Iris Neoplasms
Iris
Iris Plant
Clitoris
Vulva
Encyclopedias as Topic
Bartholin's Glands
Factors associated with elevated intraocular pressure in eyes with iris melanoma. (1/30)
AIM: To identify clinical factors associated with secondary elevated intraocular pressure (IOP) in eyes with iris malignant melanoma METHODS: A retrospective case series of 169 consecutive patients with microscopically confirmed iris malignant melanoma. The main outcome measure was the presence of tumour induced secondary elevated IOP. Cox proportional regression models were used to calculate the relation of clinical features to elevated IOP. RESULTS: Of 169 patients with microscopically proved iris melanoma, 50 (30%) presented with tumour induced secondary elevated IOP. The mean pressure in those eyes with elevated IOP at diagnosis was 33 mm Hg (median 31 mm Hg, range 23-65 mm Hg). The tumour configuration was nodular in 23 (46%) and diffuse in 27 (54%) with a mean base dimension of 7.4 mm and thickness of 2.0 mm. Invasion of the angle structures by melanoma seeds was visible for a mean of 7 clock hours (median 7, range 0-12 clock hours). The mechanism of elevated IOP was judged to be outflow obstruction from tumour invasion into the trabecular meshwork. There were no cases of neovascular glaucoma. The tumour was ultimately managed with enucleation in 30 patients (60%), local resection (iridectomy, iridocyclectomy, or iridocyclogoniectomy) in 11 (22%), and plaque radiotherapy in five (10%). In four cases (8%), observation of cytologically low grade tumour was the patient's preference. Using multivariate analysis, the clinical factors at initial evaluation associated with tumour induced secondary elevated IOP from iris melanoma included increasing extent of tumour seeding in the anterior chamber angle (p=0.01) and poor visual acuity at presentation (p=0.02). CONCLUSIONS: Microscopically confirmed iris melanoma demonstrates tumour related elevated IOP in 30% cases at the time of presentation, usually secondary to tumour involvement of the trabecular meshwork obstructing aqueous outflow. Enucleation is necessary in the majority of these patients (60%) as opposed to those cases without elevated intraocular pressure (18%). (+info)Primary iris melanoma: diagnostic features and outcome of conservative surgical treatment. (2/30)
AIMS: To describe features influencing the management of primary iris melanoma and report the outcome of conservative surgical treatment of patients diagnosed with this condition in a tertiary referral academic setting over a 20 year period. METHODS: Retrospective non-comparative case series of consecutive patients diagnosed with iris melanoma from 1980-2000 using medical records from the University of Sydney Department of Ophthalmology and NSW Cancer Registry RESULTS: 51 cases were identified. The most common presentation was growth of a previously noted pigmented lesion. Initial management was either observation or local resection (two had enucleations) with iris reconstruction where possible (23.8%). The mean follow up was 8.7 years (range 1-17 years). Vision of 6/12 or better was maintained in the majority (78.6%) treated by local resection. Pupil reconstruction significantly reduced reported postoperative glare symptoms. Four patients had features suggestive of local recurrence and there was no documented metastatic disease or death from iris melanoma in this series. Histologically, the majority were spindle B cell melanomas. Clinical features including prominent tumour vascularity, rapid growth, and heterogeneous pigmentation were each significantly associated with an epithelioid cell component. Involvement of the iridocorneal angle was frequently associated with ciliary body invasion. CONCLUSIONS: Management decisions for iris melanoma will depend on the clinical features. Mixed or epithelioid histology is more likely in the presence of two or more of the features of malignancy and may justify earlier intervention. When treatment is undertaken, local resection achieves long term tumour clearance with an acceptable morbidity. In resecting iris melanoma, careful assessment for iridocorneal angle involvement is important in treatment planning. Iris reconstruction has a useful role in reducing postoperative photophobia. (+info)Uveal melanomas express vascular endothelial growth factor and basic fibroblast growth factor and support endothelial cell growth. (3/30)
