Mucoid states characterized by the elevated deposition and accumulation of mucin (mucopolysaccharides) in dermal tissue. The fibroblasts are responsible for the production of acid mucopolysaccharides (GLYCOSAMINOGLYCANS) in the ground substance of the connective tissue system. When fibroblasts produce abnormally large quantities of mucopolysaccharides as hyaluronic acid, chondroitin sulfate, or heparin, they accumulate in large amounts in the dermis.

Cutaneous mucinosis and mastocytosis in a shar-pei. (1/11)

A 7-year-old shar-pei was presented because of a recurrent dermatologic condition. Skin biopsies revealed an idiopathic (primary) cutaneous mucinosis that initially responded to corticosteroids. The condition reappeared 2 years later and subsequent biopsies revealed a mast cell tumor in some of the skin sites previously diagnosed with mucinosis.  (+info)

Severe lung involvement in systemic scleromyxoedema: a highly unusual finding. (2/11)

Scleromyxoedema is a rare systemic disorder characterized by a lichenoid papular rash. Although scleromyxoedema can involve any organ, very few cases of pulmonary involvement have been reported. Moreover, there are no reports in the literature on treatment of this condition, especially with lung transplantation. The authors report a case of scleromyxoedema in a young man with neurological, skin and respiratory involvement, the latter being mainly characterized by pulmonary emphysema. Due to the serious respiratory compromise, and to the stability of the systemic lesions, a bilateral lung transplantation was performed with successful results at 4.5 yrs. In conclusion, lung transplantation may be required in patients with severe respiratory failure caused by scleromyxoedema.  (+info)

Papulonodular mucinosis in systemic lupus erythematosus. (3/11)

A 41-year-old man with systemic and serological manifestations of systemic lupus erythematosus presented with a diffuse eruption comprising annular plaques. Histopathology revealed diffuse deposition of mucin throughout the dermis, consistent with papulonodular mucinosis. This uncommon entity of unclear pathogenesis has been described in systemic lupus erythematosus, discoid lupus erythematosus, and subacute cutaneous lupus erythematosus.  (+info)

Pimecrolimus 1 percent cream and pulsed dye laser in treatment of a patient with reticular erythematous mucinosis syndrome. (4/11)

We report on the efficacy of twice daily application of pimecrolimus 1 percent cream in a 48-year-old woman with reticular erythematous mucinosis (REM) syndrome and compare its results with pulsed dye laser (PDL) on the other side of her chest and back. The patient was previously treated by hydroxychloroquine but only a fair response was observed. After application of 5 months of pimecrolimus, the lesions completely resolved and the result was comparable with the other side of her body treated by pulsed dye laser PDL. Topical pimecrolimus and pulsed dye laser appear to be effective and safe treatments for REM.  (+info)

Linear morphea with secondary mucinosis. (5/11)

 (+info)

Hereditary progressive mucinous histiocytosis: first report in a male patient. (6/11)

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Brown plaques on the lower back. (7/11)

A 12-year-old girl presented with a 2-year history of a 10 cm area of asymptomatic brown coalescent plaques of coalescent, linearly arranged papules on the lower back. No other physical or systemic abnormality was detected. Routine laboratory investigations, including thyroid function tests, were normal. The histopathological examination revealed hyperkeratosis, papillomatosis, and elongated rete ridges in the epidermis. On special staining (Alcian blue), mucin deposition was seen in the papillary dermis. The remaining dermis was normal. A diagnosis of Mucinous Nevus was made.  (+info)

Oral focal mucinosis: a rare case report of two cases. (8/11)

Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology. Clinically, it is most commonly found on the gingiva and presents as a painless, sessile or pedunculated mass of the same colour as the surrounding mucosa. Histologically, it is characterized by focal myxoid degeneration of connective tissue. OFM occurs predominantly in adults during the fourth and fifth decade of life, although it has been reported infrequently in children and adolescents. Its diagnosis mainly relies on histological analysis and the treatment involves complete surgical excision. Its recurrence is unreported. The aim of this report of two cases is to describe the clinical and histological presentation and subsequent management of OFM. The cause of OFM remains unknown. The cases presented in this report bring OFM to the attention of anatomical pathologists while considering the differential diagnosis of myxoid lesions of the oral cavity.  (+info)

Mucinoses are a group of cutaneous disorders characterized by the abnormal deposit of mucin in the dermis. Mucin is a complex sugar-protein substance that provides cushioning and lubrication to various tissues in the body. In mucinoses, an excess of mucin accumulates in the skin, leading to various clinical manifestations such as papules, nodules, plaques, or generalized swelling.

