize previously published data and make recommendations for work-up strategies for cases of suspected iris lymphoma. (uni-luebeck.de)
  • Follow-up Examinations for Occular Neoplasms and Pigmented Ocular Lesions, at the Dupont, West Virginia Plant. (cdc.gov)
  • [1] Iris lesions may be localized, yellowish, vascularized elevated masses or appear as a diffuse thin layer on the iris surface, causing heterochromia (Figure 2). (eyewiki.org)
  • Although there is no gender predilection, iris melanomas occur more frequently in Caucasians with a light colored iris versus non-Caucasians. (aao.org)
  • Clinically, circumscribed (Fig. 1A) and diffuse (Fig. 2A) iris melanomas can be distinguished. (aao.org)
  • Circumscribed iris melanomas appear as a variably pigmented well-defined mass in the iris stroma and is more commonly found in the inferior half of the iris. (aao.org)
  • Diffuse iris melanomas present with progressive iris discoloration with disappearance of iris crypts and accumulation of pigment in the anterior chamber. (aao.org)
  • More aggressive iris melanomas (Fig. 2B) exhibit a varying amount of epithelioid cells. (aao.org)
  • The treatment strategy of iris melanomas depends on the clinical impression and behavior. (aao.org)
  • Agrupación de tres afecciones estrechamente vinculadas: iris nevus o Síndrome de Cogan-Reese, Síndrome de Chandler y atrofia del iris esencial (progresiva). (bvsalud.org)
  • A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. (bvsalud.org)
  • Acceptance of the agent gave sufferers the potential to attain a normal life time although guidelines presently recommend therapy to become continuing indefinitely [16 201 Imatinib was set up as the typical of look after Dihydroartemisinin sufferers with CP-CML predicated on the outcomes from the pivotal International Randomized Research of Interferon and STI571 (IRIS) trial which included 1 106 patients newly. (healthcarecoremeasures.com)
  • In the IRIS (International Randomized Study of Interferon and STI571) study, imatinib produced a higher rate of complete cytogenetic response (CCyR) and major cytogenetic response (MCyR) compared with interferon alpha and cytarabinenal. (medscape.com)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • Figure 2: Nodular iris juvenile xanthogranuloma in a 20-month-old girl (used with permission from AAO). (eyewiki.org)
  • Solitary Iris Plasmacytoma With Anterior Chamber Crystalline Deposits. (illumina.com)