BACKGROUND: Tumour microvascularity is a significant determinant of prognosis for a large number of different tumours, including uveal melanoma. The development of blood vessels within these and other tumours is partly controlled by soluble pro-angiogenic cytokines, of which basic fibroblast growth factor (bFGF) and vascular endothelial growth factor-A (VEGF) are the best described. METHODS: Because VEGF has been inconsistently found within uveal melanomas and bFGF is described as an autocrine growth factor in cutaneous melanoma, the authors looked at the expression of these cytokines in uveal melanomas using immunohistochemistry and reverse transcriptase polymerase chain reaction (RT-PCR). The cross talk between uveal melanoma cells and endothelial cells was then assessed in an in vitro co-culture model. RESULTS: While most tumour cells expressed bFGF at the protein level by immunohistochemistry (89%), relatively few (22%) expressed VEGF, and this was of limited extent. All 20 tumours tested by RT-PCR contained mRNA for both bFGF and VEGF. Co-culture experiments using an ATP based bioassay showed that uveal melanomas could support the growth of a rat brain endothelial cell line (GPNT) and human umbilical vein endothelial cells (HUVEC), and that this could be modulated by cytokines and anti-cytokine antibodies. CONCLUSION: These results suggest that angiogenesis within uveal melanoma may be the result of a complex interplay between endothelial and tumour cells, and that bFGF and VEGF could play a part. (+info)Lack of detection of feline leukemia and feline sarcoma viruses in diffuse iris melanomas of cats by immunohistochemistry and polymerase chain reaction. (4/30)
Diffuse iris melanoma was confirmed by light-microscopic examination in 10 formalin-fixed, paraffin-embedded globes from 10 cats. To determine if feline leukemia virus or a replication defective feline leukemia virus, feline sarcoma virus, was present in these anterior uveal melanomas, immunohistochemistry and polymerase chain reaction for feline leukemia virus were utilized. Immunohistochemical staining for feline leukemia virus glycoprotein 70 was performed on all 10 tumors using an avidin-biotin complex technique. The DNA was extracted from each specimen and a 166-base pair region of the feline leukemia virus long terminal repeat was targeted by polymerase chain reaction. Immunohistochemical staining for feline leukemia virus glycoprotein 70 and polymerase chain reaction amplification of a feline leukemia virus long terminal repeat region were negative in all cases. Feline leukemia virus/feline sarcoma virus was not detected in any neoplasms and therefore was unlikely to play a role in the tumorigenesis of these feline diffuse iris melanomas. (+info)Tumor necrosis factor alpha increases and alpha-melanocyte-stimulating hormone reduces uveal melanoma invasion through fibronectin. (5/30)
Iris melanomas are less likely to metastasize than posterior compartment melanomas. The anterior chamber of the eye is an immunosuppressed microenvironment where a wide range of immunosuppressive factors in aqueous humor contribute to the immune privilege. One such factor is alpha-melanocyte-stimulating hormone, a potent anti-inflammatory neuropeptide that exhibits efficacy in many studies of acute and chronic inflammation. The aim of this study was to investigate whether the different metastatic behavior of iris melanomas versus posterior compartment melanomas might be explained by the differing immunosuppressive/anti-inflammatory environments of these tumors in vivo. To investigate this hypothesis, we studied the effect of human aqueous and vitreous fluids, of the proinflammatory cytokine tumor necrosis factor alpha, and of the anti-inflammatory peptides alpha-melanocyte-stimulating hormone and melanocyte-stimulating hormone 11-13 (KP-D-V) on the invasion of three human uveal melanoma cell lines through human fibronectin. Fresh aqueous humor samples significantly decreased the invasion in two out of three uveal melanoma cell lines. In contrast, vitreous humor did not reduce invasion. Tumor necrosis factor alpha significantly increased the invasiveness of uveal melanoma cell lines by approximately 50%-80% over 20 h. Full-length alpha-melanocyte-stimulating hormone, at concentrations present in the aqueous humor (10-9 M), as well as melanocyte-stimulating hormone 11-13 (KP-D-V) reduced the invasion of cells through human fibronectin by 45%-50% and also protected uveal melanoma cells from the pro-invasive actions of tumor necrosis factor alpha. These data are consistent with inflammation playing a major role in affecting the metastatic ability of uveal melanomas. Thus, ocular microenvironments that differ in their immunosuppressive/anti-inflammatory properties may influence the invasiveness of developing tumors. (+info)Congenital adenoma of the iris and ciliary body: light and electron microscopic observations. (6/30)
