Lens Diseases
Lenses
Contact Lenses, Hydrophilic
Lens Cortex, Crystalline
Lens Capsule, Crystalline
Cataract
Crystallins
Lens Subluxation
Lens epithelial changes and mutated gene expression in patients with myotonic dystrophy. (1/72)
AIMS: Examination of the expression of the mutated allele of myotonic dystrophy protein kinase gene and lens epithelial cell changes in patients with myotonic dystrophy. METHODS: Six eyes from three patients with myotonic dystrophy underwent cataract surgery. The lens epithelium was photographed to examine the morphological changes. mRNAs were extracted to determine myotonic dystrophy protein kinase gene expression in the lens epithelium and peripheral blood. Age matched lens epithelial cells from senile cataracts were used as controls. RESULTS: All eyes showed iridescent or posterior subcapsular lens opacity. The expression of the myotonic dystrophy protein kinase gene with trinucleotide repeat expansion was evaluated by reverse transcriptase polymerase chain reaction, Southern blotting, and sequence analysis. Lens epithelial cell densities were extremely reduced in the patients compared with the control group. CONCLUSION: To the authors' knowledge, this is the first report to describe the relation between lens epithelial cell changes and mutated gene expression in patients with myotonic dystrophy. The gene may be mitotically unstable in the lens epithelial cells; it may influence cell density and lens epithelial function, and it may lead to the development of typical subcapsular lens opacity. (+info)Equine phacoclastic uveitis: the clinical manifestations, light microscopic findings, and therapy of 7 cases. (2/72)
This retrospective clinical study describes the clinical manifestations, light microscopic findings, and diagnosis and treatment of acute and chronic lens rupture in the horse. Rupture of the lens capsule in the horse usually results in a chronic, blinding inflammation (phacoclastic uveitis) unless prompt surgical and medical therapies are implemented. The clinical manifestations of acute lens capsule rupture included: cataract; intralenticular displacement of iridal pigment; lens cortical fragments attached to the perforated lens capsule, iris, and corneal endothelium; miosis; aqueous flare; and usually a corneal or scleral perforation with ulceration or focal full thickness corneal edema and scarring. The clinical signs of chronic phacoclastic uveitis include blindness, phthisis bulbi, and generalized corneal opacification related to scarring, vascularization, pigmentation, and edema. In one horse, acute phacoclastic uveitis was successfully treated with phacoemulsification to remove the ruptured lens and medical therapy to control the accompanying inflammation. The affected eyes of the horses with chronic phacoclastic uveitis were enucleated because of persistent clinical signs of nonulcerative keratitis and uveitis, despite long-term medical management. The clinical manifestations and lack of improvement with medical therapy are similar in the horse, dog, cat, and rabbit. However, the histologic findings in equine phacoclastic uveitis differ significantly from those in the dog, and rabbit. (+info)Herpes simplex virus DNA in the lens one year after an episode of retinitis. (3/72)
The present report describes a case where HSV was detected by polymerase chain reaction (PCR) in the lens cortical material removed during cataract surgery one year after resolution of retinal inflammation in a patient with ARN. (+info)Intraoperative complications during cataract surgery in the very old. (4/72)
PURPOSE: To determine if there is a difference in intraoperative complications during cataract surgery in very old patients (> or = 88 years) compared with younger patients (< 88 years). METHODS: The records of 802 consecutive cataract operations were reviewed. Identical techniques of small-incision phacoemulsification were used in all cases. A total of 102 eyes were in patients aged 88 to 98, designated as the "very old." The remaining 700 eyes were in patients under 88, designated as "younger." The incidence of intraoperative complications in the 2 groups was compared. RESULTS: Posterior capsule tears, vitreous loss, and loss of the nucleus were found as complications. Overall, these events occurred in 10% of the very old and in only 3% of those under age 88. Vitreous loss occurred in 7% of the very old and in only 1.6% of those under 88. There was 1 dropped nucleus in the very old. In the younger patients, 90.5% of eyes with complicated surgery achieved 20/40 visual acuity or better, but only 40% of complicated cases in the very old achieved this. Furthermore, 50% of complicated cases in the very old had visual acuity of 20/200 or worse, all directly attributed to surgical difficulties. Fifteen percent of patients in both groups had trabeculectomies with no influence on complications. We noted that 8% of the very old required pupil stretching compared with 2% of those under 88. CONCLUSIONS: This study strongly suggests that very old patients (i.e., those 88 years and older) have a higher incidence of intraoperative complications during cataract surgery than younger patients. Furthermore, such complications may result in severe visual loss. These findings may have significance as the population ages. (+info)Causes of severe visual impairment and blindness in children attending schools for the visually handicapped in the Czech Republic. (5/72)
AIMS: To describe the causes of severe visual impairment and blindness in children in schools for the visually handicapped in the Czech Republic in 1998. METHODS: Pupils attending all 10 primary schools for the visually handicapped were examined. A modified WHO/PBL eye examination record for children with blindness and low vision was used. RESULTS: 229 children (146 males and 83 females) aged 6-15 years were included in the study: 47 children had severe visual impairment (20.5%) (visual acuity in their better eye less than 6/60), and 159 were blind (69.5%) (visual acuity in their better eye less than 3/60). Anatomically, the most affected parts of the eye were the retina (124, 54.2%), optic nerve (35, 15.3%), whole globe (25, 10.9%), lens (20, 8.7%), and uvea (12, 5.2%). Aetiologically (timing of insult leading to visual loss), the major cause of visual impairment was retinopathy of prematurity (ROP) (96, 41.9 %), followed by abnormalities of unknown timing of insult (97, 42.4%), and hereditary disease (21, 9.2%). In 90 children (40%), additional disabilities were present: mental disability (36, 16%), physical handicap (16, 7%), and/or a combination of both (19, 8%). It was estimated that 127 children (56%) suffer from visual impairment caused by potentially preventable and/or treatable conditions (for example, ROP, cataract, glaucoma). CONCLUSIONS: Establishing a study group for comprehensive evaluation of causes of visual handicap in children in the Czech Republic, as well as for detailed analysis of present practice of screening for ROP was recommended. (+info)Fibrous congenital iris membranes with pupillary distortion. (6/72)
