Inflammation of the spinal cord. Relatively common etiologies include infections; AUTOIMMUNE DISEASES; SPINAL CORD; and ischemia (see also SPINAL CORD VASCULAR DISEASES). Clinical features generally include weakness, sensory loss, localized pain, incontinence, and other signs of autonomic dysfunction.
A syndrome characterized by acute OPTIC NEURITIS; MYELITIS, TRANSVERSE; demyelinating and/or necrotizing lesions in the OPTIC NERVES and SPINAL CORD; and presence of specific autoantibodies to AQUAPORIN 4.
SCHISTOSOMIASIS of the brain, spinal cord, or meninges caused by infections with trematodes of the genus SCHISTOSOMA (primarily SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; and SCHISTOSOMA HAEMATOBIUM in humans). S. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. S. mansoni and S. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (From Joynt, Clinical Neurology, 1998, Ch27, pp61-2)
Aquaporin 4 is the major water-selective channel in the CENTRAL NERVOUS SYSTEM of mammals.
A PREDNISOLONE derivative with similar anti-inflammatory action.
A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.
Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
Severe or complete loss of motor function in the lower extremities and lower portions of the trunk. This condition is most often associated with SPINAL CORD DISEASES, although BRAIN DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; and MUSCULAR DISEASES may also cause bilateral leg weakness.
A diminution of the skeletal muscle tone marked by a diminished resistance to passive stretching.
Infections of the BRAIN; SPINAL CORD; or MENINGES caused by HELMINTHS (parasitic worms).
Parenchymatous NEUROSYPHILIS marked by slowly progressive degeneration of the posterior columns, posterior roots, and ganglia of the spinal cord. The condition tends to present 15 to 20 years after the initial infection and is characterized by lightening-like pains in the lower extremities, URINARY INCONTINENCE; ATAXIA; severely impaired position and vibratory sense, abnormal gait (see GAIT DISORDERS, NEUROLOGIC), OPTIC ATROPHY; Argyll-Robertson pupils, hypotonia, hyperreflexia, and trophic joint degeneration (Charcot's Joint; see ARTHROPATHY, NEUROGENIC). (From Adams et al., Principles of Neurology, 6th ed, p726)
A syndrome characterized by headache, neck stiffness, low grade fever, and CSF lymphocytic pleocytosis in the absence of an acute bacterial pathogen. Viral meningitis is the most frequent cause although MYCOPLASMA INFECTIONS; RICKETTSIA INFECTIONS; diagnostic or therapeutic procedures; NEOPLASTIC PROCESSES; septic perimeningeal foci; and other conditions may result in this syndrome. (From Adams et al., Principles of Neurology, 6th ed, p745)
Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.

Influence of sex on clinical features, laboratory findings, and complications of typhoid fever. (1/166)

Clinical features, laboratory findings, and complications of typhoid fever were correlated with sex through a retrospective case note review of 102 hospitalized culture-positive patients in Durban, South Africa. Intestinal perforation (P = 0.04), occult blood losses in stools (P = 0.04), and a mild reticulocytosis in the absence of hemolysis (P = 0.02) occurred more frequently in males than in females. A single pretreatment Widal O antibody titer > or = 1:640 was also a statistically significant occurrence in males (P = 0. 006). Female patients were significantly more severely ill (P = 0.0004) on admission and had chest signs consistent with bronchopneumonia (P = 0.04), transverse myelitis (P = 0.04), abnormal liver function test results (P = 0.0003), and abnormal findings in urinalyses (P = 0.02). Typhoid hepatitis (P = 0.04) and glomerulonephritis (P = 0.02) were present significantly more frequently in females. Whether these differences were due to differences in host's immune response to acute infection need to be determined in a prospective study.  (+info)

Unusual cervical spinal cord toxicity associated with intra-arterial carboplatin, intra-arterial or intravenous etoposide phosphate, and intravenous cyclophosphamide in conjunction with osmotic blood brain-barrier disruption in the vertebral artery. (2/166)

BACKGROUND AND PURPOSE: When the clinical and radiologic characteristics of an unusual cervical spinal cord complication of intra-arterial (IA) chemotherapy with blood brain-barrier (BBB) disruption in the vertebral circulation are documented. Seven cases are reported and analyzed in search of a pathophysiologic explanation. METHODS: We retrospectively identified 94 patients who received a total of 380 standardized regimens of IA carboplatin, IA or IV etoposide phosphate, and IV cyclophosphamide infusion in conjunction with osmotic BBB disruption of the vertebral artery. We describe seven of those patients in whom unexpected neck pain developed followed by neurologic symptoms primarily in the upper extremities. RESULTS: The symptoms correlated with MR abnormalities (T1 hypointensity, T2 hyperintensity, and unusual contrast enhancement) in the cervical spinal cord, usually involving the gray matter. The neurologic deficits and MR changes were generally transient. One patient who received a flu vaccination 48 hours before the chemotherapy incurred progressive myelitis and expired. CONCLUSION: The pathophysiology of this complication is probably multifactorial but may be related to vascular streaming and an atypical inflammatory toxic reaction to carboplatin and etoposide. The complication has not recurred during a 6-month period following modification of the protocol.  (+info)

Acute myelitis after asthma attacks with onset after puberty. (3/166)

A poliomyelitis-like illness after asthma attacks has been found and is called asthmatic amyotrophy (Hopkins' syndrome). All of the previously reported cases were under 13 years of age. Three patients are described who developed acute myelitis after asthma attacks at 15, 22, and 73 years of age. All of them showed acute flaccid monoparesis, and needle EMG disclosed denervation potentials in the relevant muscles. In addition, in the two adult patients the sensory or pyramidal tracts were involved, and evoked potential studies confirmed an involvement of the pyramidal tracts in one of them. This 22 year old patient showed a second episode of monoparesis in the other limb after another asthma attack. All three patients had no significant changes in their antiviral antibody titres, whereas every patient had hyperIgEaemia and allergen specific IgE. These findings suggest that asthmatic amyotrophy can develop after puberty and that patients who develop this disease in adulthood seem to show both a widespread involvement of the spinal cord and a more varied course.  (+info)

Tuberculous radiculomyelitis complicating tuberculous meningitis: case report and review. (4/166)

Tuberculous radiculomyelitis (TBRM) is a complication of tuberculous meningitis (TBM), which has been reported rarely in the modern medical literature. We describe a case of TBRM that developed in an human immunodeficiency virus (HIV)-infected patient, despite prompt antituberculous treatment. To our knowledge, this is the second case of TBRM reported in an HIV-infected patient. We also review 74 previously reported cases of TBRM. TBRM develops at various periods after TBM, even in adequately treated patients after sterilization of the cerebrospinal fluid (CSF). The most common symptoms are subacute paraparesis, radicular pain, bladder disturbance, and subsequent paralysis. CSF evaluation usually shows an active inflammatory response with a very high protein level. MRI and CT scan are critical for diagnosis, revealing loculation and obliteration of the subarachnoid space along with linear intradural enhancement. As in other forms of paradoxical reactions to antituberculous treatment, there is evidence that steroid treatment might have a beneficial effect.  (+info)