A 23-year-old man had a lesion in the right inferior iris which appeared to have enlarged since it was first seen when the patient was aged 5 years. The lesion was excised by a partial iridocyclectomy. Histopathologically the neoplasm was composed of both pigmented and non-pigmented cells. Pseudoacini, containing acid mucopolysaccharides, were present throughout the tumour matrix. Electron microscopically the non-pigmented cells were found to possess a convoluted plasmalemma, abundant rough endoplasmic reticulum, and numerous desmosomes and gap junctions. The pigmented cells contained large, round, mature melanosomes, occasional premelanosomes, and desmosomes, which resembled the posterior pigment epithelium of the iris. The intercellular matrix contained fine collagen fibrils resembling vitreous. We believe that this neoplasm represents a congenital adenoma of the ciliary body and iris. (+info)Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. (7/30)
AIM: To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. METHODS: Cross sectional study of 65 patients with posterior uveal melanoma and 218 controls. Iris colour, iris freckles, iris naevi, and choroidal naevi were recorded for each eye of each patient. RESULTS: Iris freckles were present in 40 (61.5%) patients with melanoma and 135 (61.9%) controls (p = 0.494). Iris naevi were present in four (6.2%) patients with melanoma and nine (4.1%) controls (p = 0.955). Choroidal naevi were present in 12 (18.5%) patients with melanoma and 38 (17.4%) controls (p = 0.815). CONCLUSION: This study did not detect an association between posterior uveal melanoma and iris freckles, iris naevi, or choroidal naevi. (+info)The Finger iridectomy technique: small incision biopsy of anterior segment tumours. (8/30)
AIMS: To develop a minimally invasive, maximally effective method to biopsy anterior segment tumours. METHODS: A 25 gauge aspiration cutter (vitrector) was used to biopsy anterior segment tumours. The probe was introduced under sodium hyaluronate 1% and through a 1 mm incision. Aspiration (600 mm Hg) cutting (300 cpm) was performed to obtain specimens for cytology and histopathology. RESULTS: Diagnostic material was obtained in nine of 10 (90%) cases. Diagnoses included iris naevus, iris stroma, malignant melanoma, melanocytoma, epithelial inclusion cyst, and sarcoid granuloma. All corneal wounds were self sealing. One patient developed a transient postoperative increase in intraocular pressure. Within the follow up of this study, no patients suffered intraocular haemorrhage, infection, cataract or vision loss. CONCLUSION: The Finger iridectomy technique was a minimally invasive and very effective biopsy technique. Aspiration cutting yielded relatively large pieces of tissue (and cells) used for cytopathological and histopathological evaluation. Small incision surgery allowed for rapid rehabilitation and no significant complications. (+info)Iris neoplasms refer to abnormal growths or tumors that develop in the iris, which is the colored part of the eye. These neoplasms can be benign (non-cancerous) or malignant (cancerous). Benign iris neoplasms are typically slow-growing and do not spread to other parts of the body. Malignant iris neoplasms, on the other hand, can grow quickly and may spread to other parts of the eye or nearby structures, such as the ciliary body or choroid.
Iris neoplasms can cause various symptoms, including changes in the appearance of the eye, such as a visible mass or discoloration, pain, redness, light sensitivity, blurred vision, or changes in the size or shape of the pupil. The diagnosis of iris neoplasms typically involves a comprehensive eye examination, including a visual acuity test, refraction, slit-lamp examination, and sometimes imaging tests such as ultrasound or optical coherence tomography (OCT).
Treatment options for iris neoplasms depend on the type, size, location, and severity of the tumor. Small, benign iris neoplasms may not require treatment and can be monitored over time. Larger or malignant iris neoplasms may require surgical removal, radiation therapy, or other treatments to prevent complications or spread to other parts of the eye or body. It is essential to seek medical attention promptly if you experience any symptoms of iris neoplasms or notice any changes in your vision or the appearance of your eyes.
In medical terms, the iris refers to the colored portion of the eye that surrounds the pupil. It is a circular structure composed of thin, contractile muscle fibers (radial and circumferential) arranged in a regular pattern. These muscles are controlled by the autonomic nervous system and can adjust the size of the pupil in response to changes in light intensity or emotional arousal. By constricting or dilating the iris, the amount of light entering the eye can be regulated, which helps maintain optimal visual acuity under various lighting conditions.
The color of the iris is determined by the concentration and distribution of melanin pigments within the iris stroma. The iris also contains blood vessels, nerves, and connective tissue that support its structure and function. Anatomically, the iris is continuous with the ciliary body and the choroid, forming part of the uveal tract in the eye.
