Diseases of the lacrimal apparatus.
The tear-forming and tear-conducting system which includes the lacrimal glands, eyelid margins, conjunctival sac, and the tear drainage system.
A stack of flattened vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough ENDOPLASMIC RETICULUM and directing them to secretory vesicles, LYSOSOMES, or the CELL MEMBRANE. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus and fuse with the Golgi, lysosomes or cell membrane. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990)

Pterygium and its relationship to the dry eye in the Bantu. (1/165)

A comparative study was performed on two groups of Bantus in Johannesburg to see if there was any relationship between the "dry eye" and pterygia, but no correlation was found.  (+info)

Dacryolith formation around an eyelash retained in the lacrimal sac. (2/165)

A dacryolith was discovered in the lacrimal sac during a dacryocystorhinostomy for chronic dacryocystitis in which there was mucocele formation. Morphological examination confirmed the presence of an eyelash at the centre of the stone and electron microscopy demonstrated the presence of fungi (Candida sp.) in a matrix which was of markedly vairable morphology. The mechanism by which a hair enters the punctum and passes along the canaliculus may be attributed to the step-like pattern of ridges on the surface of a hair. The directional nature of these ridges dictates preferential movement towards the root end of the hair and prevents movements in the opposite direction.  (+info)

Does androgen insufficiency cause lacrimal gland inflammation and aqueous tear deficiency? (3/165)

PURPOSE: The current investigators have shown that androgen treatment suppresses inflammation and stimulates the function of lacrimal glands in mouse models of Sjogren's syndrome. Recently, others have hypothesized that androgen insufficiency induces an autoimmune process in lacrimal tissue, leading to inflammation, a Sjogren's syndrome-like pathology, and aqueous tear deficiency. The purpose of the present study was to test this hypothesis. METHODS: Lacrimal glands were obtained from adult testicular feminized (Tfm) and control mice; castrated rats, guinea pigs, and rabbits; and castrated rats without anterior or whole pituitary glands and were processed for histology and image analysis. Tear volumes were measured in mice, in patients taking antiandrogen medications, and in age-matched human control subjects. RESULTS: Tfm mice, which are completely resistant to classical androgen action, did not have increased lymphocyte infiltration in their lacrimal glands or decreased tear volumes. No inflammation was evident in lacrimal tissues of male or female rats, guinea pigs, or rabbits 12 to 31 days after castration, no inflammation existed in rat lacrimal glands 15 to 31 days after orchiectomy and pituitary removal, and no aqueous tear deficiency was apparent in patients receiving antiandrogen therapy. CONCLUSIONS: Androgen deficiency may promote the progression of Sjogren's syndrome and its associated lacrimal gland inflammation, meibomian gland dysfunction, and severe dry eye. However, androgen insufficiency alone does not cause lacrimal gland inflammation, a Sjogren's syndrome-like pathology in lacrimal tissue, or aqueous tear deficiency in nonautoimmune animals and humans.  (+info)

The puzzle of autism: an ophthalmologic contribution. (4/165)

PURPOSE: A previous study of 86 thalidomide-affected subjects with ophthalmic manifestations revealed the unexpected finding of autism in 4 of the 5 severely retarded individuals. The subjects had anomalies associated with an early gestational effect of thalidomide, including facial nerve palsy and incomitant strabismus. Because autism has been observed in a few cases of Mobius sequence (Mobius syndrome), a condition characterized by involvement of the sixth and seventh cranial nerves, the similarity to early thalidomide embryopathy suggested a relation between cranial nerve involvement and autism. The present study was undertaken to further evaluate the association of autism with patients manifesting findings of Mobius syndrome. METHODS: A prospective study of 25 Swedish patients with Mobius sequence was conducted. The patients had a complete multidisciplinary evaluation, including ophthalmologic and psychiatric examinations and standard testing for autism. Findings associated with autism were compared with the ocular and systemic anomalies of the 4 thalidomide-affected subjects. RESULTS: In the Mobius group 6 patients had autism, achieving the criteria for autism according to all the diagnostic manuals that were used. One patient showed autistic-like conditions meeting fewer numbers of the criteria. A few were too young to be meeting evaluated. Incomitant strabismus ranging from primary abduction defects alone to a horizontal gaze paresis pattern was noted in these patients, in addition to characteristic findings of seventh nerve paresis. Aberrant lacrimation was observed in many cases, especially often associated with autism. CONCLUSION: The common group of anomalies noted in both cases of thalidomide embryopathy and Mobius sequence suggests that brain-stem damage probably early in embryogenesis can sometimes be associated with autism.  (+info)