Nationwide survey of the annual prevalence of viral and other neurological infections in Japanese inpatients. (5/166)

OBJECTIVE: To estimate the annual prevalence of viral and other neurological infections at large hospitals in Japan during the period from 1989 to 1991. METHODS: A nationwide questionnaire survey on the numbers of inpatients with viral and other neurological infections was sent for completion to the chiefs of Departments of Internal Medicine, Neurology and Pediatrics at all hospitals with more than 200 beds. RESULTS: The average annual number of inpatients (and the number per 10(6) population) with encephalitis in large hospitals was estimated to be 2,200+/-400 (17.7+/-3.2), while it was 32,000+/-16,000 (258+/-129) for meningitis, and 650+/-50 (5.2+/-0.4) for myelitis. Among the inpatients with encephalitis, meningitis, and myelitis, an unknown etiology was the most common (51.2% in encephalitis, 73.2% in meningitis, and 36.3% in myelitis), followed by a viral etiology for all three diseases. CONCLUSION: The first estimate was made of the annual prevalence of viral and other neurological infections and their etiology in Japan.  (+info)

Toxoplasma gondii myelitis in a patient with adult T-cell leukemia-lymphoma. (6/166)

Adult T cell leukemia-lymphoma (ATL) caused by HTLV-I may be associated with severe immunosupression and several opportunistic infections. Toxoplasmic encephalitis is a common central nervous system opportunistic infection in severely immunosupressed patients, however spinal cord involvement by this parasite is rare. In this paper, we report a case of toxoplasmic myelitis in a patient with ATL.  (+info)

An immunological syndrome featuring transverse myelitis, Evans syndrome and pulmonary infiltrates after unrelated bone marrow transplant in a patient with severe aplastic anemia. (7/166)

A patient with severe aplastic anemia underwent a matched unrelated bone marrow transplant, following which he developed a complex autoimmune syndrome. This featured transverse myelitis, immune mediated Coombs positive hemolytic anemia and immune thrombocytopenia (Evans syndrome), pulmonary infiltrates, eosinophilia, muscle pains and cramps and lichenoid dermatitis all of which may represent manifestations of graft-versus-host disease as they showed response to immunosuppression. Thus, although immune-mediated cytopenias after an allogeneic bone marrow transplant are rare, they should be considered as a possible cause of cytopenia in post-transplant patients.  (+info)

Acute flaccid paralysis in infants and young children with enterovirus 71 infection: MR imaging findings and clinical correlates. (8/166)

BACKGROUND AND PURPOSE: Enterovirus 71 (EV71) infection is now considered an important cause of childhood acute flaccid paralysis. The purpose of our study was to determine whether EV71-infection-related acute flaccid paralysis in infants and young children has characteristic MR imaging patterns. METHODS: Seven infants and young children with acute paralysis of the upper or lower extremities and positive EV71 cultures underwent spinal MR studies during an outbreak of hand-foot-and-mouth disease in Taiwan in 1998. RESULTS: Acute paralysis was observed in one upper extremity in two patients, in one lower extremity in three patients, and in both lower extremities in two patients. None of the patients had sensory impairment or bulbar palsy. MR studies showed unilateral or bilateral hyperintense lesions in the anterior horn regions of the cord on T2-weighted images in six patients. No abnormal signal was present in one patient. Two of three patients who received intravenous injections of contrast material had ventral root enhancement on T1-weighted images. One of them also had enhancement of the unilateral anterior horn cells. At clinical follow-up, both patients with bilateral anterior horn abnormalities had residual motor weakness, whereas only one of the five patients with unilateral involvement had residual weakness. CONCLUSION: EV71 radiculomyelitis tends to be unilateral and to specifically involve both the anterior horn cells of the cord and the ventral roots. MR imaging allows early detection of spinal cord and root lesions.  (+info)

Myelitis is a medical term that refers to inflammation of the spinal cord. This inflammation can cause damage to the myelin sheath, which is the protective covering of nerve fibers in the spinal cord. As a result, the transmission of nerve impulses along the spinal cord may be disrupted, leading to various neurological symptoms.

Myelitis can affect any part of the spinal cord and can have many different causes, including infections (such as viral or bacterial infections), autoimmune disorders (such as multiple sclerosis), and other conditions (such as spinal cord injuries or tumors). The specific symptoms of myelitis depend on the location and severity of the inflammation. They may include muscle weakness, numbness or tingling sensations, pain, bladder or bowel dysfunction, and difficulty with coordination and balance.

Myelitis can be a serious condition that requires prompt medical attention and treatment. Treatment typically focuses on addressing the underlying cause of the inflammation, as well as managing symptoms and supporting recovery.

Neuromyelitis optica (NMO), also known as Devic's disease, is an autoimmune disorder that affects the central nervous system (CNS). It primarily causes inflammation and damage to the optic nerves (which transmit visual signals from the eye to the brain) and the spinal cord. This results in optic neuritis (inflammation of the optic nerve, causing vision loss) and myelitis (inflammation of the spinal cord, leading to motor, sensory, and autonomic dysfunction).

A key feature of NMO is the presence of autoantibodies against aquaporin-4 (AQP4-IgG), a water channel protein found in astrocytes (a type of glial cell) in the CNS. These antibodies play a crucial role in the development of the disease, as they target and damage the AQP4 proteins, leading to inflammation, demyelination (loss of the protective myelin sheath around nerve fibers), and subsequent neurological dysfunction.

NMO is distinct from multiple sclerosis (MS), another autoimmune disorder affecting the CNS, as it has different clinical features, radiological findings, and treatment responses. However, NMO can sometimes be misdiagnosed as MS due to overlapping symptoms in some cases. Accurate diagnosis of NMO is essential for appropriate management and treatment, which often includes immunosuppressive therapies to control the autoimmune response and prevent further damage to the nervous system.

Neuroschistosomiasis is a form of schistosomiasis, which is a parasitic infection caused by Schistosoma species. It is characterized by the invasion and inflammation of the central nervous system (CNS) by the parasite's eggs or larvae. This can lead to various neurological symptoms such as seizures, headaches, visual disturbances, and motor or sensory deficits. Neuroschistosomiasis is a serious and potentially life-threatening condition that requires prompt diagnosis and treatment.

The two Schistosoma species most commonly associated with neuroschistosomiasis are S. japonicum and S. mansoni. The parasites typically enter the human body through skin contact with contaminated water, where they mature into adult worms in the bloodstream. Female worms then lay eggs, some of which may be carried to the CNS by the circulatory system.

Neuroschistosomiasis can occur in both acute and chronic forms. Acute neuroschistosomiasis is characterized by an inflammatory response to the parasite's eggs or larvae, which can cause eosinophilic meningitis or encephalitis. Chronic neuroschistosomiasis may result in the formation of granulomas around the eggs, leading to various neurological symptoms depending on the location and extent of the damage.

Diagnosis of neuroschistosomiasis typically involves a combination of clinical evaluation, imaging studies (such as MRI or CT scans), and laboratory tests (such as serology or CSF analysis). Treatment usually consists of anti-parasitic drugs such as praziquantel, combined with corticosteroids to manage the inflammatory response. In severe cases, surgical intervention may be necessary to alleviate symptoms or prevent further damage.

