A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.
Tumors or cancer of the UTERUS.
The smooth muscle coat of the uterus, which forms the main mass of the organ.
A relatively rare smooth muscle tumor found most frequently in the wall of the gastrointestinal tract, especially in the stomach. It is similar to other smooth muscle tumors but may become very large and hemorrhage and exhibit small cystic areas. Simple excision is almost always curative. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1354)
The state of having multiple leiomyomas throughout the body. (Stedman, 25th ed)
A benign tumor consisting of vascular and smooth muscle elements.
Surgical removal of a LEIOMYOMA of the UTERUS.
A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
Excision of the uterus.
A tumor composed of smooth muscle tissue, as opposed to leiomyoma, a tumor derived from smooth muscle.
Pregnadienes which have undergone ring contractions or are lacking carbon-18 or carbon-19.
The use of embolizing agents to block the arterial blood supply to parts or all of the UTERUS. The procedures are done to control bleeding or to cause destruction of uterine tissues.
Excessive uterine bleeding during MENSTRUATION.
Food that has been prepared and stored in a way to prevent spoilage.
A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
A group of proteins that covalently attach to selenium or SELENIUM-containing compounds.
Tumors or cancer of the INTESTINES.
Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed)
Tumor suppressor genes located in the 5q21 region on the long arm of human chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (ADENOMATOUS POLYPOSIS COLI) and GARDNER SYNDROME, as well as some sporadic colorectal cancers.
The nonstriated involuntary muscle tissue of blood vessels.

The ultrastructure of fibromyomatous myometrium and its relationship to infertility. (1/1060)

The aim of this study was to determine whether the ultrastructure of the non-neoplastic myometrial portion (host myometrium) of fibromyomatous uteri is normal or abnormal when compared to that of fibromyomata and normal myometria. Myometrial samples from 23 normal and 54 fibromyomatous uteri were examined at the ultrastructural level using standard electron microscopy techniques. Ultrastructural abnormalities of certain cellular organelles were noted in myocytes of fibromyomata but not in those of normal or host myometria. The sarcolemmal dense bands of host myometrial myocytes were of significantly greater length than those of normal myometria, but not significantly different to those of fibromyomata. Consequently, the numbers of caveolae in host myometria and fibromyomata are conceivably decreased in comparison to normal myometria. Host myometria can be, therefore, considered to be structurally abnormal. The specific structural abnormality noted may affect calcium metabolism in these tissues by causing a decrease in the cellular calcium extrusion mechanism and thus raising intracellular calcium concentrations. Such an abnormality may provide an answer, in terms of contraction abnormalities, for the unexplained infertility that occurs in a small percentage of symptomatic myomatous patients.  (+info)

Oxytocin and vasopressin receptors in human and uterine myomas during menstrual cycle and early pregnancy. (2/1060)

The purpose of this study was to determine the specificity and concentration of oxytocin (OT) and arginine vasopressin (AVP) binding sites in non-pregnant (NP) human and rhesus monkey endometrium, myometrium and fibromyomas, and to determine the cellular localization of OT receptor (OTR). Besides [3H]AVP, [125I]LVA, a specific VP1 receptor subtype antagonist, was used to determine vasopressin receptor (VPR) concentrations. Samples were obtained from 42 pre-menopausal and three pregnant women (5, 13 and 35 weeks gestation), and several NP and pregnant monkeys. Specificity of binding was assessed in competition experiments with unlabelled agonists and antagonists of known pharmacological potency. Cellular localization of OTR was determined by immunohistochemistry. In NP human uterine tissues, [3H]AVP was bound with higher affinity and greater binding capacity than [3H]OT, whereas in pregnant women and in NP and pregnant rhesus monkeys, uterine OT binding capacity was greater. OT and AVP binding sites discriminated very poorly between OT and AVP; [125I]LVA binding sites were more selective than [3H]AVP. Their ligand specificity and binding kinetics indicated the presence of two distinct populations of binding sites for OT and AVP in primate uterus. Endometrium of NP women and monkeys had low OTR and VPR concentrations. Myometrial and endometrial OTR and VPR were down-regulated in midcycle and in early human pregnancy, they were up-regulated in the secretory phase and second half of pregnancy. Immunoreactive OTR in NP uterus was localized in patches of myometrial muscle cells and small numbers of endometrial epithelial cells.  (+info)

Heparin inhibits proliferation of myometrial and leiomyomal smooth muscle cells through the induction of alpha-smooth muscle actin, calponin h1 and p27. (3/1060)

Mast cells are widely distributed in human tissues, including the human uterus. However, the function of mast cells in uterine smooth muscle has not been clearly established. Mast cells possess secretory granules containing such substances as heparin, serotonin, histamine and many cytokines. To help establish the role of mast cells in the human myometrium, the action of heparin was investigated using smooth muscle cells (SMC) from normal myometrium and from leiomyoma. The proliferation of cultured myometrial and leiomyomal SMC was inhibited by heparin treatment. Flow cytometric analysis showed that the population in the G1 phase of the cell cycle increased under heparin treatment. Western blotting analysis showed that markers of SMC differentiation such as alpha-smooth muscle actin (alpha-SMA), calponin h1 and cyclin-dependent kinase inhibitor p27 were induced by heparin, whereas cell-cycle-related gene products from the G1 phase of the cell cycle, such as cyclin E and cdk2, were not changed. Taken together, these results indicate that heparin inhibits the proliferation of myometrial and leiomyomal SMC through the induction of alpha-SMA, calponin h1 and p27. We suggest that heparin from mast cells may induce differentiation in uterine SMC and may influence tissue remodelling and reconstruction during physiological and pathophysiological events.  (+info)

Frequent loss of heterozygosity for chromosome 10 in uterine leiomyosarcoma in contrast to leiomyoma. (4/1060)

Distinction of malignant uterine leiomyosarcomas from benign leiomyomas by morphological criteria is not always possible. Leiomyosarcomas typically have complex cytogenetic abnormalities; in contrast, leiomyomas have simple or no cytogenetic abnormalities. To understand better the biological distinction(s) between these tumors, we analyzed two other potential markers of genomic instability, loss of heterozygosity (LOH) and microsatellite instability. We examined archival materials from 16 leiomyosarcomas and 13 benign leiomyomas by polymerase chain reaction for 26 microsatellite polymorphisms. Markers were selected based on previous reports of cytogenetic or molecular genetic abnormalities in leiomyosarcomas or leiomyomas and surveyed chromosomes 7, 9, 10, 11, 12, 14, 15, 16, 18, 21, and X. LOH for markers on chromosomes 15, 18, 21, and X was infrequent in leiomyosarcomas (1 of 6 tumors for each chromosome) and not observed for markers on chromosomes 7, 9, 11, 12, 14, or 16. Interestingly, 8 of 14 (57.2%) informative leiomyosarcomas had LOH for at least one marker on chromosome 10 and involved both chromosomal arms in 45.5% (5 of 11). In contrast to leiomyosarcomas, LOH for chromosome 10 was not found in 13 benign leiomyomas. Microsatellite instability was found infrequently in leiomyosarcomas and not detected in leiomyoma. Clinicopathological features (eg, atypia, necrosis, and clinical outcome) did not appear to correlate with LOH for chromosome 10. In contrast to other chromosomes studied, LOH on chromosome 10 was frequent in leiomyosarcomas and absent in benign leiomyomas.  (+info)

Treatment of uterine fibroid with triptorelin before hysterectomy. (5/1060)

OBJECTIVE: To study the effects of pretreatment with triptorelin on uterine fibroid before abdominal hysterectomy. METHODS: Fifteen premenopausal Chinese women with symptomatic uterine fibroids requiring hysterectomy were recruited in the study. All patients received monthly intramuscular injections of 3.75 mg triptorelin for three months prior to abdominal hysterectomy. RESULTS: There was significant reduction in the serum levels of oestradiol (68.6%), progesterone (95.6%) and luteinizing hormone (73.9%) and in uterine (45.0%) and fibroid (68.0%) volumes. The serum level of follicle-stimulating hormone and haemoglobin concentration were not significantly different. CONCLUSIONS: Shrinkage of uterine fibroids can be achieved in women who are rendered hypoestrogenic with monthly injections of triptorelin for three months. This treatment modality may be of value prior to hysterectomy or myomectomy especially when the fibroid is large.  (+info)

Tumor vascular pattern and blood flow impedance in the differential diagnosis of leiomyoma and adenomyosis by color Doppler sonography. (6/1060)

PURPOSE: Our objective was to evaluate the differences between leiomyoma and adenomyosis by color Doppler sonography with new criteria. METHODS: A total of 78 patients with symptomatic uterine nodularities who were sonographically suspected to have leiomyoma or adenomyosis without other coexisting pathologic conditions was enrolled in the study. All patients underwent transvaginal color Doppler sonography (7.0-MHz vaginal probe) or transabdominal color Doppler sonography (5.0 MHz) during the early follicular phase. The morphology, tumor vascular pattern, and blood flow impedance of the uterine tumors were measured. All of the patients underwent surgery and the pathologic reports were used as references. RESULTS: The mean age was not statistically significant in patients with adenomyosis versus leiomyoma (P > 0.05). The morphologic criteria for adenomyosis and leiomyoma by sonography detected 79% of adenomyosis and 84% of leiomyoma. Adenomyosis had 87% randomly scattered vessels or intratumoral signals and 88% of leiomyomas showed peripheral scattered vessels or outer feeding vessels. Eighty-two percent of adenomyosis had a pulsitility index (PI) of arteries within or around uterine tumors > 1.17 and 84% of leiomyomas had a PI < or = 1.17. The reliability test of tumor vascular pattern and blood flow impedance were better than that of using morphological criteria alone. CONCLUSIONS: With the aid of color Doppler sonography, tumor vascular pattern and blood flow impedance of the arteries within or around uterine tumors could more accurately diagnose adenomyosis and leiomyoma in addition to the morphologic criteria on transvaginal sonography.  (+info)

