Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)
Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34)
Autosomal recessive syndrome characterized by hypogenesis or agenesis of CORPUS CALLOSUM. Clinical features include MENTAL RETARDATION; CRANIOFACIAL ABNORMALITIES; digital malformations, and growth retardation.
A subtype of GPI-anchored folate receptors that is expressed in PLACENTA and hematopoietic cells.

Complications of scoliosis surgery in children with myelomeningocele. (1/232)

The purpose of the present study was to evaluate whether the high incidence of complications in scoliosis surgery in myelomeningocele (MMC) could be attributed to the surgical technique and whether improvements were possible. Between 1984 and 1996, 77 patients with MMC and scoliosis were treated surgically. The clinical and radiological follow-up ranged from 1 to 10 years with a mean follow-up of 3.6 years. The mean age at time of surgery was 12 years 8 months. The average preoperative scoliosis measured 90.20 degrees and was corrected by 47%. The first four patients were stabilized with Harrington rods after anterior correction with a Zielke device (group 1). Twenty-five patients were operated only from posterior, using Cotrel-Dubousset (CD) instrumentation (group 2). In 13 patients an anterior release and discectomy was performed prior to CD posterior instrumentation (group 3). In 26 patients (group 4) this was combined with an anterior instrumentation. The 9 patients of group 5 had congenital vertebral malformations which made a special treatment necessary. Complications could be divided into hardware problems, such as implant failure, dislocation or pseudarthrosis, infections, anesthetic, and neurologic complications. Hardware problems were seen in 29% of all patients. More hardware problems were seen with the Harrington rod (75%) and after solitary posterior instrumentation (30%). The occurrence of pseudarthrosis was dependent on the surgical technique, the extent of posterior spondylodesis, and lumbosacral fusion. Patients with hardware problems had a mean loss of correction of 49% compared to 13% in the other patients. Depending on the different surgical techniques a loss of more than 30% was seen in 12-75% of the cases. Early postoperative shunt failure occurred in four cases; delayed failure - after more than 1 year - in three cases. One patient died within 1 day due to an acute hydrocephalus, another died after 2 1/2 years because of chronic shunt insufficiency with herniation. Wound problems were not dependent on the surgical technique, but on the extent of posterior spondylodesis and the lumbosacral fusion. Based on this analysis we believe our current practice of instrumented anterior and posterior fusion is justified. Further, we are very careful to check shunt function prior to acute correction of spinal deformity.  (+info)

Congenital kyphosis in myelomeningocele. The effect of cordotomy on bladder function. (2/232)

To determine the effect of cordotomy on the function of the bladder during surgical correction of congenital kyphosis in myelomeningocele, we reviewed 13 patients who had this procedure between 1981 and 1996. The mean age of the patients at operation was 8.9 years (3.7 to 16) and the mean follow-up was 4.8 years (1.3 to 10.8). Bladder function before and after operation was assessed clinically and quantitatively by urodynamics. The mean preoperative kyphosis was 117 degrees (52 to 175) and decreased to 49 degrees (1 to 89) immediately after surgery. At the latest follow-up, a mean correction of 52% had been achieved. Only one patient showed deterioration in bladder function after operation. Eight out of the nine patients who had urodynamic assessment had improvement in bladder capacity and compliance, and five showed an increase in urethral pressure. One patient developed a spastic bladder and required subsequent surgical intervention. Cordotomy, at or below the level of the kyphosis, allows excellent correction of the structural deformity.  (+info)

Migration of the abdominal catheter of a ventriculoperitoneal shunt into the scrotum--case report. (3/232)

A 3-day-old male neonate presented with migration of the ventriculoperitoneal (VP) shunt tip through the patent processus vaginalis resulting in scrotal hydrocele. The association of myelomeningocele with hydrocephalus may have been a predisposing factor in this rare complication. Development of scrotal swelling or hydrocele in a child with VP shunt should be recognized as a possible shunt complication.  (+info)

Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development. (4/232)

