A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)
The front part of the hindbrain (RHOMBENCEPHALON) that lies between the MEDULLA and the midbrain (MESENCEPHALON) ventral to the cerebellum. It is composed of two parts, the dorsal and the ventral. The pons serves as a relay station for neural pathways between the CEREBELLUM to the CEREBRUM.
Excessive amount of sodium in the blood. (Dorland, 27th ed)
A condition resulting from the excessive retention of water with sodium depletion.
Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
The transference of a part of or an entire liver from one human or animal to another.
Death resulting from the presence of a disease in an individual, as shown by a single case report or a limited number of patients. This should be differentiated from DEATH, the physiological cessation of life and from MORTALITY, an epidemiological or statistical concept.
Works containing information articles on subjects in every field of knowledge, usually arranged in alphabetical order, or a similar work limited to a special field or subject. (From The ALA Glossary of Library and Information Science, 1983)
NATIONAL LIBRARY OF MEDICINE service for health professionals and consumers. It links extensive information from the National Institutes of Health and other reviewed sources of information on specific diseases and conditions.
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM.
Communication through a system of conventional vocal symbols.
Value of all final goods and services produced in a country in one year.
Mental activity, not predominantly perceptual, by which one apprehends some aspect of an object or situation based on past learning and experience.
An agency of the NATIONAL INSTITUTES OF HEALTH concerned with overall planning, promoting, and administering programs pertaining to advancement of medical and related sciences. Major activities of this institute include the collection, dissemination, and exchange of information important to the progress of medicine and health, research in medical informatics and support for medical library development.
A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
Disorders related to or resulting from abuse or mis-use of alcohol.
Habitual moderation in the indulgence of a natural appetite, especially but not exclusively the consumption of alcohol.
Substances interfering with the metabolism of ethyl alcohol, causing unpleasant side effects thought to discourage the drinking of alcoholic beverages. Alcohol deterrents are used in the treatment of alcoholism.
Child with one or more parents afflicted by a physical or mental disorder.

Does the extent of axonal loss and demyelination from chronic lesions in multiple sclerosis correlate with the clinical subgroup? (1/51)

OBJECTIVE: To determine non-invasively the relation between the degree of axonal loss and the extent of demyelination in chronic lesions visible on MRI in patients with different subgroups of clinically definite multiple sclerosis using (1)H magnetic resonance spectroscopy ((1)H MRS) and magnetisation transfer imaging (MT). Conventional MRI is unable to differentiate between the various pathological processes occurring in the multiple sclerosis lesion. There are, however, newer MR techniques which show promise in this respect. METHODS: (1)H MRS and MT were performed in 18 patients with clinically definite multiple sclerosis who had a wide range of disability and disease duration. RESULTS: A significant correlation was found between a reduction in the concentration of N-acetyl aspartate (NAA; an in vivo marker of axonal loss or dysfunction) and a reduction in MT ratio (a probable marker of demyelination) in patients who had entered the secondary progressive stage of the disease. Patients with minimal disability after a disease duration of greater than 10 years-so called benign multiple sclerosis-showed a relative preservation of NAA and MT. CONCLUSIONS: Because a reduction in MT seems to be a relative marker for demyelination and a reduction of NAA from chronic lesions is indicative of axonal loss, this study supports the hypothesis that demyelination and axonal loss occur in the same chronic multiple sclerosis lesions. In addition, the degree of axonal loss and demyelination correlates with clinical heterogeneity.  (+info)

Slowly progressive dystonia following central pontine and extrapontine myelinolysis. (2/51)

A 28-year-old woman was hospitalized with dysarthria and oro-mandibular and upper limb dystonia. Approximately 8 years prior to the current admission, the woman became severely hyponatremic due to traumatic subarachnoid hemorrhage-related SIADH. Brain MRIs showed a signal increase in the central pons, thalamus and striatum on T2 weighted images compatible with central pontine and extrapontine myelinolysis. From a few months after that event, dystonia progressed slowly over the subsequent 8 years. We speculate that the particular damage chiefly to the myelin structures by myelinolytic process may have caused an extremely slow plastic reorganization of the neural structures, giving rise to progressive dystonia.  (+info)

Treatment of severe hyponatremia: conventional and novel aspects. (3/51)

Hyponatremia is a frequent electrolyte disorder. A hyponatremia is called acute severe (<115 mM) when the duration has been <36 to 48 h. Such patients often have advanced symptoms as a result of brain edema. Acute severe hyponatremia is a medical emergency. It should be corrected rapidly to approximately 130 mM to prevent permanent brain damage. In contrast, in chronic severe hyponatremia (>4 to 6 d), there is no brain edema and symptoms are usually mild. In such patients, a number of authors have recommended a correction rate <0.5 mM/h to approximately 130 mM to minimize the risk of cerebral myelinolysis. Sometimes it is not possible to diagnose whether a severe hyponatremia is acute or chronic. In such cases, an initial imaging procedure is helpful in deciding whether rapid or slow correction should be prescribed. The modalities of treatment of severe hyponatremia have so far consisted of infusions of hypertonic saline plus fluid restriction. In the near future, vasopressin antagonists will become available. Preliminary experience has already demonstrated their efficiency of inducing a sustained water diuresis and a correction of hyponatremia.  (+info)

MR imaging of seven presumed cases of central pontine and extrapontine myelinolysis. (4/51)