A case-control study to compare the variability of operating time in laparoscopic and open surgery. (7/1060)

The purpose of this study was to compare the variability of operating times for some of the most common gynaecological procedures performed laparoscopically and by open surgery. The case notes of 60 women randomly selected from a cohort of 600 who had undergone laparoscopic surgery for ectopic pregnancy, ovarian cysts, leiomyoma and hysterectomy were reviewed. These patients were matched with an equal number of women who had been treated by open surgery for similar indications. Additional matching criteria included age (+/-2 years), size of the lesion in cases of ovarian cysts and fibroids (+/-3 cm), the period of amenorrhoea in ectopic pregnancies, and uterine size and pelvic pathology in women undergoing hysterectomy. Comparison of laparoscopy and laparotomy showed that the mean procedure times were similar for the two routes of surgery, with the exception of hysterectomy which took significantly longer if done laparoscopically. The duration of laparoscopic surgery for ectopic pregnancy, ovarian cystectomy and hysterectomy was significantly less predictable than at laparotomy. These data indicate that with the exception of hysterectomy, the average operating time for laparoscopic procedures is comparable to that for laparotomy. In contrast, the variability of duration of laparoscopic surgery tends to be much greater than with laparotomy for all procedures considered.  (+info)

Estrogen receptors (ERalpha/ERbeta) in normal and pathological growth of the human myometrium: pregnancy and leiomyoma. (8/1060)

The distributions of the mRNAs for estrogen receptors (ERalpha and ERbeta) and their binding properties in myometria of pregnant and nonpregnant women and in leiomyoma were studied. RT-PCR analysis indicated that the term pregnancy myometria had little ERalpha mRNA, whereas the amounts of ERbeta mRNAs in pregnant or nonpregnant myometria appeared to be similar. Both ERalpha and ERbeta mRNA were greater in certain leiomyoma than in normal nonpregnant myometria. The binding kinetics revealed that two specific binding sites (with high or low affinity) for 17beta-estradiol were present in the nonpregnant myometrium. Only the low-affinity binding sites were detectable in late-pregnancy myometria and in leiomyoma, and their capacities were increased two- to threefold (P < 0.001) in leiomyoma. The pregnancy- and leiomyoma-related changes in myometrial ER status, especially the low concentration of ERalpha mRNA and the lack of high-affinity ER in pregnant women, plus the increased ERalpha and ERbeta mRNAs and the increased low-affinity ER in some leiomyoma, suggest that the redistribution of ER subtypes is associated with the pathological and/or normal growth of the myometrium.  (+info)

Leiomyoma is a benign (non-cancerous) tumor that originates from the smooth muscle cells. It most commonly occurs in the uterus, where it is also known as a fibroid, but can also develop in other parts of the body such as the skin, gastrointestinal tract, and genitourinary system. Leiomyomas are typically slow-growing and often cause no symptoms, although they can lead to various complications depending on their size and location. Treatment options for leiomyomas include surveillance, medication, or surgical removal.

Uterine neoplasms refer to abnormal growths in the uterus, which can be benign (non-cancerous) or malignant (cancerous). These growths can originate from different types of cells within the uterus, leading to various types of uterine neoplasms. The two main categories of uterine neoplasms are endometrial neoplasms and uterine sarcomas.

Endometrial neoplasms develop from the endometrium, which is the inner lining of the uterus. Most endometrial neoplasms are classified as endometrioid adenocarcinomas, arising from glandular cells in the endometrium. Other types include serous carcinoma, clear cell carcinoma, and mucinous carcinoma.

Uterine sarcomas, on the other hand, are less common and originate from the connective tissue (stroma) or muscle (myometrium) of the uterus. Uterine sarcomas can be further divided into several subtypes, such as leiomyosarcoma, endometrial stromal sarcoma, and undifferentiated uterine sarcoma.

Uterine neoplasms can cause various symptoms, including abnormal vaginal bleeding or discharge, pelvic pain, and difficulty urinating or having bowel movements. The diagnosis typically involves a combination of imaging tests (such as ultrasound, CT, or MRI scans) and tissue biopsies to determine the type and extent of the neoplasm. Treatment options depend on the type, stage, and patient's overall health but may include surgery, radiation therapy, chemotherapy, or hormone therapy.

The myometrium is the middle and thickest layer of the uterine wall, composed mainly of smooth muscle cells. It is responsible for the strong contractions during labor and can also contribute to bleeding during menstruation or childbirth. The myometrium is able to stretch and expand to accommodate a growing fetus and then contract during labor to help push the baby out. It also plays a role in maintaining the structure and shape of the uterus, and in protecting the internal organs within the pelvic cavity.

Epithelioid Leiomyoma is a rare type of benign (non-cancerous) smooth muscle tumor. It arises from the muscularis mucosa or the smooth muscle layer of blood vessels in the gastrointestinal tract, particularly in the esophagus and stomach.

Epithelioid Leiomyomas are composed of epithelioid cells, which have an appearance similar to epithelial cells, but they are actually smooth muscle cells with an altered shape and size. These tumors typically appear as well-circumscribed masses, and they usually do not invade surrounding tissues or metastasize (spread) to other organs.

The diagnosis of Epithelioid Leiomyoma is based on histopathological examination, which involves the examination of tissue samples under a microscope. Immunohistochemical staining may also be used to confirm the presence of smooth muscle markers and exclude other malignant tumors with similar morphology.

Treatment typically involves surgical excision of the tumor, and the prognosis is generally excellent, with a low risk of recurrence. However, close follow-up is recommended to monitor for any potential recurrences or changes in the tumor's behavior.

Leiomyomatosis is a medical term that refers to the benign growth (non-cancerous) of smooth muscle cells, which form tumors known as leiomyomas or fibroids. These growths can occur in various parts of the body, including the skin, uterus, gastrointestinal tract, and other organs.

The term "leiomyomatosis" is often used to describe a condition where multiple smooth muscle tumors develop in a single organ or throughout the body. For example:

1. Cutaneous leiomyomatosis - Multiple benign tumors of the smooth muscle in the skin.
2. Uterine leiomyomatosis - Multiple fibroids in the uterus, also known as uterine fibroids or myomas.
3. Gastrointestinal stromal tumor (GIST) leiomyomatosis - Multiple benign smooth muscle tumors in the gastrointestinal tract.
4. Disseminated peritoneal leiomyomatosis - Multiple benign smooth muscle tumors spread across the peritoneum, the lining of the abdominal cavity.

These conditions are usually not cancerous but can cause various symptoms depending on their location and size. Treatment options may include surveillance, medication, or surgical removal of the tumors.

An angiomyoma is a benign tumor that is composed of both blood vessels and smooth muscle cells. It is also known as a vascular leiomyoma. These types of tumors can occur in various parts of the body, but when they occur in the uterus, they are often referred to as fibroids. Angiomyomas are typically slow-growing and asymptomatic, but in some cases, they may cause symptoms such as heavy menstrual bleeding, pelvic pain, or pressure on surrounding organs. Treatment options for angiomyomas may include observation, medication, or surgical removal.

A uterine myomectomy is a surgical procedure that involves removing uterine fibroids, which are noncancerous growths that develop in the muscular wall of the uterus. The surgery aims to preserve the uterus, unlike a hysterectomy, where the entire uterus is removed.

During the myomectomy procedure, the surgeon makes an incision in the uterus, carefully extracts the fibroids, and then closes the incision. The approach to the surgery can vary depending on factors such as the size, number, and location of the fibroids:

1. Abdominal myomectomy: An open surgical procedure where an incision is made in the lower abdomen to access the uterus directly. This method is typically used when there are numerous or large fibroids.
2. Laparoscopic myomectomy: A minimally invasive procedure that involves making several small incisions in the abdomen, through which a laparoscope (a thin, lighted tube with a camera) and specialized surgical instruments are inserted to perform the surgery. This method is often preferred for smaller fibroids and when preserving the uterus is essential.
3. Hysteroscopic myomectomy: Another minimally invasive procedure that involves inserting a hysteroscope through the cervix into the uterine cavity to remove submucosal fibroids (fibroids that grow into the inner cavity of the uterus). No abdominal incisions are required for this approach.

Recovery time and postoperative discomfort will vary depending on the type of myomectomy performed, but generally, minimally invasive procedures result in quicker recoveries and fewer complications compared to open surgeries.

Leiomyosarcoma is a type of cancer that arises from the smooth muscle cells, which are responsible for the involuntary contractions of various organs and blood vessels. It most commonly occurs in the uterus, soft tissues (such as muscles and fat), and the gastrointestinal tract.

Leiomyosarcomas can vary in their aggressiveness and may spread to other parts of the body (metastasize) through the bloodstream or lymphatic system. The prognosis for leiomyosarcoma depends on several factors, including the location and size of the tumor, the patient's age and overall health, and the extent of metastasis. Treatment typically involves surgical removal of the tumor, along with radiation therapy and/or chemotherapy to help prevent recurrence or spread of the cancer.