BACKGROUND: In 1986 Cibis and associates described 2 children with a new type of congenital pupillary-iris-lens membrane with goniodysgenesis that was unilateral, sporadic, and progressive. These membranes were different from the common congenital pupillary strands that extend from 1 portion of the iris collarette to another or from the iris collarette to a focal opacity on the anterior lens surface. They also differed from the stationary congenital hypertrophic pupillary membranes that partially occlude the pupil, originating from multiple sites on the iris collarette, but not attaching directly to the lens. CASE MATERIAL: The present report is an account of 7 additional infants with congenital iris membranes, similar to those reported by Cibis and associates, which caused pupillary distortion and were variably associated with adhesions to the lens, goniodysgenesis, and progressive occlusion or seclusion of the pupil. Six of the 7 patients required surgery to open their pupils for visual purposes or to abort angle closure glaucoma. A remarkable finding was that the lenses in the area of the newly created pupils were clear, allowing an unobstructed view of normal fundi. CONCLUSION: This type of fibrous congenital iris membrane is important to recognize because of its impact on vision and its tendency to progress toward pupillary occlusion. Timely surgical intervention can abort this progressive course and allow vision to be preserved. (+info)Exogenous Pseudomonas endophthalmitis: a cause of lens enucleation. (7/72)
Pseudomonas aeruginosa eye infection, although uncommon, may be a devastating disease if not recognised and treated appropriately, especially in premature infants. The case is presented of a premature baby who lost her right eye from invasive exogenous Ps aeruginosa eye infection. (+info)Multiple developmental defects derived from impaired recruitment of ASC-2 to nuclear receptors in mice: implication for posterior lenticonus with cataract. (8/72)
ASC-2, a recently isolated transcriptional coactivator molecule, stimulates transactivation by multiple transcription factors, including nuclear receptors. We generated a potent dominant negative fragment of ASC-2, encompassing the N-terminal LXXLL motif that binds a broad range of nuclear receptors. This fragment, termed DN1, specifically inhibited endogenous ASC-2 from binding these receptors in vivo, whereas DN1/m, in which the LXXLL motif was mutated to LXXAA to abolish the receptor interactions, was inert. Interestingly, DN1 transgenic mice but not DN1/m transgenic mice exhibited severe microphthalmia and posterior lenticonus with cataract as well as a variety of pathophysiological phenotypes in many other organs. Our results provide a novel insight into the molecular and histopathological mechanism of posterior lenticonus with cataract and attest to the importance of ASC-2 as a pivotal transcriptional coactivator of nuclear receptors in vivo. (+info)Lens diseases refer to conditions that affect the lens of the eye, which is a transparent structure located behind the iris and pupil. The main function of the lens is to focus light onto the retina, enabling clear vision. Here are some examples of lens diseases:
1. Cataract: A cataract is a clouding of the lens that affects vision. It is a common age-related condition, but can also be caused by injury, disease, or medication.
2. Presbyopia: This is not strictly a "disease," but rather an age-related change in the lens that causes difficulty focusing on close objects. It typically becomes noticeable in people over the age of 40.
3. Lens dislocation: This occurs when the lens slips out of its normal position, usually due to trauma or a genetic disorder. It can cause vision problems and may require surgical intervention.
4. Lens opacity: This refers to any clouding or opacification of the lens that is not severe enough to be considered a cataract. It can cause visual symptoms such as glare or blurred vision.
5. Anterior subcapsular cataract: This is a type of cataract that forms in the front part of the lens, often as a result of injury or inflammation. It can cause significant visual impairment.
6. Posterior subcapsular cataract: This is another type of cataract that forms at the back of the lens, often as a result of diabetes or certain medications. It can also cause significant visual impairment.
Overall, lens diseases can have a significant impact on vision and quality of life, and may require medical intervention to manage or treat.
In the context of medical terminology, "lenses" generally refers to optical lenses used in various medical devices and instruments. These lenses are typically made of glass or plastic and are designed to refract (bend) light in specific ways to help magnify, focus, or redirect images. Here are some examples:
1. In ophthalmology and optometry, lenses are used in eyeglasses, contact lenses, and ophthalmic instruments to correct vision problems like myopia (nearsightedness), hypermetropia (farsightedness), astigmatism, or presbyopia.
2. In surgical microscopes, lenses are used to provide a magnified and clear view of the operating field during microsurgical procedures like ophthalmic, neurosurgical, or ENT (Ear, Nose, Throat) surgeries.
3. In endoscopes and laparoscopes, lenses are used to transmit light and images from inside the body during minimally invasive surgical procedures.
4. In ophthalmic diagnostic instruments like slit lamps, lenses are used to examine various structures of the eye in detail.
In summary, "lenses" in medical terminology refer to optical components that help manipulate light to aid in diagnosis, treatment, or visual correction.
Contact lenses are thin, curved plastic or silicone hydrogel devices that are placed on the eye to correct vision, replace a missing or damaged cornea, or for cosmetic purposes. They rest on the surface of the eye, called the cornea, and conform to its shape. Contact lenses are designed to float on a thin layer of tears and move with each blink.
There are two main types of contact lenses: soft and rigid gas permeable (RGP). Soft contact lenses are made of flexible hydrophilic (water-absorbing) materials that allow oxygen to pass through the lens to the cornea. RGP lenses are made of harder, more oxygen-permeable materials.
Contact lenses can be used to correct various vision problems, including nearsightedness, farsightedness, astigmatism, and presbyopia. They come in different shapes, sizes, and powers to suit individual needs and preferences. Proper care, handling, and regular check-ups with an eye care professional are essential for maintaining good eye health and preventing complications associated with contact lens wear.
Hydrophilic contact lenses are a type of contact lens that is designed to absorb and retain water. These lenses are made from materials that have an affinity for water, which helps them to remain moist and comfortable on the eye. The water content of hydrophilic contact lenses can vary, but typically ranges from 30-80% by weight.
Hydrophilic contact lenses are often used to correct refractive errors such as myopia (nearsightedness), hyperopia (farsightedness), and astigmatism. They can be made in a variety of materials, including soft hydrogel and silicone hydrogel.
One advantage of hydrophilic contact lenses is that they tend to be more comfortable to wear than other types of contacts, as they retain moisture and conform closely to the shape of the eye. However, they may also be more prone to deposits and buildup, which can lead to protein accumulation and discomfort over time. Proper care and cleaning are essential to maintain the health of the eyes when wearing hydrophilic contact lenses.