MRI was performed in seven patients with presumed central pontine and extrapontine myelinolysis. The underlying diseases were diabetes, lung cancer, Wilson disease, trauma, alcoholism, renal insufficiency and hemodialysis. CPM was found in four cases (in two of them extrapontine lesions were considered as resulting from Wilson disease), CPM and EPM in three patients. The localization of extrapontine changes included cerebellum, cerebral peduncles, caudate and lentiform nuclei, internal capsules, white matter and cortex of the cerebrum.  (+info)

Decreased diffusion in central pontine myelinolysis. (5/51)

Two patients with central pontine myelinolysis (CPM) were studied with diffusion-weighted MR imaging 1 week after onset of tetraplegia. In both patients, affected white matter showed hyperintensity on diffusion-weighted images associated with a decrease in apparent diffusion coefficient (ADC) values. In one patient studied serially, ADC values normalized by 3 weeks after tetraplegia. Early in the clinical course, diagnosis of CPM can sometimes be difficult. Hyperintensity on diffusion-weighted images may therefore have diagnostic utility. Decreased lesional ADC values support the notion that CPM is a consequence of relative intracellular hypotonicity.  (+info)

Serial magnetic resonance imaging of central pontine myelinolysis. (6/51)

Central Pontine Myelinolysis (CPM) is a rare neurologic complication after liver transplantation. The true incidence of CPM after orthotopic liver transplantation remains an estimate. However, with the introduction of magnetic resonance imaging, early recognition became feasible. In this report, we present a case of rapid resolution of CPM followed by serial magnetic resonance imaging scans.  (+info)

A 47-year-old alcoholic man with progressive abnormal gait. (7/51)

Central pontine myelinolysis should be considered in the differential diagnosis of a patient with a history of alcoholism and malnutrition presenting with ataxia, regardless of serum sodium values. T2-weighted images are the most sensitive imaging technique, but changes may not be evident for weeks after the insult, and in addition, the insult may not be known. Supportive care is important to prevent complications, but no treatment has been found to be effective in treating the illness. Patient outcomes vary considerably and are difficult to predict.  (+info)

Central pontine myelinolysis associated with hypokalaemia in anorexia nervosa. (8/51)

A 31-year-old man was admitted to hospital with of anorexia, binge eating, and self induced vomiting. On admission, he showed a pronounced low weight and disturbance of the body image and was diagnosed as having anorexia nervosa. In addition, electrolyte abnormalities, mainly hypokalaemia, and increased serum renin and aldosterone concentrations were recorded, suggesting pseudo-Bartter syndrome as a complication. Under frequent monitoring of the serum potassium and sodium concentrations, serum electrolytes were gradually corrected, but brain magnetic resonance imaging revealed reversible central pontine myelinolysis (CPM). Although attention has been mainly paid to the association of CPM with rapid correction of hyponatraemia and abnormal osmolality, this case report strongly suggested the involvement of hypokalaemia in the pathogenesis of CPM.  (+info)

Central pontine myelinolysis (CPM) is a neurological disorder that results from the damage to the myelin sheath in the central pons region of the brainstem. Myelin is the fatty substance that insulates and protects nerve fibers, allowing for the efficient transmission of electrical signals.

In CPM, the myelin sheath in the center of the pons area becomes damaged or destroyed due to various factors, most commonly rapid correction of hyponatremia (low sodium levels in the blood). This rapid correction can lead to an osmotic shift of water from inside the cells to outside, causing swelling and damage to the myelin sheath.

CPM is characterized by the development of symmetrical lesions in the central pons region, which can result in a range of neurological symptoms, including weakness or paralysis of muscles, difficulty swallowing, speech impairment, and altered levels of consciousness. In severe cases, CPM can lead to coma, respiratory failure, and even death.

It's important to note that the management of CPM involves preventing further damage to the myelin sheath by avoiding rapid correction of hyponatremia and providing supportive care for the neurological symptoms. Currently, there is no specific treatment for CPM, and recovery can be slow and incomplete.

Hyponatremia is a condition characterized by abnormally low sodium levels in the blood, specifically levels less than 135 mEq/L. Sodium is an essential electrolyte that helps regulate water balance in and around your cells and plays a crucial role in nerve and muscle function. Hyponatremia can occur due to various reasons, including certain medical conditions, medications, or excessive water intake leading to dilution of sodium in the body. Symptoms may range from mild, such as nausea, confusion, and headache, to severe, like seizures, coma, or even death in extreme cases. It's essential to seek medical attention if you suspect hyponatremia, as prompt diagnosis and treatment are vital for a favorable outcome.

The pons is a part of the brainstem that lies between the medulla oblongata and the midbrain. Its name comes from the Latin word "ponte" which means "bridge," as it serves to connect these two regions of the brainstem. The pons contains several important structures, including nerve fibers that carry signals between the cerebellum (the part of the brain responsible for coordinating muscle movements) and the rest of the nervous system. It also contains nuclei (clusters of neurons) that help regulate various functions such as respiration, sleep, and facial movements.

Hypernatremia is a medical condition characterized by an abnormally high concentration of sodium (na+) in the blood, specifically a serum sodium level greater than 145 mEq/L. Sodium is an essential electrolyte that helps regulate water balance in and around your cells. It's crucial for many body functions, including the maintenance of blood pressure, regulation of nerve and muscle function, and regulation of fluid balance.