A hysterectomy is a surgical procedure that involves the removal of the uterus (womb). Depending on the specific medical condition and necessity, a hysterectomy may also include the removal of the ovaries, fallopian tubes, and surrounding tissues. There are different types of hysterectomies, including:

1. Total hysterectomy: The uterus and cervix are removed.
2. Supracervical (or subtotal) hysterectomy: Only the upper part of the uterus is removed, leaving the cervix intact.
3. Radical hysterectomy: This procedure involves removing the uterus, cervix, surrounding tissues, and the upper part of the vagina. It is typically performed in cases of cervical cancer.
4. Oophorectomy: The removal of one or both ovaries can be performed along with a hysterectomy depending on the patient's medical condition and age.
5. Salpingectomy: The removal of one or both fallopian tubes can also be performed along with a hysterectomy if needed.

The reasons for performing a hysterectomy may include but are not limited to: uterine fibroids, heavy menstrual bleeding, endometriosis, adenomyosis, pelvic prolapse, cervical or uterine cancer, and chronic pelvic pain. The choice of the type of hysterectomy depends on the patient's medical condition, age, and personal preferences.

A smooth muscle tumor refers to a growth that develops in the smooth muscles, which are involuntary muscles found in various organs and structures throughout the body, including the digestive tract, uterus, blood vessels, and bladder. These tumors can be benign (noncancerous) or malignant (cancerous).

Benign smooth muscle tumors are called leiomyomas. They are typically slow-growing and rarely spread to other parts of the body. Leiomyomas are often asymptomatic but can cause problems depending on their location. For instance, a leiomyoma in the uterus might lead to heavy menstrual periods or difficulty becoming pregnant.

Malignant smooth muscle tumors are called leiomyosarcomas. These tumors are more aggressive and have a higher risk of spreading to other parts of the body. Symptoms can vary widely depending on the location of the tumor but may include abdominal pain, bloating, or bleeding.

It's important to note that while some smooth muscle tumors can be removed surgically, others may require additional treatment such as radiation therapy or chemotherapy, especially in cases of leiomyosarcomas. Regular follow-up with a healthcare provider is essential to monitor for recurrence and manage any potential complications.

Norpregnadienes are a type of steroid hormone that are structurally similar to progesterone, but with certain chemical groups (such as the methyl group at C10) removed. They are formed through the metabolism of certain steroid hormones and can be further metabolized into other compounds.

Norpregnadienes have been studied for their potential role in various physiological processes, including the regulation of reproductive function and the development of certain diseases such as cancer. However, more research is needed to fully understand their functions and clinical significance.

Uterine artery embolization (UAE) is a minimally invasive procedure used to treat certain conditions related to the uterus and uterine fibroids. The procedure involves blocking or reducing the blood flow to the fibroids, causing them to shrink and alleviating symptoms such as heavy menstrual bleeding, pain, and pressure.

During the procedure, an interventional radiologist makes a small incision in the groin area and inserts a catheter into the femoral artery. The catheter is then guided to the uterine arteries using fluoroscopic imaging. Once in place, tiny particles are injected through the catheter to block or reduce the blood flow to the fibroids. This process may be performed on one or both uterine arteries, depending on the location and size of the fibroids.

UAE is typically an outpatient procedure, and most women can return home the same day. Recovery time varies but is generally shorter than that of a hysterectomy, which is the surgical removal of the uterus. Potential risks associated with UAE include infection, bleeding, damage to nearby organs, and premature menopause in some cases. However, these complications are relatively rare.

Menorrhagia is a medical term used to describe abnormally heavy or prolonged menstrual periods. It's often characterized by the loss of an excessive amount of menstrual blood (usually more than 80 ml) and can last longer than normal, typically over seven days. This condition can have significant impacts on a woman's quality of life, causing fatigue, distress, and restrictions in daily activities due to the need for frequent pad or tampon changes.

The causes of menorrhagia are varied and can include hormonal imbalances, uterine fibroids or polyps, endometrial hyperplasia, pelvic inflammatory disease, pregnancy complications, certain medications, and underlying medical conditions such as coagulopathies or thyroid disorders. In some cases, the cause may remain undetermined even after a thorough evaluation.

Treatment options for menorrhagia depend on the underlying cause and range from medication management with hormonal therapies, nonsteroidal anti-inflammatory drugs (NSAIDs), or tranexamic acid to procedural interventions like endometrial ablation, hysteroscopic resection of polyps or fibroids, or ultimately hysterectomy in severe cases. It is essential for individuals experiencing menorrhagia to consult with their healthcare provider to determine the best course of action based on their specific situation and medical history.

Preserved food, in a medical context, refers to food that has been treated or processed in order to inhibit spoilage and prolong its shelf life. This is typically achieved through methods such as canning, pickling, smoking, drying, or freezing. These processes work by reducing the moisture content, increasing acidity, or introducing chemicals that prevent the growth of bacteria, fungi, and other microorganisms that can cause foodborne illness.

While preserved foods can be a valuable source of nutrition, especially in situations where fresh food is not available, it's important to note that some preservation methods can also introduce harmful substances, such as sodium nitrite in cured meats or acrylamide in fried or baked starchy foods. Therefore, preserved foods should be consumed in moderation as part of a balanced diet.

Transforming Growth Factor-beta 3 (TGF-β3) is a type of cytokine, specifically a growth factor that belongs to the TGF-β family. It plays crucial roles in regulating various cellular processes such as proliferation, differentiation, apoptosis, and extracellular matrix production.

TGF-β3 has been identified to have significant functions during embryonic development and tissue repair. In particular, it is known to be involved in the regulation of wound healing and scar formation. TGF-β3 can influence the behavior of various cell types, including fibroblasts, epithelial cells, and immune cells.

In some cases, TGF-β3 has been investigated for its potential therapeutic use in reducing fibrosis and promoting tissue regeneration. However, more research is needed to fully understand its mechanisms and potential clinical applications.

Selenium-binding proteins (Se-binding proteins) are a group of proteins that contain selenocysteine, an amino acid containing selenium. Selenocysteine is incorporated into these proteins at specific positions during protein synthesis, and it plays a crucial role in the function of Se-binding proteins.

One of the most well-known Se-binding proteins is glutathione peroxidase (GPx), an antioxidant enzyme that protects cells from oxidative damage by reducing hydrogen peroxide and lipid peroxides to water and alcohols, respectively. Other Se-binding proteins include thioredoxin reductase, which plays a role in redox regulation, and iodothyronine deiodinases, which are involved in thyroid hormone metabolism.

Se-binding proteins have been identified in various organisms, including bacteria, archaea, and eukaryotes. In humans, Se-binding proteins are found in a variety of tissues, including the liver, kidney, and brain. The expression and activity of Se-binding proteins can be influenced by factors such as selenium status, oxidative stress, and inflammation.

Intestinal neoplasms refer to abnormal growths in the tissues of the intestines, which can be benign or malignant. These growths are called neoplasms and they result from uncontrolled cell division. In the case of intestinal neoplasms, these growths occur in the small intestine, large intestine (colon), rectum, or appendix.

Benign intestinal neoplasms are not cancerous and often do not invade surrounding tissues or spread to other parts of the body. However, they can still cause problems if they grow large enough to obstruct the intestines or cause bleeding. Common types of benign intestinal neoplasms include polyps, leiomyomas, and lipomas.

Malignant intestinal neoplasms, on the other hand, are cancerous and can invade surrounding tissues and spread to other parts of the body. The most common type of malignant intestinal neoplasm is adenocarcinoma, which arises from the glandular cells lining the inside of the intestines. Other types of malignant intestinal neoplasms include lymphomas, sarcomas, and carcinoid tumors.

Symptoms of intestinal neoplasms can vary depending on their size, location, and type. Common symptoms include abdominal pain, bloating, changes in bowel habits, rectal bleeding, weight loss, and fatigue. If you experience any of these symptoms, it is important to seek medical attention promptly.

Smooth muscle, also known as involuntary muscle, is a type of muscle that is controlled by the autonomic nervous system and functions without conscious effort. These muscles are found in the walls of hollow organs such as the stomach, intestines, bladder, and blood vessels, as well as in the eyes, skin, and other areas of the body.

Smooth muscle fibers are shorter and narrower than skeletal muscle fibers and do not have striations or sarcomeres, which give skeletal muscle its striped appearance. Smooth muscle is controlled by the autonomic nervous system through the release of neurotransmitters such as acetylcholine and norepinephrine, which bind to receptors on the smooth muscle cells and cause them to contract or relax.

Smooth muscle plays an important role in many physiological processes, including digestion, circulation, respiration, and elimination. It can also contribute to various medical conditions, such as hypertension, gastrointestinal disorders, and genitourinary dysfunction, when it becomes overactive or underactive.

APC (Adenomatous Polyposis Coli) gene is a tumor suppressor gene that provides instructions for making a protein called adenomatous polyposis coli. This protein plays a crucial role in regulating the growth and division of cells in the colon and rectum. Specifically, it helps to maintain the stability of the cell's genetic material (DNA) by controlling the process of beta-catenin degradation.

When the APC gene is mutated or altered, it can lead to an accumulation of beta-catenin in the cell, which can result in uncontrolled cell growth and division. This can ultimately lead to the development of colon polyps, which are benign growths that can become cancerous over time if left untreated.

Mutations in the APC gene are associated with several inherited cancer syndromes, including familial adenomatous polyposis (FAP) and attenuated FAP (AFAP). These conditions are characterized by the development of numerous colon polyps at a young age, which can increase the risk of developing colorectal cancer.

A smooth muscle within the vascular system refers to the involuntary, innervated muscle that is found in the walls of blood vessels. These muscles are responsible for controlling the diameter of the blood vessels, which in turn regulates blood flow and blood pressure. They are called "smooth" muscles because their individual muscle cells do not have the striations, or cross-striped patterns, that are observed in skeletal and cardiac muscle cells. Smooth muscle in the vascular system is controlled by the autonomic nervous system and by hormones, and can contract or relax slowly over a period of time.