Aquaporin 4 (AQP4) is a water channel protein that is primarily found in the membranes of astrocytes, which are a type of glial cell in the central nervous system. AQP4 plays a crucial role in the regulation of water homeostasis and the clearance of excess fluid from the brain and spinal cord. It also facilitates the rapid movement of water across the blood-brain barrier and between astrocytes, which is important for maintaining proper neuronal function and protecting the brain from edema or swelling.

Mutations in the AQP4 gene can lead to various neurological disorders, such as neurodegenerative diseases and neuromyelitis optica spectrum disorder (NMOSD), a severe autoimmune condition that affects the optic nerves and spinal cord. In NMOSD, the immune system mistakenly attacks AQP4 proteins, causing inflammation, demyelination, and damage to the nervous tissue.

Methylprednisolone is a synthetic glucocorticoid drug, which is a class of hormones that naturally occur in the body and are produced by the adrenal gland. It is often used to treat various medical conditions such as inflammation, allergies, and autoimmune disorders. Methylprednisolone works by reducing the activity of the immune system, which helps to reduce symptoms such as swelling, pain, and redness.

Methylprednisolone is available in several forms, including tablets, oral suspension, and injectable solutions. It may be used for short-term or long-term treatment, depending on the condition being treated. Common side effects of methylprednisolone include increased appetite, weight gain, insomnia, mood changes, and increased susceptibility to infections. Long-term use of methylprednisolone can lead to more serious side effects such as osteoporosis, cataracts, and adrenal suppression.

It is important to note that methylprednisolone should be used under the close supervision of a healthcare provider, as it can cause serious side effects if not used properly. The dosage and duration of treatment will depend on various factors such as the patient's age, weight, medical history, and the condition being treated.

The spinal cord is a major part of the nervous system, extending from the brainstem and continuing down to the lower back. It is a slender, tubular bundle of nerve fibers (axons) and support cells (glial cells) that carries signals between the brain and the rest of the body. The spinal cord primarily serves as a conduit for motor information, which travels from the brain to the muscles, and sensory information, which travels from the body to the brain. It also contains neurons that can independently process and respond to information within the spinal cord without direct input from the brain.

The spinal cord is protected by the bony vertebral column (spine) and is divided into 31 segments: 8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal. Each segment corresponds to a specific region of the body and gives rise to pairs of spinal nerves that exit through the intervertebral foramina at each level.

The spinal cord is responsible for several vital functions, including:

1. Reflexes: Simple reflex actions, such as the withdrawal reflex when touching a hot surface, are mediated by the spinal cord without involving the brain.
2. Muscle control: The spinal cord carries motor signals from the brain to the muscles, enabling voluntary movement and muscle tone regulation.
3. Sensory perception: The spinal cord transmits sensory information, such as touch, temperature, pain, and vibration, from the body to the brain for processing and awareness.
4. Autonomic functions: The sympathetic and parasympathetic divisions of the autonomic nervous system originate in the thoracolumbar and sacral regions of the spinal cord, respectively, controlling involuntary physiological responses like heart rate, blood pressure, digestion, and respiration.

Damage to the spinal cord can result in various degrees of paralysis or loss of sensation below the level of injury, depending on the severity and location of the damage.

Medical Definition:

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic imaging technique that uses a strong magnetic field and radio waves to create detailed cross-sectional or three-dimensional images of the internal structures of the body. The patient lies within a large, cylindrical magnet, and the scanner detects changes in the direction of the magnetic field caused by protons in the body. These changes are then converted into detailed images that help medical professionals to diagnose and monitor various medical conditions, such as tumors, injuries, or diseases affecting the brain, spinal cord, heart, blood vessels, joints, and other internal organs. MRI does not use radiation like computed tomography (CT) scans.

Paraplegia is a medical condition characterized by partial or complete loss of motor function and sensation in the lower extremities, typically affecting both legs. This results from damage to the spinal cord, often due to trauma such as accidents, falls, or gunshot wounds, or from diseases like spina bifida, polio, or tumors. The specific area and extent of the injury on the spinal cord determine the severity and location of paralysis. Individuals with paraplegia may require assistive devices for mobility, such as wheelchairs, and may face various health challenges, including pressure sores, urinary tract infections, and chronic pain.

Muscle hypotonia, also known as decreased muscle tone, refers to a condition where the muscles appear to be flaccid or lacking in tension and stiffness. This results in reduced resistance to passive movements, making the limbs feel "floppy" or "like a rag doll." It can affect any muscle group in the body and can be caused by various medical conditions, including neurological disorders, genetic diseases, and injuries to the nervous system. Hypotonia should not be confused with muscle weakness, which refers to the inability to generate normal muscle strength.

Central nervous system helminthiasis is a medical condition that refers to the invasion and infection of the central nervous system (CNS), specifically the brain and spinal cord, by parasitic worms, also known as helminths. This rare but serious condition can occur when helminth larvae or eggs accidentally migrate from their usual location in the body to the CNS through the bloodstream or cerebrospinal fluid.

The most common types of helminths that can cause CNS helminthiasis include:

1. Neurocysticercosis: This is caused by the larval stage of the tapeworm Taenia solium, which typically infects the muscles and brain. However, when the larvae invade the CNS, they can form cysts that cause inflammation, swelling, and damage to brain tissue.
2. Echinococcosis: This is caused by the larval stage of the tapeworm Echinococcus granulosus or Echinococcus multilocularis. The larvae can form hydatid cysts in various organs, including the brain, leading to neurological symptoms.
3. Gnathostomiasis: This is caused by the larval stage of the nematode Gnathostoma spinigerum or Gnathostoma hispidum. The larvae can migrate to various organs, including the CNS, causing inflammation and damage to brain tissue.
4. Angiostrongyliasis: This is caused by the nematode Angiostrongylus cantonensis, which typically infects rats but can accidentally infect humans through contaminated food or water. The larvae can migrate to the CNS and cause eosinophilic meningitis, an inflammation of the membranes surrounding the brain and spinal cord.

Symptoms of CNS helminthiasis depend on the type of parasite involved, the location and extent of the infection, and the host's immune response. They can range from mild to severe and may include headache, seizures, weakness, numbness, vision changes, confusion, and cognitive impairment. Diagnosis is usually based on clinical presentation, imaging studies, and laboratory tests, such as serology or CSF analysis. Treatment depends on the type of parasite involved and may include antiparasitic drugs, corticosteroids, and supportive care. Prevention measures include avoiding contaminated food and water, practicing good hygiene, and using insect repellents to prevent mosquito-borne infections.

Tabes dorsalis is a late-stage complication of untreated neurosyphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It is characterized by degeneration of the posterior columns and dorsal roots of the spinal cord, leading to various neurological symptoms.

The medical definition of Tabes Dorsalis is:

A chronic progressive degenerative disease of the spinal cord, specifically affecting the dorsal root ganglia and posterior columns, caused by the tertiary stage of syphilis. The condition is characterized by a combination of motor, sensory, and autonomic disturbances, including ataxia, Romberg's sign, lightning pains, hypo- or areflexia, impaired proprioception, dissociated sensations, and Argyll Robertson pupils. If left untreated, Tabes Dorsalis can lead to significant disability and even death.