During axial skeleton development, the notochord is essential for the induction of the sclerotome and for the subsequent differentiation of cartilage forming the vertebral bodies and intervertebral discs. These functions are mainly mediated by the diffusible signaling molecule Sonic hedgehog. The products of the paired-box-containing Pax1 and the mesenchyme forkhead-1 (Mfh1) genes are expressed in the developing sclerotome and are essential for the normal development of the vertebral column. Here, we demonstrate that Mfh1 like Pax1 expression is dependent on Sonic hedgehog signals from the notochord, and Mfh1 and Pax1 act synergistically to generate the vertebral column. In Mfh1/Pax1 double mutants, dorsomedial structures of the vertebrae are missing, resulting in extreme spina bifida accompanied by subcutaneous myelomeningocoele, and the vertebral bodies and intervertebral discs are missing. The morphological defects in Mfh1/Pax1 double mutants strongly correlate with the reduction of the mitotic rate of sclerotome cells. Thus, both the Mfh1 and the Pax1 gene products cooperate to mediate Sonic hedgehog-dependent proliferation of sclerotome cells.  (+info)

Neural tube defects along the Texas-Mexico border, 1993-1995. (5/232)

In response to a 1991 anencephaly cluster in Cameron County, Texas, a surveillance and neural tube defect (NTD) recurrence prevention project for NTDs was implemented in the 14 Texas-Mexico border counties. For 1993-1995, NTD-affected pregnancies were identified at all gestational ages through active surveillance of multiple case-ascertainment sources. There were 87 cases of anencephaly, 96 cases of spina bifida, and 14 cases of encephalocele for respective rates of 6.4, 7.1, and 1.1 per 10,000 live births. Of the 197 NTD case-women, 93% were Hispanic. The overall, Hispanic, and Anglo NTD rates were, respectively, 14.6, 14.9, and 10.6 per 10,000 live births. The NTD rate for El Paso County (9.8 per 10,000), the most northwestern Texas county, was significantly lower (p = 0.001) than the aggregate rate for the rest of the Texas border (17.1 per 10,000). The overall Texas border rate was significantly higher (p < 0.001) than a recently estimated rate of 9.3 for California and minimally higher than a recently adjusted rate of 11.3 for the Metropolitan Atlanta Congenital Defects Program counties (p = 0.052), both of which now reflect all gestational ages. Of the 197 Texas border cases, 85% (168 cases) reached a gestational age of > or =20 weeks. Excluding cases of <20 weeks' gestation in the rate had a more marked effect on reducing the anencephaly rate (4.9 per 10,000) than the spina bifida rate (6.7 per 10,000). A country of birth was known for 153 (83%) of the 184 Hispanic case-women: 63% were born in Mexico; 24%, in Texas; and 11%, elsewhere in the United States. Rates for Mexico-born Hispanic women (15.1 per 10,000) were significantly higher than rates for United States-born Hispanic women (9.5 per 10,000) (p = 0.006).  (+info)

Spinal sonography and magnetic resonance imaging in patients with repaired myelomeningocele: comparison of modalities. (6/232)

The goals of this study were to evaluate the feasibility of using ultrasonography of the spine in the follow-up evaluation of patients with repaired myelomeningocele at birth and to compare sonography with the accepted modality of magnetic resonance imaging. Over a period of 4 years we performed 165 sonographic studies in 101 patients; 107 sonographic studies had MR imaging results for comparison. We collected our data prospectively. The quality of the sonograms was good in 110 of 129 studies, acceptable in 17 of 129, and poor in two of 129. The sonographic examinations failed in 33 of 165 studies (20%). Concordant information was obtained between ultrasonography and magnetic resonance imaging in the following percentage of studies: level of the distal end of the cord in 82%, position of the cord in the canal in 59%, presence of hydromyelia in 63%, cord duplication in 96%, adhesions in 16%, intradural mass in 37%, cord measurements in 85%, and dural sac measurements in 83%. At the lumbosacral level, we saw no cord pulsation in 57% of the studies in patients with cord adhesions and in 20% of those without adhesions. At the lower thoracic level, we saw no pulsation in 35% of the studies in patients with cord adhesions and in 7% of those without adhesions. Postoperative studies of cord release surgery in eight patients showed varied findings. We conclude that in those patients who have a spinal defect or interlaminar space allowing proper visualization of the lumbosacral spinal canal, ultrasound can provide fairly similar information to that obtained with magnetic resonance imaging of that area with no need for sedation and at a reduced cost. Ultrasonography seems more sensitive than magnetic resonance imaging in the detection of cord adhesions, which is particularly relevant in the diagnosis of tethering.  (+info)