The plural form can be either the English leiomyomas or the classical leiomyomata. Uterine fibroids are leiomyomata of the ... Leiomyomas of the skin are generally (1) acquired, and (2) divided into several categories: Solitary cutaneous leiomyoma ... vascular leiomyomas) that are thought to arise from vascular smooth muscle Dartoic (or genital) leiomyomas originating in the ... A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in ...
Bronchial leiomyomas are only 0.1% to 2% of benign lung tumours. Bronchial leiomyomas comprise 33-45% of respiratory system ... The first bronchial leiomyoma was described by in 1909. Saoud M, Patil M, Dhillon SS, Pokharel S, Picone A, Hennon M, et al. ( ... A bronchial leiomyoma is a relatively rare form of lung tumours. These tumours can form in the lower respiratory tract tissue ... The determination of a leiomyoma is done by chest x-rays, blood sample and taking a tissue sample of the tumor. An associated ...
Scrotal leiomyoma is considered to be an extremely rare type of genital leiomyoma. Because leiomyomas in the scrotum are ... Genital leiomyomas (also known as dartoic leiomyomas) are leiomyomas that originate in the dartos muscles, or smooth muscles, ... Vulvar leiomyomas are one the most prominent types of genital leiomyomas. Lesions to the vulva may be up to 15 cm in length and ... Genital leiomyoma can be symptomatic or asymptomatic and is dependent on the type of leiomyoma. In most cases, pain in the ...
... is a rare condition characterized by the growth of uterine leiomyoma in the other regions ... Fu, Yili; Li, Hui; Tian, Bo; Hu, Bin (2012). "Pulmonary benign metastasizing leiomyoma: a case report and review of the ... Ki, Eun; Hwang, Seon; Lee, Keun; Park, Jong; Hur, Soo (2013). "Benign metastasizing leiomyoma of the lung". World Journal of ... Chen, Shi; Liu, Rui-Ming; Li, Tian (27 February 2017). "Pulmonary benign metastasizing leiomyoma: a case report and literature ...
627 Multiple cutaneous leiomyoma Leiomyoma Skin lesion James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases ... Solitary cutaneous leiomyoma typically presents as a deeply circumscribed, freely movable, rounded nodule ranging from 2 to 15 ...
Multiple cutaneous leiomyomas, also known as Pilar leiomyomas, arise from the arrectores pilorum muscles, and are made up of a ... Sometimes associated with uterine leiomyomas (a combination known as multiple cutaneous and uterine leiomyomatosis, MCUL), ...
Gastric leiomyoma". Am. J. Pathol. 97 (3): 504. PMC 2042425. PMID 389064. Prichard, R (December 1979). "Selected items from the ...
A syndrome (Reed's syndrome) that causes uterine leiomyomata along with cutaneous leiomyomata and renal cell cancer has been ... Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women with ... There is no consensus among pathologists regarding the transformation of leiomyoma into a sarcoma. There are a number of rare ... "Uterus - Stromal tumors - Leiomyoma". pathology Outlines. Topic Completed: 1 August 2011. Revised: 15 December 2019 Gupta JK, ...
Diagnosis may be aided by immunostaining; endometrial stromal nodules are positive for CD10; leiomyomas are positive for ...
However, refined mapping in leiomyomas and myeloid leukemias eventually pointed to CUX1 as the sole tumor suppressor gene in ... "Deletion 7q22 in uterine leiomyoma. A cytogenetic review". Cancer Genetics & Cytogenetics 1993, 71(1):1-6. Zeng WR, Scherer SW ... "Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma". Genes, Chromosomes & ... and KRAS in uterine leiomyomas". Molecular Carcinogenesis 2003, 37:61-4. Moon NS, Rong Zeng W, Premdas P, Santaguida M, Berube ...
... (vascular leiomyoma, angiomyoma) of the skin is thought to arise from vascular smooth muscle, and is generally ... Leiomyoma Skin lesions Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 1033. McGraw- ...
Shozu M, Murakami K, Inoue M (February 2004). "Aromatase and leiomyoma of the uterus". Seminars in Reproductive Medicine. 22 (1 ... "Aromatase in endometriosis and uterine leiomyomata". The Journal of Steroid Biochemistry and Molecular Biology. 95 (1-5): 57-62 ...
"Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1". Tete R, de Montgolfier R, Piante M (1971). "[Leiomyoma and ...
Pedeutour F, Ligon AH, Morton CC (November 1999). "[Genetics of uterine leiomyomata]". Bulletin du Cancer. 86 (11): 920-8. PMID ... uterine leiomyomas". Cancer Research. 59 (1): 19-23. PMID 9892177. Gattas GJ, Quade BJ, Nowak RA, Morton CC (August 1999). " ... "HMGIC expression in human adult and fetal tissues and in uterine leiomyomata". Genes, Chromosomes & Cancer. 25 (4): 316-22. doi ... and characterization of the chromosome 12 breakpoint cluster region of uterine leiomyomas". Genes, Chromosomes & Cancer. 11 (2 ...
Leiomyoma of deep soft tissue mimicking calcific myonecrosis. Radiol Case Rep. 2016;11(4):430‐433. Published 2016 Sep 17. doi: ...
Uterine artery embolization (UAE) is a common treatment with the etiology of a leiomyoma. The rate of serious complications is ... Hysteroscopic myomectomy is a minimally invasive surgical procedure to remove leiomyomas (otherwise known as fibroids). Though ... leiomyoma) - fibroids in the wall of the uterus cause increased menstrual loss if they protrude into the central cavity and ... "Uterine artery embolization for leiomyomata". Obstetrics & Gynecology. 98 (1): 29-34. doi:10.1016/S0029-7844(01)01382-5. ISSN ...
It is characterised by multiple cutaneous leiomyomas and, in women, uterine leiomyomas. It predisposes for renal cell cancer, ... Reed, W. B.; Walker, R.; Horowitz, R. (1973). "Cutaneous leiomyomata with uterine leiomyomata". Acta Dermato-Venereologica. 53 ... Leiomyomas do not typically require treatment unless they cause pain. The skin lesions may be difficult to treat as they tend ... These tumours may also arise in the tunica dartos of the scrotum and the mammillary muscle of the nipple (genital leiomyoma), ...
Intravenous leiomyomata are usually but not always associated with uterine fibroids, and tend to recur. This condition is ... IV Leiomyomas Video (Articles with short description, Short description is different from Wikidata, Benign neoplasms). ... Intravenous leiomyomatosis is a rare condition seen exclusively in women in which leiomyomata, benign smooth muscle tumors, are ... "Benign metastasizing leiomyoma: clonality, telomere length and clinicopathologic analysis". Modern Pathology. 19 (1): 130-140. ...
"Characterization of the uterine leiomyoma microRNAome by deep sequencing". Genomics. 99 (5): 275-81. doi:10.1016/j.ygeno. ...
Leiomyomas are seen in pre-menopausal women and are symptomatic 20-50% of the time, while leiomyosarcomas, the most common ... Since leiomyomas are benign and mostly asymptomatic, minimally invasive treatment modalities are used to treat them. For this ... Leiomyomas are benign smooth muscle tumors that have overlapping features with leiomyosarcomas. Although both originate from ... For example, the FDA has warned against using morcellation for benign leiomyomas as those with unsuspected sarcomas are at risk ...
Paracrine activation of WNT/beta-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.Proc Natl Acad Sci USA. ... "Role of stem cells in human uterine leiomyoma growth". PLOS ONE. 7 (5): e36935. Bibcode:2012PLoSO...736935O. doi:10.1371/ ...
WNT4 Multiple cutaneous and uterine leiomyomata; 150800; FH Multiple endocrine neoplasia IIA; 171400; RET Multiple endocrine ...
627 Leiomyoma Skin lesion List of cutaneous conditions James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases ...
They may have leiomyoma/schwannoma-like areas with nuclear palisading. They typically stain with CD34 and vimentin, and, ...
Stewart EA, Gostout B, Rabinovici J, Kim HS, Regan L, Tempany CM (2007). "Sustained relief of leiomyoma symptoms by using ...
Expression of TGIF is increased in uterine leiomyoma compared with myometrium. Yen-Ping Ho J, Man WC, Wen Y, Polan ML, Shih-Chu ... Ho E, Chen B (June 2009). "Transforming growth interacting factor expression in leiomyoma compared with myometrium". Fertil. ...
Bell's criteria do not apply to extrauterine tumors No or mild atypia, no tumor cell necrosis ⇒ leiomyoma. If 5 or more mitotic ... Hyalinizing necrosis is more common in leiomyomas. It consists of a zone of hyalinized collagen between dead cells and ... Necrosis secondary to ulceration in submucous leiomyomas features acute inflammatory cells and a peripheral reparative process ... leiomyosarcoma and uterine leiomyoma. none minimal: smooth nuclei, smooth contours, minimal variation in nuclear size, shape, ...
Walker also developed a groundbreaking animal model for uterine leiomyoma/fibroids. Walker and her husband Michael have two ...
Baek WK, Kim D, Jung N, Yi YW, Kim JM, Cha SD, Bae I, Cho CH (2003). "Increased expression of cyclin G1 in leiomyoma compared ...
Iwahashi M, Muragaki Y, Ino K (2012). "Human prolyl hydroxylase expression in uterine leiomyoma during the menstrual cycle". ...
The plural form can be either the English leiomyomas or the classical leiomyomata. Uterine fibroids are leiomyomata of the ... Leiomyomas of the skin are generally (1) acquired, and (2) divided into several categories: Solitary cutaneous leiomyoma ... vascular leiomyomas) that are thought to arise from vascular smooth muscle Dartoic (or genital) leiomyomas originating in the ... A leiomyoma, also known as a fibroid, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in ...