Aseptic meningitis is a type of meningitis (inflammation of the membranes covering the brain and spinal cord) that is not caused by bacterial infection. Instead, it can be due to viral infections, fungal infections, or non-infectious causes such as certain medications, chemical irritants, or underlying medical conditions. In aseptic meningitis, the cerebrospinal fluid (CSF) analysis may show increased white blood cells, typically lymphocytes, but no bacterial growth on culture. Common viral causes include enteroviruses, herpes simplex virus, and varicella-zoster virus. Treatment depends on the underlying cause and may include supportive care, antiviral medications, or immunosuppressive therapy in some cases.

Demyelinating autoimmune diseases of the central nervous system (CNS) are a group of disorders characterized by inflammation and damage to the myelin sheath, which is the protective covering that surrounds nerve fibers in the brain and spinal cord. This damage can result in various neurological symptoms, including muscle weakness, sensory loss, vision problems, and cognitive impairment.

The most common demyelinating autoimmune disease of the CNS is multiple sclerosis (MS), which affects approximately 2.3 million people worldwide. Other examples include neuromyelitis optica spectrum disorder (NMOSD), acute disseminated encephalomyelitis (ADEM), and transverse myelitis.

These conditions are thought to arise when the immune system mistakenly attacks the myelin sheath, leading to inflammation, damage, and scarring (sclerosis) in the CNS. The exact cause of this autoimmune response is not fully understood, but it is believed to involve a complex interplay between genetic, environmental, and immunological factors.

Treatment for demyelinating autoimmune diseases of the CNS typically involves a combination of medications to manage symptoms, reduce inflammation, and modify the course of the disease. These may include corticosteroids, immunosuppressive drugs, and disease-modifying therapies (DMTs) that target specific components of the immune system.