Hypernatremia typically results from a deficit of total body water relative to solute, which can be caused by decreased water intake, increased water loss, or a combination of both. Common causes include dehydration due to severe vomiting or diarrhea, excessive sweating, burns, kidney diseases, and the use of certain medications such as diuretics.

Symptoms of hypernatremia can range from mild to severe and may include thirst, muscle weakness, lethargy, irritability, confusion, seizures, and in extreme cases, coma or even death. Treatment typically involves correcting the underlying cause and gradually rehydrating the individual with intravenous fluids to restore normal sodium levels.

Medical Definition of Water Intoxication:

Water intoxication, also known as hyponatremia, is a condition that occurs when an individual consumes water in such large quantities that the body's electrolyte balance is disrupted. This results in an abnormally low sodium level in the blood (hyponatremia), which can cause symptoms ranging from mild to severe, including nausea, headache, confusion, seizures, coma, and even death in extreme cases. It's important to note that water intoxication is rare and typically only occurs in situations where large amounts of water are consumed in a short period of time, such as during endurance sports or when someone is trying to intentionally harm themselves.

Demyelinating diseases are a group of disorders that are characterized by damage to the myelin sheath, which is the protective covering surrounding nerve fibers in the brain, optic nerves, and spinal cord. Myelin is essential for the rapid transmission of nerve impulses, and its damage results in disrupted communication between the brain and other parts of the body.

The most common demyelinating disease is multiple sclerosis (MS), where the immune system mistakenly attacks the myelin sheath. Other demyelinating diseases include:

1. Acute Disseminated Encephalomyelitis (ADEM): An autoimmune disorder that typically follows a viral infection or vaccination, causing widespread inflammation and demyelination in the brain and spinal cord.
2. Neuromyelitis Optica (NMO) or Devic's Disease: A rare autoimmune disorder that primarily affects the optic nerves and spinal cord, leading to severe vision loss and motor disability.
3. Transverse Myelitis: Inflammation of the spinal cord causing damage to both sides of one level (segment) of the spinal cord, resulting in various neurological symptoms such as muscle weakness, numbness, or pain, depending on which part of the spinal cord is affected.
4. Guillain-Barré Syndrome: An autoimmune disorder that causes rapid-onset muscle weakness, often beginning in the legs and spreading to the upper body, including the face and breathing muscles. It occurs when the immune system attacks the peripheral nerves' myelin sheath.
5. Central Pontine Myelinolysis (CPM): A rare neurological disorder caused by rapid shifts in sodium levels in the blood, leading to damage to the myelin sheath in a specific area of the brainstem called the pons.

These diseases can result in various symptoms, such as muscle weakness, numbness, vision loss, difficulty with balance and coordination, and cognitive impairment, depending on the location and extent of the demyelination. Treatment typically focuses on managing symptoms, modifying the immune system's response, and promoting nerve regeneration and remyelination when possible.

Dystonia is a neurological movement disorder characterized by involuntary muscle contractions, leading to repetitive or twisting movements. These movements can be painful and may affect one part of the body (focal dystonia) or multiple parts (generalized dystonia). The exact cause of dystonia varies, with some cases being inherited and others resulting from damage to the brain. Treatment options include medications, botulinum toxin injections, and deep brain stimulation surgery.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Brain diseases, also known as neurological disorders, refer to a wide range of conditions that affect the brain and nervous system. These diseases can be caused by various factors such as genetics, infections, injuries, degeneration, or structural abnormalities. They can affect different parts of the brain, leading to a variety of symptoms and complications.

Some examples of brain diseases include:

1. Alzheimer's disease - a progressive degenerative disorder that affects memory and cognitive function.
2. Parkinson's disease - a movement disorder characterized by tremors, stiffness, and difficulty with coordination and balance.
3. Multiple sclerosis - a chronic autoimmune disease that affects the nervous system and can cause a range of symptoms such as vision loss, muscle weakness, and cognitive impairment.
4. Epilepsy - a neurological disorder characterized by recurrent seizures.
5. Brain tumors - abnormal growths in the brain that can be benign or malignant.
6. Stroke - a sudden interruption of blood flow to the brain, which can cause paralysis, speech difficulties, and other neurological symptoms.
7. Meningitis - an infection of the membranes surrounding the brain and spinal cord.
8. Encephalitis - an inflammation of the brain that can be caused by viruses, bacteria, or autoimmune disorders.
9. Huntington's disease - a genetic disorder that affects muscle coordination, cognitive function, and mental health.
10. Migraine - a neurological condition characterized by severe headaches, often accompanied by nausea, vomiting, and sensitivity to light and sound.

Brain diseases can range from mild to severe and may be treatable or incurable. They can affect people of all ages and backgrounds, and early diagnosis and treatment are essential for improving outcomes and quality of life.

Sodium is an essential mineral and electrolyte that is necessary for human health. In a medical context, sodium is often discussed in terms of its concentration in the blood, as measured by serum sodium levels. The normal range for serum sodium is typically between 135 and 145 milliequivalents per liter (mEq/L).

Sodium plays a number of important roles in the body, including:

* Regulating fluid balance: Sodium helps to regulate the amount of water in and around your cells, which is important for maintaining normal blood pressure and preventing dehydration.
* Facilitating nerve impulse transmission: Sodium is involved in the generation and transmission of electrical signals in the nervous system, which is necessary for proper muscle function and coordination.
* Assisting with muscle contraction: Sodium helps to regulate muscle contractions by interacting with other minerals such as calcium and potassium.