It is called an intestinal leiomyoma when the tumor is located in the intestinal tract. Most often, these tumors cause no ... It is called an intestinal leiomyoma when the tumor is located in the intestinal tract. Most often, these tumors cause no ... A leiomyoma is a benign tumor made up mostly of smooth muscle cells. ... A leiomyoma is a benign tumor made up mostly of smooth muscle cells. ...
The hereditary form, which causes, multiple leiomyomas, was originally noted by Kloepfer et al in 1958. ... Leiomyomas are benign soft tissue neoplasms that arise from smooth muscle; they were first described by Virchow in 1854. ... had only skin leiomyomas, and 7% had only uterine leiomyomas. [16] Uterine leiomyomas not associated with skin leiomyomas were ... Leiomyomas are uncommon. Piloleiomyomas are the most common, while genital leiomyomas tend to be the least common of the three ...
Although minimally invasive techniques are widely used for the surgical management of uterine leiomyoma, there is significant ... The full article, titled "Age-Stratified Risk of Unexpected Uterine Sarcoma Following Surgery for Presumed Benign Leiomyoma," ... New Model Predicts Risk of Unexpected Uterine Sarcoma Following Surgery for Presumed Benign Leiomyoma ... to identify a cohort of 2,075 women who had undergone myomectomy for presumed benign leiomyoma between 2005 and 2014. Within ...
A leiomyoma is a relatively harmless and non-spreading tumor that arises from the smooth muscle of the stomach and intestinal ... Leiomyoma of the Stomach, Small, and Large Intestine in Dogs. A leiomyoma is a relatively harmless and non-spreading tumor that ... Gastric leiomyoma is most common at the esophageal-gastric junction, where the esophagus meets the stomach cavity. If necessary ... In many cases, owing to their benign nature, even large leiomyomas with narrow margins can be removed successfully. ...
Rates of uterine leiomyomata (UL) are 2-3 times higher in African Americans than in European Americans. It is unclear whether ... African ancestry and genetic risk for uterine leiomyomata Am J Epidemiol. 2012 Dec 15;176(12):1159-68. doi: 10.1093/aje/kws276 ... Rates of uterine leiomyomata (UL) are 2-3 times higher in African Americans than in European Americans. It is unclear whether ...
Expert diagnosis and treatment of esophageal leiomyoma is available at St. Elizabeth Healthcare. ... Causes of Leiomyoma. A leiomyoma is generally a benign tumor that arises from the smooth muscle of esophagus. It is rare that ... A leiomyoma is a benign, smooth muscle tumor. It may also be called a fibroid. Leiomyoma is very rare, accounting for less than ... Symptoms of Leiomyoma. Leiomyomas rarely cause symptoms when they are smaller than 5 cm. in diameter. When they grow larger, ...
Endoscopic Resection of a Large Mediastinal Esophageal Leiomyoma. Kelly R Haisley, MD, Kevin Reavs, MD, Michael Antiporda, MD, ... Introduction: In this video, we review a case of the complex endoscopic removal of a large esophageal leiomyoma by a submucosal ... found to have a 2.5 by 4 centimeter mass in the mid esophagus consistent with a benign esophageal leiomyoma. Knowing that the ... the decision was made to proceed to the operating room for endoscopic resection of the leiomyoma. ...
Leiomyoma of the Urinary Bladder Floor: Diagnosis by Transvaginal Ultrasound Subject Area: Further Areas ... Transurethral Enucleation of Bladder Leiomyoma: A Series of Six Cases and Review of the Literature Urol Int (September,2018) ... Ferná;ndez Fernández, Mayayo Dehesa; Leiomyoma of the Urinary Bladder Floor: Diagnosis by Transvaginal Ultrasound. Urol Int 1 ... We studied a case of leiomyoma of the bladder floor in a woman with excretion urography, voiding cystourethrography, abdominal ...
RESULTS: Women with higher LH were more likely to have leiomyomata (adjusted odds ratios for second and third tertiles were 1.7 ... Age, an independent risk factor for leiomyomata, was not affected by inclusion of LH in the logistic models. CONCLUSIONS: As ... Luteinizing hormone in premenopausal women may stimulate uterine leiomyomata development. Baird, DD., Kesner, JS., & Dunson, DB ... METHODS: Randomly selected women, aged 35 to 49 years, from a prepaid health plan were screened for leiomyomata with pelvic ...
Mojgan Mohammadi Uterine leiomyomas are the most common solid tumors in the female reproductive tract, occurring in 20% to 40% ... Leiomyomas: Uterine Fibroid Embolization. Mahmood K. Razavi, Mojgan Mohammadi. Uterine leiomyomas are the most common solid ... Transcervical expulsion of leiomyomas may occur in 1% to 2% of patients and is associated with pain and bleeding. These are ... Delayed passage of leiomyomas for up to a year after UFE has also been reported.24 ...
She developed a large, pedunculated uterine leiomyoma at age 28 years. To our knowledge, uterine leiomyoma in association with ... Leiomyoma of uterus in a patient with ring chromosome 12: case presentation and literature review Am J Med Genet. 1996 May 17; ...
Cutaneous Leiomyoma, Thigh. Description:. Photograph of many small, red bumps on an individuals thigh.. Fotografía de muchos ... Cutaneous leiomyomas are benign (not cancer) tumors that form in the muscle tissue around a hair follicle. Here they are shown ...
Fibroids (Uterine Leiomyoma). Definition. Uterine fibroids are tumors or lumps made of muscle cells and other tissue that grow ... Uterine Leiomyoma (pronounced YOU-ter-in lee-oh-my-OH-mah). Causes. Currently, we know little about what causes uterine ...
Typical appearances of leiomyomas are easily recognised on imaging. This article is available only as a PDF. Please click on ... Uterine leiomyomas are the most common gynaecological tumour. ... Uterine leiomyomas are the most common gynaecological tumour. ... Typical appearances of leiomyomas are easily recognised on imaging.. This article is available only as a PDF. Please click on " ... Introduction: We report an unusual case of a large cystic, pedunculated uterine leiomyoma mimicking a primary malignant ovarian ...
December 2012 CASE REPORT Vaginal leiomyoma in pregnancy presenting as a prolapsed vaginal mass Cem Dane, Yaprak Rustemoglu, ... Vaginal leiomyomas are rare benign solid tumours of the vagina. They can cause mechanical dystocia, which is a common problem ... Vaginal leiomyoma in pregnancy presenting as a prolapsed vaginal mass. Cem Dane, Yaprak Rustemoglu, Murat Kiray, Unsal ... Here we describe a patient with a vaginal leiomyoma diagnosed during the mid-trimester that could have caused dystocia. This 22 ...
In this puma, it was diagnosed the presence of leiomyoma in the uterus wall. There was not found any report of uterus leiomyoma ... Leiomyoma is a benign tumor with smooth muscle origin, low frequency in domestic animals, and like the others neoplasias, ... Although suggestive of leiomyoma in the histopathologic exam, it was decided to do an immunohistochemistry to find the origin ... The objective of this paper was to describe the occurrence of leiomyoma in a captive puma (Puma concolor) in Brazil. ...
Previously, these tumors were classified as GI leiomyomas, leiomyosarcomas, leiomyoblastomas, or schwannomas, on the basis of ... Gastrointestinal Stromal Tumors (Leiomyoma/Leiomyosarcoma) Imaging * Sections Gastrointestinal Stromal Tumors (Leiomyoma/ ... 4] Only with tumors in the esophagus does the term leiomyoma remain accurate. Leiomyomas are the most common mesenchymal tumors ... Gastrointestinal Stromal Tumors (Leiomyoma/Leiomyosarcoma) Imaging Updated: Sep 02, 2020 * Author: Vu H Nguyen, MD; Chief ...
... and findings of histologic examination supported a diagnosis of esophageal leiomyoma. TREATMENT AND OUTCOME In view of numerous ... Chronic regurgitation or vomiting caused by oesophageal leiomyoma in three dogs. J Am Anim Hosp Assoc 1994;30:425-430. ... Chronic regurgitation or vomiting caused by oesophageal leiomyoma in three dogs. J Am Anim Hosp Assoc 1994;30:425-430. ... Chronic regurgitation or vomiting caused by oesophageal leiomyoma in three dogs. J Am Anim Hosp Assoc 1994;30:425-430. ...
Atypical pilar leiomyoma. Cutaneous counterpart of uterine symplastic leiomyoma? Am J Dermatopathol2001;23:299-303. ... the different variants include classic leiomyoma,1,2 leiomyoblastoma,3 and vascular leiomyoma,4 this last tumour being the most ... as recently suggested by Mahalingam and Goldberg in atypical pilar leiomyoma.13 Finally, atypical leiomyoma with myxoid change ... Bizarre leiomyomas of the uterus: a comprehensive pathologic study of 24 cases with long-term follow-up. Am J Surg Pathol1997; ...
Unusual case of a leiomyoma in the space of Retzius mimicking broad ligament fibroid ... Unusual case of a leiomyoma in the space of Retzius mimicking broad ligament fibroid ...
Abstract: Uterine leiomyoma, frequently known as fibroid, is a benign smooth muscle tumor that occurs in women between the ages ... The prevalence f uterine leiomyoma is clinically apparent in up to 25% of women, with nearly 80 ... read more% of black women ... Uterine leiomyoma is also the greatest contributor to infertility in the US. Currently, the mainstream method of treatment is ... Uterine leiomyoma is a collection of hyperplastic uterine smooth muscle, along with endothelial cells, fibroblast, collagen, ...
Green tea uterine fibroids research shows that EGCG kills leiomyoma tumor cells of the uterus, reducing the incidence and size ... Several studies show that EGCG in the diet increased cell death (apoptosis) of leiomyoma (fibroid tumors), reduced the number ... Green tea extract inhibits proliferation of unterine leiomyoma cells in vitro and in nude mice, American Journal Obstet Gynecol ... and soy isoflavones also reduced leiomyomas in quail during previous research. These studies are considered preliminary and ...