Viral myelitis Most viral myelitis is acute, but the retroviruses (such as HIV and HTLV) can cause chronic myelitis. ... Myelitis lesions usually occur in a narrow region but can be spread and affect many areas. Acute flaccid myelitis: a polio-like ... Myelitis is a rare manifestation of bacterial infection. Fungal myelitis Fungi have been reported to cause spinal cord disease ... Immunosuppressants/Immunomodulatory agents Myelitis with no definite cause seldom recurs, but for others, myelitis may be a ...
... is a disorder of the myelin sheath, which is a primary actor in the central nervous system. It has been ...
... the terms partial transverse myelitis and partial myelitis are sometimes used to specify inflammation that affects only part of ... In an article in The Lancet, Ford suggested that acute myelitis could be a post-infection syndrome in most cases (i.e. a result ... Transverse myelitis (TM) is a rare neurological condition wherein the spinal cord is inflamed. The adjective transverse implies ... Sometimes the term Transverse myelitis spectrum disorder is used. In 60% of patients the cause is idiopathic. In rare cases, it ...
"An Update on Outbreak of Paralysis in US: Acute Flaccid Myelitis". The transverse myelitis association. 2014-10-16. Archived ... Acute flaccid myelitis (AFM) is a serious condition of the spinal cord. Symptoms include rapid onset of arm or leg weakness and ... "Acute Flaccid Myelitis" (PDF). www.dhs.wisconsin.gov. January 2017. Archived (PDF) from the original on 1 May 2018. Retrieved ... "Acute Flaccid Myelitis". Centers for Disease Control and Prevention (CDC). 1 March 2019. Archived from the original on 29 March ...
He contracted transverse myelitis. in 2018, he is studying Sports Studies degree at the University of the Sunshine Coast. He ...
with James McIntosh: Turnbull, H. M.; McIntosh, J. (1926). "Encephalo-myelitis following vaccination". British Journal of ...
His findings led to a new clinical entity called Parainfectious conus myelitis, thus drawing an explanation for the unexplained ... Classification of acute transverse myelitis. The Government of India, in 2014, honoured Dr. Sunil Pradhan, by awarding him the ... Kalita, J; Shah, S; Kapoor, R; Misra, UK (1 August 2002). "Bladder dysfunction in acute transverse myelitis: magnetic resonance ... "Lower motor neuron paralysis with extensive cord atrophy in parainfectious acute transverse myelitis". Annals of Indian Academy ...
Irani DN (August 2008). "Aseptic meningitis and viral myelitis". Neurologic Clinics. 26 (3): 635-55, vii-viii. doi:10.1016/j. ...
Rooney, J. R.; Prickett, M. E.; Delaney, F. M.; Crowe, M. W. (1970-07-01). "Focal myelitis-encephalitis in horses". The Cornell ...
Martin, J. P. (May 1933). "Acute Benign Myelitis (Encephalo-myelitis)". Proc R Soc Med. 26 (7): 843-844. doi:10.1177/ ...
Optic neuritis Transverse myelitis Victoria Arlen Dale RC (April 2003). "Acute disseminated encephalomyelitis". Seminars in ... Karaali-Savrun F, Altintaş A, Saip S, Siva A (November 2001). "Hepatitis B vaccine related-myelitis?". European Journal of ...
He was born with myelitis. "Ju-Seung Lee". 2014 Winter Paralympics. Retrieved 2019-11-23. "PyeongChang 2018 Paralympic Games - ...
Mealy, Maureen (January 2011). "The Johns Hopkins Transverse Myelitis Center: One Decade of Work and the Challenges for the ... Update on transverse myelitis". Current Neurology and Neuroscience Reports. 6 (3): 236-243. doi:10.1007/s11910-006-0011-1. PMID ... as well as the director of the Johns Hopkins Transverse Myelitis Center. His area of expertise is immunopathology and the ...
Blumm, K. C. (December 18, 2013). "Kristen Johnston Diagnosed with Lupus Myelitis". People. Retrieved 2013-12-27. Schager, Nick ...
Myelitis also occurs with or without encephalitis. Sequelae persist for a year or more in approximately one third of people who ... Myelitis and spinal paralysis also occurs. In about one third of cases sequelae, predominantly cognitive dysfunction, persist ... encephalitis or myelitis. The risk of infection was noted to be increasing with age, especially in people older than 40 years ...
"Acute Flaccid Myelitis Task Force Biographies , Board of Scientific Counselors , CDC". www.cdc.gov. 2019-10-10. Retrieved 2020- ... Erbelding serves on the acute flaccid myelitis task force at the Centers for Disease Control and Prevention. Erbelding, Emily J ...
When inflammatory, it is known as myelitis. Disease that is vascular in nature is known as vascular myelopathy. In Asian ...
Young died from myelitis on 6 October 1915. St Finbarr's Cork Senior Hurling Championship (3): 1899, 1904, 1906 Cork All- ...
Warszawskie Czasopismo Lekarskie 4, 193 (1926) Przypadek myelitis. Polska Gazeta Lekarska 50, 955 (1926) Przypadek tętniaka ...
"Early-onset acute partial transverse myelitis: Case report". Journal of Dr. Behcet Uz Children's Hospital. 3 (2): 133-137. doi: ...
Beiträge zur Kenntnis der osteo myelitis, Vienna, 1896. Die pathologischen Beckenformen, Leipzig, 1904 (with Carl Breus 1852- ...
It is suspected of causing a polio-like disorder called acute flaccid myelitis (AFM). EV-D68 is one of the more than one ... The virus is one cause of acute flaccid myelitis, a rare muscle weakness, usually due to polio. In 2014, the cases of two ... "Notes from the Field: Six Cases of Acute Flaccid Myelitis in Children - Minnesota, 2018". CDC. CDC. 19 April 2019. Retrieved 25 ... "What is the relationship between EVD68 and acute flaccid myelitis?". YouTube. SRNA. 6 November 2018. (CS1 maint: location, CS1 ...
Recovery from transverse myelitis usually begins between weeks 2 and 12 following onset and may continue for up to 2 years in ... Solmaz Asnafi et al., The Frequency of Longitudinally Extensive Transverse Myelitis in MS; A Population-Based Study, October 30 ... Though it was considered for many years that traverse myelitis was a normal consequence of MS, since the discovery of anti-AQP4 ... some patients and as many as 80% of individuals with transverse myelitis are left with lasting disabilities.[citation needed] ...
Longitudinally extensive myelitis or optic neuritis associated with systemic autoimmune disease. Optic neuritis or myelitis ... Longitudinal myelitis was evident on MRI in 76[percent]. It has also been noted that percentage of children with anti-mog ... Limited forms of Devic's disease, such as single or recurrent events of longitudinally extensive myelitis, and bilateral ... Optic neuritis (monophasic and recurrent) and Transverse myelitis (monophasic and recurrent) LHON associated MS (LHON-MS), a ...
Acute flaccid myelitis (AFM) is a serious condition of the spinal cord with symptoms including rapid onset of arm or leg ... "Antibodies to Enteroviruses in Cerebrospinal Fluid of Patients with Acute Flaccid Myelitis". mBio. 10 (4): e01903-19. doi: ... "Pan-viral serology implicates enteroviruses in acute flaccid myelitis". Nature Medicine. 25 (11): 1748-1752. doi:10.1038/s41591 ...
Zugleich ein Beitrag zur Kenntnis der Myelitis acuta, Diss. Stockholm 1905 (German) Beiträge zur Kenntnis der Heine-Medinschen ...
119 Infection can produce myelitis and encephalitis: 7 Herpes simplex virus type 2 (HSV-2) Infection can produce myelitis and ... 26(617). Irani, D (2008). "Aseptic Meningitis and Viral Myelitis", Neurologic Clinics, 26(635). Davies NW, Brown LJ, Irish D, ... and myelitis Is considered the leading viral candidate for causing multiple sclerosis Human herpesvirus type 6 (HHV-6) and ... myelitis, cerebellar ataxia, Reye's syndrome, cranial neuropatheis, and postinfectious disseminated encephalomyelitis Epstein- ...
Transverse Myelitis Consortium Working Group (A Martinez-Arizala, G Barnes, S Benjamin, J Bowen, N Cutter, B de Lateur, D ... Proposed Diagnostic Criteria for Acute Transverse Myelitis, Neurology. 59, 499-505. Wegener ST, Haythornthwaite JA (2001) ...
... myelitis). Episodes of ON and myelitis can be simultaneous or successive. A relapsing disease course is common, especially in ... myelitis). Myelitis causes spinal cord dysfunction, which can result in muscle weakness, paralysis in the limbs, lost or ... Related Myelitis: Characterization and Comparison with Aquaporin-4-IgG Myelitis, Elia Sechi, P. Pearse Morris, Andrew McKeon, ... The myelitis can be transverse, affecting an entire cross-section of the spinal cord, and showing bilateral symptoms. The ...
Around this time, she began to develop symptoms of myelitis. In Porto, Sister Mary reported several messages from Jesus Christ ...
Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. When the spinal cord gets inflamed, ... How is transverse myelitis diagnosed and treated? Diagnosing transverse myelitis. Physicians diagnose transverse myelitis by ... What is transverse myelitis?. Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. When ... Who is more likely to get transverse myelitis?. Transverse myelitis can affect people of any age, gender, or race. It does not ...
About Acute Flaccid Myelitis. AFM is an uncommon but serious neurologic condition that causes muscle weakness, sometimes ...
Viral myelitis Most viral myelitis is acute, but the retroviruses (such as HIV and HTLV) can cause chronic myelitis. ... Myelitis lesions usually occur in a narrow region but can be spread and affect many areas. Acute flaccid myelitis: a polio-like ... Myelitis is a rare manifestation of bacterial infection. Fungal myelitis Fungi have been reported to cause spinal cord disease ... Immunosuppressants/Immunomodulatory agents Myelitis with no definite cause seldom recurs, but for others, myelitis may be a ...
Acute flaccid myelitis (AFM) is a rare but serious neurologic disease. It can cause sudden arm or leg weakness and a loss of ... Acute flaccid myelitis (Medical Encyclopedia) Also in Spanish * Acute Flaccid Myelitis (AFM) (Centers for Disease Control and ... Acute Flaccid Myelitis (AFM) (For Parents) (Nemours Foundation) Also in Spanish * CDC Vital Signs: Acute Flaccid Myelitis (AFM) ... What is acute flaccid myelitis (AFM)?. Acute flaccid myelitis (AFM) is a neurologic disease. It is rare, but serious. It ...
Acute Flaccid Myelitis in the United States-August - December 2014: Results of Nation-Wide Surveillance ... Her areas of expertise include measles, mumps, rubella, polio, cytomegalovirus, and acute flaccid myelitis. Her previous work ... Notes from the Field: Acute Flaccid Myelitis Among Persons Aged ?21 Years- United States, August 1-November 13, 2014 ... Notice to Clinicians: Continued Vigilance Urged for Cases of Acute Flaccid Myelitis, COCA Clinical Reminder ...
The terms Myelitis, Transverse Myelitis and Acute Transverse Myelitis are used interchangeably ... Myelitis is typically bilateral but may be unilateral in early or atypical cases (partial Transverse Myelitis) ... Myelitis may be unilateral or bilateral, and may effect only some long tracts but not others. *May affect both ascending ( ... Myelitis typically affects a full triad of sensory, motor and Autonomic Dysfunction once disease has progressed. *However, at ...
... is a medical condition characterized by muscular weakness and myelitis, which is the medical term used to describe inflammation ... Acute flaccid myelitis (AFM) is a medical condition characterized by muscular weakness and myelitis, which is the medical term ... What Causes Acute flaccid Myelitis?. Although no definite cause of AFM has been found to date, certain viruses have been ... AFM is classified as a sub-type or variant of transverse myelitis, which clinically presents with symptoms and signs that are ...
Acute flaccid myelitis (AFM) presents significant challenges not only to patients but also to researchers, and efforts must be ... Acute flaccid myelitis requires galvanized research response. NIH experts review puzzling muscle paralysis condition in ... DM Morens et al. Acute Flaccid Myelitis: Something Old and Something New. mBio DOI: 10.1128/mBio.00521-19 (2019). ...
Transverse myelitis (TM) is a rare neurological condition caused by inflammation of your spinal cord. It often causes sudden ... Who does transverse myelitis affect?. Transverse myelitis (TM) can occur in any person at any age. But it seems to affect ... How is transverse myelitis (TM) treated?. The goals of treatment for transverse myelitis (TM) include:. *Treating the cause of ... What is transverse myelitis (TM)?. Transverse myelitis (TM) is a rare neurological condition caused by inflammation of your ...
CanadaHelps 2023. CanadaHelps is a registered charity , Charity Registration Number: 896568417RR0001 ...
Diffuse myelitis in a 9-month-old infant: case report and review of the literature  ...
... acute flaccid myelitis - Sharing our stories on preparing for and responding to public health events ...
Acute Flaccid Myelitis (AFM). What Is Acute Flaccid Myelitis?. Acute flaccid myelitis (AFM) is a rare condition that affects ... What Are the Signs & Symptoms of Acute Flaccid Myelitis?. Acute flaccid myelitis (mye-uh-LYE-tiss) often happens after a ... What Causes Acute Flaccid Myelitis?. Experts think that AFM is caused by certain types of viruses, such as enterovirus D68. ... For more information about acute flaccid myelitis, visit the CDCs AFM page. ...
Acute flaccid myelitis (AFM) presents significant challenges not only to patients but also to researchers, and efforts must be ... Acute flaccid myelitis (AFM) presents significant challenges not only to patients but also to researchers, and efforts must be ... Acute Flaccid Myelitis Requires Galvanized Research Response. NIH Experts Review Puzzling Muscle Paralysis Condition in ... Acute flaccid myelitis: Something old and something new. mBio DOI: 10.1128/mBio.00521-19 (2019). ...
Acute flaccid myelitis (AFM) is an incompletely understood neurologic disorder occurring in epidemic fashion causing weakness ... Acute Flaccid Myelitis William Ide 1 , Michelle Melicosta 2 , Melissa K Trovato 3 ... Acute Flaccid Myelitis William Ide et al. Phys Med Rehabil Clin N Am. 2021 Aug. ... Acute Flaccid Myelitis Associated With Enterovirus D68: A Review. Christy A, Messacar K. Christy A, et al. J Child Neurol. 2019 ...
... transverse myelitis occurs due to an issue that is causing inflammation in the spinal cord. ... What causes transverse myelitis?. In most cases, transverse myelitis occurs due to an issue that is causing inflammation in the ... keyboard_arrow_left Back to Transverse Myelitis Clinic At Northwestern Memorial Hospital ...
Notice of Interest in Advancing Research in Acute Flaccid Myelitis and Guillain-Barre Syndrome NOT-NS-19-029. NINDS ... Notice of Interest in Advancing Research in Acute Flaccid Myelitis and Guillain-Barre Syndrome Notice Number: NOT-NS-19-029 ... A recent increase in cases of a polio-like illness in children called Acute Flaccid Myelitis (AFM) has drawn attention to gaps ...
Find out about resources for coalitions and get updated information about acute flaccid myelitis. ... Acute flaccid myelitis. The CDCs July 2019 Vital Signs report included a summary of recent experience with acute flaccid ... Vaccine Resources: Tools for Coalitions and Info about Acute Flaccid Myelitis. Published on Jul 25, 2019 ... myelitis (AFM). Given that most cases in recent outbreaks have occurred in late summer and early fall, the publication offers ...
Acute (transverse) myelitis. *There are 3 ICD-9-CM codes below 341.2 that define this diagnosis in greater detail. Do not use ... acute (transverse) myelitis (in) (due to):*following immunization procedures (323.52. )*infection classified elsewhere (323.42 ...
acute transverse myelitis NOS (341.20. )*acute transverse myelitis in conditions classified elsewhere (341.21. )*bacterial:* ... Encephalitis myelitis and encephalomyelitis. *There are 9 ICD-9-CM codes below 323 that define this diagnosis in greater detail ...
Learn about diagnosis and specialist referrals for Acute flaccid myelitis. ...
Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. When the spinal cord gets inflamed, ... How is transverse myelitis diagnosed and treated? Diagnosing transverse myelitis. Physicians diagnose transverse myelitis by ... What is transverse myelitis?. Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. When ... Who is more likely to get transverse myelitis?. Transverse myelitis can affect people of any age, gender, or race. It does not ...
Panageas, A. (2019). Acute Flaccid Myelitis: A Dangerous Polio-like Illness. D.U.Quark, 3 (2). Retrieved from https://dsc.duq. ...
Acute Transverse Myelitis - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical ... Symptoms and Signs of Acute Transverse Myelitis Symptoms of acute transverse myelitis may include pain in the neck, back, or ... Acute transverse myelitis is most commonly due to multiple sclerosis Multiple Sclerosis (MS) Multiple sclerosis (MS) is ... Transverse myelitis occurs with optic neuritis in neuromyelitis optica Neuromyelitis Optica Spectrum Disorder (NMOSD) ...
Diffuse myelitis in a 9-month-old infant: case report and review of the literature ... Diffuse myelitis in a 9-month-old infant: case report and review of the literature ... Acute transverse myelitis affects all ages except children under 2 years. The present case was 9 months old and to our ... Acute transverse myelitis: MR characteristics. Neurology India, 1999, 47:290-3.. *Lahat E et al. Rapid recovery from transverse ...