Coexistent holoprosencephaly and Chiari II malformation. (7/232)

Chiari II malformations and holoprosencephaly have been considered to be brain malformations that differ with respect to teratogenic insult, embryologic mechanism, and morphology. We herein describe coexistent Chiari II malformation and holoprosencephaly that occurred in a viable infant. A review of the literature regarding Chiari II malformations and holoprosencephaly suggests that a disturbance to the mesenchyme in early embryologic life may be the cause of both malformations.  (+info)

Sagittal static imbalance in myelomeningocele patients: improvement in sitting ability by partial and total gibbus resection. (8/232)

The progression of kyphosis in myelomeningocele is independent of skeletal growth and requires early operative correction and stabilization to prevent a loss of sitting ability. In severe cases, only vertebrectomy makes it possible to achieve correction, stability and skin-closure without tension. In 14 patients with myelomeningocele gibbus, kyphectomy was performed, removing two vertebral bodies on average. The average kyphosis angle decreased from 128 degrees to 81 degrees, enabling most of the patients to participate again in social life by restoring wheelchair mobility. Nevertheless, a significantly higher complication rate was found compared to other correctional operations, lengthening the average hospital stay to 41 days. Special problems arose from trophic disorders of the skin and soft tissue and from the dystrophic muscles below the level of neural malfunction. In three cases, kyphosis reappeared cranial to the fused segments, requiring ventral stabilization. With respect to increasing kyphosis angle, an early intervention should be aimed at. A secondary operation can be necessary, if surgery is performed without taking care of the growth potential.  (+info)

Meningomyelocele is a type of neural tube defect that affects the development of the spinal cord and the surrounding membranes known as meninges. In this condition, a portion of the spinal cord and meninges protrude through an opening in the spine, creating a sac-like structure on the back. This sac is usually covered by skin, but it may be open in some cases.

Meningomyelocele can result in various neurological deficits, including muscle weakness, paralysis, and loss of sensation below the level of the lesion. It can also cause bladder and bowel dysfunction, as well as problems with sexual function. The severity of these symptoms depends on the location and extent of the spinal cord defect.

Early diagnosis and treatment are crucial for managing meningomyelocele and preventing further complications. Treatment typically involves surgical closure of the opening in the spine to protect the spinal cord and prevent infection. Physical therapy, occupational therapy, and other supportive care measures may also be necessary to help individuals with meningomyelocele achieve their full potential for mobility and independence.

Spinal dysraphism is a broad term used to describe a group of congenital malformations of the spine and spinal cord. These defects occur during embryonic development when the neural tube, which eventually forms the brain and spinal cord, fails to close properly. This results in an incomplete development or formation of the spinal cord and/or vertebral column.

There are two main categories of spinal dysraphism: open (also called exposed or overt) and closed (also called hidden or occult). Open spinal dysraphisms, such as myelomeningocele and myelocele, involve exposure of the spinal cord and/or its coverings through an opening in the back. Closed spinal dysraphisms, such as lipomyelomeningocele, tethered cord syndrome, and diastematomyelia, are more subtle and may not be visibly apparent at birth.

Symptoms of spinal dysraphism can vary widely depending on the type and severity of the defect. They may include motor and sensory impairments, bowel and bladder dysfunction, orthopedic deformities, and increased risk for neurological complications such as hydrocephalus (accumulation of fluid in the brain). Early diagnosis and intervention are crucial to optimize outcomes and minimize potential complications.