PET/CT of Delayed Uterine Leiomyoma Metastasizing to Lung and Femur Kenneth N. Huynh and Ba D. Nguyen ...
Speculum exam revealed a mass protruding through the cervical canal highly suggestive of a prolapsed leiomyoma. After surgical ... We hypothesize that a preexisting submucosal leiomyoma became colonized by neoplastic plasma cells with resultant expansion and ... protrusion of the leiomyoma through the cervical canal. This case highlights a rare presentation of an extraosseous ... within the female genital tract and to our knowledge is the first reported case of a plasmacytoma involving a leiomyoma. ...
Fibroids (uterine myomatosis, leiomyomas). Vollenhoven, B. J. & Lethaby, A., 2015, In: Clinical Evidence. 06, p. 814-829 16 p. ... Fibroids (uterine myomatosis, leiomyomas). Lethaby, A. & Vollenhoven, B., Jun 2003, In: Clinical Evidence. 9, p. 2028-2043 16 p ... Fibroids (uterine myomatosis, leiomyomas). Lethaby, A. & Vollenhoven, B., 2011, In: Clinical Evidence. 2011, p. 2028-2043 16 p. ... Fibroids (uterine myomatosis, leiomyomas). Lethaby, A. & Vollenhoven, B., Dec 2005, In: Clinical Evidence. 14, p. 2264-2282 19 ...
Prostate Leiomyoma: Read more about Symptoms, Diagnosis, Treatment, Complications, Causes and Prognosis. ... keywords: Leiomyoma Prostatic leiomyoma Benign prostatic tumors Article These are the options to access the [elsevier.es] ... Leiomyoma is a benign tumor and has excellent prognosis when complete resection is applied and atypia is not detected.4 On our ... References 1. Hossain D., Meiers I., Qian J. Prostatic leiomyoma with atypia: follow-up study of 10 cases. [ncbi.nlm.nih.gov] ...
Uterine leiomyoma was first discovered by Hippocrates in 460-375 B.C and called it "uterine stone". Uterine leiomyoma may be ... Differentiating Leiomyoma from other Diseases. Differentiating Leiomyoma from Other Diseases Disease entity Etiology (Genetic ... Pelvic ultrasound is helpful in the diagnosis of uterine leiomyoma.. *Findings on an ultrasound diagnostic of uterine leiomyoma ... The majority of patients with leiomyoma are usually asymptomatic.. *Symptoms of uterine leiomyoma may include the following:[ ...
Pedunculated leiomyomas of the uterus are not uncommon. However, parasitic leiomyomas of the uterus have been described only ... If pedunculated subserosal leiomyoma develops an extremely long tenuous stalk, it is called a wandering or migrating leiomyoma ... They are then called parasitic leiomyomas [1,2]. Rarely, a parasitic leiomyoma may become torsive and cause an acute abdomen [3 ... Impression was ?exophytic uterine leiomyoma. Histopathology of excised mass was suggestive of leiomyoma.. References. *Robbins ...
Leiomyoma of the Lower Eyelid. Vivian Lee, MD; Amir A. Azari, MD; Sarah Nehls, MD; et al Heather A. Potter, MD; Daniel M. ... Leiomyoma of the Lower Eyelid. JAMA Ophthalmol. 2013;131(8):1085. doi:10.1001/jamaophthalmol.2013.1492 ...
  • Although minimally invasive techniques are widely used for the surgical management of uterine leiomyoma, there is significant controversy regarding the use of morcellation to remove bulky tumors laparoscopically. (prweb.com)
  • Leiomyoma is very rare, accounting for less than 1% of esophageal tumors. (stelizabeth.com)
  • Uterine leiomyomas are the most common solid tumors in the female reproductive tract, occurring in 20% to 40% of women in the reproductive age. (sls.org)
  • Cutaneous leiomyomas are benign (not cancer) tumors that form in the muscle tissue around a hair follicle. (cancer.gov)
  • Previously, these tumors were classified as GI leiomyomas, leiomyosarcomas, leiomyoblastomas, or schwannomas, on the basis of histologic findings and the fact that these tumors apparently originate in the muscularis propria layer of the intestinal wall. (medscape.com)
  • Further analyses seek to define the Wnt signaling mechanisms and are focused on our lab's unique organotypic model of leiomyoma, in which human fibroid tumors are grown in immune-compromised mice. (tufts.edu)
  • Several studies show that EGCG in the diet increased cell death (apoptosis) of leiomyoma (fibroid tumors), reduced the number of tumors, and reduced the size of tumors. (green-tea-health-news.com)
  • Another green tea uterine fibroids study showed significant decreases in proliferation cell nuclear antigen (PCNA) and cyclin-dependent kinase 4 (Cdk4) for tumors reduced in volume and weight (Zhang D et al, Green tea extract inhibits proliferation of unterine leiomyoma cells in vitro and in nude mice, American Journal Obstet Gynecol, March 2010). (green-tea-health-news.com)
  • It is thought that leiomyoma is the result of either transformation of normal uterine muscle cells into abnormal cells through somatic mutations , or through the growth of abnormal uterine muscle cells into tumors. (wikidoc.org)
  • Leiomyomas are the most common benign uterine tumors. (casereports.in)
  • Leiomyomas are the commonest benign tumors of the uterus. (casereports.in)
  • Leiomyomas are benign tumors of myometrium. (jpgo.org)
  • Leiomyomas of the urterus (or uterine fibroids) are benign tumors that arise from the overgrowth of smooth muscle and connective tissue in the uterus. (medscape.com)
  • Leiomyoma, the commonest benign tumor of the uterus is a rare occurrence in the oral cavity and when present mimics various other soft tissue tumors of the oral cavity and lead to a diagnostic dilemma to the clinician. (bvsalud.org)
  • Leiomyomas are benign smooth muscle tumors that are relatively common, especially in the uterus (about 95%) followed by the gastrointestinal tract and skin 2 . (bvsalud.org)
  • Mason s trichrome and Van Geison s stains are specific for muscle cells and collagen fibers whereas Mallory s Phosphotungstic Acid (PTAH) and positive IHC marker desmin may aid to differentiate leiomyoma from other spindle cell tumors such as myofibroblastoma 4 . (bvsalud.org)
  • Leiomyomas or uterine fibroids are benign tumors of the uterus that consist of smooth muscle and extracellular matrix collagen and elastin. (mims.com)
  • Cervical leiomyomas are benign smooth-muscle tumors. (msdmanuals.com)
  • Uterine Fibroids Uterine fibroids (leiomyomas) are benign smooth muscle tumors of the uterus. (msdmanuals.com)
  • Vaginal leiomyomas are rare solid tumors which occur in middle aged females aged across 35 to 50 years of age. (medimagingcasereports.com)
  • Although leiomyoma is the most common benign esophageal tumor, malignant carcinoma is still 50 times more likely. (wikipedia.org)
  • A leiomyoma is a benign tumor made up mostly of smooth muscle cells. (medlineplus.gov)
  • It is called an intestinal leiomyoma when the tumor is located in the intestinal tract. (medlineplus.gov)
  • A leiomyoma is a relatively harmless and non-spreading tumor that arises from the smooth muscle of the stomach and intestinal tract. (petmd.com)
  • A leiomyoma is a benign, smooth muscle tumor. (stelizabeth.com)
  • A leiomyoma is generally a benign tumor that arises from the smooth muscle of esophagus. (stelizabeth.com)
  • Leiomyoma is a benign tumor with smooth muscle origin, low frequency in domestic animals, and like the others neoplasias, rarely described in wild felids. (vin.com)
  • The results of the alpha smooth muscle and the muscular actin antibodies characterized the tumor as a leiomyoma. (vin.com)
  • Gastric gastrointestinal stromal tumor (GIST) en face. (medscape.com)
  • Abstract: Uterine leiomyoma, frequently known as fibroid, is a benign smooth muscle tumor that occurs in women between the ages of 30-55 years old. (tufts.edu)
  • Palabras clave: Leiomioma Leiomioma de próstata Tumor benigno de próstata Abstract We present a case of pure prostatic leiomyoma, benign and rare entity, diagnosed in a patient with prostatism. (symptoma.com)
  • Leiomyoma is a benign tumor and has excellent prognosis when complete resection is applied and atypia is not detected.4 On our case, no atypia was reported related with the prostatic leiomyoma. (symptoma.com)
  • Review of the pathophysiology , diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor. (symptoma.com)
  • Leiomyoma is the most common tumor of the uterus and female pelvis. (jpgo.org)
  • Histopathological examination of the tumor removed confirmed the diagnosis of a leiomyoma. (jpgo.org)
  • DISCUSSION Leiomyoma is a tumor of smooth muscle cells. (scarscenter.com)
  • Leiomyoma is the most common pelvic tumor of the uterus. (jpgo.org)
  • Fine needle aspiration (FNA) of the tumor showed a spindle cell tumor consistent with a leiomyoma. (figshare.com)
  • Metastatic leiomyoma are an extremely rare complication after surgery to remove the uterus for uterine fibroids. (wikipedia.org)
  • In this puma, it was diagnosed the presence of leiomyoma in the uterus wall. (vin.com)
  • There was not found any report of uterus leiomyoma in big cats in captivity in Brazil, only the report of a leiomyosarcoma in mammary gland with metastasis in multiple organs in a captive jaguar ( Panthera onca ). (vin.com)
  • Diagnosis of pedunculated leiomyoma can be established by ultrasound which shows palpable mass separate from uterus and ovaries. (casereports.in)
  • Pedunculated leiomyomas of the uterus are not uncommon. (casereports.in)