Intraocular lenses (IOLs) are artificial lens implants that are placed inside the eye during ophthalmic surgery, such as cataract removal. These lenses are designed to replace the natural lens of the eye that has become clouded or damaged, thereby restoring vision impairment caused by cataracts or other conditions.
There are several types of intraocular lenses available, including monofocal, multifocal, toric, and accommodative lenses. Monofocal IOLs provide clear vision at a single fixed distance, while multifocal IOLs offer clear vision at multiple distances. Toric IOLs are designed to correct astigmatism, and accommodative IOLs can change shape and position within the eye to allow for a range of vision.
The selection of the appropriate type of intraocular lens depends on various factors, including the patient's individual visual needs, lifestyle, and ocular health. The implantation procedure is typically performed on an outpatient basis and involves minimal discomfort or recovery time. Overall, intraocular lenses have become a safe and effective treatment option for patients with vision impairment due to cataracts or other eye conditions.
The crystalline lens in the eye is composed of three main parts: the capsule, the cortex, and the nucleus. The lens cortex is the outer layer of the lens, located between the capsule and the nucleus. It is made up of proteins and water, and its primary function is to help refract (bend) light rays as they pass through the eye, contributing to the focusing power of the eye.
The cortex is more flexible than the central nucleus, allowing it to change shape and adjust the focus of the eye for different distances. However, with age, the lens cortex can become less elastic, leading to presbyopia, a common age-related condition that affects the ability to focus on close objects. Additionally, changes in the lens cortex have been associated with cataracts, a clouding of the lens that can impair vision.
The crystalline lens of the eye is covered by a transparent, elastic capsule known as the lens capsule. This capsule is made up of collagen and forms the continuous outer layer of the lens. It is highly resistant to both physical and chemical insults, which allows it to protect the lens fibers within. The lens capsule is important for maintaining the shape and transparency of the lens, which are essential for proper focusing of light onto the retina.
The lens nucleus, also known as the crystalline lens nucleus, is the central part of the crystalline lens in the eye. The crystalline lens is a biconvex structure located behind the iris and pupil, which helps to refract (bend) light rays and focus them onto the retina.
The lens nucleus is composed of densely packed lens fibers that have lost their nuclei and cytoplasm during differentiation. It is surrounded by the lens cortex, which consists of younger lens fiber cells that are still metabolically active. The lens nucleus is relatively avascular and receives its nutrients through diffusion from the aqueous humor in the anterior chamber of the eye.
The lens nucleus plays an important role in the accommodation process, which allows the eye to focus on objects at different distances. During accommodation, the ciliary muscles contract and release tension on the lens zonules, allowing the lens to become thicker and increase its curvature. This results in a decrease in the focal length of the lens and enables the eye to focus on nearby objects. The lens nucleus is more rigid than the cortex and helps maintain the shape of the lens during accommodation.
Changes in the lens nucleus are associated with several age-related eye conditions, including cataracts and presbyopia. Cataracts occur when the lens becomes cloudy or opaque, leading to a decrease in vision clarity. Presbyopia is a condition that affects the ability to focus on near objects and is caused by a hardening of the lens nucleus and a loss of elasticity in the lens fibers.
A cataract is a clouding of the natural lens in the eye that affects vision. This clouding can cause vision to become blurry, faded, or dim, making it difficult to see clearly. Cataracts are a common age-related condition, but they can also be caused by injury, disease, or medication use. In most cases, cataracts develop gradually over time and can be treated with surgery to remove the cloudy lens and replace it with an artificial one.
Crystallins are the major proteins found in the lens of the eye in vertebrates. They make up about 90% of the protein content in the lens and are responsible for maintaining the transparency and refractive properties of the lens, which are essential for clear vision. There are two main types of crystallins, alpha (α) and beta/gamma (β/γ), which are further divided into several subtypes. These proteins are highly stable and have a long half-life, which allows them to remain in the lens for an extended period of time. Mutations in crystallin genes have been associated with various eye disorders, including cataracts and certain types of glaucoma.
Extended-wear contact lenses are a type of contact lens that is designed to be worn continuously, including during sleep, for an extended period of time. These lenses are typically made from materials that allow more oxygen to reach the eye, reducing the risk of eye irritation and infection compared to traditional overnight wear of non-extended wear lenses.
Extended-wear contact lenses can be worn for up to 30 days or longer, depending on the specific lens material and the individual's tolerance. However, it is important to note that even extended-wear contacts come with some risks, including a higher risk of eye infections and corneal ulcers compared to daily wear lenses. Therefore, it is essential to follow the recommended wearing schedule and replacement schedule provided by an eye care professional, as well as to have regular eye exams to monitor the health of the eyes.
Lens subluxation, also known as lens dislocation or ectopia lentis, is a condition where the lens of the eye becomes partially or completely displaced from its normal position. The lens is held in place by tiny fibers called zonules, which can become weakened or broken due to various reasons such as genetic disorders (like Marfan syndrome, homocystinuria, and Weill-Marchesani syndrome), trauma, inflammation, or cataract surgery complications. This displacement can lead to symptoms like blurry vision, double vision, sensitivity to light, or the appearance of a shadow in the peripheral vision. In some cases, lens subluxation may not cause any noticeable symptoms and can be discovered during routine eye examinations. Treatment options depend on the severity and underlying cause of the subluxation and may include eyeglasses, contact lenses, or surgical intervention to remove and replace the displaced lens with an intraocular lens (IOL).
Contact lens solutions are a type of disinfecting and cleaning solution specifically designed for use with contact lenses. They typically contain a combination of chemicals, such as preservatives, disinfectants, and surfactants, that work together to clean, disinfect, and store contact lenses safely and effectively.
There are several types of contact lens solutions available, including:
1. Multipurpose solution: This type of solution is the most commonly used and can be used for cleaning, rinsing, disinfecting, and storing soft contact lenses. It contains a combination of ingredients that perform all these functions in one step.
2. Hydrogen peroxide solution: This type of solution contains hydrogen peroxide as the main active ingredient, which is a powerful disinfectant. However, it requires a special case called a neutralizer to convert the hydrogen peroxide into water and oxygen before using the lenses.