Acrocallosal syndrome is a rare genetic disorder characterized by the underdevelopment or absence of the corpus callosum (the part of the brain that connects the two hemispheres) and abnormalities of the fingers, toes, and face. The symptoms of this condition can vary widely in severity, but may include intellectual disability, developmental delays, seizures, weak muscle tone, abnormalities of the skull and facial bones, widely spaced eyes, a flat nasal bridge, a short nose with upturned nostrils, an open mouth with a highly arched roof, and a small jaw. In addition, individuals with Acrocallosal syndrome often have extra fingers or toes (polydactyly) and other skeletal abnormalities.

Acrocallosal syndrome is caused by mutations in the KIF7 gene, which provides instructions for making a protein that helps regulate the development and organization of cells in the body. Mutations in this gene are thought to disrupt the normal functioning of this protein, leading to the characteristic signs and symptoms of Acrocallosal syndrome. The disorder is inherited in an autosomal recessive manner, which means that an individual must inherit two copies of the mutated gene (one from each parent) in order to be affected.

Folate Receptor 2 (FR-α or FOLR2) is a protein that is encoded by the FOLR2 gene in humans. It is a member of the folate receptor family, which are proteins that bind and transport the vitamin folate (also known as vitamin B9) into cells.

FR-α is primarily expressed on the apical surface of polarized epithelial cells, including those found in the kidney, lung, and choroid plexus. It has a high affinity for folic acid and reduced folates, which it internalizes through receptor-mediated endocytosis. Once inside the cell, these compounds can be used in various metabolic processes, including DNA synthesis and repair.

FR-α has been studied as a potential target for cancer therapy because it is often overexpressed in certain types of cancer cells, such as ovarian and lung cancer. This overexpression can lead to an increased uptake of folate-conjugated drugs, which can then be selectively delivered to cancer cells while minimizing toxicity to normal tissues.