The 4A syndrome association with osteoporosis. (5/165)

4A syndrome is characterised by adrenocortical insufficiency, achalasia, alacrima, autonomic and other neurological abnormalities. We report an 18-year-old boy with 4 A syndrome and having all classical features of the disease including sensorimotor neuropathy. In addition, the patient had low aldosterone levels and signs of osteoporosis, which apparently developed without glucocorticoid replacement therapy. Although it is speculated that the lack of local growth factors, nutritional deficiency secondary to achalasia or receptor abnormalities regarding bone metabolism contribute to osteoporosis, its etiopathogenesis still needs to be clarified.  (+info)

Ductal cysts of the accessory lacrimal glands: CT findings. (6/165)

Benign ductal cysts of the accessory lacrimal glands are uncommon lesions of the orbit, arising from the glands of Wolfring and Krause. We report two patients with histopathologically proved cysts in whom CT scans revealed well-circumscribed extraconal cystic lesions adjacent to the globe, involving both eyelids. Radiologists should be aware of these rare lesions so as to include them in the differential diagnosis of orbital cysts.  (+info)

Prenatal diagnosis of dacryocystocele: a possible marker for syndromes. (7/165)

We present our experience of the sonographic prenatal diagnosis of dacryocystocele and review the literature. This lesion can be distinguished from a facial hemangioma, dermoid or anterior encephalocele by the ultrasound findings and Doppler flow studies. These conditions are separate entities and their associated diagnosis and prognosis are very different in each case. As dacryocystocele may be part of numerous syndromes, its prenatal visualization raises the rare possibility of associated anomalies.  (+info)

MR dacryocystography: comparison with dacryocystography and CT dacryocystography. (8/165)

BACKGROUND AND PURPOSE: Several techniques have been used to image the nasolacrimal system, providing functional (dacryoscintigraphy) or morphologic (dacryocystography, CT dacryocystography [CTD]) information. Using gadopentetate dimeglumine-diluted solution injected into the lacrimal canaliculus or instilled into the conjunctival sac, we compared the sensitivity of MR dacryocystography (MRD) with that of CTD. METHODS: Eleven healthy volunteers and 25 patients affected by primary epiphora (21 patients) or postsurgical recurrent epiphora (four patients) underwent MRD after the topical administration of contrast media or cannulation of the lacrimal canaliculus. The MR imaging findings were compared with irrigation and CTD data. All patients underwent surgical treatment (dacryocystorhinostomy), which served as a standard of reference for confirming the MRD findings. RESULTS: The topical administration of contrast-enhanced saline solution and the injection of contrast-enhanced saline solution after cannulation were always well tolerated. In healthy volunteers, outflow of contrast media was always revealed by MRD. Eight (32%) of 25 patients with epiphora had stenosis proximal to the lacrimal sac revealed by MRD, whereas 17 (68%) of 25 showed a dilated lacrimal sac and nasolacrimal duct stenosis, as confirmed by surgical findings. The findings of MRD after the topical administration of contrast medium and MRD after cannulation of the lacrimal canaliculus were comparable with irrigation or CTD data for all patients except one. CONCLUSION: In patients with epiphora, MR imaging performed after the topical administration of diluted contrast material can reveal stenosis of the lacrimal apparatus and can be added to the standard orbital imaging protocol when lacrimal system involvement is suspected.  (+info)

Lacrimal apparatus diseases refer to conditions that affect the structure and function of the lacrimal system, which is responsible for producing, storing, and draining tears. The lacrimal apparatus includes the lacrimal glands, lacrimal canaliculi, lacrimal sac, and nasolacrimal duct.

Diseases of the lacrimal apparatus can cause a range of symptoms, including watery eyes, redness, pain, swelling, and discharge. Some common conditions that affect the lacrimal apparatus include:

1. Dry eye syndrome: A condition in which the lacrimal glands do not produce enough tears or the tears are of poor quality, leading to dryness, irritation, and inflammation of the eyes.
2. Dacryocystitis: An infection of the lacrimal sac that can cause pain, swelling, redness, and discharge from the eye.
3. Nasolacrimal duct obstruction: A blockage in the nasolacrimal duct that can cause watery eyes, discharge, and recurrent infections.
4. Epiphora: Excessive tearing or watering of the eyes due to overflow of tears from the eye because of blocked tear ducts or increased production of tears.
5. Canaliculitis: An infection of the lacrimal canaliculi that can cause swelling, redness, and discharge from the eye.
6. Lacrimal gland tumors: Rare tumors that can affect the lacrimal glands and cause symptoms such as pain, swelling, and protrusion of the eyeball.