3. Saline solution: This type of solution is used only for rinsing and storing contact lenses and does not contain any disinfecting or cleaning agents. It is often used in combination with other solutions for a complete contact lens care routine.
4. Daily cleaner: This type of solution is used to remove protein buildup and other deposits from the surface of contact lenses. It should be used in conjunction with a multipurpose or hydrogen peroxide solution as part of a daily cleaning routine.
It's important to follow the manufacturer's instructions carefully when using contact lens solutions to ensure that they are used safely and effectively. Failure to do so could result in eye irritation, infection, or other complications.
Sonia Anand
List of lentil diseases
CFAP298
List of dog diseases
Artificial enzyme
Adriana Briscoe
Chronic disease in Northern Ontario
Sociology of health and illness
Secondary glaucoma
Occult macular dystrophy
Glassblower's cataract
Progressive retinal atrophy
Fear of medical procedures
David Guwatudde
GAPO syndrome
Keratoconus
Pinhole occluder
Pumi dog
Volpino Italiano
Australian College of Optometry
Vence L. Bonham Jr.
Gas bubble disease
Soemmering ring
Marshall B. Ketchum University
Health professional
Human eye
Johnson & Johnson Vision
Phacomorphic glaucoma
Medical prescription
Naturalistic disease theories
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Centers for Diseas2
- Centers for Disease Control and Prevention. (cdc.gov)
- The US Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) have alerted healthcare professionals to increasing reports of Fusarium fungal eye infections in contact lens wearers. (yourlawyer.com)
Cataract9
- The weakness and dialysis of lens zonule after cataract surgery may lead to dislocation of intraocular lens (IOL). (nih.gov)
- The smoothening does not complicate the fabrication complexity of the lens and yet yields the same optical performance in treating presbyopia and assisting people after cataract surgery, but with about one order of magnitude smaller. (sciencedaily.com)
- He has been published several times and lectures nationally on various topics including OSD, dry eye, cataract surgery, pharmacology, corneal diseases and LASIK. (aaopt.org)
- 2) cataract diagnosis as a normal lens, cataract or a postoperative eye and (3) detection of referable cataracts with respect to aetiology and severity. (bmj.com)
- Cataract is an eye disease in which the otherwise clear lens becomes cloudy. (anton-paar.com)
- Excerpted from BCSC 2020-2021 series: Section 11 - Lens and Cataract . (aao.org)
- According to CDC in 2022, approximately 17.2 percent of the U.S. citizens above 40 years of age reported to have been detected of cataract at least in one eye which is approximately 20.5 million people of which only 6.1 million Americans had performed cataract surgery and replaced with new lenses, thus depicting huge market potential for cataract surgeries. (visiongain.com)
- A cataract is a "clouding" of the eye's natural lens which can interfere with a person's quality of vision and make normal activities such as driving a car at night or reading a newspaper increasingly difficult. (cascadebusnews.com)
- In the early stages of a cataract, stronger lighting and eye glasses may lessen vision problems caused by the clouding of the lens. (cascadebusnews.com)
Cataracts4
- Cataracts, which are cloudy areas in the lens of the eye. (nih.gov)
- A molecular characteristic of cataracts is the pathological clumping of the highly concentrated, solute proteins of the lens of the eye. (anton-paar.com)
- Therefore, the composition and opacity of the eye lenses of young and aging mice with and without a predisposition to cataracts were examined. (anton-paar.com)
- Using small-angle X-ray scattering (SAXS) and other methods, the researchers observed that the balance of the three most common proteins in the lens that developed cataracts - alpha, beta and gamma crystalline - was particularly disturbed. (anton-paar.com)
Alzheimer's Disease7
- This is more than twice the number of people living with cancer and more than the number of people living with HIV and Alzheimer's disease combined. (nih.gov)
- I currently work on developing and characterizing Quasi-Elastic Light (QLS) scattering and confocal fluorescent correlation spectroscopy (cFCS) instruments with the purpose of developing early non-invasive diagnostics for Alzheimer's Disease and radiation exposure. (bu.edu)
- Alzheimer's disease amyloid-ß pathology in the lens of the eye. (bu.edu)
- Alzheimer's disease (AD) is the most common form of dementia affecting the growing aging population today, with prevalence expected to rise over the next 35 years. (frontiersin.org)
- The growth in life expectancy and the developing aging population has led to the increased prevalence of chronic diseases, such as Alzheimer's disease (AD). (frontiersin.org)
- Alzheimer's disease is a heterogeneous disease and has multiple cognitive subtypes. (frontiersin.org)
- The variant of AD in which visual symptoms are prominent due to the localized pathology in the parieto-occipital region is often referred to as visual variant Alzheimer's disease (VVAD) ( 13 ). (frontiersin.org)
Rigid gas permeable2
- A rigid gas permeable lens sits entirely on the cornea, but because there is tear film between the contact lens and the cornea, there is improved vision and optics. (cybersight.org)
- Preferences vary, but most surgeons require the eyes to be several weeks free from rigid gas permeable (RGP) lenses, and less time for soft contact lenses. (aao.org)
Retina4
- Damaged blood vessels can harm the retina, causing a disease called diabetic retinopathy. (nih.gov)
- If the disease gets worse, some blood vessels close off, which causes new blood vessels to grow, or proliferate, on the surface of the retina. (nih.gov)
- Some people are born with this problem, or it might develop from a degenerative disease involving the retina, and that usually can't be treated. (webmd.com)
- Rosenthal's lenses can't cure all blind people, only those whose blindness is caused by certain diseases of the cornea, the clear lens that focuses light onto the retina. (harvard.edu)
Hydrogel5
- Researchers at the University of New Hampshire have created a hydrogel that could one day be made into a contact lens to more effectively treat corneal melting. (nih.gov)
- The factors included use of extended-wear hydrogel lenses, male gender, smoking, and the late winter months. (medscape.com)
- Hydrogel lenses are an older material. (cybersight.org)
- And the more popular polymer today is the silicone hydrogel lens. (cybersight.org)
- The device consists of a translu-cent latanoprost-polymer film, cut into a ring shape and encapsulated inside a contact lens lathed from methafilcon, a poly-HEMA based hydrogel. (aao.org)
Crystalline1
- Crystalline lens. (nih.gov)
Primary Care Optometry2