Iris diseases refer to a variety of conditions that affect the iris, which is the colored part of the eye that regulates the amount of light reaching the retina by adjusting the size of the pupil. Some common iris diseases include:
1. Iritis: This is an inflammation of the iris and the adjacent tissues in the eye. It can cause pain, redness, photophobia (sensitivity to light), and blurred vision.
2. Aniridia: A congenital condition characterized by the absence or underdevelopment of the iris. This can lead to decreased visual acuity, sensitivity to light, and an increased risk of glaucoma.
3. Iris cysts: These are fluid-filled sacs that form on the iris. They are usually benign but can cause vision problems if they grow too large or interfere with the function of the eye.
4. Iris melanoma: A rare type of eye cancer that develops in the pigmented cells of the iris. It can cause symptoms such as blurred vision, floaters, and changes in the appearance of the iris.
5. Iridocorneal endothelial syndrome (ICE): A group of rare eye conditions that affect the cornea and the iris. They are characterized by the growth of abnormal tissue on the back surface of the cornea and can lead to vision loss.
It is important to seek medical attention if you experience any symptoms of iris diseases, as early diagnosis and treatment can help prevent complications and preserve your vision.
I am not aware of a specific medical definition for "Iris Plant." The term "iris" in a medical context usually refers to the colored part of the eye that regulates the size of the pupil and controls the amount of light that enters the eye.
However, the "Iris Plant" (Iris spp.) is a type of perennial flowering plant that belongs to the family Iridaceae. It is native to temperate regions of the Northern Hemisphere, although there are also some species found in tropical and subtropical areas. The iris plant has long, sword-shaped leaves and showy flowers that come in various colors, including blue, purple, yellow, white, and red.
If you have any further questions or need information related to a medical topic, please let me know!
Vulvar neoplasms refer to abnormal growths or tumors in the vulvar region, which is the exterior female genital area including the mons pubis, labia majora, labia minora, clitoris, and the vaginal vestibule. These neoplasms can be benign (non-cancerous) or malignant (cancerous).
Benign vulvar neoplasms may include conditions such as vulvar cysts, fibromas, lipomas, or condylomas (genital warts). They are typically slow-growing and less likely to spread or invade surrounding tissues.
Malignant vulvar neoplasms, on the other hand, are cancers that can invade nearby tissues and potentially metastasize (spread) to distant parts of the body. The most common types of malignant vulvar neoplasms are squamous cell carcinoma, vulvar melanoma, and adenocarcinoma.
Early detection and treatment of vulvar neoplasms are essential for improving prognosis and reducing the risk of complications or recurrence. Regular gynecological examinations, self-examinations, and prompt attention to any unusual symptoms or changes in the vulvar area can help ensure timely diagnosis and management.
The clitoris is an important female sex organ that is primarily responsible for sexual arousal and pleasure. It is a small, highly sensitive piece of tissue located at the front of the vulva, where the labia minora meet. The clitoris is made up of two parts: the visible part, known as the glans clitoris, and the hidden part, called the corpora cavernosa and crura.
The glans clitoris is a small knob-like structure that is covered by a hood, or prepuce, and is located at the top of the vulva. It contains a high concentration of nerve endings, making it highly sensitive to touch and stimulation. The corpora cavernosa and crura are the internal parts of the clitoris, which are made up of sponge-like erectile tissue that becomes engorged with blood during sexual arousal, leading to clitoral erection.
The clitoris plays a crucial role in female sexual response and pleasure. During sexual arousal, the clitoris swells and becomes more sensitive to touch, which can lead to orgasm. The clitoris is also an important source of sexual pleasure during masturbation and partnered sexual activity. Despite its importance in female sexuality, the clitoris has historically been overlooked or stigmatized in many cultures, leading to a lack of understanding and education about this vital organ.