Mucinoses can be classified into two main categories: primary and secondary. Primary mucinoses are caused by genetic mutations that affect the production or degradation of mucin, while secondary mucinoses occur as a result of other underlying medical conditions, such as autoimmune disorders, infections, or neoplasms.

Examples of primary mucinoses include:

* Lichen myxedematosus (also known as papular mucinosis): characterized by multiple, firm, flesh-colored to yellowish papules and nodules, usually on the trunk and proximal extremities.
* Follicular mucinosis: a condition that affects hair follicles and is characterized by the accumulation of mucin in the follicular epithelium, leading to hair loss, itching, and inflammation.
* Scleromyxedema: a rare systemic disorder characterized by generalized thickening and hardening of the skin due to excessive deposition of mucin and collagen fibers.

Examples of secondary mucinoses include:

* Lupus erythematosus: an autoimmune disorder that can affect various organs, including the skin, and is characterized by the accumulation of mucin in the dermis.
* Dermatomyositis: another autoimmune disorder that affects the skin and muscles, and can also cause mucin deposition in the dermis.
* Rosai-Dorfman disease: a rare histiocytic disorder characterized by the accumulation of large, foamy histiocytes that contain mucin in the lymph nodes and other organs, including the skin.

The diagnosis of mucinoses is usually based on clinical examination, skin biopsy, and laboratory tests. Treatment depends on the underlying cause and may include topical or systemic medications, phototherapy, or surgical intervention.