  • If a pelvic mass is palpable separate from the uterus and ovaries then ultrasound diagnoses of pedunculated leiomyoma can be established. (casereports.in)
  • However, parasitic leiomyomas of the uterus have been described only rarely in the ultrasonographic literature [ 3 - 5 ]. (casereports.in)
  • A computed tomography of the abdomen and pelvis showed the presence of multiple leiomyomas in the uterine fundus and body of the uterus, ranging in size from 8.3 to 11 cm (figure 1). (jpgo.org)
  • The leiomyoma was found to be passing to the right side of the uterus behind the cervix, and inferiorly. (jpgo.org)
  • CT scan of abdomen-pelvis -suggestive of multiple leiomyomas in the fundus and body of uterus. (jpgo.org)
  • Intraoperative findings: uterus yellow arrow, left fallopian tube (green arrow), and left ovary (white arrow) stretched over the large left broad ligament leiomyoma. (jpgo.org)
  • D25.2 is a valid billable ICD-10 diagnosis code for Subserosal leiomyoma of uterus . (icd10coded.com)
  • Angioleiomyoma is a relatively rare type of leiomyoma of the uterus that originates from smooth muscle cells and contains thickwalled vessels. (ejgo.net)
  • Associated with papillary variant of renal cell carcinoma and multiple cutaneous leiomyoma. (wikipedia.org)
  • The importance of correct diagnosis of cutaneous leiomyoma lies in the association of multiple cutaneous leiomyomas with uterine fibroids and papillary renal cell carcinoma in what is known as Reed syndrome, or hereditary leiomyomatosis and renal cell cancer (HLRCC), an autosomal dominant disorder. (medscape.com)
  • In the retrospective analysis, the research team examined the Mount Sinai Data Warehouse (MSDW) database, which includes data on more than 3 million patients, to identify a cohort of 2,075 women who had undergone myomectomy for presumed benign leiomyoma between 2005 and 2014. (prweb.com)
  • We additionally present a review of the literature on development of parasitic leiomyoma after myomectomy, summarizing 35 published cases in addition to our own. (sls.org)
  • Parasitic leiomyomas, Myomectomy, Uncontained morcellation. (sls.org)
  • Most symptomatic cervical leiomyomas are removed by myomectomy (particularly if childbearing capacity is important) or, if myomectomy is technically difficult, by hysterectomy. (msdmanuals.com)
  • Surgically remove symptomatic cervical leiomyomas, usually by myomectomy but, if myomectomy is not possible, by hysterectomy. (msdmanuals.com)
  • A subsequent U.S. Food and Drug Administration review found a higher prevalence of unsuspected uterine sarcoma and LMS among patients undergoing myomectomy or hysterectomy for presumed benign leiomyomas than was previously reported. (qxmd.com)
  • A pedunculated, subserosal uterine leiomyoma with extensive cystic degeneration can mimic an ovarian tumour on imaging and should be considered in the differential diagnosis of an adnexal mass. (annals.edu.sg)
  • Immunohistochemical evidence for leiomyogenic markers coupled with the low mitotic rate, the lack of an infiltrating growth pattern, and the indolent clinical course led to the diagnosis of atypical leiomyoma with prominent myxoid change. (bmj.com)
  • The patient underwent hysterectomy with a diagnosis of recurrent cotyledonoid dissecting leiomyoma. (istinye.edu.tr)
  • The aim of the present study is to report an unusual case of oral leiomyoma mimicking a gingival epulis and demonstrate the importance of the immunohistochemical results in determining the final diagnosis. (bvsalud.org)
  • These histomorphologic features and the IHC profile lead to the diagnosis of an oral leiomyoma. (bvsalud.org)
  • Diagnosis of cervical leiomyomas is by physical examination. (msdmanuals.com)
  • Uterine fibroids are leiomyomata of the uterine smooth muscle. (wikipedia.org)
  • Uterine leiomyomas (also called fibroids) may be assessed by Doppler ultrasonography assessment before uterine artery embolization. (medscape.com)
  • Cervical leiomyomas do not prolapse, but some submucosal fibroids prolapse through the cervical canal into the vagina. (msdmanuals.com)
  • Laparoscopic hysterectomy and excision of vaginal fibroid was performed to remove the vaginal fibroids and subsequent histopathology examination confirmed a vaginal leiomyoma. (medimagingcasereports.com)
  • Gastric leiomyoma is most common at the esophageal-gastric junction, where the esophagus meets the stomach cavity. (petmd.com)
  • In this video, we review a case of the complex endoscopic removal of a large esophageal leiomyoma by a submucosal resection technique extending into the mediastinum. (sages.org)
  • The patient is a healthy 38 year old woman with dysphagia, found to have a 2.5 by 4 centimeter mass in the mid esophagus consistent with a benign esophageal leiomyoma. (sages.org)
  • Lateral radiographic images of the thorax and cranial portion of the abdomen of a 10-year-old spayed female Rottweiler with a 2-month history of regurgitation and weight loss, despite no apparent changes in appetite, that was subsequently deemed to have esophageal leiomyoma. (avma.org)
  • A 27-year-old woman underwent a video-assisted thoracoscopic enucleation of a giant horseshoe esophageal leiomyoma. (figshare.com)
  • Ultrasonography showed a right broad ligament leiomyoma measuring 3.8x3.5 cm and a right ovarian simple cyst measuring 3.5x1.5 cm. (jpgo.org)
  • She followed up for surgery after 6 months, and a repeat scan done now showed an 8.5x9.1 cm sized right broad ligament leiomyoma with significant increase in size as compared to previous scan and a right ovarian simple cyst of 2.7x1.7 cm. (jpgo.org)
  • We report a case of a 30 year old woman with a 26 weeks' size broad ligament leiomyoma. (jpgo.org)
  • Cutaneous leiomyomas can develop wherever smooth muscles are present, but malignant transformation probably does not occur. (medscape.com)
  • If your leiomyoma is small and not expected to be malignant, you may be advised to take a wait and watch approach that includes regular barium swallows and endoscopy to help monitor your condition. (stelizabeth.com)
  • We report an unusual case of a large cystic, pedunculated uterine leiomyoma mimicking a primary malignant ovarian tumour on sonography and computed tomography (CT). (annals.edu.sg)
  • Rarely, uterine leiomyomas may undergo malignant degeneration to become a sarcoma. (medscape.com)
  • The true incidence of malignant transformation is difficult to determine, because leiomyomas are common, whereas malignant leiomyosarcomas are rare and can arise de novo. (medscape.com)
  • In this report, we discuss the aggressive clinical course of a patient with recurrent cotyledonoid dissecting leiomyoma resulting in hysterectomy, which has been reported in a limited number of studies in the literature. (istinye.edu.tr)
  • Surgical management of presumed benign uterine leiomyomas received popular media attention when a case of disseminated LMS occurred after laparoscopic power morcellator-assisted hysterectomy. (qxmd.com)
  • The broad ligament is the commonest extrauterine site for the occurance of a leiomyoma. (jpgo.org)
  • The broad ligament is the commonest extrauterine site for the occurrence of leiomyoma. (jpgo.org)
  • 1] Extrauterine leiomyomas may develop in the broad ligament or at other sites where smooth muscle exists. (jpgo.org)
  • Surgical excision or ablation of leiomyomas may be helpful for some symptomatic women. (medscape.com)
  • In addition, the risk-prediction model may play a role in shaping future surgical guidelines used in the management of leiomyoma. (prweb.com)
  • Surgical resection: removal or enucleation of the leiomyoma. (stelizabeth.com)
  • Transvaginal surgical enucleation of the vaginal leiomyoma is usually curative and recommended as the initial treatment of choice to prevent for dystocia. (hkmj.org)
  • 3] Broad ligament leiomyomas pose diagnostic and surgical difficulties. (jpgo.org)
  • Parasitic leiomyoma is estimated to occur after 0.20 to 1.25% of laparoscopic myomectomies, and is diverse in it's presenting symptoms and surgical findings. (sls.org)
  • 2 So far, the different variants include classic leiomyoma, 1, 2 leiomyoblastoma, 3 and vascular leiomyoma, 4 this last tumour being the most common histotype. (bmj.com)
  • The World Health Organization (WHO) distinguishes three types of leiomyomas: leiomyoma (solid), angiomyoma (vascular leiomyoma) and epitheloid leiomyoma (leioblastoma) 9 . (bvsalud.org)
  • Rarely, a parasitic leiomyoma may become torsive and cause an acute abdomen [ 3 ]. (casereports.in)
  • Parasitic leiomyoma is a rare condition that may be spontaneous or iatrogenic in origin. (sls.org)
  • Laparoscopic uterine surgery and tissue morcellation are procedures that may lead to the development of parasitic leiomyoma. (sls.org)
  • Treatment with relugolix combination for up to 52 weeks yields sustained reductions in heavy menstrual bleeding as well as subsequent increases in iron stores in women with uterine leiomyomas , as shown in a study. (mims.com)
  • OBJECTIVE: To evaluate the effects of transdermal hormone replacement therapy (HRT) on uterine and leiomyoma size and on uterine bleeding patterns in postmenopausal women with uterine leiomyomas. (uniroma1.it)
  • Seventy postmenopausal women with uterine leiomyomas were enrolled and treated for 12 cycles of 28 days each with transdermal 17 beta-estradiol (E(2)) patches plus oral medroxyprogesterone acetate continuously added (group A) or with calcium carbonate (group B). At entry and every three cycles, uterine and leiomyoma dimensions were measured by transvaginal ultrasonography. (uniroma1.it)