Acute Flaccid Myelitis (AFM) August 2020. Jenny Abercrombie2020-10-27T14:26:22-07:00 August 21, 2020 ...
... ... Title : Acute Flaccid Myelitis in the United States, August-December 2014: Results of Nationwide Surveillance Personal Author(s ... Title : Enterovirus D68 in the Anterior Horn Cells of a Child with Acute Flaccid Myelitis Personal Author(s) : Vogt, Matthew R ... Acute Flaccid Myelitis in the United States, August-December 2014: Results of Nationwide Surveillance ...
Southwestern Polio-myelitis Respiratory Center at Jefferson Davis Hospital. Building exterior. ... Texas Medical Center, "Southwestern Polio-myelitis Respiratory Center at Jefferson Davis Hospital" (1951). Texas Medical Center ...
  • Neuroimaging studies disclosed laminar cortical necrosis and longitudinally extensive transverse myelitis (LETM) in cervical and thoracic spinal cord levels (figure). (unifesp.br)
  • Transverse myelitis is a neurological disorder caused by inflammation of the spinal cord. (nih.gov)
  • Myelitis refers to inflammation of the spinal cord. (nih.gov)
  • If the myelitis affects the upper spinal cord, it affects the arms as well. (nih.gov)
  • Myelitis is inflammation of the spinal cord which can disrupt the normal responses from the brain to the rest of the body, and from the rest of the body to the brain. (wikipedia.org)
  • however, any inflammatory attack on the spinal cord is often referred to as transverse myelitis. (wikipedia.org)
  • Immune-mediated myelopathies, heterogeneous group of inflammatory spinal cord disorders including autoimmune disorders with known antibodies Myelitis occurs due to various reasons such as infections. (wikipedia.org)
  • In the case of myelitis, not only is the immune system dysfunctional, but the dysfunction also crosses this protective blood brain barrier to affect the spinal cord. (wikipedia.org)
  • Poliomyelitis, or gray matter myelitis, is usually caused by infection of anterior horn of the spinal cord by the enteroviruses (polioviruses, enteroviruses (EV) 70 and 71, echoviruses, coxsackieviruses A and B) and the flaviviruses (West Nile, Japanese encephalitis, tick-borne encephalitis). (wikipedia.org)
  • Acute flaccid myelitis (AFM) is a medical condition characterized by muscular weakness and myelitis, which is the medical term used to describe inflammation of the spinal cord. (news-medical.net)
  • AFM is classified as a sub-type or variant of transverse myelitis, which clinically presents with symptoms and signs that are typical of neurologic dysfunction in the sensory and motor tracts on both sides of the spinal cord. (news-medical.net)
  • Sensory abnormalities are not typically found in testing, because the myelitis is limited to exclusively the gray matter of the spinal cord. (news-medical.net)
  • The term "myelitis" means inflammation of the spinal cord. (clevelandclinic.org)
  • Acute flaccid myelitis (AFM) is a rare condition that affects the spinal cord. (akronchildrens.org)
  • In most cases, transverse myelitis occurs due to an issue that is causing inflammation in the spinal cord. (nm.org)
  • Acute transverse myelitis is acute inflammation of gray and white matter in one or more adjacent spinal cord segments, usually thoracic. (msdmanuals.com)
  • Acute transverse myelitis is a rare but severe inflammatory demyelinating disorder that usually involves both sensory and motor tracts of the spinal cord [1]. (who.int)
  • Acute flaccid myelitis (AFM) is characterized by rapid onset of flaccid weakness in one or more limbs and distinct abnormalities of the spinal cord gray matter on magnetic resonance imaging (MRI). (cdc.gov)
  • Transverse myelitis is an inflammation of the spinal cord. (symptoma.com)
  • Idiopathic acute transverse myelitis (ATM) is an inflammation in the spinal cord that develops suddenly. (und.edu)
  • In people with transverse myelitis, the myelin damage most often occurs in nerves in the upper back, causing problems with leg movement and bowel and bladder control, which require signals from the lower segments of the spinal cord. (neurologycolorado.com)
  • Additional research funded by NINDS aims to develop new imaging techniques to assess the relationship between spinal cord pathology and neurological dysfunction in multiple sclerosis, which may possibly aid in other myelin disorders such as transverse myelitis. (neurologycolorado.com)
  • The term "myelitis" is too frequently loosely employed to designate cases of diffuse nonsystemic disease of the spinal cord in which the pathologic process bears no relation to infection but is due to toxins, avitaminosis, vascular disease, trauma, compression and similar causes. (jamanetwork.com)
  • Acute flaccid myelitis (AFM) is an emerging disorder primarily affecting children that is characterized by acute flaccid paralysis accompanied by abnormalities of the spinal cord gray matter on magnetic resonance imaging. (medscape.com)
  • However, AFM remains a rare disease, which can make it challenging for physicians to recognize and differentiate from other causes of acute flaccid paralysis such as Guillain-Barre syndrome, spinal cord stroke, and transverse myelitis. (medscape.com)
  • Acute flaccid myelitis (AFM) is a recently recognized disorder of the spinal cord characterized by acute-onset flaccid paralysis with associated gray matter-predominant abnormalities on magnetic resonance imaging (MRI) of the spinal cord. (medscape.com)
  • Transverse Myelitis, or TM, causes swelling on one or both sides of the spinal cord. (rxinjuryhelp.com)
  • Pain: Pain associated with traverse myelitis will depend on the area of the spinal cord affected. (rxinjuryhelp.com)
  • A s of this week, almost 200 children across 39 different states have been diagnosed with acute flaccid myelitis (AFM), a condition that affects the nervous system, especially in the area of spinal gray matter, weakening muscles and reflexes. (elitelearning.com)
  • Transverse myelitis is a rare neurological condition in which the entire width of the spinal cord becomes inflamed, causing nerve damage and pain . (vaccineinjurylegalteam.com)
  • There is a possible connection between Covid-19 and a rare spinal disorder known as transverse myelitis . (sciatica.clinic)
  • Although these case reports are not enough to prove that covid is the cause for transverse myelitis, researchers are delving into the possibility of a connection between the virus and this spinal condition. (sciatica.clinic)
  • Transverse myelitis (TM) is an inflammatory disease that causes injury to the spinal cord with varying degrees of weakness, sensory alterations, and autonomic dysfunction. (greenlegalteam.com)
  • Transverse myelitis is a group of disorders associated with spinal cord swelling. (pva.org)
  • Today, as part of the CDC Expert Commentary series on Medscape, I'll provide an update on acute flaccid myelitis (AFM), which we've been investigating since 2014 when we received an increase in reports in the United States. (medscape.com)
  • The latest update on acute flaccid myelitis, including case counts. (keepkidshealthy.com)
  • The Centers for Disease Control and Prevention (CDC) has noted an increase in reported and confirmed Acute Flaccid Myelitis (AFM) cases in 2018. (azdhs.gov)
  • Acute Flaccid Myelitis (AFM): What Health Care Providers Need to Know , COCA Call, November 13, 2018. (keepkidshealthy.com)
  • 2019. Acute Flaccid Myelitis Causes and Diagnosis . (news-medical.net)
  • The CDC's July 2019 Vital Signs report included a summary of recent experience with acute flaccid myelitis (AFM). (chop.edu)
  • Some people will have only one episode of transverse myelitis, but others may have a recurrence, especially if an underlying illness, such as multiple sclerosis, caused the inflammation. (nih.gov)
  • Many individuals experience only one episode of transverse myelitis. (neurologycolorado.com)
  • In people with transverse myelitis, myelin damage most often occurs in nerves in the upper back. (nih.gov)
  • Most people with transverse myelitis have at least partial recovery, with most recovery taking place within the first three months after symptoms begin. (nih.gov)
  • Weakness of the legs and arms -People with transverse myelitis often have weakness in the legs that worsens rapidly. (nih.gov)
  • People with transverse myelitis can also lose sensation in parts of their bodies. (nih.gov)