Vulvar diseases refer to a range of medical conditions that affect the vulva, which is the external female genital area including the mons pubis, labia majora and minora, clitoris, and the vaginal opening. These conditions can cause various symptoms such as itching, burning, pain, soreness, irritation, or abnormal growths or lesions. Some common vulvar diseases include:
1. Vulvitis: inflammation of the vulva that can be caused by infection, allergies, or irritants.
2. Lichen sclerosus: a chronic skin condition that causes thin, white patches on the vulva.
3. Lichen planus: an inflammatory condition that affects the skin and mucous membranes, including the vulva.
4. Vulvar cancer: a rare type of cancer that develops in the tissues of the vulva.
5. Genital warts: caused by human papillomavirus (HPV) infection, these are small growths or bumps on the vulva.
6. Pudendal neuralgia: a nerve condition that causes pain in the vulvar area.
7. Vestibulodynia: pain or discomfort in the vestibule, the area surrounding the vaginal opening.
It is important to consult a healthcare professional if experiencing any symptoms related to vulvar diseases for proper diagnosis and treatment.
The vulva refers to the external female genital area. It includes the mons pubis (the pad of fatty tissue covered with skin and hair that's located on the front part of the pelvis), labia majora (the outer folds of skin that surround and protect the vaginal opening), labia minora (the inner folds of skin that surround the vaginal and urethral openings), clitoris (a small, sensitive organ located at the front of the vulva where the labia minora join), the external openings of the urethra (the tube that carries urine from the bladder out of the body) and vagina (the passageway leading to the cervix, which is the lower part of the uterus).
It's important to note that understanding the anatomy and terminology related to one's own body can help facilitate effective communication with healthcare providers, promote self-awareness, and support overall health and well-being.
An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.
Bartholin's glands are two small exocrine glands located in the female reproductive system. They are named after the Danish anatomist and surgeon Caspar Bartholin the Younger, who described them in 1677. These glands are about the size of a pea and are situated on either side of the vaginal opening, just inside the labia majora (the outer folds of skin surrounding the vaginal opening).
Bartholin's glands produce and secrete a mucus-like fluid that helps lubricate the vaginal opening, making sexual intercourse more comfortable. The fluid is released through small ducts that open into the vestibule, the area between the labia minora (the inner folds of skin surrounding the vaginal opening) and the hymen.
In some cases, Bartholin's glands can become blocked, causing a cyst or abscess to form. These conditions may require medical treatment, such as antibiotics, drainage, or surgical removal of the cyst or abscess.
Female genitalia refer to the reproductive and sexual organs located in the female pelvic region. They are primarily involved in reproduction, menstruation, and sexual activity. The external female genitalia, also known as the vulva, include the mons pubis, labia majora, labia minora, clitoris, and the external openings of the urethra and vagina. The internal female genitalia consist of the vagina, cervix, uterus, fallopian tubes, and ovaries. These structures work together to facilitate menstruation, fertilization, pregnancy, and childbirth.
Vulvar cancer
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Choroidal nevus
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Iris Neoplasms
Vulvar cancer - Wikipedia
Intraocular T-cell lymphoma mimicking a ring melanoma. First manifestation of systemic disease. Report of a case and survey of...
Hyphema: Overview, Elevated Intraocular Pressure, Secondary Hemorrhage
Retinal Dysplasia Mimicking Intraocular Tumor: MR Imaging Findings with Histopathologic Correlation | American Journal of...
The Ophthalmic Examination - WSAVA 2001 - VIN
Iris Melanoma - EyeWiki
Rapidly growing iris melanocytoma with secondary glaucoma in a 6-year-old child - Fingerprint - Icahn School of Medicine...
UEG - United European Gastroenterology
Neurofibromatosis 1 and intracranial neoplasms of childhood | MedLink Neurology
Results of search for 'ccl=su:{Neoplasms.}' › WHO HQ Library catalog
Iris Udasin - Fingerprint - Rutgers, The State University of New Jersey
Ectodermal Neoplasms | Midwest Sinus and Allergy
Understanding Benign Neoplasm of Eye: Causes, Symptoms, and Management
Sexually Transmitted Diseases CEU | Wild Iris Medical Education
Splanchnic vein thrombosis and myeloproliferative neoplasms: molecular-driven diagnosis and long-term treatment<...
Zentrum für Orthopädie und Unfallchirurgie | Forschung » Publikationen » Wissenschaftliche Publikationen
Portal Regional da BVS
Solitary Iris Plasmacytoma With Anterior Chamber Crystalline Deposits. - NextBio article
Armenian-English Medical - Terms starting with 'Ծ' - MEDINDEX.AM
Unsupervised Learning and Pattern Recognition of Biological Data Structures with Density Functional Theory and Machine Learning...
