Middle Lobe Syndrome
Chyle
Improvement in right lung atelectasis (middle lobe syndrome) following administration of low-dose roxithromycin. (1/12)
Middle lobe syndrome is a distinct clinical entity characterized by right middle lobe atelectasis. Prompt diagnosis and initiation of medical therapy including the administration of antibiotics and the avoidance of irritating agents may be effective. However, abnormal shadows on chest radiography remain unchanged even when acute symptoms have disappeared, suggesting latent lesional inflammation or recurrence. We describe 2 cases of atelectasis in the middle lobe of the right lung which resolved completely after administration of low-dose roxithromycin. Thus, low-dose therapy with a macrolide could be of interest or some value in these cases, but it is too early to draw a definite conclusion. (+info)Role of infection in the middle lobe syndrome in asthma. (2/12)
Twenty one children with asthma aged 1.0-10.5 years (mean (SD) 3.3 (2.5) years) were admitted to the hospital to evaluate pulmonary right middle lobe or lingular collapse lasting one to 12 months (mean (SD) 4.4 (3.8) months). Seven children had mild asthma and were treated with inhaled beta 2 agonists as needed. Nine had moderate asthma treated with either sodium cromoglycate or slow release theophylline. Five had severe asthma treated with inhaled steroids. Each child underwent fibreoptic bronchoscopy under local anaesthesia and a bronchoalveolar lavage. Differential cell counts of the lavage fluid revealed predominance of neutrophils in 12 patients (57%). In nine of these patients cultures grew pathogenic bacteria, mainly Haemophilus influenzae and Streptococcus pneumoniae. There was no correlation between the severity of asthma and a positive bacterial culture. There was also no correlation between the duration of the right middle lobe collapse and a positive culture. We conclude that longstanding right middle lobe collapse in asthmatic children is often associated with bacterial infection. (+info)Lung cancer arising in association with middle lobe syndrome. (3/12)
Middle lobe syndrome, caused mainly by benign inflammatory diseases, such as chronic bronchitis and bronchiectasis, is manifested clinically as a chronic cough with sputum production. The prognosis associated with this syndrome is considered good in most cases which are caused by chronic inflammatory diseases. A patient who developed lung cancer in the course of long-term treatment for right middle lobe syndrome is described. A 63-year-old woman was admitted to our hospital with complaints of right iliac bone pain. She had been treated for chronic bronchitis and bronchiectasis associated with middle lobe syndrome for 16 years before admission. Work-up of a lung adenocarcinoma originating from the right middle lobe disclosed bone metastasis to the illium. Tumorigenesis in association with middle lobe syndrome has not yet been reported, but this first reported case suggests the need to be alert to the possibility. (+info)Bronchial anthracofibrosis and tuberculosis presenting as a middle lobe syndrome. (4/12)
(+info)Massive benign pericardial cyst presenting with simultaneous superior vena cava and middle lobe syndromes. (5/12)
(+info)Endobronchial tuberculosis presenting as right middle lobe syndrome: clinical characteristics and bronchoscopic findings in 22 cases. (6/12)
(+info)Chyloptysis with right middle lobe syndrome complicated postoperatively by chylothorax: an unusual cause of right middle lobe syndrome. (7/12)
Chyloptysis, in the context of middle lobe syndrome, and chylothorax are rare clinical entities. They are reported in the medical literature mostly as case reports, but never together in the same patient. The present report describes the case of a 34-year-old woman who presented with chyloptysis associated with recurrent right middle lobe syndrome since she was 20 years of age, and eventually underwent right middle lobectomy. A few weeks postoperatively, she developed a right-sided chylothorax, which was refractory to medical therapy, and was successfully treated with thoracic duct ligation. She has been symptom-free for two years postsurgery. (+info)Middle lobe syndrome in the left lower lobe in chronic obstructive pulmonary disease. (8/12)
(+info)Middle Lobe Syndrome is not a specific disease entity but rather a term used to describe a constellation of symptoms and radiological findings related to recurrent or persistent infection, inflammation, or abnormalities in the lung's middle lobe or lingula (the equivalent segment in the left lung). It is often associated with anatomical or functional abnormalities that affect the drainage of these segments, leading to recurrent or chronic accumulation of secretions and subsequent infection.
Symptoms may include persistent cough, sputum production, shortness of breath, chest pain, and sometimes fever. Diagnosis typically involves a combination of clinical evaluation, imaging studies (such as chest X-ray or CT scan), and occasionally bronchoscopy to evaluate the airways and obtain samples for culture or other tests. Treatment often involves antibiotics for infections, bronchodilators and mucolytic agents to help clear secretions, and sometimes interventions such as bronchoscopy or surgery to address any underlying anatomical abnormalities.
Chyle is a milky, slightly opaque fluid that is present in the lymphatic system. It is formed in the small intestine during the digestion of food, particularly fats. Chyle consists of emulsified fat droplets (chylomicrons), proteins, electrolytes, and lymphocytes suspended in a watery solution. It is transported through the lacteals in the villi of the small intestine into the cisterna chyli and then to the thoracic duct, where it empties into the left subclavian vein. From there, it mixes with blood and circulates throughout the body. Chyle formation plays a crucial role in fat absorption and transportation in the human body.
Bronchoscopy is a medical procedure that involves the examination of the inside of the airways and lungs with a flexible or rigid tube called a bronchoscope. This procedure allows healthcare professionals to directly visualize the airways, take tissue samples for biopsy, and remove foreign objects or secretions. Bronchoscopy can be used to diagnose and manage various respiratory conditions such as lung infections, inflammation, cancer, and bleeding. It is usually performed under local or general anesthesia to minimize discomfort and risks associated with the procedure.
A syndrome, in medical terms, is a set of symptoms that collectively indicate or characterize a disease, disorder, or underlying pathological process. It's essentially a collection of signs and/or symptoms that frequently occur together and can suggest a particular cause or condition, even though the exact physiological mechanisms might not be fully understood.
For example, Down syndrome is characterized by specific physical features, cognitive delays, and other developmental issues resulting from an extra copy of chromosome 21. Similarly, metabolic syndromes like diabetes mellitus type 2 involve a group of risk factors such as obesity, high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that collectively increase the risk of heart disease, stroke, and diabetes.
It's important to note that a syndrome is not a specific diagnosis; rather, it's a pattern of symptoms that can help guide further diagnostic evaluation and management.