- Additionally, Dr. Spear completed a Residency in Primary Care Optometry/Ocular Disease at Northeastern State University College of Optometry, in Tahlequah Oklahoma and earned a Master's in Business Administration from Auburn University. (aaopt.org)
- NECO offers residencies in cornea and contact lens, ocular disease, pediatric optometry, primary care optometry, and vision rehabilitation. (neco.edu)
Glaucoma6
- Glaucoma is a group of eye diseases that can damage the optic nerve-the bundle of nerves that connects the eye to the brain. (nih.gov)
- Swiss biotech firm Sensimed was an early adopter of smart lens technology, to monitor the progression of glaucoma. (cnn.com)
- When it came to eye and other diseases linked to the eyes, nearly 67 percent said that they believed glaucoma was preventable with proper eye care when, in fact, it can only be treated not prevented. (foxnews.com)
- A latanoprost-eluting contact lens is showing early promise of being a controlled-release drug delivery system that could help ophthalmologists over-come the problem of their glaucoma patients' nonadherence to eye drop reg-imens. (aao.org)
- In a rare preclinical study published by Oph-thalmology , 1 researchers reported that cynomolgus monkeys with experi-mentally induced glaucoma who wore the contact lenses for 7 days at a time showed sustained reductions in intra-ocular pressure (IOP) throughout the test periods. (aao.org)
- Although glaucoma is the disease we studied here, this is in fact a plat-form technology," Dr. Kohane said. (aao.org)
Keratitis13
- 1 ) detailed the 2004-2007 outbreak of Acanthamoeba keratitis (AK) in persons wearing soft contact lenses who used Complete MoisturePlus (CMP) multipurpose contact lens solution (Advanced Medical Optics, Santa Ana, CA, USA). (cdc.gov)
- Verani JR , Lorick SA , Yoder JS , Beach MJ , Braden CR , Roberts JM , National outbreak of Acanthamoeba keratitis associated with use of a contact lens solution, United States. (cdc.gov)
- Levy B , Heiler D , Norton S . Report on testing from an investigation of Fusarium keratitis in contact lens wearers. (cdc.gov)
- Por YM , Mehta JS , Chua JL , Koh TH , Khor WB , Fong AC , Acanthamoeba keratitis associated with contact lens wear in Singapore. (cdc.gov)
- This can lead to painful eye conditions known as ocular surface diseases (OSDs) like dry eye syndrome and keratitis. (nanowerk.com)
- A corneal ulcer is a loss of corneal tissue, often associated with inflammation, and ulcerative keratitis is the general term for the group of disease processes leading to corneal ulceration, as well as the term for the inflammation that accompanies ulceration. (medscape.com)
- The annual incidence of microbial keratitis associated with contact lens use is approximately 2-4 infections per 10,000 users of soft contact lenses and 10-20 infections per 10,000 users of extended-wear contact lenses. (medscape.com)
- Infectious keratitis is significantly more common in contact lens wearers. (medscape.com)
- But there are a variety of ocular surface disease, including persistent epithelial defects, neurotrophic keratitis, trauma, pain patients, chronic management of chemical burns. (cybersight.org)
- Reports Of Fungal Keratitis Infections In Contact Lens Wearers. (yourlawyer.com)
- The FDA and CDC are continuing to investigate these case reports and identify specific behaviors that place contact lens wearers at increased risk for Fusarium keratitis . (yourlawyer.com)
- Additional information regarding the risk for fungal keratitis in contact lens users may be obtained by contacting Nancy Pressly by fax to 1-301-594-2968, email to [email protected] , or by correspondence addressed to the FDA Office of Surveillance and Biometrics (HFZ-510) at 1350 Piccard Drive, Rockville, Maryland, 20850. (yourlawyer.com)
- Need Legal Help Regarding Contact Lens Fungal Keratitis Infections? (yourlawyer.com)
Biomarkers3
- The eye contains a complex network of physiological information and biomarkers for monitoring disease and managing health , and ocular devices can be used to effectively perform point-of-care diagnosis and disease management . (bvsalud.org)
- This comprehensive review describes the target biomarkers and various diseases , including ophthalmic diseases, metabolic diseases , and neurological diseases , based on the physiological and anatomical background of the eye . (bvsalud.org)
- Potential Biomarkers for Allergic Conjunctival Diseases. (medscape.com)
Ophthalmic5
- Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management. (bvsalud.org)
- This review also includes the recent technologies utilized in eye -wearable medical devices and the latest trends in wearable ophthalmic devices , specifically smart contact lenses for the purpose of disease management . (bvsalud.org)
- Over the ensuing 40 years, further refinements in surgical technology and technique yielded additional reduction in incision size, sutureless wound closure, the development of ophthalmic viscoelastic agents, and intraocular lenses that now achieve unprecedented levels of visual function. (medscape.com)
- More and more commercial ophthalmic products incorporate EDOF (extended depth of focus) and multifocal technologies in contact and intra-ocular lenses to solve presbyopia. (sciencedaily.com)
- Ophthalmic cyclosporine is used to increase tear production in people with dry eye disease. (medlineplus.gov)
Ocular surface disease8
- The reserch has been published in Advanced Materials ( 'Nanozyme-Cosmetic Contact Lenses for Ocular Surface Disease Prevention' ). (nanowerk.com)
- Contact lenses are increasingly used for the management of ocular surface disease. (cybersight.org)
- My name is Angel Scanzera, and today we're going to be talking about therapeutic contact lenses in the management of ocular surface disease. (cybersight.org)
- It is becoming more common to use it for normal corneas, but it's most beneficial for patients with corneal irregularity, to help with the optics as well, and therapeutically, to help with ocular surface disease. (cybersight.org)
- And the goal is to have knowledge of when to consider a soft or scleral lens for the management of ocular surface disease. (cybersight.org)
- Protection from lid scarring, lagophthalmos, it helps with environmental factors such as dust and wind that can be irritating to a patient with ocular surface disease. (cybersight.org)
- Ocular surface disease is caused by conditions which affect eyelid function, tear production, or integrity of the corneal epithelium. (cybersight.org)
- this includes adequately treating any ocular surface disease, as well as minimizing warpage from contact lens wear. (aao.org)
Optometry4
- The Ocular Disease and Low Vision Rehabilitation Optometry Residency Program at the Lexington Veterans Affairs Health Care System is a 12-month (52-week) post-graduate clinical education program with three positions available. (va.gov)