Endometriosis as a Risk Factor for Colorectal Cancer | Iris Publishers
Iris lymphoma-a systematic guide for diagnosis and treatment<...
When Anisocoria Signals A Bigger Problem | Children's Hospital of Philadelphia
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Liver neoplasms. Medical search
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Quantitative CT texture analysis in predicting PD-L1 expression in locally advanced or metastatic NSCLC patients
Humans1
- Substances that increase the risk of NEOPLASMS in humans or animals. (lookformedical.com)
Metastasis1
- Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. (lookformedical.com)
Diagnosis4
- Nodules had developed in the circumference and the lesion now imitated a malignant melanoma of the iris, which was also the diagnosis from a biopsy specimen with routine staining. (nih.gov)
- Obviously, a tube or filter would be contraindicated in these situations and therefore the correct diagnosis of iris melanoma is imperative. (aao.org)
- Diagnosis of benign eye neoplasms starts by an ophthalmologist examination. (alike.health)
- Our objective is to provide a structured overview of the typical clinical symptoms and signs, the pathologic, ophthalmic, as well as hematologic work-up for diagnosis, treatment, and follow-up of iris lymphomas and offer a flowchart on how to diagnose and treat these tumors. (uni-luebeck.de)
Ciliary3
- Lymphocytic markers applied to the biopsy specimen and to the enucleated eye revealed a highly malignant T-cell lymphoma infiltrating the iris, ciliary body, anterior choroid, retina and the adjacent vitreous body. (nih.gov)
- There are several melanocytic neoplasms that can occur in the uveal tract (iris, ciliary body, and choroid). (entokey.com)
- An infiltrative mass of the iris and ciliary body was found that extended into the anterior, posterior, and vitreal chambers. (bvsalud.org)
Melanoma5
- A case is presented of an intraocular T-cell lymphoma mimicking a ring melanoma of the iris and being the first manifestation of systemic disease. (nih.gov)
- Iris melanoma is the most common primary neoplasm of the iris and account for approximately 5% of all uveal melanomas . (aao.org)
- There are several clinical variations including circumscribed, diffuse, and tapioca iris melanoma. (aao.org)
- Tapioca melanoma is a name introduced by Reese and associates to describe a variant of iris melanoma with multiple amelanotic nodules on the surface giving the appearance of tapioca pudding. (aao.org)
- Figure 3A: Ultrasound image of iris melanoma: A-scan showing low internal reflectivity. (aao.org)
Benign1
- 6] Case reports have described AN associated with hematologic malignancies, including acute myeloid leukemia, and even benign gastrointestinal neoplasms. (medscape.com)
Ocular neoplasms1
- Active and retired workers at the duPont Belle chemicals facility in West Virginia were ophthalmologically surveyed first in 1978 and again in 1979 in a follow-up study to identify cases of ocular neoplasms and determine the prevalence of ocular pigmented lesions. (cdc.gov)
Malignant neoplasm1
- A primary malignant neoplasm of epithelial liver cells. (lookformedical.com)
Tumors2
- Most iris melanomas are composed of spindle cells (Fig. 1B, C) and are, therefore, regarded as low-grade tumors. (aao.org)
- Iris lymphomas are rare malignant neoplasms arising either as primary tumors in the iris or as secondary tumors involving the iris. (uni-luebeck.de)
Nevi4
- It is important to remember iris nevi can also be associated with ectropion uveae so the presence of this does not imply malignancy. (aao.org)
- The prevalence of participants with conjunctival nevi, iris nevi, and chordal nevi amounted to 0.9 and and nonindustrial workers, respectively. (cdc.gov)
- Eight facility workers had iris nevi, which was not observed in 1978. (cdc.gov)
- In the control population, iris nevi not previously described were found in five patients. (cdc.gov)
Primary1
- When clinical-pathological characteristics are compared between primary CE and synchronous epithelial ovarian cancer (EOC) [10], the incidence of endometriosis is higher in patients with EC than in EOC (100% vs. 35%), other malignant neoplasms such as colorectal cancer which is one of the most frequent intraabdominal cancers in women that could exist in association with endometriosis. (irispublishers.com)
Glaucoma5