Low sodium levels (hyponatremia) can cause symptoms such as confusion, seizures, and coma, while high sodium levels (hypernatremia) can lead to symptoms such as weakness, muscle cramps, and seizures. Both conditions require medical treatment to correct.

Liver transplantation is a surgical procedure in which a diseased or failing liver is replaced with a healthy one from a deceased donor or, less commonly, a portion of a liver from a living donor. The goal of the procedure is to restore normal liver function and improve the patient's overall health and quality of life.

Liver transplantation may be recommended for individuals with end-stage liver disease, acute liver failure, certain genetic liver disorders, or liver cancers that cannot be treated effectively with other therapies. The procedure involves complex surgery to remove the diseased liver and implant the new one, followed by a period of recovery and close medical monitoring to ensure proper function and minimize the risk of complications.

The success of liver transplantation has improved significantly in recent years due to advances in surgical techniques, immunosuppressive medications, and post-transplant care. However, it remains a major operation with significant risks and challenges, including the need for lifelong immunosuppression to prevent rejection of the new liver, as well as potential complications such as infection, bleeding, and organ failure.

A fatal outcome is a term used in medical context to describe a situation where a disease, injury, or illness results in the death of an individual. It is the most severe and unfortunate possible outcome of any medical condition, and is often used as a measure of the severity and prognosis of various diseases and injuries. In clinical trials and research, fatal outcome may be used as an endpoint to evaluate the effectiveness and safety of different treatments or interventions.

An encyclopedia is a comprehensive reference work containing articles on various topics, usually arranged in alphabetical order. In the context of medicine, a medical encyclopedia is a collection of articles that provide information about a wide range of medical topics, including diseases and conditions, treatments, tests, procedures, and anatomy and physiology. Medical encyclopedias may be published in print or electronic formats and are often used as a starting point for researching medical topics. They can provide reliable and accurate information on medical subjects, making them useful resources for healthcare professionals, students, and patients alike. Some well-known examples of medical encyclopedias include the Merck Manual and the Stedman's Medical Dictionary.

MedlinePlus is not a medical term, but rather a consumer health website that provides high-quality, accurate, and reliable health information, written in easy-to-understand language. It is produced by the U.S. National Library of Medicine, the world's largest medical library, and is widely recognized as a trusted source of health information.

MedlinePlus offers information on various health topics, including conditions, diseases, tests, treatments, and wellness. It also provides access to drug information, medical dictionary, and encyclopedia, as well as links to clinical trials, medical news, and patient organizations. The website is available in both English and Spanish and can be accessed for free.

The brain is the central organ of the nervous system, responsible for receiving and processing sensory information, regulating vital functions, and controlling behavior, movement, and cognition. It is divided into several distinct regions, each with specific functions:

1. Cerebrum: The largest part of the brain, responsible for higher cognitive functions such as thinking, learning, memory, language, and perception. It is divided into two hemispheres, each controlling the opposite side of the body.
2. Cerebellum: Located at the back of the brain, it is responsible for coordinating muscle movements, maintaining balance, and fine-tuning motor skills.
3. Brainstem: Connects the cerebrum and cerebellum to the spinal cord, controlling vital functions such as breathing, heart rate, and blood pressure. It also serves as a relay center for sensory information and motor commands between the brain and the rest of the body.
4. Diencephalon: A region that includes the thalamus (a major sensory relay station) and hypothalamus (regulates hormones, temperature, hunger, thirst, and sleep).
5. Limbic system: A group of structures involved in emotional processing, memory formation, and motivation, including the hippocampus, amygdala, and cingulate gyrus.

The brain is composed of billions of interconnected neurons that communicate through electrical and chemical signals. It is protected by the skull and surrounded by three layers of membranes called meninges, as well as cerebrospinal fluid that provides cushioning and nutrients.

Speech is the vocalized form of communication using sounds and words to express thoughts, ideas, and feelings. It involves the articulation of sounds through the movement of muscles in the mouth, tongue, and throat, which are controlled by nerves. Speech also requires respiratory support, phonation (vocal cord vibration), and prosody (rhythm, stress, and intonation).

Speech is a complex process that develops over time in children, typically beginning with cooing and babbling sounds in infancy and progressing to the use of words and sentences by around 18-24 months. Speech disorders can affect any aspect of this process, including articulation, fluency, voice, and language.

In a medical context, speech is often evaluated and treated by speech-language pathologists who specialize in diagnosing and managing communication disorders.

I'm sorry for any confusion, but "Gross Domestic Product" (GDP) is an economic term, not a medical one. GDP is the total monetary or market value of all the finished goods and services produced within a country's borders in a specific time period. It serves as a comprehensive measure of a nation’s overall economic activity.

If you have any medical questions or terms you would like defined, I would be happy to help!

I'm sorry for any confusion, but "thinking" is not a term that has a specific medical definition. It is a cognitive process, which is a general term used to describe various mental activities related to perception, reasoning, memory, attention, language use, learning, and problem-solving. These processes are studied across many fields, including psychology, neuroscience, philosophy, and linguistics.

If you're looking for medical definitions of cognitive processes or conditions that affect cognition, I'd be happy to help! Please provide more details.