- Dr. Colatrella is a fellow in the American Academy of Optometry, past Chair of its disease section and a founding chair of the Anterior Segment Section. (aaopt.org)
- He was the first of two Diplomates in Anterior Segment Disease of the American Academy of Optometry and a trustee on the American Academy of Optometry Board. (aaopt.org)
- It's time to see optometry through a new lens. (gettinghired.com)
Scleral8
- And the last one is the scleral lens. (cybersight.org)
- So the focus is going to be on soft and scleral lenses. (cybersight.org)
- Today we're going to go over some indications for contact lenses, soft lens parameters and fit assessment, scleral lens overview and fit assessment, and a case review. (cybersight.org)
- Mainly the idea is that when other treatments aren't sufficient, a soft and scleral lens should be considered. (cybersight.org)
- If the soft contact lens isn't sufficient, we might then consider the scleral lens. (cybersight.org)
- Residents have access to a retinal camera with fundus autofluorescence, anterior segment camera, OCT, Pentacam topographer, Humphrey and Goldmann visual field analyzers, specialty contact lens fitting sets including RGP and scleral lenses, and low vision fitting equipment. (va.gov)
- Rosenthal, who has a part-time appointment as assistant clinical professor of ophthalmology at the Medical School, is the developer of the Boston Scleral Lens, which literally allows the blind to see. (harvard.edu)
- Then he heard about Rosenthal's clinic on a radio talk show and came to Boston to see if Scleral Lenses could help. (harvard.edu)
Diagnosis4
- Advances in rare disease diagnosis, treatment development and care exemplify that a scientific, data-driven approach and ongoing stakeholder engagement-including, most importantly, patients and communities-can deliver enormous benefits and mitigate the harms, if not entirely eliminate them. (nih.gov)
- Residents will become proficient in ocular disease diagnosis and management, and comanaging systemic conditions that have ocular manifestations. (va.gov)
- It also potentially improves disease management and quality of life for AD patients, as an earlier diagnosis allows initiation of medication and treatment. (frontiersin.org)
- Dr. Ida Alul and Dr. Patricia Buehler wanted their patients to have a warm and welcoming environment, coupled with the latest technology available in the diagnosis and treatment of eye diseases. (cascadebusnews.com)
20182
- Ofri, R 2018, Diseases of the lens . (huji.ac.il)
- Dec. 12, 2018 Small imperfections in a wine glass or tiny creases in a contact lens can be tricky to make out, even in good light. (sciencedaily.com)
Prevalence1
- Additionally, the survey detailed a widespread prevalence of misinformation about contact lenses among consumers that could come back to harm their vision and eye health. (aoa.org)
Retinal3
- PVD is associated with the occurrence of several vitreoretinal diseases, such as rhegmatogenous retinal detachment and macular hole. (nih.gov)
- This study aims to explore risk factors for dislocation of IOL concurring with vitreoretinal disease, such as retinal detachment and macular hole, and to evaluate the efficacy and complications of surgical intervention for these abnormalities concurrently. (nih.gov)
- After introducing other ocular devices such as the retinal prosthesis , we further discuss the current challenges and potential possibilities of smart contact lenses . (bvsalud.org)
Conjunctival1
- Allergic conjunctival diseases (ACDs) are a group of ocular allergies that include allergic conjunctivitis, atopic keratoconjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis. (medscape.com)
Extended-wear contact lenses1
- Studies from the United Kingdom suggest that males who wear extended-wear contact lenses are at increased risk of forming a corneal ulcer. (medscape.com)
Drug-polymer film1
- A drug-polymer film on the lens is designed to slowly release medication over an extended period of time. (cnn.com)
Inflammation4
- In animal studies, these "nanozyme" contact lenses protected the eye surface from ROS and inflammation better than regular lenses. (nanowerk.com)
- But rats wearing nanozyme contact lenses showed much less damage and inflammation than animals without lenses or with regular lenses. (nanowerk.com)
- The colored lenses also reduced inflammation markers like TNF-alpha. (nanowerk.com)
- This is the name for a group of diseases that cause inflammation of the uvea. (webmd.com)
20213
- WHO European conference on tackling noncommunicable diseases through digital solutions, 14-15 December 2021, Moscow. (who.int)
- Mar. 10, 2021 New contact lens technology to help diagnose and monitor medical conditions may soon be ready for clinical trials. (sciencedaily.com)
- The authors dedicate special thanks in the publication to the SAXS team of Anton Paar, in particular Franz Pirolt (co-author, until 2021 at AP, note) and Heike Ehmann for the performance and technical support of SAXS experiments on intact eye lenses as well as the production of a special sample holder for eye lenses. (anton-paar.com)
Detection3
- One concrete example is the analysis of volatile organic metabolites in breath for the early detection of human disease, such as cancer or diabetes. (nanowerk.com)
- For many eye diseases early detection is critically important. (cascadebusnews.com)
- The establishment of the KIC will have a profound impact on the early detection and management of the disease. (vision2020australia.org.au)
Surgical1
- The latest guidelines for diagnosing and treating human lens diseses This full-color resource details the surgical and clinical aspects of human lens diseases to assure their successful diagnoses and treatment. (acco.be)
Smart Contact Lenses1
- Scientists are developing smart contact lenses embedded with miniscule mirrors that can magnify your vision by almost three times. (cnn.com)
Cognitive Impairment1
- Diagnostic investigations are limited, and physicians rely on clinical examination and exclusion of differential diagnoses that may cause cognitive impairment, such as depression, Parkinson's disease (PD), hypothyroidism, drug interactions, and vitamin deficiencies ( 6 ). (frontiersin.org)
Macular3
- Scientists are developing a telescopic contact lens to magnify human vision, which could help people with age-related macular degeneration. (cnn.com)
- It is hoped that the lens will improve the sight of people with age-related macular degeneration (AMD) - the third leading cause of blindness globally. (cnn.com)
- Our data shows that keratoconus poses a significant economic burden to the patients and that the quality of life in these patients is lower than those in patients with later onset eye diseases such as age-related macular degeneration or diabetic retinopathy, highlighting the significant long-term morbidity associated with keratoconus. (vision2020australia.org.au)
Corrective2
- Corrective lenses used to address presbyopia often lead to a halo effect. (sciencedaily.com)