ISBN 978-0195042559 (1974) The practical management of meningomyelocele", University Park Press. ISBN 978-0839106395 Rasmussen ...
"Use of the Anal Plug in the Treatment of Fecal Incontinence in Patients With Meningomyelocele". Journal of Pediatric Nursing. ...
Meningomyelocele, on the other hand, is partially transilluminant as it contains nerve root fibres along with the CSF. Bright ...
... meningocele and meningomyelocele. Surgery is performed once symptomatic using transplatatine or endonasal route with the help ...
Baby Jane Doe was born on October 11, 1983, in Long Island, NY, with an open spinal column (meningomyelocele), hydrocephaly and ...
... meningomyelocele). Schoenwolf, Gary C. (2009). Human Embryology (4th ed.). Churchill Livingstone/Elsevier. ISBN 978-0443-06811- ...
... meningomyelocele, and porencephaly. When structural impairments are not observable or do not exist, neurological impairments ...
... also known as meningomyelocele, is the type of spina bifida that often results in the most severe complications and affects the ...
Meningocele Meningococcemia Meningoencephalocele Meningoencephalocele-arthrogryposis-hypoplastic thumb Meningomyelocele Mental ...
Spinal injuries Leprosy Peripheral nerve injury Diabetic neuropathy Tabes dorsalis Transverse myelitis Meningomyelocele ...
... enteritis Reifenstein syndrome Reinhardt-Pfeiffer syndrome Renal adysplasia dominant type Renal agenesis meningomyelocele ...
... and optic nerve hypoplasia Meningomyelocele (a spinal defect) Musculoskeletal and cutaneous Polydactyly (extra digits) ...
... meningomyelocele MeSH C10.500.680.800 - spinal dysraphism MeSH C10.500.680.800.730 - spina bifida cystica MeSH C10.500.680.800. ...
... meningomyelocele MeSH C16.131.666.680.800 - spinal dysraphism MeSH C16.131.666.680.800.730 - spina bifida cystica MeSH C16.131. ...
1907: Schwalbe and Gredig, pupils of German pathologist Julius Arnold, described four cases of meningomyelocele and alterations ...
Microcephaly Agenesis of the corpus callosum Meningomyelocele Lissencephaly Periventricular leukomalacia (PVL) Enlargement of ...
... Print Images (1) Contributors: Bo Hoon Lee MD, Jamie Adams MD, Richard L. Barbano MD, PhD. Other Resources ... Marked increases of meningomyelocele and spina bifida have been seen in Ethiopia due to lack of folic acid.. Diagnosis is often ... A meningomyelocele (also called myelomeningocele or spina bifida) is a herniation of the meninges and spinal cord through a ... Weakness and sensory loss below the level of the meningomyelocele may be partial or complete. Bowel and bladder involvement are ...
Home / Keyword meningomyelocele [2]. View: Monthly list ✔ Monthly list ✔ Monthly calendar ✔ Weekly list ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Bone changes in meningomyelocele. Tosovsky, V.; Strykal, F.; Kolikova, E. Tosovsky, V.; Strykal, F.; Kolikova, E. Less ...
Wilson P, Stewart J. Meningomyelocele (spina bifida). In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds ... Meningomyelocele; Spina bifida; Cleft spine; Neural tube defect (NTD); Birth defect - myelomeningocele ...
Dussa Vamshikrishna shares a case of trophic ulcer in woman of 24 with Meningomyelocele. ...
Bilateral vocal fold (vocal cord) immobility (BVFI) is a broad term that refers to all forms of reduced or absent movement of the vocal folds. Bilateral vocal fold (cord) paralysis (BVFP) refers to the neurologic causes of bilateral vocal fold immobility (BVFI) and specifically refers to the reduced or absent function of the vagus nerve or it...
PurposeTo propose an alternative method of surgical technique to address gibbus deformity in meningomyelocele with open wound ... Ilizarov kyphectomy technique in the management of the gibbus deformity with an open wound in meningomyelocele patients: a case ... Ilizarov kyphectomy technique in the management of the gibbus deformity with an open wound in meningomyelocele patients: a case ... To propose an alternative method of surgical technique to address gibbus deformity in meningomyelocele with open wound ...
ISBN 978-0195042559 (1974) The practical management of meningomyelocele", University Park Press. ISBN 978-0839106395 Rasmussen ...
Meningomyelocele. Autism Spectrum Disorder and Other Pervasive Developmental Disorders. Communication Impairment. Mental ...
Meningomyelocele/myelomeningocele (spina bifida). *Neural tube defects. *Obstructive epulis. *Omphalocele, including OEIS ...
Long-term outcome and complications of children born with meningomyelocele. Childs Nerv Syst. 1992 Mar. 8(2):92-6. [QxMD ... Bulbul A, Can E, Bulbul LG, Cömert S, Nuhoglu A. Clinical characteristics of neonatal meningomyelocele cases and effect of ... Moskowitz D, Shurtleff DB, Weinberger E, Loeser J, Ellenbogen R. Anatomy of the spinal cord in patients with meningomyelocele ... Cesarean section before the onset of labor and subsequent motor function in infants with meningomyelocele diagnosed antenatally ...
Adult meningo-myelocele Synthesis of treatment *The vesicourethral balance *Treatment alternatives for different types of ... Special considerations on meningo-myelocele *Neural tube defects: etiology, prevention, and prenatal diagnosis *Initial ... management of meningo-myelocele children * Intravesical electrical stimulation in new-born infants and children *Fecal ...