Treatment for lacrimal apparatus diseases depends on the specific condition and its severity. Treatment options may include medications, surgery, or a combination of both.

The lacrimal apparatus is a complex system in the eye that produces, stores, and drains tears. It consists of several components including:

1. Lacrimal glands: These are located in the upper outer part of the eyelid and produce tears to keep the eye surface moist and protected from external agents.
2. Tear ducts (lacrimal canaliculi): These are small tubes that drain tears from the surface of the eye into the lacrimal sac.
3. Lacrimal sac: This is a small pouch-like structure located in the inner part of the eyelid, which collects tears from the tear ducts and drains them into the nasolacrimal duct.
4. Nasolacrimal duct: This is a tube that runs from the lacrimal sac to the nose and drains tears into the nasal cavity.

The lacrimal apparatus helps maintain the health and comfort of the eye by keeping it lubricated, protecting it from infection, and removing any foreign particles or debris.

The Golgi apparatus, also known as the Golgi complex or simply the Golgi, is a membrane-bound organelle found in the cytoplasm of most eukaryotic cells. It plays a crucial role in the processing, sorting, and packaging of proteins and lipids for transport to their final destinations within the cell or for secretion outside the cell.

The Golgi apparatus consists of a series of flattened, disc-shaped sacs called cisternae, which are stacked together in a parallel arrangement. These stacks are often interconnected by tubular structures called tubules or vesicles. The Golgi apparatus has two main faces: the cis face, which is closest to the endoplasmic reticulum (ER) and receives proteins and lipids directly from the ER; and the trans face, which is responsible for sorting and dispatching these molecules to their final destinations.

The Golgi apparatus performs several essential functions in the cell:

1. Protein processing: After proteins are synthesized in the ER, they are transported to the cis face of the Golgi apparatus, where they undergo various post-translational modifications, such as glycosylation (the addition of sugar molecules) and sulfation. These modifications help determine the protein's final structure, function, and targeting.
2. Lipid modification: The Golgi apparatus also modifies lipids by adding or removing different functional groups, which can influence their properties and localization within the cell.
3. Protein sorting and packaging: Once proteins and lipids have been processed, they are sorted and packaged into vesicles at the trans face of the Golgi apparatus. These vesicles then transport their cargo to various destinations, such as lysosomes, plasma membrane, or extracellular space.
4. Intracellular transport: The Golgi apparatus serves as a central hub for intracellular trafficking, coordinating the movement of vesicles and other transport carriers between different organelles and cellular compartments.
5. Cell-cell communication: Some proteins that are processed and packaged in the Golgi apparatus are destined for secretion, playing crucial roles in cell-cell communication and maintaining tissue homeostasis.

In summary, the Golgi apparatus is a vital organelle involved in various cellular processes, including post-translational modification, sorting, packaging, and intracellular transport of proteins and lipids. Its proper functioning is essential for maintaining cellular homeostasis and overall organismal health.