- Treatment includes corrective glasses or contact lenses and using a patch or other strategies to make a child use the lazy eye. (webmd.com)
Contact lens options3
- What's more, eye care providers may be missing opportunities to discuss contact lens options with 2 out of every 3 patients. (aoa.org)
- Per April 2022 survey results published by the industry association representing contact lens and contact lens care product manufacturers, the Contact Lens Institute (CLI) , eye care providers (ECPs) missed vital opportunities to discuss contact lens options with as many as 2 out of every 3 patients. (aoa.org)
- We are having great success reducing people's need for reading glasses with contact lens options for distance and near," said Dr. Winter Lewis, the newest member of the Infocus team and a contact lens specialist. (cascadebusnews.com)
Therapeutic5
- This "two birds with one stone" approach would make lenses more useful while also making them inherently therapeutic. (nanowerk.com)
- These are mostly used for refractive purposes, but they can also be used for cosmesis, if we need a tinted lens for a patient with significant light sensitivity, and there are therapeutic reasons as well. (cybersight.org)
- I understand everyone's experience with therapeutic contact lenses is different, and it really depends on what options are available to you. (cybersight.org)
- So when should we consider therapeutic lenses? (cybersight.org)
- Are CB2 receptors a potential therapeutic target for neuroinflammatory diseases in humans? (hrc.govt.nz)
Symptoms3
- Your best defense is to have regular checkups , because eye diseases do not always have symptoms. (medlineplus.gov)
- Patients should be instructed to remove their lenses and contact their physician if they develop symptoms such as redness, pain, tearing, increased light sensitivity, blurry vision, discharge, or swelling. (yourlawyer.com)
- Imaging of the cornea has demonstrated that the thickness of the cornea at different locations is an important parameter for detecting subclinical keratoconus (disease that shows no clinical signs and symptoms) and that the cornea thins with increasing disease severity. (vision2020australia.org.au)
Disorders3
- The new NIH institute was the first government organization solely dedicated to research on human visual diseases and disorders. (nih.gov)
- In the months following infection, Black adults with severe disease were more likely than white adults to be diagnosed with diabetes and experience headaches, chest pain and joint pain, but less likely to have sleep disorders, cognitive problems, or fatigue. (nih.gov)
- She is the co-Chair of the Pediatric Eye Disease Investigator Group (PEDIG), a National Institutes of Health/National Eye Institute (NIH/NEI)-funded clinical research network comprised of 350+ pediatric optometrists and ophthalmologists who perform randomized clinical trials related to pediatric eye disorders. (aaopt.org)
Systemic1
- HighWire Lens: Interstitial lung disease in systemic sclerosis: where do we stand? (ersjournals.com)
Refractive2
- Microphakonit for Refractive Lens Exchange (MIRLEX): A New Technique. (acco.be)
- She has also served in leadership positions for the following large-scale NEI-funded studies: the Multi-Ethnic Pediatric Eye Disease Study (MEPEDS), Collaborative Longitudinal Evaluation of Refractive Error (CLEERE), Convergence Insufficiency Treatment Trial (CITT), and CITT-Attention & Reading Trial (CITT-ART). (aaopt.org)
Glasses5
- A key innovation with the lenses is the added ability to switch between magnified and regular vision through a complementary pair of glasses. (cnn.com)
- 11% recall contact lenses discussed as an occasional alternative for glasses. (aoa.org)
- 8% recall contact lenses discussed as a replacement for glasses. (aoa.org)
- These companies, of which direct-to-consumer retailers are often leading the charge, would like nothing more than to see the entire contact lens industry deregulated, allowing our patients to purchase contacts in the same way they purchase reading glasses. (aoa.org)
- For those who want to reduce their need for glasses and contact lenses, Dr. Alul offers state-of-the-art Customvue wavefront LASIK surgery, performed on-site at Infocus. (cascadebusnews.com)
Cornea thins1
- A former flight attendant, Pugh developed keratonconus, a disease in which the cornea thins out and becomes distorted, resulting in a gradual loss of sight. (harvard.edu)
Vision10
- Through research, collaboration and patient engagement, the rare diseases research field is paving the way to precision medicine's vision of using individualized data to match patients to therapies. (nih.gov)
- Often, there are no warning signs of diabetic eye disease or vision loss when damage first develops. (nih.gov)
- Over time, this disease can destroy the sharp vision in this part of the eye, leading to partial vision loss or blindness. (nih.gov)
- The lenses within our eyes are clear structures that help provide sharp vision-but they tend to become cloudy as we age. (nih.gov)
- From Genes to Disease Mechanisms -In the past 13 years, vision scientists have discovered many genes through new genomic techniques such as GWAS. (nih.gov)
- The ability to selectively magnify your vision makes the design of the glass-lens combination more suitable for daily life. (cnn.com)
- For 45 million Americans, contact lenses are their vision correction modality of choice. (aoa.org)
- Ectopia lentis, which happens when the lens of the eyes shifts, often leading to changes in vision. (nih.gov)
- In addition to primary eye care examinations, the residents provide low vision outpatient blind rehabilitation services to visually impaired Veterans, vision therapy services to combat Veterans with a history of polytrauma or traumatic brain injury, and medical contact lens fittings. (va.gov)
- He has taught contact lens fitting at the Mass. Eye and Ear Infirmary for many years, and from the beginning, he was struck by the way hard contacts could correct corneal distortions and dramatically improve the vision of those afflicted by this class of eye diseases. (harvard.edu)
Normal lens1
- Rats and rabbits wearing the nanozyme lenses were protected from corneal erosion compared to no lens or a normal lens. (nanowerk.com)
CLINICAL1
- During this live webinar, we will discuss lens options, risks and benefits, and clinical pearls to optimize patient outcomes. (cybersight.org)
20191
- Oct. 29, 2019 A team created the next generation of long-wave infrared plastic lenses. (sciencedaily.com)
Certain diseases1
- Therefore, Dr. Bourne's overarching research goal is to probe the neural substrate of certain diseases and conditions through the development lens. (nih.gov)
Invasive2
- Authors from the United Kingdom also report an 8 times higher incidence of corneal invasive event in contact lens wearers who sleep in contact lenses compared with wearers who use lenses only during the waking hours. (medscape.com)