Meningomyelocele of lumbosacral spine. *Myelocele. *Myelocystocele. *Myelomeningocele. *Myelomeningocele without hydrocephalus ...
... meningomyelocele, hydrocephalus or any congenital cardiac abnormality. Active fetal therapy program ...
... fetal abnormalities associated with acitretin and/or etretinate administration have been reported including meningomyelocele; ...
However, CVS does not detect neural tube defects (spina bifida, meningomyelocele or anencephaly). Therefore, patients who opt ...
Nervous system abnormalities: neural tube defects (anencephaly, meningomyelocele), microcephaly, and hydrocephalus. *Renal ...
The Reality of Children and Adolescents with Meningomyelocele and Their Families, in the City of Belo Horizonte and Its ...
T polymorphism in a mother and her child with DS and cervical meningomyelocele. They found that the mother, who also had not ...
Meningomyelocele Medicin och livsvetenskap 100% * Pressure Medicin och livsvetenskap 49% * Wounds and Injuries Medicin och ...
There are retrospective postmarketing reports of findings consistent with neural tube defects, including meningomyelocele, all ...
Meningomyelocele 2 0 Ovarian Neoplasms 2 0 Cardiovascular Diseases 2 0 Neural Tube Defects 2 0 ...
... such as those with spinal cord injuries or children with meningomyelocele, a third alternative, intermittent catheterization, ...
  • One of the most common and severe neural tube defects is meningomyelocele (MM) resulting from failed closure of the caudal end of the neural tube. (nih.gov)
  • In reviewing the neural tube defects associated with valproate, Ornoy 2 notes that valproate is associated mainly with lumbosacral meningomyelocele (spina bifida aperta) at 10 to 20 times the rate found in the general population. (psychiatrist.com)
  • AChe), and hemoglobin F. It is possible to detect neural tube defects, including anencephaly, spina bifida, and meningomyelocele (though the use of amniocentesis to detect neural tube defects has been mostly superceded by a combination of the AFP test and high resolution detailed ultrasound). (parentingbanter.com)
  • A 13 year old male with a history of severe obstructive sleep apnea, meningomyelocele, Arnold-Chiari type II, hydrocephalus, and seizures underwent a positive airway pressure titration sleep study at our university sleep lab. (thoracic.org)
  • Neuropsychological profiles of children with aqueductal stenosis and spina bifida meningomyelocele. (chop.edu)
  • Diseases of your central nervous system, including Moebius syndrome and spina bifida (meningomyelocele). (diseasesdic.com)
  • DISCUSSION AND CONCLUSION: Cervical meningomyelocele is structurally and clinically different from thoracolumbar and lumbosacral meningomyelocele and has more favorable outcomes after surgery. (vantipderg.org)
  • The defect may be associated with a protrusion of the membrane covering the spinal cord (meninges) alone, called a meningocele, or with some neural elements, called a meningomyelocele. (nih.gov)
  • Association of folate receptor (FOLR1, FOLR2, FOLR3) and reduced folate carrier (SLC19A1) genes with meningomyelocele. (nih.gov)
  • Meningomyelocele" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • In these cases, the defect may occur if spinal disorders such as meningomyelocele are present in the infant during birth. (sitarambhartia.org)
  • 4 Months old baby, Suffering from meningomyelocele ( Congenital Tumor Disease of The Spinal Cord). (com.ng)
  • Suffering from meningomyelocele ( Congenital Tumor Disease of The Spinal Cord). (com.ng)
  • Our retrospective analysis of growth and pubertal development includes 109 children and adults with meningomyelocele (MMC) (52 M, 57 F) aged 3.2-21.0 years (median 8.9 years). (uni-luebeck.de)
  • 12. Outcome of meningomyelocele/lipomeningomyelocele in children of northern India. (nih.gov)
  • The study objective was to assess bone mass and muscular mass, as well as to analyze risk factors for osteoporosis and fractures in children with meningomyelocele based on densitometric examination. (osteoporoza.pl)
  • ISBN 978-0195042559 (1974) The practical management of meningomyelocele", University Park Press. (wikipedia.org)
  • This study presents one of the most extensive series of cervical meningomyelocele, reviewing its clinical features, surgical management, and management strategies. (vantipderg.org)
  • PURPOSE OF REVIEW: To review the advance of maternal--fetal surgery, the research of stem cell transplantation and tissue engineering in prenatal management of fetal meningomyelocele (fMMC). (afpm.org.my)
  • METHODS: A total of 520 spina bifida patients, 25 of whom were diagnosed with cervical meningomyelocele, from January 2010 to September 2022, were included in the study. (vantipderg.org)
  • This graph shows the total number of publications written about "Meningomyelocele" by people in this website by year, and whether "Meningomyelocele" was a major or minor topic of these publications. (umassmed.edu)
  • The patient was a 16 year old female who was born with a meningomyelocele. (virtualpediatrichospital.org)
  • Below are the most recent publications written about "Meningomyelocele" by people in Profiles. (umassmed.edu)