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Mucinoses are a group of conditions caused by dermal fibroblasts producing abnormally large amounts of mucopolysaccharides. ...
Mucinoses, Rare diseases, Wikipedia medicine articles ready to translate, Wikipedia neurology articles ready to translate, ...
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Mucinoses, Connective tissue diseases, Autoimmune diseases, Disorders of fascia, Systemic connective tissue disorders). ...
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Mucinoses. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full ...
ISBN 978-0729540759; pbk{{cite book}}: CS1 maint: postscript (link) Rongioletti F, Rebora A (2007). "Mucinoses". In Bolognia JL ... CS1 maint: postscript, Articles with short description, Short description is different from Wikidata, Mucinoses, Thyroid, ...
Categories: Mucinoses Image Types: Photo, Illustrations, Video, Color, Black&White, PublicDomain, CopyrightRestricted 8 images ...
Mucinoses, deposition disorders, and connective tissue alterations / Franco Rongioletti, Jacqueline Granese, Jacqueline Junkins ...
Revencu, N., Boon, L. M., Mulliken, J. B., Enjolras, O., Cordisco, M. R., Burrows, P. E., Clapuyt, P., Hammer, F., Dubois, J., Baselga, E., Brancati, F., Carder, R., Quintal, J. M. C., Dallapiccola, B., Fischer, G., Frieden, I. J., Garzon, M., Harper, J., Johnson-Patel, J., Labrèze, C., & 14 othersMartorell, L., Paltiel, H. J., Pohl, A., Prendiville, J., Quere, I., Siegel, D. H., Valente, E. M., Van Hagen, A., Van Hest, L., Vaux, K. K., Vicente, A., Weibel, L., Chitayat, D. & Vikkula, M., Jul 2008, In: Human mutation. 29, 7, p. 959-965 7 p.. Research output: Contribution to journal › Article › peer-review ...
Rongioletti F et al (1998) Cutaneous mucinoses and HIV infection. Br J Dermatol 139:1077-1080. ... see also mucinoses). IgG1-Lambda is a 7S, papain-sensitive globulin (size approx. 100 kDa), which is strongly basic due to its ...
mucinoses. lymphoma. mucinosis, follicular. mucinoses. author_facet. Antônio de Pádua Marques da Fonseca. Sebastião Honório ... As mucinoses têm duas formas de apresentação: uma idiopática ou primária, e outra sintomática ou associada a diversos processos ... As mucinoses têm duas formas de apresentação: uma idiopática ou primária, e outra sintomática ou associada a diversos processos ... As mucinoses têm duas formas de apresentação: uma idiopática ou primária, e outra sintomática ou associada a diversos processos ...
Mucinoses , Escleromixedema , Humanos , Mucinoses/diagnóstico , Mucinoses/metabolismo , Mucinoses/patologia , Mucinas/ ... Using MFS, we showed that CD8+ T cells seem to be more involved in the production of mucin in FM than in dermal mucinoses, ... BACKGROUND: Primary cutaneous mucinoses (PCM) are rare diseases characterized by dermal or follicular mucin deposits. ... This finding was also significant in comparison with dermal mucinoses. CONCLUSION: Various cell types seem to contribute to ...
3. Rongioletti F, Ghigliotti G, Marchi R, Rebora A. Cutaneous mucinoses and HIV infection. Br J Dermatol. 1998;139:1077-1080.. ...
Cutaneous mucinoses. *Cutaneous porphyrias. *Cutaneous schistosomiasis *Cutaneous signs of child abuse. *Cutaneous small-vessel ...
Descritores em Ciências da Saúde
A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed ...
This graph shows the total number of publications written about "Cartilage Diseases" by people in this website by year, and whether "Cartilage Diseases" was a major or minor topic of these publications ...
A genetically heterogeneous, multifaceted disorder characterized by short stature, webbed neck, ptosis, skeletal malformations, hypertelorism, hormonal imbalance, CRYPTORCHIDISM, multiple cardiac abnormalities (most commonly including PULMONARY VALVE STENOSIS), and some degree of INTELLECTUAL DISABILITY. The phenotype bears similarities to that of TURNER SYNDROME that occurs only in females and has its basis in a 45, X karyotype abnormality. Noonan syndrome occurs in both males and females with a normal karyotype (46,XX and 46,XY). Mutations in a several genes (PTPN11, KRAS, SOS1, NF1 and RAF1) have been associated the the NS phenotype. Mutations in PTPN11 are the most common. LEOPARD SYNDROME, a disorder that has clinical features overlapping those of Noonan Syndrome, is also due to mutations in PTPN11. In addition, there is overlap with the syndrome called neurofibromatosis-Noonan syndrome due to mutations in NF1 ...
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynauds phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence ...
An asymptomatic, autosomal dominant trait in which pea-sized sclerotic spots, prominent in the metaphyseal area, are accompanied by unique cutaneous lesions. These are yellowish papules or plaques with increased elastin content. (From Cecil Textbook of Medicine, 19th ed, pp1434-35 ...
Dinsdale G, Peytrignet S, Moore T, Berks M, Roberts C, Manning J, Allen J, Anderson M, Cutolo M, Hesselstrand R, Howell K, Pizzorni C, Smith V, Sulli A, Wildt M, Taylor C, Murray A, Herrick AL. The assessment of nailfold capillaries: comparison of dermoscopy and nailfold videocapillaroscopy. Rheumatology (Oxford). 2018 06 01; 57(6):1115-1116 ...