- Tremblay led the optical design of the lens, which is based on a surgically implantable telescope currently used by some patients with AMD, but which is more invasive than a lens. (cnn.com)
Presbyopia2
- The collaboration will begin by using sensors and microelectronics within lenses to monitor glucose levels in diabetics and correct presbyopia. (cnn.com)
- Presbyopia is a result of natural aging and stems from a gradual thickening and decrease in elasticity of the lens inside the eye. (sciencedaily.com)
Dementia1
- According to the World Health Organization (WHO) Global Burden of Disease (2004), dementia is the second largest contributor leading to total number of years living with disability (YLD) in people aged 60 years or older at 13.5%, compared to heart disease (4.0%), stroke (4.4%), and cancer (2.2%) ( 1 ). (frontiersin.org)
Soft contact4
- Increased use of soft contact lenses in recent years has led to a dramatic rise in the occurrence of corneal ulcers, particularly due to Pseudomonas aeruginosa. (medscape.com)
- In our practice we start with a soft contact lens. (cybersight.org)
- In the US, about 76% of soft contact lens wearers are in a SiHy lens. (cybersight.org)
- Although the majority of patients remain to be interviewed, data for 30 cases thus far have revealed that 28 occurred in wearers of soft contact lenses. (yourlawyer.com)
Practice1
- In 1657, the physician William Harvey, who first discovered that blood circulates in the body, said that "[there is no] better way to advance the proper practice of medicine than to give our minds to the discovery of the usual law of nature by careful investigation of cases of rarer forms of disease. (nih.gov)
Keratoconus5
- Keratoconus is a disease in which the cornea (the clear front window of the eye) progressively thins and begins to bulge and protrude (see image below). (vision2020australia.org.au)
- In the early stages of the disease, keratoconus is managed with contact lenses. (vision2020australia.org.au)
- However, the procedure is only suitable for keratoconus patients at the early stages of disease, and long-term outcomes are not yet known. (vision2020australia.org.au)
- At the Centre for Eye Research Australia, my research team and I conducted the "Australian Study of Keratoconus" looking at over 400 patients with keratoconus to try to better understand the factors associated with the condition to develop strategies that can halt the disease progression or delay the time to first graft. (vision2020australia.org.au)
- Also we have previously confirmed the influence of genetics on keratoconus and now wish to identify genes directly implicated in disease. (vision2020australia.org.au)
Advanced Medica1
- 1 manufacturing plants for the associated product, Complete MoisturePlus (CMP) multipurpose contact lens solution (Advanced Medical Optics [AMO], Santa Ana, CA, USA). (cdc.gov)
Wore1
- Approximately 32 percent of respondents said that they wore contact lenses for no longer than the recommended one to three months while 17 percent said they never changed their lenses. (foxnews.com)
Wear4
- The survey found that people ages 18 to 34 were three times more likely to rely on social media for information about contact lens wear versus the total population, and 3 out of 5 adults sought alternative information sources, such as friends or online searches. (aoa.org)
- If you wear contact lenses, remove them before instilling cyclosporine eye drops and put them back in 15 minutes later. (medlineplus.gov)
- Of the contact lens users surveyed, 79 percent admitted to poor lens hygiene, including showering, swimming and sleeping in contacts that were not approved for overnight wear. (foxnews.com)
- So it could be used for disease states where the contact lens wear would be much shorter-perhaps steroids for uveitis or postop applications for antibiotics and pain medications. (aao.org)
Fungal1
- With the introduction of topical corticosteroid drugs in the treatment of eye disease, fungal corneal ulcers have become more common. (medscape.com)
Optical1
- A) Optical coherence tomography cross-section of lens. (aao.org)
Americans2
- Chances are you know someone with a rare disease-there are about 7,000 different rare diseases that affect an estimated 30 million Americans. (nih.gov)
- A recent American Optometric Association survey, which asked 1,000 adults aged 18 and older about their eye knowledge, found that most Americans lack common knowledge of eye diseases and proper contact lens hygiene. (foxnews.com)
Researchers6
- Now, researchers have developed specialized contact lenses containing nanoparticles that mimic antioxidant enzymes and continuously break down cell-damaging compounds called reactive oxygen species (ROS), harmful molecules that can damage our eyes. (nanowerk.com)
- The researchers then tested the nanozyme lenses in animals. (nanowerk.com)
- If the effects hold up in further studies, the researchers believe the nanozyme lenses could help prevent OSDs in patients at high risk due to their medications, environment or advancing age. (nanowerk.com)
- Researchers from Singapore have developed a contact lens patch type system to deliver drugs to the eye in order to combat various eye conditions. (europeanpharmaceuticalreview.com)
- The aim of the GRACE network was to perform gender-based research in cardiovascular disease, train new researchers, and ensure transparency and accessibility. (wikipedia.org)
- Moreover, the researchers found statistically significant evidence that a higher-dose contact lens was more effective than either a low-dose lens or standard topical therapy, said coauthor Joseph B. Ciolino, MD, a cornea subspecialist at Massachusetts Eye and Ear, in Boston. (aao.org)
Person's1
- The approach of characterizing and treating each person's disease as unique has come to be called "personalized" or "precision" medicine. (nih.gov)
Chronic3
Patients6
- We have so many innovative advancements in contact lens technology, and I'm always excited to share this information with patients. (aoa.org)
- We as a profession need to take the opportunity to gently educate our patients on the risks contact lenses can present if not worn properly, while also balancing our message to the tremendous benefit they can have on quality of life. (aoa.org)
- Educating our contact lens patients on this topic can take time, but just like educating on risks of disease, can pay dividends for their eye health down the road. (aoa.org)
- Of 26 patients who remembered which brand of lens products they used, all reported using a Bausch & Lomb ReNu solution or a generic brand manufactured by the same company. (yourlawyer.com)
- Because some patients had used additional contact lens solutions, the source of the fungus remains unclear. (yourlawyer.com)
- He provides routine eye care as well as contact lens fittings/services for patients. (yellowpages.com)