  • Bowel and bladder dysfunction -People with transverse myelitis often have an increased frequency or urge to use the toilet, incontinence or urinary retention, and constipation. (nih.gov)
  • No effective cure currently exists for people with transverse myelitis. (neurologycolorado.com)
  • The hard facts are that while most people with transverse myelitis have at least a partial recovery, for some, however, recovery can continue for up to two years and longer. (sciatica.clinic)
  • Individuals diagnosed with transverse myelitis, or TM, following administration of the flu vaccine or another inoculation may be entitled to compensation. (rxinjuryhelp.com)
  • Most individuals diagnosed with transverse myelitis report a tight banding or girdle-like sensation around the trunk, with the area being very sensitive to touch. (greenlegalteam.com)
  • A recent increase in cases of a polio-like illness in children called Acute Flaccid Myelitis (AFM) has drawn attention to gaps in understanding of its causes and treatment. (nih.gov)
  • Acute Flaccid Myelitis is a polio-like illness that tends to start with symptoms of an upper respiratory tract illness and leads to flaccid paralysis. (libsyn.com)
  • In some people, transverse myelitis is the first symptom of an autoimmune or immune-mediated disease such as multiple sclerosis or neuromyelitis optica spectrum disorder. (nih.gov)
  • If complete transverse myelitis, obtain neuromyelitis optica (NMO)-immunoglobulin G (IgG) antibodies to assist in determining the cause. (hopkinsguides.com)
  • Myelitis attacks with neuromyelitis optica spectrum disorder (NMOSD) tend to be more severe and are associated with less recovery than attacks with multiple sclerosis. (greenlegalteam.com)
  • A person with transverse myelitis will often feel a band-like sensation across the trunk of the body and may experience sensory symptoms and weakness below that area. (nih.gov)
  • Acute flaccid myelitis: a polio-like syndrome that causes muscle weakness and paralysis. (wikipedia.org)
  • Most myelitis manifests fast progression in muscle weakness or paralysis starting with the legs and then arms with varying degrees of severity. (wikipedia.org)
  • It can include atopic myelitis, which causes weakness. (wikipedia.org)
  • Acute flaccid myelitis (AFM) is an incompletely understood neurologic disorder occurring in epidemic fashion causing weakness ranging from mild paresis to devastating paralysis in children and some adults. (nih.gov)
  • Acute flaccid myelitis (AFM) is a rare but serious syndrome (a pattern of symptoms) that causes limb weakness, mostly in children. (cdc.gov)
  • Transverse myelitis generally presents with rapidly progressing muscle weakness or paralysis, beginning with the legs and moving to the arms with varying degrees of severity. (greenlegalteam.com)
  • Symptoms of AFM: Acute flaccid myelitis (AFM) is characterized by the sudden onset of limb weakness and loss of muscle tone and reflexes. (kennedykrieger.org)
  • Atopic dermatitis: rarely associated with myelitis in children. (hopkinsguides.com)
  • Kira, J 1997, ' Atopic myelitis: a novel clinical entity ', Fukuoka igaku zasshi = Hukuoka acta medica , vol. 88, no. 10, pp. 319-324. (elsevierpure.com)
  • Transverse Myelitis Consortium Working Group (TMCWG) proposed diagnostic criteria for idiopathic ATM. (hopkinsguides.com)
  • If none of the tests are suggestive of a specific cause, a diagnosis of idiopathic transverse myelitis can be made. (wearesrna.org)
  • 19 When a healthcare provider diagnoses someone with "transverse myelitis," they are typically referring to idiopathic TM. (wearesrna.org)
  • Disease-associated transverse myelitis" refers to TM that occurs in a patient with an identified autoimmune disorder. (wearesrna.org)
  • Acute transverse myelitis occasionally recurs in patients with multiple sclerosis, SLE, or antiphospholipid syndrome. (msdmanuals.com)
  • It is well-documented that Multiple sclerosis, bacterial infections, and other viruses can cause transverse myelitis, research must continue to see if there is a connection to covid-19. (sciatica.clinic)
  • The term "AFP" is a generalized "umbrella" term and includes multiple clinical entities, including paralytic poliomyelitis, AFM, Guillain-Barré syndrome (GBS), acute transverse myelitis, toxic neuropathy, and muscle disorders. (cdc.gov)
  • Some cases of transverse myelitis occur on their own, but a number of conditions appear to cause the disorder, including immune system disorders, bacterial and viral infections, fungal infections, and various parasites. (neurologycolorado.com)
  • Researchers at the National Institute of Neurological Disorders and Stroke (NINDS) are working to better understand the process by which the immune system destroys or attacks myelin in transverse myelitis and autoimmune disorders. (neurologycolorado.com)
  • Transverse Myelitis can be caused by other immune system disorders, viral infections, bacterial infections and fungal infections. (greenlegalteam.com)
  • Direct infection by viruses, bacteria, mold, or parasites such as human immunodeficiency virus (HIV), human T-lymphotropic virus types I and II (HTLV-I/II), syphilis, lyme disease, and tuberculosis can cause myelitis but it can also be caused due to non-infectious or inflammatory pathway. (wikipedia.org)
  • Acute flaccid myelitis (mye-uh-LYE-tiss) often happens after a respiratory infection, such as a cold . (akronchildrens.org)
  • The mechanism of transverse myelitis is often unknown, but some cases follow viral infection or vaccination, suggesting an autoimmune reaction. (msdmanuals.com)
  • The knowledge gained from such research should lead to a greater knowledge of the mechanisms responsible for transverse myelitis and may ultimately provide a means to prevent and treat this disorder. (neurologycolorado.com)
  • Transverse myelitis, or TM, is a neurological disorder that often damages the myelin, the protective layer that covers nerve cell fibers. (rxinjuryhelp.com)
  • Myelitis lesions usually occur in a narrow region but can be spread and affect many areas. (wikipedia.org)
  • Transverse myelitis (TM) can occur in any person at any age. (clevelandclinic.org)
  • Transverse myelitis can affect people of any age, but a peak in incidence rates appears to occur between 10 and 19 years of age and 30 to 39 years of age. (neurologycolorado.com)
  • Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody. (nih.gov)
  • Viral myelitis Most viral myelitis is acute, but the retroviruses (such as HIV and HTLV) can cause chronic myelitis. (wikipedia.org)
  • Retrieved on November 30, 2023 from https://www.news-medical.net/health/Acute-Flaccid-Myelitis-Causes-and-Diagnosis.aspx. (news-medical.net)
  • Doctors Gates: Diagnostic Algorithm for Evaluation of Acute Myelopathies and Myelitis. (blogspot.com)
  • Diagnostic Algorithm for Evaluation of Acute Myelopathies and Myelitis. (blogspot.com)
  • Neurosarcoidosis: myelitis may be part of the spectrum of inflammation. (hopkinsguides.com)
  • Acute flaccid myelitis has made headlines recently, but what exactly is this strange disease that affects children? (medlineplus.gov)
  • Myelitis often follows after the infections or after vaccination. (wikipedia.org)
  • Strong consideration should be made to initiating HAART in all HIV CMV myelitis cases. (hopkinsguides.com)
  • In some rare cases, transverse myelitis can be caused by vaccines. (vaccineinjurylegalteam.com)
  • There have been 158 cases of acute flaccid myelitis (AFM) so far this year, with another 153 cases under investigation by the CDC and state and local health departments. (keepkidshealthy.com)
  • There have been three known cases of acute transverse myelitis brought on from covid-19 . (sciatica.clinic)
  • EV-D68 is also the main enterovirus responsible for cases of acute flaccid myelitis (AFM) during years when we see increases in AFM cases. (snohd.org)
  • The patient was diagnosed with diffuse myelitis and treated at first with intravenous (IV) immunoglobulin (400 mg/kg/day for 5 days). (who.int)
  • As previously stated, there is no cure for transverse myelitis, and treatment focuses on managing complications. (sciatica.clinic)
  • AFM causes many of the same symptoms as other neurologic diseases, such as transverse myelitis and Guillain-Barre syndrome . (medlineplus.gov)
  • The symptoms associated with AFM are often similar to other neurological conditions, such as transverse myelitis and Guillain-Barre syndrome (GBS). (news-medical.net)
  • Acute flaccid myelitis and Guillain-Barré syndrome in children: A comparative study with evaluation of diagnostic criteria. (nih.gov)