Alcoholism is a chronic and often relapsing brain disorder characterized by the excessive and compulsive consumption of alcohol despite negative consequences to one's health, relationships, and daily life. It is also commonly referred to as alcohol use disorder (AUD) or alcohol dependence.

The diagnostic criteria for AUD include a pattern of alcohol use that includes problems controlling intake, continued use despite problems resulting from drinking, development of a tolerance, drinking that leads to risky behaviors or situations, and withdrawal symptoms when not drinking.

Alcoholism can cause a wide range of physical and psychological health problems, including liver disease, heart disease, neurological damage, mental health disorders, and increased risk of accidents and injuries. Treatment for alcoholism typically involves a combination of behavioral therapies, medications, and support groups to help individuals achieve and maintain sobriety.

'Alcohol drinking' refers to the consumption of alcoholic beverages, which contain ethanol (ethyl alcohol) as the active ingredient. Ethanol is a central nervous system depressant that can cause euphoria, disinhibition, and sedation when consumed in small to moderate amounts. However, excessive drinking can lead to alcohol intoxication, with symptoms ranging from slurred speech and impaired coordination to coma and death.

Alcohol is metabolized in the liver by enzymes such as alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). The breakdown of ethanol produces acetaldehyde, a toxic compound that can cause damage to various organs in the body. Chronic alcohol drinking can lead to a range of health problems, including liver disease, pancreatitis, cardiovascular disease, neurological disorders, and increased risk of cancer.

Moderate drinking is generally defined as up to one drink per day for women and up to two drinks per day for men, where a standard drink contains about 14 grams (0.6 ounces) of pure alcohol. However, it's important to note that there are no safe levels of alcohol consumption, and any level of drinking carries some risk to health.

Ethanol is the medical term for pure alcohol, which is a colorless, clear, volatile, flammable liquid with a characteristic odor and burning taste. It is the type of alcohol that is found in alcoholic beverages and is produced by the fermentation of sugars by yeasts.

In the medical field, ethanol is used as an antiseptic and disinfectant, and it is also used as a solvent for various medicinal preparations. It has central nervous system depressant properties and is sometimes used as a sedative or to induce sleep. However, excessive consumption of ethanol can lead to alcohol intoxication, which can cause a range of negative health effects, including impaired judgment, coordination, and memory, as well as an increased risk of accidents, injuries, and chronic diseases such as liver disease and addiction.

According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), alcohol-related disorders are a category of mental disorders defined by a problematic pattern of alcohol use that leads to clinically significant impairment or distress. The disorders include:

1. Alcohol Use Disorder (AUD): A chronic relapsing brain disorder characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. AUD can be mild, moderate, or severe, and recovery is possible regardless of severity. The symptoms include problems controlling intake of alcohol, continued use despite problems resulting from drinking, development of a tolerance, drinking that leads to risky situations, or withdrawal symptoms when not drinking.
2. Alcohol Intoxication: A state of acute impairment in mental and motor function caused by the recent consumption of alcohol. The symptoms include slurred speech, unsteady gait, nystagmus, impaired attention or memory, stupor, or coma. In severe cases, it can lead to respiratory depression, hypothermia, or even death.
3. Alcohol Withdrawal: A syndrome that occurs when alcohol use is heavily reduced or stopped after prolonged and heavy use. The symptoms include autonomic hyperactivity, increased hand tremor, insomnia, nausea or vomiting, transient visual, tactile, or auditory hallucinations or illusions, psychomotor agitation, anxiety, and grand mal seizures.
4. Other Alcohol-Induced Disorders: These include alcohol-induced sleep disorder, alcohol-induced sexual dysfunction, and alcohol-induced major neurocognitive disorder.

It is important to note that alcohol use disorders are complex conditions that can be influenced by a variety of factors, including genetics, environment, and personal behavior. If you or someone you know is struggling with alcohol use, it is recommended to seek professional help.

In the context of medicine and health, "temperance" refers to moderation or self-restraint in the consumption of potentially harmful substances, particularly alcohol. It promotes a balanced lifestyle that avoids excessive habits, such as overeating, substance abuse, or any other activities that could negatively impact one's health.

However, it is important to note that "temperance" itself is not a medical term per se but has been used in various historical and social contexts related to health promotion and disease prevention.

Alcohol deterrents, also known as alcohol deterrent devices or ignition interlock devices, are breathalyzer devices that are installed in vehicles to prevent a driver from starting the vehicle if their blood alcohol concentration (BAC) is above a certain limit. These devices are often used as a condition of license reinstatement for individuals who have been convicted of drunk driving or other alcohol-related offenses.

The driver must blow into the device, and if their BAC is above the programmed limit, the vehicle will not start. Some devices also require periodic rolling retests while the vehicle is in motion to ensure that the driver remains sober throughout the trip. The use of alcohol deterrents has been shown to reduce recidivism rates among drunk drivers and improve overall road safety.

There is no formal medical definition for "child of impaired parents." However, it generally refers to a child who has at least one parent with physical, mental, or psychological challenges that impact their ability to care for themselves and/or their children. These impairments may include substance abuse disorders, mental illnesses, chronic medical conditions, or developmental disabilities.

Children of impaired parents often face unique challenges and stressors in their lives, which can affect their emotional, social, and cognitive development. They may have to take on additional responsibilities at home, experience neglect or abuse, or witness disturbing behaviors related to their parent's impairment. As a result, these children are at higher risk for developing mental health issues, behavioral problems, and academic difficulties.