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Khurana, AK (31 August 2015). "Diseases of lacrimal apparatus". Comprehensive ophthalmology (6th ed.). Jaypee, The Health ... The volume of tear in the eye depends on two factors, drainage through the lacrimal passages and evaporation. Factors like ... Evaporative dryness can also be seen in conditions like lagophthalmos, proptosis, Parkinsons disease, computer vision syndrome ...
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Nasolacrimal and Lacrimal Apparatus - Eye Diseases and Disorders". Merck Veterinary Manual. Archived from the original on 31 ... Guiliano EA (2013). "Diseases and surgery of the canine lacrimal secretory system". In Gelatt KH (ed.). Veterinary ... Nasolacrimal and Lacrimal Apparatus, The Merck Veterinary Manual. .mw-parser-output .navbox{box-sizing:border-box;border:1px ... lacrimal gland ablation, and sensory denervation.[14] In rare cases, it may be a symptom of collagen vascular diseases, ...
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  • Yet, infectious dacryoadenitis is thought to be caused by ascension of an inciting agent from the conjunctiva through the lacrimal ductules into the lacrimal gland. (medscape.com)
  • In addition to the lacrimal gland, lacrimal fluid is produced by special cells, which are located deep in the mucous membrane of the eye (conjunctiva) and are called goblet. (ucoz.com)
  • This includes conditions that affect the external structures of the eye, such as the eyelid, lacrimal apparatus, conjunctiva, and extraocular muscles. (lecturio.com)
  • Sections are included on all recognized neoplasms (and their variants) of the eye, lacrimal apparatus, and conjunctiva. (iarc.fr)
  • Drying and inflammation of the conjunctiva as a result of insufficient lacrimal secretion. (nih.gov)
  • Note 2:** Ocular adnexal lymphomas (OAL) originate in conjunctiva, eyelids, lacrimal gland, lacrimal drainage apparatus, and other orbital tissues surrounding the eye. (cancer.gov)
  • The volume of tear in the eye depends on two factors, drainage through the lacrimal passages and evaporation. (wikipedia.org)
  • The overall goal of this fellowship program is to provide advanced training in surgical and medical treatment of patients with diseases of the orbit, eyelid, ocular adnexae and lacrimal drainage apparatus and in reconstructive surgery of the ocular and periocular region, a discipline known as ophthalmic plastic and reconstructive surgery. (mdanderson.org)
  • Purpose: Orbital glands and drainage conduits are two distinct entities that constitute the lacrimal apparatus system, the malfunction of which leads to a range of ocular surface disorders. (bvsalud.org)
  • The study aims to investigate the lacrimal gland (LG) structural and functional changes upon the drainage system obstruction, thus, testing their function link. (bvsalud.org)
  • Being constantly exposed to the environmental stress, irritants and pathogens, the ocular surface - a specialized functional and anatomical unit composed of tear film, conjunctival and corneal epithelium, lacrimal glands, meibomian glands, and nasolacrimal drainage apparatus - serves as a crucial front-line defense of the eye. (irosacea.org)
  • Dimensions of the lacrimal drainage apparatus. (medscape.com)
  • The first part deals with conditions affecting the orbit, lids, and external eye, and the second focuses on diseases of structures within the eyeball, or globe. (britannica.com)
  • The orbit is the bony cavity in the skull that houses the globe of the eye (eyeball), the muscles that move the eye (the extraocular muscles), the lacrimal gland, and the blood vessels and nerves required to supply these structures. (britannica.com)
  • The lacrimal gland is located in the supratemporal orbit. (medscape.com)
  • Eyelid disorders may be associated with facial and orbital abnormalities, specific breeds, and adjunct skin diseases, as well as with many systemic diseases. (merckvetmanual.com)
  • Blepharitis refers to a family of inflammatory disease processes of the eyelid(s). (medscape.com)
  • Also provided is a pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating a subject suffering from an OID, uveitis, bacterial conjunctivitis, viral conjunctivitis, an inflammation of the orbital tissue, the lacrimal apparatus, the eyelid, the cornea, the retina or the optic pathway. (justia.com)
  • The oculoplastic surgery clinic offers evaluation and surgery for children and adults who have eyelid or eye brow abnormalities due to genetics, aging, disease, trauma or previous surgery. (uiowa.edu)
  • The authors review these signs and detail some common eyelid malignancies and treatment options for more advanced disease including novel targeted therapies. (touchophthalmology.com)
  • M.S. in Ophthalmology is a postgraduate course in medicine that involves an advanced study of the anatomy, physiology and diseases of the eye. (mycareersview.com)
  • Ophthalmology is the branch of medicine concerned with studying the structure, function, and diseases of the eye. (lecturio.com)