- [ 11 , 12 ] Spontaneous hyphemas due to iris chafing can be seen with anterior chamber intraocular lenses as in uveitis-glaucoma-hyphema (UGH) syndrome or poorly placed posterior chamber intraocular lenses. (medscape.com)
- In addition to a circumscribed or diffuse iris mass, heterochromia, chronic uveitis, glaucoma, or spontaneous hyphema may occur. (aao.org)
- Iris melanomas can cause secondary glaucoma from direct extension into the trabecular meshwork, neovascular glaucoma , or inflammatory posterior synechia. (aao.org)
- The latter procedure is reserved for a diffuse involvement of the iris and angle structures or the development of complications like glaucoma that are not amenable to non-invasive methods. (aao.org)
- This examination is performed in case of suspected glaucoma, vascular neoplasms in the eye or a tumor on the iris. (proeyes.at)
Intraocular1
- Iris lesions are the most common intraocular manifestation of the disease (68%) [2] and virtually always unilateral. (eyewiki.org)
Multiple Myeloma1
- A phase II multicenter study of troxacitabine in relapsed or refractory lymphoproliferative neoplasms or multiple myeloma. (unibo.it)
Myeloproliferative2
- Philadelphia-negative myeloproliferative neoplasms (MPNS) are the leading systemic cause of non-cirrhotic and non-malignant SVT and are diagnosed in 40 % of BCS patients and one-third of EHPVO patients. (unicatt.it)
- Association of JAK2-V617F Mutations Detected by Solid Tumor Sequencing With Coexistent Myeloproliferative Neoplasms. (cdc.gov)
Epithelial1
- It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. (lookformedical.com)
Examination1
- Most iris melanomas are asymptomatic and thus diagnosed at an ophthalmic routine examination. (aao.org)
Intracranial1
- Neurofibromatosis 1 is an autosomally dominated inherited genetic condition that predisposes those involved to the development of intracranial neoplasms. (medlink.com)
Cornea1
- The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. (bvsalud.org)
Lymphoma1
- We summarize previously published data and make recommendations for work-up strategies for cases of suspected iris lymphoma. (uni-luebeck.de)
Lesions2
- Follow-up Examinations for Occular Neoplasms and Pigmented Ocular Lesions, at the Dupont, West Virginia Plant. (cdc.gov)
- [1] Iris lesions may be localized, yellowish, vascularized elevated masses or appear as a diffuse thin layer on the iris surface, causing heterochromia (Figure 2). (eyewiki.org)
Melanomas6
- Although there is no gender predilection, iris melanomas occur more frequently in Caucasians with a light colored iris versus non-Caucasians. (aao.org)
- Clinically, circumscribed (Fig. 1A) and diffuse (Fig. 2A) iris melanomas can be distinguished. (aao.org)
- Circumscribed iris melanomas appear as a variably pigmented well-defined mass in the iris stroma and is more commonly found in the inferior half of the iris. (aao.org)
- Diffuse iris melanomas present with progressive iris discoloration with disappearance of iris crypts and accumulation of pigment in the anterior chamber. (aao.org)
- More aggressive iris melanomas (Fig. 2B) exhibit a varying amount of epithelioid cells. (aao.org)
- The treatment strategy of iris melanomas depends on the clinical impression and behavior. (aao.org)
Nevus2
- Agrupación de tres afecciones estrechamente vinculadas: iris nevus o Síndrome de Cogan-Reese, Síndrome de Chandler y atrofia del iris esencial (progresiva). (bvsalud.org)
- A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. (bvsalud.org)
Interferon and STI5712
- Acceptance of the agent gave sufferers the potential to attain a normal life time although guidelines presently recommend therapy to become continuing indefinitely [16 201 Imatinib was set up as the typical of look after Dihydroartemisinin sufferers with CP-CML predicated on the outcomes from the pivotal International Randomized Research of Interferon and STI571 (IRIS) trial which included 1 106 patients newly. (healthcarecoremeasures.com)
- In the IRIS (International Randomized Study of Interferon and STI571) study, imatinib produced a higher rate of complete cytogenetic response (CCyR) and major cytogenetic response (MCyR) compared with interferon alpha and cytarabinenal. (medscape.com)
Metastases1
- Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
Juvenile xanthogranuloma1
- Figure 2: Nodular iris juvenile xanthogranuloma in a 20-month-old girl (used with permission from AAO). (eyewiki.org)
Anterior1
- Solitary Iris Plasmacytoma With Anterior Chamber Crystalline Deposits. (illumina.com)