Support services and interventions, such as family therapy, counseling, and community resources, can help mitigate the negative effects of growing up with impaired parents and improve outcomes for these children.

Osmotic demyelination syndrome is the term used for both central pontine myelinolysis and extrapontine myelinolysis. Central ... In about ten per cent of people with central pontine myelinolysis, extrapontine myelinolysis is also found. In these cases ... Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the ... Central pontine' indicated the site of the lesion and 'myelinolysis' was used to emphasise that myelin was affected. The ...
"Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients". AMA Arch Neurol ... Adams also first described central pontine myelinolysis. Adams died in Boston of complications from congestive heart failure, ...
"Central pontine myelinolysis following 'slow' correction of hyponatremia". Clinical Neurology and Neurosurgery. 97 (4): 340-343 ... patients may develop central pontine myelinolysis, irrespective of whether the correction of hyponatremia is kept slow. ... India portal "CSIR". Central Council of Industrial Research. 30 June 2003. Retrieved 2 October 2014. "Controversy". Hindustan ...
Martin RJ (September 2004). "Central pontine and extrapontine myelinolysis: the osmotic demyelination syndromes". Journal of ...
Central pontine myelinolysis synd/2922 at Who Named It? E. Marchiafava, A. Bignami. Sopra un'alterazione del corpo calloso ...
McKee, A.C.; Winkelman, M.D.; Banker, B.Q. (1988). "Central pontine myelinolysis in severely burned patients: relationship to ... neonatal hypoxia and central pontine myelinolysis. In 1956, she married neurologist Maurice Victor, best known for coauthoring ... Banker, B.Q. (1964). "Spongy Degeneration of the Central Nervous System in Infancy". Neurology. 14 (11): 981-1001. doi:10.1212/ ...
Raising the serum sodium concentration too rapidly may cause central pontine myelinolysis. Avoid correction by more than 12 mEq ... Ashrafian, H.; Davey, P. (2001). "A review of the causes of central pontine myelinosis: yet another apoptotic illness?". ... The causes of SIADH are grouped into six categories: 1) central nervous system diseases that directly stimulate the ... A list of common causes is below: Central nervous system-related causes Infections Meningitis, encephalitis, brain abscess, ...
The basis pons undergoes demyelination in the condition known as central pontine myelinolysis. This condition is due to the ... The basal pontine nuclei provides the most information to the cerebellum. These pontine nuclei are integral in helping the ... An integral part of the basilar pons is the pontine nuclei. The pontine nuclei are responsible for projecting axons that go to ... Doing this makes the axons change into the transverse pontine fibers. The fibers of the pontine nuclei are all important to ...
In June 2016, a journal article was written on a central pontine myelinolysis presence. And from doing radiology scans within ... Grémain, V.; Richard, L.; Langlois, V.; Marie, I. (June 2016). "Imaging in central pontine myelonolysis: animals in the brain ...
The risk of central pontine myelinolysis does not apply assuming the hypoatraemia is acute. Generally, 100 mL of hypertonic ... Fluids containing glycine can be toxic to the cardiovascular and central nervous systems if infused in large amounts and should ... Blood pressure should be monitored via insertion of a central line and arterial line. Inotropes may be employed judiciously to ...
"Efficacy of clozapine in a non-schizophrenic patient with psychogenic polydipsia and central pontine myelinolysis". Human ... June 1999). "Urinary excretion of aquaporin-2 water channel differentiates psychogenic polydipsia from central diabetes ... weakened or absent in central DI). Some patients, most often with a history of mental illness, show a shrunken cortex and ... "Use of T1-weighted MR imaging to differentiate between primary polydipsia and central diabetes insipidus". American Journal of ...
... and central pontine myelinolysis. These result in lesions to key areas of the brain involved in planning, executing, or ... Neurological injury due to damage in the central or peripheral nervous system may result in weakness, paralysis, or a lack of ...
Central pontine myelinolysis is a demyelinating disease that causes difficulty with sense of balance, walking, sense of touch, ... The superior pontine sulcus separates the pons from the midbrain. Posteriorly, the pons curves on either side into a middle ... Most of the pons is supplied by the pontine arteries, which arise from the basilar artery. A smaller portion of the pons is ... The pons can be broadly divided into two parts: the basilar part of the pons (ventral pons), and the pontine tegmentum (dorsal ...
Other conditions such as central pontine myelinolysis have about a third of patients recover and the other two-thirds ... CNS neuropathies such as those produced by vitamin B12 deficiency Central pontine myelinolysis Myelopathies such as tabes ... Demyelinating diseases can be divided in those affecting the central nervous system (CNS) and those affecting the peripheral ... Both myelinoclastic and leukodystrophic modes of disease may result in lesional demyelinations of the central nervous system. ...
... "central pontine myelinolysis" (CPM). That disorder is characterized by major neurologic damage, often of a permanent nature. ...
