Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ. (1/2)
Acyl-CoA: cholesterol acyltransferase (ACAT) catalyzes the acylation of cholesterol to cholesteryl ester with long chain fatty acids and ACAT inhibition is a useful strategy for treating hypercholesterolemia or atherosclerosis. Pentacyclic triterpenes, ursolic acid (1), oleanolic acid (2), and betulinic acid (3) were isolated from the methanol extracts of the leaves of Lycopus lucidus TURCZ. by bioassay-guided fractionation. The structures of compounds 1-3 were elucidated by their spectroscopic data analysis. Among them, betulinic acid (3) exhibited more potent human ACAT-1 and ACAT-2 inhibitory activities with IC(50) values of 16.2+/-0.6 and 28.8+/-1.3 microM, respectively. (+info)Ethanol extract of Lycopus lucidus elicits positive inotropic effect via activation of Ca2+ entry and Ca2+ release in beating rabbit atria. (2/2)
(+info)'Lycopus' is a genus of primarily aquatic or semi-aquatic plants, also known as bugleweeds, which have been used in traditional medicine for their potential effects on heart rate and thyroid function, but it's important to note that these uses are not supported by rigorous scientific evidence and could interfere with certain medications.
"Lycopus" is a term that refers to a genus of plants in the mint family, also known as bugleweed. These plants are native to the Northern Hemisphere and have been used in traditional medicine for various purposes, such as treating heart conditions, calming nerves, and reducing inflammation.
However, it is important to note that "Lycopus" does not have a medical definition as a specific treatment or diagnosis. If you are seeking information about a medical condition or treatment, it is always best to consult with a qualified healthcare professional.
Virginicus1
- China, Japan, Korea, Russian Far East Lycopus virginicus L. - Virginia bugleweed/water-horehound - central + eastern United States Prof. Dr. Otto Wilhelm Thomé Flora von Deutschland, Österreich und der Schweiz 1885, Gera, Germany Kew World Checklist of Selected Plant Families USDA, NRCS (n.d. (wikipedia.org)
Europaeus4
- The plant's juice yields black dye, supposedly used by the Roma in Europe to tan their skin to mimic Egyptians, hence the common name of Gypsywort for Lycopus europaeus. (wikipedia.org)
- Extract of Lycopus europaeus L. reduces cardiac signs of hyperthyroidism in rats. (henriettes-herb.com)
- Gypsywort Lycopus europaeus - Common names gypsywort, gipsywort, bugleweed, European bugleweed and water horehound. (turfonline.co.uk)
- Gypsywort Lycopus europaeus seeds should be sown into the ground where they are to flower in autumn and covered with a thin layer of soil or compost. (turfonline.co.uk)
Americanus2
- Primorye region of Russia Lycopus americanus Muhl. (wikipedia.org)
- Lycopus americanus is an upright perennial that develops from elongated rhizomes, reaching a height of 3 to 5 feet. (mayernikkitchen.com)
Lamiaceae2
- Lycopus is a genus of herbaceous plants in the family Lamiaceae. (wikipedia.org)
- Part of the Lamiaceae family, bugleweed (Lycopus europeus) is native to Asia and Europe and has since spread to parts of North America. (josephflach.co.uk)
Asper1
- eastern United States Lycopus angustifolius Elliott - southeastern United States Lycopus asper Greene - rough bugleweed - western Canada, western + central United States Lycopus australis R.Br. (wikipedia.org)
Gypsywort1
- Australian Gypsywort - Australia Lycopus cavaleriei H.Lév. (wikipedia.org)
Uniflorus1
- Primorye region of Russia Lycopus uniflorus Michx. (wikipedia.org)
Rubellus1
- Traditional Chinese Medicine herb to make Lycopi rhizoma - China, Japan, Korea, Siberia, Russian Far East Lycopus rubellus Moench - central + eastern United States Lycopus × sherardii Steele - Quebec, Ontario, eastern United States Lycopus sichotensis Prob. (wikipedia.org)
Species2
- Lycopus antiquus has possibly been applied to more than one extinct species which were widely distributed in Europe and Siberia from the Miocene to the Pliocene. (wikipedia.org)
- Extant Lycopus species whose fruits most resemble L. antiquus, are the East Asian Lycopus lucidus and the Eurasian Lycopus exaltatus. (wikipedia.org)
Lucidus1
- Quebec Lycopus lucidus Turcz. (wikipedia.org)
Europeus1
- Lycopus europeus nelle febbri periodiche. (nih.gov)
Amplectens1
- ex W.P.C.Barton - American bugleweed - widespread across most of United States and Canada Lycopus amplectens Raf. (wikipedia.org)
Seeds1
- Fossil seeds of †Lycopus antiquus are known from the Middle Miocene strata of southern Russia, from the Miocene of Lower Lusatia, Germany, and from the Late Miocene strata of western Siberia and Ukraine. (wikipedia.org)
Dosage1
- Lycopus regulates thyroid function and dosage can be customized for each patient. (wellbeingshealth.com)
Heart3
- Lycopus extract and atenolol reduced the increased heart rate and blood pressure. (henriettes-herb.com)
- beta-Adrenoceptor density in heart tissue was significantly reduced by the Lycopus extract or the beta-blocking agent showing an almost equal efficacy. (henriettes-herb.com)
- Lycopus , &c. (heart). (abchomeopathy.com)
Works1
- Cos I know a few folks who might just need lycopus (or leonurus, which works pretty much the same way) for their high blood pressure. (henriettes-herb.com)
Western1
- naturalized in New Zealand and North America Lycopus exaltatus L.f. - central + eastern Europe, Siberia, Central Asia, Xinjiang, Caucasus, Western Himalayas Lycopus hirtellus Kom. (wikipedia.org)
Type1
- Vous trouverez également le type de panier à utiliser (dimensions) par rapport à l'acquisition d'une plante en godet, ainsi que le substrat qui lui convient le mieux. (passionbassin.com)