This graph shows the total number of publications written about "Panniculitis" by people in this website by year, and whether "Panniculitis" was a major or minor topic of these publications ...
LocalizedAutoimmune DiseasesMucinosesVasculitisIdiopathic Interstitial PneumoniasMarfan SyndromePulmonary FibrosisWegener ...
Mucinoses. In: James WD, Elston DM, Treat JR, Rosenbach MA, Neuhaus IM, eds. Andrews Diseases of the Skin: Clinical ... Rongioletti F. Mucinoses. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 4th ed. Philadelphia, PA: Elsevier; 2018: ... Cutaneous mucinoses. In: Patterson JW, ed. Weedons Skin Pathology. 5th ed. Philadelphia, PA: Elsevier Limited; 2021:chap 14. ...
Mucinoses + Generalized myxedema in hypothyreosis + Pretibial myxedema + Reticular erythematous mucinosis + Papular mucinosis ...
Mucinoses* / genetics Actions. * Search in PubMed * Search in MeSH * Add to Search ...
The cutaneous mucinoses are a heterogeneous group of disorders in which an abnormal amount of mucin accumulates in the skin, ... Rongioletti F, Rebora A. Mucinoses. In: Bolognia JL, Jorizzo JL, Rapini RP, editors. Dermatology. 2 nd ed. Spain: Elsevier ...
... mucinoses on account online order metaxalone mr new york city of uncognisable exposing grained most erythrophagous thruout more ...
Mucinoses Preferred Term Term UI T052580. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1993). ... Mucinoses Preferred Concept UI. M0026583. Scope Note. Mucoid states characterized by the elevated deposition and accumulation ... Mucinoses. Tree Number(s). C17.300.550. Unique ID. D017520. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/D017520 ...
Mucinoses Preferred Term Term UI T052580. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1993). ... Mucinoses Preferred Concept UI. M0026583. Scope Note. Mucoid states characterized by the elevated deposition and accumulation ... Mucinoses. Tree Number(s). C17.300.550. Unique ID. D017520. RDF Unique Identifier. http://id.nlm.nih.gov/mesh/D017520 ...
Follicular Mucinoses. Follicular Mucinosis. Mucinoses, Follicular. Tree number(s):. C17.300.550.550. C17.800.329.937.122.550. ...
Mucinoses (0) * Neoplasms, Connective Tissue (0) * Noonan Syndrome (0) * Osteopoikilosis (0) * Panniculitis (0) ...
Mucinoses [C17.300.550]. *Mucopolysaccharidoses [C17.300.550.575]. *Mucopolysaccharidosis II [C17.300.550.575.645]. * ...
Chapter 9: Mucinoses Chapter 10: Seborrheic Dermatitis, Psoriasis, Recalcitrant Palmoplantar Eruptions, Pustular Dermatitis, ...
Mucinoses [C17.300.550]. *Scleromyxedema [C17.300.550.875]. Below are MeSH descriptors whose meaning is related to " ...
Mucinoses, Amyloides, and Depositions Disorders. 2:00PM - 2:20PM. Jordan P Talia, MD ...
PRIMARY CUTANEOUS MUCINOSES - A CLINICOPATHOLOGICAL REVIEW Para o diagnóstico diferencial entre as várias mucinoses é ainda ...
Cutaneous mucinoses refer to disorders with abnormal accumulation of mucin in the skin. Mucin is an amorphous material that is ... Cutaneous mucinoses could be primary or secondary. The latter is associated with systemic disorders such as autoimmune diseases ... Here, we report an adult female patient with trauma-induced cutaneous focal nodular mucinoses on left-sided scapular region. ...
4. Secondary dermal mucinoses are associated with autoimmune connective tissue disorders.. References ...
Global Mucinoses Management Market to reach nearly US$ 670 Million by 2033, growing at a 19.5% CAGR: Future Market Insights, ...
BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5-18 Years-United States, July 2021 - April 2022. Clin Infect Dis. 2023 02 08; 76(3):e90-e100 ...
As mucinoses têm duas formas de apresentação: uma idiopática ou primária, e outra sintomática ou associada a diversos processos ... Trauma-induced focal nodular mucinoses: A rare entity by: Gunjan Verma, et al. Published: (2018-01-01) ...
Mucinoses: 120*Mucopolysaccharidoses: 1486*Mucopolysaccharidosis VI: 155. *Nutritional and Metabolic Diseases: 2*Metabolic ...
Male Pattern T001481Male Pattern Baldness T001482Alopecia Areata T001483Alopecia Mucinosa T001484Follicular Mucinoses ...
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An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE ...
  • BACKGROUND: Primary cutaneous mucinoses (PCM) are rare diseases characterized by dermal or follicular mucin deposits. (bvsalud.org)
  • MUC1 expression in tissue histiocytes, fibroblasts, CD4+ and CD8+ T cells, and follicular epithelial cells of FM was significantly higher than the same cell types in the dermal mucinoses (p (bvsalud.org)
  • Using MFS, we showed that CD8+ T cells seem to be more involved in the production of mucin in FM than in dermal mucinoses, which could indicate that mucin in dermal and follicular epithelial mucinoses have different origins. (bvsalud.org)
  • 4. Secondary dermal mucinoses are associated with autoimmune connective tissue disorders. (eyepath.org.uk)