... or conditions such as central pontine myelinolysis that are associated with acute acquired insult.)[citation needed] Examples ... A hereditary CNS demyelinating disease is a demyelinating central nervous system disease that is primarily due to an inherited ... "Hereditary Central Nervous System Demyelinating Diseases - Genetics Home Reference". Archived from the original on 2010-04-08. ...
... central pontine myelinolysis, edema). Special considerations with the treatment of potomania are needed. Because this could be ...
... and central pontine myelinolysis. Symptoms include malaise, weight loss, irritability and confusion. In Western countries, ... The cytosolic enzyme transketolase is central to the pentose phosphate pathway, a major route for the biosynthesis of the ...
These conditions are listed below: Central nervous system tumor Central pontine myelinolysis Cerebrovascular diseases Drug ... cerebral injury Peripheral or central trauma Toxins Secondary spasmodic torticollis is diagnosed when any of the following are ...
... myopathy Canavan disease Capgras delusion Carpal tunnel syndrome Causalgia Central pain syndrome Central pontine myelinolysis ...
... a computer simulation of cellular structures Central pontine myelinolysis, a neurological disease Certified Professional ... a Catholic order in France Central Park Media, a U.S. entertainment company Chicago Public Media, a National Public Radio ...
Rarer conditions associated with PBA include gelastic epilepsy, dacrystic epilepsy, central pontine myelinolysis, ... Arthur Fleck, the central character of the 2019 film Joker, displays signs of pseudobulbar affect, which are said to be what ...
... myelinolysis, central pontine MeSH C10.228.140.163.780 - reye syndrome MeSH C10.228.140.163.960 - wernicke encephalopathy MeSH ... central MeSH C10.228.140.068.094 - auditory perceptual disorders MeSH C10.228.140.068.432 - hearing loss, central MeSH C10.228. ... central nervous system MeSH C10.228.140.300.850.125 - aids arteritis, central nervous system MeSH C10.228.140.300.850.250 - ... central nervous system MeSH C10.500.190.600 - central nervous system venous angioma MeSH C10.500.190.800 - sinus pericranii ...
... myelinolysis, central pontine MeSH C18.452.100.780 - Reye syndrome MeSH C18.452.100.960 - Wernicke encephalopathy MeSH C18.452. ...
... anemia hyponatremia Wernicke's encephalopathy kidney failure central pontine myelinolysis coagulopathy atrophy Mallory-Weiss ... Home care is available in the form of a peripherally inserted central catheter (PICC) line for hydration and nutrition. Home ...
... greatly increases risk of central pontine myelinolysis (CPM), and so requires constant monitoring of the person's response. ... As such, concentrations greater than 3% NaCl should normally be administered via a central venous catheter, also known as a ' ... central line'. Such hypertonic saline is normally available in two strengths, the former of which is more commonly administered ... also via central line), often in conjunction with supplementary diuretics, in the treatment of traumatic brain injury. Dextrose ...
... formerly designated central pontine myelinolysis) secondary to excessively rapid correction of hyponatremia [>1 mEq/L/h]) A ...
Osmotic demyelination syndrome is the term used for both central pontine myelinolysis and extrapontine myelinolysis. Central ... In about ten per cent of people with central pontine myelinolysis, extrapontine myelinolysis is also found. In these cases ... Central pontine myelinolysis is a neurological condition involving severe damage to the myelin sheath of nerve cells in the ... Central pontine indicated the site of the lesion and myelinolysis was used to emphasise that myelin was affected. The ...
Adams et al described central pontine myelinolysis (CPM) as a unique clinical entity. They published their findings in 1958, ... Central pontine myelinolysis may complicate liver transplantation surgery. [9] Consider central pontine myelinolysis when ... encoded search term (Central Pontine Myelinolysis) and Central Pontine Myelinolysis What to Read Next on Medscape ... What is the prognosis of central pontine myelinolysis (CPM)?. What are the possible complications of central pontine ...
Central Pontine" by people in this website by year, and whether "Myelinolysis, Central Pontine" was a major or minor topic of ... "Myelinolysis, Central Pontine" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Myelinolysis, Central Pontine" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Myelinolysis, Central Pontine". ...
central-pontine-myelinolysis-4 (1). Previous. Next Publié 26 mai 2015. à 1024 × 1024 dans Atteintes des noyaux gris centraux ( ...
Danyalian A, Heller D. Central Pontine Myelinolysis. [Updated 2019 Dec 11]. In: StatPearls [Internet]. Treasure Island (FL): ...
Central Pontine Myelinolysis (National Institute of Neurological Disorders and Stroke) * Hepatic Encephalopathy (American Liver ... Central Nervous System: The Brain and Spinal Cord (Nemours Foundation) Also in Spanish ...
Central pontine myelinolysis. Kiley MA, King M, Burns RJ. Kiley MA, et al. Among authors: burns rj. J Clin Neurosci. 1999 Mar;6 ...
Classically, central pontine myelinolysis affects the central midline portion of the basis pontis. Marchiafava-Bignami disease ... Central pontine myelinolysis. Luxol fast blue (LFB) stain highlights loss of myelin in the midline region of basis pontis in ... Central pontine myelinolysis. Luxol fast blue (LFB) stain highlights loss of myelin in the midline region of basis pontis in ... Central pontine myelinolysis with gray discoloration in the midline basis pontis (arrow). View Media Gallery ...