  • According to Gelatt's Veterinary Ophthalmology (1999), PRA is a term for a group of hereditary diseases that are characterized by a degeneration or dysplasia (abnormal development) of the photoreceptors at the back of the eye. (malamute-health.org)
  • Inflammatory enlargement of the lacrimal gland is much more common than lacrimal gland tumors . (medscape.com)
  • Herein, we described the clinicopathologic and radiologic features of biopsied lacrimal gland tumors. (bvsalud.org)
  • The superior wedge sign increased the likelihood of ACC compared with that of non-epithelial non-malignant lacrimal gland tumors (relative risk ratio = 13.44, p = 0.002). (bvsalud.org)
  • Although these patients present with a short symptom duration, urgent orbital imaging, tissue biopsy, and prompt treatment should be performed in patients with lacrimal gland tumors. (bvsalud.org)
  • Acquired cases typically occur in adults and are due to trauma, systemic diseases, or tumors. (lecturio.com)
  • Retinal Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
  • This graph shows the total number of publications written about "Retinal Diseases" by people in this website by year, and whether "Retinal Diseases" was a major or minor topic of these publications. (sdsu.edu)
  • Below are the most recent publications written about "Retinal Diseases" by people in Profiles. (sdsu.edu)
  • Nowadays in the world of medicine there are no methods of treatment for retinal diseases whose efficiency is comparable to that of the treatment with peptide bioregulators. (peptide-bioregulator.com)
  • Purpose Conjunctivodacryocystorhinostomy (CDCR) with the insertion of a Jones tube is a surgical procedure used to relieve epiphora caused by upper lacrimal system dysfunction from extensive proximal canalicular obstruction, canalicular stenosis, or canalicular flaccidity. (elsevierpure.com)
  • Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation. (harvard.edu)
  • Acute inflammation of the lacrimal gland is a rare and usually in children. (ucoz.com)
  • The histopathologic diagnoses were as follows: immunoglobulin G4-related disease (IgG4-RD) = 23, reactive lymphoid hyperplasia = 14, lymphoma = 14, nonspecific inflammation = 10, adenoid cystic carcinoma (ACC) = 9, and pleomorphic adenoma = 9. (bvsalud.org)
  • Dacryocystitis is the inflammation of the lacrimal sac due to nasolacrimal duct obstruction and the subsequent stasis of tears. (lecturio.com)
  • This application also provides a method for treating a subject suffering from an autoimmune disease-associated ocular inflammation comprising periodic ocular administration to the subject a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt, and an ocular pharmaceutical composition comprising laquinimod or a pharmaceutically acceptable salt thereof for use in treating an autoimmune disease-associated ocular inflammation. (justia.com)
  • Ocular Inflammatory Disease ("OID") is a general term for describing inflammation affecting one or more parts of the eye or surrounding eye tissue. (justia.com)
  • Inflammation of the lacrimal sac. (nih.gov)
  • Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. (harvard.edu)
  • The fluid secreted by the lacrimal glands. (bvsalud.org)
  • Rare heterozygous, deleterious variants in the FGF10 gene are known causes of the lacrimo-auriculo-dento-digital (LADD) syndrome and aplasia of lacrimal and salivary glands. (bvsalud.org)
  • Diseases involving the RETINA. (sdsu.edu)
  • Infections of the lacrimal system. (medscape.com)
  • Infections of lacrimal apparatus. (medscape.com)
  • Contribute to the emergence of blepharitis weakening the body's defenses during prolonged inflammatory diseases, chronic infections, chronic diseases of the gastrointestinal tract. (ucoz.com)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • It consists of the puncta, canaliculi, lacrimal sac, and nasolacrimal duct (see the image below). (medscape.com)
  • Dacryoadenitis and orbital myositis associated with lyme disease. (medscape.com)
  • An orbital computerized tomography scan showed an inhomogeneous mass in the right lacrimal gland region without bone involvement. (eyehospital.nl)
  • Canalikulitis - an inflammatory disease of the lacrimal canaliculus. (ucoz.com)
  • At its entrance to the lacrimal sac, the common canaliculus may dilate slightly, forming the sinus of Maier. (medscape.com)
  • The oblique entrance of the common canaliculus into the lacrimal sac forms the valve of Rosenmüller, which prevents retrograde reflux of fluid from the sac into the canaliculi. (medscape.com)
  • Glaucoma is a disease that occurs due to violations of hydrodynamics eye (intraocular fluid motion). (ucoz.com)
  • The frequency of the development of glaucoma was estimated to be 24,0% at stage IVa, 18,3% at stage IVb, and 9,2% at stage V. The clinical manifestations of glaucoma developing at stage IVa retinopathy of prematurity were especially well apparent in the patients with the congenital disease. (ruspoj.com)
  • The study has demonstrated that the overall success of the glaucoma treatment in the children presenting with stages IVa retinopathy of prematurity was 100% compared with 3.5% and 33.3% in those with stages IVb and V of the disease respectively. (ruspoj.com)