  • We hypothesize that a preexisting submucosal leiomyoma became colonized by neoplastic plasma cells with resultant expansion and protrusion of the leiomyoma through the cervical canal. (dtic.mil)
  • On speculum examination, sometimes a prolapsed submucosal leiomyoma is visible at or beyond the external cervical os. (msdmanuals.com)
  • A prolapsed submucosal leiomyoma may be friable and ulcerated. (msdmanuals.com)
  • Although suggestive of leiomyoma in the histopathologic exam, it was decided to do an immunohistochemistry to find the origin of the neoplastic cells. (vin.com)
  • Speculum exam revealed a mass protruding through the cervical canal highly suggestive of a prolapsed leiomyoma. (dtic.mil)
  • Histopathological examination revealed tumour composed of interlacing bundles of smooth muscles with oedematous intervening stroma suggestive of leiomyoma (Figure 1d). (ommegaonline.org)
  • Abdominopelvic ultrasonography showed a large heterogenous lesion of 20x18 cm in the uterine fundus, suggestive of a leiomyoma. (jpgo.org)
  • The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
  • Pathology showed atypical spindle cell neoplasm, favoring pleomorphic leiomyoma. (scarscenter.com)
  • The low incidence of this lesion, the unusual location, and its histomorphological pattern of presentation which needs to be differentiated from other spindle cell lesions posing a diagnostic challenge makes the report of this case worthy in a 32-year-old male, with a soft tissue swelling of the right lower gingiva which appeared to be an epulis but finally turned out to be a leiomyoma. (bvsalud.org)
  • Mesenchymal neoplasms of the gallbladder are rare and in particular leiomyomas of the gallbladder have been rarely reported, all of them in patients with immune system disorders. (wikipedia.org)
  • Cutaneous leiomyomas are benign soft-tissue neoplasms that arise from smooth muscle (arrector pili). (medscape.com)
  • In many cases, owing to their benign nature, even large leiomyomas with narrow margins can be removed successfully. (petmd.com)
  • large leiomyomas may partially block the urinary tract. (msdmanuals.com)
  • The measurement of hemoglobin and/or hematocrit levels might be considered in patients with multiple leiomyomas, because erythrocytosis is reported in rare cases. (medscape.com)
  • Two thousand one hundred twelve patients with symptomatic leiomyomata were eligible for long-term follow-up at 27 sites representing a geographically diverse set of practices, including academic centers, community hospitals, and closed-panel health maintenance organizations. (duke.edu)
  • Only one case of atypical leiomyoma has been described previously at this location, 5 although it did not display myxoid change. (bmj.com)
  • Myxoid degeneration of leiomyoma is one of the rarer types of degeneration that can occur in a uterine leiomyoma . (pacs.de)
  • This term is related but not identical to the term myxoid uterine leiomyoma . (pacs.de)
  • Subserosal leiomyomas may be beneath the uterine surface, exophytic or pedunculated. (casereports.in)
  • If pedunculated subserosal leiomyoma develops an extremely long tenuous stalk, it is called a wandering or migrating leiomyoma [ 1 ]. (casereports.in)
  • In 1809, the first laparotomy was conducted by Ephraim McDowell to treat leiomyoma in Danville, USA. (wikidoc.org)
  • During laparotomy, a large mesosalpingeal leiomyoma measuring 10x12 cm was found on the left side, with left utero-ovarian ligament stretched posteriorly and left fallopian tube stretched anteriorly over it (figure 1). (jpgo.org)
  • The purpose of this article is to provide background on the epidemiologic, clinical, and economic impact of uterine leiomyomas, summarize the concerns associated with treating women with potential occult leiomyosarcomas (LMSs), and review the known and emerging imaging features of typical and atypical leiomyomas and explain how to differentiate them from LMSs. (qxmd.com)
  • However, genital leiomyomas are usually asymptomatic solitary lesions arising from the dartoic, vulvar, or mammillary muscles in the genital region or on the nipple. (medscape.com)
  • This case highlights a rare presentation of an extraosseous plasmacytoma within the female genital tract and to our knowledge is the first reported case of a plasmacytoma involving a leiomyoma. (dtic.mil)
  • However, of a uterine leiomyoma with other genital blood tests on the woman were normal and organs unaffected. (who.int)
  • As other leiomyomata, they are benign, but may lead to excessive menstrual bleeding (menorrhagia), often cause anemia and may lead to infertility. (wikipedia.org)
  • Laboratory testing is generally not necessary for evaluation of leiomyomas unless there is abnormal vaginal bleeding or to rule out other conditions. (medscape.com)
  • Vaginal leiomyomas are rare benign solid tumours of the vagina. (hkmj.org)
  • Here we describe a patient with a vaginal leiomyoma diagnosed during the mid-trimester that could have caused dystocia. (hkmj.org)
  • Vaginal leiomyoma most commonly arises from the anterior vaginal wall. (medimagingcasereports.com)
  • Ultrasonography and magnetic resonance images (MRI) revealed multiple vaginal leiomyomas. (medimagingcasereports.com)
  • Rare Case of Vaginal Leiomyoma - A Case Report. (medimagingcasereports.com)
  • Leiomyomas are rare solid tumours of the ovary accounting for 0.5 - 1% of the benign ovarian tumours [1] . (ommegaonline.org)
  • Primary leiomyoma of the ovary (PLO) is rare with less than 100 cases reported in English literature [5,6] . (ommegaonline.org)
  • Stage of surgery almost near the point of removal of the leiomyoma: LO - left ovary, LUOL - left utero-ovarian ligament, L - leiomyoma, LFT - left fallopian tube. (jpgo.org)
  • Stage of surgery after removal of the leiomyoma: MS - mesosalpinx, LB - leiomyoma bed, LFT - left fallopian tube, LO - left ovary. (jpgo.org)
  • There is a marked decrease of CCN5 in uterine leiomyoma as compared to the normal myometrium from the same patient. (tufts.edu)
  • Our preliminary results using qRT-PCR in an analysis of patient matched uterine leiomyoma and myometrium show a decrease in both the HBP1 and CCN5 mRNAs. (tufts.edu)
  • Pelvic ultrasound revealed uterine enlargement, multiple small leiomyomas, and a large mass in the myometrium. (ejgo.net)
  • Durham, NC (PRWEB) March 12, 2015 -- In a study published in The Oncologist on March 12, 2015, researchers describe the development of a new model that predicts the risk of unexpected uterine sarcoma in women undergoing minimally invasive procedures for the removal of presumed benign leiomyoma. (prweb.com)
  • To help quantify this risk, a team of researchers led by Andrew S. Brohl, MD, at the Icahn School of Medicine at Mount Sinai in New York, NY, retrospectively evaluated the incidence of unexpected uterine sarcoma among women undergoing minimally invasive leiomyoma removal at Mount Sinai facilities since 2005. (prweb.com)
  • We are presenting a case of giant ovarian leiomyoma in a young lady which was suspected as germ cell tumour on imaging. (ommegaonline.org)
  • Patient was kept under observation for the left ovarian leiomyoma. (ommegaonline.org)
  • An incision was made parallel and above the left utero-ovarian ligament and the leiomyoma was enucleated avoiding injury to the fallopian tube. (jpgo.org)
  • True broad ligament leiomyomas arise from the muscle fibers normally found in the mesometrium, like the round ligament, utero-ovarian ligament and connective tissue surrounding the ovarian and the uterine vessels. (jpgo.org)
  • We studied a case of leiomyoma of the bladder floor in a woman with excretion urography, voiding cystourethrography, abdominal echography, computed tomography scan, and transvaginal echography. (karger.com)
  • Diagnose cervical leiomyomas by pelvic examination and sometimes transvaginal ultrasonography or MRI. (msdmanuals.com)
  • Transvaginal uterine artery ligation in a woman with uterine leiomyomas. (bvsalud.org)
  • Histology was that of a leiomyoma with extensive cystic degeneration. (annals.edu.sg)
  • On histopathological examination, a leiomyoma with cystic and hyaline degeneration was seen. (jpgo.org)
  • Microscopically, the benign leio- multiple calcified bilharzial ova myoma showed multiple epitheloid granu- lomas with calcified bilharzial ova within the leiomyoma. (who.int)
  • Figure 3 Two calcified bilharzial ova within the leiomyoma which, as in our case, be seen long after the original infection. (who.int)
  • Leiomyomas rarely cause symptoms when they are smaller than 5 cm. in diameter. (stelizabeth.com)
  • OBJECTIVE: Human chorionic gonadotropin (hCG) has proliferative effects on uterine smooth muscle and leiomyoma tissue in vitro. (rti.org)
  • Uterine leiomyoma is a collection of hyperplastic uterine smooth muscle, along with endothelial cells, fibroblast, collagen, and sulfate proteoglycan. (tufts.edu)
  • The symptoms for a 30-year-old male with a 10 cm leiomyoma included "dead leg" pains. (wikipedia.org)
  • Prostatic leiomyomas can present with voiding difficulties or obstructive symptoms 1. (symptoma.com)
  • Most cervical leiomyomas eventually cause symptoms. (msdmanuals.com)
  • The resultant granulomatous inflammation had possibly influenced the Figure 1 An epithelioid granuloma within the size of the fibroid, explaining its relatively leiomyoma large size in this patient. (who.int)