Central pontine myelinolysis. BAILEY OT, BRUNO MS, OBER WB. BAILEY OT, et al. Am J Med. 1960 Nov;29:902-6. doi: 10.1016/0002- ...
Demyelination is a hallmark of central pontine myelinolysis (CPM). Neuropsychiatric manifestations of this condition include ... or central pontine myelinolysis? Paul Schneider1, Vicki A Nejtek2,3, Cheryl Hurd2,31Green Oaks Behavioral Health Care Services ... A case of mistaken identity: alcohol withdrawal, schizophrenia, or central pontine myelinolysis?. ... central pontine myelinolysis, hyponatremia ... PubMed Central*. 4,681. 658. 5,339. Totals. 15,449. 3,074. ...
Alcoholic Case of Central Pontine Myelinolysis with Mainly Cerebellar Signs Eur Addict Res (July,2008) ... Kuriyama A, Jackson JL, Doi A, Kamiya T: Metronidazole-induced central nervous system toxicity: a systematic review. Clin ... Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system ...
Parkinsonism and dystonia in central pontine and extrapontine myelinolysis (1 July, 1998) Free A Seiser, S Schwarz, M M ...
Central pontine myelinolysis during pregnancy: pathogenesis, diagnosis and management. J. Obstet. Gynaecol. 37, 273-279 (2017). ... Central nervous system and muscle involvement in an adolescent patient with riboflavin-responsive multiple acyl-CoA ...
Central pontine myelinolysis presenting as isolated sixth nerve palsy in third trimester of pregnancy. Gosavi T, See SJ. Ann ...
Central pontine myelinolysis (CPM), cerebral autosomal dominant arteriopathy with subcortical infarcts (CADASIL), cerebral ... Fronto-temporal dementia (FTD), fungal central nervous system (CNS) infections, such as : coccidiodal meningitis, cryptococcus ...
... central pontine and/or extrapontine myelinolysis) in 25 patients., J Neurol Neurosurg Psychiatry, 2010, , http://www.ncbi.nlm. ...
... central pontine myelinolysis (brain degeneration), seizures, confusion, malnutrition, hallucinations, peptic (stomach) ulcers, ...
Central Pontine Myelinolysis (CPM). *Medscape article. *Overcorrection of serum sodium - cannot correct too fast (more than 8- ...
Central pontine. myelinolysis (CPM). It is a demyelinating disease that makes it difficult for one to balance, walk, touch, ... severing from central pontine myelinolysis, hyponatremia should be corrected at. a speed not exceeding 10 mmol/L/24hrs. ... According to doctors, the major cause of central pontine myelinolysis is a rapid correction of low blood sodium levels which is ... the varolis bridge is subjectable to one major disease which is the central pontine myelinolysis. ...
Osmotic demyelination syndrome (previously called central pontine myelinolysis) may follow too-rapid correction of hyponatremia ... The classic pontine lesion may extend dorsally to involve sensory tracts and leave patients with a "locked-in" syndrome (an ... Rapid-onset hyponatremia is problematic because the cells of the central nervous system have not had time to remove some of the ... Symptoms mainly involve central nervous system dysfunction. However, when hyponatremia is accompanied by disturbances in total ...
Central pontine myelinolysis. *. Syphilitic myelopathy (tabes dorsalis). *. Leukoencephalopathies (i.e., progressive multifocal ... Classification of demyelinating diseases is made on the basis of whether the nerves affected are of the central nervous system ...
CENTRAL PONTINE AND EXTRAPONTINE MYELINOLYSIS IN ENCEPHALITIS Suvrendu Sankar Kar, Arijit Sinha, Bikash Chandra Seth, Biswanath ... CORRELATION BETWEEN CENTRAL CORNEAL THICK-NESS AND DIABETES IN SUDANESE PATIENTS Yasser Seddeg Abdulghani, Tahir Osman Ali ...
Central Pontine Myelinolysis Extrapontine Myelinoclasis Extrapontine Myelinolysis Myelinoclasis, Central Pontine Pontine ... Myelinolysis, Central Pontine Preferred Term Term UI T052748. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1994). ... Pontine Myelinolysis, Central Term UI T052747. Date09/09/1992. LexicalTag NON. ThesaurusID NLM (1994). ... Myelinolysis, Central Pontine Preferred Concept UI. M0026656. Scope Note. A demyelinating condition affecting the PONS and ...
Central pontine myelinolysis with clinical recovery: MR documentation. Ragland, R. L., Duffis, A. W., Gendelman, S., Som, P. M. ...
The patient with central pontine myelinolysis lived in a persistent vegetative state for 2 years. ... central pontine myelinolysis (one patient), dysartria (one patient), myopathy (one patient) and mutism (one patient). The ...
Central pontine myelinolysis associated with low potassium levels in alcoholism.. Bähr M, Sommer N, Petersen D, Wiethölter H, ...
Central pontine myelinolysis. Cortical basal ganglionic degeneration. Dystonia. Encephalitis (herpesvirus, Trypanosoma cruzi) ... Lafargue T, Brasic J. Neurodevelopmental hypothesis of schizophrenia: a central sensory disturbance. Med Hypotheses. 2000 Oct. ...
counts per minute; care plan meeting; central pontine myelinolysis; continuous passive mobilizer; continuous passive motion. ...
Central pontine myelinolysis. Same, stereotaxic biopsy. Text. Central pontine myelinolysis (another case). Osteosarcoma of ... Echinococcosis of the central nervous system. CT, MRI Same, post mortem examination. Same, scanned microscopical slides. Same, ... Central neurocytoma Same, HE, IH. Pictured: astrocytic differentiation F. 75 yr. Occipital metastasis of follicular carcinoma ...

No FAQ available that match "myelinolysis central pontine"

No images available that match "myelinolysis central pontine"