  • The glaucoma developing in the children with stages IV and V of retinopathy of prematurity is a refractory neovascular condition especially if it is associated with stages IVb and V of the primary disease. (ruspoj.com)
  • Disclosed is a method for treating an ocular inflammatory disease (OID), e.g., uveitis or conjunctivitis, comprising periodic administration of a therapeutically effective amount of laquinimod or a pharmaceutically acceptable salt thereof. (justia.com)
  • During a review of occupational exposures evaluated in the Special Immunizations Clinic at the U.S. Army Medical Research Institute of Infectious Diseases from 1989 to 2002, clinical evaluations of three laboratory workers with symptoms of conjunctivitis and localized swelling after exposure to SEB were identified. (cdc.gov)
  • Combined clinical and computed tomographic diagnosis of primary lacrimal fossa lesions. (medscape.com)
  • The disease process can result in damage to the lids with trichiasis, notching entropion, and ectropion. (medscape.com)
  • In it you will find what each of the ophthalmological terms is as well as the symptoms, pathology associated with each of the eye diseases and the most appropriate treatments. (areaoftalmologica.com)
  • Centers for Disease Control and Prevention. (cdc.gov)
  • The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. (cdc.gov)
  • Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. (cdc.gov)
  • The objective of the present work was to evaluate the possibilities for the prenatal ultrasonic examination with a view to diagnostics of developmental abnormalities in the organ of vision and its accessory apparatus. (ruspoj.com)
  • Later sections deal with injuries, ocular conditions associated with systemic disease , disorders of vision , methods of examining the eye, and devices for correcting visual defects. (britannica.com)
  • ICD-9-CM codes are used in medical billing and coding to describe diseases, injuries, symptoms and conditions. (icd9data.com)
  • The exact association between blepharitis and mortality is not known, but diseases with known mortality, such as systemic lupus erythematosus, may have blepharitis as part of their constellation of findings. (medscape.com)
  • The main function of the lacrimal gland - is the development of lacrimal fluid. (ucoz.com)
  • This article briefly describes the more common diseases of the eye and its associated structures, the methods used in examination and diagnosis , and the factors that determine treatment and prognosis. (britannica.com)
  • Multiparametric autoantibody analysis: a new paradigm for the diagnosis of connective tissue diseases. (harvard.edu)
  • [6] Another treatment that is sometimes suggested is lacrimal plugs that prevent tears from draining from the surface of the eye. (wikipedia.org)
  • In some cases, laboratory tests and imaging help determine abnormal structures and underlying disease. (lecturio.com)
  • Anterior view of the eye and surrounding structures including the lacrimal gland and tear ducts. (smartdraw.com)
  • In this review, the latest information regarding SP function and regulation in the human lacrimal system, the tear film and the ocular surface is summarized with regard to mucous epithelial integrity, rheological and antimicrobial properties of the tear film, tear outflow, certain disease states and possible therapeutic perspectives. (benthamopen.com)
  • eye disease , any of the diseases or disorders that affect the human eye . (britannica.com)
  • Previous studies indicate that pathogenic variants in FGF10 can cause childhood Interstitial Lung Disease (chILD) due to severe diffuse developmental disorders of the lung, but detailed reports on clinical presentation and follow-up of affected children are lacking. (bvsalud.org)
  • Association of Tear Osmolarity With Signs and Symptoms of Dry Eye Disease in the Dry Eye Assessment and Management (DREAM) Study. (harvard.edu)
  • Review of occupational exposures at the U.S. Army Medical Research Institute of Infectious Diseases from 1989 to 2002 showed that three laboratory workers had symptoms after ocular exposure to staphylococcal enterotoxin B (SEB). (cdc.gov)
  • Autoantibody status according to multiparametric assay accurately estimates connective tissue disease classification and identifies clinically relevant disease clusters. (harvard.edu)
  • An incompetent valve of Rosenmüller is observed clinically as air escaping from the lacrimal puncta when the individual blows his or her nose. (medscape.com)
  • Epithelium at the site of the future lacrimal sac is initially thicker, and canalization in this area is more extensive. (medscape.com)
  • Using repellents remains the best prophylactic measure for dogs against the increasing global threat of parasite-transmitted infectious diseases. (elanco.com)
  • This statement from Dr. Jean-Pierre Dedet, University of Montpellier, France , summarizes the discussions of 36 experts in natural sciences, veterinary and human medicine from Europe, North America and Asia during the 3rd International CVBD (companion vector-borne diseases) Symposium in Wiesbaden, Germany. (elanco.com)